@article{Stulpe2020, author = {Stulpe, Werner}, title = {Pairwise coexistence of effects versus coexistence}, series = {Journal of Physics: Conference Series}, volume = {1638}, journal = {Journal of Physics: Conference Series}, number = {012004}, publisher = {IOP}, address = {Bristol}, issn = {1742-6596}, doi = {10.1088/1742-6596/1638/1/012004}, pages = {1 -- 21}, year = {2020}, language = {en} } @article{GossmannThomasHorvathetal.2020, author = {Gossmann, Matthias and Thomas, Ulrich and Horv{\´a}th, Andr{\´a}s and Dragicevic, Elena and Stoelzle-Feix, Sonja and Jung, Alexander and Raman, Aravind Hariharan and Staat, Manfred and Linder, Peter}, title = {A higher-throughput approach to investigate cardiac contractility in vitro under physiological mechanical conditions}, series = {Journal of Pharmacological and Toxicological Methods}, volume = {105}, journal = {Journal of Pharmacological and Toxicological Methods}, number = {Article 106843}, publisher = {Elsevier}, address = {New York, NY}, doi = {10.1016/j.vascn.2020.106843}, year = {2020}, language = {en} } @article{PoghossianJablonskiMolinnusetal.2020, author = {Poghossian, Arshak and Jablonski, Melanie and Molinnus, Denise and Wege, Christina and Sch{\"o}ning, Michael Josef}, title = {Field-Effect Sensors for Virus Detection: From Ebola to SARS-CoV-2 and Plant Viral Enhancers}, series = {Frontiers in Plant Science}, volume = {11}, journal = {Frontiers in Plant Science}, number = {Article 598103}, publisher = {Frontiers}, address = {Lausanne}, doi = {10.3389/fpls.2020.598103}, pages = {1 -- 14}, year = {2020}, abstract = {Coronavirus disease 2019 (COVID-19) is a novel human infectious disease provoked by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, no specific vaccines or drugs against COVID-19 are available. Therefore, early diagnosis and treatment are essential in order to slow the virus spread and to contain the disease outbreak. Hence, new diagnostic tests and devices for virus detection in clinical samples that are faster, more accurate and reliable, easier and cost-efficient than existing ones are needed. Due to the small sizes, fast response time, label-free operation without the need for expensive and time-consuming labeling steps, the possibility of real-time and multiplexed measurements, robustness and portability (point-of-care and on-site testing), biosensors based on semiconductor field-effect devices (FEDs) are one of the most attractive platforms for an electrical detection of charged biomolecules and bioparticles by their intrinsic charge. In this review, recent advances and key developments in the field of label-free detection of viruses (including plant viruses) with various types of FEDs are presented. In recent years, however, certain plant viruses have also attracted additional interest for biosensor layouts: Their repetitive protein subunits arranged at nanometric spacing can be employed for coupling functional molecules. If used as adapters on sensor chip surfaces, they allow an efficient immobilization of analyte-specific recognition and detector elements such as antibodies and enzymes at highest surface densities. The display on plant viral bionanoparticles may also lead to long-time stabilization of sensor molecules upon repeated uses and has the potential to increase sensor performance substantially, compared to conventional layouts. This has been demonstrated in different proof-of-concept biosensor devices. Therefore, richly available plant viral particles, non-pathogenic for animals or humans, might gain novel importance if applied in receptor layers of FEDs. These perspectives are explained and discussed with regard to future detection strategies for COVID-19 and related viral diseases.}, language = {en} } @article{FingerBraunBil2020, author = {Finger, Felix and Braun, Carsten and Bil, Cees}, title = {Comparative assessment of parallel-hybrid-electric propulsion systems for four different aircraft}, series = {Journal of Aircraft}, volume = {57}, journal = {Journal of Aircraft}, number = {5}, publisher = {AIAA}, address = {Reston, Va.}, issn = {1533-3868}, doi = {10.2514/1.C035897}, year = {2020}, abstract = {Until electric energy storage systems are ready to allow fully electric aircraft, the combination of combustion engine and electric motor as a hybrid-electric propulsion system seems to be a promising intermediate solution. Consequently, the design space for future aircraft is expanded considerably, as serial hybrid-electric, parallel hybrid-electric, fully electric, and conventional propulsion systems must all be considered. While the best propulsion system depends on a multitude of requirements and considerations, trends can be observed for certain types of aircraft and certain types of missions. This Paper provides insight into some factors that drive a new design toward either conventional or hybrid propulsion systems. General aviation aircraft, regional transport aircraft vertical takeoff and landing air taxis, and unmanned aerial vehicles are chosen as case studies. Typical missions for each class are considered, and the aircraft are analyzed regarding their takeoff mass and primary energy consumption. For these case studies, a high-level approach is chosen, using an initial sizing methodology. Only parallel-hybrid-electric powertrains are taken into account. Aeropropulsive interaction effects are neglected. Results indicate that hybrid-electric propulsion systems should be considered if the propulsion system is sized by short-duration power constraints. However, if the propulsion system is sized by a continuous power requirement, hybrid-electric systems offer hardly any benefit.}, language = {en} } @article{Golland2020, author = {Golland, Alexander}, title = {Datenschutzrechtliche Fragen personalisierter Preise — Herausforderungen von Algorithmen im Schnittbereich von Ethik, {\"O}konomie und Datenschutz}, series = {CR Computer und Recht}, volume = {36}, journal = {CR Computer und Recht}, number = {3}, publisher = {Verlag Dr. Otto Schmidt}, address = {K{\"o}ln}, isbn = {2194-4172}, doi = {10.9785/cr-2020-360313}, pages = {186 -- 194}, year = {2020}, language = {de} } @article{OezsoyluKizildagSchoeningetal.2020, author = {{\"O}zsoylu, Dua and Kizildag, Sefa and Sch{\"o}ning, Michael Josef and Wagner, Torsten}, title = {Differential chemical imaging of extracellular acidification within microfluidic channels using a plasma-functionalized light-addressable potentiometric sensor (LAPS)}, series = {Physics in Medicine}, volume = {10}, journal = {Physics in Medicine}, number = {100030}, publisher = {Elsevier}, address = {Amsterdam}, issn = {2352-4510}, doi = {10.1016/j.phmed.2020.100030}, pages = {8}, year = {2020}, abstract = {Extracellular acidification is a basic indicator for alterations in two vital metabolic pathways: glycolysis and cellular respiration. Measuring these alterations by monitoring extracellular acidification using cell-based biosensors such as LAPS plays an important role in studying these pathways whose disorders are associated with numerous diseases including cancer. However, the surface of the biosensors must be specially tailored to ensure high cell compatibility so that cells can represent more in vivo-like behavior, which is critical to gain more realistic in vitro results from the analyses, e.g., drug discovery experiments. In this work, O2 plasma patterning on the LAPS surface is studied to enhance surface features of the sensor chip, e.g., wettability and biofunctionality. The surface treated with O2 plasma for 30 s exhibits enhanced cytocompatibility for adherent CHO-K1 cells, which promotes cell spreading and proliferation. The plasma-modified LAPS chip is then integrated into a microfluidic system, which provides two identical channels to facilitate differential measurements of the extracellular acidification of CHO-K1 cells. To the best of our knowledge, it is the first time that extracellular acidification within microfluidic channels is quantitatively visualized as differential (bio-)chemical images.}, language = {en} } @article{MartinVaqueroKleefeld2020, author = {Mart{\´i}n-Vaquero, J. and Kleefeld, Andreas}, title = {Solving nonlinear parabolic PDEs in several dimensions: Parallelized ESERK codes}, series = {Journal of Computational Physics}, journal = {Journal of Computational Physics}, number = {423}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0021-9991}, doi = {10.1016/j.jcp.2020.109771}, year = {2020}, abstract = {There is a very large number of very important situations which can be modeled with nonlinear parabolic partial differential equations (PDEs) in several dimensions. In general, these PDEs can be solved by discretizing in the spatial variables and transforming them into huge systems of ordinary differential equations (ODEs), which are very stiff. Therefore, standard explicit methods require a large number of iterations to solve stiff problems. But implicit schemes are computationally very expensive when solving huge systems of nonlinear ODEs. Several families of Extrapolated Stabilized Explicit Runge-Kutta schemes (ESERK) with different order of accuracy (3 to 6) are derived and analyzed in this work. They are explicit methods, with stability regions extended, along the negative real semi-axis, quadratically with respect to the number of stages s, hence they can be considered to solve stiff problems much faster than traditional explicit schemes. Additionally, they allow the adaptation of the step length easily with a very small cost. Two new families of ESERK schemes (ESERK3 and ESERK6) are derived, and analyzed, in this work. Each family has more than 50 new schemes, with up to 84.000 stages in the case of ESERK6. For the first time, we also parallelized all these new variable step length and variable number of stages algorithms (ESERK3, ESERK4, ESERK5, and ESERK6). These parallelized strategies allow to decrease times significantly, as it is discussed and also shown numerically in two problems. Thus, the new codes provide very good results compared to other well-known ODE solvers. Finally, a new strategy is proposed to increase the efficiency of these schemes, and it is discussed the idea of combining ESERK families in one code, because typically, stiff problems have different zones and according to them and the requested tolerance the optimum order of convergence is different.}, language = {en} } @article{Gaigall2020, author = {Gaigall, Daniel}, title = {Rothman-Woodroofe symmetry test statistic revisited}, series = {Computational Statistics \& Data Analysis}, volume = {2020}, journal = {Computational Statistics \& Data Analysis}, number = {142}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0167-9473}, doi = {10.1016/j.csda.2019.106837}, pages = {Artikel 106837}, year = {2020}, abstract = {The Rothman-Woodroofe symmetry test statistic is revisited on the basis of independent but not necessarily identically distributed random variables. The distribution-freeness if the underlying distributions are all symmetric and continuous is obtained. The results are applied for testing symmetry in a meta-analysis random effects model. The consistency of the procedure is discussed in this situation as well. A comparison with an alternative proposal from the literature is conducted via simulations. Real data are analyzed to demonstrate how the new approach works in practice.}, language = {en} } @article{Gaigall2020, author = {Gaigall, Daniel}, title = {Testing marginal homogeneity of a continuous bivariate distribution with possibly incomplete paired data}, series = {Metrika}, volume = {2020}, journal = {Metrika}, number = {83}, publisher = {Springer}, issn = {1435-926X}, doi = {10.1007/s00184-019-00742-5}, pages = {437 -- 465}, year = {2020}, abstract = {We discuss the testing problem of homogeneity of the marginal distributions of a continuous bivariate distribution based on a paired sample with possibly missing components (missing completely at random). Applying the well-known two-sample Cr{\´a}mer-von-Mises distance to the remaining data, we determine the limiting null distribution of our test statistic in this situation. It is seen that a new resampling approach is appropriate for the approximation of the unknown null distribution. We prove that the resulting test asymptotically reaches the significance level and is consistent. Properties of the test under local alternatives are pointed out as well. Simulations investigate the quality of the approximation and the power of the new approach in the finite sample case. As an illustration we apply the test to real data sets.}, language = {en} } @article{DrummEmhardtKoketal.2020, author = {Drumm, Christian and Emhardt, Selina N. and Kok, Ellen M. and Jarodzka, Halzka and Brand-Gruwel, Saskia and van Gog, Tamara}, title = {How Experts Adapt Their Gaze Behavior When Modeling a Task to Novices}, series = {Cognitive science}, volume = {44}, journal = {Cognitive science}, number = {9}, publisher = {Wiley}, address = {Weinheim}, issn = {1551-6709}, doi = {10.1111/cogs.12893}, pages = {26}, year = {2020}, abstract = {Domain experts regularly teach novice students how to perform a task. This often requires them to adjust their behavior to the less knowledgeable audience and, hence, to behave in a more didactic manner. Eye movement modeling examples (EMMEs) are a contemporary educational tool for displaying experts' (natural or didactic) problem-solving behavior as well as their eye movements to learners. While research on expert-novice communication mainly focused on experts' changes in explicit, verbal communication behavior, it is as yet unclear whether and how exactly experts adjust their nonverbal behavior. This study first investigated whether and how experts change their eye movements and mouse clicks (that are displayed in EMMEs) when they perform a task naturally versus teach a task didactically. Programming experts and novices initially debugged short computer codes in a natural manner. We first characterized experts' natural problem-solving behavior by contrasting it with that of novices. Then, we explored the changes in experts' behavior when being subsequently instructed to model their task solution didactically. Experts became more similar to novices on measures associated with experts' automatized processes (i.e., shorter fixation durations, fewer transitions between code and output per click on the run button when behaving didactically). This adaptation might make it easier for novices to follow or imitate the expert behavior. In contrast, experts became less similar to novices for measures associated with more strategic behavior (i.e., code reading linearity, clicks on run button) when behaving didactically.}, language = {en} } @article{KleefeldPieronek2020, author = {Kleefeld, Andreas and Pieronek, J.}, title = {Elastic transmission eigenvalues and their computation via the method of fundamental solutions}, series = {Applicable Analysis}, volume = {100}, journal = {Applicable Analysis}, number = {16}, publisher = {Taylore \& Francis}, address = {London}, issn = {1563-504X}, doi = {10.1080/00036811.2020.1721473}, pages = {3445 -- 3462}, year = {2020}, abstract = {A stabilized version of the fundamental solution method to catch ill-conditioning effects is investigated with focus on the computation of complex-valued elastic interior transmission eigenvalues in two dimensions for homogeneous and isotropic media. Its algorithm can be implemented very shortly and adopts to many similar partial differential equation-based eigenproblems as long as the underlying fundamental solution function can be easily generated. We develop a corroborative approximation analysis which also implicates new basic results for transmission eigenfunctions and present some numerical examples which together prove successful feasibility of our eigenvalue recovery approach.