@article{BiselliVanderPolJokschetal.1992,
  author    = {Biselli, Manfred and Van der Pol, Jens J. and Joksch, B. and Eberhardt, R.},
  title     = {Development of an enzymatic multichannel flow injection analysis system for monitoring mammalian cell fermentations / Van der Pol, J.J.; Joksch, B.; Eberhardt, R.; Biselli, M.; Wandrey, C., Tramper, J.},
  series = {Biosensors : fundamentals, technologies and applications ; contributions to the BMFT status seminar with international participation May, 12 to 14, 1991, Internationales Bildungs-Centrum Bogensee/Brandenburg, Germany / org. by ZIM-Zentralinstitut f{\"u}r Molekularbiologie, Berlin-Buch and GBF, Braunschweig. Ed. by F. Scheller},
  journal   = {Biosensors : fundamentals, technologies and applications ; contributions to the BMFT status seminar with international participation May, 12 to 14, 1991, Internationales Bildungs-Centrum Bogensee/Brandenburg, Germany / org. by ZIM-Zentralinstitut f{\"u}r Molekularbiologie, Berlin-Buch and GBF, Braunschweig. Ed. by F. Scheller},
  publisher = {VCH},
  address   = {Weinheim},
  isbn      = {3527284370},
  pages     = {349 -- 352},
  year      = {1992},
  language  = {en}
}
@article{BiselliNoll1998,
  author    = {Biselli, Manfred and Noll, T.},
  title     = {Dielectric spectroscopy in the cultivation of suspended and immobilized hybridoma cells / Noll, T.; Biselli, M.},
  series = {Journal of Biotechnology. 63 (1998), H. 3},
  journal   = {Journal of Biotechnology. 63 (1998), H. 3},
  isbn      = {0168-1656},
  pages     = {187 -- 198},
  year      = {1998},
  language  = {en}
}
@article{BiselliSchroederHerfurthetal.1997,
  author    = {Biselli, Manfred and Schr{\"o}der, B. and Herfurth, C. and Meißner, P.},
  title     = {Differentiation of bone marrow cells immobilized on microcarriers in a fluidized bed reactor / Schr{\"o}der, B. ; Herfurth, C. ; Meißner, P. ; Biselli, M. ; Link, H. ; Wandrey, C.},
  series = {Animal cell technology : from vaccines to genetic medicine ; [Vilamoura, Portugal, May 1996] / ed. by Manuel J. T. Carrondo},
  journal   = {Animal cell technology : from vaccines to genetic medicine ; [Vilamoura, Portugal, May 1996] / ed. by Manuel J. T. Carrondo},
  publisher = {Kluwer},
  address   = {Dordrecht},
  isbn      = {0-7923-4321-2},
  pages     = {589 -- 593},
  year      = {1997},
  language  = {en}
}
@article{BaeckerDellePoghossianetal.2011,
  author    = {B{\"a}cker, Matthias and Delle, L. and Poghossian, Arshak and Biselli, Manfred and Zang, Werner and Wagner, P. and Sch{\"o}ning, Michael Josef},
  title     = {Electrochemical sensor array for bioprocess monitoring},
  series = {Electrochimica Acta (2011)},
  volume    = {56},
  journal   = {Electrochimica Acta (2011)},
  number    = {26},
  publisher = {Elsevier},
  address   = {Amsterdam},
  pages     = {9673 -- 9678},
  year      = {2011},
  language  = {en}
}
@article{SchusserBaeckerKrischeretal.2014,
  author    = {Schusser, Sebastian and B{\"a}cker, Matthias and Krischer, M. and Wenzel, L. and Leinhos, Marcel and Poghossian, Arshak and Biselli, Manfred and Wagner, P. and Sch{\"o}ning, Michael Josef},
  title     = {Enzymatically catalyzed degradation of biodegradable polymers investigated by means of a semiconductor-based field-effect sensor},
  series = {Procedia Engineering},
  volume    = {87},
  journal   = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2014.11.689},
  pages     = {1314 -- 1317},
  year      = {2014},
