@article{BiselliThoemmesKulaetal.1994, author = {Biselli, Manfred and Th{\"o}mmes, J. and Kula, M.-R. and Wandrey, Christian}, title = {Batch kinetic data of hybridoma growth and productivity as a basis for the simulation of antibody production in various culture systems / Th{\"o}mmes, J. ; Biselli, M. ; Kula, M.-R. ; Wandrey, C.}, series = {Animal cell technology : products of today, prospects for tomorrow ; ESACT, European Society for Animal Cell Technology, the 12th meeting / Ed. R. E. Spier}, journal = {Animal cell technology : products of today, prospects for tomorrow ; ESACT, European Society for Animal Cell Technology, the 12th meeting / Ed. R. E. Spier}, publisher = {Butterworth-Heinemann}, address = {Oxford}, isbn = {0750618450}, pages = {513 -- 517}, year = {1994}, language = {en} } @article{BiselliVanderPolDeGooijeretal.1996, author = {Biselli, Manfred and Van der Pol, Jens J. and De Gooijer, Cornelis D. and Wandrey, Christian}, title = {Automation of selective assays for on-line bioprocess monitoring by flow-injection analysis / van der Pol, Jens J. ; de Gooijer, Cornelis D. ; Biselli, Manfred ; Wandrey, Christian ; Tramper, Johannes}, series = {Trends in Biotechnology. 14 (1996), H. 12}, journal = {Trends in Biotechnology. 14 (1996), H. 12}, isbn = {0167-7799}, pages = {471 -- 477}, year = {1996}, language = {en} } @article{BiselliVanderPolJokschetal.1992, author = {Biselli, Manfred and Van der Pol, Jens J. and Joksch, B. and Eberhardt, R.}, title = {Development of an enzymatic multichannel flow injection analysis system for monitoring mammalian cell fermentations / Van der Pol, J.J.; Joksch, B.; Eberhardt, R.; Biselli, M.; Wandrey, C., Tramper, J.}, series = {Biosensors : fundamentals, technologies and applications ; contributions to the BMFT status seminar with international participation May, 12 to 14, 1991, Internationales Bildungs-Centrum Bogensee/Brandenburg, Germany / org. by ZIM-Zentralinstitut f{\"u}r Molekularbiologie, Berlin-Buch and GBF, Braunschweig. Ed. by F. Scheller}, journal = {Biosensors : fundamentals, technologies and applications ; contributions to the BMFT status seminar with international participation May, 12 to 14, 1991, Internationales Bildungs-Centrum Bogensee/Brandenburg, Germany / org. by ZIM-Zentralinstitut f{\"u}r Molekularbiologie, Berlin-Buch and GBF, Braunschweig. Ed. by F. Scheller}, publisher = {VCH}, address = {Weinheim}, isbn = {3527284370}, pages = {349 -- 352}, year = {1992}, language = {en} } @article{BiselliVanderPolJokschetal.1994, author = {Biselli, Manfred and Van der Pol, Jens J. and Joksch, B. and Spohn, U.}, title = {On-line monitoring and control of glucose, glutamine, lactate and ammonium during a high-cell-density cultivation of hybridoma cells / van der Pol, Jens J. ; Joksch, B. ; Spohn, U. ; Biselli, M. ; Wandrey, C.}, series = {Proceedings of the sixth international meeting of the Japanese Association for Animal Cell Technology [JAACT 93]: Nagoya, Japan, November 9 - 12, 1993 / ed. by T. Kobayashi}, journal = {Proceedings of the sixth international meeting of the Japanese Association for Animal Cell Technology [JAACT 93]: Nagoya, Japan, November 9 - 12, 1993 / ed. by T. Kobayashi}, publisher = {Springer Netherland}, address = {Berlin}, isbn = {0-7923-3156-7}, pages = {167 -- 170}, year = {1994}, language = {en} } @article{BiselliVanderPolJokschetal.1995, author = {Biselli, Manfred and Van der Pol, Jens J. and Joksch, Burkhard and Galgens, Jochem}, title = {On-line control of an immobilized hybridoma culture with multi-channel flow injektion analysis / Jens J. van der Pol, Burkhard Joksch, Jochem Galgens, Manfred Biselli, Cornelis D. de Gooijer, Johannes Tramper and Christian Wandrey}, series = {Journal of Biotechnology. 43 (1995), H. 3}, journal = {Journal of Biotechnology. 43 (1995), H. 3}, isbn = {0168-1656}, pages = {229 -- 242}, year = {1995}, language = {en} } @article{BiselliVanderPolMachniketal.1997, author = {Biselli, Manfred and Van der Pol, Jens J. and Machnik, Marc and Portela-Klein, Theresa}, title = {On-line immunoanalysis of monoclonal antibodies during a continuous culture of hybridoma cells / Jens J. van der Pol, Marc Machnik, Manfred Biselli, Theresa Portela-Klein, Cornelis D. de Gooijer, Johannes Tramper und Christian Wandrey}, series = {Cytotechnology. 24 (1997), H. 1}, journal = {Cytotechnology. 24 (1997), H. 1}, isbn = {0920-9069}, pages = {19 -- 30}, year = {1997}, language = {en} } @article{BiselliVanderPolSpohnetal.1994, author = {Biselli, Manfred and Van der Pol, Jens J. and Spohn, Uwe and Eberhardt, Rolf}, title = {On-line monitoring of an animal cell culture with multi-channel flow injection analysis / van der Pol, Jens J.; Spohn, Uwe ; Eberhardt, Rolf ; G{\"a}tgens, Jochen ; Biselli, Manfred ; Wandrey, Christian ; Tramper, Johannes}, series = {Journal of Biotechnology. 37 (1994), H. 3}, journal = {Journal of Biotechnology. 37 (1994), H. 3}, isbn = {0168-1656}, pages = {253 -- 264}, year = {1994}, language = {en} } @article{BiselliWandrey1988, author = {Biselli, Manfred and Wandrey, Christian}, title = {Reaction Mechanism of an Endoglucanase of Trichoderma Reesei QM 9414 using Cellodextrins as Substrate}, series = {Technology of biological processes, safety in biotechnology, applied genetic engineering : lectures held at the 5th DECHEMA Annual Meeting of Biotechnologists, May 12 - 13, 1987, [Frankfurt, Main] / [hrsg. von Dieter Behrens ...]}, journal = {Technology of biological processes, safety in biotechnology, applied genetic engineering : lectures held at the 5th DECHEMA Annual Meeting of Biotechnologists, May 12 - 13, 1987, [Frankfurt, Main] / [hrsg. von Dieter Behrens ...]}, publisher = {VCH}, address = {Weinheim}, pages = {425 -- 429}, year = {1988}, language = {en} } @article{BiselliZengDinteretal.1997, author = {Biselli, Manfred and Zeng, Steffen and Dinter, Andre and Eisenkr{\"a}tzer, Detlef}, title = {Pilot Scale Expression and Purification of Soluble Protein A Tagged \&\#946;1,6N-Acetylglucosaminyltransferase in CHO Cells / Zeng, Steffen ; Dinter, Andre ; Eisenkr{\"a}tzer, Detlef ; Biselli, Manfred ; Wandrey, Christian ; Berger, Eric G.}, series = {Biochemical and Biophysical Research Communications. 237 (1997), H. 3}, journal = {Biochemical and Biophysical Research Communications. 237 (1997), H. 3}, isbn = {0006-291X}, pages = {653 -- 658}, year = {1997}, language = {en} } @article{BodeBartschBoulikasetal.1998, author = {Bode, J. and Bartsch, J. and Boulikas, T. and Iber, M. and Mielke, C. and Sch{\"u}beler, D. and Seibler, Jost and Benham, C.}, title = {Transcription-promoting genomic sites in mammalia: their elucidation and architectural principles}, series = {Gene therapy \& molecular biology}, volume = {1}, journal = {Gene therapy \& molecular biology}, number = {1}, issn = {1529-9120}, pages = {1 -- 29}, year = {1998}, language = {en} } @article{BodeSchlakeIberetal.2000, author = {Bode, J{\"u}rgen and Schlake, Thomas and Iber, Michaela and Sch{\"u}beler, Dirk and Seibler, Jost and Snezhkov, Evgeney and Nikolaev, Lev}, title = {The transgeneticist's toolbox: novel methods for the targeted modification of eukaryotic genomes}, series = {Biological Chemistry}, volume = {381}, journal = {Biological Chemistry}, number = {9-10}, issn = {1431-6730}, doi = {10.1515/BC.2000.103}, pages = {801 -- 813}, year = {2000}, language = {en} } @article{BongaertsBovenbergKraemeretal.2002, author = {Bongaerts, Johannes and Bovenberg, Roel and Kr{\"a}mer, Marco and M{\"u}ller, Ulrike and Raeven, Leon and Wubbolts, Marcel}, title = {Metabolic engineering to produce fine chemicals in Escherichia coli}, series = {Chemie - Ingenieur - Technik (CIT)}, volume = {Vol. 74}, journal = {Chemie - Ingenieur - Technik (CIT)}, number = {Iss. 5}, issn = {1522-2640 (E-Journal); 0009-286X (Print)}, pages = {694}, year = {2002}, language = {en} } @article{BongaertsEsserLorbachetal.2011, author = {Bongaerts, Johannes and Esser, Simon and Lorbach, Volker and Al-Momani, L{\´o}ay and M{\"u}ller, Michael A. and Franke, Dirk and Grondal, Christoph and Kurutsch, Anja and Bujnicki, Robert and Takors, Ralf and Raeven, Leon and Wubbolts, Marcel and Bovenberg, Roel and Nieger, Martin and Sch{\"u}rmann, Melanie and Trachtmann, Natalie and Kozak, Stefan and Sprenger, Georg A. and M{\"u}ller, Michael}, title = {Diversity-oriented production of metabolites derived from chorismate and their use in organic synthesis}, series = {Angewandte Chemie International Edition}, volume = {Vol. 50}, journal = {Angewandte Chemie International Edition}, number = {Iss. 34}, publisher = {Wiley}, address = {Weinheim}, issn = {1521-3773 (E-Journal); 0570-0833 (Print); 1433-7851 (Print)}, pages = {7781 -- 7786}, year = {2011}, language = {en} } @article{BongaertsKraemerMuelleretal.2001, author = {Bongaerts, Johannes and Kr{\"a}mer, Marco and M{\"u}ller, Ulrike and Raeven, Leon and Wubbolts, Marcel}, title = {Metabolic engineering for microbial production of aromatic amino acids and derived compounds}, series = {Metabolic engineering}, volume = {Vol. 3}, journal = {Metabolic engineering}, number = {Iss. 4}, issn = {1096-7184 (E-Journal); 1096-7176 (Print)}, pages = {289 -- 300}, year = {2001}, language = {en} } @article{BongaertsZoschkeWeidneretal.1995, author = {Bongaerts, Johannes and Zoschke, Sascha and Weidner, Uwe and Linden, Gottfried}, title = {Transcriptional regulation of the proton translocating NADH}, series = {Molecular microbiology}, volume = {Vol. 16}, journal = {Molecular microbiology}, number = {Iss. 3}, issn = {1365-2958 (E-Journal); 0950-382x (Print)}, pages = {521 -- 534}, year = {1995}, language = {en} } @article{BorgmeierBongaertsMeinhardt2012, author = {Borgmeier, Claudia and Bongaerts, Johannes and Meinhardt, Friedhelm}, title = {Genetic analysis of the Bacillus licheniformis degSU operon and the impact of regulatory mutations on protease production}, series = {Journal of biotechnology}, volume = {159}, journal = {Journal of biotechnology}, number = {1-2}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-4863 (E-Journal); 0168-1656 (Print)}, doi = {10.1016/j.jbiotec.2012.02.011}, pages = {12 -- 20}, year = {2012}, abstract = {Disruption experiments targeted at the Bacillus licheniformis degSU operon and GFP-reporter analysis provided evidence for promoter activity immediately upstream of degU. pMutin mediated concomitant introduction of the degU32 allele - known to cause hypersecretion in Bacillus subtilis - resulted in a marked increase in protease activity. Application of 5-fluorouracil based counterselection through establishment of a phosphoribosyltransferase deficient Δupp strain eventually facilitated the marker-free introduction of degU32 leading to further protease enhancement achieving levels as for hypersecreting wild strains in which degU was overexpressed. Surprisingly, deletion of rapG - known to interfere with DegU DNA-binding in B. subtilis - did not enhance protease production neither in the wild type nor in the degU32 strain. The combination of degU32 and Δupp counterselection in the type strain is not only equally effective as in hypersecreting wild strains with respect to protease production but furthermore facilitates genetic strain improvement aiming at biological containment and effectiveness of biotechnological processes.