}, language = {en} } @article{Golland2020, author = {Golland, Alexander}, title = {Die „private" Datenverarbeitung im Internet. Verantwortlichkeiten und Rechtm{\"a}ßigkeit bei Nutzung von Plattformdiensten durch nat{\"u}rliche Personen}, series = {ZD Zeitschrift f{\"u}r Datenschutz}, volume = {10}, journal = {ZD Zeitschrift f{\"u}r Datenschutz}, number = {8}, editor = {Hoeren, Thomas and Schneider, Jochen and Selmayr, Martin and Spies, Axel and Wybitul, Tim}, publisher = {Beck}, address = {M{\"u}nchen}, isbn = {2192-5593}, pages = {397 -- 403}, year = {2020}, language = {de} } @article{Golland2020, author = {Golland, Alexander}, title = {Weckruf f{\"u}r deutsche Großunternehmen? - Der neue Entwurf des IT-Sicherheitsgesetz 2.0}, series = {K\&R Kommunikation \& Recht}, volume = {23}, journal = {K\&R Kommunikation \& Recht}, number = {7-8}, publisher = {DFV Mediengruppe}, address = {Frankfurt a.M.}, isbn = {1434-6354}, pages = {I}, year = {2020}, language = {de} } @article{HoffstadtPohenDickeetal.2020, author = {Hoffstadt, Kevin and Pohen, Gino D. and Dicke, Max D. and Paulsen, Svea and Krafft, Simone and Zang, Joachim W. and Fonseca-Zang, Warde A. da and Leite, Athaydes and Kuperjans, Isabel}, title = {Challenges and prospects of biogas from energy cane as supplement to bioethanol production}, series = {Agronomy}, volume = {10}, journal = {Agronomy}, number = {6}, publisher = {MDPI}, address = {Basel}, issn = {2073-4395}, doi = {10.3390/agronomy10060821}, year = {2020}, abstract = {Innovative breeds of sugar cane yield up to 2.5 times as much organic matter as conventional breeds, resulting in a great potential for biogas production. The use of biogas production as a complementary solution to conventional and second-generation ethanol production in Brazil may increase the energy produced per hectare in the sugarcane sector. Herein, it was demonstrated that through ensiling, energy cane can be conserved for six months; the stored cane can then be fed into a continuous biogas process. This approach is necessary to achieve year-round biogas production at an industrial scale. Batch tests revealed specific biogas potentials between 400 and 600 LN/kgVS for both the ensiled and non-ensiled energy cane, and the specific biogas potential of a continuous biogas process fed with ensiled energy cane was in the same range. Peak biogas losses through ensiling of up to 27\% after six months were observed. Finally, compared with second-generation ethanol production using energy cane, the results indicated that biogas production from energy cane may lead to higher energy yields per hectare, with an average energy yield of up to 162 MWh/ha. Finally, the Farm²CBG concept is introduced, showing an approach for decentralized biogas production.}, language = {en} } @article{BreussKleefeld2020, author = {Breuß, Michael and Kleefeld, Andreas}, title = {Implicit monotone difference methods for scalar conservation laws with source terms}, series = {Acta Mathematica Vietnamica}, volume = {45}, journal = {Acta Mathematica Vietnamica}, publisher = {Springer Singapore}, address = {Singapore}, issn = {2315-4144}, doi = {10.1007/s40306-019-00354-1}, pages = {709 -- 738}, year = {2020}, abstract = {In this article, a concept of implicit methods for scalar conservation laws in one or more spatial dimensions allowing also for source terms of various types is presented. This material is a significant extension of previous work of the first author (Breuß SIAM J. Numer. Anal. 43(3), 970-986 2005). Implicit notions are developed that are centered around a monotonicity criterion. We demonstrate a connection between a numerical scheme and a discrete entropy inequality, which is based on a classical approach by Crandall and Majda. Additionally, three implicit methods are investigated using the developed notions. Next, we conduct a convergence proof which is not based on a classical compactness argument. Finally, the theoretical results are confirmed by various numerical tests.}, language = {en} } @article{Gaigall2020, author = {Gaigall, Daniel}, title = {Hoeffding-Blum-Kiefer-Rosenblatt independence test statistic on partly not identically distributed data}, series = {Communications in Statistics - Theory and Methods}, volume = {51}, journal = {Communications in Statistics - Theory and Methods}, number = {12}, publisher = {Taylor \& Francis}, address = {London}, issn = {1532-415X}, doi = {10.1080/03610926.2020.1805767}, pages = {4006 -- 4028}, year = {2020}, abstract = {The established Hoeffding-Blum-Kiefer-Rosenblatt independence test statistic is investigated for partly not identically distributed data. Surprisingly, it turns out that the statistic has the well-known distribution-free limiting null distribution of the classical criterion under standard regularity conditions. An application is testing goodness-of-fit for the regression function in a non parametric random effects meta-regression model, where the consistency is obtained as well. Simulations investigate size and power of the approach for small and moderate sample sizes. A real data example based on clinical trials illustrates how the test can be used in applications.}, language = {en} } @article{BiewendtBlaschkeBoehnert2020, author = {Biewendt, Marcel and Blaschke, Florian and B{\"o}hnert, Arno}, title = {The rebound effect - a systematic review of the current state of affairs}, series = {European Journal of Economics and Business Studies}, volume = {6}, journal = {European Journal of Economics and Business Studies}, number = {1}, publisher = {Revistia}, address = {London}, issn = {2601-8659}, doi = {10.26417/134nvy47z}, pages = {106 -- 120}, year = {2020}, abstract = {This publication is intended to present the current state of research on the rebound effect. First, a systematic literature review is carried out to outline (current) scientific models and theories. Research Question 1 follows with a mathematical introduction of the rebound effect, which shows the interdependence of consumer behaviour, technological progress, and interwoven effects for both. Thereupon, the research field is analysed for gaps and limitations by a systematic literature review. To ensure quantitative and qualitative results, a review protocol is used that integrates two different stages and covers all relevant publications released between 2000 and 2019. Accordingly, 392 publications were identified that deal with the rebound effect. These papers were reviewed to obtain relevant information on the two research questions. The literature review shows that research on the rebound effect is not yet comprehensive and focuses mainly on the effect itself rather than solutions to avoid it. Research Question 2 finds that the main gap, and thus the limitations, is that not much research has been published on the actual avoidance of the rebound effect yet. This is a major limitation for practical application by decision-makers and politicians. Therefore, a theoretical analysis was carried out to identify potential theories and ideas to avoid the rebound effect. The most obvious idea to solve this problem is the theory of a Steady-State Economy (SSE), which has been described and reviewed.}, language = {en} } @article{MeyerHaenelBeehetal.2020, author = {Meyer, S. and H{\"a}nel, Matthias and Beeh, B. and Dittmann-Gabriel, S{\"o}ren and Dluhosch, R. and May, Martin and Herrmann, Ulf}, title = {Multifunktionaler thermischer Stromspeicher f{\"u}r die Strom- und W{\"a}rmeversorgung der Industrie von morgen}, series = {ETG Journal / Energietechnische Gesellschaft im VDE (ETG)}, volume = {2020}, journal = {ETG Journal / Energietechnische Gesellschaft im VDE (ETG)}, number = {1}, issn = {2625-9907}, pages = {6 -- 9}, year = {2020}, language = {de} } @article{PetersonOsterPeterson2020, author = {Peterson-Oster, Madeleine and Peterson, Leif Arne}, title = {Gewerbebau: Modellprojekt mit neuem elementiertem, freistehendem Fassadensystem}, series = {Bauen mit Holz, Der Zimmermann}, journal = {Bauen mit Holz, Der Zimmermann}, publisher = {Rudolf M{\"u}ller}, address = {K{\"o}ln}, issn = {0005-6545}, year = {2020}, abstract = {Die im Zuge einer Betriebs{\"u}bergabe anstehende Baumaßnahmen am eigenen B{\"u}ro- und Produktionsgeb{\"a}ude boten ideale Voraussetzung zur Anwendung einer raum­-kreierenden Außenhaut. Mit der elementierten, freistehenden Eichenholz-Fassade wurde ein bis dahin weitgehend funktionales Bauwerk substanzschonend und zugleich optisch ansprechender umgestaltet.}, language = {de} } @article{PetersonOsterPeterson2020, author = {Peterson-Oster, Madeleine and Peterson, Leif Arne}, title = {Fassadensystem: Optisch ansprechend, freistehend, elementiert und aus Eichenholz}, series = {Bauen mit Holz, Der Zimmermann}, journal = {Bauen mit Holz, Der Zimmermann}, publisher = {Rudolf M{\"u}ller}, address = {K{\"o}ln}, issn = {0005-6545}, year = {2020}, abstract = {Bei der Entwicklung des Fassadensystems ging es darum die m{\"o}gliche Dauerhaftigkeit von Holz bei direkter Bewitterung zu maximieren. Gleichzeitig soll gezeigt werden, dass mittels durchdachter Ans{\"a}tze beim konstruktiven Holzschutz und die Wahl einer geeigneten Holzart langlebige Konstruktionen realisiert werden k{\"o}nnen.}, language = {de} } @article{FinkenbergerVeil2020, author = {Finkenberger, Isabel Maria and Veil, Katja}, title = {R{\"a}umliche Transformation}, series = {RaumPlanung : Fachzeitschrift f{\"u}r r{\"a}umliche Planung und Forschung}, volume = {205}, journal = {RaumPlanung : Fachzeitschrift f{\"u}r r{\"a}umliche Planung und Forschung}, number = {1}, publisher = {IfR (Informationskreis f{\"u}r Raumplanung)}, address = {Dortmund}, issn = {0176-7534}, pages = {6 -- 11}, year = {2020}, language = {de} } @article{Biewendt2020, author = {Biewendt, Marcel}, title = {Sustainable development: A quantitative analysis regarding the impact of resource rents on state welfare from 2002 to 2017}, series = {SocioEconomic Challenges}, volume = {4}, journal = {SocioEconomic Challenges}, number = {4}, publisher = {ARMG Publishing}, address = {Sumy}, issn = {2520-6214}, doi = {10.21272/sec.4(4).119-131.2020}, pages = {119 -- 131}, year = {2020}, abstract = {This paper uses a quantitative analysis to examine the interdependence and impact of resource rents on socio-economic development from 2002 to 2017. Nigeria and Norway have been chosen as reference countries due to their abundance of natural resources by similar economic performance, while the ranking in the Human Development Index differs dramatically. As the Human Development Index provides insight into a country's cultural and socio-economic characteristics and development in addition to economic indicators, it allows a comparison of the two countries. The hypothesis presented and discussed in this paper was researched before. A qualitative research approach was used in the author's master's thesis "The Human Development Index (HDI) as a Reflection of Resource Abundance (using Nigeria and Norway as a case study)" in 2018. The management of scarce resources is an important aspect in the development of modern countries and those on the threshold of becoming industrialised nations. The effects of a mistaken resource management are not only of a purely economic nature but also of a social and socio-economic nature. In order to present a partial aspect of these dependencies and influences this paper uses a quantitative analysis to examine the interdependence and impact of resource rents on socio-economic development from 2002 to 2017. Nigeria and Norway have been chosen as reference countries due to their abundance of natural resources by similar economic performance, while the ranking in the Human Development Index differs significantly. As the Human Development Index provides insight into a country's cultural and socio-economic characteristics and development in addition to economic indicators, it allows a comparison of the two countries. This paper found out in a holistic perspective that (not or poorly managed) resource wealth in itself has a negative impact on socio-economic development and significantly reduces the productivity of the citizens of a state. This is expressed in particular for the years 2002 till 2017 in a negative correlation of GDP per capita and HDI value with the share respectively the size of resources in the GDP of a country.}, language = {en} } @article{StapenhorstDutto2020, author = {Stapenhorst, Carolin and Dutto, Andrea Alberto}, title = {Turin: Industriedenkmal wird Kulturzentrum wird Lazarett}, series = {Bauwelt}, volume = {111}, journal = {Bauwelt}, number = {13}, publisher = {Bauverlag BV}, address = {G{\"u}tersloh}, issn = {0005-6855}, pages = {56 -- 59}, year = {2020}, language = {de} } @article{BiewendtBlaschkeBoehnert2020, author = {Biewendt, Marcel and Blaschke, Florian and B{\"o}hnert, Arno}, title = {An evaluation of corporate sustainability in context of the Jevons paradox}, series = {SocioEconomic Challenges}, volume = {4}, journal = {SocioEconomic Challenges}, number = {3}, publisher = {ARMG Publishing}, address = {Sumy}, issn = {2520-6214}, doi = {10.21272/sec.4(3).46-65.2020}, pages = {46 -- 65}, year = {2020}, abstract = {The successful implementation and continuous development of sustainable corporate-level solutions is a challenge. These are endeavours in which social, environmental, and financial aspects must be weighed against each other. They can prove difficult to handle and, in some cases, almost unrealistic. Concepts such as green controlling, IT, and manufacturing look promising and are constantly evolving. This paper aims to achieve a better understanding of the field of corporate sustainability (CS). It will evaluate the hypothesis by which Corporate Sustainability thrives, via being efficient, increasing the performance, and raising the value of the input of the enterprises to the resources used. In fact, Corporate Sustainability on the surface could seem to contradict the idea, which supports the understanding that it encourages the reduction of the heavy reliance on the use of natural resources, the overall environmental impact, and above all, their protection. To understand how the contradictory notion of CS came about, in this part of the paper, the emphasis is placed on providing useful insight to this regard. The first part of this paper summarizes various definitions, organizational theories, and measures used for CS and its derivatives like green controlling, IT, and manufacturing. Second, a case study is given that combines the aforementioned sustainability models. In addition to evaluating the hypothesis, the overarching objective of this paper is to demonstrate the use of green controlling, IT, and manufacturing in the corporate sector. Furthermore, this paper outlines the current challenges and possible directions for CS in the future.}, language = {en} } @article{BiewendtBoehnertBlaschke2020, author = {Biewendt, Marcel and B{\"o}hnert, Arno and Blaschke, Florian}, title = {The repercussions of the digital twin in the automotive industry on the new marketing logic}, series = {European Journal of Marketing and Economics}, volume = {4}, journal = {European Journal of Marketing and Economics}, number = {1}, publisher = {Revistia}, address = {London}, issn = {2601-8659}, doi = {10.26417/229eim64f}, pages = {68 -- 73}, year = {2020}, abstract = {Rapid development of virtual and data acquisition technology makes Digital Twin Technology (DT) one of the fundamental areas of research, while DT is one of the most promissory developments for the achievement of Industry 4.0. 48\% percent of organisations implementing the Internet of Things are already using DT or plan to use DT in 2020. The global market for DT is expected to grow by 38 percent annually, reaching USD16 billion by 2023. In addition, the number of participating organisations using digital twins is expected to triple by 2022. DTs are characterised by the integration between physical and virtual spaces. The driving idea for DT is to develop, test and build our devices in a virtual environment. The objective of this paper is to study the impact of DT in the automotive industry on the new marketing logic. This paper outlines the current challenges and possible directions for the future DT in marketing. This paper will be helpful for managers in the industry to use the advantages and potentials of DT.