  abstract  = {A semiconductor field-effect device has been used for an enzymatically catalyzed degradation of biopolymers for the first time. This novel technique is capable to monitor the degradation process of multiple samples in situ and in real-time. As model system, the degradation of the biopolymer poly(D, L-lactic acid) has been monitored in the degradation medium containing the enzyme lipase from Rhizomucor miehei. The obtained results demonstrate the potential of capacitive field-effect sensors for degradation studies of biodegradable polymers.},
  language  = {en}
}
@article{TakenagaSchneiderErbayetal.2015,
  author    = {Takenaga, Shoko and Schneider, Benno and Erbay, E. and Biselli, Manfred and Schnitzler, Thomas and Sch{\"o}ning, Michael Josef and Wagner, Torsten},
  title     = {Fabrication of biocompatible lab-on-chip devices for biomedical applications by means of a 3D-printing process},
  series = {Physica status solidi (a)},
  volume    = {212},
  journal   = {Physica status solidi (a)},
  number    = {6},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201532053},
  pages     = {1347 -- 1352},
  year      = {2015},
  abstract  = {A new microfluidic assembly method for semiconductor-based biosensors using 3D-printing technologies was proposed for a rapid and cost-efficient design of new sensor systems. The microfluidic unit is designed and printed by a 3D-printer in just a few hours and assembled on a light-addressable potentiometric sensor (LAPS) chip using a photo resin. The cell growth curves obtained from culturing cells within microfluidics-based LAPS systems were compared with cell growth curves in cell culture flasks to examine biocompatibility of the 3D-printed chips. Furthermore, an optimal cell culturing within microfluidics-based LAPS chips was achieved by adjusting the fetal calf serum concentrations of the cell culture medium, an important factor for the cell proliferation.},
  language  = {en}
}
@article{BiselliLuellauWandrey1994,
  author    = {Biselli, Manfred and L{\"u}llau, E. and Wandrey, Christian},
  title     = {Growth and metabolism of CHO-cells in porous glass carriers / L{\"u}llau, E. ; Biselli, M. ; Wandrey, C.},
  series = {Animal cell technology : products of today, prospects for tomorrow ; ESACT, European Society for Animal Cell Technology, the 12th meeting / Ed. R. E. Spier},
  journal   = {Animal cell technology : products of today, prospects for tomorrow ; ESACT, European Society for Animal Cell Technology, the 12th meeting / Ed. R. E. Spier},
  publisher = {Butterworth-Heinemann},
  address   = {Oxford},
  isbn      = {0750618450},
  pages     = {252 -- 255},
  year      = {1994},
  language  = {en}
}
@article{WagnerMolinaYoshinobuetal.2007,
  author    = {Wagner, Torsten and Molina, Roberto and Yoshinobu, Tatsuo and Kloock, Joachim P. and Biselli, Manfred and Canzoneri, Michele and Schnitzler, Thomas and Sch{\"o}ning, Michael Josef},
  title     = {Handheld multi-channel LAPS device as a transducer platform for possible biological and chemical multi-sensor applications},
  series = {Electrochimica Acta. 53 (2007), H. 2},
  journal   = {Electrochimica Acta. 53 (2007), H. 2},
  isbn      = {0013-4686},
  pages     = {305 -- 311},
  year      = {2007},
  language  = {en}
}
@article{BiselliLuellauDreisbachetal.1992,
  author    = {Biselli, Manfred and L{\"u}llau, E. and Dreisbach, C. and Grogg, A.},