}, language = {en} } @article{BouwmanGuldenHeijdenetal.2013, author = {Bouwman, Peter and Gulden, Hanneke van der and Heijden, Ingrid van der and Drost, Rinske and Klijn, Christiaan N. and Prasetyanti, Pramudita and Pieterse, Mark and Wientjens, Ellen and Seibler, Jost and Hogervorst, Frank B. L. and Jonkers, Jos}, title = {A High-Throughput Functional Complementation Assay for Classification of BRCA1 Missense Variants}, series = {Cancer Discovery}, journal = {Cancer Discovery}, number = {3}, issn = {2159-8290}, doi = {10.1158/2159-8290.CD-13-0094}, pages = {1142 -- 1152}, year = {2013}, language = {en} } @article{BrabandPaulssenAbram2006, author = {Braband, Henrik and Paulßen, Elisabeth and Abram, Ulrich}, title = {Nitridorhenium(V) Complexes with 1,3-Dialkyl-4,5-dimethylimidazole-2-ylidenes}, series = {Zeitschrift f{\"u}r anorganische und allgemeine Chemie : ZAAC = Journal of inorganic and general chemistry}, volume = {632}, journal = {Zeitschrift f{\"u}r anorganische und allgemeine Chemie : ZAAC = Journal of inorganic and general chemistry}, number = {6}, issn = {1521-3749}, doi = {10.1002/zaac.200600002}, pages = {1051 -- 1056}, year = {2006}, language = {en} } @article{BrabandYegenPaulssenetal.2005, author = {Braband, Henrik and Yegen, Eda and Paulßen, Elisabeth and Abram, Ulrich}, title = {[{ReN(PMe2Ph)3}{ReO3N}]2 - Structural Evidence for the Nitridotrioxorhenate(VII) Anion, [ReO3N]2-}, series = {Zeitschrift f{\"u}r anorganische und allgemeine Chemie : ZAAC = Journal of inorganic and general chemistry}, volume = {631}, journal = {Zeitschrift f{\"u}r anorganische und allgemeine Chemie : ZAAC = Journal of inorganic and general chemistry}, number = {12}, issn = {1521-3749}, doi = {10.1002/zaac.200500240}, pages = {2408 -- 2410}, year = {2005}, language = {en} } @inproceedings{BrandiniBaumann1997, author = {Brandini, Frederico P. and Baumann, Marcus}, title = {The potential role of melted 'brown ice' as sources of chelators and ammonia to the surface waters of the Weddell Sea, Antarctica}, series = {Proceedings of the NIPR Symposium on Polar Biology : 10}, booktitle = {Proceedings of the NIPR Symposium on Polar Biology : 10}, address = {Tokyo}, organization = {National Institute of Polar Research}, issn = {0914-563X}, pages = {1 -- 13}, year = {1997}, language = {en} } @article{BreuerMangSchoeningetal.2017, author = {Breuer, Lars and Mang, Thomas and Sch{\"o}ning, Michael Josef and Thoelen, Ronald and Wagner, Torsten}, title = {Investigation of the spatial resolution of a laser-based stimulation process for light-addressable hydrogels with incorporated graphene oxide by means of IR thermography}, series = {Sensors and Actuators A: Physical}, volume = {268}, journal = {Sensors and Actuators A: Physical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0924-4247}, doi = {10.1016/j.sna.2017.11.031}, pages = {126 -- 132}, year = {2017}, language = {en} } @article{BreuerRaueKirschbaumetal.2015, author = {Breuer, Lars and Raue, Markus and Kirschbaum, M. and Mang, Thomas and Sch{\"o}ning, Michael Josef and Thoelen, R. and Wagner, Torsten}, title = {Light-controllable polymeric material based on temperature-sensitive hydrogels with incorporated graphene oxide}, series = {Physica status solidi (a)}, volume = {212}, journal = {Physica status solidi (a)}, number = {6}, publisher = {Wiley}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201431944}, pages = {1368 -- 1374}, year = {2015}, abstract = {Poly(N-isopropylacrylamide) (PNIPAAm) hydrogel films with incorporated graphene oxide (GO) were developed and tested as light-stimulated actuators. GO dispersions were synthesized via Hummers method and characterized toward their optical properties and photothermal energy conversion. The hydrogels were prepared by means of photopolymerization. In addition, the influence of GO within the hydrogel network on the lower critical solution temperature (LCST) was investigated by differential scanning calorimetry (DSC). The optical absorbance and the response to illumination were determined as a function of GO concentration for thin hydrogel films. A proof of principle for the stimulation with light was performed.}, language = {en} } @inproceedings{BreuerRaueMangetal.2015, author = {Breuer, Lars and Raue, Markus and Mang, Thomas and Sch{\"o}ning, Michael Josef and Thoelen, Ronald and Wagner, Torsten}, title = {Light-stimulated hydrogel actuators with incorporated graphene oxide for microfluidic applications}, series = {12. Dresdner Sensor-Symposium 2015}, booktitle = {12. Dresdner Sensor-Symposium 2015}, doi = {10.5162/12dss2015/P5.8}, pages = {206 -- 209}, year = {2015}, language = {en} } @article{BreuerRaueStrobeletal.2016, author = {Breuer, Lars and Raue, Markus and Strobel, M. and Mang, Thomas and Sch{\"o}ning, Michael Josef and Thoelen, R. and Wagner, Torsten}, title = {Hydrogels with incorporated graphene oxide as light-addressable actuator materials for cell culture environments in lab-on-chip systems}, series = {Physica status solidi (a)}, volume = {213}, journal = {Physica status solidi (a)}, number = {6}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6300}, doi = {10.1002/pssa.201533056}, pages = {1520 -- 1525}, year = {2016}, abstract = {Abstractauthoren Graphene oxide (GO) nanoparticles were incorporated in temperature-sensitive Poly(N-isopropylacrylamide) (PNIPAAm) hydrogels. The nanoparticles increase the light absorption and convert light energy into heat efficiently. Thus, the hydrogels with GO can be stimulated spatially resolved by illumination as it was demonstrated by IR thermography. The temporal progression of the temperature maximum was detected for different concentrations of GO within the polymer network. Furthermore, the compatibility of PNIPAAm hydrogels with GO and cell cultures was investigated. For this purpose, culture medium was incubated with hydrogels containing GO and the viability and morphology of chinese hamster ovary (CHO) cells was examined after several days of culturing in presence of this medium.}, language = {en} } @article{BurgerLindnerRumpfetal.2022, author = {Burger, Ren{\´e} and Lindner, Simon and Rumpf, Jessica and Do, Xuan Tung and Diehl, Bernd W.K. and Rehahn, Matthias and Monakhova, Yulia and Schulze, Margit}, title = {Benchtop versus high field NMR: Comparable performance found for the molecular weight determination of lignin}, series = {Journal of Pharmaceutical and Biomedical Analysis}, volume = {212}, journal = {Journal of Pharmaceutical and Biomedical Analysis}, number = {Article number: 114649}, publisher = {Elsevier}, address = {New York, NY}, isbn = {0731-7085}, doi = {10.1016/j.jpba.2022.114649}, year = {2022}, abstract = {Lignin is a promising renewable biopolymer being investigated worldwide as an environmentally benign substitute of fossil-based aromatic compounds, e.g. for the use as an excipient with antioxidant and antimicrobial properties in drug delivery or even as active compound. For its successful implementation into process streams, a quick, easy, and reliable method is needed for its molecular weight determination. Here we present a method using 1H spectra of benchtop as well as conventional NMR systems in combination with multivariate data analysis, to determine lignin's molecular weight (Mw and Mn) and polydispersity index (PDI). A set of 36 organosolv lignin samples (from Miscanthus x giganteus, Paulownia tomentosa and Silphium perfoliatum) was used for the calibration and cross validation, and 17 samples were used as external validation set. Validation errors between 5.6\% and 12.9\% were achieved for all parameters on all NMR devices (43, 60, 500 and 600 MHz). Surprisingly, no significant difference in the performance of the benchtop and high-field devices was found. This facilitates the application of this method for determining lignin's molecular weight in an industrial environment because of the low maintenance expenditure, small footprint, ruggedness, and low cost of permanent magnet benchtop NMR systems.}, language = {en} } @article{BurgerRumpfDoetal.2021, author = {Burger, Ren{\´e} and Rumpf, Jessica and Do, Xuan Tung and Monakhova, Yulia and Diehl, Bernd W. K. and Rehahn, Matthias and Schulze, Margit}, title = {Is NMR combined with multivariate regression applicable for the molecular weight determination of randomly cross-linked polymers such as lignin?}, series = {ACS Omega}, volume = {6}, journal = {ACS Omega}, number = {44}, publisher = {ACS Publications}, address = {Washington, DC}, issn = {2470-1343}, doi = {10.1021/acsomega.1c03574}, pages = {29516 -- 29524}, year = {2021}, abstract = {The molecular weight properties of lignins are one of the key elements that need to be analyzed for a successful industrial application of these promising biopolymers. In this study, the use of 1H NMR as well as diffusion-ordered spectroscopy (DOSY NMR), combined with multivariate regression methods, was investigated for the determination of the molecular weight (Mw and Mn) and the polydispersity of organosolv lignins (n = 53, Miscanthus x giganteus, Paulownia tomentosa, and Silphium perfoliatum). The suitability of the models was demonstrated by cross validation (CV) as well as by an independent validation set of samples from different biomass origins (beech wood and wheat straw). CV errors of ca. 7-9 and 14-16\% were achieved for all parameters with the models from the 1H NMR spectra and the DOSY NMR data, respectively. The prediction errors for the validation samples were in a similar range for the partial least squares model from the 1H NMR data and for a multiple linear regression using the DOSY NMR data. The results indicate the usefulness of NMR measurements combined with multivariate regression methods as a potential alternative to more time-consuming methods such as gel permeation chromatography.}, language = {en} } @article{BurmistrovaSobolevaMonakhova2021, author = {Burmistrova, Natalia A. and Soboleva, Polina M. and Monakhova, Yulia}, title = {Is infrared spectroscopy combined with multivariate analysis a promising tool for heparin authentication?