}, language = {en} } @article{RaffeisAdjeiKyeremehVroomenetal.2020, author = {Raffeis, Iris and Adjei-Kyeremeh, Frank and Vroomen, Uwe and Westhoff, Elmar and Bremen, Sebastian and Hohoi, Alexandru and B{\"u}hrig-Polaczek, Andreas}, title = {Qualification of a Ni-Cu alloy for the laser powder bed fusion process (LPBF): Its microstructure and mechanical properties}, series = {Applied Sciences}, volume = {10}, journal = {Applied Sciences}, number = {Art. 3401}, publisher = {MDPI}, address = {Basel}, issn = {2076-3417}, doi = {10.3390/app10103401}, pages = {1 -- 15}, year = {2020}, abstract = {As researchers continue to seek the expansion of the material base for additive manufacturing, there is a need to focus attention on the Ni-Cu group of alloys which conventionally has wide industrial applications. In this work, the G-NiCu30Nb casting alloy, a variant of the Monel family of alloys with Nb and high Si content is, for the first time, processed via the laser powder bed fusion process (LPBF). Being novel to the LPBF processes, optimum LPBF parameters were determined, and hardness and tensile tests were performed in as-built conditions and after heat treatment at 1000 °C. Microstructures of the as-cast and the as-built condition were compared. Highly dense samples (99.8\% density) were achieved after varying hatch distance (80 µm and 140 µm) with scanning speed (550 mm/s-1500 mm/s). There was no significant difference in microhardness between varied hatch distance print sets. Microhardness of the as-built condition (247 HV0.2) exceeded the as-cast microhardness (179 HV0.2.). Tensile specimens built in vertical (V) and horizontal (H) orientations revealed degrees of anisotropy and were superior to conventionally reported figures. Post heat treatment increased ductility from 20\% to 31\% (V), as well as from 16\% to 25\% (H), while ultimate tensile strength (UTS) and yield strength (YS) were considerably reduced.}, language = {en} } @article{AsarStapenhorst2020, author = {Asar, Hande and Stapenhorst, Carolin}, title = {Zvi Hecker: Drawing on drawing}, series = {Archives of Design Research}, volume = {33}, journal = {Archives of Design Research}, number = {3}, publisher = {Korean Society of Design Science}, address = {Seongnam}, issn = {1226-8046}, doi = {10.15187/adr.2020.08.33.3.45}, pages = {45 -- 53}, year = {2020}, abstract = {Background: Architectural representation, nurtured by the interaction between design thinking and design action, is inherently multi-layered. However, the representation object cannot always reflect these layers. Therefore, it is claimed that these reflections and layerings can gain visibility through 'performativity in personal knowledge', which basically has a performative character. The specific layers of representation produced during the performativity in personal knowledge permit insights about the 'personal way of designing' [1]. Therefore, the question, 'how can these layered drawings be decomposed to understand the personal way of designing', can be defined as the beginning of the study. On the other hand, performativity in personal knowledge in architectural design is handled through the relationship between explicit and tacit knowledge and representational and non-representational theory. To discuss the practical dimension of these theoretical relations, Zvi Hecker's drawing of the Heinz-Galinski-School is examined as an example. The study aims to understand the relationships between the layers by decomposing a layered drawing analytically in order to exemplify personal ways of designing. Methods: The study is based on qualitative research methodologies. First, a model has been formed through theoretical readings to discuss the performativity in personal knowledge. This model is used to understand the layered representations and to research the personal way of designing. Thus, one drawing of Hecker's Heinz-Galinski-School project is chosen. Second, its layers are decomposed to detect and analyze diverse objects, which hint to different types of design tools and their application. Third, Zvi Hecker's statements of the design process are explained through the interview data [2] and other sources. The obtained data are compared with each other. Results: By decomposing the drawing, eleven layers are defined. These layers are used to understand the relation between the design idea and its representation. They can also be thought of as a reading system. In other words, a method to discuss Hecker's performativity in personal knowledge is developed. Furthermore, the layers and their interconnections are described in relation to Zvi Hecker's personal way of designing. Conclusions: It can be said that layered representations, which are associated with the multilayered structure of performativity in personal knowledge, form the personal way of designing.}, language = {en} } @article{KezerashviliDachwald2021, author = {Kezerashvili, Roman Ya and Dachwald, Bernd}, title = {Preface: Solar sailing: Concepts, technology, and missions II}, series = {Advances in Space Research}, volume = {67}, journal = {Advances in Space Research}, number = {9}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0273-1177}, doi = {10.1016/j.asr.2021.01.037}, pages = {2559 -- 2560}, year = {2021}, language = {en} } @article{SpietzSproewitzSeefeldtetal.2021, author = {Spietz, Peter and Spr{\"o}witz, Tom and Seefeldt, Patric and Grundmann, Jan Thimo and Jahnke, Rico and Mikschl, Tobias and Mikulz, Eugen and Montenegro, Sergio and Reershemius, Siebo and Renger, Thomas and Ruffer, Michael and Sasaki, Kaname and Sznajder, Maciej and T{\´o}th, Norbert and Ceriotti, Matteo and Dachwald, Bernd and Macdonald, Malcolm and McInnes, Colin and Seboldt, Wolfgang and Quantius, Dominik and Bauer, Waldemar and Wiedemann, Carsten and Grimm, Christian D. and Hercik, David and Ho, Tra-Mi and Lange, Caroline and Schmitz, Nicole}, title = {Paths not taken - The Gossamer roadmap's other options}, series = {Advances in Space Research}, volume = {67}, journal = {Advances in Space Research}, number = {9}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0273-1177}, doi = {10.1016/j.asr.2021.01.044}, pages = {2912 -- 2956}, year = {2021}, language = {en} } @article{AkimbekovDigelAbdievaetal.2021, author = {Akimbekov, Nuraly S. and Digel, Ilya and Abdieva, Gulzhamal and Ualieva, Perizat and Tastambek, Kuanysh}, title = {Lignite biosolubilization and bioconversion by Bacillus sp.: the collation of analytical data}, series = {Biofuels}, volume = {12}, journal = {Biofuels}, number = {3}, publisher = {Taylor \& Francis}, address = {London}, issn = {1759-7277}, pages = {247 -- 258}, year = {2021}, abstract = {The vast metabolic potential of microbes in brown coal (lignite) processing and utilization can greatly contribute to innovative approaches to sustainable production of high-value products from coal. In this study, the multi-faceted and complex coal biosolubilization process by Bacillus sp. RKB 7 isolate from the Kazakhstan coal-mining soil is reported, and the derived products are characterized. Lignite solubilization tests performed for surface and suspension cultures testify to the formation of numerous soluble lignite-derived substances. Almost 24\% of crude lignite (5\% w/v) was solubilized within 14 days under slightly alkaline conditions (pH 8.2). FTIR analysis revealed various functional groups in the obtained biosolubilization products. Analyses of the lignite-derived humic products by UV-Vis and fluorescence spectrometry as well as elemental analysis yielded compatible results indicating the emerging products had a lower molecular weight and degree of aromaticity. Furthermore, XRD and SEM analyses were used to evaluate the biosolubilization processes from mineralogical and microscopic points of view. The findings not only contribute to a deeper understanding of microbe-mineral interactions in coal environments, but also contribute to knowledge of coal biosolubilization and bioconversion with regard to sustainable production of humic substances. The detailed and comprehensive analyses demonstrate the huge biotechnological potential of Bacillus sp. for agricultural productivity and environmental health.}, language = {en} } @article{HeiligersSchoutetensDachwald2021, author = {Heiligers, Jeannette and Schoutetens, Frederic and Dachwald, Bernd}, title = {Photon-sail equilibria in the alpha centauri system}, series = {Journal of Guidance, Control, and Dynamics}, volume = {44}, journal = {Journal of Guidance, Control, and Dynamics}, number = {5}, issn = {1533-3884}, doi = {10.2514/1.G005446}, pages = {1053 -- 1061}, year = {2021}, language = {en} } @article{Bung2021, author = {Bung, Daniel Bernhard}, title = {Extreme flooding in Western Germany: some thoughts on hazards, return periods and risk}, series = {Hydrolink}, journal = {Hydrolink}, number = {4}, publisher = {International Association for Hydro-Environment Engineering and Research (IAHR)}, address = {Madrid}, pages = {108 -- 113}, year = {2021}, abstract = {The low-pressure system Bernd involved extreme rainfalls in the Western part of Germany in July 2021, resulting in major floods, severe damages and a tremendous number of casualties. Such extreme events are rare and full flood protection can never be ensured with reasonable financial means. But still, this event must be starting point to reconsider current design concepts. This article aims at sharing some thoughts on potential hazards, the selection of return periods and remaining risk with the focus on Germany.}, language = {en} } @article{Golland2021, author = {Golland, Alexander}, title = {Cookies \& Co. - trotz neuem Gesetz alte Probleme f{\"u}r Website-Betreiber. Anpassung des deutschen Rechts durch das TTDSG an unionsrechtliche Vorgaben zum 1.12.2021}, series = {NWB Steuer- und Wirtschaftsrecht}, volume = {2021}, journal = {NWB Steuer- und Wirtschaftsrecht}, number = {25}, publisher = {NWB-Verlag}, address = {Herne}, issn = {0028-3460}, pages = {1818 -- 1825}, year = {2021}, language = {de} } @article{Golland2021, author = {Golland, Alexander}, title = {Neuregelungen zum Datenschutz: Ein Update f{\"u}r Website-Betreiber. Reform des Telekommunikations- und Telemedienrechts verabschiedet}, series = {NWB Rechnungswesen - BBK}, journal = {NWB Rechnungswesen - BBK}, number = {14}, isbn = {0340-9848}, pages = {672 -- 674}, year = {2021}, language = {de} } @article{GoettenHavermannBraunetal.2021, author = {G{\"o}tten, Falk and Havermann, Marc and Braun, Carsten and Marino, Matthew and Bil, Cees}, title = {Aerodynamic Investigations of UAV Sensor Turrets - A Combined Wind-tunnel and CFD Approach}, series = {SciTech 2021, AIAA SciTech Forum, online, WW, Jan 11-15, 2021}, journal = {SciTech 2021, AIAA SciTech Forum, online, WW, Jan 11-15, 2021}, publisher = {AIAA}, address = {Reston, Va.}, doi = {10.2514/6.2021-1535}, pages = {1 -- 12}, year = {2021}, language = {en} } @article{HunkerGossmannRamanetal.2021, author = {Hunker, Jan L. and Gossmann, Matthias and Raman, Aravind Hariharan and Linder, Peter}, title = {Artificial neural networks in cardiac safety assessment: Classification of chemotherapeutic compound effects on hiPSC-derived cardiomyocyte contractility}, series = {Journal of Pharmacological and Toxicological Methods}, volume = {111}, journal = {Journal of Pharmacological and Toxicological Methods}, number = {Article number 107044}, publisher = {Elsevier}, address = {New York}, issn = {1056-8719}, doi = {10.1016/j.vascn.2021.107044}, year = {2021}, language = {en} } @article{Golland2021, author = {Golland, Alexander}, title = {Bußgelder wegen Datenschutzverst{\"o}ßen - Vermeidung und Verteidigung. Deutsche Aufsichtsbeh{\"o}rden setzen seit vergangenem Jahr zunehmend auf Sanktion}, series = {NWB Steuer- und Wirtschaftsrecht}, volume = {36}, journal = {NWB Steuer- und Wirtschaftsrecht}, publisher = {NWB-Verlag}, address = {Herne}, isbn = {0028-3460}, pages = {2678 -- 2687}, year = {2021}, language = {de} } @article{ErpicumCrookstonBombardellietal.2021, author = {Erpicum, Sebastien and Crookston, Brian M. and Bombardelli, Fabian and Bung, Daniel Bernhard and Felder, Stefan and Mulligan, Sean and Oertel, Mario and Palermo, Michele}, title = {Hydraulic structures engineering: An evolving science in a changing world}, series = {Wires Water}, volume = {8}, journal = {Wires Water}, number = {2}, publisher = {Wiley}, address = {Weinheim}, issn = {2049-1948}, doi = {10.1002/wat2.1505}, year = {2021}, language = {en} } @article{ButenwegBursiPaolaccietal.2021, author = {Butenweg, Christoph and Bursi, Oreste S. and Paolacci, Fabrizio and Marinković, Marko and Lanese, Igor and Nardin, Chiara and Quinci, Gianluca}, title = {Seismic performance of an industrial multi-storey frame structure with process equipment subjected to shake table testing}, series = {Engineering Structures}, volume = {243}, journal = {Engineering Structures}, number = {15}, editor = {Yang, J.}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0141-0296}, doi = {10.1016/j.engstruct.2021.112681}, year = {2021}, abstract = {Past earthquakes demonstrated the high vulnerability of industrial facilities equipped with complex process technologies leading to serious damage of process equipment and multiple and simultaneous release of hazardous substances. Nonetheless, current standards for seismic design of industrial facilities are considered inadequate to guarantee proper safety conditions against exceptional events entailing loss of containment and related consequences. On these premises, the SPIF project -Seismic Performance of Multi-Component Systems in Special Risk Industrial Facilities- was proposed within the framework of the European H2020 SERA funding scheme. In detail, the objective of the SPIF project is the investigation of the seismic behaviour of a representative industrial multi-storey frame structure equipped with complex process components by means of shaking table tests. Along this main vein and in a performance-based design perspective, the issues investigated in depth are the interaction between a primary moment resisting frame (MRF) steel structure and secondary process components that influence the performance of the whole system; and a proper check of floor spectra predictions. The evaluation of experimental data clearly shows a favourable performance of the MRF structure, some weaknesses of local details due to the interaction between floor crossbeams and process components and, finally, the overconservatism of current design standards w.r.t. floor spectra predictions.}, language = {en} } @article{HacklNacovKammerlohretal.2021, author = {Hackl, Michael and Nacov, Julia and Kammerlohr, Sandra and Staat, Manfred and Buess, Eduard and Leschinger, Tim and M{\"u}ller, Lars P. and Wegmann, Kilian}, title = {Intratendinous Strain Variations of the Supraspinatus Tendon Depending on Repair Technique: A Biomechanical Analysis Regarding the Cause of Medial Cuff Failure}, series = {The American Journal of Sports Medicine}, volume = {49}, journal = {The American Journal of Sports Medicine}, number = {7}, publisher = {Sage}, address = {London}, issn = {1552-3365}, doi = {10.1177/03635465211006138}, pages = {1847 -- 1853}, year = {2021}, language = {en} } @article{TranStaat2021, author = {Tran, Ngoc Trinh and Staat, Manfred}, title = {Direct plastic structural design under random strength and random load by chance constrained programming}, series = {European Journal of Mechanics - A/Solids}, volume = {85}, journal = {European Journal of Mechanics - A/Solids}, number = {Article 104106}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0997-7538}, doi = {10.1016/j.euromechsol.2020.104106}, year = {2021}, language = {en} } @article{BlankeRegerDoeringetal.2021, author = {Blanke, Tobias and Reger, Vitali and D{\"o}ring, Bernd and G{\"o}ttsche, Joachim and Kuhnhenne, Markus}, title = {Koaxiale Stahlenergiepf{\"a}hle}, series = {Stahlbau}, volume = {90. 