@article{SchroeterHoffmannVoigtetal.2014, author = {Schroeter, Rebecca and Hoffmann, Tamara and Voigt, Birgit and Meyer, Hanna and Bleisteiner, Monika and Muntel, Jan and J{\"u}rgen, Britta and Albrecht, Dirk and Becher, D{\"o}rte and Lalk, Michael and Evers, Stefan and Bongaerts, Johannes and Maurer, Karl-Heinz and Putzer, Harald and Hecker, Michael and Schweder, Thomas and Bremer, Erhard}, title = {Stress responses of the industrial workhorse Bacillus licheniformis to osmotic challenges}, series = {PLoS ONE}, volume = {8}, journal = {PLoS ONE}, number = {11}, publisher = {PLOS}, address = {San Francisco}, issn = {1932-6203}, doi = {10.1371/journal.pone.0080956}, pages = {e80956}, year = {2014}, abstract = {The Gram-positive endospore-forming bacterium Bacillus licheniformis can be found widely in nature and it is exploited in industrial processes for the manufacturing of antibiotics, specialty chemicals, and enzymes. Both in its varied natural habitats and in industrial settings, B. licheniformis cells will be exposed to increases in the external osmolarity, conditions that trigger water efflux, impair turgor, cause the cessation of growth, and negatively affect the productivity of cell factories in biotechnological processes. We have taken here both systems-wide and targeted physiological approaches to unravel the core of the osmostress responses of B. licheniformis. Cells were suddenly subjected to an osmotic upshift of considerable magnitude (with 1 M NaCl), and their transcriptional profile was then recorded in a time-resolved fashion on a genome-wide scale. A bioinformatics cluster analysis was used to group the osmotically up-regulated genes into categories that are functionally associated with the synthesis and import of osmostress-relieving compounds (compatible solutes), the SigB-controlled general stress response, and genes whose functional annotation suggests that salt stress triggers secondary oxidative stress responses in B. licheniformis. The data set focusing on the transcriptional profile of B. licheniformis was enriched by proteomics aimed at identifying those proteins that were accumulated by the cells through increased biosynthesis in response to osmotic stress. Furthermore, these global approaches were augmented by a set of experiments that addressed the synthesis of the compatible solutes proline and glycine betaine and assessed the growth-enhancing effects of various osmoprotectants. Combined, our data provide a blueprint of the cellular adjustment processes of B. licheniformis to both sudden and sustained osmotic stress.}, language = {en} } @article{HandtkeVollandMethlingetal.2014, author = {Handtke, Stefan and Volland, Sonja and Methling, Karen and Albrecht, Dirk and Becher, D{\"o}rte and Nehls, Jenny and Bongaerts, Johannes and Maurer, Karl-Heinz and Lalk, Michael and Liesegang, Heiko and Voigt, Birgit and Daniel, Rolf and Hecker, Michael}, title = {Cell physiology of the biotechnological relevant bacterium Bacillus pumilus - An omics-based approach}, series = {Journal of Biotechnology}, journal = {Journal of Biotechnology}, number = {192(A)}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-4863 (E-Journal); 0168-1656 (Print)}, doi = {10.1016/j.jbiotec.2014.08.028}, pages = {204 -- 214}, year = {2014}, abstract = {Members of the species Bacillus pumilus get more and more in focus of the biotechnological industry as potential new production strains. Based on exoproteome analysis, B. pumilus strain Jo2, possessing a high secretion capability, was chosen for an omics-based investigation. The proteome and metabolome of B. pumilus cells growing either in minimal or complex medium was analyzed. In total, 1542 proteins were identified in growing B. pumilus cells, among them 1182 cytosolic proteins, 297 membrane and lipoproteins and 63 secreted proteins. This accounts for about 43\% of the 3616 proteins encoded in the B. pumilus Jo2 genome sequence. By using GC-MS, IP-LC/MS and H NMR methods numerous metabolites were analyzed and assigned to reconstructed metabolic pathways. In the genome sequence a functional secretion system including the components of the Sec- and Tat-secretion machinery was found. Analysis of the exoproteome revealed secretion of about 70 proteins with predicted secretion signals. In addition, selected production-relevant genome features such as restriction modification systems and NRPS clusters of B. pumilus Jo2 are discussed.}, language = {en} } @inproceedings{ButenwegRajan2014, author = {Butenweg, Christoph and Rajan, Sreelakshmy}, title = {Design and construction techniques of AAC masonry buildings in earthquakes regions}, series = {10 years Xella research in Building Materials : Symposium on the 4th and 5th of September, Potsdam 2014}, booktitle = {10 years Xella research in Building Materials : Symposium on the 4th and 5th of September, Potsdam 2014}, year = {2014}, language = {en} } @inproceedings{MaikeLenzWolf2014, author = {Maike, M{\"u}ller and Lenz, Laura and Wolf, Martin R.}, title = {Steigerung der Effektivit{\"a}t durch Prozessmodellierungs-Tools - {\"A}nderbarkeit und Transparenz von Prozessen am Beispiel der Business Simulation Apollo 13}, series = {Informatik 2014}, booktitle = {Informatik 2014}, publisher = {Gesellschaft f{\"u}r Informatik e.V.}, address = {Bonn}, isbn = {978-3-88579-626-8}, issn = {1617-5468}, pages = {357 -- 369}, year = {2014}, abstract = {Die Nutzung von Prozessmodellierungsmethoden oder - werkzeugen kann erheblichen Einfluss auf die Effektivit{\"a}t von Prozessen haben. Das gilt insbesondere f{\"u}r Situationen, in denen Personen unter Stress stehen oder unge{\"u}bt sind. In diesen F{\"a}llen geben Prozessmodelle konkrete Empfehlungen, nach denen sich die handelnden Personen richten k{\"o}nnten. In Experimenten mit der Business-Simulation Apollo 13 haben wir den Effekt eines Einsatzes von Prozessmodellierungsmethoden und -werkzeugen untersucht. Bereits bekannte Theorien (z.B. {\"u}ber geeignete Verh{\"a}ltnisse von Kommunikationsinhalten) konnten best{\"a}tigt werden. Dar{\"u}ber hinaus haben wir eine besondere Bedeutung der {\"U}bertragbarkeit von Prozessmodellen in konkrete Handlungen identifiziert.}, language = {de} } @inproceedings{LenzWolf2014, author = {Lenz, Laura L. and Wolf, Martin R.}, title = {Economic evaluation of serious games with the comparative assessment framework COSEGA}, series = {The shift from teaching to learning : individual, collective and organizational learning through gaming simulation ; proceedings of the 45th conference of the International Simulation and Gaming Association, Dornbirn 2014}, booktitle = {The shift from teaching to learning : individual, collective and organizational learning through gaming simulation ; proceedings of the 45th conference of the International Simulation and Gaming Association, Dornbirn 2014}, editor = {Kritz, Willy Christian}, publisher = {Bertelsmann}, address = {[Bielefeld]}, isbn = {978-3-7639-5422-3}, pages = {374 -- 386}, year = {2014}, language = {en} } @misc{AlKaidyTippkoetterKaiseretal.2014, author = {Al-Kaidy, H. and Tippk{\"o}tter, Nils and Kaiser, P. and Wollny, S. and Ulber, Roland}, title = {Aufreinigung von Cytochrom P450BMP mittels magnetischer Partikel und die enzymatische Synthese von 9, 10-Dihydroxystearins{\"a}ure}, series = {Chemie Ingenieur Technik}, volume = {86}, journal = {Chemie Ingenieur Technik}, number = {9}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201450420}, pages = {1420}, year = {2014}, abstract = {Cytochrom P450 sind H{\"a}m-Proteine, die zur Enzymklasse der Oxidoreduktasen (EC 1.14.xy) geh{\"o}ren. Eine wichtige Reaktion ist die Hydroxylierung nichtaktivierter C-H-Bindungen, die in technischen Systemen von großem Interesse ist. Durch die Verwendung von M-IDA-2-Partikeln ist eine direkte Aufreinigung mit gleichzeitiger Immobilisierung und die Applikation der Enzyme aus dem Zelllysat m{\"o}glich. Damit ist das Verfahren mehr als f{\"u}nf Stunden schneller als die konventionelle Chromatographie und mehr als 80 \% der Aufreinigungszeit wird gespart. Mit dem isolierten nativen Enzym konnte die Plattformchemikalie 9,10-Dihydroxystearins{\"a}ure aus {\"O}ls{\"a}ure hergestellt werden. Unter anderem f{\"u}r die Kunststoffindustrie k{\"o}nnen aus diesem Produkt wichtige Monomere wie z. B. Azelains{\"a}ure hergestellt werden. Die Bildung des Produkts erfolgt in einem zweiphasigen Reaktionssystem an der Grenzfl{\"a}che zwischen dem {\"O}l und der w{\"a}ssrigen Phase als Feststoff. Um das immobilisierte Enzym aktiv in die obere Phase zu transportieren, wurde eine neue magnetische Mischvorrichtung entwickelt. Das Reaktionsprodukt wurde mit NMR, GC-MS und HPLC-MS analysiert und mit einem chemisch synthetisierten Standard von 9,10-Dihydroxystearins{\"a}ure verglichen. Derzeit werden Studien des immobilisierten H{\"a}ms des Enzyms durchgef{\"u}hrt.}, language = {de} } @article{KluczkaEcksteinAlexopoulosetal.2014, author = {Kluczka, Sven and Eckstein, Julian and Alexopoulos, Spiros and Vaeßen, Christiane and Roeb, Martin}, title = {Process simulation for solar steam and dry reforming}, series = {Energy procedia : Proceedings of the SolarPACES 2013 International Conference}, volume = {49}, journal = {Energy procedia : Proceedings of the SolarPACES 2013 International Conference}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1876-6102 (E-Journal)}, doi = {10.1016/j.egypro.2014.03.092}, pages = {850 -- 859}, year = {2014}, abstract = {In co-operation with the German Aerospace Center, the Solar-Institut J{\"u}lich has been analyzing the different technologies that are available for methanol production from CO2 using solar energy. The aim of the project is to extract CO2 from industrial exhaust gases or directly from the atmosphere to recycle it by use of solar energy. Part of the study was the modeling and simulating of a methane reformer for the production of synthesis gas, which can be operated by solar or hybrid heat sources. The reformer has been simplified in such a way that the model is accurate and enables fast calculations. The developed pseudo-homogeneous one- dimensional model can be regarded as a kind of counter-current heat exchanger and is able to incorporate a steam reforming reaction as well as a dry reforming reaction.