@article{YoshinobuIwasakiUietal.2005, author = {Yoshinobu, T. and Iwasaki, H. and Ui, Y. and Furuichi, K. and Ermelenko, Y. and Mourzina, Y. and Wagner, Torsten and N{\"a}ther, Niko and Sch{\"o}ning, Michael Josef}, title = {The light-addressable potentiometric sensor for multi-ion sensing and imaging}, series = {Methods. 37 (2005), H. 1}, journal = {Methods. 37 (2005), H. 1}, isbn = {1046-2023}, pages = {99 -- 102}, year = {2005}, language = {en} } @article{YoshinobuErmelenkoMourzinaetal.2003, author = {Yoshinobu, T. and Ermelenko, Y. and Mourzina, Y. and Sch{\"o}ning, Michael Josef and Iwasaki, H. and Vlasov, Y.}, title = {Multi-component analysis based on the light-addressable potentiometric sensor (LAPS)}, series = {Proceedings : 11th international conference Sensor 2003; 13 - 15 May 2003, Exhibition Centre Nuremberg, Germany}, journal = {Proceedings : 11th international conference Sensor 2003; 13 - 15 May 2003, Exhibition Centre Nuremberg, Germany}, publisher = {AMA Service}, address = {Wunstorf}, pages = {141 -- 144}, year = {2003}, language = {en} } @article{YoshinobuEckenPoghossianetal.2001, author = {Yoshinobu, T. and Ecken, H. and Poghossian, Arshak and Simonis, A. and Iwasaki, H. and L{\"u}th, H. and Sch{\"o}ning, Michael Josef}, title = {Constant-current-mode LAPS (CLAPS) for the detection of penicillin}, series = {Electroanalysis. 13 (2001), H. 8-9}, journal = {Electroanalysis. 13 (2001), H. 8-9}, isbn = {1040-0397}, pages = {733 -- 736}, year = {2001}, language = {en} } @article{YoshinobuEckenPoghossianetal.2001, author = {Yoshinobu, T. and Ecken, H. and Poghossian, Arshak and L{\"u}th, H. and Iwasaki, H. and Sch{\"o}ning, Michael Josef}, title = {Alternative sensor materials for light-addressable potentiometric sensors}, series = {Sensors and Actuators B. 76 (2001), H. 1-3}, journal = {Sensors and Actuators B. 76 (2001), H. 1-3}, isbn = {0925-4005}, pages = {388 -- 392}, year = {2001}, language = {en} } @article{YoshinobuEckenIsmailetal.2001, author = {Yoshinobu, T. and Ecken, H. and Ismail, Md.A.B. and Iwasaki, H. and L{\"u}th, H. and Sch{\"o}ning, Michael Josef}, title = {Chemical imaging sensor and its application to biological systems}, series = {Scaling down in electrochemistry : electrochemical micro- and nanosystem technology ; proceedings of the 3rd International Symposium on Electrochemical Microsystem Technologies, Garmisch-Patenkirchen, Germany, 11 - 15 September 2000 / ed. by J. W. Schultz}, journal = {Scaling down in electrochemistry : electrochemical micro- and nanosystem technology ; proceedings of the 3rd International Symposium on Electrochemical Microsystem Technologies, Garmisch-Patenkirchen, Germany, 11 - 15 September 2000 / ed. by J. W. Schultz}, publisher = {Elsevier [u.a.]}, address = {Amsterdam [u.a.]}, isbn = {0-08-044014-2}, pages = {259 -- 263}, year = {2001}, language = {en} } @article{YazdanbakhshSolbachBitz2012, author = {Yazdanbakhsh, Pedram and Solbach, Klaus and Bitz, Andreas}, title = {Variable power combiner for RF mode shimming in 7-T MR imaging}, series = {IEEE Transaction on Biomedical Engineering}, volume = {59}, journal = {IEEE Transaction on Biomedical Engineering}, number = {9}, publisher = {IEEE}, address = {New York}, issn = {1558-2531}, doi = {10.1109/TBME.2012.2205926}, pages = {2549 -- 2557}, year = {2012}, abstract = {This contribution discusses the utilization of RF power in an MRI system with RF mode shimming which enables the superposition of circularly polarized modes of a transmit RF coil array driven by a Butler matrix. Since the required power for the individual modes can vary widely, mode-shimming can result in a significant underutilization of the total available RF power. A variable power combiner (VPC) is proposed to improve the power utilization: it can be realized as a reconfiguration of the MRI transmit system by the inclusion of one additional matrix network which receives the power from all transmit amplifiers at its input ports and provides any desired (combined) power distribution at its output ports by controlling the phase and amplitude of the amplifiers' input signals. The power distribution at the output ports of the VPC is then fed into the "mode" ports of the coil array Butler matrix in order to superimpose the spatial modes at the highest achievable power utilization. The VPC configuration is compared to the standard configuration of the transmit chain of our MRI system with 8 transmit channels and 16 coils. In realistic scenarios, improved power utilization was achieved from 17\% to 60\% and from 14\% to 55\% for an elliptical phantom and a region of interest in the abdomen, respectively, and an increase of the power utilization of 1 dB for a region of interest in the upper leg. In general, it is found that the VPC allows significant improvement in power utilization when the shimming solution demands only a few modes to be energized, while the technique can yield loss in power utilization in cases with many modes required at high power level.}, language = {en} } @article{YangKriechbaumerAlbrachtetal.2015, author = {Yang, Peng-Fei and Kriechbaumer, Andreas and Albracht, Kirsten and Sanno, Maximilian and Ganse, Bergita and Koy, Timmo and Shang, Peng and Br{\"u}ggemann, Gert-Peter and M{\"u}ller, Lars Peter and Rittweger, J{\"o}rn}, title = {On the relationship between tibia torsional deformation and regional muscle contractions in habitual human exercises in vivo}, series = {Journal of Biomechanics}, volume = {48}, journal = {Journal of Biomechanics}, number = {3}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0021-9290}, doi = {10.1016/j.jbiomech.2014.12.031}, pages = {456 -- 464}, year = {2015}, language = {en} } @article{YangKriechbaumerAlbrachtetal.2014, author = {Yang, Peng-Fei and Kriechbaumer, Andreas and Albracht, Kirsten and Sanno, Maximilian and Ganse, Bergita and Koy, Timmo and Shang, Peng and br{\"u}ggemann, Gert-Peter and M{\"u}ller, Lars Peter and Rittweger, J{\"o}rn}, title = {A novel optical approach for assessing in vivo bone segment deformation and its application in muscle-bone relationship studies in humans}, series = {Journal of Orthopaedic Translation}, volume = {2}, journal = {Journal of Orthopaedic Translation}, number = {4}, publisher = {Elsevier}, address = {Singapore}, issn = {2214-0328}, doi = {10.1016/j.jot.2014.07.078}, pages = {238 -- 238}, year = {2014}, language = {en} } @inproceedings{XuSchwarteHeinoletal.1998, author = {Xu, Zhanping and Schwarte, Rudolf and Heinol, Horst-Guenther and Buxbaum, Bernd and Ringbeck, Thorsten}, title = {Smart pixel : photonic mixer device (PMD) ; new system concept of a 3D-imaging camera-on-a-chip}, series = {Proceedings : M2VIP '98; Nanjing, China, 10th - 12th September 1998}, booktitle = {Proceedings : M2VIP '98; Nanjing, China, 10th - 12th September 1998}, editor = {Cheung, Edmund H. M.}, address = {Hong Kong}, isbn = {962-442-129-3}, pages = {259 -- 264}, year = {1998}, language = {en} } @article{XuLueMaetal.2005, author = {Xu, Jung-Ming and L{\"u}, Min and Ma, Meijie and Hellwig, Angelika}, title = {Super connectivity of line graphs}, series = {Information processing letters}, volume = {Vol. 94}, journal = {Information processing letters}, number = {Iss. 4}, issn = {1872-6119 (E-Journal); 0020-0190 (Print)}, pages = {191 -- 195}, year = {2005}, language = {en} } @article{WulfhorstDuweMerseburgetal.2016, author = {Wulfhorst, Helene and Duwe, Anna-Maria and Merseburg, Johannes and Tippk{\"o}tter, Nils}, title = {Compositional analysis of pretreated (beech) wood using differential scanning calorimetry and multivariate data analysis}, series = {Tetrahedron}, volume = {72}, journal = {Tetrahedron}, number = {46}, publisher = {Elsevier}, address = {Amsterdam}, doi = {10.1016/j.tet.2016.04.029}, pages = {7329 -- 7334}, year = {2016}, abstract = {The composition of plant biomass varies depending on the feedstock and pre-treatment conditions and influences its processing in biorefineries. In order to ensure optimal process conditions, the quantitative proportion of the main polymeric components of the pre-treated biomass has to be determined. Current standard procedures for biomass compositional analysis are complex, the measurements are afflicted with errors and therefore often not comparable. Hence, new powerful analytical methods are urgently required to characterize biomass. In this contribution, Differential Scanning Calorimetry (DSC) was applied in combination with multivariate data analysis (MVA) to detect the cellulose content of the plant biomass pretreated by Liquid Hot Water (LHW) and Organosolv processes under various conditions. Unlike conventional techniques, the developed analytic method enables the accurate quantification of monosaccharide content of the plant biomass without any previous sample preparation. It is easy to handle and avoids errors in sample preparation.}, language = {en} } @inproceedings{WulfhorstDuweMoehringetal.2016, author = {Wulfhorst, H. and Duwe, A. and M{\"o}hring, S. and Jurca, O. and Tippk{\"o}tter, Nils}, title = {Analysis of pretreated biomass by differential scanning 132 calorimetry and multivariate data analysis}, series = {New frontiers of biotech-processes (Himmelfahrtstagung) : 02-04 May 2016, Rhein-Mosel-Halle, Koblenz/Germany}, booktitle = {New frontiers of biotech-processes (Himmelfahrtstagung) : 02-04 May 2016, Rhein-Mosel-Halle, Koblenz/Germany}, publisher = {DECHEMA}, address = {Frankfurt am Main}, pages = {132}, year = {2016}, language = {en} } @inproceedings{WuKemper2016, author = {Wu, Ziyi and Kemper, Hans}, title = {The optimal 48 V - battery pack for a specific load profile of a heavy duty vehicle}, series = {8. Internationale Fachtagung Kraftwerk Batterie : 26. - 27. April 2016, M{\"u}nster, Deutschland}, booktitle = {8. Internationale Fachtagung Kraftwerk Batterie : 26. - 27. April 2016, M{\"u}nster, Deutschland}, year = {2016}, language = {en} } @inproceedings{WuPoghossianWerneretal.2013, author = {Wu, Chunsheng and Poghossian, Arshak and Werner, Frederik and Bronder, Thomas and B{\"a}cker, Matthias and Wang, Ping and Sch{\"o}ning, Michael Josef}, title = {An application of a scanning light-addressable potentiometric sensor for label-free DNA detection}, series = {11. Dresdner Sensor-Symposium : 9.-11.12.2013}, booktitle = {11. Dresdner Sensor-Symposium : 9.