2021}, journal = {Stahlbau}, number = {6}, publisher = {Wiley}, address = {Weinheim}, pages = {417 -- 424}, year = {2021}, abstract = {Ein entscheidender Teil der Energiewende ist die W{\"a}rmewende im Geb{\"a}udesektor. Ein Schl{\"u}sselelement sind hier W{\"a}rmepumpen. Diese ben{\"o}tigen eine W{\"a}rmequelle, der sie Energie entziehen k{\"o}nnen, um sie auf ein h{\"o}heres Temperaturniveau zu transformieren. Diese W{\"a}rmequelle kann bspw. das Erdreich sein, dessen W{\"a}rme durch Erdsonden erschlossen werden kann. In diesem Beitrag werden in Stahlpf{\"a}hle integrierte Koaxialsonden mit dem Stand der Technik von Erdsonden gleichen Durchmessers bez{\"u}glich ihrer thermischen Leistungsmerkmale verglichen. Die Stahlenergiepf{\"a}hle bieten neben der W{\"a}rmegewinnung weitere Vorteile, da sie auch eine statische Funktion {\"u}bernehmen und r{\"u}ckstandsfrei zur{\"u}ckgebaut werden k{\"o}nnen. Es werden analytische und numerische Berechnungen vorgestellt, um die thermischen Potenziale beider Systeme zu vergleichen. Außerdem wird ein Testaufbau gezeigt, bei dem Stahlenergiepf{\"a}hle in zwei verschiedenen L{\"a}ngen mit vorhandenen g{\"a}ngigen Erdsonden verglichen werden k{\"o}nnen. Die Berechnungen zeigen einen deutlichen thermischen Mehrertrag zwischen 26 \% und 148 \% der Stahlenergiepf{\"a}hle gegen{\"u}ber dem Stand der Technik abh{\"a}ngig vom Erdreich. Die Messergebnisse zeigen einen thermischen Mehrertrag von {\"u}ber 100 \%. Es l{\"a}sst sich also signifikante Erdsondenl{\"a}nge einsparen. Dabei ist zu beachten, dass sich damit der thermisch genutzte Bereich des Erdreichs reduziert, wodurch die thermische Regeneration und/oder das Langzeitverhalten des Erdreichs an Bedeutung gewinnt.}, language = {de} } @article{FaganBitzBjoerkmanBurtscheretal.2021, author = {Fagan, Andrew J. and Bitz, Andreas and Bj{\"o}rkman-Burtscher, Isabella M. and Collins, Christopher M. and Kimbrell, Vera and Raaijmakers, Alexander J. E.}, title = {7T MR Safety}, series = {Journal of Magnetic Resonance Imaging (JMRI)}, volume = {53}, journal = {Journal of Magnetic Resonance Imaging (JMRI)}, number = {2}, publisher = {Wiley}, address = {Weinheim}, issn = {1522-2586}, doi = {10.1002/jmri.27319}, pages = {333 -- 346}, year = {2021}, language = {en} } @article{MeyerGranrathFeyerletal.2021, author = {Meyer, Max-Arno and Granrath, Christian and Feyerl, G{\"u}nter and Richenhagen, Johannes and Kaths, Jakob and Andert, Jakob}, title = {Closed-loop platoon simulation with cooperative intelligent transportation systems based on vehicle-to-X communication}, series = {Simulation Modelling Practice and Theory}, volume = {106}, journal = {Simulation Modelling Practice and Theory}, number = {Art. 102173}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1569-190X}, doi = {10.1016/j.simpat.2020.102173}, year = {2021}, language = {en} } @article{SerrorHackHenzeetal.2021, author = {Serror, Martin and Hack, Sacha and Henze, Martin and Schuba, Marko and Wehrle, Klaus}, title = {Challenges and Opportunities in Securing the Industrial Internet of Things}, series = {IEEE Transactions on Industrial Informatics}, volume = {17}, journal = {IEEE Transactions on Industrial Informatics}, number = {5}, publisher = {IEEE}, address = {New York}, issn = {1941-0050}, doi = {10.1109/TII.2020.3023507}, pages = {2985 -- 2996}, year = {2021}, language = {en} } @article{BerneckerBoyerGathmann2021, author = {Bernecker, Andreas and Boyer, Pierre C. and Gathmann, Christina}, title = {The Role of Electoral Incentives for Policy Innovation: Evidence from the US Welfare Reform}, series = {American Economic Journal: Economic Policy}, volume = {13}, journal = {American Economic Journal: Economic Policy}, number = {2}, publisher = {American Economic Association}, address = {Nashville, Tenn.}, issn = {1945-774X}, doi = {10.1257/pol.20190690}, pages = {26 -- 57}, year = {2021}, language = {en} } @article{TranEbeling2021, author = {Tran, Duc Hung and Ebeling, Felix}, title = {Die risikoad{\"a}quate Bestimmung von Eigenkapitalkosten bei konzerninternen Routinefunktionen}, series = {Der Betrieb}, volume = {74}, journal = {Der Betrieb}, number = {29}, issn = {0005-9935}, pages = {1553 -- 1560}, year = {2021}, abstract = {Eigenkapitalkosten sind eine wesentliche Determinante bei der Wertbestimmung von Unternehmen und Unternehmensteilen. Die Eigenkapitalkosten werden regelm{\"a}ßig mittels des CAPM bestimmt. F{\"u}r sog. konzerninterne Routinefunktionen mit geringem Risiko stellt diese Bestimmung mittels CAPM ein Problem dar, da b{\"o}rsennotierte Peergroups f{\"u}r eine zuverl{\"a}ssige Bestimmung des Beta-Faktors meist nicht identifizierbar sind. Damit ergeben sich bei Bewertungen von Routineunternehmen Unsicherheiten und Konfliktpotenzial in steuerlichen Betriebspr{\"u}fungen. Dieser Beitrag gibt einen {\"U}berblick der in der Praxis genutzten Ans{\"a}tze und stellt eine theoretische Fundierung zur Bestimmung der Eigenkapitalkosten von konzerninternen Routinefunktionen vor. Dabei wird verdeutlicht, dass Eigenkapitalkosten von konzerninternen Routinefunktionen nicht denen des Gesamtkonzerns entsprechen und Praktikerans{\"a}tze eine grunds{\"a}tzliche Berechtigung besitzen.}, language = {de} } @article{HugenrothBorchardtRitteretal.2021, author = {Hugenroth, Kristin and Borchardt, Ralf and Ritter, Philine and Groß‑Hardt, Sascha and Meyns, Bart and Verbelen, Tom and Steinseifer, Ulrich and Kaufmann, Tim A. S. and Engelmann, Ulrich M.}, title = {Optimizing cerebral perfusion and hemodynamics during cardiopulmonary bypass through cannula design combining in silico, in vitro and in vivo input}, series = {Scientific Reports}, volume = {11}, journal = {Scientific Reports}, number = {Art. No. 16800}, publisher = {Springer}, address = {Berlin}, issn = {2045-2322}, doi = {10.1038/s41598-021-96397-2}, pages = {1 -- 12}, year = {2021}, abstract = {Cardiopulmonary bypass (CPB) is a standard technique for cardiac surgery, but comes with the risk of severe neurological complications (e.g. stroke) caused by embolisms and/or reduced cerebral perfusion. We report on an aortic cannula prototype design (optiCAN) with helical outflow and jet-splitting dispersion tip that could reduce the risk of embolic events and restores cerebral perfusion to 97.5\% of physiological flow during CPB in vivo, whereas a commercial curved-tip cannula yields 74.6\%. In further in vitro comparison, pressure loss and hemolysis parameters of optiCAN remain unaffected. Results are reproducibly confirmed in silico for an exemplary human aortic anatomy via computational fluid dynamics (CFD) simulations. Based on CFD simulations, we firstly show that optiCAN design improves aortic root washout, which reduces the risk of thromboembolism. Secondly, we identify regions of the aortic intima with increased risk of plaque release by correlating areas of enhanced plaque growth and high wall shear stresses (WSS). From this we propose another easy-to-manufacture cannula design (opti2CAN) that decreases areas burdened by high WSS, while preserving physiological cerebral flow and favorable hemodynamics. With this novel cannula design, we propose a cannulation option to reduce neurological complications and the prevalence of stroke in high-risk patients after CPB.}, language = {en} } @article{BrockhausBehbahaniMurisetal.2021, author = {Brockhaus, Moritz K. and Behbahani, Mehdi and Muris, Farina and Jansen, Sebastian V. and Schmitz- Rode, Thomas and Steinseifer, Ulrich and Clauser, Johanna C.}, title = {In vitro thrombogenicity testing of pulsatile mechanical circulatory support systems: Design and proof-of-concept}, series = {Artificial Organs}, volume = {45}, journal = {Artificial Organs}, number = {12}, publisher = {Wiley}, address = {Weinheim}, issn = {1525-1594}, doi = {10.1111/aor.14046}, pages = {1513 -- 1521}, year = {2021}, abstract = {Thrombogenic complications are a main issue in mechanical circulatory support (MCS). There is no validated in vitro method available to quantitatively assess the thrombogenic performance of pulsatile MCS devices under realistic hemodynamic conditions. The aim of this study is to propose a method to evaluate the thrombogenic potential of new designs without the use of complex in-vivo trials. This study presents a novel in vitro method for reproducible thrombogenicity testing of pulsatile MCS systems using low molecular weight heparinized porcine blood. Blood parameters are continuously measured with full blood thromboelastometry (ROTEM; EXTEM, FIBTEM and a custom-made analysis HEPNATEM). Thrombus formation is optically observed after four hours of testing. The results of three experiments are presented each with two parallel loops. The area of thrombus formation inside the MCS device was reproducible. The implantation of a filter inside the loop catches embolizing thrombi without a measurable increase of platelet activation, allowing conclusions of the place of origin of thrombi inside the device. EXTEM and FIBTEM parameters such as clotting velocity (α) and maximum clot firmness (MCF) show a total decrease by around 6\% with a characteristic kink after 180 minutes. HEPNATEM α and MCF rise within the first 180 minutes indicate a continuously increasing activation level of coagulation. After 180 minutes, the consumption of clotting factors prevails, resulting in a decrease of α and MCF. With the designed mock loop and the presented protocol we are able to identify thrombogenic hot spots inside a pulsatile pump and characterize their thrombogenic potential.}, language = {en} } @article{LeiseEsserEichenlaubetal.2021, author = {Leise, Philipp and Eßer, Arved and Eichenlaub, Tobias and Schleiffer, Jean-Eric and Altherr, Lena and Rinderknecht, Stephan and Pelz, Peter F.}, title = {Sustainable system design of electric powertrains - comparison of optimization methods}, series = {Engineering Optimization}, journal = {Engineering Optimization}, publisher = {Taylor \& Francis}, address = {London}, issn = {0305-215X}, doi = {10.1080/0305215X.2021.1928660}, year = {2021}, abstract = {The transition within transportation towards battery electric vehicles can lead to a more sustainable future. To account for the development goal 'climate action' stated by the United Nations, it is mandatory, within the conceptual design phase, to derive energy-efficient system designs. One barrier is the uncertainty of the driving behaviour within the usage phase. This uncertainty is often addressed by using a stochastic synthesis process to derive representative driving cycles and by using cycle-based optimization. To deal with this uncertainty, a new approach based on a stochastic optimization program is presented. This leads to an optimization model that is solved with an exact solver. It is compared to a system design approach based on driving cycles and a genetic algorithm solver. Both approaches are applied to find efficient electric powertrains with fixed-speed and multi-speed transmissions. Hence, the similarities, differences and respective advantages of each optimization procedure are discussed.}, language = {en} } @article{GrundlachBaumannEngelmann2021, author = {Grundlach, Michael and Baumann, Martin and Engelmann, Ulrich M.}, title = {How Multimodal Examinations Can Increase Sustainable Student Gain by Aligning Teaching and Assessment}, series = {Current Directions in Biomedical Engineering}, volume = {7}, journal = {Current Directions in Biomedical Engineering}, number = {7/2}, editor = {D{\"o}ssel, Olaf}, publisher = {De Gruyter}, address = {Berlin}, isbn = {2364-5504}, doi = {10.1515/cdbme-2021-2019}, pages = {73 -- 76}, year = {2021}, abstract = {Modern industry and multi-discipline projects require highly trained individuals with resilient science and engineering back-grounds. Graduates must be able to agilely apply excellent theoretical knowledge in their subject matter as well as essential practical "hands-on" knowledge of diverse working processes to solve complex problems. To meet these demands, university education follows the concept of Constructive Alignment and thus increasingly adopts the teaching of necessary practical skills to the actual industry requirements and assessment routines. However, a systematic approach to coherently align these three central teaching demands is strangely absent from current university curricula. We demonstrate the feasibility of implementing practical assessments in a regular theory-based examination, thus defining the term "blended assessment". We assessed a course for natural science and engineering students pursuing a career in biomedical engineering, and evaluated the benefit of blended assessment exams for students and lecturers. Our controlled study assessed the physiological background of electrocardiograms (ECGs), the practical measurement of ECG curves, and their interpretation of basic pathologic alterations. To study on long time effects, students have been assessed on the topic twice with a time lag of 6 months. Our findings suggest a significant improvement in student gain with respect to practical skills and theoretical knowledge. The results of the reassessments support these outcomes. From the lecturers' point of view, blended assessment complements practical training courses while keeping organizational effort manageable. We consider blended assessment a viable tool for providing an improved student gain, industry-ready education format that should be evaluated and established further to prepare university graduates optimally for their future careers.}, language = {en} } @article{Olbertz2021, author = {Olbertz, Klaus}, title = {Die Dienstreisezeit als Arbeitszeit - oder doch nicht? : Zur arbeitgeberfreundlichen Bewertung von Dienstreisezeiten durch das Bundesarbeitsgericht}, series = {NWB - Steuer- und Wirtschaftsrecht}, journal = {NWB - Steuer- und Wirtschaftsrecht}, number = {1}, issn = {0028-3460}, pages = {38 -- 44}, year = {2021}, abstract = {Der arbeitsrechtlich richtige Umgang mit Zeiten einer Dienstreise kann in der betrieblichen Praxis Probleme bereiten. Ob die Reisezeiten als solche Arbeitszeit i. S. des Arbeitszeitgesetzes (ArbZG ) darstellen, also bspw. auf die t{\"a}gliche H{\"o}chstarbeitszeit angerechnet werden m{\"u}ssen oder nicht, ist oftmals genauso unklar wie die Frage, ob und inwieweit Reisezeiten verg{\"u}tungspflichtig sind. Aber auch, ob ein Arbeitnehmer {\"u}berhaupt zur Durchf{\"u}hrung einer Dienstreise verpflichtet werden kann, ist ein m{\"o}glicher Anlass von Streitigkeiten zwischen den Arbeitsvertragsparteien, wie verschiedene Gerichtsentscheidungen zeigen. Der nachfolgende Beitrag beantwortet die aufgeworfenen Fragen und gibt hierzu einen praxisorientierten {\"U}berblick.}, language = {de} } @article{HeinkeKnickerAlbracht2021, author = {Heinke, Lars N. and Knicker, Axel J. and Albracht, Kirsten}, title = {Test-retest reliability of the internal shoulder rotator muscles' stretch reflex in healthy men}, series = {Journal of Electromyography and Kinesiology}, volume = {62}, journal = {Journal of Electromyography and Kinesiology}, number = {Article 102611}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1050-6411}, doi = {10.1016/j.jelekin.2021.102611}, year = {2021}, abstract = {Until now the reproducibility of the short latency stretch reflex of the internal rotator muscles of the glenohumeral joint has not been identified. Twenty-three healthy male participants performed three sets of external shoulder rotation stretches with various pre-activation levels on two different dates of measurement to assess test-retest reliability. All stretches were applied with a dynamometer acceleration of 104°/s2 and a velocity of 150°/s. Electromyographical response was measured via surface EMG. Reflex latencies showed a pre-activation effect (ƞ2 = 0,355). ICC ranged from 0,735 to 0,909 indicating an overall "good" relative reliability. SRD 95\% lay between ±7,0 to ±12,3 ms.. The reflex gain showed overall poor test-retest reproducibility. The chosen methodological approach presented a suitable test protocol for shoulder muscles stretch reflex latency evaluation. A proof-of-concept study to validate the presented methodical approach in shoulder involvement including subjects with clinically relevant conditions is recommended.