}, series = {Journal of Pharmaceutical and Biomedical Analysis}, volume = {194}, journal = {Journal of Pharmaceutical and Biomedical Analysis}, number = {Article number: 113811}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {0731-7085}, doi = {10.1016/j.jpba.2020.113811}, year = {2021}, abstract = {The investigation of the possibility to determine various characteristics of powder heparin (n = 115) was carried out with infrared spectroscopy. The evaluation of heparin samples included several parameters such as purity grade, distributing company, animal source as well as heparin species (i.e. Na-heparin, Ca-heparin, and heparinoids). Multivariate analysis using principal component analysis (PCA), soft independent modelling of class analogy (SIMCA), and partial least squares - discriminant analysis (PLS-DA) were applied for the modelling of spectral data. Different pre-processing methods were applied to IR spectral data; multiplicative scatter correction (MSC) was chosen as the most relevant. Obtained results were confirmed by nuclear magnetic resonance (NMR) spectroscopy. Good predictive ability of this approach demonstrates the potential of IR spectroscopy and chemometrics for screening of heparin quality. This approach, however, is designed as a screening tool and is not considered as a replacement for either of the methods required by USP and FDA.}, language = {en} } @article{BaeckerBegingBisellietal.2009, author = {B{\"a}cker, Matthias and Beging, Stefan and Biselli, Manfred and Poghossian, Arshak and Wang, J. and Zang, Werner and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Concept for a solid-state multi-parameter sensor system for cell-culture monitoring}, series = {Electrochimica Acta. 54 (2009), H. 25 Sp. Iss. SI}, journal = {Electrochimica Acta. 54 (2009), H. 25 Sp. Iss. SI}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {0013-4686}, pages = {6107 -- 6112}, year = {2009}, language = {en} } @article{BaeckerDellePoghossianetal.2011, author = {B{\"a}cker, Matthias and Delle, L. and Poghossian, Arshak and Biselli, Manfred and Zang, Werner and Wagner, P. and Sch{\"o}ning, Michael Josef}, title = {Electrochemical sensor array for bioprocess monitoring}, series = {Electrochimica Acta (2011)}, volume = {56}, journal = {Electrochimica Acta (2011)}, number = {26}, publisher = {Elsevier}, address = {Amsterdam}, pages = {9673 -- 9678}, year = {2011}, language = {en} } @article{BaeckerRakowskiPoghossianetal.2013, author = {B{\"a}cker, Matthias and Rakowski, D. and Poghossian, Arshak and Biselli, Manfred and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Chip-based amperometric enzyme sensor system for monitoring of bioprocesses by flow-injection analysis}, series = {Journal of Biotechnology}, volume = {163}, journal = {Journal of Biotechnology}, number = {4}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0168-1656}, doi = {10.1016/j.jbiotec.2012.03.014}, pages = {371 -- 376}, year = {2013}, abstract = {A microfluidic chip integrating amperometric enzyme sensors for the detection of glucose, glutamate and glutamine in cell-culture fermentation processes has been developed. The enzymes glucose oxidase, glutamate oxidase and glutaminase were immobilized by means of cross-linking with glutaraldehyde on platinum thin-film electrodes integrated within a microfluidic channel. The biosensor chip was coupled to a flow-injection analysis system for electrochemical characterization of the sensors. The sensors have been characterized in terms of sensitivity, linear working range and detection limit. The sensitivity evaluated from the respective peak areas was 1.47, 3.68 and 0.28 μAs/mM for the glucose, glutamate and glutamine sensor, respectively. The calibration curves were linear up to a concentration of 20 mM glucose and glutamine and up to 10 mM for glutamate. The lower detection limit amounted to be 0.05 mM for the glucose and glutamate sensor, respectively, and 0.1 mM for the glutamine sensor. Experiments in cell-culture medium have demonstrated a good correlation between the glutamate, glutamine and glucose concentrations measured with the chip-based biosensors in a differential-mode and the commercially available instrumentation. The obtained results demonstrate the feasibility of the realized microfluidic biosensor chip for monitoring of bioprocesses.}, language = {en} } @article{BaeckerRaueSchusseretal.2012, author = {B{\"a}cker, Matthias and Raue, Markus and Schusser, Sebastian and Jeitner, C. and Breuer, L. and Wagner, P. and Poghossian, Arshak and F{\"o}rster, Arnold and Mang, Thomas and Sch{\"o}ning, Michael Josef}, title = {Microfluidic chip with integrated microvalves based on temperature- and pH-responsive hydrogel thin films}, series = {Physica Status Solidi (a)}, volume = {209}, journal = {Physica Status Solidi (a)}, number = {5}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201100763}, pages = {839 -- 845}, year = {2012}, abstract = {Two types of microvalves based on temperature-responsive poly(N-isopropylacrylamide) (PNIPAAm) and pH-responsive poly(sodium acrylate) (PSA) hydrogel films have been developed and tested. The PNIPAAm and PSA hydrogel films were prepared by means of in situ photopolymerization directly inside the fluidic channel of a microfluidic chip fabricated by combining Si and SU-8 technologies. The swelling/shrinking properties and height changes of the PNIPAAm and PSA films inside the fluidic channel were studied at temperatures of deionized water from 14 to 36 °C and different pH values (pH 3-12) of Titrisol buffer, respectively. Additionally, in separate experiments, the lower critical solution temperature (LCST) of the PNIPAAm hydrogel was investigated by means of a differential scanning calorimetry (DSC) and a surface plasmon resonance (SPR) method. Mass-flow measurements have shown the feasibility of the prepared hydrogel films to work as an on-chip integrated temperature- or pH-responsive microvalve capable to switch the flow channel on/off.}, language = {en} } @article{CanzoneriKruegerZangetal.2006, author = {Canzoneri, M. and Kr{\"u}ger, R. and Zang, Werner and Biselli, Manfred}, title = {Atmungsaktivit{\"a}t von S{\"a}ugerzellen: Kontinuierliche Onlineermittlung im Sch{\"u}ttelkolben}, series = {BIOforum. 3 (2006)}, journal = {BIOforum. 3 (2006)}, isbn = {0940-0079}, pages = {45 -- 47}, year = {2006}, language = {de} } @inproceedings{CapitainHeringTippkoetteretal.2016, author = {Capitain, C. and Hering, T. and Tippk{\"o}tter, Nils and Ulber, R.}, title = {Enzymatic polymerization of lignin model compounds and solubilized lignin in an aqueous ethanol extract}, series = {New frontiers of biotech-processes (Himmelfahrtstagung) : 02-04 May 2016, Rhein-Mosel-Halle, Koblenz/Germany}, booktitle = {New frontiers of biotech-processes (Himmelfahrtstagung) : 02-04 May 2016, Rhein-Mosel-Halle, Koblenz/Germany}, publisher = {DECHEMA}, address = {Frankfurt am Main}, pages = {151 -- 152}, year = {2016}, language = {en} } @article{CapitainRossJonesMoehringetal.2020, author = {Capitain, Charlotte and Ross-Jones, Jesse and M{\"o}hring, Sophie and Tippk{\"o}tter, Nils}, title = {Differential scanning calorimetry for quantification of polymer biodegradability in compost}, series = {International Biodeterioration \& Biodegradation}, volume = {149}, journal = {International Biodeterioration \& Biodegradation}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0964-8305}, doi = {10.1016/j.ibiod.2020.104914}, pages = {In Press, Article number 104914}, year = {2020}, abstract = {The objective of this study is the establishment of a differential scanning calorimetry (DSC) based method for online analysis of the biodegradation of polymers in complex environments. Structural changes during biodegradation, such as an increase in brittleness or crystallinity, can be detected by carefully observing characteristic changes in DSC profiles. Until now, DSC profiles have not been used to draw quantitative conclusions about biodegradation. A new method is presented for quantifying the biodegradation using DSC data, whereby the results were validated using two reference methods. The proposed method is applied to evaluate the biodegradation of three polymeric biomaterials: polyhydroxybutyrate (PHB), cellulose acetate (CA) and Organosolv lignin. The method is suitable for the precise quantification of the biodegradability of PHB. For CA and lignin, conclusions regarding their biodegradation can be drawn with lower resolutions. The proposed method is also able to quantify the biodegradation of blends or composite materials, which differentiates it from commonly used degradation detection methods.}, language = {en} } @article{CehreliAkpinarTemizArtmannetal.2015, author = {Cehreli, Ruksan and Akpinar, Hale and Temiz Artmann, Ayseg{\"u}l and Sagol, Ozgul}, title = {Effects of Glutamine and Omega-3 Fatty Acids on Erythrocyte Deformability and Oxidative Damage in Rat Model of Enterocolitis}, series = {Gastroenterology Research}, volume = {8}, journal = {Gastroenterology Research}, number = {5}, issn = {1918-2813}, doi = {10.14740/gr683w}, pages = {265 -- 273}, year = {2015}, language = {en} } @article{CesariRennekampffVinterstenetal.2004, author = {Cesari, Francesca and Rennekampff, Verena and Vintersten, Kristina and Vuong, Lam Giang and Seibler, Jost and Bode, J{\"u}rgen and Wiebel, Franziska F. and Nordheim, Alfred}, title = {Elk-1 knock-out mice engineered by Flp recombinase-mediated cassette exchange}, series = {Genesis : The Journal of Genetics and Development}, volume = {38}, journal = {Genesis : The Journal of Genetics and Development}, number = {2}, issn = {1526-968X}, doi = {10.1002/gene.20003}, pages = {87 -- 92}, year = {2004}, language = {en} } @article{ChristophBahrenbergVryetal.2008, author = {Christoph, Thomas and Bahrenberg, Gregor and Vry, Jean de and Englberger, Werner and Erdmann, Volker A. and Frech, Moritz and K{\"o}gel, Babette and R{\"o}hl, Thomas and Schiene, Klaus and Schr{\"o}der, Wolfgang and Seibler, Jost and Kurreck, Jens}, title = {Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice}, series = {Molecular and Cellular Neuroscience}, volume = {37}, journal = {Molecular and Cellular Neuroscience}, number = {3}, issn = {1044-7431}, doi = {10.1016/j.mcn.2007.12.006}, pages = {579 -- 589}, year = {2008}, language = {en} } @article{ClaessenGrefenMangetal.2010, author = {Claessen, O. and Grefen, Dana and Mang, Thomas and Dikland, H. G. and Dikland, H. G. and Duin, M. van}, title = {Helle Fensterprofilmaterialien : Alterungsverhalten auf Basis von peroxidisch vernetztem EPDM}, series = {Kautschuk, Gummi, Kunststoffe : KGK}, volume = {63}, journal = {Kautschuk, Gummi, Kunststoffe : KGK}, number = {9}, isbn = {0948-3276}, pages = {350 -- 360}, year = {2010}, language = {de} } @article{DallasSalphatiGomezZepedaetal.2016, author = {Dallas, Shannon and Salphati, Laurent and Gomez-Zepeda, David and Wanek, Thomas and Chen, Liangfu and Chu, Xiaoyan and Kunta, Jeevan and Mezler, Mario and Menet, Marie-Claude and Chasseigneaux, Stephanie and Decl{\`e}ves, Xavier and Langer, Oliver and Pierre, Esaie and DiLoreto, Karen and Hoft, Carolin and Laplanche, Loic and Pang, Jodie and Pereira, Tony and Andonian, Clara and Simic, Damir and Rode, Anja and Yabut, Jocelyn and Zhang, Xiaolin and Scheer, Nico}, title = {Generation and Characterization of a Breast Cancer Resistance Protein Humanized Mouse Model}, series = {Molecular Pharmacology}, volume = {89}, journal = {Molecular Pharmacology}, number = {5}, publisher = {ASPET}, address = {Bethesda, Md.