  title     = {Immobilization of animal cells on chemically modified siran carrier / L{\"u}llau, E. ; Dreisbach, C. ; Grogg, A. ; Biselli, M. ; Wandrey, C.},
  series = {Animal cell technology : developments, processes, and products ; ESACT, European Society for Animal Cell Technology, the 11th meeting / Ed. R. E. Spier},
  journal   = {Animal cell technology : developments, processes, and products ; ESACT, European Society for Animal Cell Technology, the 11th meeting / Ed. R. E. Spier},
  publisher = {Butterworth-Heinemann},
  address   = {Oxford},
  isbn      = {0750604212},
  pages     = {469 -- 475},
  year      = {1992},
  language  = {en}
}
@article{BiselliNollEisenkraetzeretal.2002,
  author    = {Biselli, Manfred and Noll, Thomas and Eisenkr{\"a}tzer, Detlef and Kiesewetter, Andr{\´e}},
  title     = {Improved product formation in high density Chinese hamster ovary cell cultures transfected at confluency / Thomas Noll, Detlef Eisenkr{\"a}tzer, Andr{\´e} Kiesewetter, Andr{\´e} Dinter, Steffen Zeng, Christian Wandrey, Manfred Biselli und Eric G. Berger},
  series = {Biotechnology Letters. 24 (2002), H. 11},
  journal   = {Biotechnology Letters. 24 (2002), H. 11},
  isbn      = {0141-5492},
  pages     = {861 -- 866},
  year      = {2002},
  language  = {en}
}
@article{BiselliThoemmesGarskeetal.1992,
  author    = {Biselli, Manfred and Th{\"o}mmes, J. and Garske, U. and Wandrey, Christian},
  title     = {Integrated detoxification: Reduction of ammonium concentration by dialysis with cation exchange membranes / Th{\"o}mmes, J. ; Garske, U. ; Biselli, M. ; Wandrey, C.},
  series = {Animal cell technology : developments, processes, and products ; ESACT, European Society for Animal Cell Technology, the 11th meeting / Ed. R. E. Spier},
  journal   = {Animal cell technology : developments, processes, and products ; ESACT, European Society for Animal Cell Technology, the 11th meeting / Ed. R. E. Spier},
  publisher = {Butterworth-Heinemann},
  address   = {Oxford},
  isbn      = {0750604212},
  pages     = {171 -- 175},
  year      = {1992},
  language  = {en}
}
@article{BiselliJelinekSchmidtetal.2002,
  author    = {Biselli, Manfred and Jelinek, N. and Schmidt, S. and Hilbert, U.},
  title     = {Novel bioreactors for the ex vivo cultivation of hematopoietic cells / Jelinek, N. ; Schmidt, S. ; Hilbert, U. ; Thoma, S. ; Biselli, M. ; Wandrey, C.},
  series = {Engineering in Life Sciences. 2 (2002), H. 1},
  journal   = {Engineering in Life Sciences. 2 (2002), H. 1},
  isbn      = {1618-0240},
  pages     = {15 -- 18},
  year      = {2002},
  language  = {en}
}
@article{BiselliNollWandrey1997,
  author    = {Biselli, Manfred and Noll, T. and Wandrey, C.},
  title     = {On-line biomass monitoring of immobilized hybridoma cells by dielectrical measurements / Noll, T. ; Biselli, M. ; Wandrey, C.},
  series = {Animal cell technology : from vaccines to genetic medicine ; [Vilamoura, Portugal, May 1996] / ed. by Manuel J. T. Carrondo},
  journal   = {Animal cell technology : from vaccines to genetic medicine ; [Vilamoura, Portugal, May 1996] / ed. by Manuel J. T. Carrondo},
  publisher = {Kluwer},
  address   = {Dordrecht},
  isbn      = {0-7923-4321-2},
  pages     = {289 -- 294},
  year      = {1997},
  language  = {en}
}
@article{BiselliVanderPolJokschetal.1995,
  author    = {Biselli, Manfred and Van der Pol, Jens J. and Joksch, Burkhard and Galgens, Jochem},
  title     = {On-line control of an immobilized hybridoma culture with multi-channel flow injektion analysis / Jens J. van der Pol, Burkhard Joksch, Jochem Galgens, Manfred Biselli, Cornelis D. de Gooijer, Johannes Tramper and Christian Wandrey},