}, language = {en} } @article{Timme2021, author = {Timme, Michael}, title = {Rechtsprechungs{\"u}bersicht zum Wohnraummietrecht}, series = {Monatsschrift f{\"u}r Deutsches Recht}, volume = {75}, journal = {Monatsschrift f{\"u}r Deutsches Recht}, number = {1}, publisher = {Verlag Dr. Otto Schmidt}, address = {K{\"o}ln}, issn = {2194-4202}, doi = {10.9785/mdtr-2021-750113}, pages = {6 -- 11}, year = {2021}, language = {de} } @article{ZabirovSchleserBucherer2021, author = {Zabirov, Alexander and Schleser, Markus and Bucherer, Sebastian}, title = {F{\"u}ge- und Dichtkonzept f{\"u}r einen Leichtbauverbrennungsmotor}, series = {adh{\"a}sion KLEBEN \& DICHTEN}, volume = {65}, journal = {adh{\"a}sion KLEBEN \& DICHTEN}, number = {11}, publisher = {Springer Nature}, address = {Cham}, issn = {2192-8681}, doi = {10.1007/s35145-021-0531-5}, pages = {12 -- 19}, year = {2021}, language = {de} } @article{Olbertz2021, author = {Olbertz, Klaus}, title = {Wichtige arbeitsrechtliche Entwicklungen im Jahr 2020 : Der Jahresr{\"u}ckblick auf alles Wissenswerte im Arbeitsrecht des vergangenen Jahres}, series = {NWB - Steuer- und Wirtschaftsrecht}, journal = {NWB - Steuer- und Wirtschaftsrecht}, number = {10}, issn = {0028-3460}, pages = {703 -- 715}, year = {2021}, abstract = {Im Anschluss an die arbeitsrechtlichen Jahres{\"u}bersichten der vergangenen Jahre (NWB 5/2019 S. 266; NWB 8/2020 S. 557) gibt der nachfolgende Beitrag einen {\"U}berblick {\"u}ber relevante Entwicklungen im Arbeitsrecht des Jahres 2020. Der erste Teil besch{\"a}ftigt sich hierbei mit gesetzlichen {\"A}nderungen. Neben Regelungen, die auf die COVID-19-Pandemie zur{\"u}ckgef{\"u}hrt werden k{\"o}nnen, hat der Gesetzgeber auch andere Vorhaben umgesetzt. So wurde u. a. das Arbeitnehmerentsenderecht reformiert. F{\"u}r Diskussionen sorgt(e) zudem das Gesetzesvorhaben zur Regelung mobiler Arbeit. Im zweiten Teil werden f{\"u}r die Praxis wichtige h{\"o}chstrichterliche Gerichtsentscheidungen zum Arbeitsrecht erl{\"a}utert, alphabetisch sortiert von A (wie Antidiskriminierungsrecht) bis U (wie Urlaub).}, language = {de} } @article{Olbertz2021, author = {Olbertz, Klaus}, title = {Die Flexibilisierung von Arbeitszeit durch den Abruf von Arbeit : M{\"o}glichkeiten und Grenzen arbeitsvertraglicher Gestaltung zur Vermeidung von „Leerlaufzeiten"}, series = {NWB - Steuer- und Wirtschaftsrecht}, journal = {NWB - Steuer- und Wirtschaftsrecht}, number = {15}, issn = {0028-3460}, pages = {1055 -- 1063}, year = {2021}, abstract = {Die Arbeitswelt ist im Umbruch. Der Bedarf an flexiblen Arbeitszeitmodellen nimmt stetig zu, wobei die Corona-Pandemie dieses Bed{\"u}rfnis nochmals versch{\"a}rft hat. Gerade auch in kleineren und mittleren Unternehmen w{\"a}chst die Notwendigkeit, den Einsatz der Besch{\"a}ftigten m{\"o}glichst bedarfsgerecht zu steuern, also bei guter Auftragslage mehr Arbeitszeit abzurufen und bei ausbleibenden Auftr{\"a}gen die Arbeitszeit zu reduzieren und somit bezahlte „Leerlaufzeiten" zu vermeiden. Der Gesetzgeber stellt den Arbeitgebern hierf{\"u}r das Instrument der sog. Abrufarbeit ( \S 12 Teilzeit- und Befristungsgesetz - TzBfG ) zur Verf{\"u}gung. In dem nachfolgenden Beitrag werden M{\"o}glichkeiten und Grenzen der Abrufarbeit skizziert und konkrete arbeitsvertragliche Gestaltungsm{\"o}glichkeiten aufgezeigt.}, language = {de} } @article{Olbertz2021, author = {Olbertz, Klaus}, title = {Vertragsgestaltungen bei der Besch{\"a}ftigung von Rentnern in Unternehmen : (Befristete) Besch{\"a}ftigungsverh{\"a}ltnisse als sinnvolles Instrument zum Schließen von Personall{\"u}cken}, series = {NWB - Steuer- und Wirtschaftsrecht}, journal = {NWB - Steuer- und Wirtschaftsrecht}, number = {25}, issn = {0028-3460}, pages = {1810 -- 1817}, year = {2021}, language = {de} } @article{BraunChengDoweyetal.2021, author = {Braun, Sebastian and Cheng, Chi-Tsun and Dowey, Steve and Wollert, J{\"o}rg}, title = {Performance evaluation of skill-based order-assignment in production environments with multi-agent systems}, series = {IEEE Journal of Emerging and Selected Topics in Industrial Electronics}, journal = {IEEE Journal of Emerging and Selected Topics in Industrial Electronics}, number = {Early Access}, publisher = {IEEE}, address = {New York}, issn = {2687-9735}, doi = {10.1109/JESTIE.2021.3108524}, year = {2021}, abstract = {The fourth industrial revolution introduces disruptive technologies to production environments. One of these technologies are multi-agent systems (MASs), where agents virtualize machines. However, the agent's actual performances in production environments can hardly be estimated as most research has been focusing on isolated projects and specific scenarios. We address this gap by implementing a highly connected and configurable reference model with quantifiable key performance indicators (KPIs) for production scheduling and routing in single-piece workflows. Furthermore, we propose an algorithm to optimize the search of extrema in highly connected distributed systems. The benefits, limits, and drawbacks of MASs and their performances are evaluated extensively by event-based simulations against the introduced model, which acts as a benchmark. Even though the performance of the proposed MAS is, on average, slightly lower than the reference system, the increased flexibility allows it to find new solutions and deliver improved factory-planning outcomes. Our MAS shows an emerging behavior by using flexible production techniques to correct errors and compensate for bottlenecks. This increased flexibility offers substantial improvement potential. The general model in this paper allows the transfer of the results to estimate real systems or other models.}, language = {en} } @article{MolinnusDrinicIkenetal.2021, author = {Molinnus, Denise and Drinic, Aleksander and Iken, Heiko and Kr{\"o}ger, Nadja and Zinser, Max and Smeets, Ralf and K{\"o}pf, Marius and Kopp, Alexander and Sch{\"o}ning, Michael Josef}, title = {Towards a flexible electrochemical biosensor fabricated from biocompatible Bombyx mori silk}, series = {Biosensors and Bioelectronics}, volume = {183}, journal = {Biosensors and Bioelectronics}, number = {Art. 113204}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0956-5663}, doi = {10.1016/j.bios.2021.113204}, year = {2021}, language = {en} } @article{Fissabre2021, author = {Fissabre, Anke}, title = {Ein pazifistisches Kriegerdenkmal der Moderne. Das Totenkreuz von Rudolf Schwarz}, series = {In situ: Zeitschrift f{\"u}r Architekturgeschichte}, journal = {In situ: Zeitschrift f{\"u}r Architekturgeschichte}, number = {1}, publisher = {Wernersche Verlagsgesellschaft}, address = {Worms}, issn = {1866-959X}, pages = {127 -- 138}, year = {2021}, language = {de} } @article{HennesLaumann2021, author = {Hennes, Philipp and Laumann, J{\"o}rg}, title = {Ansatz der Drehbehinderung aus Koppelpfetten mit d{\"u}nnwandigen kaltgeformten Z-Profilen}, series = {Stahlbau}, volume = {90}, journal = {Stahlbau}, number = {3}, publisher = {Ernst \& Sohn}, address = {Berlin}, issn = {1437-1049}, doi = {10.1002/stab.202000104}, pages = {158 -- 168}, year = {2021}, language = {de} } @article{YoshinobuSchoening2021, author = {Yoshinobu, Tatsuo and Sch{\"o}ning, Michael Josef}, title = {Light-addressable potentiometric sensors (LAPS) for cell monitoring and biosensing}, series = {Current Opinion in Electrochemistry}, journal = {Current Opinion in Electrochemistry}, number = {In Press, Journal Pre-proof}, publisher = {Elsevier}, address = {Amsterdam}, issn = {2451-9103}, doi = {10.1016/j.coelec.2021.100727}, year = {2021}, language = {en} } @article{Maurischat2021, author = {Maurischat, Andreas}, title = {Algebraic independence of the Carlitz period and its hyperderivatives}, pages = {1 -- 12}, year = {2021}, language = {en} } @article{WertIkenSchoeningetal.2021, author = {Wert, Stefan and Iken, Heiko and Sch{\"o}ning, Michael Josef and Matysik, Frank-Michael}, title = {Development of a temperature-pulse enhanced electrochemical glucose biosensor and characterization of its stability via scanning electrochemical microscopy}, series = {Electroanalysis}, journal = {Electroanalysis}, number = {Early View}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1521-4109}, doi = {10.1002/elan.202100089}, year = {2021}, abstract = {Glucose oxidase (GOx) is an enzyme frequently used in glucose biosensors. As increased temperatures can enhance the performance of electrochemical sensors, we investigated the impact of temperature pulses on GOx that was drop-coated on flattened Pt microwires. The wires were heated by an alternating current. The sensitivity towards glucose and the temperature stability of GOx was investigated by amperometry. An up to 22-fold increase of sensitivity was observed. Spatially resolved enzyme activity changes were investigated via scanning electrochemical microscopy. The application of short (<100 ms) heat pulses was associated with less thermal inactivation of the immobilized GOx than long-term heating.}, language = {en} } @article{LowisFergusonPaulssenetal.2021, author = {Lowis, Carsten and Ferguson, Simon and Paulßen, Elisabeth and Hoehr, Cornelia}, title = {Improved Sc-44 production in a siphon-style liquid target on a medical cyclotron}, series = {Applied Radiation and Isotopes}, volume = {172}, journal = {Applied Radiation and Isotopes}, number = {Art. 109675}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0969-8043}, doi = {10.1016/j.apradiso.2021.109675}, year = {2021}, language = {en} } @article{WaldvogelRitzmannFreyleretal.2021, author = {Waldvogel, Janice and Ritzmann, Ramona and Freyler, Kathrin and Helm, Michael and Monti, Elena and Albracht, Kirsten and St{\"a}udle, Benjamin and Gollhofer, Albert and Narici, Marco}, title = {The Anticipation of Gravity in Human Ballistic Movement}, series = {Frontiers in Physiology}, journal = {Frontiers in Physiology}, publisher = {Frontiers}, address = {Lausanne}, issn = {1664-042X}, doi = {10.3389/fphys.2021.614060}, year = {2021}, abstract = {Stretch-shortening type actions are characterized by lengthening of the pre-activated muscle-tendon unit (MTU) in the eccentric phase immediately followed by muscle shortening. Under 1 g, pre-activity before and muscle activity after ground contact, scale muscle stiffness, which is crucial for the recoil properties of the MTU in the subsequent push-off. This study aimed to examine the neuro-mechanical coupling of the stretch-shortening cycle in response to gravity levels ranging from 0.1 to 2 g. During parabolic flights, 17 subjects performed drop jumps while electromyography (EMG) of the lower limb muscles was combined with ultrasound images of the gastrocnemius medialis, 2D kinematics and kinetics to depict changes in energy management and performance. Neuro-mechanical coupling in 1 g was characterized by high magnitudes of pre-activity and eccentric muscle activity allowing an isometric muscle behavior during ground contact. EMG during pre-activity and the concentric phase systematically increased from 0.1 to 1 g. Below 1 g the EMG in the eccentric phase was diminished, leading to muscle lengthening and reduced MTU stretches. Kinetic energy at take-off and performance were decreased compared to 1 g. Above 1 g, reduced EMG in the eccentric phase was accompanied by large MTU and muscle stretch, increased joint flexion amplitudes, energy loss and reduced performance. The energy outcome function established by linear mixed model reveals that the central nervous system regulates the extensor muscles phase- and load-specifically. In conclusion, neuro-mechanical coupling appears to be optimized in 1 g. Below 1 g, the energy outcome is compromised by reduced muscle stiffness. Above 1 g, loading progressively induces muscle lengthening, thus facilitating energy dissipation.}, language = {en} } @article{BohndickBosseJaenschetal.2021, author = {Bohndick, Carla and Bosse, Elke and J{\"a}nsch, Vanessa K. and Barnat, Miriam}, title = {How different diversity factors affect the perception of first-year requirements in higher education}, series = {Frontline Learning Research}, volume = {9}, journal = {Frontline Learning Research}, number = {2}, publisher = {EARLI}, issn = {2295-3159}, doi = {10.14786/flr.v9i2.667}, pages = {78 -- 95}, year = {2021}, abstract = {In the light of growing university entry rates, higher education institutions not only serve larger numbers of students, but also seek to meet first-year students' ever more diverse needs. Yet to inform universities how to support the transition to higher education, research only offers limited insights. Current studies tend to either focus on the individual factors that affect student success or they highlight students' social background and their educational biography in order to examine the achievement of selected, non-traditional groups of students. Both lines of research appear to lack integration and often fail to take organisational diversity into account, such as different types of higher education institutions or degree programmes. For a more comprehensive understanding of student diversity, the present study includes individual, social and organisational factors. To gain insights into their role for the transition to higher education, we examine how the different factors affect the students' perception of the formal and informal requirements of the first year as more or less difficult to cope with. As the perceived requirements result from both the characteristics of the students and the institutional context, they allow to investigate transition at the interface of the micro and the meso level of higher education. Latent profile analyses revealed that there are no profiles with complex patterns of perception of the first-year requirements, but the identified groups rather differ in the overall level of perceived challenges. Moreover, SEM indicates that the differences in the perception largely depend on the individual factors self-efficacy and volition.}, language = {en} } @article{HugenrothNeidlinEngelmannetal.2021, author = {Hugenroth, Kristin and Neidlin, Michael and Engelmann, Ulrich M. and Kaufmann, Tim A. S. and Steinseifer, Ulrich and Heilmann, Torsten}, title = {Tipless Transseptal Cannula Concept Combines Improved Hemodynamic Properties and Risk-Reduced Placement: an In Silico Proof-of-Concept}, series = {Artificial Organs}, journal = {Artificial Organs}, number = {Accepted Article}, publisher = {Wiley}, address = {Weinheim}, issn = {1525-1594}, doi = {10.1111/aor.13964}, year = {2021}, language = {en} } @article{GivanoudiCornelisRasschaertetal.2021, author = {Givanoudi, Stella and Cornelis, Peter and Rasschaert, Geertrui and Wackers, Gideon and Iken, Heiko and Rolka, David and Yongabi, Derick and Robbens, Johan and Sch{\"o}ning, Michael Josef and Heyndrickx, Marc and Wagner, Patrick}, title = {Selective Campylobacter detection and quantification in poultry: A sensor tool for detecting the cause of a common zoonosis at its source}, series = {Sensors and Actuators B: Chemical}, journal = {Sensors and Actuators B: Chemical}, number = {In Press, Journal Pre-proof}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2021.129484}, pages = {Article 129484}, year = {2021}, language = {en} } @article{WerkhausenWillwacherAlbracht2021, author = {Werkhausen, Amelie and Willwacher, Steffen and Albracht, Kirsten}, title = {Medial gastrocnemius muscle fascicles shorten throughout stance during sprint acceleration}, series = {Scandinavian Journal of Medicine \& Science in Sports}, volume = {31}, journal = {Scandinavian Journal of Medicine \& Science in Sports}, number = {7}, publisher = {Wiley-Blackwell}, address = {Oxford}, issn = {0905-7188 (Druckausgabe)}, doi = {10.1111/sms.13956}, pages = {1471 -- 1480}, year = {2021}, abstract = {The compliant nature of distal limb muscle-tendon units is traditionally considered suboptimal in explosive movements when positive joint work is required. However, during accelerative running, ankle joint net mechanical work is positive. Therefore, this study aims to investigate how plantar flexor muscle-tendon behavior is modulated during fast accelerations. Eleven female sprinters performed maximum sprint accelerations from starting blocks, while gastrocnemius muscle fascicle lengths were estimated using ultrasonography. We combined motion analysis and ground reaction force measurements to assess lower limb joint kinematics and kinetics, and to estimate gastrocnemius muscle-tendon unit length during the first two acceleration steps. Outcome variables were resampled to the stance phase and averaged across three to five trials. Relevant scalars were extracted and analyzed using one-sample and two-sample t-tests, and vector trajectories were compared using statistical parametric mapping. We found that an uncoupling of muscle fascicle behavior from muscle-tendon unit behavior is effectively used to produce net positive mechanical work at the joint during maximum sprint acceleration. Muscle fascicles shortened throughout the first and second steps, while shortening occurred earlier during the first step, where negative joint work was lower compared with the second step. Elastic strain energy may be stored during dorsiflexion after touchdown since fascicles did not lengthen at the same time to dissipate energy. Thus, net positive work generation is accommodated by the reuse of elastic strain energy along with positive gastrocnemius fascicle work. Our results show a mechanism of how muscles with high in-series compliance can contribute to net positive joint work.