}, issn = {1521-0111}, doi = {10.1124/mol.115.102079}, pages = {492 -- 504}, year = {2016}, abstract = {Breast cancer resistance protein (BCRP) is expressed in various tissues, such as the gut, liver, kidney and blood brain barrier (BBB), where it mediates the unidirectional transport of substrates to the apical/luminal side of polarized cells. Thereby BCRP acts as an efflux pump, mediating the elimination or restricting the entry of endogenous compounds or xenobiotics into tissues and it plays important roles in drug disposition, efficacy and safety. Bcrp knockout mice (Bcrp-/-) have been used widely to study the role of this transporter in limiting intestinal absorption and brain penetration of substrate compounds. Here we describe the first generation and characterization of a mouse line humanized for BCRP (hBCRP), in which the mouse coding sequence from the start to stop codon was replaced with the corresponding human genomic region, such that the human transporter is expressed under control of the murine Bcrp promoter. We demonstrate robust human and loss of mouse BCRP/Bcrp mRNA and protein expression in the hBCRP mice and the absence of major compensatory changes in the expression of other genes involved in drug metabolism and disposition. Pharmacokinetic and brain distribution studies with several BCRP probe substrates confirmed the functional activity of the human transporter in these mice. Furthermore, we provide practical examples for the use of hBCRP mice to study drug-drug interactions (DDIs). The hBCRP mouse is a promising model to study the in vivo role of human BCRP in limiting absorption and BBB penetration of substrate compounds and to investigate clinically relevant DDIs involving BCRP.}, language = {en} } @article{DanhoNaithaniSasakietal.1980, author = {Danho, Waleed and Naithani, Vinod K. and Sasaki, Andr{\´e} N. and F{\"o}hles, Joseph and Berndt, Heinz and [u.a.],}, title = {Human proinsulin, VII : synthesis of two protected peptides corresponding to the sequences 1—45 and 46—86 of the prohormone}, series = {Hoppe-Seyler's Zeitschrift f{\"u}r physiologische Chemie}, volume = {361}, journal = {Hoppe-Seyler's Zeitschrift f{\"u}r physiologische Chemie}, number = {1}, issn = {1437-4315}, doi = {10.1515/bchm2.1980.361.1.857}, pages = {857 -- 863}, year = {1980}, language = {en} } @misc{DauerHojdisMuelleretal.2019, author = {Dauer, David-Raphael and Hojdis, Nils and M{\"u}ller, Norbert and Recker, Carla and Schax, Fabian and Sch{\"o}ffel, Julia and Tarantola, Gesa and Weber, Christine}, title = {Schwefelvernetzbare Kautschukmischung, Vulkanisat der Kautschukmischung und Fahrzeugreifen}, year = {2019}, abstract = {Die Erfindung betrifft eine schwefelvernetzbare Kautschukmischung, deren Vulkanisat und einen Fahrzeugreifen. Die schwefelvernetzbare Kautschukmischung enth{\"a}lt wenigstens die folgenden Bestandteile: - wenigstens einen Dienkautschuk; und - 10 bis 300 phr wenigstens einer Kiesels{\"a}ure; und - 1 bis 30 phf wenigstens eines Silans A mit der allgemeinen Summenformel A-I) A-I)(R1)oSi-R2-(S-R3)q-S-X; und - 0,5 bis 30 phf wenigstens eines Silans B mit der allgemeinen Summenformel B-I) B-I) (R1)oSi-R2-(S-R3)u-S-R2-Si(R1)o wobei q =1, 2 oder 3 ist; und u = 1, 2 oder 3 ist; und X ein Wasserstoffatom oder eine -C(=O)-R8 Gruppe ist wobei R8 ausgew{\"a}hlt ist aus Wasserstoff, C1-C20 Alkylgruppen, vorzugsweise C1-C17, C6-C20- Arylgruppen, vorzugsweise Phenyl, C2-C20-Alkenylgruppen und C7-C20-Aralkylgruppen.}, language = {de} } @misc{DauerHojdisMuelleretal.2019, author = {Dauer, David-Raphael and Hojdis, Nils and M{\"u}ller, Norbert and Recker, Carla and Schax, Fabian and Sch{\"o}ffel, Julia and Tarantola, Gesa and Weber, Christine}, title = {Schwefelvernetzbare Kautschukmischung, Vulkanisat der Kautschukmischung und Fahrzeugreifen}, year = {2019}, abstract = {Die Erfindung betrifft eine schwefelvernetzbare Kautschukmischung, deren Vulkanisat und einen Fahrzeugreifen.Die schwefelvernetzbare Kautschukmischung enth{\"a}lt wenigstens die folgenden Bestandteile:- wenigstens einen Dienkautschuk; und- 10 bis 300 phr wenigstens einer Kiesels{\"a}ure ; und- 1 bis 30 phf wenigstens eines Silans A mit der allgemeinen Summenformel A-I)und- 0,5 bis 30 phf wenigstens eines Silans B mit der allgemeinen Summenformel B-I)wobei u gleich 0, 1, 2 oder 3 und v gleich 0 oder 1 ist.}, language = {de} } @article{DegeringEggertPulsetal.2010, author = {Degering, Christian and Eggert, Thorsten and Puls, Michael and Bongaerts, Johannes and Evers, Stefan and Maurer, Karl-Heinz and Jaeger, Karl-Erich}, title = {Optimization of protease secretion in Bacillus subtilis and Bacillus licheniformis by screening of homologous and herologous signal peptides}, series = {Applied and environmental microbiology}, volume = {76}, journal = {Applied and environmental microbiology}, number = {19}, publisher = {American Society for Microbiology}, address = {Washington, DC}, issn = {1098-5336 (E-Journal); 0003-6919 (Print); 0099-2240 (Print)}, doi = {10.1128/AEM.01146-10}, pages = {6370 -- 6378}, year = {2010}, abstract = {Bacillus subtilis and Bacillus licheniformis are widely used for the large-scale industrial production of proteins. These strains can efficiently secrete proteins into the culture medium using the general secretion (Sec) pathway. A characteristic feature of all secreted proteins is their N-terminal signal peptides, which are recognized by the secretion machinery. Here, we have studied the production of an industrially important secreted protease, namely, subtilisin BPN′ from Bacillus amyloliquefaciens. One hundred seventy-three signal peptides originating from B. subtilis and 220 signal peptides from the B. licheniformis type strain were fused to this secretion target and expressed in B. subtilis, and the resulting library was analyzed by high-throughput screening for extracellular proteolytic activity. We have identified a number of signal peptides originating from both organisms which produced significantly increased yield of the secreted protease. Interestingly, we observed that levels of extracellular protease were improved not only in B. subtilis, which was used as the screening host, but also in two different B. licheniformis strains. To date, it is impossible to predict which signal peptide will result in better secretion and thus an improved yield of a given extracellular target protein. Our data show that screening a library consisting of homologous and heterologous signal peptides fused to a target protein can identify more-effective signal peptides, resulting in improved protein export not only in the original screening host but also in different production strains.}, language = {en} } @article{Delaittre2019, author = {Delaittre, Guillaume}, title = {Telechelic Poly(2-Oxazoline)s}, series = {European Polymer Journal}, journal = {European Polymer Journal}, number = {In Press, Journal Pre-proof, 109281}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0014-3057}, doi = {10.1016/j.eurpolymj.2019.109281}, year = {2019}, language = {en} } @article{DellmannGloriusLitvinovetal.2023, author = {Dellmann, Sophia Florence and Glorius, J. and Litvinov, Yu A. and Reifarth, R. and Al-Khasawneh, Kafa and Aliotta, M. and Bott, L. and Br{\"u}ckner, Benjamin and Bruno, C. G. and Chen, Ruijiu and Davinson, T. and Dickel, T. and Dillmann, Iris and Dmytriev, D. and Erbacher, P. and Freire-Fern{\´a}ndez, D. and Forstner, Oliver and Geissel, H. and G{\"o}bel, K. and Griffin, Christopher J. and Grisenti, R. and Gumberidze, Alexandre and Haettner, Emma and Hagmann, Siegbert and Heil, M. and Heß, R. and Hillenbrand, P.-M. and Joseph, R. and Jurado, B. and Kozhuharov, Christophor and Kulikov, I. and L{\"o}her, Bastian and Langer, Christoph and Leckenby, Guy and Lederer-Woods, C. and Lestinsky, M. and Litvinov, S. A. and Lorenz, B. A. and Lorenz, E. and Marsh, J. and Menz, Esther Babette and Morgenroth, T. and Petridis, N. and Pibernat, Jerome and Popp, U. and Psaltis, Athanasios and Sanjari, Shahab and Scheidenberger, C. and Sguazzin, M. and Sidhu, Ragandeep Singh and Spillmann, Uwe and Steck, M. and St{\"o}hlker, T. and Surzhykov, A. and Swartz, J. A. and T{\"o}rnqvist, H. and Varga, L. and Vescovi, Diego and Weick, H. and Weigand, M. and Woods, P. and Xing, Y. and Yamaguchi, Taiyo}, title = {Proton capture on stored radioactive ¹¹⁸Te ions}, series = {EPJ Web of Conferences}, volume = {279}, journal = {EPJ Web of Conferences}, number = {Article Number: 11018}, publisher = {EDP Sciences}, issn = {2100-014X}, doi = {10.1051/epjconf/202327911018}, pages = {1 -- 5}, year = {2023}, abstract = {Experimental determination of the cross sections of proton capture on radioactive nuclei is extremely difficult. Therefore, it is of substantial interest for the understanding of the production of the p-nuclei. For the first time, a direct measurement of proton-capture cross sections on stored, radioactive ions became possible in an energy range of interest for nuclear astrophysics. The experiment was performed at the Experimental Storage Ring (ESR) at GSI by making use of a sensitive method to measure (p,γ) and (p,n) reactions in inverse kinematics. These reaction channels are of high relevance for the nucleosyn-thesis processes in supernovae, which are among the most violent explosions in the universe and are not yet well understood. The cross section of the ¹¹⁸Te(p,γ) reaction has been measured at energies of 6 MeV/u and 7 MeV/u. The heavy ions interacted with a hydrogen gas jet target. The radiative recombination process of the fully stripped ¹¹⁸Te ions and electrons from the hydrogen target was used as a luminosity monitor. An overview of the experimental method and preliminary results from the ongoing analysis will be presented.}, language = {en} } @article{DemmerChowdhurySelmeretal.2017, author = {Demmer, Julius K. and Chowdhury, Nilanjan Pal and Selmer, Thorsten and Ermler, Ulrich and Buckel, Wolfgang}, title = {The semiquinone swing in the bifurcating electron transferring flavoprotein/butyryl-CoA dehydrogenase complex from Clostridium difficile}, series = {Nature Communications}, volume = {8}, journal = {Nature Communications}, number = {1}, issn = {2041-1723}, doi = {10.1038/s41467-017-01746-3}, pages = {1 -- 10}, year = {2017}, language = {en} } @article{DeppeBongaertsO'Connelletal.2011, author = {Deppe, Veronika Maria and Bongaerts, Johannes and O'Connell, Timothy and Maurer, Karl-Heinz and Meinhardt, Friedhelm}, title = {Enzymatic deglycation of Amadori products in bacteria}, series = {Applied microbiology and biotechnology}, volume = {Vol. 90}, journal = {Applied microbiology and biotechnology}, number = {Iss. 2}, publisher = {Springer}, address = {Berlin}, issn = {1432-0614 (E-Journal); 0171-1741 (Print); 0175-7598 (Print); 0340-2118 (Print)}, pages = {399 -- 406}, year = {2011}, language = {en} } @article{DeppeKlatteBongaertsetal.2011, author = {Deppe, Veronika Maria and Klatte, Stephanie and Bongaerts, Johannes and Maurer, Karl-Heinz and O'Connell, Timothy and Meinhardt, Friedhelm}, title = {Genetic control of Amadori product degradation in Bacillus subtilis via regulation of frlBONMD expression by FrlR}, series = {Applied and environmental microbiology}, volume = {Vol. 77}, journal = {Applied and environmental microbiology}, number = {No. 9}, publisher = {American Society of Mechanical Engineers (ASME)}, address = {New York}, issn = {1098-5336 (E-Journal); 0003-6919 (Print); 0099-2240 (Print)}, pages = {2839 -- 2846}, year = {2011}, language = {en} } @inproceedings{DeterdingTippkoetterUlber2006, author = {Deterding, A. and Tippk{\"o}tter, Nils and Ulber, R.