  series = {Journal of Biotechnology. 43 (1995), H. 3},
  journal   = {Journal of Biotechnology. 43 (1995), H. 3},
  isbn      = {0168-1656},
  pages     = {229 -- 242},
  year      = {1995},
  language  = {en}
}
@article{BiselliVanderPolMachniketal.1997,
  author    = {Biselli, Manfred and Van der Pol, Jens J. and Machnik, Marc and Portela-Klein, Theresa},
  title     = {On-line immunoanalysis of monoclonal antibodies during a continuous culture of hybridoma cells / Jens J. van der Pol, Marc Machnik, Manfred Biselli, Theresa Portela-Klein, Cornelis D. de Gooijer, Johannes Tramper und Christian Wandrey},
  series = {Cytotechnology. 24 (1997), H. 1},
  journal   = {Cytotechnology. 24 (1997), H. 1},
  isbn      = {0920-9069},
  pages     = {19 -- 30},
  year      = {1997},
  language  = {en}
}
@article{BiselliVanderPolJokschetal.1994,
  author    = {Biselli, Manfred and Van der Pol, Jens J. and Joksch, B. and Spohn, U.},
  title     = {On-line monitoring and control of glucose, glutamine, lactate and ammonium during a high-cell-density cultivation of hybridoma cells / van der Pol, Jens J. ; Joksch, B. ; Spohn, U. ; Biselli, M. ; Wandrey, C.},
  series = {Proceedings of the sixth international meeting of the Japanese Association for Animal Cell Technology [JAACT 93]: Nagoya, Japan, November 9 - 12, 1993 / ed. by T. Kobayashi},
  journal   = {Proceedings of the sixth international meeting of the Japanese Association for Animal Cell Technology [JAACT 93]: Nagoya, Japan, November 9 - 12, 1993 / ed. by T. Kobayashi},
  publisher = {Springer Netherland},
  address   = {Berlin},
  isbn      = {0-7923-3156-7},
  pages     = {167 -- 170},
  year      = {1994},
  language  = {en}
}
@article{BiselliVanderPolSpohnetal.1994,
  author    = {Biselli, Manfred and Van der Pol, Jens J. and Spohn, Uwe and Eberhardt, Rolf},
  title     = {On-line monitoring of an animal cell culture with multi-channel flow injection analysis / van der Pol, Jens J.; Spohn, Uwe ; Eberhardt, Rolf ; G{\"a}tgens, Jochen ; Biselli, Manfred ; Wandrey, Christian ; Tramper, Johannes},
  series = {Journal of Biotechnology. 37 (1994), H. 3},
  journal   = {Journal of Biotechnology. 37 (1994), H. 3},
  isbn      = {0168-1656},
  pages     = {253 -- 264},
  year      = {1994},
  language  = {en}
}
@article{BiselliRolefDunkeretal.1994,
  author    = {Biselli, Manfred and Rolef, G. and Dunker, R. and Wandrey, Christian},
  title     = {Optimization of antibody production in a fluidized bed bioreactor / Rolef, G. ; Biselli, M. ; Dunker, R. ; Wandrey, C.},
  series = {Animal cell technology : products of today, prospects for tomorrow ; ESACT, European Society for Animal Cell Technology, the 12th meeting / Ed. R. E. Spier},
  journal   = {Animal cell technology : products of today, prospects for tomorrow ; ESACT, European Society for Animal Cell Technology, the 12th meeting / Ed. R. E. Spier},
  publisher = {Butterworth-Heinemann},
  address   = {Oxford},
  isbn      = {0750618450},
  pages     = {481 -- 484},
  year      = {1994},
  language  = {en}
}
@article{BiselliBornWandrey1995,
  author    = {Biselli, Manfred and Born, C. and Wandrey, C.},
  title     = {Oxygen transfer from the gasphase to the immobilized cells in membrane aerated fluidized beds / Born, C. ; Biselli, M. ; Wandrey, C.},