}, language = {en} } @misc{TippkoetterWasserscheid2014, author = {Tippk{\"o}tter, Nils and Wasserscheid, P.}, title = {Rapid-Prototyping-Strukturen f{\"u}r ressourceneffiziente Prozesse in Chemie und Biotechnologie}, series = {Chemie Ingenieur Technik}, volume = {86}, journal = {Chemie Ingenieur Technik}, number = {9}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201450451}, pages = {1369 -- 1370}, year = {2014}, abstract = {Die Teilefertigung durch Rapid Prototyping (RP) verk{\"u}rzt den Weg von der Idee bis zum Produkt, wobei unter anderem Optimierungszyklen in geringer Zeit durchlaufen werden k{\"o}nnen. Ferner er{\"o}ffnen neue Entwicklungen in diesem Bereich die M{\"o}glichkeit individueller Produktionsverfahren. Im Unterschied zur klassischen Fertigung von Prototypen wird beim RP mit additiver Schichtfertigung (Additive Layer Manufacturing, ALM) gearbeitet. Je nach Methode werden Fl{\"u}ssigkeiten oder Pulver nach Vorgaben eines 3D-Computermodells sequentiell aufgetragen. Diese Verfahren existieren seit ca. 25 Jahren, jedoch sind seit kurzem ausgesprochen g{\"u}nstige Ger{\"a}te verf{\"u}gbar, die Objekte mit Genauigkeiten bis 20 lm fertigen k{\"o}nnen. Das RP hat in klinischen Anwendungsgebieten bzw. im Bereich des Tissue Engineering bereits vielfach Einzug gefunden. Aber auch chemisch-biotechnologische Entwicklungen k{\"o}nnen von den Verfahren profitieren. So wurden Mikrofluidiksysteme und Bioreaktoren bereits erfolgreich durch RP gefertigt. Durch ALM ist ebenso die Herstellung von Reaktionseinheiten aus biokompatiblen Materialien wie ionotropen Gelen m{\"o}glich. Ferner sind sehr komplexe Strukturierungen von Oberfl{\"a}chen im Nanometerbereich realisierbar, die f{\"u}r die Auftragung heterogener Katalysatoren oder auch Mikroorganismen eingesetzt werden k{\"o}nnen. Auch der Bereich Reaktoren- und Apparatebau kann von den Fortschritten in der additiven Fertigung profitieren. Verfahren wie selektives Laser- oder Elektronenstrahlschmelzen erlauben es, metallische Komponenten in nahezu beliebigen Geometrien zu fertigen. Somit k{\"o}nnen Strukturen verwirklicht werden, die mit konventionellen Fertigungstechniken nur sehr schwer oder {\"u}berhauptnicht herstellbar w{\"a}ren. Durch Anwendung von rechnergest{\"u}tzter Modellierung k{\"o}nnen optimale Strukturen identifiziert und additiv gefertigt werden. Eine anschließende katalytische Funktionalisierung der Oberfl{\"a}che erm{\"o}glicht die Herstellung strukturierter Reaktoren mit maßgeschneiderten Eigenschaften.}, language = {de} } @inproceedings{OegunKlingHeuermannetal.2014, author = {{\"O}gun, Celal Mohan and Kling, Rainer and Heuermann, Holger and Gr{\"a}ser, Ulrich and Schopp, Christoph}, title = {Elektrodenlose quecksilberfreie Niederdrucklampen betrieben mit Mikrowellen}, series = {Licht 2014 [Elektronische Ressource] : Den Haag, Holland ; 21. Gemeinschaftstagung, 21. bis 24. September 2014 ; Tagungsband}, booktitle = {Licht 2014 [Elektronische Ressource] : Den Haag, Holland ; 21. Gemeinschaftstagung, 21. bis 24. September 2014 ; Tagungsband}, publisher = {Nederlandse Stichting voor Verlichtingskunde}, address = {Ede}, pages = {[Elektronische Ressource]}, year = {2014}, language = {de} } @incollection{Laack2014, author = {Laack, Walter van}, title = {Gefahren heutiger neurologischer Schlussfolgerungen f{\"u}r ethische Verantwortung}, series = {Ethik und Moral in Staat, Wirtschaft und Gesellschaft : 5. Rotary-Tag, 14.-15.2.2014, Kleve}, booktitle = {Ethik und Moral in Staat, Wirtschaft und Gesellschaft : 5. Rotary-Tag, 14.-15.2.2014, Kleve}, publisher = {Edition Virgines}, address = {Lingen}, organization = {Rotary-Tag <5, 2014, Kleve>}, isbn = {978-3-944011-21-9}, pages = {98 -- 114}, year = {2014}, language = {de} } @inproceedings{RitzIzquierdoTelloDamm2014, author = {Ritz, Thomas and Izquierdo Tello, C{\´e}sar and Damm, Sebastian}, title = {Connecting a pedelec to the cloud as basis for gamification in multi modal mobility planning}, series = {MobileCloud 2014 : 2nd IEEE International Conference on Mobile Cloud Computing, Services, and Engineering Oxford, United Kingdom 7-10 April 2014}, booktitle = {MobileCloud 2014 : 2nd IEEE International Conference on Mobile Cloud Computing, Services, and Engineering Oxford, United Kingdom 7-10 April 2014}, publisher = {IEEE Service Center}, address = {Piscataway, NJ}, isbn = {978-1-4799-2504-9}, doi = {10.1109/MobileCloud.2014.25}, pages = {101 -- 108}, year = {2014}, language = {en} } @article{SchusserBaeckerKrischeretal.2014, author = {Schusser, Sebastian and B{\"a}cker, Matthias and Krischer, M. and Wenzel, L. and Leinhos, Marcel and Poghossian, Arshak and Biselli, Manfred and Wagner, P. and Sch{\"o}ning, Michael Josef}, title = {Enzymatically catalyzed degradation of biodegradable polymers investigated by means of a semiconductor-based field-effect sensor}, series = {Procedia Engineering}, volume = {87}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2014.11.689}, pages = {1314 -- 1317}, year = {2014}, abstract = {A semiconductor field-effect device has been used for an enzymatically catalyzed degradation of biopolymers for the first time. This novel technique is capable to monitor the degradation process of multiple samples in situ and in real-time. As model system, the degradation of the biopolymer poly(D, L-lactic acid) has been monitored in the degradation medium containing the enzyme lipase from Rhizomucor miehei. The obtained results demonstrate the potential of capacitive field-effect sensors for degradation studies of biodegradable polymers.}, language = {en} } @inproceedings{JungStaatMueller2014, author = {Jung, Alexander and Staat, Manfred and M{\"u}ller, Wolfram}, title = {Optimization of the flight style in ski jumping}, series = {11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20 - 25, 2014, Barcelona}, booktitle = {11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20 - 25, 2014, Barcelona}, editor = {Onate, E.}, organization = {World Congress on Computational Mechanics <11, 2014, Barcelona>}, pages = {799 -- 810}, year = {2014}, language = {en} } @article{PoghossianSchoening2014, author = {Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Label-free sensing of biomolecules with field-effect devices for clinical applications}, series = {Electroanalysis}, volume = {26}, journal = {Electroanalysis}, number = {6}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1521-4109 (E-Journal); 1040-0397 (Print)}, doi = {10.1002/elan.201400073}, pages = {1197 -- 1213}, year = {2014}, abstract = {Among the variety of transducer concepts proposed for label-free detection of biomolecules, the semiconductor field-effect device (FED) is one of the most attractive platforms. As medical techniques continue to progress towards diagnostic and therapies based on biomarkers, the ability of FEDs for a label-free, fast and real-time detection of multiple pathogenic and physiologically relevant molecules with high specificity and sensitivity offers very promising prospects for their application in point-of-care and personalized medicine for an early diagnosis and treatment of diseases. The presented paper reviews recent advances and current trends in research and development of different FEDs for label-free, direct electrical detection of charged biomolecules by their intrinsic molecular charge. The authors are mainly focusing on the detection of the DNA hybridization event, antibody-antigen affinity reaction as well as clinically relevant biomolecules such as cardiac and cancer biomarkers.}, language = {en} } @article{LeinhosSchusserBaeckeretal.2014, author = {Leinhos, Marcel and Schusser, Sebastian and B{\"a}cker, Matthias and Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Micromachined multi-parameter sensor chip for the control of polymer-degradation medium}, series = {Physica Status Solidi (A) : special issue on engineering and functional interfaces}, volume = {211}, journal = {Physica Status Solidi (A) : special issue on engineering and functional interfaces}, number = {6}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)}, doi = {10.1002/pssa.201330364}, pages = {1346 -- 1351}, year = {2014}, abstract = {It is well known that the degradation environment can strongly influence the biodegradability and kinetics of biodegradation processes of polymers. Therefore, besides the monitoring of the degradation process, it is also necessary to control the medium in which the degradation takes place. In this work, a micromachined multi-parameter sensor chip for the control of the polymer-degradation medium has been developed. The chip combines a capacitive field-effect pH sensor, a four-electrode electrolyte-conductivity sensor and a thin-film Pt-temperature sensor. The results of characterization of individual sensors are presented. In addition, the multi-parameter sensor chip together with an impedimetric polymer-degradation sensor was simultaneously characterized in degradation solutions with different pH and electrolyte conductivity. The obtained results demonstrate the feasibility of the multi-parameter sensor chip for the control of the polymer-degradation medium.