-11.12.2013}, organization = {Dresdner Sensor-Symposium <11, 2013>}, isbn = {978-3-9813484-5-3}, pages = {164 -- 168}, year = {2013}, language = {en} } @article{WuPoghossianBronderetal.2016, author = {Wu, Chunsheng and Poghossian, Arshak and Bronder, Thomas and Sch{\"o}ning, Michael Josef}, title = {Sensing of double-stranded DNA molecules by their intrinsic molecular charge using the light-addressable potentiometric sensor}, series = {Sensors and Actuators B: Chemical}, journal = {Sensors and Actuators B: Chemical}, number = {229}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2016.02.004}, pages = {506 -- 512}, year = {2016}, abstract = {A multi-spot light-addressable potentiometric sensor (LAPS), which belongs to the family of semiconductor field-effect devices, was applied for label-free detection of double-stranded deoxyribonucleic acid (dsDNA) molecules by their intrinsic molecular charge. To reduce the distance between the DNA charge and sensor surface and thus, to enhance the electrostatic coupling between the dsDNA molecules and the LAPS, the negatively charged dsDNA molecules were electrostatically adsorbed onto the gate surface of the LAPS covered with a positively charged weak polyelectrolyte layer of PAH (poly(allylamine hydrochloride)). The surface potential changes in each spot of the LAPS, induced by the layer-by-layer adsorption of a PAH/dsDNA bilayer, were recorded by means of photocurrent-voltage and constant-photocurrent measurements. In addition, the surface morphology of the gate surface before and after consecutive electrostatic adsorption of PAH and dsDNA layers was studied by atomic force microscopy measurements. Moreover, fluorescence microscopy was used to verify the successful adsorption of dsDNA molecules onto the PAH-modified LAPS surface. A high sensor signal of 25 mV was registered after adsorption of 10 nM dsDNA molecules. The lower detection limit is down to 0.1 nM dsDNA. The obtained results demonstrate that the PAH-modified LAPS device provides a convenient and rapid platform for the direct label-free electrical detection of in-solution hybridized dsDNA molecules.}, language = {en} } @article{WuBronderPoghossianetal.2015, author = {Wu, Chunsheng and Bronder, Thomas and Poghossian, Arshak and Werner, Frederik and Sch{\"o}ning, Michael Josef}, title = {Label-free detection of DNA using light-addressable potentiometric sensor modified with a positively charged polyelectrolyte layer}, series = {Nanoscale}, volume = {14}, journal = {Nanoscale}, number = {7}, publisher = {Royal Society of Chemistry (RSC)}, address = {Cambridge}, doi = {10.1039/C4NR07225A}, pages = {6143 -- 6150}, year = {2015}, abstract = {A multi-spot (16 spots) light-addressable potentiometric sensor (MLAPS) consisting of an Al-p-Si-SiO2 structure modified with a weak polyelectrolyte layer of PAH (poly(allylamine hydrochloride)) was applied for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge for the first time. To achieve a preferentially flat orientation of DNA strands and thus, to reduce the distance between the DNA charge and MLAPS surface, the negatively charged probe single-stranded DNAs (ssDNA) were electrostatically adsorbed onto the positively charged PAH layer using a simple layer-by-layer (LbL) technique. In this way, more DNA charge can be positioned within the Debye length, yielding a higher sensor signal. The surface potential changes in each spot induced due to the surface modification steps (PAH adsorption, probe ssDNA immobilization, hybridization with complementary target DNA (cDNA), non-specific adsorption of mismatched ssDNA) were determined from the shifts of photocurrent-voltage curves along the voltage axis. A high sensor signal of 83 mV was registered after immobilization of probe ssDNA onto the PAH layer. The hybridization signal increases from 5 mV to 32 mV with increasing the concentration of cDNA from 0.1 nM to 5 μM. In contrast, a small signal of 5 mV was recorded in the case of non-specific adsorption of fully mismatched ssDNA (5 μM). The obtained results demonstrate the potential of the MLAPS in combination with the simple and rapid LbL immobilization technique as a promising platform for the future development of multi-spot light-addressable label-free DNA chips with direct electrical readout.}, language = {en} } @article{WuBronderPoghossianetal.2014, author = {Wu, Chunsheng and Bronder, Thomas and Poghossian, Arshak and Werner, Frederik and B{\"a}cker, Matthias and Sch{\"o}ning, Michael Josef}, title = {Label-free electrical detection of DNA with a multi-spot LAPS: First step towards light-addressable DNA chips}, series = {Physica status solidi A : Applications and materials science}, volume = {211}, journal = {Physica status solidi A : Applications and materials science}, number = {6}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)}, doi = {10.1002/pssa.201330442}, pages = {1423 -- 1428}, year = {2014}, abstract = {A multi-spot (4 × 4 spots) light-addressable potentiometric sensor (MLAPS) consisting of an Al-p-Si-SiO2 structure has been applied for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge for the first time. Single-stranded probe ssDNA molecules (20 bases) were covalently immobilized onto the silanized SiO2 gate surface. The unspecific adsorption of mismatch ssDNA on the MLAPS gate surface was blocked by bovine serum albumin molecules. To reduce the screening effect and to achieve a high sensor signal, the measurements were performed in a low ionic-strength solution. The photocurrent-voltage (I-V) curves were simultaneously recorded on all 16 spots after each surface functionalization step. Large shifts of I-V curves of 25 mV were registered after the DNA immobilization and hybridization event. In contrast, a small potential shift (∼5 mV) was observed in case of mismatch ssDNA, revealing good specificity of the sensor. The obtained results demonstrate the potential of the MLAPS as promising transducer platform for the multi-spot label-free electrical detection of DNA molecules by their intrinsic molecular charge.}, language = {en} } @inproceedings{WuBronderPoghossianetal.2014, author = {Wu, Chunsheng and Bronder, Thomas and Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {DNA-hybridization detection using light-addressable potentiometric sensor modified with gold layer}, series = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)}, booktitle = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)}, publisher = {VDE-Verl.}, address = {D{\"u}sseldorf}, organization = {VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik}, isbn = {978-3-8007-3622-5}, pages = {1 -- 4}, year = {2014}, language = {en} } @article{Wrede1996, author = {Wrede, Oliver}, title = {Mnemotechnik in graphischen Benutzeroberfl{\"a}chen}, series = {Form / Form-Diskurs : Zeitschrift f{\"u}r Design und Theorie. 1 (1996), H. 2}, journal = {Form / Form-Diskurs : Zeitschrift f{\"u}r Design und Theorie. 1 (1996), H. 2}, year = {1996}, language = {en} } @article{Wrede2016, author = {Wrede, Oliver}, title = {Continuity in travel information}, series = {Information Design Journal}, volume = {22}, journal = {Information Design Journal}, number = {2}, publisher = {John Benjamins}, address = {Amsterdam}, issn = {0142-5471}, doi = {10.1075/idj.22.2.09wre}, pages = {172 -- 178}, year = {2016}, abstract = {This article discusses the contrast between the information transportation companies provide to travellers and that of their brand messaging. Companies' brand messaging often portrays the service they provide as pleasant, stress free and perfect. Customers and users of the service, on the other hand, often describe their experience of the service as a negative one. This article suggests that the brand value would be greater if transportation companies paid more attention to the users' experience when designing their information systems, particularly in worst case scenarios.}, language = {en} } @book{WosnitzaHilgers2012, author = {Wosnitza, Franz and Hilgers, Hans Gerd}, title = {Energieeffizienz und Energiemanagement : ein {\"U}berblick heutiger M{\"o}glichkeiten und Notwendigkeiten}, publisher = {Springer Spektrum}, address = {Wiesbaden}, isbn = {978-3-8348-1941-3}, pages = {XVII, 548 S. : Ill., graph. Darst.}, year = {2012}, language = {en} } @inproceedings{WollertPlessmann1993, author = {Wollert, J{\"o}rg and Plessmann, K. W.}, title = {Controlling processes by operating-point based hybride observers}, series = {EUFIT '93 : September 7 - 10, 1993, Eurogress Aachen, Germany, proceedings / First European Congress on Fuzzy and Intelligent Technologies}, booktitle = {EUFIT '93 : September 7 - 10, 1993, Eurogress Aachen, Germany, proceedings / First European Congress on Fuzzy and Intelligent Technologies}, publisher = {Verl. d. Augustinus Buchh.}, address = {Aachen}, organization = {EUFIT <1, 1993, Aachen>}, isbn = {3-86073-176-9}, pages = {1151 -- 1155}, year = {1993}, language = {en} } @inproceedings{Wollert2012, author = {Wollert, J{\"o}rg}, title = {The performance of UWB-communication in an industrial environment}, series = {IEEE 1st International Symposium on Wireless Systems : (IDAACS-SWS) : Offenburg, 20-21 Sept. 2012}, booktitle = {IEEE 1st International Symposium on Wireless Systems : (IDAACS-SWS) : Offenburg, 20-21 Sept. 2012}, publisher = {IEEE}, address = {Piscataway, NJ}, organization = {International Symposium on Wireless Systems <1, 2012, Offenburg>}, isbn = {978-1-4673-4678-8}, doi = {10.1109/IDAACS-SWS.2012.6377639}, pages = {85 -- 90}, year = {2012}, language = {en} } @inproceedings{Wollert2015, author = {Wollert, J{\"o}rg}, title = {Wireless systems for machinery safety : Requirements and solutions for wireless real time systems}, series = {16th International Conference on Research and Education in Mechatronics (REM), 2015}, booktitle = {16th International Conference on Research and Education in Mechatronics (REM), 2015}, isbn = {978-3-945728-01-7}, doi = {10.1109/REM.2015.7380377}, pages = {88 -- 91}, year = {2015}, language = {en} } @article{WollbrinkMasloZimmeretal.2020, author = {Wollbrink, Moritz and Maslo, Semir and Zimmer, Daniel and Abbas, Karim and Arntz, Kristian and Bergs, Thomas}, title = {Clamping and substrate plate system for continuous additive build-up and post-processing of metal parts}, series = {Procedia CIRP}, volume = {93}, journal = {Procedia CIRP}, publisher = {Elsevier}, address = {Amsterdam}, issn = {2212-8271}, doi = {10.1016/j.procir.2020.04.015}, pages = {108 -- 113}, year = {2020}, abstract = {The manufacturing share of laser powder bed fusion (L-PBF) increases in industrial application, but still many process steps are manually operated. Additionally, it is not possible to achieve tight dimensional tolerances or low surfaces roughness. Hence, a process chain has to be set up to combine additive manufacturing (AM) with further machining technologies. To achieve a continuous workpiece flow as basis for further industrialization of L-PBF, the paper presents a novel substrate system and its application on L-PBF machines and post-processing. The substrate system consists of a zero-point clamping system and a matrix-like interface of contact pins to be substantially connected to the workpiece within the L-PBF process.