}, title = {Online-Essigs{\"a}ureanalytik in Fermentationsbr{\"u}hen mittels Fließdiffusionstechnik (FDT)}, series = {Technische Systeme f{\"u}r Biotechnologie und Umwelt : 13. Heiligenst{\"a}dter Kolloquium, Heilbad Heiligenstadt, 25.09. - 27.09.2006}, booktitle = {Technische Systeme f{\"u}r Biotechnologie und Umwelt : 13. Heiligenst{\"a}dter Kolloquium, Heilbad Heiligenstadt, 25.09. - 27.09.2006}, editor = {Beckmann, Dieter}, address = {Heiligenstadt}, organization = {Institut f{\"u}r Bioprozeß- und Analysenmeßtechnik}, isbn = {978-3-00-018621-9}, pages = {273 -- 280}, year = {2006}, language = {de} } @article{DruckenmuellerGuentherElbers2018, author = {Druckenm{\"u}ller, Katharina and G{\"u}nther, Klaus and Elbers, Gereon}, title = {Near-infrared spectroscopy (NIRS) as a tool to monitor exhaust air from poultry operations}, series = {Science of the Total Environment}, volume = {630}, journal = {Science of the Total Environment}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0048-9697}, doi = {10.1016/j.scitotenv.2018.02.072}, pages = {536 -- 543}, year = {2018}, abstract = {Intensive poultry operation systems emit a considerable volume of inorganic and organic matter in the surrounding environment. Monitoring cleaning properties of exhaust air cleaning systems and to detect small but significant changes in emission characteristics during a fattening cycle is important for both emission and fattening process control. In the present study, we evaluated the potential of near-infrared spectroscopy (NIRS) combined with chemometric techniques as a monitoring tool of exhaust air from poultry operation systems. To generate a high-quality data set for evaluation, the exhaust air of two poultry houses was sampled by applying state-of-the-art filter sampling protocols. The two stables were identical except for one crucial difference, the presence or absence of an exhaust air cleaning system. In total, twenty-one exhaust air samples were collected at the two sites to monitor spectral differences caused by the cleaning device, and to follow changes in exhaust air characteristics during a fattening period. The total dust load was analyzed by gravimetric determination and included as a response variable in multivariate data analysis. The filter samples were directly measured with NIR spectroscopy. Principal component analysis (PCA), linear discriminant analysis (LDA), and factor analysis (FA) were effective in classifying the NIR exhaust air spectra according to fattening day and origin. The results indicate that the dust load and the composition of exhaust air (inorganic or organic matter) substantially influence the NIR spectral patterns. In conclusion, NIR spectroscopy as a tool is a promising and very rapid way to detect differences between exhaust air samples based on still not clearly defined circumstances triggered during a fattening period and the availability of an exhaust air cleaning system.}, language = {en} } @incollection{DuongSeifarthTemizArtmannetal.2018, author = {Duong, Minh Tuan and Seifarth, Volker and Temiz Artmann, Ayseg{\"u}l and Artmann, Gerhard and Staat, Manfred}, title = {Growth Modelling Promoting Mechanical Stimulation of Smooth Muscle Cells of Porcine Tubular Organs in a Fibrin-PVDF Scaffold}, series = {Biological, Physical and Technical Basics of Cell Engineering}, booktitle = {Biological, Physical and Technical Basics of Cell Engineering}, editor = {Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Zhubanova, Azhar A. and Digel, Ilya}, publisher = {Springer}, address = {Singapore}, isbn = {978-981-10-7904-7}, doi = {10.1007/978-981-10-7904-7_9}, pages = {209 -- 232}, year = {2018}, abstract = {Reconstructive surgery and tissue replacements like ureters or bladders reconstruction have been recently studied, taking into account growth and remodelling of cells since living cells are capable of growing, adapting, remodelling or degrading and restoring in order to deform and respond to stimuli. Hence, shapes of ureters or bladders and their microstructure change during growth and these changes strongly depend on external stimuli such as training. We present the mechanical stimulation of smooth muscle cells in a tubular fibrin-PVDFA scaffold and the modelling of the growth of tissue by stimuli. To this end, mechanotransduction was performed with a kyphoplasty balloon catheter that was guided through the lumen of the tubular structure. The bursting pressure was examined to compare the stability of the incubated tissue constructs. The results showed the significant changes on tissues with training by increasing the burst pressure as a characteristic mechanical property and the smooth muscle cells were more oriented with uniformly higher density. Besides, the computational growth models also exhibited the accurate tendencies of growth of the cells under different external stimuli. Such models may lead to design standards for the better layered tissue structure in reconstructing of tubular organs characterized as composite materials such as intestines, ureters and arteries.}, language = {en} } @article{DuttaHartkopfFroederWitteetal.2013, author = {Dutta, Suryendu and Hartkopf-Fr{\"o}der, Christoph and Witte, Karin and Brocke, Rainer and Mann, Ulrich}, title = {Molecular characterization of fossil palynomorphs by transmission micro-FTIR spectroscopy: implications for hydrocarbon source evaluation}, series = {International journal of coal geology}, volume = {Vol. 115}, journal = {International journal of coal geology}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1872-7840 (E-Journal); 0166-5162 (Print)}, pages = {13 -- 23}, year = {2013}, language = {en} } @incollection{DuweTippkoetterUlber2018, author = {Duwe, A. and Tippk{\"o}tter, Nils and Ulber, R.}, title = {Lignocellulose-Biorefinery: Ethanol-Focused}, series = {Biorefineries}, booktitle = {Biorefineries}, publisher = {Springer}, address = {Cham}, doi = {10.1007/10_2016_72}, pages = {177 -- 215}, year = {2018}, abstract = {The development prospects of the world markets for petroleum and other liquid fuels are diverse and partly contradictory. However, comprehensive changes for the energy supply of the future are essential. Notwithstanding the fact that there are still very large deposits of energy resources from a geological point of view, the finite nature of conventional oil reserves is indisputable. To reduce our dependence on oil, the EU, the USA, and other major economic zones rely on energy diversification. For this purpose, alternative materials and technologies are being sought, and is most obvious in the transport sector. The objective is to progressively replace fossil fuels with renewable and more sustainable fuels. In this respect, biofuels have a pre-eminent position in terms of their capability of blending with fossil fuels and being usable in existing cars without substantial modification. Ethanol can be considered as the primary renewable liquid fuel. In this chapter enzymes, micro-organisms, and processes for ethanol production based on renewable resources are described.}, language = {en} } @article{DuenkelmannKolterJungNitscheetal.2002, author = {D{\"u}nkelmann, Pascal and Kolter-Jung, Doris and Nitsche, Adam and Demir, Ayhan S. and Siegert, Petra and Lingen, Bettina and Baumann, Martin and Pohl, Martina and M{\"u}ller, Michael}, title = {Development of a donor-acceptor concept for enzymatic cross-coupling reactions of adehydes : the first asymmetric cross-benzoin condensation}, series = {Journal of the American Chemical Society}, volume = {Vol. 124}, journal = {Journal of the American Chemical Society}, issn = {1520-5126 (E-Journal); 0002-7863 (Print)}, pages = {12084 -- 12085}, year = {2002}, language = {en} } @article{DuennwaldDemirSiegertetal.2001, author = {D{\"u}nnwald, Thomas and Demir, Ayhan S. and Siegert, Petra and Pohl, Martina and M{\"u}ller, Michael}, title = {ChemInform Abstract: Enantioselective synthesis of (S)-2-Hydroxypropanone derivatives by Benzoylformate Decarboxylase Catalyzed C—C Bond Formation}, series = {Cheminform}, volume = {Vol. 32}, journal = {Cheminform}, number = {Iss. 4}, issn = {1522-2667 (E-Journal); 0931-7597 (Print)}, pages = {Publ. online}, year = {2001}, language = {en} } @article{DuennwaldDemirSiegertetal.2000, author = {D{\"u}nnwald, Thomas and Demir, Ayhan S. and Siegert, Petra and Pohl, Martina and M{\"u}ller, Michael}, title = {Enantioselective Synthesis of (S)-2-Hydroxypropanone Derivatives by Benzoylformate Decarboxylase Catalyzed C-C Bond Formation}, series = {European journal of organic chemistry}, volume = {Vol. 2000}, journal = {European journal of organic chemistry}, number = {Iss. 11}, issn = {0365-5490 (E-Journal); 1099-0690 (E-Journal); 0075-4617 (Print); 0170-2041 (Print); 0947-3440 (Print); 1434-193X (Print); 1434-243X (Print)}, pages = {2161 -- 2170}, year = {2000}, language = {en} } @article{EckertAbbasiMangetal.2020, author = {Eckert, Alexander and Abbasi, Mozhdeh and Mang, Thomas and Saalw{\"a}chter, Kay and Walther, Andreas}, title = {Structure, Mechanical Properties, and Dynamics of Polyethylenoxide/Nanoclay Nacre-Mimetic Nanocomposites}, series = {Macromolecules}, volume = {53}, journal = {Macromolecules}, number = {5}, publisher = {ACS Publications}, address = {Washington, DC}, issn = {1520-5835}, doi = {10.1021/acs.macromol.9b01931}, pages = {1716 -- 1725}, year = {2020}, abstract = {Nacre-mimetic nanocomposites based on high fractions of synthetic high-aspect-ratio nanoclays in combination with polymers are continuously pushing boundaries for advanced material properties, such as high barrier against oxygen, extraordinary mechanical behavior, fire shielding, and glass-like transparency. Additionally, they provide interesting model systems to study polymers under nanoconfinement due to the well-defined layered nanocomposite arrangement. Although the general behavior in terms of forming such layered nanocomposite materials using evaporative self-assembly and controlling the nanoclay gallery spacing by the nanoclay/polymer ratio is understood, some combinations of polymer matrices and nanoclay reinforcement do not comply with the established models. Here, we demonstrate a thorough characterization and analysis of such an unusual polymer/nanoclay pair that falls outside of the general behavior. Poly(ethylene oxide) (PEO) and sodium fluorohectorite form nacre-mimetic, lamellar nanocomposites that are completely transparent and show high mechanical stiffness and high gas barrier, but there is only limited expansion of the nanoclay gallery spacing when adding increasing amounts of polymer. This behavior is maintained for molecular weights of PEO varied over four orders of magnitude and can be traced back to depletion forces. By careful investigation via X-ray diffraction and proton low-resolution solid-state NMR, we are able to quantify the amount of mobile and immobilized polymer species in between the nanoclay galleries and around proposed tactoid stacks embedded in a PEO matrix. We further elucidate the unusual confined polymer dynamics, indicating a relevant role of specific surface interactions.