}, language = {en} } @article{HuckPoghossianBaeckeretal.2014, author = {Huck, Christina and Poghossian, Arshak and B{\"a}cker, Matthias and Chaudhuri, S. and Zander, W. and Schubert, J. and Begoyan, V. K. and Buniatyan, V. V. and Wagner, P. and Sch{\"o}ning, Michael Josef}, title = {Capacitively coupled electrolyte-conductivity sensor based on high-k material of barium strontium titanate}, series = {Sensors and actuators. B: Chemical}, journal = {Sensors and actuators. B: Chemical}, number = {198}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-3077 (E-Journal); 0925-4005 (Print)}, doi = {10.1016/j.snb.2014.02.103}, pages = {102 -- 109}, year = {2014}, language = {en} } @article{BaeckerKramerHucketal.2014, author = {B{\"a}cker, Matthias and Kramer, F. and Huck, Christina and Poghossian, Arshak and Bratov, A. and Abramova, N. and Sch{\"o}ning, Michael Josef}, title = {Planar and 3D interdigitated electrodes for biosensing applications: The impact of a dielectric barrier on the sensor properties}, series = {Physica Status Solidi (A) - Applications and Materials Science}, volume = {211}, journal = {Physica Status Solidi (A) - Applications and Materials Science}, number = {6}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)}, doi = {10.1002/pssa.201330416}, pages = {1357 -- 1363}, year = {2014}, abstract = {Planar and three-dimensional (3D) interdigitated electrodes (IDE) with electrode digits separated by an insulating barrier of different heights were electrochemically characterized and compared in terms of their sensing properties. Due to the impact of the surface resistance, both types of IDE structures display a non-linear behavior in low-ionic strength solutions. The experimental data were fitted to an electrical equivalent circuit and interpreted taking into account the surface-charge-governed properties. The effect of a charged polyelectrolyte layer electrostatically assembled onto the sensor surface on the surface resistance in solutions with different KCl concentration is studied. In case of the same electrode footprint, 3D-IDEs show a larger cell constant and a higher sensitivity to molecular adsorption than that of planar IDEs. The obtained results demonstrate the potential of 3D-IDEs as a new transducer structure for a direct label-free sensing of charged molecules.}, language = {en} } @article{MoseleyHalamekKrameretal.2014, author = {Moseley, Fiona and Halamek, Jan and Kramer, Friederike and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Katz, Evgeny}, title = {An enzyme-based reversible CNOT logic gate realized in a flow system}, series = {Analyst}, volume = {139}, journal = {Analyst}, number = {8}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1364-5528 (E-Journal) ; 0003-2654 (Print)}, doi = {10.1039/C4AN00133H}, pages = {1839 -- 1842}, year = {2014}, abstract = {An enzyme system organized in a flow device was used to mimic a reversible Controlled NOT (CNOT) gate with two input and two output signals. Reversible conversion of NAD⁺ and NADH cofactors was used to perform a XOR logic operation, while biocatalytic hydrolysis of p-nitrophenyl phosphate resulted in an Identity operation working in parallel. The first biomolecular realization of a CNOT gate is promising for integration into complex biomolecular networks and future biosensor/biomedical applications.}, language = {en} } @incollection{McInnesBothmerDachwaldetal.2014, author = {McInnes, Colin R. and Bothmer, Volker and Dachwald, Bernd and Geppert, Ulrich R. M. E. and Heiligers, Jeannette and Hilgers, Alan and Johnson, Les and Macdonald, Malcolm and Reinhard, Ruedeger and Seboldt, Wolfgang and Spietz, Peter}, title = {Gossamer roadmap technology reference study for a Sub-L1 Space Weather Mission}, series = {Advances in solar sailing}, booktitle = {Advances in solar sailing}, publisher = {Springer}, address = {Berlin [u.a.]}, isbn = {978-3-642-34906-5 (Print) ; 978-3-642-34907-2 (E-Book)}, pages = {227 -- 242}, year = {2014}, abstract = {A technology reference study for a displaced Lagrange point space weather mission is presented. The mission builds on previous concepts, but adopts a strong micro-spacecraft philosophy to deliver a low mass platform and payload which can be accommodated on the DLR/ESA Gossamer-3 technology demonstration mission. A direct escape from Geostationary Transfer Orbit is assumed with the sail deployed after the escape burn. The use of a miniaturized, low mass platform and payload then allows the Gossamer-3 solar sail to potentially double the warning time of space weather events. The mission profile and mass budgets will be presented to achieve these ambitious goals.}, language = {en} } @misc{DuweSchlegelTippkoetteretal.2014, author = {Duwe, A. and Schlegel, C. and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {Sequentielle Extraktion von Cellulose zur effizienten Nutzung der Stoffstr{\"o}me in der Holzbioraffinerie}, series = {Chemie Ingenieur Technik}, volume = {86}, journal = {Chemie Ingenieur Technik}, number = {9}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201450308}, pages = {1400}, year = {2014}, abstract = {In der Reihe der nachwachsenden Rohstoffe besitzt Holz als erneuerbare und umweltfreundliche Ressource ein großes Potenzial. {\"U}ber 11 Mio. ha Holz, das laut der Fachagentur f{\"u}r nachwachsende Rohstoffe (FNR) auch f{\"u}r industrielle Zwecke genutzt werden kann, wuchsen im Jahr 2013 allein auf bundesdeutscher Fl{\"a}che. 56,8 Mio. m³ j{\"a}hrlicher Holzeinschlag in den letzten zehn Jahren wurde zu knapp der H{\"a}lfte stofflich und der Rest energetisch verwertet. Im Rahmen dieser Arbeit konnte auf der Basis vom Holz der Buche, die nach Fichte und Kiefer die dritth{\"a}ufigste Baumart in Deutschland ist und 15\% der deutschen Waldfl{\"a}che ausmacht, die Fraktionierung der polymeren Hauptbestandteile mit niedrigem energetischen Einsatz erreicht werden. Hierbei werden in einem nachgeschalteten Extraktionsprozess die beiden Komponenten Hemicellulose und Lignin in fl{\"u}ssiger Form von der finalen festen Cellulosefraktion abgetrennt. Die Extraktion der Hemicellulose erfolgt durch eine Liquid Hot Water (LHW)-Behandlung. Untersucht wird der katalytische Zusatz anorganischer S{\"a}uren wie H₃PO₄ und H₂SO₄. Im Hinblick auf die weitere Verwertung von Lignin zu aromatischen Synthesebausteinen kommt die Organosolv-Extraktion mit einem Ethanol/Wasser-Gemisch zum Einsatz. Von Vorteil ist die weitere Verwendung beider Stoffstr{\"o}me ohne F{\"a}llungsschritt und nachteiliger Verd{\"u}nnung der Hemicellulose.}, language = {en} } @article{HuckPoghossianBaeckeretal.2014, author = {Huck, Christina and Poghossian, Arshak and B{\"a}cker, Matthias and Reisert, Steffen and Schubert, J. and Zander, W. and Begoyan, V. K. and Buniatyan, V. V. and Sch{\"o}ning, Michael Josef}, title = {Chemical sensors based on a high-k perovskite oxide of barium strontium titanate}, series = {Procedia Engineering}, volume = {87}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2014.11.258}, pages = {28 -- 31}, year = {2014}, abstract = {High-k perovskite oxide of barium strontium titanate (BST) represents a very attractive multi-functional transducer material for the development of (bio-)chemical sensors for liquids. In this work, BST films have been applied as a sensitive transducer material for a label-free detection of adsorbed charged macromolecules (positively charged polyelectrolytes) and concentration of hydrogen peroxide vapor as well as protection insulator layer for a contactless electrolyte-conductivity sensor. The experimental results of characterization of individual sensors are presented. Special emphasis is devoted towards the development of a capacitively-coupled contactless electrolyte-conductivity sensor.}, language = {en} } @techreport{PisarczykRitzWallenborn2014, author = {Pisarczyk, Rafael and Ritz, Thomas and Wallenborn, Ramona}, title = {Unterschiedliche Entwicklungsans{\"a}tze von Multiplattform-Anwendungen : Markt{\"u}bersicht}, publisher = {eBusiness-Lotse}, address = {Aachen}, pages = {15 S. : Ill., graph. Darst.}, year = {2014}, abstract = {Die Markt{\"u}bersicht „Unterschiedliche Entwicklungsans{\"a}tze von Multiplattform-Anwendungen" richtet sich an IT-Dienstleister, Entwickler und IT-Abteilungen von Unternehmen, die Multiplattform Anwendungen entwickeln. In dieser Markt{\"u}bersicht werden verschiedene Entwicklungsans{\"a}tze beschrieben und ihre jeweiligen Vor- und Nachteile aufgezeigt.}, language = {de} } @article{TippkoetterDuweWiesenetal.2014, author = {Tippk{\"o}tter, Nils and Duwe, Anna-Maria and Wiesen, Sebastian and Sieker, Tim and Ulber, Roland}, title = {Enzymatic hydrolysis of beech wood lignocellulose at high solid contents and its utilization as substrate for the production of biobutanol and dicarboxylic acids}, series = {Bioresource Technology}, volume = {167}, journal = {Bioresource Technology}, publisher = {Elsevier}, address = {Amsterdam}, doi = {10.1016/j.biortech.2014.06.052}, pages = {447 -- 455}, year = {2014}, abstract = {The development of a cost-effective hydrolysis for crude cellulose is an essential part of biorefinery developments. To establish such high solid hydrolysis, a new solid state reactor with static mixing is used. However, concentrations >10\% (w/w) cause a rate and yield reduction of enzymatic hydrolysis. By optimizing the synergetic activity of cellulolytic enzymes at solid concentrations of 9\%, 17\% and 23\% (w/w) of crude Organosolv cellulose, glucose concentrations of 57, 113 and 152 g L⁻¹ are reached. However, the glucose yield decreases from 0.81 to 0.72gg⁻¹ at 17\% (w/w). Optimal conditions for hydrolysis scale-up under minimal enzyme addition are identified. As result, at 23\% (w/w) crude cellulose the glucose yield increases from 0.29 to 0.49gg⁻¹. As proof of its applicability, biobutanol, succinic and itaconic acid are produced with the crude hydrolysate. The potential of the substrate is proven e.g. by a high butanol yield of 0.33gg⁻¹.