}, language = {en} } @article{WoliszSchuetzBlankeetal.2017, author = {Wolisz, Henryk and Sch{\"u}tz, Thomas and Blanke, Tobias and Hagenkamp, Markus and Kohrn, Markus and Wesseling, Mark and M{\"u}ller, Dirk}, title = {Cost optimal sizing of smart buildings' energy system components considering changing end-consumer electricity markets}, series = {Energy}, volume = {137}, journal = {Energy}, publisher = {Elsevier}, address = {Amsterdam}, doi = {10.1016/j.energy.2017.06.025}, pages = {715 -- 728}, year = {2017}, language = {en} } @incollection{WolffSeefeldtBaueretal.2014, author = {Wolff, Nino and Seefeldt, Patric and Bauer, Wolfgang and Fiebig, Christopher and Gerding, Patrick and Parow-Souchon, Kai and Pongs, Anna and Reiffenrath, Matti and Ziemann, Thomas}, title = {Alternative application of solar sail technology}, series = {Advances in solar sailing}, booktitle = {Advances in solar sailing}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-642-34906-5 (Print) ; 978-3-642-34907-2 (E-Book)}, doi = {10.1007/978-3-642-34907-2_23}, pages = {351 -- 365}, year = {2014}, abstract = {The development of Gossamer sail structures for solar sails contributes to a large field of future space applications like thin film solar generators, membrane antennas and drag sails. The focus of this paper is the development of a drag sail based on solar sail technology that could contribute to a reduction of space debris in low Earth orbits. The drag sail design and its connections to solar sail development, a first test on a sounding rocket, as well as the ongoing integration of the drag sail into a triple CubeSat is presented.}, language = {en} } @inproceedings{WolfWiese2013, author = {Wolf, Martin and Wiese, Ute}, title = {A comparative transformation model for process changes using serious games}, series = {2013 IEEE 2nd International Conference on Serious Games and Applications for Health (SeGAH): proceedings of a meeting held 2-3 May 2013, Algarve, Portugal}, booktitle = {2013 IEEE 2nd International Conference on Serious Games and Applications for Health (SeGAH): proceedings of a meeting held 2-3 May 2013, Algarve, Portugal}, publisher = {Institute of Electrical and Electronics Engineers (IEEE)}, address = {Piscataway, NJ}, organization = {International Conference on Serious Games and Applications for Health <2, 2013, Algarve>}, isbn = {978-1-4673-6164-4}, doi = {10.1109/SeGAH.2013.6665307}, pages = {64 -- 70}, year = {2013}, language = {en} } @article{WolfSimonSchlick1998, author = {Wolf, Martin and Simon, S. and Schlick, Christopher}, title = {Qualitative and Quantitative Analysis of Cooperation / Wolf, M. ; Simon, S. ; Schlick, C.}, series = {Proceedings : May 26 - 29, 1998, Cannes (France) = Actes : 26 - 29 mai 1998 / INRIA, Institut National de Recherche en Informatique et en Automatique, Unit{\´e} de recherche ... F. Darses ..., eds}, journal = {Proceedings : May 26 - 29, 1998, Cannes (France) = Actes : 26 - 29 mai 1998 / INRIA, Institut National de Recherche en Informatique et en Automatique, Unit{\´e} de recherche ... F. Darses ..., eds}, publisher = {-}, address = {Cannes}, pages = {1 -- 5}, year = {1998}, language = {en} } @article{WolfSchlickSpringer1997, author = {Wolf, Martin and Schlick, Christopher and Springer, J.}, title = {The use of implicit communication mechanisms in desktop-teleconferencing-systems}, series = {Proceedings of WWDU '97 Tokyo, Fifth International Scientific Conference on Work with Display Units : November 3 - 5, 1997, Tokyo}, journal = {Proceedings of WWDU '97 Tokyo, Fifth International Scientific Conference on Work with Display Units : November 3 - 5, 1997, Tokyo}, editor = {Miyamoto, Hiroyuki}, publisher = {-}, address = {Tokyo}, pages = {193 -- 194}, year = {1997}, language = {en} } @article{WolfLuczakSpringeretal.1997, author = {Wolf, Martin and Luczak, Holger and Springer, J. and Simon, S.}, title = {The role of metaphors in computer supported cooperative work}, series = {Proceedings of WWDU '97 Tokyo, Fifth International Scientific Conference on Work with Display Units : November 3 - 5, 1997, Tokyo /}, journal = {Proceedings of WWDU '97 Tokyo, Fifth International Scientific Conference on Work with Display Units : November 3 - 5, 1997, Tokyo /}, editor = {Miyamoto, Hiroyuki}, publisher = {-}, address = {Tokyo}, pages = {191 -- 192}, year = {1997}, language = {en} } @article{WolfLuczak1999, author = {Wolf, Martin and Luczak, Holger}, title = {Computer Supported Communication and Cooperation - Making Information Aware / Luczak, H. ; Wolf, M.}, series = {Human-computer interaction : proceedings of HCI International '99 (the 8th International Conference on Human-Computer Interaction), Munich, Germany, August 22 - 26, 1999}, journal = {Human-computer interaction : proceedings of HCI International '99 (the 8th International Conference on Human-Computer Interaction), Munich, Germany, August 22 - 26, 1999}, publisher = {Erlbaum}, address = {Mahwah, NJ}, pages = {298 -- 302}, year = {1999}, language = {en} } @inproceedings{WolfLenz2015, author = {Wolf, Martin and Lenz, Laura L.}, title = {The economic effectiveness of serious games in the healthcare environment : application and evaluation of the Comparative Transformation Model (CTM)}, series = {IEEE 3rd International Conference on Serious Games and Applications for Health : SeGAH 2014 ; Rio de Janeiro, Brazil, May 14 - 16}, booktitle = {IEEE 3rd International Conference on Serious Games and Applications for Health : SeGAH 2014 ; Rio de Janeiro, Brazil, May 14 - 16}, publisher = {IEEE [u.a.]}, address = {Piscataway, NJ}, isbn = {978-1-4799-4823-9}, doi = {10.1109/SeGAH.2014.7067089}, pages = {135 -- 142}, year = {2015}, language = {en} } @article{WolfFoltzSchlicketal.2000, author = {Wolf, Martin and Foltz, Christian and Schlick, Christopher and Luczak, Holger}, title = {Empirical Investigation of a workspace model for Chemical engineers / Wolf, Martin ; Foltz, Christian ; Schlick, Christopher ; Luczak, Holger}, series = {Proceedings of the Human Factors and Ergonomics Society Annual Meeting July 2000. 44 (2000), H. 6}, journal = {Proceedings of the Human Factors and Ergonomics Society Annual Meeting July 2000. 44 (2000), H. 6}, publisher = {-}, pages = {612 -- 615}, year = {2000}, language = {en} } @article{WolfFoltzSchlicketal.2002, author = {Wolf, Martin and Foltz, Christian and Schlick, Christopher and Luczak, Holger}, title = {Development and evaluation of a groupware system to support chemical design processes / Wolf, Martin ; Foltz, Christian ; Schlick, Christopher ; Luczak, Holger}, series = {International Journal of Human-Computer Interaction . 14 (2002), H. 2}, journal = {International Journal of Human-Computer Interaction . 14 (2002), H. 2}, publisher = {-}, isbn = {1044-7318}, pages = {181 -- 198}, year = {2002}, language = {en} } @article{WolfFoltzSchlicketal.1999, author = {Wolf, Martin and Foltz, Christian and Schlick, Christopher and Luczak, Holger}, title = {Groupware support for chemical process design / Wolf, M.; Foltz, C.; Schlick, C.; Luczak, H.}, series = {Human-computer interaction : proceedings of HCI International '99 (the 8th International Conference on Human-Computer Interaction), Munich, Germany, August 22 - 26, 1999}, journal = {Human-computer interaction : proceedings of HCI International '99 (the 8th International Conference on Human-Computer Interaction), Munich, Germany, August 22 - 26, 1999}, publisher = {Erlbaum}, address = {Mahwah, NJ}, pages = {343 -- 347}, year = {1999}, language = {en} } @article{WolfFoltzKillichetal.2001, author = {Wolf, Martin and Foltz, Christian and Killich, Stephan and Schmidt, Ludger}, title = {Task and Information Modeling for Cooperative Work / Foltz, Christian ; Killich, Stephan ; Wolf, Martin ; Schmidt, Ludger ; Luczak, Holger}, series = {Systems, social and internationalization design aspects of human-computer interaction / ed. by Michael J. Smith, Gavriel Salvendy Vol. 2}, journal = {Systems, social and internationalization design aspects of human-computer interaction / ed. by Michael J. Smith, Gavriel Salvendy Vol. 2}, publisher = {-}, isbn = {0-8058-3608-X}, pages = {172 -- 176}, year = {2001}, language = {en} } @book{WolfFoltzKillich2000, author = {Wolf, Martin and Foltz, Christian and Killich, S.}, title = {K3 User Guide}, publisher = {RWTH}, address = {Aachen}, pages = {1 -- 13}, year = {2000}, language = {en} } @article{Wolf2000, author = {Wolf, Martin}, title = {Groupware related task design}, series = {ACM SIGGROUP Bulletin. 21 (2000), H. 2}, journal = {ACM SIGGROUP Bulletin. 21 (2000), H. 2}, publisher = {-}, pages = {5 -- 8}, year = {2000}, language = {en} } @article{Wolf2000, author = {Wolf, Martin}, title = {Groupware related task design}, series = {ACM SIGGROUP Bulletin}, volume = {21}, journal = {ACM SIGGROUP Bulletin}, number = {2}, issn = {2372-7403}, doi = {10.1145/605660.605662}, pages = {5 -- 8}, year = {2000}, abstract = {his report summarizes the results of a workshop on Groupware related task design which took place at the International Conference on Supporting Group Work Group'99, Arizona, from 14 th to 17 th November 1999. The workshop was addressed to people from different viewpoints, backgrounds, and domains: - Researchers dealing with questions of task analysis and task modeling for Groupware application from an academic point of view. They may contribute modelbased design approaches or theoretically oriented work - Practitioners with experience in the design and everyday use of groupware systems. They might refer to the practical side of the topic: "real" tasks, "real" problems, "real" users, etc.}, language = {en} } @incollection{WolfKapelyukhScheeretal.2015, author = {Wolf, C. Roland and Kapelyukh, Yury and Scheer, Nico and Henderson, Colin J.}, title = {Application of Humanised and Other Transgenic Models to Predict Human Responses to Drugs}, editor = {Wilson, Alan G. E.}, publisher = {RSC Publ.