  series = {Animal cell technology : basic \& applied aspects : proceedings of the Eighth Annual Meeting of the Japanese Association for Animal Cell Technology, Iizuka, Fukuoka, Japan, November 6-10, 1995 / edited by K. Funatsu, Y. Shirai, and T. Matsushita},
  journal   = {Animal cell technology : basic \& applied aspects : proceedings of the Eighth Annual Meeting of the Japanese Association for Animal Cell Technology, Iizuka, Fukuoka, Japan, November 6-10, 1995 / edited by K. Funatsu, Y. Shirai, and T. Matsushita},
  publisher = {Kluwer Acad. Press},
  address   = {Boston},
  isbn      = {0-7923-4486-3},
  pages     = {83 -- 87},
  year      = {1995},
  language  = {en}
}
@article{BiselliZengDinteretal.1997,
  author    = {Biselli, Manfred and Zeng, Steffen and Dinter, Andre and Eisenkr{\"a}tzer, Detlef},
  title     = {Pilot Scale Expression and Purification of Soluble Protein A Tagged \&\#946;1,6N-Acetylglucosaminyltransferase in CHO Cells / Zeng, Steffen ; Dinter, Andre ; Eisenkr{\"a}tzer, Detlef ; Biselli, Manfred ; Wandrey, Christian ; Berger, Eric G.},
  series = {Biochemical and Biophysical Research Communications. 237 (1997), H. 3},
  journal   = {Biochemical and Biophysical Research Communications. 237 (1997), H. 3},
  isbn      = {0006-291X},
  pages     = {653 -- 658},
  year      = {1997},
  language  = {en}
}
@article{BiselliSchmidWandrey1988,
  author    = {Biselli, Manfred and Schmid, Georg and Wandrey, Christian},
  title     = {Preparation of cellodextrins and isolation of oligomeric side components and their characterization / Schmid, Georg ; Biselli, Manfred ; Wandrey, Christian},
  series = {Analytical Biochemistry. 175 (1988)},
  journal   = {Analytical Biochemistry. 175 (1988)},
  isbn      = {0003-2697},
  pages     = {573 -- 583},
  year      = {1988},
  language  = {en}
}
@article{BiselliBornWandrey1995,
  author    = {Biselli, Manfred and Born, C. and Wandrey, C.},
  title     = {Production of monoclonal antibodies in a pilot scale fluidized bed bioreactor / Born, C.; Biselli, M.; Wandrey, C.},
  series = {Animal cell technology : developments towards the 21st century / edited by E. C. Beuvery},
  journal   = {Animal cell technology : developments towards the 21st century / edited by E. C. Beuvery},
  publisher = {Kluwer Acad. Press},
  address   = {Dordrecht},
  isbn      = {0-7923-3736-0},
  pages     = {515 -- 519},
  year      = {1995},
  language  = {en}
}
@article{BiselliThoemmesBornetal.1995,
  author    = {Biselli, Manfred and Th{\"o}mmes, J. and Born, C. and Wandrey, C.},
  title     = {Purification of monoclonal antibodies by fluidized bed adsorption / Th{\"o}mmes, J. ; Born, C. Biselli, M. ; Wandrey, C. ; Kula, M.-R.},
  series = {Animal cell technology : developments towards the 21st century / edited by E. C. Beuvery},
  journal   = {Animal cell technology : developments towards the 21st century / edited by E. C. Beuvery},
  publisher = {Kluwer Acad. Press},
  address   = {Dordrecht},
  isbn      = {0-7923-3736-0},
  pages     = {515 -- 519},
  year      = {1995},
  language  = {en}
}
@article{BiselliKraglWandrey2002,
  author    = {Biselli, Manfred and Kragl, U. and Wandrey, C.},
  title     = {Reaction Engineering for Enzyme-Catalyzed Biotransformations},
  series = {Enzyme catalysis in organic synthesis : a comprehensive handbook. Bd. 1. - 2., completely rev. and enl. ed. / ed. by Karlheinz Drauz.},
  journal   = {Enzyme catalysis in organic synthesis : a comprehensive handbook. Bd. 1. - 2., completely rev. and enl. ed. / ed. by Karlheinz Drauz.},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  isbn      = {3-527-29949-1},