}, language = {en} } @misc{HeringPasteurWollnyetal.2014, author = {Hering, T. and Pasteur, A. and Wollny, S. and Ulber, Roland and Tippk{\"o}tter, Nils}, title = {Magnetische Separation von Gold-Nanopartikeln zur Glucons{\"a}ure-Produktion durch Hochgradient-Magnetseparation im Labormaßstab}, series = {Chemie Ingenieur Technik}, volume = {86}, journal = {Chemie Ingenieur Technik}, number = {9}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201450265}, pages = {1501}, year = {2014}, abstract = {Bei der Verarbeitung nachwachsender Rohstoffe entsteht aus Cellulose oder St{\"a}rke u. a. das wichtige Produkt Glucose. Diese niedermolekulare Kohlenhydratquelle wird {\"u}blicherweise als Substrat f{\"u}r biotechnologische und chemische Synthesen verwendet. Ein wirtschaftlich interessantes Oxidationsprodukt der Glucose ist Glucons{\"a}ure, die beispielsweise als Lebensmittelzusatzstoff (E 574), in der Medizin und Metallindustrie Verwendung findet. Die Umsetzung des Monosaccharids zu Glucons{\"a}ure erfolgt entweder durch mikrobielle Fermentation oder der Oxidation an heterogenen Katalysatoren. Die Zielsetzung der Studie ist die Untersuchung der Glucoseoxidation an magnetisierbaren Gold-Nanopartikeln unter nachfolgender Bypass-Separation des Katalysators mittels einer neuen Mini-HGMS-Einheit (Hochgradient-Magnetseparation). Dieser Filtertyp erm{\"o}glicht die selektive Trennung magnetischer Partikel aus Suspensionen mit hohem Feststoffgehalt oder Viskosit{\"a}t. Erste Ergebnisse zeigen eine Beladungskapazit{\"a}t des selbstkonstruierten Mini-HGMS von 550 mg goldbeschichteter magnetisierbarer Nanopartikel. Die Oxidation erfolgt bei einem pH-Wertvon 9, bei 40 °C und mit 100 mM Glucose in einem begasten R{\"u}hrkesselreaktor. Das System soll zuk{\"u}nftig zum Katalysatorrecycling von hochviskosen und Feststoffbelasteten Produktstr{\"o}men aus Bioraffinerien eingesetzt werden.}, language = {de} } @article{TippkoetterWollnySucketal.2014, author = {Tippk{\"o}tter, Nils and Wollny, Steffen and Suck, Kirstin and Sohling, Ulrich and Ruf, Friedrich and Ulber, Roland}, title = {Recycling of spent oil bleaching earth as source of glycerol for the anaerobic production of acetone, butanol, and ethanol with Clostridium diolis and lipolytic Clostridium lundense}, series = {Engineering in Life Sciences}, volume = {14}, journal = {Engineering in Life Sciences}, number = {4}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1618-2863}, doi = {10.1002/elsc.201300113}, pages = {425 -- 432}, year = {2014}, abstract = {A major part of edible oil is subjected to bleaching procedures, primarily with minerals applied as adsorbers. Their recycling is currently done either by regaining the oil via organic solvent extraction or by using the spent bleaching earth (SBE) as additive for animal feed, etc. As a new method, the reutilization of the by-product SBE for the microbiologic formation of acetone, butanol, and ethanol (ABE) is presented as proof-of-concept. The SBE was taken from a palm oil cleaning process. The recycling concept is based on the application of lipolytic clostridia strains. Due to considerably long fermentation times, co-fermentation with Candida rugosa and enzymatic hydrolyses of the bound oil with a subsequent clostridia fermentation are shown as alternative routes. Anaerobic fermentations under comparison of different clostridia strains were performed with glycerol media, enzymatically hydrolyzed palm oil and SBE. Solutes, side product compositions and productivities were quantified via HPLC. A successful production of ABE solutes from SBE has been done with a yield of 0.15 g butanol per gram of bound glycerol. Thus, the biotechnological recycling of the waste stream is possible in principle. Inhibition of the substrate suspension has been observed. A chromatographic ion-exchange of substrates increased the biomass concentration.}, language = {en} } @misc{HeringUlberTippkoetter2014, author = {Hering, T. and Ulber, Roland and Tippk{\"o}tter, Nils}, title = {Aktiver und passiver antimikrobieller Oberfl{\"a}chenschutz durch funktionalisierte Mikropartikel}, series = {Chemie Ingenieur Technik}, volume = {9}, journal = {Chemie Ingenieur Technik}, number = {86}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201450264}, pages = {1474 -- 1475}, year = {2014}, abstract = {Mikrobielle Verunreinigungen von Oberfl{\"a}chen in technischen und medizinischen Systemen sind allgegenw{\"a}rtig. Sie basieren {\"u}blicherweise auf adsorptiven Oberfl{\"a}chenbindungen organischer Komponenten (Proteine und Fette) oder Membrankomponenten aerogener sowie wassergebundener Mikroorganismen. In laufenden Forschungsarbeiten wird eine aktive sowie passive Biomodifikation von Oberfl{\"a}chen zu deren Schutz vor Adsorption von Proteinen und Mikroorganismen verfolgt. Der antimikrobielle Schutz soll dabei sowohl durch die Mikrostrukturierung bzw. Rauheitsanpassung der Oberfl{\"a}chen durch deren Beschichtung mit Mikro-und Nanopartikeln erfolgen. Ferner werden antimikrobielle Enzyme und funktionelle Gruppen auf den Mikropartikeln gebunden, um den Oberfl{\"a}chenschutz zu verst{\"a}rken. In ersten Versuchen wurden quart{\"a}re Ammoniumverbindungen auf eigens synthetisierten superparamagnetischen Eisenoxid-Nanopartikeln (Durchmesser 10 - 30 nm) immobilisiert und die wachstumshemmende Wirkung untersucht. Erste Ergebnisse zeigten, dass eine Konzentration von 10 mg mL⁻¹ der Ammoniumverbindung in einer Wachstumshemmung des verwendeten Gram-negativen Modell-Mikroorganismus E. coli GFPmut2 resultiert. Zurzeit werden synergistisch wirkende Kombinationen von Partikeln mit Proteasen, quart{\"a}ren Ammoniumverbindungen, hydrophoben Oberfl{\"a}chen und mikrostrukturierten Oberfl{\"a}chen als antimikrobieller Schutz untersucht.}, language = {de} } @article{HuckPoghossianKerroumietal.2014, author = {Huck, Christina and Poghossian, Arshak and Kerroumi, Iman and Schusser, Sebastian and B{\"a}cker, Matthias and Zander, Willi and Schubert, J{\"u}rgen and Buniatyan, Vahe V. and Martirosyan, Norayr W. and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Multiparameter sensor chip with Barium Strontium Titanate as multipurpose material}, series = {Electroanalysis}, volume = {26}, journal = {Electroanalysis}, number = {5}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1521-4109 (E-Journal); 1040-0397 (Print)}, doi = {10.1002/elan.201400076}, pages = {980 -- 987}, year = {2014}, abstract = {It is well known that biochemical and biotechnological processes are strongly dependent and affected by a variety of physico-chemical parameters such as pH value, temperature, pressure and electrolyte conductivity. Therefore, these quantities have to be monitored or controlled in order to guarantee a stable process operation, optimization and high yield. In this work, a sensor chip for the multiparameter detection of three physico-chemical parameters such as electrolyte conductivity, pH and temperature is realized using barium strontium titanate (BST) as multipurpose material. The chip integrates a capacitively coupled four-electrode electrolyte-conductivity sensor, a capacitive field-effect pH sensor and a thin-film Pt-temperature sensor. Due to the multifunctional properties of BST, it is utilized as final outermost coating layer of the processed sensor chip and serves as passivation and protection layer as well as pH-sensitive transducer material at the same time. The results of testing of the individual sensors of the developed multiparameter sensor chip are presented. In addition, a quasi-simultaneous multiparameter characterization of the sensor chip in buffer solutions with different pH value and electrolyte conductivity is performed. To study the sensor behavior and the suitability of BST as multifunctional material under harsh environmental conditions, the sensor chip was exemplarily tested in a biogas digestate.}, language = {en} } @inproceedings{ButenwegMeyerFehling2014, author = {Butenweg, Christoph and Meyer, Udo and Fehling, Ekkehard}, title = {INSYSME: first activities of the German partners}, series = {9th International Masonry Conference 2014 in Guimaraes, Portugal, 2014}, booktitle = {9th International Masonry Conference 2014 in Guimaraes, Portugal, 2014}, year = {2014}, language = {en} } @article{AkimbekovDigelZhubanova2014, author = {Akimbekov, Nuraly S. and Digel, Ilya and Zhubanova, A. A.}, title = {Advantages of creation of e-books in training of specialists biologists and biotechnologists}, series = {KazNU Bulletin. Biology series.}, volume = {60}, journal = {KazNU Bulletin. Biology series.}, number = {1}, publisher = {Al-Farabi Kazakh National University}, address = {Almaty}, issn = {1563-0218}, pages = {249 -- 252}, year = {2014}, abstract = {The necessity of e-books as a primary of learning, its opportunities for realization of competence during training biologist and biotechnologist specialists are determined. Definitions and requirements to the e-books, its advantages in comparison with traditional textbooks, and the ways of creation of e-books in the SunRav BookEditor program are considered.}, language = {ru} } @misc{AlKaidyTippkoetterUlber2014, author = {Al-Kaidy, Huschyar and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {Vorrichtung und Verfahren zur Bestimmung des Kontaktwinkels eines fl{\"u}ssigen oder mit Fl{\"u}ssigkeit gef{\"u}llten K{\"o}rpers [Offenlegungsschrift]}, publisher = {Deutsches Patent- und Markenamt}, address = {M{\"u}nchen}, pages = {13 Seiten}, year = {2014}, abstract = {Die vorliegende Erfindung betrifft eine Vorrichtung und ein Verfahren zur Bestimmung des Kontaktwinkels eines fl{\"u}ssigen oder mit Fl{\"u}ssigkeit gef{\"u}llten K{\"o}rpers. Dieser besteht aus einem Tr{\"a}ger (1) und einer damit verbundenen, in einem Winkelbereich von mehr als 0° bis maximal 90° neigbaren Ebene (8) mit einer darin ausgebildeten Abrollbahn (9) f{\"u}r den fl{\"u}ssigen oder mit Fl{\"u}ssigkeit gef{\"u}llten K{\"o}rper. An der Ebene (8) sind mehrere Sensoren (11, 12) zur Erfassung der Rolldauer des K{\"o}rpers entlang der Rollstrecke angeordnet. Erfindungsgem{\"a}ß ist vorgesehen, dass die Einstellung des Neigungswinkels der Ebene (8) {\"u}ber ein Winkelmessger{\"a}t (10) erfolgt, wodurch ein Abrollwinkel erfassbar ist, bei dem der K{\"o}rper in Bewegung ger{\"a}t. Aus der Rolldauer, der Rollstrecke und dem Abrollwinkel wird der Kontaktwinkel des K{\"o}rpers ermittelt.