}, address = {Cambridge}, isbn = {978-1-78262-778-4}, doi = {10.1039/9781782622376-00152}, pages = {152 -- 176}, year = {2015}, abstract = {The use of transgenic animal models has transformed our knowledge of complex biochemical pathways in vivo. It has allowed disease processes to be modelled and used in the development of new disease prevention and treatment strategies. They can also be used to define cell- and tissue-specific pathways of gene regulation. A further major application is in the area of preclinical development where such models can be used to define pathways of chemical toxicity, and the pathways that regulate drug disposition. One major application of this approach is the humanisation of mice for the proteins that control drug metabolism and disposition. Such models can have numerous applications in the development of drugs and in their more sophisticated use in the clinic.}, language = {en} } @article{WittmannUlamecFeuerbacheretal.1997, author = {Wittmann, Klaus and Ulamec, S. and Feuerbacher, B. and Rosenbauer, H. (u.a.)}, title = {Rosetta Lander - In Situ Investigation of a Cometary Nucleus}, series = {Lunar and Planetary Science. 28 (1997)}, journal = {Lunar and Planetary Science. 28 (1997)}, isbn = {0270-9511}, pages = {1461 -- 1462}, year = {1997}, language = {en} } @article{WittmannUlamecFeuerbacheretal.1995, author = {Wittmann, Klaus and Ulamec, S. and Feuerbacher, B. and Rosenbauer, H.}, title = {Technical Challenge, Scientific Thrill: A Long Term Lander on an Active Comet}, series = {Lunar and Planetary Science. 26 (1995)}, journal = {Lunar and Planetary Science. 26 (1995)}, isbn = {0270-9511}, pages = {1431 -- 1432}, year = {1995}, language = {en} } @article{WittmannUlamecRichter1999, author = {Wittmann, Klaus and Ulamec, S and Richter, L}, title = {Lander Systems for Planetary Missions}, series = {Laboratory astrophysics and space research / ed. by P. Ehrenfreund}, journal = {Laboratory astrophysics and space research / ed. by P. Ehrenfreund}, publisher = {Kluwer}, address = {Dordrecht [u.a.]}, isbn = {0-7923-5338-2}, pages = {597 -- 621}, year = {1999}, language = {en} } @article{WittmannSchmidtPadekenetal.1988, author = {Wittmann, Klaus and Schmidt, H. P. and Padeken, D. and Hildmann, B.}, title = {The Microgravity User Support Centre (MUSC)}, series = {ESA SP. 277 (1988)}, journal = {ESA SP. 277 (1988)}, isbn = {0379-6566}, pages = {525}, year = {1988}, language = {en} } @article{WittmannSchmidtFeuerbacher1988, author = {Wittmann, Klaus and Schmidt, H. P. and Feuerbacher, B.}, title = {Microgravity research and user support in the Space Station era: The Microgravity User Support Centre}, series = {Acta Astronautica. 17 (1988), H. 11-12}, journal = {Acta Astronautica. 17 (1988), H. 11-12}, isbn = {0094-5765}, pages = {1161 -- 1168}, year = {1988}, language = {en} } @article{WittmannPadeken1993, author = {Wittmann, Klaus and Padeken, D.}, title = {The User Center for Microgravity MUSC - Support for space experiments}, series = {DLR-Nachrichten. 70 (1993)}, journal = {DLR-Nachrichten. 70 (1993)}, isbn = {0937-0420}, pages = {19 -- 24}, year = {1993}, language = {en} } @article{WittmannKellWinkleretal.1998, author = {Wittmann, Klaus and Kell, G. and Winkler, F. and G{\"u}nther, M. (u.a.)}, title = {High resolution temperature measurement technique for materials sciences experiments in space}, series = {Acta Astronautica. 43 (1998), H. 7-8}, journal = {Acta Astronautica. 43 (1998), H. 7-8}, isbn = {0094-5765}, pages = {385 -- 395}, year = {1998}, language = {en} } @article{WittmannKehrWillnecker2000, author = {Wittmann, Klaus and Kehr, J. and Willnecker, R.}, title = {Decentralized Payload Operations Concept for Columbus}, year = {2000}, language = {en} } @article{WittmannGillessenOttoetal.1996, author = {Wittmann, Klaus and Gillessen, F. and Otto, G. and R{\"o}stel, R.}, title = {Undercooling and solidification of metallic melts suspended in a non-nucleating matrix: Experiment NUCAL of the German Spacelab Mission D-2}, series = {Acta Astronautica. 38 (1996), H. 1}, journal = {Acta Astronautica. 38 (1996), H. 1}, isbn = {0094-5765}, pages = {63 -- 68}, year = {1996}, language = {en} } @article{WittmannFortezza1992, author = {Wittmann, Klaus and Fortezza, R.}, title = {Telescience opportunities in the precursor flights}, series = {Space Technology - Industrial and Commercial Applications. 13 (1992), H. 2}, journal = {Space Technology - Industrial and Commercial Applications. 13 (1992), H. 2}, isbn = {0892-9270}, pages = {221 -- 226}, year = {1992}, language = {en} } @article{WittmannFeuerbacherUlamecetal.1999, author = {Wittmann, Klaus and Feuerbacher, B. and Ulamec, S. and Rosenbauer, H. (u.a.)}, title = {Rosetta Lander - In Situ Characterisation of a Comet Nucleus}, series = {Acta Astronautica. 45 (1999), H. 4-9}, journal = {Acta Astronautica. 45 (1999), H. 4-9}, isbn = {0094-5765}, pages = {389 -- 395}, year = {1999}, language = {en} } @article{WittmannBibringRosenbaueretal.2007, author = {Wittmann, Klaus and Bibring, J.-P. and Rosenbauer, H. and Boehnhardt, H.}, title = {The Rosetta Lander ("Philae") Investigations / Bibring, J.-P. ; Rosenbauer, H. ; Boehnhardt, H. ; [...] Wittmann, K.}, series = {Space Science Reviews. 128 (2007), H. 1-4}, journal = {Space Science Reviews. 128 (2007), H. 1-4}, isbn = {0038-6308}, pages = {205 -- 220}, year = {2007}, language = {en} } @article{WittmannBewersdorffGoerleretal.1993, author = {Wittmann, Klaus and Bewersdorff, A. and G{\"o}rler, G.P. and Otto, G.}, title = {Solidification of silver-germanium alloys in an amorphous matrix aboard the space station Mir}, series = {Acta Astronautica. 29 (1993), H. 7}, journal = {Acta Astronautica. 29 (1993), H. 7}, isbn = {0094-5765}, pages = {547 -- 552}, year = {1993}, language = {en} } @article{Wittmann1993, author = {Wittmann, Klaus}, title = {The microgravity User Support Centre}, series = {Space Technology - Industrial and Commercial Applications. 13 (1993), H. 2}, journal = {Space Technology - Industrial and Commercial Applications. 13 (1993), H. 2}, isbn = {0892-9270}, pages = {121 -- 124}, year = {1993}, language = {en} } @article{Wittmann2000, author = {Wittmann, Klaus}, title = {Overview of Space Operations at DLR}, year = {2000}, language = {en} } @inproceedings{WittigRuettersBragard2024, author = {Wittig, M. and R{\"u}tters, Ren{\´e} and Bragard, Michael}, title = {Application of RL in control systems using the example of a rotatory inverted pendulum}, series = {Tagungsband AALE 2024 : Fit f{\"u}r die Zukunft: praktische L{\"o}sungen f{\"u}r die industrielle Automation}, booktitle = {Tagungsband AALE 2024 : Fit f{\"u}r die Zukunft: praktische L{\"o}sungen f{\"u}r die industrielle Automation}, editor = {Reiff-Stephan, J{\"o}rg and J{\"a}kel, Jens and Schwarz, Andr{\´e}}, publisher = {le-tex publishing services GmbH}, address = {Leipzig}, isbn = {978-3-910103-02-3}, doi = {10.33968/2024.53}, pages = {241 -- 248}, year = {2024}, abstract = {In this paper, the use of reinforcement learning (RL) in control systems is investigated using a rotatory inverted pendulum as an example. The control behavior of an RL controller is compared to that of traditional LQR and MPC controllers. This is done by evaluating their behavior under optimal conditions, their disturbance behavior, their robustness and their development process. All the investigated controllers are developed using MATLAB and the Simulink simulation environment and later deployed to a real pendulum model powered by a Raspberry Pi. The RL algorithm used is Proximal Policy Optimization (PPO). The LQR controller exhibits an easy development process, an average to good control behavior and average to good robustness. A linear MPC controller could show excellent results under optimal operating conditions. However, when subjected to disturbances or deviations from the equilibrium point, it showed poor performance and sometimes instable behavior. Employing a nonlinear MPC Controller in real time was not possible due to the high computational effort involved. The RL controller exhibits by far the most versatile and robust control behavior. When operated in the simulation environment, it achieved a high control accuracy. When employed in the real system, however, it only shows average accuracy and a significantly greater performance loss compared to the simulation than the traditional controllers. With MATLAB, it is not yet possible to directly post-train the RL controller on the Raspberry Pi, which is an obstacle to the practical application of RL in a prototyping or teaching setting. Nevertheless, RL in general proves to be a flexible and powerful control method, which is well suited for complex or nonlinear systems where traditional controllers struggle.}, language = {en} } @article{WissenbachSixBongaertsetal.1995, author = {Wissenbach, U. and Six, S. and Bongaerts, Johannes and Ternes, D. and Steinwachs, S. and Unden, G.}, title = {A third periplasmic transport system for l-arginine in Escherichia coli: molecular characterization of the artPIQMJ genes, arginine binding and transport}, series = {Molecular microbiology}, volume = {Vol. 17}, journal = {Molecular microbiology}, number = {Iss. 4}, issn = {1365-2958 (E-Journal); 0950-382x (Print)}, pages = {675 -- 686}, year = {1995}, language = {en} } @article{WissenBogdanskiScheeretal.2005, author = {Wissen, M. and Bogdanski, N. and Scheer, H.-C. and Bitz, Andreas and Ahrens, G. and Gruetzner, G.}, title = {Implication of the light polarisation for UV curing of pre-patterned resists}, series = {Microelectronic Engineering}, volume = {78-79}, journal = {Microelectronic Engineering}, issn = {0167-9317}, doi = {10.1016/j.mee.2004.12.099}, pages = {659 -- 664}, year = {2005}, language = {en} } @article{WincklerKruegerSchnitzleretal.2014, author = {Winckler, Silvia and Krueger, Rolf and Schnitzler, Thomas and Zang, Werner and Fischer, Rainer and Biselli, Manfred}, title = {A sensitive monitoring system for mammalian cell cultivation processes: a PAT approach}, series = {Bioprocess and biosystems engineering}, volume = {37}, journal = {Bioprocess and biosystems engineering}, number = {5}, publisher = {Springer}, address = {Berlin, Heidelberg}, issn = {1615-7591 (Print) 1615-7605 (Online)}, doi = {10.1007/s00449-013-1062-8}, pages = {901 -- 912}, year = {2014}, abstract = {Biopharmaceuticals such as antibodies are produced in cultivated mammalian cells, which must be monitored to comply with good manufacturing practice. We, therefore, developed a fully automated system comprising a specific exhaust gas analyzer, inline analytics and a corresponding algorithm to precisely determine the oxygen uptake rate, carbon dioxide evolution rate, carbon dioxide transfer rate, transfer quotient and respiratory quotient without interrupting the ongoing cultivation, in order to assess its reproducibility. The system was verified using chemical simulation experiments and was able to measure the respiratory activity of hybridoma cells and DG44 cells (derived from Chinese hamster ovary cells) with satisfactory results at a minimum viable cell density of ~2.0 × 10⁵ cells ml⁻¹. The system was suitable for both batch and fed-batch cultivations in bubble-aerated and membrane-aerated reactors, with and without the control of pH and dissolved oxygen.