@article{KraftHeerRetkowitz2008, author = {Kraft, Bodo and Heer, Thomas and Retkowitz, Daniel}, title = {Algorithm and Tool for Ontology Integration Based on Graph Rewriting / Heer, Thomas ; Retkowitz, Daniel ; Kraft, Bodo}, series = {Applications of Graph Transformations with Industrial Relevance / Third International Symposium, AGTIVE 2007, Kassel, Germany, October 10-12, 2007, Revised Selected and Invited Papers}, journal = {Applications of Graph Transformations with Industrial Relevance / Third International Symposium, AGTIVE 2007, Kassel, Germany, October 10-12, 2007, Revised Selected and Invited Papers}, isbn = {978-3-540-89019-5}, pages = {577 -- 582}, year = {2008}, language = {en} } @article{Dikta2008, author = {Dikta, Gerhard}, title = {The Bootstrap in Binary Model Diagnostics}, series = {Frontiers of applied and computational mathematics : New Jersey Institute of Technology, USA, 19 - 21 May 2008 ; [dedicated to Daljit Singh Ahluwalia on his 75th birthday ; Fifth Annual Frontiers in Applied and Computational Mathematics Conference (FACM '08) ; selection of papers] / ed. by Denis Blackmore}, journal = {Frontiers of applied and computational mathematics : New Jersey Institute of Technology, USA, 19 - 21 May 2008 ; [dedicated to Daljit Singh Ahluwalia on his 75th birthday ; Fifth Annual Frontiers in Applied and Computational Mathematics Conference (FACM '08) ; selection of papers] / ed. by Denis Blackmore}, publisher = {World Scientific}, address = {Hackensack, NJ [u.a.]}, isbn = {978-981-283-528-4}, pages = {119 -- 126}, year = {2008}, language = {en} } @article{AggarwalDhimanKumaretal.2012, author = {Aggarwal, P. and Dhiman, S. and Kumar, G. and Scherer, Ulrich W. and Singla, M. L. and Srivastava, A.}, title = {Optical study of poly(ethyleneterephthalate) modified by different ionizing radiation dose}, series = {Indian Journal of Pure and Applied Physics}, volume = {50}, journal = {Indian Journal of Pure and Applied Physics}, number = {2}, issn = {0019-5596}, pages = {129 -- 132}, year = {2012}, abstract = {Thin films of poly(ethyleneterephthalate) [PET]were exposed to radiation dose ranging from 10 to 30 kGy by using gamma rays in the range 12.8-177.8 MGy using swift light ions of hydrogen. There was no effect of the radiation dose on the optical behaviour of PET as a result of exposure to radiation dose up to 30 kGy brought about by gamma rays but a significant decrease in the optical band gap values was observed when PET was exposed to swift light ions of hydrogen. The data obtained are discussed in terms of optical studies carried out on PET using swift heavy ions.}, language = {en} } @article{BergmannDemuthSander2011, author = {Bergmann, Sandra and Demuth, Bastian and Sander, Volker}, title = {A Web Framework for Workflow Submission and Monitoring via UNICORE 6 based on Distributable Scientific Workflow Templates}, series = {UNICORE Summit 2011 : proceedings, 7-8 July 2011, Torun, Poland / Mathilde Romberg ... (Eds.)}, journal = {UNICORE Summit 2011 : proceedings, 7-8 July 2011, Torun, Poland / Mathilde Romberg ... (Eds.)}, publisher = {Forschungszentrum J{\"u}lich}, address = {J{\"u}lich}, isbn = {9783893367504}, pages = {45 -- 50}, year = {2011}, language = {en} } @article{KrottGerhardsSkorupaetal.2011, author = {Krott, Daniel and Gerhards, Michael and Skorupa, Sascha and Sander, Volker}, title = {NHiLA - Bridging the Gap Between .NET and UNICORE}, series = {UNICORE Summit 2011 : proceedings, 7-8 July 2011, Torun, Poland / Mathilde Romberg ... (Eds.)}, journal = {UNICORE Summit 2011 : proceedings, 7-8 July 2011, Torun, Poland / Mathilde Romberg ... (Eds.)}, publisher = {Forschungszentrum J{\"u}lich}, address = {J{\"u}lich}, isbn = {9783893367504}, pages = {77 -- 86}, year = {2011}, language = {en} } @article{GerhardsSkorupaSanderetal.2011, author = {Gerhards, M. and Skorupa, S. and Sander, Volker and Pfeiffer, P. and Belloum, A.}, title = {Towards a security framework for a WS-HumanTask processor}, series = {7th International Conference on Network and Service Management (CNSM), 2011 Paris}, journal = {7th International Conference on Network and Service Management (CNSM), 2011 Paris}, publisher = {IEEE}, address = {New York}, isbn = {978-3-901882-44-9}, pages = {1 -- 5}, year = {2011}, language = {en} } @article{OehlschlaegerOsenPeileretal.2001, author = {{\"O}hlschl{\"a}ger, Peter and Osen, Wolfram and Peiler, Tanja and Caldeira, Sandra}, title = {A DNA vaccine based on a shuffled E7 oncogene of the human papillomavirus type 16 (HPV 16) induces E7-specific cytotoxic T cells but lacks transforming activity / Osen, Wolfram ; Peiler, Tanja ; {\"O}hlschl{\"a}ger, Peter ; Caldeira, Sandra ; Faath, Stefan ; Mich}, series = {Vaccine. 