}, language = {de} } @article{WuBronderPoghossianetal.2014, author = {Wu, Chunsheng and Bronder, Thomas and Poghossian, Arshak and Werner, Frederik and B{\"a}cker, Matthias and Sch{\"o}ning, Michael Josef}, title = {Label-free electrical detection of DNA with a multi-spot LAPS: First step towards light-addressable DNA chips}, series = {Physica status solidi A : Applications and materials science}, volume = {211}, journal = {Physica status solidi A : Applications and materials science}, number = {6}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)}, doi = {10.1002/pssa.201330442}, pages = {1423 -- 1428}, year = {2014}, abstract = {A multi-spot (4 × 4 spots) light-addressable potentiometric sensor (MLAPS) consisting of an Al-p-Si-SiO2 structure has been applied for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge for the first time. Single-stranded probe ssDNA molecules (20 bases) were covalently immobilized onto the silanized SiO2 gate surface. The unspecific adsorption of mismatch ssDNA on the MLAPS gate surface was blocked by bovine serum albumin molecules. To reduce the screening effect and to achieve a high sensor signal, the measurements were performed in a low ionic-strength solution. The photocurrent-voltage (I-V) curves were simultaneously recorded on all 16 spots after each surface functionalization step. Large shifts of I-V curves of 25 mV were registered after the DNA immobilization and hybridization event. In contrast, a small potential shift (∼5 mV) was observed in case of mismatch ssDNA, revealing good specificity of the sensor. The obtained results demonstrate the potential of the MLAPS as promising transducer platform for the multi-spot label-free electrical detection of DNA molecules by their intrinsic molecular charge.}, language = {en} } @inproceedings{WuBronderPoghossianetal.2014, author = {Wu, Chunsheng and Bronder, Thomas and Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {DNA-hybridization detection using light-addressable potentiometric sensor modified with gold layer}, series = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)}, booktitle = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)}, publisher = {VDE-Verl.}, address = {D{\"u}sseldorf}, organization = {VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik}, isbn = {978-3-8007-3622-5}, pages = {1 -- 4}, year = {2014}, language = {en} } @inproceedings{HuckPoghossianBuniatyanetal.2014, author = {Huck, Christina and Poghossian, Arshak and Buniatyan, V. and Sch{\"o}ning, Michael Josef}, title = {Multi-parameter detection for supporting monitoring and control of biogas processes in agriculture}, series = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)}, booktitle = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)}, publisher = {VDE-Verl.}, address = {Berlin}, organization = {VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik}, isbn = {978-3-8007-3622-5}, pages = {1 -- 5}, year = {2014}, language = {en} } @inproceedings{AnthrakidisHerrmannMirzaetal.2014, author = {Anthrakidis, Anette and Herrmann, Ulf and Mirza, M. F. and Schorn, Christian and Schwarzer, Klemens and Wedding, Philipp and Weis, Fabian}, title = {Parabolrinnenentwicklung und Qualifizierung am Solar-Institut J{\"u}lich}, series = {Thermische Solarenergie : 24. Symposium ; 7. bis 9. Mai 2014, Kloster Banz, Bad Staffelstein}, booktitle = {Thermische Solarenergie : 24. Symposium ; 7. bis 9. Mai 2014, Kloster Banz, Bad Staffelstein}, publisher = {OTTI}, address = {Regensburg}, organization = {Ostbayerisches Technologie-Transfer-Institut}, isbn = {978-3-943891-35-5}, pages = {242 -- 243}, year = {2014}, language = {de} } @incollection{SchoeningPoghossianGluecketal.2014, author = {Sch{\"o}ning, Michael Josef and Poghossian, Arshak and Gl{\"u}ck, Olaf and Thust, Marion}, title = {Electrochemical methods for the determination of chemical variables in aqueous media}, series = {Measurement, instrumentation, and sensors handbook / ed. by John G. Webster [u.a.] Vol. 2 : Electromagnetic, optical, radiation, chemical, and biomedical measurement}, booktitle = {Measurement, instrumentation, and sensors handbook / ed. by John G. Webster [u.a.] Vol. 2 : Electromagnetic, optical, radiation, chemical, and biomedical measurement}, publisher = {CRC Pr.}, address = {Boca Raton, Fla.}, isbn = {978-1-4398-4891-3}, pages = {55-1 -- 55-54}, year = {2014}, language = {en} } @article{HoltrupSadeghfamHeuermannetal.2014, author = {Holtrup, S. and Sadeghfam, Arash and Heuermann, Holger and Awakowicz, P.}, title = {Characterization and optimization technique for microwave-driven high-intensity discharge lamps using hot S-parameters}, series = {IEEE transactions on microwave theories and techniques}, volume = {62}, journal = {IEEE transactions on microwave theories and techniques}, number = {10}, publisher = {IEEE}, address = {New York}, issn = {0018-9480}, doi = {10.1109/TMTT.2014.2342652}, pages = {2471 -- 2480}, year = {2014}, abstract = {High-intensity discharge lamps can be driven by radio-frequency signals in the ISM frequency band at 2.45 GHz, using a matching network to transform the impedance of the plasma to the source impedance. To achieve an optimal operating condition, a good characterization of the lamp in terms of radio frequency equivalent circuits under operating conditions is necessary, enabling the design of an efficient matching network. This paper presents the characterization technique for such lamps and presents the design of the required matching network. For the characterization, a high-intensity discharge lamp was driven by a monofrequent large signal at 2.45 GHz, whereas a frequency sweep over 300 MHz was performed across this signal to measure so-called small-signal hot S-parameters using a vector network analyzer. These parameters are then used as an equivalent load in a circuit simulator to design an appropriate matching network. Using the measured data as a black-box model in the simulation results in a quick and efficient method to simulate and design efficient matching networks in spite of the complex plasma behavior. Furthermore, photometric analysis of high-intensity discharge lamps are carried out, comparing microwave operation to conventional operation.}, language = {en} } @incollection{Laack2014, author = {Laack, Walter van}, title = {Zu neuen wissenschaftlichen Erkenntnissen zur Vereinbarkeit von Vernunft und Glaube}, series = {Ethik und Moral in Staat, Wirtschaft und Gesellschaft : 5. Rotary-Tag, 14.-15.2.2014, Kleve}, booktitle = {Ethik und Moral in Staat, Wirtschaft und Gesellschaft : 5. Rotary-Tag, 14.-15.2.2014, Kleve}, publisher = {Edition Virgines}, address = {Lingen}, organization = {Rotary-Tag <5, 2014, Kleve>}, isbn = {978-3-944011-21-9}, pages = {152 -- 162}, year = {2014}, language = {de} } @article{Laack2014, author = {Laack, Walter van}, title = {Therefore Fermat is right}, series = {American journal of humanities and social sciences : AJHSS}, volume = {2}, journal = {American journal of humanities and social sciences : AJHSS}, number = {2}, issn = {2329-079X (E-Journal); 2329-0781 (Print)}, pages = {117 -- 120}, year = {2014}, abstract = {It was Fernat's idea to investigate how many numbers would fulfill the equation according to the Pythagorean Theorem if the exponent were increased to random, e.g. to a3 + b3 = c3. His question became therefore: are there two whole numbers the cubes of which add up to the volume of the cube of a third whole number? He posed this same question, of course, for all kinds of higher exponents, so that the equation could be generalized: is there an integral solution for the equation an + bn = cn, if the exponent n is higher than 2? Although in 1993, the English mathematician Andrew Wiles was able to produce an arithmetical proof for Fermat's famous theorem, I will show that there is a simple logical explanation which is also pragmatic and plausible and what is the result of a fundamental alternative idea how our world seems to be constructed.}, language = {en} } @incollection{SchoeningPoghossianGluecketal.2014, author = {Sch{\"o}ning, Michael Josef and Poghossian, Arshak and Gl{\"u}ck, Olaf and Thust, Marion}, title = {Electrochemical composition measurement}, series = {Measurement, instrumentation, and sensors handbook: electromagnetic, optical, radiation, chemical, and biomedical measuremen}, booktitle = {Measurement, instrumentation, and sensors handbook: electromagnetic, optical, radiation, chemical, and biomedical measuremen}, edition = {2nd ed.}, publisher = {CRC Pr.}, address = {Boca Raton, Fa.}, isbn = {978-1-4398-4891-3}, pages = {55-1 -- 55-54}, year = {2014}, language = {en} } @article{Laack2014, author = {Laack, Walter van}, title = {Nature is much smarter than expected: the Genetic Code is not degenerate}, series = {American journal of humanities and social sciences}, volume = {Vol. 2}, journal = {American journal of humanities and social sciences}, number = {No. 1}, issn = {2329-0781 (Print) ; 2329-079X (Online)}, pages = {10 -- 12}, year = {2014}, abstract = {In any books about genetics it can still today be read that our genetic code is called "degenerate" because it is still believed that 43 = 64 triplets encode the 20 essential amino acids. Indeed we have to assume the inverse law, what means that 34 = 81 exact code positions are really effective for our genetic code and encode the amino acids, compiled to proteins. This very important discovery leads to two completely new results that are limits-overlooking: 1) 34 (=81) genetic code positions mean exactly the same number as there are stable and naturally existing chemical elements in our universe. This famous argument should now lead to some alternative, as well as new fundamental conclusions about our existence. 2) A genetic code positioning system shows that nature is much smarter than expected: mutations are made less dangerous than believed, because they won't be that easily able any more to cause severe damages in the protein-synthesis. This should also lead to some alternative views upon evolution of life.}, language = {en} } @misc{Ritz2014, author = {Ritz, Thomas}, title = {Multiplattformentwicklung f{\"u}r mobile Informationssysteme : eine strategische Perspektive ; [Vortragsfolien]}, series = {Info-Veranstaltung Multiplattform-Entwicklung f{\"u}r mobile Entwicklungen, Dezember 2013}, journal = {Info-Veranstaltung Multiplattform-Entwicklung f{\"u}r mobile Entwicklungen, Dezember 2013}, organization = {eBusinessLotse, Infob{\"u}ro f{\"u}r Unternehmen, Aachen}, pages = {13 S. : Ill., graph. Darst.