}, language = {en} } @article{WilsonBlomeLaFave1996, author = {Wilson, Thomas L and Blome, Hans-Joachim and LaFave, Norman}, title = {Astrophysical Cosmology Using a Lunar Ligo}, series = {Engineering, construction, and operations in space V : proceedings of the Fifth International Conference on Space '96, Albuquerque, New Mexico, June 1-6, 1996 / sponsored by Aerospace Division of the American Society of Civil Engineers ... [et al.]; edite}, journal = {Engineering, construction, and operations in space V : proceedings of the Fifth International Conference on Space '96, Albuquerque, New Mexico, June 1-6, 1996 / sponsored by Aerospace Division of the American Society of Civil Engineers ... [et al.]; edite}, publisher = {The Society}, address = {New York}, isbn = {0-7844-0177-2}, pages = {861 -- 863}, year = {1996}, language = {en} } @article{WilsonBlome2009, author = {Wilson, T. L. and Blome, Hans-Joachim}, title = {The Pioneer anomaly and a rotating G{\"o}del universe}, series = {Advances in Space Research}, volume = {44}, journal = {Advances in Space Research}, number = {11}, isbn = {0273-1177}, pages = {1345 -- 1353}, year = {2009}, language = {en} } @article{WilsonWilsonScheeretal.2017, author = {Wilson, Ian D. and Wilson, Claire E. and Scheer, Nico and Dickie, A.P. and Schreiter, K. and Wilson, E. M. and Riley, R. J. and Wehr, R. and Bial, J.}, title = {The Pharmacokinetics and Metabolism of Lumiracoxib in Chimeric Humanized and Murinized FRG Mice}, series = {Biochemical pharmacology}, volume = {Volume 135}, journal = {Biochemical pharmacology}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-2968}, doi = {10.1016/j.bcp.2017.03.015}, pages = {139 -- 150}, year = {2017}, language = {en} } @article{WilsonDickieSchreiteretal.2018, author = {Wilson, C. E. and Dickie, A. P. and Schreiter, K. and Wehr, R. and Wilson, E. M. and Bial, J. and Scheer, Nico and Wilson, I. D. and Riley, R. J.}, title = {The pharmacokinetics and metabolism of diclofenac in chimeric humanized and murinized FRG mice}, series = {Archives of Toxicology}, volume = {92}, journal = {Archives of Toxicology}, number = {6}, publisher = {Springer}, issn = {1432-0738}, doi = {10.1007/s00204-018-2212-1}, pages = {1953 -- 1967}, year = {2018}, abstract = {The pharmacokinetics of diclofenac were investigated following single oral doses of 10 mg/kg to chimeric liver humanized and murinized FRG and C57BL/6 mice. In addition, the metabolism and excretion were investigated in chimeric liver humanized and murinized FRG mice. Diclofenac reached maximum blood concentrations of 2.43 ± 0.9 µg/mL (n = 3) at 0.25 h post-dose with an AUCinf of 3.67 µg h/mL and an effective half-life of 0.86 h (n = 2). In the murinized animals, maximum blood concentrations were determined as 3.86 ± 2.31 µg/mL at 0.25 h post-dose with an AUCinf of 4.94 ± 2.93 µg h/mL and a half-life of 0.52 ± 0.03 h (n = 3). In C57BL/6J mice, mean peak blood concentrations of 2.31 ± 0.53 µg/mL were seen 0.25 h post-dose with a mean AUCinf of 2.10 ± 0.49 µg h/mL and a half-life of 0.51 ± 0.49 h (n = 3). Analysis of blood indicated only trace quantities of drug-related material in chimeric humanized and murinized FRG mice. Metabolic profiling of urine, bile and faecal extracts revealed a complex pattern of metabolites for both humanized and murinized animals with, in addition to unchanged parent drug, a variety of hydroxylated and conjugated metabolites detected. The profiles in humanized mice were different to those of both murinized and wild-type animals, e.g., a higher proportion of the dose was detected in the form of acyl glucuronide metabolites and much reduced amounts as taurine conjugates. Comparison of the metabolic profiles obtained from the present study with previously published data from C57BL/6J mice and humans revealed a greater, though not complete, match between chimeric humanized mice and humans, such that the liver humanized FRG model may represent a model for assessing the biotransformation of such compounds in humans.}, language = {en} } @article{WilmingBegemannKuhneetal.2013, author = {Wilming, Anja and Begemann, Jens and Kuhne, Stefan and Regestein, Lars and Bongaerts, Johannes and Evers, Stefan and Maurer, Karl-Heinz and B{\"u}chs, Jochen}, title = {Metabolic studies of γ-polyglutamic acid production in Bacillus licheniformis by small-scale continuous cultivations}, series = {Biochemical engineering journal}, volume = {Vol. 73}, journal = {Biochemical engineering journal}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-295X (E-Journal); 1369-703X (Print)}, pages = {29 -- 37}, year = {2013}, language = {en} } @incollection{Wilke2016, author = {Wilke, Thomas}, title = {Planning Process of the Di Castellamonte's Chapel of the Holy Shroud}, series = {Carlo e Amedeo di Castellamonte : 1571-1683, ingegneri e architetti per i duchi di Savoia}, booktitle = {Carlo e Amedeo di Castellamonte : 1571-1683, ingegneri e architetti per i duchi di Savoia}, editor = {Merlotti, Andrea}, publisher = {Campisano editore}, address = {Rom}, isbn = {978-88-98229-57-4}, pages = {141 -- 152}, year = {2016}, language = {en} } @article{Wilke2017, author = {Wilke, Thomas}, title = {Newly found plans for the chapel of the Holy Shroud}, series = {Studi Piemontesi}, volume = {XLVI}, journal = {Studi Piemontesi}, number = {1}, issn = {0392-7261}, pages = {75 -- 85}, year = {2017}, language = {en} } @article{WildSchrezenmeierCzupallaetal.2020, author = {Wild, Dominik and Schrezenmeier, Johannes and Czupalla, Markus and F{\"o}rstner, Markus}, title = {Thermal Characterization of additive manufactured Integral Structures for Phase Change Applications}, series = {2020 International Conference on Environmental Systems}, journal = {2020 International Conference on Environmental Systems}, publisher = {Texas Tech University}, year = {2020}, abstract = {"Infused Thermal Solutions" (ITS) introduces a method for passive thermal control to stabilize structural components thermally without active heating and cooling systems, by using phase change material (PCM) in combination with lattice - both embedded into an additive manufactured integral structure. The technology is currently under development. This paper presents the results of the thermal property measurements performed on additive manufactured ITS breadboards. Within the breadboard campaigns key characteristics of the additive manufactured specimens were derived: Mechanical parameters: specimen impermeability, minimum wall thickness, lattice structure, subsequent heat treatment. Thermal properties: thermo-optical surface properties of the additive manufactured raw material, thermal conductivity and specific heat capacity measurements. As a conclusion the paper introduces an overview of potential ITS hardware applications, expected to increase the thermal performance.}, language = {en} } @article{WiesenTippkoetterMuffleretal.2015, author = {Wiesen, Sebastian and Tippk{\"o}tter, Nils and Muffler, Kai and Suck, Kirstin and Sohling, Ulrich and Ruf, Friedrich and Ulber, Roland}, title = {Adsorption of fatty acids to layered double hydroxides in aqueous systems}, series = {Adsorption}, volume = {21}, journal = {Adsorption}, number = {6-7}, publisher = {Springer}, address = {Berlin}, pages = {459 -- 466}, year = {2015}, abstract = {Due to their anion exchange characteristics, layered double hydroxides (LDHs) are suitable for the detoxification of aqueous, fatty acid containing fermentation substrates. The aim of this study is to examine the adsorption mechanism, using crude glycerol from plant oil esterification as a model system. Changes in the intercalation structure in relation to the amount of fatty acids adsorbed are monitored by X-ray diffraction and infra-red spectroscopy. Additionally, calcination of LDH is investigated in order to increase the binding capacity for fatty acids. Our data propose that, at ambient temperature, fatty acids can be bound to the hydrotalcite by adsorption or in addition by intercalation, depending on fatty acid concentration. The adsorption of fatty acids from crude glycerol shows a BET-like behavior. Above a fatty acid concentration of 3.5 g L-1, intercalation of fatty acids can be shown by the appearance of an increased interlayer spacing. This observation suggests a two phase adsorption process. Calcination of LDHs allows increasing the binding capacity for fatty acids by more than six times, mainly by reduction of structural CO32-.}, language = {en} } @inproceedings{WiesenEngemannLimpertetal.2018, author = {Wiesen, Patrick and Engemann, Heiko and Limpert, Nicolas and Kallweit, Stephan}, title = {Learning by Doing - Mobile Robotics in the FH Aachen ROS Summer School}, series = {European Robotics Forum 2018, TRROS18 Workshop}, booktitle = {European Robotics Forum 2018, TRROS18 Workshop}, pages = {47 -- 58}, year = {2018}, language = {en} } @inproceedings{WiegnerVolkerMainzetal.2022, author = {Wiegner, Jonas and Volker, Hanno and Mainz, Fabian and Backes, Andreas and L{\"o}ken, Michael and H{\"u}ning, Felix}, title = {Wiegand-effect-powered wireless IoT sensor node}, series = {Sensoren und Messsysteme 2022}, booktitle = {Sensoren und Messsysteme 2022}, publisher = {VDE Verlag GmbH}, address = {Berlin}, isbn = {978-3-8007-5835-7}, pages = {255 -- 260}, year = {2022}, abstract = {In this article we describe an Internet-of-Things sensing device with a wireless interface which is powered by the oftenoverlooked harvesting method of the Wiegand effect. The sensor can determine position, temperature or other resistively measurable quantities and can transmit the data via an ultra-low power ultra-wideband (UWB) data transmitter. With this approach we can energy-self-sufficiently acquire, process, and wirelessly transmit data in a pulsed operation. A proof-of-concept system was built up to prove the feasibility of the approach. The energy consumption of the system is analyzed and traced back in detail to the individual components, compared to the generated energy and processed to identify further optimization options. Based on the proof-of-concept, an application demonstrator was developed. Finally, we point out possible use cases.