}, language = {en} } @article{MontiWaldvogelRitzmannetal.2021, author = {Monti, Elena and Waldvogel, Janice and Ritzmann, Ramona and Freyler, Kathrin and Albracht, Kirsten and Helm, Michael and De Cesare, Niccol{\`o} and Pavan, Piero and Reggiani, Carlo and Gollhofer, Albert and Narici, Marco Vincenzo}, title = {Muscle in variable gravity: "I do not know where I am, but I know what to do"}, series = {Frontiers in Physiology}, volume = {12}, journal = {Frontiers in Physiology}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-042X}, doi = {10.3389/fphys.2021.714655}, pages = {19 Seiten}, year = {2021}, abstract = {Performing tasks, such as running and jumping, requires activation of the agonist and antagonist muscles before (motor unit pre-activation) and during movement performance (Santello and Mcdonagh, 1998). A well-timed and regulated muscle activation elicits a stretch-shortening cycle (SSC) response, naturally occurring in bouncing movements (Ishikawa and Komi, 2004; Taube et al., 2012). By definition, the SSC describes the stretching of a pre-activated muscle-tendon complex immediately followed by a muscle shortening in the concentric push-off phase (Komi, 1984). Given the importance of SSC actions for human movement, it is not surprising that many studies investigated the biomechanics of this phenomenon; in particular, drop jumps (DJs) represent a good paradigm to study muscle fascicle and tendon behavior in ballistic movements involving the SSC. Within a DJ, three main phases [pre-activation, braking, and push-off (PO; Komi, 2000)] have been recognized and extensively studied in common and challenging conditions, such as changes in load, falling height, or simulated hypo-gravity (Avela et al., 1994; Arampatzis et al., 2001; Fukashiro et al., 2005; Ishikawa et al., 2005; Sousa et al., 2007; Ritzmann et al., 2016; Helm et al., 2020). These studies show that the timing and amount of triceps-surae muscle-tendon unit pre-activation in DJs are differentially regulated based on the load applied to the muscle, being optimal in normal "Earth" gravity conditions (Avela et al., 1994), but decreased in simulated hypo-gravity, hyper-gravity (Avela et al., 1994; Ritzmann et al., 2016), or unknown conditions (i.e., unknown falling heights; Helm et al., 2020). Some authors indicated that, when falling from heights different from the optimal one [defined as the drop height giving a maximum DJ performance indicated as peak ground reaction force (GRF) or jump high], electromyographic (EMG) activity of the plantar flexors increases from lower than optimal to higher than optimal heights (Ishikawa and Komi, 2004; Sousa et al., 2007). These findings highlight the ability of the central nervous system to regulate the timing and amount of pre-activation according to different jumping conditions, thus regulating muscle fascicle length, tendon and joint stiffness as well as position, in order to safely land on the ground and quickly re-bounce. Similarly, to pre-activation, also in the braking phase, the plantar flexors are differentially regulated. In optimal height (i.e., load) jumping conditions, gastrocnemius medialis (GM) fascicles shorten at early ground contact (possibly due to the intervention of the stretch reflex; Gollhofer et al., 1992) and behave quasi-isometrically in the late braking phase, enabling tendon elongation, and storage of elastic energy (Gollhofer et al., 1992; Fukashiro et al., 2005; Sousa et al., 2007). When increasing the falling height (augmenting the impact GRF), the quasi-isometric behavior of fascicles disappears, and fast fascicle lengthening occurs (Ishikawa et al., 2005; Sousa et al., 2007). In the third and last PO phase, fascicles shorten and the tendon releases the elastic energy previously stored. Bobbert et al. (1987) reported no influence of jumping height on the work done and on the net vertical impulse assessed during PO; this observation suggests that, despite an optimal DJ performance might be achieved only in specific conditions (falling heights, loads), the central nervous system seems to be able to regulate muscle behavior in order to effectively perform the required task also in challenging situations. Although the regulation of triceps-surae muscle-tendon unit in DJs has been extensively investigated, very few studies focused on sarcomeres behavior during the performance of this SSC movement (Kurokawa et al., 2003; Fukashiro et al., 2005, 2006). Sarcomeres represent muscle contractile units and are known to express different amounts of force depending on their length (Gordon et al., 1966; Walker and Schrodt, 1974); thus, understanding the time course of their responses during DJs is fundamental to gain further insights into muscle force-generating capacity. In vivo measurement of sarcomere length in humans has been so far been performed only in static positions and under highly controlled experimental conditions (Llewellyn et al., 2008; Sanchez et al., 2015). Instead, human sarcomere length estimation (achieved by dividing GM measured fascicle length for a fixed sarcomere number) in dynamic contractions provided an indirect measure of sarcomere operating range during squat jump, countermovement jump, and DJ (Fukashiro et al., 2005, 2006; Kurokawa et al., 2003). The results of these studies showed that sarcomeres operate in the ascending limb of their length-tension (L-T) relationship in all types of jumps, and particularly so in DJ. However, most of the available observations on sarcomere and muscle fascicle behavior were made in condition of constant gravity. Thus, in order to understand how sarcomere and muscle fascicle length are regulated in variable gravity conditions, we performed experiments in a parabolic flight, involving variable gravity levels, ranging from about zero-g to about double the Earth's gravity (1 g; Waldvogel et al., 2021). Specifically, the aims of the present study were as follows: 1. To investigate the ability of the neuromuscular system in regulating fascicle length in response to conditions of variable gravity. 2. To estimate sarcomere operative length in the different DJ phases, in order to calculate its theoretical force production and its possible modulation in conditions of variable gravity. We hypothesized that muscle fascicles would be differentially regulated in different gravity conditions compared to 1 g, particularly in anticipation of landing and re-bouncing in unknown gravity levels. In addition, we hypothesized that sarcomeres would operate in the upper part of the ascending limb of their L-T relationship, possibly lengthening during the braking phase (especially in hyper-gravity) while operating quasi-isometrically in 1 g.}, language = {en} } @article{StaeudleSeynnesLapsetal.2021, author = {St{\"a}udle, Benjamin and Seynnes, Olivier and Laps, Guido and G{\"o}ll, Fabian and Br{\"u}ggemann, Gert-Peter and Albracht, Kirsten}, title = {Recovery from achilles tendon repair: a combination of Postsurgery Outcomes and Insufficient remodeling of muscle and tendon}, series = {Medicine \& Science in Sports \& Exercise}, volume = {53}, journal = {Medicine \& Science in Sports \& Exercise}, number = {7}, publisher = {American College of Sports Medicine}, address = {Philadelphia, Pa.}, issn = {1530-0315}, doi = {10.1249/MSS.0000000000002592}, pages = {1356 -- 1366}, year = {2021}, abstract = {Achilles tendon rupture (ATR) patients have persistent functional deficits in the triceps surae muscle-tendon unit (MTU). The complex remodeling of the MTU accompanying these deficits remains poorly understood. The purpose of the present study was to associate in vivo and in silico data to investigate the relations between changes inMTU properties and strength deficits inATR patients. Methods: Elevenmale subjects who had undergone surgical repair of complete unilateral ATR were examined 4.6 ± 2.0 (mean ± SD) yr after rupture. Gastrocnemius medialis (GM) tendon stiffness, morphology, and muscle architecture were determined using ultrasonography. The force-length relation of the plantar flexor muscles was assessed at five ankle joint angles. In addition, simulations (OpenSim) of the GM MTU force-length properties were performed with various iterations of MTU properties found between the unaffected and the affected side. Results: The affected side of the patients displayed a longer, larger, and stiffer GM tendon (13\% ± 10\%, 105\% ± 28\%, and 54\% ± 24\%, respectively) compared with the unaffected side. The GM muscle fascicles of the affected side were shorter (32\% ± 12\%) and with greater pennation angles (31\% ± 26\%). A mean deficit in plantarflexion moment of 31\% ± 10\% was measured. Simulations indicate that pairing an intact muscle with a longer tendon shifts the optimal angular range of peak force outside physiological angular ranges, whereas the shorter muscle fascicles and tendon stiffening seen in the affected side decrease this shift, albeit incompletely. Conclusions: These results suggest that the substantial changes in MTU properties found in ATR patients may partly result from compensatory remodeling, although this process appears insufficient to fully restore muscle function.}, language = {en} } @article{NeumaierWeissVeldemanetal.2021, author = {Neumaier, Felix and Weiss, Miriam and Veldeman, Michael and Kotliar, Konstantin and Wiesmann, Martin and Schulze-Steinen, Henna and H{\"o}llig, Anke and Clusmann, Hans and Schubert, Gerrit Alexander and Albanna, Walid}, title = {Changes in endogenous daytime melatonin levels after aneurysmal subarachnoid hemorrhage - preliminary findings from an observational cohort study}, series = {Clinical Neurology and Neurosurgery}, volume = {208}, journal = {Clinical Neurology and Neurosurgery}, number = {Article No.: 106870}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0303-8467}, doi = {10.1016/j.clineuro.2021.106870}, year = {2021}, abstract = {Aneurysmal subarachnoid hemorrhage (aSAH) is associated with early and delayed brain injury due to several underlying and interrelated processes, which include inflammation, oxidative stress, endothelial, and neuronal apoptosis. Treatment with melatonin, a cytoprotective neurohormone with anti-inflammatory, anti-oxidant and anti-apoptotic effects, has been shown to attenuate early brain injury (EBI) and to prevent delayed cerebral vasospasm in experimental aSAH models. Less is known about the role of endogenous melatonin for aSAH outcome and how its production is altered by the pathophysiological cascades initiated during EBI. In the present observational study, we analyzed changes in melatonin levels during the first three weeks after aSAH.}, language = {en} } @article{KuertenKotliarFuestetal.2021, author = {Kuerten, David and Kotliar, Konstantin and Fuest, Matthias and Walter, Peter and Hollstein, Muriel and Plange, Niklas}, title = {Does hemispheric vascular regulation differ significantly in glaucoma patients with altitudinal visual field asymmetry? A single-center, prospective study}, series = {International Ophthalmology}, volume = {41}, journal = {International Ophthalmology}, number = {41}, editor = {Neri, Piergiorgio}, publisher = {Springer}, address = {Berlin}, isbn = {1573-2630}, doi = {10.1007/s10792-021-01876-0}, pages = {3109 -- 3119}, year = {2021}, abstract = {Purpose Vascular risk factors and ocular perfusion are heatedly discussed in the pathogenesis of glaucoma. The retinal vessel analyzer (RVA, IMEDOS Systems, Germany) allows noninvasive measurement of retinal vessel regulation. Significant differences especially in the veins between healthy subjects and patients suffering from glaucoma were previously reported. In this pilot-study we investigated if localized vascular regulation is altered in glaucoma patients with altitudinal visual field defect asymmetry. Methods 15 eyes of 12 glaucoma patients with advanced altitudinal visual field defect asymmetry were included. The mean defect was calculated for each hemisphere separately (-20.99 ± 10.49 pro- found hemispheric visual field defect vs -7.36 ± 3.97 dB less profound hemisphere). After pupil dilation, RVA measurements of retinal arteries and veins were conducted using the standard protocol. The superior and inferior retinal vessel reactivity were measured consecutively in each eye. Results Significant differences were recorded in venous vessel constriction after flicker light stimulation and overall amplitude of the reaction (p \ 0.04 and p \ 0.02 respectively) in-between the hemispheres spheres. Vessel reaction was higher in the hemisphere corresponding to the more advanced visual field defect. Arterial diameters reacted similarly, failing to reach statistical significance. Conclusion Localized retinal vessel regulation is significantly altered in glaucoma patients with asymmetri altitudinal visual field defects. Veins supplying the hemisphere concordant to a less profound visual field defect show diminished diameter changes. Vascular dysregulation might be particularly important in early glaucoma stages prior to a significant visual field defect.}, language = {en} } @article{AlbannaConzenWeissetal.2021, author = {Albanna, Walid and Conzen, Catharina and Weiss, Miriam and Seyfried, Katharina and Kotliar, Konstantin and Schmidt, Tobias Philip and Kuerten, David and Hescheler, J{\"u}rgen and Bruecken, Anne and Schmidt-Trucks{\"a}ss, Arno and Neumaier, Felix and Wiesmann, Martin and Clusmann, Hans and Schubert, Gerrit Alexander}, title = {Non-invasive assessment of neurovascular coupling after aneurysmal subarachnoid hemorrhage: a prospective observational trial using retinal vessel analysis}, series = {Frontiers in Neurology}, volume = {12}, journal = {Frontiers in Neurology}, number = {12}, issn = {1664-2295}, doi = {10.3389/fneur.2021.690183}, pages = {1 -- 15}, year = {2021}, abstract = {Delayed cerebral ischemia (DCI) is a common complication after aneurysmal subarachnoid hemorrhage (aSAH) and can lead to infarction and poor clinical outcome. The underlying mechanisms are still incompletely understood, but animal models indicate that vasoactive metabolites and inflammatory cytokines produced within the subarachnoid space may progressively impair and partially invert neurovascular coupling (NVC) in the brain. Because cerebral and retinal microvasculature are governed by comparable regulatory mechanisms and may be connected by perivascular pathways, retinal vascular changes are increasingly recognized as a potential surrogate for altered NVC in the brain. Here, we used non-invasive retinal vessel analysis (RVA) to assess microvascular function in aSAH patients at different times after the ictus.