}, year = {2014}, language = {de} } @article{BeckBuchleitnerFerreinetal.2014, author = {Beck, Daniel and Buchleitner, Martin and Ferrein, Alexander and Niem{\"u}ller, Tim and Steinbauer, Gerald}, title = {Mostly Harmless \& AllemaniACs - mixed innovations}, pages = {1 -- 8}, year = {2014}, language = {en} } @techreport{RitzSiekmannWallenborn2014, author = {Ritz, Thomas and Siekmann, Kirsten and Wallenborn, Ramona}, title = {3D-Druck - Prozessmanagement f{\"u}r individualisierte Massenprodukte : Wie k{\"o}nnen Fertigungsdienstleister in die endkundengerichtete Produktion integriert werden? ; Info-Brosch{\"u}re}, publisher = {eBusiness-Lotse}, address = {Aachen}, pages = {16 S. : Ill., graph. Darst.}, year = {2014}, abstract = {Die Informationsbrosch{\"u}re „3D-Druck - Prozessmanagement f{\"u}r individualisierte Massenprodukte" richtet sich an 3D-Druckdienstleister, die additive Fertigungsverfahren (Additive Manufacturing) nutzen, sowie an IT-Dienstleister, die eine Plattform f{\"u}r den Datenaustausch und die Individualisierung anbieten. Mit der additiven 3D-Drucktechnologie erfolgt die Fertigung von Produkten durch einen schichtweisen Aufbau. In dieser Brosch{\"u}re werden m{\"o}gliche Potenziale im Bereich der Herstellung mittels additiver Fertigungsverfahren aufgezeigt.}, language = {de} } @misc{TippkoetterDuweRaisetal.2014, author = {Tippk{\"o}tter, Nils and Duwe, Anna and Rais, Dominik and Zibek, Susanne and Zorn, H.}, title = {Optimierung und Scale-up der enzymatischen Hydrolyse inkl. Ligninabbau}, series = {Chemie Ingenieur Technik}, volume = {86}, journal = {Chemie Ingenieur Technik}, number = {9}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201450287}, pages = {1515}, year = {2014}, abstract = {Prim{\"a}re Ziele der Hydrolyse pflanzlicher nachwachsender Rohstoffe sind m{\"o}glichst hohe Zuckerkonzentrationen f{\"u}r nachfolgende Fermentationen und eine Maximierung der Produktivit{\"a}t. Zur Optimierung dieser Prozesse wird Organosolv-aufgeschlossene Buchenholz-Cellulose verwendet. Die Hydrolyse des Faserstoffes erfolgt mithilfe von Novozymes CTec2-Enzymen. Die Hydrolysen konnten durch neue R{\"u}hrerelemente auf einen Maßstab von 1000 L {\"u}bertragen werden. Dabei konnten maximale Ausbeuten (g Glucose g -1 Glucose im Faserstoff) bis 81 g g - 1 und Konzentrationen von 152 g L -1 erreicht werden. Zurzeit k{\"o}nnen unter Einsatz eines Feststoffreaktors Cellulosefasern in einer Konzentration bis 400 g L -1 enzymatisch hydrolysiert werden. Die cellulolytischen Enzyme stoßen bei hohen Feststoffkonzentrationen an ihre Grenzen. Mit steigendem Feststoffgehalt nimmt die Hydrolyseausbeute ab. Ein Ansatz zur Steigerung der Effizienz ist der Einsatz ligninolytischer Enzyme, die Ligninreste an der Organosolv-Cellulose aufschließen k{\"o}nnen. Eine solche Verbesserung der Zug{\"a}nglichkeit f{\"u}r cellulolytische Enzyme an ihr Substrat wurde durch Kultur{\"u}berst{\"a}nde verschiedener ligninolytischer Pilze erreicht. Mit Kultur{\"u}berst{\"a}nden von Stereum sp. sind Steigerungen der Glucoseausbeuten um bis zu 30 \% m{\"o}glich.}, language = {de} } @inproceedings{BuniatyanHuckPoghossianetal.2014, author = {Buniatyan, V. V. and Huck, Christina and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Rustamyan, L. G. and Hovnikyan, H. H.}, title = {Equivalent circuit and optimization of impedance characteristics of an electrolyte conductivity sensor}, series = {Proceedings of State Engineering University Armenia : Series Information technologies, electronics, radio engineering}, volume = {Iss. 17}, booktitle = {Proceedings of State Engineering University Armenia : Series Information technologies, electronics, radio engineering}, number = {No. 1}, pages = {69 -- 76}, year = {2014}, language = {en} } @inproceedings{NiedermeierClemensKowalskietal.2014, author = {Niedermeier, H. and Clemens, J. and Kowalski, Julia and Macht, S. and Heinen, D. and Hoffmann, R. and Linder, Peter}, title = {Navigation system for a research ice probe for antarctic glaciers}, series = {IEEE/ION Position, Location and Navigation Symposium (PLANS) ; 5-8 May 2014, Monterey, Calif.}, booktitle = {IEEE/ION Position, Location and Navigation Symposium (PLANS) ; 5-8 May 2014, Monterey, Calif.}, publisher = {IEEE}, address = {Piscataway, NJ}, organization = {Position, Location and Navigation Symposium <2014, Monterey, Calif.>}, isbn = {978-1-4799-3319-8}, pages = {959 -- 975}, year = {2014}, language = {en} } @article{WolfBiesenGreeb2014, author = {Wolf, Martin R. and Biesen, Ina van der and Greeb, Birgit}, title = {Mein Freund, die Uni}, series = {Die neue Hochschule : DNH : f{\"u}r anwendungsbezogene Wissenschaft und Kunst}, volume = {2014}, journal = {Die neue Hochschule : DNH : f{\"u}r anwendungsbezogene Wissenschaft und Kunst}, number = {2}, publisher = {HLB}, address = {Bonn}, issn = {0340-448X}, pages = {54 -- 56}, year = {2014}, language = {de} } @misc{TippkoetterWiesenThieletal.2014, author = {Tippk{\"o}tter, Nils and Wiesen, S. and Thiel, A. and Muffler, K. and Ulber, Roland}, title = {Biotechnologische Wertstoffgewinnung entlang der Prozessketten Gr{\"u}ner und Pflanzen{\"o}l-Bioraffinerien}, series = {Chemie Ingenieur Technik}, volume = {86}, journal = {Chemie Ingenieur Technik}, number = {9}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201450283}, pages = {1605}, year = {2014}, abstract = {Der nachwachsende Rohstoff Raps ist in großen Mengen verf{\"u}gbar und eine Quelle f{\"u}r Biomolek{\"u}le mit hohem Wertsch{\"o}pfungspotenzial. Entwicklungen zur biotechnologischen Wertstoffgewinnung werden dabei schwerpunktm{\"a}ßig in den Bereichen Aufarbeitung und Funktionalisierung von Polyphenolen und Fetten betrieben. Bei der Verarbeitung der Pflanzenmaterialien werden dabei insbesondere Verfahren zur adsorptiven Aufreinigung und Auftrennung mittels Materialien mit modifizierten Bleicherden und anderen organischen oder anorganischen Adsorbentien untersucht. Ferner wurden f{\"u}r die Aufreinigung von Polyphenolen adsorptive sowie extraktive Prozesse entwickelt. Bei den Entwicklungen wird ber{\"u}cksichtigt, dass Bioraffinerien auf eine fortw{\"a}hrende Gew{\"a}hrleistung eines hohen Produktions- bzw. Lieferbedarfs nachwachsender Rohstoffe angewiesen sind. Somit werden Optionen dezentraler regionaler Vorbehandlungs- und Wertsch{\"o}pfungsketten in der N{\"a}he landwirtschaftlicher Betriebe einbezogen. Neben neuen Aufreinigungsverfahren werden mikrobielle und enzymatische Prozesse zur wertsteigernden Umsetzung von Glycerin, Polyphenolen und Zuckermonomeren vorgestellt sowie Limitierungen nachwachsender Rohstoffe der 2. Generation diskutiert.}, language = {de} } @inproceedings{OertelBung2014, author = {Oertel, Mario and Bung, Daniel Bernhard}, title = {Numerische Str{\"o}mungssimulation von Fließgew{\"a}ssern - Wo stehen wir und was werden wir im Laufe der n{\"a}chsten Jahre erreichen?}, series = {Simulationsverfahren und Modelle f{\"u}r Wasserbau und Wasserwirtschaft = Simulation techniques and models for hydraulic engineering and water management / 37. Dresdner Wasserbaukolloquium 2014, 13. - 14. M{\"a}rz 2014. (Dresdner wasserbauliche Mitteilungen ; H. 50)}, booktitle = {Simulationsverfahren und Modelle f{\"u}r Wasserbau und Wasserwirtschaft = Simulation techniques and models for hydraulic engineering and water management / 37. Dresdner Wasserbaukolloquium 2014, 13. - 14. M{\"a}rz 2014. (Dresdner wasserbauliche Mitteilungen ; H. 50)}, organization = {Dresdner Wasserbaukolloquium <37, 2014>}, isbn = {978-3-86780-349-6}, pages = {19 -- 30}, year = {2014}, language = {de} } @inproceedings{TranStaat2014, author = {Tran, Thanh Ngoc and Staat, Manfred}, title = {Uncertain multimode failure and limit analysis of shells}, series = {11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20-25, 2014, Barcelona}, booktitle = {11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20-25, 2014, Barcelona}, editor = {Onate, E.}, organization = {World Congress on Computational Mechanics <11, 2014, Barcelona>}, pages = {1 -- 12}, year = {2014}, language = {en} } @article{BronderWuPoghossianetal.2014, author = {Bronder, Thomas and Wu, Chunsheng and Poghossian, Arshak and Werner, Frederik and Keusgen, M. and Sch{\"o}ning, Michael Josef}, title = {Label-free detection of DNA hybridization with light-addressable potentiometric sensors: comparison of various DNA-immobilization strategies}, series = {Procedia Engineering}, volume = {87}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2014.11.647}, pages = {755 -- 758}, year = {2014}, abstract = {Light-addressable potentiometric sensors (LAPS) consisting of a p-Si-SiO2 and p-Si-SiO2-Au structure, respectively, have been tested for a label-free electrical detection of DNA (deoxyribonucleic acid) hybridization. Three different strategies for immobilizing single-stranded probe DNA (ssDNA) molecules on a LAPS surface have been studied and compared: (a) immobilization of thiol-modified ssDNA on the patterned Au surface via gold-thiol bond, (b) covalent immobilization of amino-modified ssDNA onto the SiO2 surface functionalized with 3-aminopropyltriethoxysilane and (c) layer-by-layer adsorption of negatively charged ssDNA on a positively charged weak polyelectrolyte layer of poly(allylamine hydrochloride).}, language = {en} } @inproceedings{BaeckerSchusserLeinhosetal.2014, author = {B{\"a}cker, Matthias and Schusser, Sebastian and Leinhos, Marcel and Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Sensor system for the monitoring of degradation processes of biodegradable biopolymers}, series = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)}, booktitle = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)}, publisher = {VDE-Verl.