}, language = {en} } @misc{WiegnerVolkerMainzetal.2022, author = {Wiegner, J. and Volker, H. and Mainz, F. and Backes, A. and L{\"o}ken, M. and H{\"u}ning, Felix}, title = {Wiegand-Effect-Powered Wireless IT Sensor Node}, year = {2022}, abstract = {With the growing interest in small distributed sensors for the "Internet of Things", more attention is being paid to energy harvesting techologies. Reducing or eliminating the need for external power sources or batteries make devices more self-sufficient, more reliable, and reduces maintenance requirements. The Wiegand effect is a proven technology for harvesting small amounts of electrical power from mechanical motion.}, language = {en} } @article{WiegandVoigtAlbrechtetal.2013, author = {Wiegand, Sandra and Voigt, Birgit and Albrecht, Dirk and Bongaerts, Johannes and Evers, Stefan and Hecker, Michael and Daniel, Rolf and Liesegang, Heiko}, title = {Fermentation stage-dependent adaptations of Bacillus licheniformis during enzyme production}, series = {Microbial Cell Factories}, volume = {12}, journal = {Microbial Cell Factories}, publisher = {Biomed Central}, address = {London}, issn = {1475-2859}, doi = {10.1186/1475-2859-12-120}, pages = {120}, year = {2013}, language = {en} } @article{WiegandDietrichHerteletal.2013, author = {Wiegand, Sandra and Dietrich, Sascha and Hertel, Robert and Bongaerts, Johannes and Evers, Stefan and Volland, Sonja and Daniel, Rolf and Liesegang, Heiko}, title = {RNA-Seq of Bacillus licheniformis: active regulatory RNA features expressed within a productive fermentation}, series = {BMC genomics}, volume = {Vol. 14}, journal = {BMC genomics}, publisher = {BioMed Central}, address = {London}, issn = {1471-2164}, pages = {667}, year = {2013}, language = {en} } @article{WhiteheadOehlschlaegerAlmajhdietal.2014, author = {Whitehead, Mark and {\"O}hlschl{\"a}ger, Peter and Almajhdi, Fahad N. and Alloza, Leonor and Marz{\´a}bal, Pablo and Meyers, Ann E. and Hitzeroth, Inga I. and Rybicki, Edward P.}, title = {Human papillomavirus (HPV) type 16 E7 protein bodies cause tumour regression in mice}, series = {BMC cancer}, journal = {BMC cancer}, number = {14:367}, publisher = {BioMed Central}, address = {London}, issn = {1471-2407}, doi = {10.1186/1471-2407-14-367}, pages = {1 -- 15}, year = {2014}, language = {en} } @inproceedings{WetterKern2014, author = {Wetter, Martin and Kern, Alexander}, title = {Number of lightning strikes to tall structures - comparison of calculations and measurements using a modern lightning monitoring system}, series = {2014 International Conference on Lightning Protection (ICLP), Shanghai, China}, booktitle = {2014 International Conference on Lightning Protection (ICLP), Shanghai, China}, organization = {International Conference on Lightning Protection <2014, Shanghai>}, pages = {1 -- 7}, year = {2014}, language = {en} } @article{WertIkenSchoeningetal.2021, author = {Wert, Stefan and Iken, Heiko and Sch{\"o}ning, Michael Josef and Matysik, Frank-Michael}, title = {Development of a temperature-pulse enhanced electrochemical glucose biosensor and characterization of its stability via scanning electrochemical microscopy}, series = {Electroanalysis}, journal = {Electroanalysis}, number = {Early View}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1521-4109}, doi = {10.1002/elan.202100089}, year = {2021}, abstract = {Glucose oxidase (GOx) is an enzyme frequently used in glucose biosensors. As increased temperatures can enhance the performance of electrochemical sensors, we investigated the impact of temperature pulses on GOx that was drop-coated on flattened Pt microwires. The wires were heated by an alternating current. The sensitivity towards glucose and the temperature stability of GOx was investigated by amperometry. An up to 22-fold increase of sensitivity was observed. Spatially resolved enzyme activity changes were investigated via scanning electrochemical microscopy. The application of short (<100 ms) heat pulses was associated with less thermal inactivation of the immobilized GOx than long-term heating.}, language = {en} } @inproceedings{WernerYoshinobuMiyamotoetal.2014, author = {Werner, Frederik and Yoshinobu, T. and Miyamoto, K. and Sch{\"o}ning, Michael Josef and Wagner, Torsten}, title = {Semiconductor-based sensors for imaging of chemical processes}, series = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)}, booktitle = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)}, publisher = {VDE-Verl.}, address = {D{\"u}sseldorf}, organization = {VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik}, isbn = {978-3-8007-3622-5}, pages = {1 -- 5}, year = {2014}, language = {en} } @article{WernerWagnerYoshinobuetal.2013, author = {Werner, Frederik and Wagner, Torsten and Yoshinobu, Tatsuo and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Frequency behaviour of light-addressable potentiometric sensors}, series = {Physica Status Solidi (A)}, volume = {210}, journal = {Physica Status Solidi (A)}, number = {5}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1521-396X ; 0031-8965}, doi = {10.1002/pssa.201200929}, pages = {884 -- 891}, year = {2013}, abstract = {Light-addressable potentiometric sensors (LAPS) are semiconductor-based potentiometric sensors, with the advantage to detect the concentration of a chemical species in a liquid solution above the sensor surface in a spatially resolved manner. The addressing is achieved by a modulated and focused light source illuminating the semiconductor and generating a concentration-depending photocurrent. This work introduces a LAPS set-up that is able to monitor the electrical impedance in addition to the photocurrent. The impedance spectra of a LAPS structure, with and without illumination, as well as the frequency behaviour of the LAPS measurement are investigated. The measurements are supported by electrical equivalent circuits to explain the impedance and the LAPS-frequency behaviour. The work investigates the influence of different parameters on the frequency behaviour of the LAPS. Furthermore, the phase shift of the photocurrent, the influence of the surface potential as well as the changes of the sensor impedance will be discussed.}, language = {en} } @article{WernerWagnerMiyamotoetal.2012, author = {Werner, Frederik and Wagner, Torsten and Miyamoto, Ko-ichiro and Yoshinobu, Tatsuo and Sch{\"o}ning, Michael Josef}, title = {High speed and high resolution chemical imaging based on a new type of OLED-LAPS set-up}, series = {Sensors and Actuators B: Chemical}, volume = {175}, journal = {Sensors and Actuators B: Chemical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2011.12.102}, pages = {118 -- 122}, year = {2012}, abstract = {Light-addressable potentiometric sensors (LAPS) are field-effect-based sensors. A modulated light source is used to define the particular measurement spot to perform spatially resolved measurements of chemical species and to generate chemical images. In this work, an organic-LED (OLED) display has been chosen as a light source. This allows high measurement resolution and miniaturisation of the system. A new developed driving method for the OLED display optimised for LAPS-based measurements is demonstrated. The new method enables to define modulation frequencies between 1 kHz and 16 kHz and hence, reduces the measurement time of a chemical image by a factor of 40 compared to the traditional addressing of an OLED display.}, language = {en} } @article{WernerWagnerMiyamotoetal.2011, author = {Werner, Frederik and Wagner, Torsten and Miyamoto, Ko-ichiro and Yoshinobu, Tatsuo and Sch{\"o}ning, Michael Josef}, title = {High speed and high resolution chemical imaging based on a new type of OLED-LAPS set-up}, series = {Procedia Engineering. 25 (2011)}, journal = {Procedia Engineering. 25 (2011)}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {1877-7058}, pages = {346 -- 349}, year = {2011}, language = {en} } @article{WernerTakenagaTakietal.2013, author = {Werner, Frederik and Takenaga, Shoko and Taki, Hidenori and Sawada, Kazuaki and Sch{\"o}ning, Michael Josef}, title = {Comparison of label-free ACh-imaging sensors based on CCD and LAPS}, series = {Sensors and Actuators B: Chemical (2012)}, volume = {177}, journal = {Sensors and Actuators B: Chemical (2012)}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {0925-4005}, pages = {745 -- 752}, year = {2013}, abstract = {Semiconductor-based chemical imaging sensors, like the light-addressable potentiometric sensor (LAPS) or the pH-imaging sensor based on a charge-coupled device (CCD), are becoming a powerful tool for label-free imaging of biological phenomena. We have proposed a polyion-based enzymatic membrane to develop an acetylcholine (ACh) imaging sensor for neural cell-activity observations. In this study, a CCD-type ACh-imaging sensor and a LAPS-type ACh-imaging sensor were fabricated and the prospect of both sensors was clarified by making a comparison of their basic characteristics.}, language = {en} } @article{WernerSchusserSpalthahnetal.2011, author = {Werner, Frederik and Schusser, Sebastian and Spalthahn, Heiko and Wagner, Torsten and Yoshinobu, Tatsuo and Sch{\"o}ning, Michael Josef}, title = {Field-programmable gate array based controller for multi spot light-addressable potentiometric sensors with integrated signal correction mode}, series = {Electrochimica Acta}, volume = {56}, journal = {Electrochimica Acta}, number = {26}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0013-4686}, doi = {10.1016/j.electacta.2011.03.012}, pages = {9656 -- 9660}, year = {2011}, abstract = {A light-addressable potentiometric sensor (LAPS) can measure the concentration of one or several analytes at the sensor surface simultaneously in a spatially resolved manner. A modulated light pointer stimulates the semiconductor structure at the area of interest and a responding photocurrent can be read out. By simultaneous stimulation of several areas with light pointers of different modulation frequencies, the read out can be performed at the same time. With the new proposed controller electronic based on a field-programmable gate array (FPGA), it is possible to control the modulation frequencies, phase shifts, and light brightness of multiple light pointers independently and simultaneously. Thus, it is possible to investigate the frequency response of the sensor, and to examine the analyte concentration by the determination of the surface potential with the help of current/voltage curves and phase/voltage curves. Additionally, the ability to individually change the light intensities of each light pointer is used to perform signal correction.