}, language = {en} } @article{NeumaierKotliarHaerenetal.2021, author = {Neumaier, Felix and Kotliar, Konstantin and Haeren, Roel Hubert Louis and Temel, Yasin and L{\"u}ke, Jan Niklas and Seyam, Osama and Lindauer, Ute and Clusmann, Hans and Hescheler, J{\"u}rgen and Schubert, Gerrit Alexander and Schneider, Toni and Albanna, Walid}, title = {Retinal Vessel Responses to Flicker Stimulation Are Impaired in Ca v 2.3-Deficient Mice—An in- vivo Evaluation Using Retinal Vessel Analysis (RVA)}, series = {Frontiers in Neurology}, volume = {12}, journal = {Frontiers in Neurology}, publisher = {Frontiers}, doi = {10.3389/fneur.2021.659890}, pages = {1 -- 11}, year = {2021}, language = {en} } @article{FiedlerOrzadaFloeseretal.2021, author = {Fiedler, Thomas M. and Orzada, Stephan and Fl{\"o}ser, Martina and Rietsch, Stefan H. G. and Quick, Harald H. and Ladd, Mark E. and Bitz, Andreas}, title = {Performance analysis of integrated RF microstrip transmit antenna arrays with high channel count for body imaging at 7 T}, series = {NMR in Biomedicine}, volume = {34}, journal = {NMR in Biomedicine}, number = {7}, publisher = {Wiley}, address = {Weinheim}, issn = {0952-3480 (ISSN)}, doi = {10.1002/nbm.4515}, pages = {18 SeitenWiley}, year = {2021}, abstract = {The aim of the current study was to investigate the performance of integrated RF transmit arrays with high channel count consisting of meander microstrip antennas for body imaging at 7 T and to optimize the position and number of transmit ele- ments. RF simulations using multiring antenna arrays placed behind the bore liner were performed for realistic exposure conditions for body imaging. Simulations were performed for arrays with as few as eight elements and for arrays with high channel counts of up to 48 elements. The B1+ field was evaluated regarding the degrees of freedom for RF shimming in the abdomen. Worst-case specific absorption rate (SARwc ), SAR overestimation in the matrix compression, the number of virtual obser- vation points (VOPs) and SAR efficiency were evaluated. Constrained RF shimming was performed in differently oriented regions of interest in the body, and the devia- tion from a target B1+ field was evaluated. Results show that integrated multiring arrays are able to generate homogeneous B1+ field distributions for large FOVs, espe- cially for coronal/sagittal slices, and thus enable body imaging at 7 T with a clinical workflow; however, a low duty cycle or a high SAR is required to achieve homoge- neous B1+ distributions and to exploit the full potential. In conclusion, integrated arrays allow for high element counts that have high degrees of freedom for the pulse optimization but also produce high SARwc , which reduces the SAR accuracy in the VOP compression for low-SAR protocols, leading to a potential reduction in array performance. Smaller SAR overestimations can increase SAR accuracy, but lead to a high number of VOPs, which increases the computational cost for VOP evaluation and makes online SAR monitoring or pulse optimization challenging. Arrays with interleaved rings showed the best results in the study.}, language = {en} } @article{TemizArtmannKurulgandemirciFıratetal.2021, author = {Temiz Artmann, Ayseg{\"u}l and Kurulgan demirci, Eylem and F{\i}rat, Ipek Seda and Oflaz, Hakan and Artmann, Gerhard}, title = {Recombinant activated protein C (rhAPC) affects lipopolysaccharide-induced mechanical compliance changes and beat frequency of mESC-derived cardiomyocyte monolayers}, series = {SHOCK}, journal = {SHOCK}, publisher = {Wolters Kluwer}, address = {K{\"o}ln}, issn = {1540-0514}, doi = {10.1097/SHK.0000000000001845}, year = {2021}, language = {en} } @article{DickhoffHorikawaFunke2021, author = {Dickhoff, Jens and Horikawa, Atsushi and Funke, Harald}, title = {Hydrogen Combustion - new DLE Combustor Addresses NOx Emissions and Flashback}, series = {Turbomachinery international : the global journal of energy equipment}, volume = {62}, journal = {Turbomachinery international : the global journal of energy equipment}, number = {4}, publisher = {MJH Life Sciences}, address = {Cranbury}, issn = {2767-2328}, pages = {26 -- 27}, year = {2021}, language = {en} } @article{ButenwegKubalskiElDeibetal.2021, author = {Butenweg, Christoph and Kubalski, Thomas and El-Deib, Khaled and Gellert, Christoph}, title = {Erdbebennachweis von Mauerwerksbauten nach DIN EN 1998-1/NA-2021}, series = {Bautechnik : Zeitschrift f{\"u}r den gesamten Ingenieurbau}, volume = {98}, journal = {Bautechnik : Zeitschrift f{\"u}r den gesamten Ingenieurbau}, number = {11}, editor = {Jesse, Dirk}, publisher = {Ernst \& Sohn}, address = {Berlin}, issn = {1437-0999}, doi = {10.1002/bate.202100064}, pages = {852 -- 863}, year = {2021}, abstract = {Mauerwerksbauten in Deutschland sind mit Einf{\"u}hrung des nationalen Anwendungsdokuments DIN EN 1998-1/NA auf Grundlage einer neuen probabilistischen Erdbebenkarte nachzuweisen. F{\"u}r erfolgreiche Erdbebennachweise {\"u}blicher Grundrissformen von Mauerwerksbauten stehen in dem zuk{\"u}nftigen Anwendungsdokument neue rechnerische Nachweism{\"o}glichkeiten zur Verf{\"u}gung, mit denen die Tragf{\"a}higkeitsreserven von Mauerwerksbauten in der Baupraxis mit einem {\"u}berschaubaren Aufwand besser in Ansatz gebracht werden k{\"o}nnen. Das Standardrechenverfahren ist weiterhin der kraftbasierte Nachweis, der nun mit h{\"o}heren Verhaltensbeiwerten im Vergleich zur DIN 4149 durchgef{\"u}hrt werden kann. Die h{\"o}heren Verhaltensbeiwerte basieren auf der besseren Ausnutzung der geb{\"a}udespezifischen Verformungsf{\"a}higkeit und Energiedissipation sowie der Lastumverteilung der Schubkr{\"a}fte im Grundriss mit Ansatz von Rahmentragwirkung durch Wand-Deckeninteraktionen. Alternativ dazu kann ein nichtlinearer Nachweis auf Grundlage von Pushover-Analysen zur Anwendung kommen. Vervollst{\"a}ndigt werden die Regelungen f{\"u}r Mauerwerksbauten durch neue Regelungen f{\"u}r nichttragende Innenw{\"a}nde und Außenmauerschalen. Der vorliegende Beitrag stellt die Grundlagen und Hintergr{\"u}nde der neuen rechnerischen Nachweise in DIN EN 1998-1/NA vor und demonstriert deren Anwendung an einem Beispiel aus der Praxis.}, language = {de} } @article{OertelBung2021, author = {Oertel, Mario and Bung, Daniel Bernhard}, title = {Hochwasserschutz - eine Aufgabe f{\"u}r eine nachhaltige Wasserwirtschaft}, series = {Wasserwirtschaft}, volume = {111}, journal = {Wasserwirtschaft}, number = {9-10}, publisher = {Springer Vieweg}, address = {Wiesbaden}, issn = {0043-0978}, pages = {3 -- 19}, year = {2021}, language = {de} } @article{SeefeldtDachwald2021, author = {Seefeldt, Patric and Dachwald, Bernd}, title = {Temperature increase on folded solar sail membranes}, series = {Advances in Space Research}, volume = {67}, journal = {Advances in Space Research}, number = {9}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0273-1177}, doi = {10.1016/j.asr.2020.09.026}, pages = {2688 -- 2695}, year = {2021}, language = {en} } @article{ValeroSchalkoFriedrichetal.2021, author = {Valero, Daniel and Schalko, Isabella and Friedrich, Heide and Abad, Jorge D. and Bung, Daniel Bernhard and Donchyts, Gennadii and Felder, Stefan and Ferreira, Rui M. L. and Hohermuth, Benjamin and Kramer, Matthias and Li, Danxun and Mendes, Luis and Moreno-Rodenas, Antonio and Nones, Michael and Paron, Paolo and Ruiz-Villanueva, Virginia and Wang, Ruo-Qian and Franca, Mario J.}, title = {Pathways towards democratization of hydro-environment observations and data}, series = {Iahr White Paper Series}, journal = {Iahr White Paper Series}, number = {1}, publisher = {International Association for Hydro-Environment Engineering and Research (IAHR)}, pages = {1 -- 9}, year = {2021}, language = {en} } @article{GermanMikuckiWelchetal.2021, author = {German, Laura and Mikucki, Jill A. and Welch, Susan A. and Welch, Kathleen A. and Lutton, Anthony and Dachwald, Bernd and Kowalski, Julia and Heinen, Dirk and Feldmann, Marco and Francke, Gero and Espe, Clemens and Lyons, W. Berry}, title = {Validation of sampling antarctic subglacial hypersaline waters with an electrothermal ice melting probe (IceMole) for environmental analytical geochemistry}, series = {International Journal of Environmental Analytical Chemistry}, volume = {101}, journal = {International Journal of Environmental Analytical Chemistry}, number = {15}, publisher = {Taylor \& Francis}, address = {London}, issn = {0306-7319}, doi = {10.1080/03067319.2019.1704750}, pages = {2654 -- 2667}, year = {2021}, abstract = {Geochemical characterisation of hypersaline waters is difficult as high concentrations of salts hinder the analysis of constituents at low concentrations, such as trace metals, and the collection of samples for trace metal analysis in natural waters can be easily contaminated. This is particularly the case if samples are collected by non-conventional techniques such as those required for aquatic subglacial environments. In this paper we present the first analysis of a subglacial brine from Taylor Valley, (~ 78°S), Antarctica for the trace metals: Ba, Co, Mo, Rb, Sr, V, and U. Samples were collected englacially using an electrothermal melting probe called the IceMole. This probe uses differential heating of a copper head as well as the probe's sidewalls and an ice screw at the melting head to move through glacier ice. Detailed blanks, meltwater, and subglacial brine samples were collected to evaluate the impact of the IceMole and the borehole pump, the melting and collection process, filtration, and storage on the geochemistry of the samples collected by this device. Comparisons between melt water profiles through the glacier ice and blank analysis, with published studies on ice geochemistry, suggest the potential for minor contributions of some species Rb, As, Co, Mn, Ni, NH4+, and NO2-+NO3- from the IceMole. The ability to conduct detailed chemical analyses of subglacial fluids collected with melting probes is critical for the future exploration of the hundreds of deep subglacial lakes in Antarctica.}, language = {en} } @article{KoehlerRoepkeWolf2021, author = {K{\"o}hler, Klemens and R{\"o}pke, Ren{\´e} and Wolf, Martin R.}, title = {Through a mirror darkly - On the obscurity of teaching goals in game-based learning in IT security}, series = {ISAGA 2019: Simulation Gaming Through Times and Disciplines}, journal = {ISAGA 2019: Simulation Gaming Through Times and Disciplines}, publisher = {Springer}, address = {Cham}, doi = {10.1007/978-3-030-72132-9_6}, pages = {61 -- 73}, year = {2021}, abstract = {Teachers and instructors use very specific language communicating teaching goals. The most widely used frameworks of common reference are the Bloom's Taxonomy and the Revised Bloom's Taxonomy. The latter provides distinction of 209 different teaching goals which are connected to methods. In Competence Developing Games (CDGs - serious games to convey knowledge) and in IT security education, a two- or three level typology exists, reducing possible learning outcomes to awareness, training, and education. This study explores whether this much simpler framework succeeds in achieving the same range of learning outcomes. Method wise a keyword analysis was conducted. The results were threefold: 1. The words used to describe teaching goals in CDGs on IT security education do not reflect the whole range of learning outcomes. 2. The word choice is nevertheless different from common language, indicating an intentional use of language. 3. IT security CDGs use different sets of terms to describe learning outcomes, depending on whether they are awareness, training, or education games. The interpretation of the findings is that the reduction to just three types of CDGs reduces the capacity to communicate and think about learning outcomes and consequently reduces the outcomes that are intentionally achieved.}, language = {en} } @article{ElDeibButenwegKlinkel2021, author = {El-Deib, Khaled and Butenweg, Christoph and Klinkel, Sven}, title = {Erdbebennachweis von Mauerwerksbauten mit realistischen Modellen und erh{\"o}hten Verhaltensbeiwerten}, series = {Mauerwerk}, volume = {2021}, journal = {Mauerwerk}, number = {3}, editor = {Jesse, Dirk}, publisher = {Wiley}, address = {Weinheim}, issn = {1437-1022}, doi = {10.1002/dama.202110014}, pages = {110 -- 119}, year = {2021}, abstract = {Die Anwendung des linearen Nachweiskonzepts auf Mauerwerksbauten f{\"u}hrt dazu, dass bereits heute Standsicherheitsnachweise f{\"u}r Geb{\"a}ude mit {\"u}blichen Grundrissen in Gebieten mit moderaten Erdbebeneinwirkungen nicht mehr gef{\"u}hrt werden k{\"o}nnen. Diese Problematik wird sich in Deutschland mit der Einf{\"u}hrung kontinuierlicher probabilistischer Erdbebenkarten weiter versch{\"a}rfen. Aufgrund der Erh{\"o}hung der seismischen Einwirkungen, die sich vielerorts ergibt, ist es erforderlich, die vorhandenen, bislang nicht ber{\"u}cksichtigten Tragf{\"a}higkeitsreserven in nachvollziehbaren Nachweiskonzepten in der Baupraxis verf{\"u}gbar zu machen. Der vorliegende Beitrag stellt ein Konzept f{\"u}r die geb{\"a}udespezifische Ermittlung von erh{\"o}hten Verhaltensbeiwerten vor. Die Verhaltensbeiwerte setzen sich aus drei Anteilen zusammen, mit denen die Lastumverteilung im Grundriss, die Verformungsf{\"a}higkeit und Energiedissipation sowie die {\"U}berfestigkeiten ber{\"u}cksichtigt werden. F{\"u}r die rechnerische Ermittlung dieser drei Anteile wird ein nichtlineares Nachweiskonzept auf Grundlage von Pushover-Analysen vorgeschlagen, in denen die Interaktionen von W{\"a}nden und Geschossdecken durch einen Einspanngrad beschrieben werden. F{\"u}r die Bestimmung der Einspanngrade wird ein nichtlinearer Modellierungsansatz eingef{\"u}hrt, mit dem die Interaktion von W{\"a}nden und Decken abgebildet werden kann. Die Anwendung des Konzepts mit erh{\"o}hten geb{\"a}udespezifischen Verhaltensbeiwerten wird am Beispiel eines Mehrfamilienhauses aus Kalksandsteinen demonstriert. Die Ergebnisse der linearen Nachweise mit erh{\"o}hten Verhaltensbeiwerten f{\"u}r dieses Geb{\"a}ude liegen deutlich n{\"a}her an den Ergebnissen nichtlinearer Nachweise und somit bleiben {\"u}bliche Grundrisse in Erdbebengebieten mit den traditionellen linearen Rechenans{\"a}tzen nachweisbar.}, language = {de} } @article{KaschSchmidtJahnetal.2021, author = {Kasch, Susanne and Schmidt, Thomas and Jahn, Simon and Eichler, Fabian and Thurn, Laura and Bremen, Sebastian}, title = {L{\"o}sungsans{\"a}tze und Verfahrenskonzepte zum Laserstrahlschmelzen von Glas}, series = {Schweissen und Schneiden}, volume = {73}, journal = {Schweissen und Schneiden}, number = {Heft 1-2}, publisher = {DVS Verlag}, address = {D{\"u}sseldorf}, isbn = {0036-7184}, pages = {32 -- 39}, year = {2021}, language = {de} } @article{PoghossianSchoening2021, author = {Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Recent progress in silicon-based biologically sensitive field-effect devices}, series = {Current Opinion in Electrochemistry}, journal = {Current Opinion in Electrochemistry}, number = {Article number: 100811}, publisher = {Elsevier}, address = {Amsterdam}, issn = {2451-9103}, doi = {10.1016/j.coelec.2021.100811}, year = {2021}, abstract = {Biologically sensitive field-effect devices (BioFEDs) advantageously combine the electronic field-effect functionality with the (bio)chemical receptor's recognition ability for (bio)chemical sensing. In this review, basic and widely applied device concepts of silicon-based BioFEDs (ion-sensitive field-effect transistor, silicon nanowire transistor, electrolyte-insulator-semiconductor capacitor, light-addressable potentiometric sensor) are presented and recent progress (from 2019 to early 2021) is discussed. One of the main advantages of BioFEDs is the label-free sensing principle enabling to detect a large variety of biomolecules and bioparticles by their intrinsic charge. The review encompasses applications of BioFEDs for the label-free electrical detection of clinically relevant protein biomarkers, deoxyribonucleic acid molecules and viruses, enzyme-substrate reactions as well as recording of the cell acidification rate (as an indicator of cellular metabolism) and the extracellular potential.