}, language = {en} } @article{EckertRudolphGuoetal.2018, author = {Eckert, Alexander and Rudolph, Tobias and Guo, Jiaqi and Mang, Thomas and Walther, Andreas}, title = {Exceptionally Ductile and Tough Biomimetic Artificial Nacre with Gas Barrier Function}, series = {Advanced Materials}, volume = {30}, journal = {Advanced Materials}, number = {32}, publisher = {Wiley-VCH}, doi = {10.1002/adma.201802477}, pages = {Article number 1802477}, year = {2018}, abstract = {Synthetic mimics of natural high-performance structural materials have shown great and partly unforeseen opportunities for the design of multifunctional materials. For nacre-mimetic nanocomposites, it has remained extraordinarily challenging to make ductile materials with high stretchability at high fractions of reinforcements, which is however of crucial importance for flexible barrier materials. Here, highly ductile and tough nacre-mimetic nanocomposites are presented, by implementing weak, but many hydrogen bonds in a ternary nacre-mimetic system consisting of two polymers (poly(vinyl amine) and poly(vinyl alcohol)) and natural nanoclay (montmorillonite) to provide efficient energy dissipation and slippage at high nanoclay content (50 wt\%). Tailored interactions enable exceptional combinations of ductility (close to 50\% strain) and toughness (up to 27.5 MJ m⁻³). Extensive stress whitening, a clear sign of high internal dynamics at high internal cohesion, can be observed during mechanical deformation, and the materials can be folded like paper into origami planes without fracture. Overall, the new levels of ductility and toughness are unprecedented in highly reinforced bioinspired nanocomposites and are of critical importance to future applications, e.g., as barrier materials needed for encapsulation and as a printing substrate for flexible organic electronics.}, language = {en} } @misc{EhmkeFingerHojdisetal.2020, author = {Ehmke, Tobias and Finger, Sebastian and Hojdis, Nils and Kurz, Martin and Nawrocka-Herczynska, Monika}, title = {Funkeinheit und Vorrichtung mit einer Funkeinheit}, year = {2020}, abstract = {Dargestellt und beansprucht ist eine Funkeinheit mit einem Funkbauteil, einer elektrisch leitf{\"a}higen Antenne und einem Kunststoffverbindungsmittel. Das Funkbauteil weist einen Antennenanschluss auf. Das Kunststoffverbindungsmittel weist ein erstes Elastomermaterial mit elektrisch leitf{\"a}higem Zusatzmaterial auf, so dass das Kunststoffverbindungsmittel elektrisch leitf{\"a}hig ist. Das Kunststoffverbindungsmittel bildet eine mechanische und elektrisch leitf{\"a}hige Verbindung zwischen dem Antennenanschluss und der Antenne. Weiterhin wird eine Vorrichtung mit einem ein Matrixmaterial mit oder aus einem zweiten Elastomermaterial und einer Funkeinheit beschrieben und beansprucht, wobei die Funkeinheit vollst{\"a}ndig in das Matrixmaterial eingebettet ist. Die Vorrichtung kann insbesondere ein Fahrzeugreifen sein.}, language = {de} } @article{ElBerguiAbouabdillahBouriougetal.2023, author = {El Bergui, Omnia and Abouabdillah, Aziz and Bourioug, Mohamed and Schmitz, Dominik and Biel, Markus and Aboudrare, Abdellah and Krauss, Manuel and Jomaa, Ahlem and Romuli, Sebastian and M{\"u}ller, Joachim and Fagroud, Mustapha and Bouabid, Rachid}, title = {Innovative solutions for drought: Evaluating hydrogel application on onion cultivation (Allium cepa) in Morocco}, series = {Water}, volume = {15}, journal = {Water}, number = {11}, publisher = {MDPI}, address = {Basel}, doi = {10.3390/w15111972}, pages = {Artikel 1972}, year = {2023}, abstract = {Throughout the last decade, and particularly in 2022, water scarcity has become a critical concern in Morocco and other Mediterranean countries. The lack of rainfall during spring was worsened by a succession of heat waves during the summer. To address this drought, innovative solutions, including the use of new technologies such as hydrogels, will be essential to transform agriculture. This paper presents the findings of a study that evaluated the impact of hydrogel application on onion (Allium cepa) cultivation in Meknes, Morocco. The treatments investigated in this study comprised two different types of hydrogel-based soil additives (Arbovit® polyacrylate and Huminsorb® polyacrylate), applied at two rates (30 and 20 kg/ha), and irrigated at two levels of water supply (100\% and 50\% of daily crop evapotranspiration; ETc). Two control treatments were included, without hydrogel application and with both water amounts. The experiment was conducted in an open field using a completely randomized design. The results indicated a significant impact of both hydrogel-type dose and water dose on onion plant growth, as evidenced by various vegetation parameters. Among the hydrogels tested, Huminsorb® Polyacrylate produced the most favorable outcomes, with treatment T9 (100\%, HP, 30 kg/ha) yielding 70.55 t/ha; this represented an increase of 11 t/ha as compared to the 100\% ETc treatment without hydrogel application. Moreover, the combination of hydrogel application with 50\% ETc water stress showed promising results, with treatment T4 (HP, 30 kg, 50\%) producing almost the same yield as the 100\% ETc treatment without hydrogel while saving 208 mm of water.}, language = {en} } @article{ElMoussaouiTalbiAtmaneetal.2020, author = {El Moussaoui, Noureddine and Talbi, Sofian and Atmane, Ilyas and Kassmi, Khalil and Schwarzer, Klemens and Chayeb, Hamid and Bachiri, Najib}, title = {Feasibility of a new design of a Parabolic Trough Solar Thermal Cooker (PSTC)}, series = {Solar Energy}, volume = {201}, journal = {Solar Energy}, number = {Vol. 201 (May 2020)}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0038-092X}, doi = {10.1016/j.solener.2020.03.079}, pages = {866 -- 871}, year = {2020}, abstract = {In this article, we describe the structure, the functioning, and the tests of parabolic trough solar thermal cooker (PSTC). This oven is designed to meet the needs of rural residents, including Urban, which requires stable cooking temperatures above 200 °C. The cooking by this cooker is based on the concentration of the sun's rays on a glass vacuum tube and heating of the oil circulate in a big tube, located inside the glass tube. Through two small tubes, associated with large tube, the heated oil, rise and heats the pot of cooking pot containing the food to be cooked (capacity of 5 kg). This cooker is designed in Germany and extensively tested in Morocco for use by the inhabitants who use wood from forests. During a sunny day, having a maximum solar radiation around 720 W/m2 and temperature ambient around 26 °C, maximum temperatures recorded of the small tube, the large tube and the center of the pot are respectively: 370 °C, 270 °C and 260 °C. The cooking process with food at high (fries, ..), we show that the cooking oil temperature rises to 200 °C, after 1 h of heating, the cooking is done at a temperature of 120 °C for 20 min. These temperatures are practically stable following variations and decreases in the intensity of irradiance during the day. The comparison of these results with those of the literature shows an improvement of 30-50 \% on the maximum value of the temperature with a heat storage that could reach 60 min of autonomy. All the results obtained show the good functioning of the PSTC and the feasibility of cooking food at high temperature (>200 °C).}, language = {en} } @article{Elbers1993, author = {Elbers, Gereon}, title = {Messung von Ruß in der Außenluft - Praktische Erfahrungen und Meßergebnisse aus NRW}, series = {Aktuelle Aufgaben der Messtechnik in der Luftreinhaltung : Kolloquium Heidelberg, 2. bis 4. Juni 1993 / Kommission Reinhaltung der Luft im VDI und DIN}, journal = {Aktuelle Aufgaben der Messtechnik in der Luftreinhaltung : Kolloquium Heidelberg, 2. bis 4. Juni 1993 / Kommission Reinhaltung der Luft im VDI und DIN}, publisher = {VDI-Verl.}, address = {D{\"u}sseldorf}, isbn = {3-18-091059-3}, pages = {337}, year = {1993}, language = {de} } @book{Elbers2004, author = {Elbers, Gereon}, title = {Entwicklung eines Schnellmessverfahrens zur Charakterisierung der Wirkung von Umweltschadstoffen auf Pflanzen mit der Nahinfrarot-Spektroskopie : Schlussbericht zum Forschungsvorhaben ; Vorhabensbezeichnung: Schnellmessverfahren zur Charakterisierung der Wirkung von Umweltschadstoffen ; Laufzeit des Vorhabens: 01.09.2002 bis 29.02.2004 ; Verl{\"a}ngerung der Laufzeit: 01.03.2004 bis 30.04.04 ; Berichtszeitraum: 01.09.2002 bis 30.04.2004 / Zuwendungsempf{\"a}nger: FH-Aachen, Abt. J{\"u}lich, FB Chemie und Biotechnik. Gereon Elbers}, publisher = {Fachhochschule Aachen}, address = {J{\"u}lich}, pages = {Online-Ressource (17 S., 85,3 KB)}, year = {2004}, language = {de} } @article{Elbers2009, author = {Elbers, Gereon}, title = {Identification of marker peptides in hair for discrimination with regard to species and breed / Koerner, Andrea ; Ring, Maike ; Fabry, Marlies ; Elbers, Gereon ; Moeller, Martin}, series = {Proceedings of the Aachen-Dresden International Textile Conference, 3rd, Aachen, Germany, Nov. 26-27, 2009}, journal = {Proceedings of the Aachen-Dresden International Textile Conference, 3rd, Aachen, Germany, Nov. 26-27, 2009}, publisher = {DWI}, address = {Aachen}, pages = {1 CD-ROM}, year = {2009}, language = {en} } @article{ElbersBauerBucketal.1994, author = {Elbers, Gereon and Bauer, H. D. and Buck, Manfred and Dahmann, D.}, title = {Rußmessungen am Arbeitsplatz und in der Außenluft - Vergleich zweier Meßmethoden / H.D. Bauer, M. Buck, D. Dahmann, G. Elbers, H.-H. Fricke}, series = {Staub, Reinhaltung der Luft : air quality control. 54 (1994)}, journal = {Staub, Reinhaltung der Luft : air quality control. 54 (1994)}, isbn = {0039-0771}, pages = {55}, year = {1994}, language = {de} } @article{ElbersBehnerRemmeetal.1986, author = {Elbers, Gereon and Behner, T. and Remme, S. and Prissok, F.