}, language = {en} } @article{WernerMiyamotoWagneretal.2017, author = {Werner, Frederik and Miyamoto, Ko-ichiro and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo}, title = {Lateral resolution enhancement of pulse-driven light-addressable potentiometric sensor}, series = {Sensor and Actuators B: Chemical}, volume = {248}, journal = {Sensor and Actuators B: Chemical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2017.02.057}, pages = {961 -- 965}, year = {2017}, abstract = {To study chemical and biological processes, spatially resolved determination of the concentrations of one or more analyte species is of distinct interest. With a light-addressable potentiometric sensor (LAPS), chemical images can be created, which visualize the concentration distribution above the sensor plate. One important challenge is to achieve a good lateral resolution in order to detect events that take place in a small and limited region. LAPS utilizes a focused light spot to address the measurement region. By moving this light spot along the semiconductor sensor plate, the concentration distribution can be observed. In this study, we show that utilizing a pulse as light excitation instead of a traditionally used continuously modulated light excitation, the lateral resolution can be improved by a factor of 6 or more.}, language = {en} } @article{WernerKrumbeSchumacheretal.2011, author = {Werner, Frederik and Krumbe, Christoph and Schumacher, Katharina and Groebel, Simone and Spelthahn, Heiko and Stellberg, Michael and Wagner, Torsten and Yoshinobu, Tatsuo and Selmer, Thorsten and Keusgen, Michael and Baumann, Marcus and Sch{\"o}ning, Michael Josef}, title = {Determination of the extracellular acidification of Escherichia coli by a light-addressable potentiometric sensor}, series = {Physica status solidi (a) : applications and material science. 208 (2011), H. 6}, journal = {Physica status solidi (a) : applications and material science. 208 (2011), H. 6}, publisher = {Wiley}, address = {Weinheim}, isbn = {1862-6319}, pages = {1340 -- 1344}, year = {2011}, language = {en} } @article{WernerGroebelKrumbeetal.2012, author = {Werner, Frederik and Groebel, Simone and Krumbe, Christoph and Wagner, Torsten and Selmer, Thorsten and Yoshinobu, Tatsuo and Baumann, Marcus and Sch{\"o}ning, Michael Josef}, title = {Nutrient concentration-sensitive microorganism-based biosensor}, series = {Physica Status Solidi (a)}, volume = {209}, journal = {Physica Status Solidi (a)}, number = {5}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201100801}, pages = {900 -- 904}, year = {2012}, language = {en} } @phdthesis{Werner2014, author = {Werner, Frederik}, title = {Development of light-addressable potentiometric sensor systems and their applications in biotechnological environments}, pages = {XI, 149 S.}, year = {2014}, language = {en} } @article{WerkhausenWillwacherAlbracht2021, author = {Werkhausen, Amelie and Willwacher, Steffen and Albracht, Kirsten}, title = {Medial gastrocnemius muscle fascicles shorten throughout stance during sprint acceleration}, series = {Scandinavian Journal of Medicine \& Science in Sports}, volume = {31}, journal = {Scandinavian Journal of Medicine \& Science in Sports}, number = {7}, publisher = {Wiley-Blackwell}, address = {Oxford}, issn = {0905-7188 (Druckausgabe)}, doi = {10.1111/sms.13956}, pages = {1471 -- 1480}, year = {2021}, abstract = {The compliant nature of distal limb muscle-tendon units is traditionally considered suboptimal in explosive movements when positive joint work is required. However, during accelerative running, ankle joint net mechanical work is positive. Therefore, this study aims to investigate how plantar flexor muscle-tendon behavior is modulated during fast accelerations. Eleven female sprinters performed maximum sprint accelerations from starting blocks, while gastrocnemius muscle fascicle lengths were estimated using ultrasonography. We combined motion analysis and ground reaction force measurements to assess lower limb joint kinematics and kinetics, and to estimate gastrocnemius muscle-tendon unit length during the first two acceleration steps. Outcome variables were resampled to the stance phase and averaged across three to five trials. Relevant scalars were extracted and analyzed using one-sample and two-sample t-tests, and vector trajectories were compared using statistical parametric mapping. We found that an uncoupling of muscle fascicle behavior from muscle-tendon unit behavior is effectively used to produce net positive mechanical work at the joint during maximum sprint acceleration. Muscle fascicles shortened throughout the first and second steps, while shortening occurred earlier during the first step, where negative joint work was lower compared with the second step. Elastic strain energy may be stored during dorsiflexion after touchdown since fascicles did not lengthen at the same time to dissipate energy. Thus, net positive work generation is accommodated by the reuse of elastic strain energy along with positive gastrocnemius fascicle work. Our results show a mechanism of how muscles with high in-series compliance can contribute to net positive joint work.}, language = {en} } @article{WerkhausenCroninAlbrachtetal.2019, author = {Werkhausen, Amelie and Cronin, Neil J. and Albracht, Kirsten and Paulsen, G{\o}ran and Larsen, Askild V. and Bojsen-M{\o}ller, Jens and Seynnes, Olivier R.}, title = {Training-induced increase in Achilles tendon stiffness affects tendon strain pattern during running}, series = {PeerJ}, journal = {PeerJ}, publisher = {Peer}, address = {London}, issn = {21678359}, doi = {10.7717/peerj.6764}, pages = {18 Seiten}, year = {2019}, abstract = {Background During the stance phase of running, the elasticity of the Achilles tendon enables the utilisation of elastic energy and allows beneficial contractile conditions for the triceps surae muscles. However, the effect of changes in tendon mechanical properties induced by chronic loading is still poorly understood. We tested the hypothesis that a training-induced increase in Achilles tendon stiffness would result in reduced tendon strain during the stance phase of running, which would reduce fascicle strains in the triceps surae muscles, particularly in the mono-articular soleus. Methods Eleven subjects were assigned to a training group performing isometric singleleg plantarflexion contractions three times per week for ten weeks, and another ten subjects formed a control group. Before and after the training period, Achilles tendon stiffness was estimated, and muscle-tendon mechanics were assessed during running at preferred speed using ultrasonography, kinematics and kinetics. Results Achilles tendon stiffness increased by 18\% (P <0:01) in the training group, but the associated reduction in strain seen during isometric contractions was not statistically significant. Tendon elongation during the stance phase of running was similar after training, but tendon recoil was reduced by 30\% (P <0:01), while estimated tendon force remained unchanged. Neither gastrocnemius medialis nor soleus fascicle shortening during stance was affected by training. Discussion These results show that a training-induced increase in Achilles tendon stiffness altered tendon behaviour during running. Despite training-induced changes in tendon mechanical properties and recoil behaviour, the data suggest that fascicle shortening patterns were preserved for the running speed that we examined. The asymmetrical changes in tendon strain patterns supports the notion that simple inseries models do not fully explain the mechanical output of the muscle-tendon unit during a complex task like running.}, language = {en} } @article{WerkhausenCroninAlbrachtetal.2019, author = {Werkhausen, Amelie and Cronin, Neil J. and Albracht, Kirsten and Bojsen-M{\o}ller, Jens and Seynnes, Olivier R.}, title = {Distinct muscle-tendon interaction during running at different speeds and in different loading conditions}, series = {Journal of Applied Physiology}, volume = {127}, journal = {Journal of Applied Physiology}, number = {1}, issn = {1522-1601}, doi = {10.1152/japplphysiol.00710.2018}, pages = {246 -- 253}, year = {2019}, language = {en} } @article{WerkhausenAlbrachtCroninetal.2017, author = {Werkhausen, Amelie and Albracht, Kirsten and Cronin, Neil J. and Meier, Rahel and Mojsen-Moeller, Jens and Seynnes, Olivier R.}, title = {Modulation of muscle-tendon interaction in the human triceps surae during an energy dissipation task}, series = {Journal of Experimental Biology}, volume = {220}, journal = {Journal of Experimental Biology}, number = {22}, issn = {0022-0949}, doi = {10.1242/jeb.164111}, pages = {4141 -- 4149}, year = {2017}, language = {en} } @article{WerkhausenAlbrachtCroninetal.2018, author = {Werkhausen, Amelie and Albracht, Kirsten and Cronin, Neil J and Paulsen, G{\o}ran and Bojsen-M{\o}ller, Jens and Seynnes, Olivier R}, title = {Effect of training-induced changes in achilles tendon stiffness on muscle-tendon behavior during landing}, series = {Frontiers in physiology}, journal = {Frontiers in physiology}, number = {9}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-042X}, doi = {10.3389/fphys.2018.00794}, pages = {11 Seiten}, year = {2018}, abstract = {During rapid deceleration of the body, tendons buffer part of the elongation of the muscle-tendon unit (MTU), enabling safe energy dissipation via eccentric muscle contraction. Yet, the influence of changes in tendon stiffness within the physiological range upon these lengthening contractions is unknown. This study aimed to examine the effect of training-induced stiffening of the Achilles tendon on triceps surae muscle-tendon behavior during a landing task. Twenty-one male subjects were assigned to either a 10-week resistance-training program consisting of single-leg isometric plantarflexion (n = 11) or to a non-training control group (n = 10). Before and after the training period, plantarflexion force, peak Achilles tendon strain and stiffness were measured during isometric contractions, using a combination of dynamometry, ultrasound and kinematics data. Additionally, testing included a step-landing task, during which joint mechanics and lengths of gastrocnemius and soleus fascicles, Achilles tendon, and MTU were determined using synchronized ultrasound, kinematics and kinetics data collection. After training, plantarflexion strength and Achilles tendon stiffness increased (15 and 18\%, respectively), and tendon strain during landing remained similar. Likewise, lengthening and negative work produced by the gastrocnemius MTU did not change detectably. However, in the training group, gastrocnemius fascicle length was offset (8\%) to a longer length at touch down and, surprisingly, fascicle lengthening and velocity were reduced by 27 and 21\%, respectively. These changes were not observed for soleus fascicles when accounting for variation in task execution between tests. These results indicate that a training-induced increase in tendon stiffness does not noticeably affect the buffering action of the tendon when the MTU is rapidly stretched. Reductions in gastrocnemius fascicle lengthening and lengthening velocity during landing occurred independently from tendon strain. Future studies are required to provide insight into the mechanisms underpinning these observations and their influence on energy dissipation.