}, address = {D{\"u}sseldorf}, organization = {VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik}, isbn = {978-3-8007-3622-5}, pages = {1 -- 4}, year = {2014}, language = {en} } @article{Laack2014, author = {Laack, Walter van}, title = {Nahtoderfahrungen aus medizinischer Sicht}, series = {Deutsche medizinische Wochenschrift : DMW}, volume = {Jg. 139}, journal = {Deutsche medizinische Wochenschrift : DMW}, number = {H. 51/52}, publisher = {Thieme}, address = {Stuttgart}, issn = {1439-4413 (E-Journal); 0012-0472 (Print); 1437-5982 (Print)}, doi = {10.1055/s-0034-1387363}, pages = {2651 -- 2654}, year = {2014}, abstract = {Nah- versus Nachtoderfahrungen Nahtoderfahrungen (NTE) sind ein Ph{\"a}nomen aus der Kategorie „außergew{\"o}hnliche Bewusstseinserfahrungen". Sie treten in unmittelbarer N{\"a}he des eigenen Todes auf. Oft, aber nicht immer, handelt es sich dabei um Erfahrungen von Personen, die durch {\"a}rztliche Maßnahmen wiederbelebt wurden und sp{\"a}ter davon berichten (NTE-ler). Jedoch kommen solche Ph{\"a}nomene auch bei Menschen vor, die w{\"a}hrend einer schweren Erkrankung eine lebensbedrohliche Krise haben, hiervon aber spontan genesen. Den NTE {\"a}hnlich sind auch sogenannte Nachtod-erfahrungen sowie spontane Erlebnisse, die im Rahmen anderer außergew{\"o}hnlicher Stresssituationen auftreten. Von Nachtoderfahrungen spricht man, wenn die Betroffenen anl{\"a}sslich des Todes von geliebten Angeh{\"o}rigen oder Freunden Erlebnisse haben, die inhaltlich ebenfalls, zumindest aber teilweise, denen von NTE entsprechen. Nachtoderfahrungen sowie spontane NTE-{\"a}hnliche Erlebnisse unterscheiden sich jedoch von den echten NTE zumeist sowohl quantitativ als auch qualitativ. Unter einem quantitativen Unterschied versteht man in diesem Zusammenhang eine in der Regel geringer ausgepr{\"a}gte Komplexit{\"a}t, als sie sehr vielen NTE zu eigen ist. Da sich aber auch viele NTE selbst bez{\"u}glich ihrer Komplexit{\"a}t unterscheiden, ist der Hauptunterschied qualitativer Natur: Echte NTE besitzen gegen{\"u}ber den anderen hier erw{\"a}hnten Ph{\"a}nomenen eine gr{\"o}ßere inhaltliche und emotionale Tiefe. Sie begleiten die Betroffenen anschließend ein Leben lang - zumeist mit positiven, in Einzelf{\"a}llen aber auch mit negativen Folgen, die bis zu einem sp{\"a}teren Suizid reichen k{\"o}nnen. Die genannten außergew{\"o}hnlichen Bewusstseinsph{\"a}nomene lassen sich in ihrer Gesamtheit bei rund 5 \% der Bev{\"o}lkerung finden. NTE im Speziellen haben hiervon einen durchaus bedeutenden Anteil. Je nach Studie geben zwischen 18 \% und 40 \% aller Personen, die reanimiert wurden, an, w{\"a}hrenddessen eine NTE erlebt zu haben. Dass nicht alle eine solche Erfahrung machen, wird von Kritikern gern dahingehend interpretiert, NTE seien rein physiologischer und keineswegs spiritueller Natur. Jedoch sollte man bedenken, dass im Fall einer rein neurophysiologischen Grundlage von NTE dann bei jedem ein solches Ph{\"a}nomen zu erwarten w{\"a}re, so wie beispielsweise auch die Symptome einer Hypoglyk{\"a}mie im Wesentlichen immer dieselben sind.}, language = {de} } @article{RauAlexopoulosBreitbachetal.2014, author = {Rau, Christoph and Alexopoulos, Spiros and Breitbach, Gerd and Hoffschmidt, Bernhard and Latzke, Markus and Sattler, Johannes Christoph}, title = {Transient simulation of a solar-hybrid tower power plant with open volumetric receiver at the location Barstow}, series = {Energy procedia : proceedings of the SolarPACES 2013 International Conference}, volume = {49}, journal = {Energy procedia : proceedings of the SolarPACES 2013 International Conference}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1876-6102}, doi = {10.1016/j.egypro.2014.03.157}, pages = {1481 -- 1490}, year = {2014}, abstract = {In this work the transient simulations of four hybrid solar tower power plant concepts with open-volumetric receiver technology for a location in Barstow-Daggett, USA, are presented. The open-volumetric receiver uses ambient air as heat transfer fluid and the hybridization is realized with a gas turbine. The Rankine cycle is heated by solar-heated air and/or by the gas turbine's flue gases. The plant can be operated in solar-only, hybrid parallel or combined cycle-only mode as well as in any intermediate load levels where the solar portion can vary between 0 to 100\%. The simulated plant is based on the configuration of a solar-hybrid power tower project, which is in planning for a site in Northern Algeria. The meteorological data for Barstow-Daggett was taken from the software meteonorm. The solar power tower simulation tool has been developed in the simulation environment MATLAB/Simulink and is validated.}, language = {en} } @misc{Ritz2014, author = {Ritz, Thomas}, title = {Multiplattformentwicklung f{\"u}r mobile Informationssysteme : eine strategische Perspektive}, series = {Info-Veranstaltung Multiplattform-Entwicklung f{\"u}r mobile Anwendungen, Dezember 2013}, journal = {Info-Veranstaltung Multiplattform-Entwicklung f{\"u}r mobile Anwendungen, Dezember 2013}, organization = {FH Aachen, University of Applied Sciences / m2clab}, pages = {1 Video (Laufzeit: 23:57 Min.)}, year = {2014}, language = {de} } @inproceedings{GebhardtRitzSiekmannetal.2014, author = {Gebhardt, Andreas and Ritz, Thomas and Siekmann, Kirsten and Wallenborn, Ramona}, title = {Additive manufacturing businesses in the process chain of individualized mass products}, series = {DDMC 2014 : Proceedings of the Fraunhofer Direct Digital Manufacturing Conference}, booktitle = {DDMC 2014 : Proceedings of the Fraunhofer Direct Digital Manufacturing Conference}, editor = {Demmer, Axel}, publisher = {Fraunhofer}, address = {Stuttgart}, isbn = {978-3-8396-9128-1 (E-Book)}, year = {2014}, language = {en} } @misc{DuweSiekerTippkoetteretal.2014, author = {Duwe, A. and Sieker, T. and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {Grasssilage als Substrat zur fermentativen Produktion organischer S{\"a}uren}, series = {Chemie Ingenieur Technik}, volume = {86}, journal = {Chemie Ingenieur Technik}, number = {9}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201450345}, pages = {1400}, year = {2014}, abstract = {Der zunehmende Bedarf an fossilen Rohstoffen bei gleichzeitig abnehmender Versorgungssicherheit f{\"u}hrt zu einer intensiven Suche nach erneuerbaren Ressourcen. Ein vielversprechendes Ausgangsmaterial mit einer weltweiten Verf{\"u}gbarkeit stellt Gras dar. In 2012 wurden in Deutschland 33 Millionen Tonnen (Heugewicht) Gras auf 4,82 Millionen Hektar Ackerland produziert, davon wurden 60,5 \% siliert. Durch die Silierung kann Gras als Substrat zeitlich uneingeschr{\"a}nkt verf{\"u}gbar sein, ohne dem Risiko des schnellen Verderbs ausgesetzt zu sein. Eine Schl{\"u}sselrolle im Rahmen des Silierprozesses nimmt die Produktion von Milchs{\"a}ure ein. Milchs{\"a}ure ist einbedeutendes biotechnologisches Produkt f{\"u}r die Lebensmittel- und die chemische Industrie. Im Rahmen dieser Arbeit wird die vollst{\"a}ndige Umwandlung der fermentierbaren Zucker in der Silage zu Milchs{\"a}ure angestrebt, um die maximale Ausbeute der organischen S{\"a}ure zu erreichen. Im ersten Verfahrensschritt wird die Silage gepresst und der erhaltene Presskuchen einer Liquid-Hot-Water-Behandlung unterzogen. Durch diese einfache Vorbehandlung k{\"o}nnen hohe Glucoseausbeuten im nachfolgenden SSF-Schritt bei gleichzeitig geringem Enzymeinsatz und Chemikalienverbrauch realisiert werden. Zur Aufreinigung der Milchs{\"a}ure wurden extraktive und chromatographische Methoden untersucht.}, language = {de} } @article{BaeckerSchusserPoghossianetal.2014, author = {B{\"a}cker, Matthias and Schusser, Sebastian and Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Multi-Parametererfassung mit siliziumbasiertem Sensorchip: Aus Drei mach Eins}, series = {GIT Labor-Fachzeitschrift}, journal = {GIT Labor-Fachzeitschrift}, number = {2}, publisher = {Wiley}, issn = {0016-3538}, pages = {28 -- 30}, year = {2014}, language = {de} } @incollection{PoghossianWeilandSchoening2014, author = {Poghossian, Arshak and Weiland, Maryam and Sch{\"o}ning, Michael Josef}, title = {Nanoplate field-effect capacitors: a new transducer structure for multiparameter (bio-)chemical sensing}, series = {Multisensor system for chemical analysis : materials and sensors}, booktitle = {Multisensor system for chemical analysis : materials and sensors}, editor = {Lvova, Larisa and Kirsanov, Dmitry and di Natale, Corrado and Legin, Audrey}, edition = {1}, publisher = {Jenny Stanford Publishing}, address = {Singapore}, isbn = {978-981-4411-15-8 ; 978-981-4411-16-5}, doi = {10.1201/b15491-11}, pages = {333 -- 373}, year = {2014}, abstract = {An array of electrically isolated nanoplate field-effect silicon-on-insulator (SOI) capacitors as a new transducer structure for multiparameter (bio-)chemical sensing is presented. The proposed approach allows addressable biasing and electrical readout of multiple nanoplate field-effect capacitive (bio-)chemical sensors on the same SOI chip, as well as differential-mode measurements. The realized sensor chip has been applied for pH and penicillin concentration measurements, electrical monitoring of polyelectrolyte multilayer formation, and the label-free electrical detection of consecutive deoxyribonucleic acid (DNA) hybridization and denaturation events.}, language = {en} } @inproceedings{FuchsRitz2014, author = {Fuchs, Britta and Ritz, Thomas}, title = {Usability for Blended Shopping - Solving Major Flaws by Applying Usability Engineering and Proven Integration Technologies}, series = {Proceedings of the 11th International Conference on e-Business, ICE-B 2014, Vienna, Austria}, booktitle = {Proceedings of the 11th International Conference on e-Business, ICE-B 2014, Vienna, Austria}, isbn = {978-989-758-043-7}, doi = {10.5220/0005113502160223}, pages = {216 -- 223}, year = {2014}, language = {en} } @article{WiesenTippkoetterMuffleretal.2014, author = {Wiesen, Sebastian and Tippk{\"o}tter, Nils and Muffler, Kai and Suck, Kirstin and Sohling, Ulrich and Ruf, Nils and Ulber, Roland}, title = {Adsorptive Vorbehandlung von Rohglycerin f{\"u}r die 1,3-Propandiol Fermentation mit Clostridium diolis}, series = {Chemie Ingenieur Technik}, volume = {86}, journal = {Chemie Ingenieur Technik}, number = {1-2}, publisher = {Wiley-VCH}, address = {Weinheim}, doi = {10.1002/cite.201300080}, pages = {129 -- 135}, year = {2014}, abstract = {Bei der Gewinnung von Fetts{\"a}uren aus Pflanzen{\"o}len, z. B. zur Herstellung von Biopolymeren, oder bei der Biodiesel- und Seifenproduktion, f{\"a}llt Glycerin als Nebenprodukt an. Bei der Biokonversion dieses Rohstoffes zu 1,3-Propandiol wird der Produktionsorganismus Clostridium diolis durch Verunreinigungen im Rohglycerin gehemmt. Als inhibierende Substanzen konnten freie Fetts{\"a}uren identifiziert werden. Mithilfe eines adsorptiven Aufarbeitungsverfahrens ist es gelungen, die Fetts{\"a}uren zu entfernen und die Konversionseffizienz zu 1,3-Propandiol zu erh{\"o}hen.