}, title = {Interstitial Metal Impurities as a Possible Cause of Enhanced Reactivities / T. Behner, G. Elbers, S. Remme, F. Prissok, P. Stegger, and G. Lehmann}, series = {Berichte der Bunsen-Gesellschaft : physical chemistry, chemical physics. 90 (1986)}, journal = {Berichte der Bunsen-Gesellschaft : physical chemistry, chemical physics. 90 (1986)}, isbn = {0005-9021}, pages = {698}, year = {1986}, language = {en} } @article{ElbersBuck1992, author = {Elbers, Gereon and Buck, Manfred}, title = {Soot Concentration in Ambient Air / M. Buck, G. Elbers}, series = {Erd{\"o}l \& Kohle, Erdgas, Petrochemie : EKEP. 45 (1992)}, journal = {Erd{\"o}l \& Kohle, Erdgas, Petrochemie : EKEP. 45 (1992)}, isbn = {0014-0058}, pages = {219}, year = {1992}, language = {en} } @article{ElbersGaebHoffmannetal.2006, author = {Elbers, Gereon and G{\"a}b, Martina and Hoffmann, Katharina and Lobe, Melanie}, title = {NIR-spectroscopic investigation of foliage of ozone-stressed Fagus sylvatica trees / G{\"a}b, Martina ; Hoffmann, Katharina ; Lobe, Melanie ; Metzger, Rut ; Ooyen, Sven van ; Elbers, Gereon ; K{\"o}llner, Barbara}, series = {Journal of Forest Research. 11 (2006), H. 2}, journal = {Journal of Forest Research. 11 (2006), H. 2}, isbn = {1341-6979}, pages = {69 -- 75}, year = {2006}, language = {en} } @article{ElbersLehmann1985, author = {Elbers, Gereon and Lehmann, G.}, title = {Electron paramagnetic resonance of Vanadyl ion impurities in crystalline solids: A comment}, series = {Journal of Physics and Chemistry of Solids. 46 (1985), H. 6}, journal = {Journal of Physics and Chemistry of Solids. 46 (1985), H. 6}, isbn = {0022-3697}, pages = {761}, year = {1985}, language = {en} } @article{ElbersLehmann1985, author = {Elbers, Gereon and Lehmann, G.}, title = {Electron Paramagnetic Resonance and Optical Absorption Spectra of VO2+ in CsCl Single Crystals}, series = {Zeitschrift f{\"u}r Naturforschung / Section A, a journal of physical sciences. 40 (1985)}, journal = {Zeitschrift f{\"u}r Naturforschung / Section A, a journal of physical sciences. 40 (1985)}, isbn = {0932-0784}, pages = {511}, year = {1985}, language = {en} } @article{ElbersMuratyan1991, author = {Elbers, Gereon and Muratyan, Simone}, title = {Problematik verkehrsbezogener Außenluftmessungen von Partikeln (Dieselruß)}, series = {+ Krebserzeugende Stoffe in der Umwelt : Herkunft, Messung, Risiko, Minimierung ; Kolloquium Mannheim, 23. bis 25. April 1991 / Kommission Reinhaltung der Luft im VDI und DIN}, journal = {+ Krebserzeugende Stoffe in der Umwelt : Herkunft, Messung, Risiko, Minimierung ; Kolloquium Mannheim, 23. bis 25. April 1991 / Kommission Reinhaltung der Luft im VDI und DIN}, publisher = {VDI-Verl.}, address = {D{\"u}sseldorf}, isbn = {3-18-090888-2}, pages = {143}, year = {1991}, language = {de} } @article{ElbersNierenHoffmannetal.2008, author = {Elbers, Gereon and Nieren, Monika and Hoffmann, Katharina and G{\"a}b, Martina}, title = {Schnellerfassung der Wirkung von Luftschadstoffen auf Pflanzen mit der Nahinfrarotspektroskopie (NIRS). Untersuchung Ammoniak exponierter Gr{\"a}ser und Kr{\"a}uter / Nieren, Monika ; Hoffmann, Katharina ; G{\"a}b, Martina ; Ooyen, Sven van ; K{\"o}llner, Barbara ; Elbe}, series = {Immissionsschutz. 13 (2008), H. 2}, journal = {Immissionsschutz. 13 (2008), H. 2}, isbn = {1430-9262}, pages = {82 -- 90}, year = {2008}, language = {de} } @article{ElbersPfefferFrieseletal.1993, author = {Elbers, Gereon and Pfeffer, H.-U. and Friesel, J. and Beier, R.}, title = {Pilotuntersuchungen gem{\"a}ß dem Verordnungsentwurf nach \S 40, Abs. 2 des Bundesimmissionsschutzgesetzes / H.-U. Pfeffer, J. Friesel, G. Elbers, R. Beier, K. Ellermann}, series = {Drei Jahrzehnte Luftqualit{\"a}ts{\"u}berwachung : Vortr{\"a}ge und Berichte zum Kolloquium "Drei Jahrzehnte Luftqualit{\"a}ts{\"u}berwachung - Bilanz und Perspektiven" am 11. November 1993 in Essen / [Hrsg.: Landesanstalt f{\"u}r Immissionsschutz Nordrhein-Westfalen. Red. Bearb.: Robert Niesenhaus]}, journal = {Drei Jahrzehnte Luftqualit{\"a}ts{\"u}berwachung : Vortr{\"a}ge und Berichte zum Kolloquium "Drei Jahrzehnte Luftqualit{\"a}ts{\"u}berwachung - Bilanz und Perspektiven" am 11. November 1993 in Essen / [Hrsg.: Landesanstalt f{\"u}r Immissionsschutz Nordrhein-Westfalen. Red. Bearb.: Robert Niesenhaus]}, address = {Essen}, pages = {117}, year = {1993}, language = {de} } @article{ElbersPfefferFrieseletal.1995, author = {Elbers, Gereon and Pfeffer, Hans-Ulrich and Friesel, J{\"u}rgen and Beier, Reinhold}, title = {Air Pollution Monitoring in Street Canyons / Hans-Ulrich Pfeffer, J{\"u}rgen Friesel, Gereon Elbers, Reinhold Beier,}, series = {Transport and air pollution : proceedings ; 3rd international symposium, Palais des Papes, Avignon, France, 6 - 10 June 1994 = Transports et pollution de l'air / [Third International Symposium on Transport and Air Pollution]. Ed. by Robert Joumard. Organizer: French National Institute for Transport and Safety Research}, journal = {Transport and air pollution : proceedings ; 3rd international symposium, Palais des Papes, Avignon, France, 6 - 10 June 1994 = Transports et pollution de l'air / [Third International Symposium on Transport and Air Pollution]. Ed. by Robert Joumard. Organizer: French National Institute for Transport and Safety Research}, publisher = {Elsevier}, address = {Amsterdam}, pages = {IX, 337 S : graph. Darst.}, year = {1995}, language = {en} } @article{ElbersRemmeLehmann1986, author = {Elbers, Gereon and Remme, S. and Lehmann, G.}, title = {EPR of Cr3+ in Tris(acetylacetonato)gallium(III) Single Crystals}, series = {Inorganic Chemistry. 25 (1986)}, journal = {Inorganic Chemistry. 25 (1986)}, isbn = {0020-1669}, pages = {896 -- 897}, year = {1986}, language = {en} } @article{ElbersRemmeLehmann1987, author = {Elbers, Gereon and Remme, S. and Lehmann, G.}, title = {EPR and Optical Absorption of Cr3+ in CsCl and CsBr}, series = {Physica Status Solidi (B). 142 (1987), H. 2}, journal = {Physica Status Solidi (B). 142 (1987), H. 2}, isbn = {0031-8957}, pages = {367 -- 377}, year = {1987}, language = {en} } @article{ElbersRichter1994, author = {Elbers, Gereon and Richter, J.}, title = {Messung kraftfahrzeugbedingter Rußimmissionen}, series = {Staub, Reinhaltung der Luft : air quality control. 54 (1994)}, journal = {Staub, Reinhaltung der Luft : air quality control. 54 (1994)}, isbn = {0039-0771}, pages = {19}, year = {1994}, language = {de} } @article{ElbersThomzik1990, author = {Elbers, Gereon and Thomzik, Manfred}, title = {Das Entstehen geruchsintensiver schwefelhaltiger organischer Verbindungen in Lackierereien und M{\"o}glichkeiten zu deren Vermeidung}, series = {Aus der T{\"a}tigkeit der LIS / Landesanstalt f{\"u}r Immissionsschutz des Landes Nordrhein-Westfalen. 1989 (1990)}, journal = {Aus der T{\"a}tigkeit der LIS / Landesanstalt f{\"u}r Immissionsschutz des Landes Nordrhein-Westfalen. 1989 (1990)}, isbn = {0931-5497}, pages = {35}, year = {1990}, language = {de} } @article{ElbersZangBuck1990, author = {Elbers, Gereon and Zang, Thorsten and Buck, Manfred}, title = {Ruß-Immissionsmessungen im Einflußbereich des Kraftfahrzeugverkehrs}, series = {Staub, Reinhaltung der Luft : air quality control. 50 (1990)}, journal = {Staub, Reinhaltung der Luft : air quality control. 50 (1990)}, isbn = {0039-0771}, pages = {93}, year = {1990}, language = {de} } @inproceedings{EngelThieringerTippkoetter2016, author = {Engel, M. and Thieringer, J. and Tippk{\"o}tter, Nils}, title = {Microbial electrosynthesis for sustainable biobutanol production}, series = {New frontiers of biotech-processes (Himmelfahrtstagung) : 02-04 May 2016, Rhein-Mosel-Halle, Koblenz/Germany}, booktitle = {New frontiers of biotech-processes (Himmelfahrtstagung) : 02-04 May 2016, Rhein-Mosel-Halle, Koblenz/Germany}, publisher = {DECHEMA}, address = {Frankfurt am Main}, pages = {77 -- 78}, year = {2016}, language = {en} } @article{EngelBayerHoltmannetal.2019, author = {Engel, Mareike and Bayer, Hendrik and Holtmann, Dirk and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {Flavin secretion of Clostridium acetobutylicum in a bioelectrochemical system - Is an iron limitation involved?}, series = {Bioelectrochemistry}, journal = {Bioelectrochemistry}, number = {In Press, Accepted Manuscript}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1567-5394}, doi = {10.1016/j.bioelechem.2019.05.014}, year = {2019}, language = {en} } @article{EngelGemuendeHoltmannetal.2019, author = {Engel, Mareike and Gem{\"u}nde, Andre and Holtmann, Dirk and M{\"u}ller-Renno, Christine and Ziegler, Christiane and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {Clostridium acetobutylicum's connecting world: cell appendage formation in bioelectrochemical systems}, series = {ChemElectroChem}, journal = {ChemElectroChem}, number = {Accepted Article}, publisher = {Wiley}, address = {Weinheim}, issn = {2196-0216}, doi = {10.1002/celc.201901656}, year = {2019}, language = {en} } @article{EngelHoltmannUlberetal.2018, author = {Engel, Mareike and Holtmann, Dirk and Ulber, Roland and Tippk{\"o}tter, Nils}, title = {Increased Biobutanol Production by Mediator-Less Electro-Fermentation}, series = {Biotechnology Journal}, journal = {Biotechnology Journal}, number = {Volume 14, Issue 4}, publisher = {Wiley-VCH}, issn = {1860-7314}, doi = {10.1002/biot.201800514}, pages = {Artikel 1800514}, year = {2018}, abstract = {A future bio-economy should not only be based on renewable raw materials but also in the raise of carbon yields of existing production routes. Microbial electrochemical technologies are gaining increased attention for this purpose. In this study, the electro-fermentative production of biobutanol with C. acetobutylicum without the use of exogenous mediators is investigated regarding the medium composition and the reactor design. It is shown that the use of an optimized synthetic culture medium allows higher product concentrations, increased biofilm formation, and higher conductivities compared to a synthetic medium supplemented with yeast extract. Moreover, the optimization of the reactor system results in a doubling of the maximum product concentrations for fermentation products. When a working electrode is polarized at -600 mV vs. Ag/AgCl, a shift from butyrate to acetone and butanol production is induced. This leads to an increased final solvent yield of Yᴀᴃᴇ = 0.202 gg⁻¹ (control 0.103 gg⁻¹), which is also reflected in a higher carbon efficiency of 37.6\% compared to 23.3\% (control) as well as a fourfold decrease in simplified E-factor to 0.43. The results are promising for further development of biobutanol production in bioelectrochemical systems in order to fulfil the principles of Green Chemistry.