  pages     = {185 -- 257},
  year      = {2002},
  language  = {en}
}
@article{BiselliKraglWandrey1995,
  author    = {Biselli, Manfred and Kragl, U. and Wandrey, C.},
  title     = {Reaction Engineering for Enzyme-Catalyzed Biotransformations},
  series = {Enzyme catalysis in organic synthesis : a comprehensive handbook. Bd. 1. / ed. by Karlheinz Drauz.},
  journal   = {Enzyme catalysis in organic synthesis : a comprehensive handbook. Bd. 1. / ed. by Karlheinz Drauz.},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  isbn      = {3-527-28479-6},
  pages     = {89 -- 155},
  year      = {1995},
  language  = {en}
}
@article{BiselliWandrey1988,
  author    = {Biselli, Manfred and Wandrey, Christian},
  title     = {Reaction Mechanism of an Endoglucanase of Trichoderma Reesei QM 9414 using Cellodextrins as Substrate},
  series = {Technology of biological processes, safety in biotechnology, applied genetic engineering : lectures held at the 5th DECHEMA Annual Meeting of Biotechnologists, May 12 - 13, 1987, [Frankfurt, Main] / [hrsg. von Dieter Behrens ...]},
  journal   = {Technology of biological processes, safety in biotechnology, applied genetic engineering : lectures held at the 5th DECHEMA Annual Meeting of Biotechnologists, May 12 - 13, 1987, [Frankfurt, Main] / [hrsg. von Dieter Behrens ...]},
  publisher = {VCH},
  address   = {Weinheim},
  pages     = {425 -- 429},
  year      = {1988},
  language  = {en}
}
@article{BiselliThoemmesGaetgensetal.1993,
  author    = {Biselli, Manfred and Th{\"o}mmes, J. and G{\"a}tgens, J. and Runstadler, P. W.},
  title     = {The influence of dissolved oxygen tension on the metabolic activity of an immobilized hybridoma population / Th{\"o}mmes, J. ; G{\"a}tgens, J. ; Biselli, M. ; Runstadler, P.W. ; Wandrey, C.},
  series = {Cytotechnology . 13 (1993), H. 1},
  journal   = {Cytotechnology . 13 (1993), H. 1},
  isbn      = {0920-9069},
  pages     = {29 -- 39},
  year      = {1993},
  language  = {en}
}
@article{TakenagaBiselliSchnitzleretal.2014,
  author    = {Takenaga, Shoko and Biselli, Manfred and Schnitzler, Thomas and {\"O}hlschl{\"a}ger, Peter and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Toward multi-analyte bioarray sensors: LAPS-based on-chip determination of a Michaelis-Menten-like kinetics for cell culturing},
  series = {Physica status solidi A : Applications and materials science},
  volume    = {211},
  journal   = {Physica status solidi A : Applications and materials science},
  number    = {6},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-396X (E); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)},
  doi       = {10.1002/pssa.201330464},
  pages     = {1410 -- 1415},
  year      = {2014},
  abstract  = {The metabolic activity of Chinese hamster ovary (CHO) cells was observed using a light-addressable potentiometric sensor (LAPS). The dependency toward different glucose concentrations (17-200 mM) follows a Michaelis-Menten kinetics trajectory with Kₘ = 32.8 mM, and the obtained Kₘ value in this experiment was compared with that found in literature. In addition, the pH shift induced by glucose metabolism of tumor cells transfected with the HPV-16 genome (C3 cells) was successfully observed. These results indicate the possibility to determine the tumor cells metabolism with a LAPS-based measurement device.},
  language  = {en}
}