}, language = {de} } @article{AlKaidyDuweHusteretal.2014, author = {Al-Kaidy, Huschyar and Duwe, Anna and Huster, Manuel and Muffler, Kai and Schlegel, Christin and Sieker, Tim and Stadtm{\"u}ller, Ralf and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {Biotechnologie und Bioverfahrenstechnik - Vom ersten Ullmanns Artikel bis hin zu aktuellen Forschungsthemen}, series = {Chemie Ingenieur Technik}, volume = {86}, journal = {Chemie Ingenieur Technik}, number = {12}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201400083}, pages = {2215 -- 2225}, year = {2014}, abstract = {Biotechnologie und die mit ihr verbundenen technischen Prozesse pr{\"a}gen seit Jahrtausenden die Entwicklung der Menschheit. Ausgehend von empirischen Verfahren, insbesondere zur Herstellung von Lebensmitteln und t{\"a}glichen Gebrauchsg{\"u}tern, haben sich diese Disziplinen zu einem der innovativsten Zukunftsfelder entwickelt. Durch das immer detailliertere Verst{\"a}ndnis zellul{\"a}rer Vorg{\"a}nge k{\"o}nnen mittlerweile Produktionsst{\"a}mme gezielt optimiert werden. Im Zusammenspiel mit moderner Prozesstechnik k{\"o}nnen so eine Vielzahl von Bulk- und Feinchemikalien sowie Pharmazeutika effizient hergestellt werden. In diesem Artikel werden exemplarisch einige der aktuellen Trends vorgestellt.}, language = {de} } @article{PasteurTippkoetterKampeisetal.2014, author = {Pasteur, Aline and Tippk{\"o}tter, Nils and Kampeis, Percy and Ulber, Roland}, title = {Optimization of high gradient magnetic separation filter units for the purification of fermentation products}, series = {IEEE TRANSACTIONS ON MAGNETICS}, volume = {50}, journal = {IEEE TRANSACTIONS ON MAGNETICS}, number = {10}, publisher = {IEEE}, address = {New York, NY}, issn = {0018-9464}, doi = {10.1109/TMAG.2014.2325535}, pages = {Artikel 5000607}, year = {2014}, abstract = {High gradient magnetic separation (HGMS) has been established since the early 1970s. A more recent application of these systems is the use in bioprocesses. To integrate the HGMS in a fermentation process, it is necessary to optimize the separation matrix with regard to the magnetic separation characteristics and permeability of the non-magnetizable components of the fermentation broth. As part of the work presented here, a combined fluidic and magnetic force finite element model simulation was created using the software COMSOL Multiphysics and compared with separation experiments. Finally, as optimal lattice orientation of the separation matrix, a transversal rhombohedral arrangement was defined. The high suitability of the new filter matrix has been verified by separation experiments.}, language = {en} } @misc{TippkoetterRothMoehringetal.2014, author = {Tippk{\"o}tter, Nils and Roth, J. and M{\"o}hring, M. and Wulfhorst, H. and Ulber, Roland}, title = {Verwertung von Bioraffinerie-Stoffstr{\"o}men am Beispiel von Einzellerproteinen}, series = {Chemie Ingenieur Technik}, volume = {86}, journal = {Chemie Ingenieur Technik}, number = {9}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201450257}, pages = {1399 -- 1400}, year = {2014}, abstract = {Die Nutzung von Biomasse aus pflanzlichen Abf{\"a}llen f{\"u}r die stoffliche Verwertung r{\"u}ckt immer st{\"a}rker in den Vordergrund. Dabei ist vor allem die ganzheitliche Verwertung der Stoffstr{\"o}me von Bedeutung, da diese einen integrativen Ansatz erm{\"o}glichen. Im Rahmen dieser Arbeit wird die Produktion von Einzellerproteinen (Single-Cell Proteins, SCPs) mithilfe von unterschiedlichen Rohsubstraten dargelegt. Somit k{\"o}nnen Reststoffstr{\"o}me, die in keiner Konkurrenz zur Produktion von Lebensmitteln stehen, f{\"u}r die Herstellung von Futter- und auch Nahrungsmitteln Verwendung finden. Die zun{\"a}chst thermisch vorbehandelten Ausgangsmaterialien stammen aus forstwirtschaftlichen und gr{\"u}nen Abf{\"a}llen und erm{\"o}glichen durch eine anschließende enzymatische Hydrolyse die Freisetzung von Monosacchariden. Aus diesen erfolgt die SCP-Produktion fermentativ mithilfe der drei Modellorganismen Bakterium, Hefe und Pilz. Hierf{\"u}r wird sowohl das fl{\"u}ssige Hydrolysat als auch der feste Reststoff auf der Basis einer Feststofffermentation genutzt. Auf diese Weise ist eine vollst{\"a}ndige Verwertung der Ausgangsmaterialien m{\"o}glich. Mit den gewonnen Daten erfolgt abschließend eine Bewertung der SCPs aus nachwachsenden Rohstoffen als alternative Proteinquelle.}, language = {de} } @misc{TippkoetterMoehring2014, author = {Tippk{\"o}tter, Nils and M{\"o}hring, S.}, title = {Nutzung von F{\"a}ulepilzen f{\"u}r die selektive Gewinnung von Cellulose und Lignin aus nicht vorbehandelter lignocellulosehaltiger Biomasse}, series = {Chemie Ingenieur Technik}, volume = {86}, journal = {Chemie Ingenieur Technik}, number = {9}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201450353}, pages = {1385}, year = {2014}, abstract = {Einige Arten der Braun- und Weißf{\"a}ulepilze sind in der Lage, selektiv entweder Lignin oder Cellulose im Holz abzubauen. Diese Pilze k{\"o}nnen f{\"u}r eine energiesparende Vorbehandlung lignocellulosehaltiger Biomasse f{\"u}r Bioraffinerien genutzt werden, ohne auf technisch aufw{\"a}ndige Aufschlussapparate zur{\"u}ckgreifen zu m{\"u}ssen. Weißf{\"a}ulepilze bauen bevorzugt Lignin ab, wodurch die verbleibende Cellulose leichter f{\"u}r enzymatische Hydrolysen in das Monosaccharid Glucose zug{\"a}nglich wird. Braunf{\"a}ulepilze bauen dagegen Cellulose und Hemicellulose ab. Die Auswirkungen der Behandlung von Weizenstroh mit verschiedenen Pilzarten werden zurzeit untersucht. Dabei werden die Ver{\"a}nderung der enzymatischen Hydrolysierbarkeit des Substrats sowie die gebildeten Ligninderivate bestimmt. Detaillierte Betrachtungen der Biomassever{\"a}nderung werden mithilfe spezifischer F{\"a}rbemethoden durchgef{\"u}hrt, durch die morphologische Ver{\"a}nderungen der Pflanzengewebe in der 3D-Lichtmikroskopie dargestellt werden k{\"o}nnen.}, language = {de} } @incollection{AlhwarinFerreinScholl2014, author = {Alhwarin, Faraj and Ferrein, Alexander and Scholl, Ingrid}, title = {IR stereo kinect: improving depth images by combining structured light with IR stereo}, series = {PRICAI 2014: Trends in artificial intelligence : 13th Pacific Rim International Conference on Artificial Intelligence : Gold Coast, QLD, Australia, December 1-5, 2014 : proceedings. (Lecture notes in computer science ; vol. 8862)}, booktitle = {PRICAI 2014: Trends in artificial intelligence : 13th Pacific Rim International Conference on Artificial Intelligence : Gold Coast, QLD, Australia, December 1-5, 2014 : proceedings. (Lecture notes in computer science ; vol. 8862)}, publisher = {Springer}, address = {M{\"u}nchen}, isbn = {978-3-319-13559-5 (Print) ; 978-3-319-13560-1 (E-Book)}, doi = {10.1007/978-3-319-13560-1_33}, pages = {409 -- 421}, year = {2014}, abstract = {RGB-D sensors such as the Microsoft Kinect or the Asus Xtion are inexpensive 3D sensors. A depth image is computed by calculating the distortion of a known infrared light (IR) pattern which is projected into the scene. While these sensors are great devices they have some limitations. The distance they can measure is limited and they suffer from reflection problems on transparent, shiny, or very matte and absorbing objects. If more than one RGB-D camera is used the IR patterns interfere with each other. This results in a massive loss of depth information. In this paper, we present a simple and powerful method to overcome these problems. We propose a stereo RGB-D camera system which uses the pros of RGB-D cameras and combine them with the pros of stereo camera systems. The idea is to utilize the IR images of each two sensors as a stereo pair to generate a depth map. The IR patterns emitted by IR projectors are exploited here to enhance the dense stereo matching even if the observed objects or surfaces are texture-less or transparent. The resulting disparity map is then fused with the depth map offered by the RGB-D sensor to fill the regions and the holes that appear because of interference, or due to transparent or reflective objects. Our results show that the density of depth information is increased especially for transparent, shiny or matte objects.}, language = {en} } @inproceedings{HeuermannFinger2014, author = {Heuermann, Holger and Finger, Torsten}, title = {2.45 GHz Plasma Powered Spark Plug by Thermal and EM-Optimization}, pages = {30 Folien}, year = {2014}, language = {en} } @article{Stulpe2014, author = {Stulpe, Werner}, title = {From the attempt of certain classical reformulations of quantum mechanics to quasi-probability representations}, series = {Journal of Mathematical Physics}, volume = {55}, journal = {Journal of Mathematical Physics}, number = {1}, publisher = {AIP Publishing}, address = {College Park, Md.}, issn = {222-488}, doi = {10.1063/1.4861939}, pages = {Artikel 012109}, year = {2014}, abstract = {The concept of an injective affine embedding of the quantum states into a set of classical states, i.e., into the set of the probability measures on some measurable space, as well as its relation to statistically complete observables is revisited, and its limitation in view of a classical reformulation of the statistical scheme of quantum mechanics is discussed. In particular, on the basis of a theorem concerning a non-denseness property of a set of coexistent effects, it is shown that an injective classical embedding of the quantum states cannot be supplemented by an at least approximate classical description of the quantum mechanical effects. As an alternative approach, the concept of quasi-probability representations of quantum mechanics is considered.}, language = {en} }