}, language = {en} } @article{EveraersKarimiVarzanehFlecketal.2020, author = {Everaers, Ralf and Karimi-Varzaneh, Hossein Ali and Fleck, Franz and Hojdis, Nils and Svaneborg, Carsten}, title = {Kremer-Grest Models for Commodity Polymer Melts: Linking Theory, Experiment, and Simulation at the Kuhn Scale}, series = {Macromolecules}, volume = {53}, journal = {Macromolecules}, number = {6}, publisher = {ACS Publications}, address = {Washington, DC}, issn = {1520-5835}, doi = {10.1021/acs.macromol.9b02428}, pages = {1901 -- 1916}, year = {2020}, abstract = {The Kremer-Grest (KG) polymer model is a standard model for studying generic polymer properties in molecular dynamics simulations. It owes its popularity to its simplicity and computational efficiency, rather than its ability to represent specific polymers species and conditions. Here we show that by tuning the chain stiffness it is possible to adapt the KG model to model melts of real polymers. In particular, we provide mapping relations from KG to SI units for a wide range of commodity polymers. The connection between the experimental and the KG melts is made at the Kuhn scale, i.e., at the crossover from the chemistry-specific small scale to the universal large scale behavior. We expect Kuhn scale-mapped KG models to faithfully represent universal properties dominated by the large scale conformational statistics and dynamics of flexible polymers. In particular, we observe very good agreement between entanglement moduli of our KG models and the experimental moduli of the target polymers.}, language = {en} } @article{FalkenbergBottBongaertsetal.2022, author = {Falkenberg, Fabian and Bott, Michael and Bongaerts, Johannes and Siegert, Petra}, title = {Phylogenetic survey of the subtilase family and a data-mining-based search for new subtilisins from Bacillaceae}, series = {Frontiers in Microbiology}, volume = {2022}, journal = {Frontiers in Microbiology}, number = {13}, publisher = {Frontiers}, address = {Lausanne}, issn = {1664-302X}, doi = {10.3389/fmicb.2022.1017978}, pages = {Artikel 13:1017978}, year = {2022}, abstract = {The subtilase family (S8), a member of the clan SB of serine proteases are ubiquitous in all kingdoms of life and fulfil different physiological functions. Subtilases are divided in several groups and especially subtilisins are of interest as they are used in various industrial sectors. Therefore, we searched for new subtilisin sequences of the family Bacillaceae using a data mining approach. The obtained 1,400 sequences were phylogenetically classified in the context of the subtilase family. This required an updated comprehensive overview of the different groups within this family. To fill this gap, we conducted a phylogenetic survey of the S8 family with characterised holotypes derived from the MEROPS database. The analysis revealed the presence of eight previously uncharacterised groups and 13 subgroups within the S8 family. The sequences that emerged from the data mining with the set filter parameters were mainly assigned to the subtilisin subgroups of true subtilisins, high-alkaline subtilisins, and phylogenetically intermediate subtilisins and represent an excellent source for new subtilisin candidates.}, language = {en} } @article{FengSeiblerAlamietal.1999, author = {Feng, Yong-Qing and Seibler, Jost and Alami, Raouf and Eisen, Andrew and Westerman, Karen A. and Leboulch, Philippe and Fiering, Steven and Bouhassira, Eric E.}, title = {Site-specific chromosomal integration in mammalian cells: highly efficient CRE recombinase-mediated cassette exchange}, series = {Journal of Molecular Biology}, volume = {292}, journal = {Journal of Molecular Biology}, number = {4}, issn = {0022-2836}, doi = {10.1006/jmbi.1999.3113}, pages = {779 -- 785}, year = {1999}, language = {en} } @article{Feuerriegel2001, author = {Feuerriegel, Uwe}, title = {Trennen und Trocknen. FH Aachen verf{\"u}gt {\"u}ber einen Zentrifugentrockner im Technikumsmaßstab}, series = {Lebensmitteltechnik. 33 (2001), H. 7-8}, journal = {Lebensmitteltechnik. 33 (2001), H. 7-8}, isbn = {0047-4290}, pages = {22 -- 23}, year = {2001}, language = {de} } @book{Feuerriegel1993, author = {Feuerriegel, Uwe}, title = {Zur Desaktivierung eines Desaktivierung eines Palladium-Tr{\"a}gerkatalysators durch Schwefel¬wasserstoff bei der katalytischen Methanoxidation}, publisher = {Univ.-Gesamthochsch.}, address = {Kassel}, pages = {128 S.: graph. Darst.}, year = {1993}, language = {de} } @article{Feuerriegel1998, author = {Feuerriegel, Uwe}, title = {Energetische Verwertung von Kunststoffabf{\"a}llen}, series = {Chemie und Technologie makromolekularer Stoffe :, 16. Kolloquium. / Fachhochschule / Fachbereich Chemieingenieurwesen. 20. November 1998 an der FH Aachen, Fachbereich Chemieingenieurwesen}, journal = {Chemie und Technologie makromolekularer Stoffe :, 16. Kolloquium. / Fachhochschule / Fachbereich Chemieingenieurwesen. 20. November 1998 an der FH Aachen, Fachbereich Chemieingenieurwesen}, publisher = {Fachhochschule Aachen}, address = {Aachen}, pages = {169 -- 189}, year = {1998}, language = {de} } @book{Feuerriegel2016, author = {Feuerriegel, Uwe}, title = {Verfahrenstechnik mit EXCEL: Verfahrenstechnische Berechnungen effektiv durchf{\"u}hren und professionell dokumentieren}, publisher = {Springer Fachmedien}, address = {Wiesbaden}, isbn = {978-3-658-02902-9}, doi = {10.1007/978-3-658-02903-6}, pages = {XVII, 381 Seiten}, year = {2016}, language = {de} } @article{FeuerriegelHoffmannWalenziketal.2001, author = {Feuerriegel, Uwe and Hoffmann, Ulrich and Walenzik, C. and K{\"o}gel, J.}, title = {F{\"u}r Scale-up´s und Betriebsmuster, Projekt Trocknungstechnik an der FH Aachen}, series = {CITplus : das Praxismagazin f{\"u}r Verfahrenstechnik und Apparatebau. 4 (2001)}, journal = {CITplus : das Praxismagazin f{\"u}r Verfahrenstechnik und Apparatebau. 4 (2001)}, isbn = {1436-2597}, pages = {24 -- 25}, year = {2001}, language = {de} } @article{FeuerriegelKlose1993, author = {Feuerriegel, Uwe and Klose, W.}, title = {Reaktionskinetik der katalytischen Methan-Oxidation und experimentelle Untersuchungen zur Desaktivierung eines Palladium-Tr{\"a}gerkatalysators durch Schwefelwasserstoff. Klose, W. ; Feuerriegel, U.}, series = {Chemie - Ingenieur - Technik. 65 (1993), H. 10}, journal = {Chemie - Ingenieur - Technik. 65 (1993), H. 10}, isbn = {0009-286X}, pages = {1242 -- 1243}, year = {1993}, language = {de} } @article{FeuerriegelKlose1998, author = {Feuerriegel, Uwe and Klose, W.}, title = {Untersuchungen zum Mechanismus der Desaktivierung eines Palladium-Tr{\"a}gerkatalysators durch Vergiftung mit Schwefelwasserstoff}, series = {Chemie - Ingenieur - Technik. 70 (1998), H. 4}, journal = {Chemie - Ingenieur - Technik. 70 (1998), H. 4}, isbn = {0009-286X}, pages = {449 -- 452}, year = {1998}, language = {de} } @article{FeuerriegelKlose1998, author = {Feuerriegel, Uwe and Klose, W.}, title = {Investigations into the Mechanism of the Deactivation of a Palladium-Supported Catalyst by Hydrogen Sulfide Poisoning. Klose, W. ; Feuerriegel, U.}, series = {Chemical engineering \& technology. 21 (1998), H. 7}, journal = {Chemical engineering \& technology. 21 (1998), H. 7}, isbn = {0930-7516}, pages = {562 -- 564}, year = {1998}, language = {en} } @article{FeuerriegelKloseSloboshaninetal.1994, author = {Feuerriegel, Uwe and Klose, W. and Sloboshanin, S. and Goebel, H. [u.a.]}, title = {Deactivation of a palladium-supported alumina catalyst by hydrogen sulfide during the oxidation of methane}, series = {Langmuir: the ACS journal of surfaces and colloids. 10 (1994), H. 10}, journal = {Langmuir: the ACS journal of surfaces and colloids. 10 (1994), H. 10}, isbn = {0743-74363}, pages = {3567 -- 3570}, year = {1994}, language = {en} } @article{FeuerriegelKuenschStahlbergetal.1994, author = {Feuerriegel, Uwe and K{\"u}nsch, M. and Stahlberg, R. and Steiger, F.}, title = {Massen- und Energiebilanz des Thermoselect-Verfahrens}, series = {Thermoselect-Verfahren zur Ent- und Vergasung von Abf{\"a}llen / Franz J. Schweitzer [Hrsg.]}, journal = {Thermoselect-Verfahren zur Ent- und Vergasung von Abf{\"a}llen / Franz J. Schweitzer [Hrsg.]}, publisher = {EF-Verl. f{\"u}r Energie- u. Umwelttechnik}, address = {Berlin}, isbn = {3-924511-47-0}, pages = {207 S. : graph. Darst.}, year = {1994}, language = {de} } @article{FeuerriegelMaHoffmann1990, author = {Feuerriegel, Uwe and Ma, J. and Hoffmann, U.}, title = {Untersuchungen zur Rußfilterregeneration mit Hilfe von Z{\"u}ndhilfen. Ma, J.; Hoffmann, U.; Feuerriegel, U}, series = {Erd{\"o}l und Kohle - Erdgas, Brennstoff-Chemie. 43 (1990)}, journal = {Erd{\"o}l und Kohle - Erdgas, Brennstoff-Chemie. 43 (1990)}, isbn = {0014-0058}, pages = {150 -- 157}, year = {1990}, language = {de} } @article{FeuerriegelStahlberg1995, author = {Feuerriegel, Uwe and Stahlberg, R.}, title = {Thermoselect - Energie- und Rohstoffgewinnung, Verfahrensgrundlagen zur unterbrechungslosen Verwertung von Restabf{\"a}llen. Stahlberg, R.; Feuerriegel, U.}, series = {Thermoselect : der neue Weg, Restm{\"u}ll umweltgerecht zu behandeln ; [Tagungsband zur Fachtagung Thermoselect am 19. Januar 1995 in Rastatt/Baden] / G{\"u}nther H{\"a}ßler. 2. durchges. und erw. Aufl.}, journal = {Thermoselect : der neue Weg, Restm{\"u}ll umweltgerecht zu behandeln ; [Tagungsband zur Fachtagung Thermoselect am 19. Januar 1995 in Rastatt/Baden] / G{\"u}nther H{\"a}ßler. 2. durchges. und erw. Aufl.}, publisher = {Goerner}, address = {Karlsruhe}, isbn = {3-9803665-4-5}, pages = {13 -- 32}, year = {1995}, language = {de} } @article{FeuerriegelStahlberg1995, author = {Feuerriegel, Uwe and Stahlberg, R.}, title = {Untersuchungen an der Thermoselect-Anlage Fondotoce (Italien), Qualit{\"a}ten der Produkte und Nachweis der Verteilung der chemischen Elemente in den Stoffstr{\"o}men. Stahlberg, R.; Feuerriegel, U.}, series = {Thermoselect : der neue Weg, Restm{\"u}ll umweltgerecht zu behandeln ; [Tagungsband zur Fachtagung Thermoselect am 19. Januar 1995 in Rastatt/Baden] / G{\"u}nther H{\"a}ßler. 2. durchges. und erw. Aufl.}, journal = {Thermoselect : der neue Weg, Restm{\"u}ll umweltgerecht zu behandeln ; [Tagungsband zur Fachtagung Thermoselect am 19. Januar 1995 in Rastatt/Baden] / G{\"u}nther H{\"a}ßler. 2. durchges. und erw. Aufl.}, publisher = {Goerner}, address = {Karlsruhe}, isbn = {3-9803665-4-5}, pages = {33 -- 54}, year = {1995}, language = {de} } @article{FeuerriegelStahlberg1995, author = {Feuerriegel, Uwe and Stahlberg, R.}, title = {Thermoselect - Energie- und Rohstoffgewinnung. Stahlberg, R. ; Feuerriegel, U.}, series = {Abfallwirtschaft Stoffkreisl{\"a}ufe / Terratec '95, Kongress West-Ost-Transfer Umwelt vom 1. bis 3. M{\"a}rz 1995. Leipziger Messe. Hrsg. von Hasso Scheffler ...}, journal = {Abfallwirtschaft Stoffkreisl{\"a}ufe / Terratec '95, Kongress West-Ost-Transfer Umwelt vom 1. bis 3. M{\"a}rz 1995. Leipziger Messe. Hrsg. von Hasso Scheffler ...}, publisher = {Teubner}, address = {Stuttgart [u.a.]}, isbn = {3-8154-3513-7}, pages = {179 -- 194}, year = {1995}, language = {de} }