}, language = {en} } @article{BallVoegeleGrajewskietal.2021, author = {Ball, Christopher Stephen and V{\"o}gele, Stefan and Grajewski, Matthias and Kuckshinrichs, Wilhelm}, title = {E-mobility from a multi-actor point of view: Uncertainties and their impacts}, series = {Technological Forecasting and Social Change}, volume = {170}, journal = {Technological Forecasting and Social Change}, number = {Art. 120925}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {0040-1625}, doi = {10.1016/j.techfore.2021.120925}, year = {2021}, language = {en} } @article{JablonskiPoghossianSeverinetal.2021, author = {Jablonski, Melanie and Poghossian, Arshak and Severin, Robin and Keusgen, Michael and Wege, Christian and Sch{\"o}ning, Michael Josef}, title = {Capacitive Field-Effect Biosensor Studying Adsorption of Tobacco Mosaic Virus Particles}, series = {Micromachines}, volume = {12}, journal = {Micromachines}, number = {1}, publisher = {MDPI}, address = {Basel}, doi = {10.3390/mi12010057}, pages = {Artikel 57}, year = {2021}, abstract = {Plant virus-like particles, and in particular, tobacco mosaic virus (TMV) particles, are increasingly being used in nano- and biotechnology as well as for biochemical sensing purposes as nanoscaffolds for the high-density immobilization of receptor molecules. The sensitive parameters of TMV-assisted biosensors depend, among others, on the density of adsorbed TMV particles on the sensor surface, which is affected by both the adsorption conditions and surface properties of the sensor. In this work, Ta₂O₅-gate field-effect capacitive sensors have been applied for the label-free electrical detection of TMV adsorption. The impact of the TMV concentration on both the sensor signal and the density of TMV particles adsorbed onto the Ta₂O₅-gate surface has been studied systematically by means of field-effect and scanning electron microscopy methods. In addition, the surface density of TMV particles loaded under different incubation times has been investigated. Finally, the field-effect sensor also demonstrates the label-free detection of penicillinase immobilization as model bioreceptor on TMV particles.}, language = {en} } @article{HarzheimMuehmelHeuermann2021, author = {Harzheim, Thomas and M{\"u}hmel, Marc and Heuermann, Holger}, title = {A SFCW harmonic radar system for maritime search and rescue using passive and active tags}, series = {International Journal of Microwave and Wireless Technologies}, volume = {13}, journal = {International Journal of Microwave and Wireless Technologies}, number = {Special Issue 7}, publisher = {Cambridge University Press}, address = {Cambridge}, doi = {10.1017/S1759078721000520}, pages = {691 -- 707}, year = {2021}, abstract = {This paper introduces a new maritime search and rescue system based on S-band illumination harmonic radar (HR). Passive and active tags have been developed and tested while attached to life jackets and a small boat. In this demonstration test carried out on the Baltic Sea, the system was able to detect and range the active tags up to a distance of 5800 m using an illumination signal transmit-power of 100 W. Special attention is given to the development, performance, and conceptual differences between passive and active tags used in the system. Guidelines for achieving a high HR dynamic range, including a system components description, are given and a comparison with other HR systems is performed. System integration with a commercial maritime X-band navigation radar is shown to demonstrate a solution for rapid search and rescue response and quick localization.}, language = {en} } @article{Golland2021, author = {Golland, Alexander}, title = {Das Telekommunikation-Telemedien-Datenschutzgesetz. Cookies und PIMS als Herausforderungen f{\"u}r Website-Betreiber}, series = {NJW Neue Juristische Wochenschrift}, journal = {NJW Neue Juristische Wochenschrift}, number = {31}, editor = {Ewer, Wolfgang and Hamm, Rainer and Karpenstein, Ulrich and Oberth{\"u}r, Nathalie and Herchen, Hilke and Br{\"a}utigam, Peter}, publisher = {Beck}, address = {M{\"u}nchen}, issn = {0341-1915}, pages = {2238 -- 2243}, year = {2021}, language = {de} } @article{MonakhovaDiehl2021, author = {Monakhova, Yulia and Diehl, Bernd W.K.}, title = {Novel approach of qNMR workflow by standardization using 2H integral: Application to any intrinsic calibration standard}, series = {Talanta}, volume = {222}, journal = {Talanta}, number = {Article number: 121504}, publisher = {Elsevier}, isbn = {0039-9140}, doi = {10.1016/j.talanta.2020.121504}, year = {2021}, abstract = {Quantitative nuclear magnetic resonance (qNMR) is routinely performed by the internal or external standardization. The manuscript describes a simple alternative to these common workflows by using NMR signal of another active nuclei of calibration compound. For example, for any arbitrary compound quantification by NMR can be based on the use of an indirect concentration referencing that relies on a solvent having both 1H and 2H signals. To perform high-quality quantification, the deuteration level of the utilized deuterated solvent has to be estimated. In this contribution the new method was applied to the determination of deuteration levels in different deuterated solvents (MeOD, ACN, CDCl3, acetone, benzene, DMSO-d6). Isopropanol-d6, which contains a defined number of deuterons and protons, was used for standardization. Validation characteristics (precision, accuracy, robustness) were calculated and the results showed that the method can be used in routine practice. Uncertainty budget was also evaluated. In general, this novel approach, using standardization by 2H integral, benefits from reduced sample preparation steps and uncertainties, and can be applied in different application areas (purity determination, forensics, pharmaceutical analysis, etc.).}, language = {en} } @article{EngelmannShalabyShashaetal.2021, author = {Engelmann, Ulrich M. and Shalaby, Ahmed and Shasha, Carolyn and Krishnan, Kannan M. and Krause, Hans-Joachim}, title = {Comparative modeling of frequency mixing measurements of magnetic nanoparticles using micromagnetic simulations and Langevin theory}, series = {Nanomaterials}, volume = {11}, journal = {Nanomaterials}, number = {5}, publisher = {MDPI}, address = {Basel}, isbn = {2079-4991}, doi = {10.3390/nano11051257}, pages = {1 -- 16}, year = {2021}, abstract = {Dual frequency magnetic excitation of magnetic nanoparticles (MNP) enables enhanced biosensing applications. This was studied from an experimental and theoretical perspective: nonlinear sum-frequency components of MNP exposed to dual-frequency magnetic excitation were measured as a function of static magnetic offset field. The Langevin model in thermodynamic equilibrium was fitted to the experimental data to derive parameters of the lognormal core size distribution. These parameters were subsequently used as inputs for micromagnetic Monte-Carlo (MC)-simulations. From the hysteresis loops obtained from MC-simulations, sum-frequency components were numerically demodulated and compared with both experiment and Langevin model predictions. From the latter, we derived that approximately 90\% of the frequency mixing magnetic response signal is generated by the largest 10\% of MNP. We therefore suggest that small particles do not contribute to the frequency mixing signal, which is supported by MC-simulation results. Both theoretical approaches describe the experimental signal shapes well, but with notable differences between experiment and micromagnetic simulations. These deviations could result from Brownian relaxations which are, albeit experimentally inhibited, included in MC-simulation, or (yet unconsidered) cluster-effects of MNP, or inaccurately derived input for MC-simulations, because the largest particles dominate the experimental signal but concurrently do not fulfill the precondition of thermodynamic equilibrium required by Langevin theory.}, language = {en} } @article{SaretzkiBergmannDahmannetal.2021, author = {Saretzki, Charlotte and Bergmann, Ole and Dahmann, Peter and Janser, Frank and Keimer, Jona and Machado, Patricia and Morrison, Audry and Page, Henry and Pluta, Emil and St{\"u}bing, Felix and K{\"u}pper, Thomas}, title = {Are small airplanes safe with regards to COVID-19 transmission?}, series = {Journal of Travel Medicine}, volume = {28}, journal = {Journal of Travel Medicine}, number = {7}, publisher = {Oxford University Press}, address = {Oxford}, issn = {1708-8305}, doi = {10.1093/jtm/taab105}, year = {2021}, language = {en} } @article{KarschuckKaulenPoghossianetal.2021, author = {Karschuck, Tobias and Kaulen, Corinna and Poghossian, Arshak and Wagner, Patrick H. and Sch{\"o}ning, Michael Josef}, title = {Gold nanoparticle-modified capacitive field-effect sensors: Studying the surface density of nanoparticles and coupling of charged polyelectrolyte macromolecules}, series = {Electrochemical Science Advances}, volume = {2}, journal = {Electrochemical Science Advances}, number = {5}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0938-5193}, doi = {10.1002/elsa.202100179}, pages = {10 Seiten}, year = {2021}, abstract = {The coupling of ligand-stabilized gold nanoparticles with field-effect devices offers new possibilities for label-free biosensing. In this work, we study the immobilization of aminooctanethiol-stabilized gold nanoparticles (AuAOTs) on the silicon dioxide surface of a capacitive field-effect sensor. The terminal amino group of the AuAOT is well suited for the functionalization with biomolecules. The attachment of the positively-charged AuAOTs on a capacitive field-effect sensor was detected by direct electrical readout using capacitance-voltage and constant capacitance measurements. With a higher particle density on the sensor surface, the measured signal change was correspondingly more pronounced. The results demonstrate the ability of capacitive field-effect sensors for the non-destructive quantitative validation of nanoparticle immobilization. In addition, the electrostatic binding of the polyanion polystyrene sulfonate to the AuAOT-modified sensor surface was studied as a model system for the label-free detection of charged macromolecules. Most likely, this approach can be transferred to the label-free detection of other charged molecules such as enzymes or antibodies.}, language = {en} } @article{Finkenberger2021, author = {Finkenberger, Isabel Maria}, title = {Wohnen als Produktionsgemeinschaftsaufgabe}, series = {Jahrbuch f{\"u}r Christliche Sozialwissenschaften}, journal = {Jahrbuch f{\"u}r Christliche Sozialwissenschaften}, number = {62}, publisher = {Aschendorff}, address = {M{\"u}nster}, issn = {0075-2584}, doi = {10.17879/jcsw-2021-3537}, pages = {31 -- 42}, year = {2021}, abstract = {Wohnen als neue soziale Frage ist mehr als die Produktion neuer Formen von Wohnen und deren architektonischer Gestalt, und auch mehr als nur die Umsetzung sich ver{\"a}ndernder, jedoch individuell formulierter Wohnw{\"u}nsche. Sie spannt sich auf zwischen gesellschafts- und nachhaltigkeitspolitischen, hardcore-kapitalistischen und globalen Rahmenbedingungen, Hardware und Software, Individuum und Gemeinwohl, Konsum und Mitgestaltung. Entscheidend sind die Akteure und die Art und Weise, wie und nach welchen Maßst{\"a}ben sie handeln. Entscheidend ist aber auch, Wohnen sowohl kontextuell wie auch programmatisch neu zu denken und dadurch zu neuen Mischungen, Nachbarschaften und Bewertungskriterien einer Projekt- und Stadtentwicklung zu kommen, die mehr als die Summe seiner Einzelteile wollen - ein gutes Leben f{\"u}r Alle abseits der Frage des Geldbeutels und der sozialen Zugeh{\"o}rigkeit.}, language = {de} } @article{HacklBuessKammerlohretal.2021, author = {Hackl, Michael and Buess, Eduard and Kammerlohr, Sandra and Nacov, Julia and Staat, Manfred and Leschinger, Tim and M{\"u}ller, Lars P. and Wegmann, Kilian}, title = {A "comma sign"-directed subscapularis repair in anterosuperior rotator cuff tears yields biomechanical advantages in a cadaveric model}, series = {The american journal of sports medicine}, volume = {49}, journal = {The american journal of sports medicine}, number = {12}, publisher = {Sage}, address = {London}, issn = {1552-3365}, doi = {10.1177/03635465211031506}, pages = {3212 -- 3217}, year = {2021}, abstract = {Background: Additional stabilization of the "comma sign" in anterosuperior rotator cuff repair has been proposed to provide biomechanical benefits regarding stability of the repair. Purpose: This in vitro investigation aimed to investigate the influence of a comma sign-directed reconstruction technique for anterosuperior rotator cuff tears on the primary stability of the subscapularis tendon repair. Study Design: Controlled laboratory study. Methods: A total of 18 fresh-frozen cadaveric shoulders were used in this study. Anterosuperior rotator cuff tears (complete full-thickness tear of the supraspinatus and subscapularis tendons) were created, and supraspinatus repair was performed with a standard suture bridge technique. The subscapularis was repaired with either a (1) single-row or (2) comma sign technique. A high-resolution 3D camera system was used to analyze 3-mm and 5-mm gap formation at the subscapularis tendon-bone interface upon incremental cyclic loading. Moreover, the ultimate failure load of the repair was recorded. A Mann-Whitney test was used to assess significant differences between the 2 groups. Results: The comma sign repair withstood significantly more loading cycles than the single-row repair until 3-mm and 5-mm gap formation occurred (P≤ .047). The ultimate failure load did not reveal any significant differences when the 2 techniques were compared (P = .596). Conclusion: The results of this study show that additional stabilization of the comma sign enhanced the primary stability of subscapularis tendon repair in anterosuperior rotator cuff tears. Although this stabilization did not seem to influence the ultimate failure load, it effectively decreased the micromotion at the tendon-bone interface during cyclic loading. Clinical Relevance: The proposed technique for stabilization of the comma sign has shown superior biomechanical properties in comparison with a single-row repair and might thus improve tendon healing. Further clinical research will be necessary to determine its influence on the functional outcome.}, language = {en} } @article{Gaigall2021, author = {Gaigall, Daniel}, title = {Test for Changes in the Modeled Solvency Capital Requirement of an Internal Risk Model}, series = {ASTIN Bulletin}, volume = {51}, journal = {ASTIN Bulletin}, number = {3}, publisher = {Cambridge Univ. Press}, address = {Cambridge}, issn = {1783-1350}, doi = {10.1017/asb.2021.20}, pages = {813 -- 837}, year = {2021}, abstract = {In the context of the Solvency II directive, the operation of an internal risk model is a possible way for risk assessment and for the determination of the solvency capital requirement of an insurance company in the European Union. A Monte Carlo procedure is customary to generate a model output. To be compliant with the directive, validation of the internal risk model is conducted on the basis of the model output. For this purpose, we suggest a new test for checking whether there is a significant change in the modeled solvency capital requirement. Asymptotic properties of the test statistic are investigated and a bootstrap approximation is justified. A simulation study investigates the performance of the test in the finite sample case and confirms the theoretical results. The internal risk model and the application of the test is illustrated in a simplified example. The method has more general usage for inference of a broad class of law-invariant and coherent risk measures on the basis of a paired sample.}, language = {en} }