}, language = {en} } @article{WerfelGuenthnerHapfelmeieretal.2022, author = {Werfel, Stanislas and G{\"u}nthner, Roman and Hapfelmeier, Alexander and Hanssen, Henner and Kotliar, Konstantin and Heemann, Uwe and Schmaderer, Christoph}, title = {Identification of cardiovascular high-risk groups from dynamic retinal vessel signals using untargeted machine learning}, series = {Cardiovascular Research}, volume = {118}, journal = {Cardiovascular Research}, number = {2}, editor = {Guzik, Tomasz J.}, publisher = {Oxford University Press}, address = {Oxford}, issn = {0008-6363}, doi = {10.1093/cvr/cvab040}, pages = {612 -- 621}, year = {2022}, abstract = {Dynamic retinal vessel analysis (DVA) provides a non-invasive way to assess microvascular function in patients and potentially to improve predictions of individual cardiovascular (CV) risk. The aim of our study was to use untargeted machine learning on DVA in order to improve CV mortality prediction and identify corresponding response alterations.}, language = {en} } @incollection{WendorffEggertPohletal.2007, author = {Wendorff, Marion and Eggert, Thorsten and Pohl, Martina and Dresen, Carola and M{\"u}ller, Michael and Jaeger, Karl-Erich and Sprenger, Georg A. and Sch{\"u}rmann, Melanie and Sch{\"u}rmann, Martin and Johnen, Sandra and Sprenger, Gerda and Sahm, Hermann and Inoue, Tomoyuki and Sch{\"o}rken, Ulrich and Breittaupt, Holger and Fr{\"o}lich, Bettina and Heim, Petra and Iding, Hans and Juchem, Bettina and Siegert, Petra and Kula, Maria-Regina and Weckbecker, Andrea and Hummel, Werner and Fessner, Wolf-Dieter and Elling, Lothar and Wolberg, Michael and Bode, Silke and Feldmann, Ralf and Geilenkirchen, Petra and Schubert, Thomas and Walter, Lydia and D{\"u}nnwald, Thomas and Demir, Ayhan S. and Kolter-Jung, Doris and Nitsche, Adam and D{\"u}nkelmann, Pascal and Cosp, Annabel and Lingen, Bettina}, title = {Catalytic asymmetric synthesis : section 2.2}, series = {Asymmetric synthesis with chemical and biological methods / ed. by Dieter Enders ...}, booktitle = {Asymmetric synthesis with chemical and biological methods / ed. by Dieter Enders ...}, publisher = {Wiley-VCH}, address = {Weinheim}, isbn = {978-3-527-31473-7}, pages = {298 -- 413}, year = {2007}, language = {en} } @article{WendlandtKochBritzetal.2023, author = {Wendlandt, Tim and Koch, Claudia and Britz, Beate and Liedek, Anke and Schmidt, Nora and Werner, Stefan and Gleba, Yuri and Vahidpour, Farnoosh and Welden, Melanie and Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Facile Purification and Use of Tobamoviral Nanocarriers for Antibody-Mediated Display of a Two-Enzyme System}, series = {Viruses}, volume = {9}, journal = {Viruses}, number = {15}, publisher = {MDPI}, address = {Basel}, issn = {1999-4915}, doi = {doi.org/10.3390/v15091951}, pages = {Artikel 1951}, year = {2023}, abstract = {Immunosorbent turnip vein clearing virus (TVCV) particles displaying the IgG-binding domains D and E of Staphylococcus aureus protein A (PA) on every coat protein (CP) subunit (TVCVPA) were purified from plants via optimized and new protocols. The latter used polyethylene glycol (PEG) raw precipitates, from which virions were selectively re-solubilized in reverse PEG concentration gradients. This procedure improved the integrity of both TVCVPA and the wild-type subgroup 3 tobamovirus. TVCVPA could be loaded with more than 500 IgGs per virion, which mediated the immunocapture of fluorescent dyes, GFP, and active enzymes. Bi-enzyme ensembles of cooperating glucose oxidase and horseradish peroxidase were tethered together on the TVCVPA carriers via a single antibody type, with one enzyme conjugated chemically to its Fc region, and the other one bound as a target, yielding synthetic multi-enzyme complexes. In microtiter plates, the TVCVPA-displayed sugar-sensing system possessed a considerably increased reusability upon repeated testing, compared to the IgG-bound enzyme pair in the absence of the virus. A high coverage of the viral adapters was also achieved on Ta2O5 sensor chip surfaces coated with a polyelectrolyte interlayer, as a prerequisite for durable TVCVPA-assisted electrochemical biosensing via modularly IgG-assembled sensor enzymes.}, language = {en} } @article{WemhoenerHafnerSchwarzer2000, author = {Wemh{\"o}ner, Carsten and Hafner, Bernd and Schwarzer, Klemens}, title = {Simulation of solar thermal systems with CARNOT blockset in the environment MATLAB-Simulink}, pages = {1 -- 6}, year = {2000}, language = {en} } @inproceedings{WellmerChenBraunetal.2007, author = {Wellmer, Georg and Chen, B.-H. and Braun, Carsten and Ballmann, Josef}, title = {Numerical prediction of aeroelastic effects on twin-sting-rig mounted models for rear fuselage and empennage flow investigation in transonic windtunnel}, series = {Proceedings / IFASD 2007, CEAS/AIAA/KTH International Forum on Aeroelasticity and Structural Dynamics, June 18 - 21, 2007, Stockholm, Sweden}, booktitle = {Proceedings / IFASD 2007, CEAS/AIAA/KTH International Forum on Aeroelasticity and Structural Dynamics, June 18 - 21, 2007, Stockholm, Sweden}, publisher = {KTH}, address = {Stockholm}, organization = {Confederation of European Aerospace Societies ; American Institute of Aeronautics and Astronautics, Reston, Va. ; Kungliga Tekniska H{\"o}gskolan, Stockholm}, pages = {1 CD-ROM}, year = {2007}, language = {en} } @article{WeldenSchoeningWagneretal.2020, author = {Welden, Rene and Sch{\"o}ning, Michael Josef and Wagner, Patrick H. and Wagner, Torsten}, title = {Light-Addressable Electrodes for Dynamic and Flexible Addressing of Biological Systems and Electrochemical Reactions}, series = {Sensors}, volume = {20}, journal = {Sensors}, number = {6}, publisher = {MDPI}, address = {Basel}, issn = {1424-8220}, doi = {10.3390/s20061680}, pages = {Artikel 1680}, year = {2020}, abstract = {In this review article, we are going to present an overview on possible applications of light-addressable electrodes (LAE) as actuator/manipulation devices besides classical electrode structures. For LAEs, the electrode material consists of a semiconductor. Illumination with a light source with the appropiate wavelength leads to the generation of electron-hole pairs which can be utilized for further photoelectrochemical reaction. Due to recent progress in light-projection technologies, highly dynamic and flexible illumination patterns can be generated, opening new possibilities for light-addressable electrodes. A short introduction on semiconductor-electrolyte interfaces with light stimulation is given together with electrode-design approaches. Towards applications, the stimulation of cells with different electrode materials and fabrication designs is explained, followed by analyte-manipulation strategies and spatially resolved photoelectrochemical deposition of different material types.}, language = {en} } @article{WeldenSchejaSchoeningetal.2018, author = {Welden, Rene and Scheja, Sabrina and Sch{\"o}ning, Michael Josef and Wagner, Patrick and Wagner, Torsten}, title = {Electrochemical Evaluation of Light-Addressable Electrodes Based on TiO2 for the Integration in Lab-on-Chip Systems}, series = {physica status solidi a : applications and materials sciences}, volume = {215}, journal = {physica status solidi a : applications and materials sciences}, number = {15}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201800150}, pages = {Article number 1800150}, year = {2018}, abstract = {In lab-on-chip systems, electrodes are important for the manipulation (e.g., cell stimulation, electrolysis) within such systems. An alternative to commonly used electrode structures can be a light-addressable electrode. Here, due to the photoelectric effect, the conducting area can be adjusted by modification of the illumination area which enables a flexible control of the electrode. In this work, titanium dioxide based light-addressable electrodes are fabricated by a sol-gel technique and a spin-coating process, to deposit a thin film on a fluorine-doped tin oxide glass. To characterize the fabricated electrodes, the thickness, and morphological structure are measured by a profilometer and a scanning electron microscope. For the electrochemical behavior, the dark current and the photocurrent are determined for various film thicknesses. For the spatial resolution behavior, the dependency of the photocurrent while changing the area of the illuminated area is studied. Furthermore, the addressing of single fluid compartments in a three-chamber system, which is added to the electrode, is demonstrated.}, language = {en} } @article{WeldenJablonskiWegeetal.2021, author = {Welden, Rene and Jablonski, Melanie and Wege, Christina and Keusgen, Michael and Wagner, Patrick Hermann and Wagner, Torsten and Sch{\"o}ning, Michael Josef}, title = {Light-Addressable Actuator-Sensor Platform for Monitoring and Manipulation of pH Gradients in Microfluidics: A Case Study with the Enzyme Penicillinase}, series = {Biosensors}, volume = {11}, journal = {Biosensors}, number = {6}, publisher = {MDPI}, address = {Basel}, issn = {2079-6374}, doi = {10.3390/bios11060171}, pages = {Artikel 171}, year = {2021}, abstract = {The feasibility of light-addressed detection and manipulation of pH gradients inside an electrochemical microfluidic cell was studied. Local pH changes, induced by a light-addressable electrode (LAE), were detected using a light-addressable potentiometric sensor (LAPS) with different measurement modes representing an actuator-sensor system. Biosensor functionality was examined depending on locally induced pH gradients with the help of the model enzyme penicillinase, which had been immobilized in the microfluidic channel. The surface morphology of the LAE and enzyme-functionalized LAPS was studied by scanning electron microscopy. Furthermore, the penicillin sensitivity of the LAPS inside the microfluidic channel was determined with regard to the analyte's pH influence on the enzymatic reaction rate. In a final experiment, the LAE-controlled pH inhibition of the enzyme activity was monitored by the LAPS.}, language = {en} }