19 (2001), H. 20}, journal = {Vaccine. 19 (2001), H. 20}, isbn = {0264-410X}, pages = {4276 -- 4286}, year = {2001}, language = {en} } @article{OehlschlaegerSteinbergSehretal.2005, author = {{\"O}hlschl{\"a}ger, Peter and Steinberg, Thorsten and Sehr, Peter and Osen, Wolfram}, title = {Modification of HPV 16 E7 genes: correlation between the level of protein expression and CTL response after immunization of C57BL/6 mice / Steinberg, Thorsten ; {\"O}hlschl{\"a}ger, Peter ; Sehr, Peter ; Osen, Wolfram ; Gissmann, Lutz}, series = {Vaccine. 23 (2005), H. 9}, journal = {Vaccine. 23 (2005), H. 9}, isbn = {0264-410X}, pages = {1149 -- 1157}, year = {2005}, language = {en} } @article{OehlschlaegerPesOsenetal.2006, author = {{\"O}hlschl{\"a}ger, Peter and Pes, Michaela and Osen, Wolfram and D{\"u}rst, Matthias}, title = {An improved rearranged Human Papillomavirus Type 16 E7 DNA vaccine candidate (HPV-16 E7SH) induces an E7 wildtype-specific T cell response / {\"O}hlschl{\"a}ger, Peter ; Pes, Michaela ; Osen, Wolfram ; D{\"u}rst, Matthias ; Schneider, Achim ; Gissmann, Lutz ; Kaufman}, series = {Vaccine. 24 (2006), H. 15}, journal = {Vaccine. 24 (2006), H. 15}, isbn = {0264-410X}, pages = {2880 -- 2893}, year = {2006}, language = {en} } @article{OehlschlaegerMichelOsenetal.2002, author = {{\"O}hlschl{\"a}ger, Peter and Michel, Nico and Osen, Wolfram and Freyschmidt, Eva-Jasmin}, title = {T cell response to human papillomavirus 16 E7 in mice: comparison of Cr release assay, intracellular IFN-gamma production, ELISPOT and tetramer staining / Michel, Nico ; {\"O}hlschl{\"a}ger, Peter ; Osen, Wolfram ; Freyschmidt, Eva-Jasmin ; Gut{\"o}hrlein, Heidrun ;}, series = {Intervirology. 45 (2002)}, journal = {Intervirology. 45 (2002)}, isbn = {1423-0100}, pages = {290 -- 299}, year = {2002}, language = {en} } @article{OehlschlaegerOsenDelletal.2003, author = {{\"O}hlschl{\"a}ger, Peter and Osen, Wolfram and Dell, Kerstin and Faath, Stefan}, title = {Human papillomavirus type 16 L1 capsomeres induce L1-specific cytotoxic T lymphocytes and tumor regression in C57BL/6 mice / {\"O}hlschl{\"a}ger, Peter ; Osen, Wolfram ; Dell, Kerstin ; Faath, Stefan ; Garcea Robert L: ; Jochmus, Ingrid ; M{\"u}ller, Martin, Pawlita,}, series = {Journal of Virology. 77 (2003), H. 8}, journal = {Journal of Virology. 77 (2003), H. 8}, isbn = {1098-5514}, pages = {4635 -- 4645}, year = {2003}, language = {en} } @article{HartungReyMathieuetal.2004, author = {Hartung, Frank and Rey, J. and Mathieu, B. and Lozano, D.}, title = {Media aware overlay routing in Ambient Networks / Rey, J. ; Mathieu, B. ; Lozano, D. ; Herborn, S. ; Ahmed, K. ; Schmid, S. ; Goebbels, S. ; Hartung, F. ; Kampmann, M.}, series = {16th IEEE International Symposium on Personal, Indoor and Mobile Radio Communications, 2005. PIMRC 2005. Date:11-14 Sept. 2005 ; Vol. 2}, journal = {16th IEEE International Symposium on Personal, Indoor and Mobile Radio Communications, 2005. PIMRC 2005. Date:11-14 Sept. 2005 ; Vol. 2}, pages = {952 -- 957}, year = {2004}, language = {en} } @article{HartungKumwilaisak2004, author = {Hartung, Frank and Kumwilaisak, W.}, title = {An intraframe error concealment: nonlinear pattern alignment and directional interpolation / Kumwilaisak, W. ; Hartung, F.}, series = {Conference on Image Processing, 2004. ICIP '04. 2004 International / Vol. 2 .}, journal = {Conference on Image Processing, 2004. ICIP '04. 2004 International / Vol. 2 .}, pages = {825 -- 828}, year = {2004}, language = {en} } @article{AggarwalSinghSinghetal.2011, author = {Aggarwal, Prerna and Singh, Virendra and Singh, Arjun and Scherer, Ulrich W. and Singh, Tejvir and Singla, Madan L. and Srivastava, Alok}, title = {Physico-chemical transformations in swift heavy ion modified poly(ethyleneterephthalate)}, series = {Radiation Physics and Chemistry}, journal = {Radiation Physics and Chemistry}, publisher = {Pergamon Press}, address = {Oxford}, isbn = {0969-806X}, pages = {1 -- 28}, year = {2011}, language = {en} } @article{WagnerMiyamotoShigiharaetal.2011, author = {Wagner, Torsten and Miyamoto, Ko-ichiro and Shigihara, Noriko and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo}, title = {Microfluidic systems with free definable sensor spots by an integrated light-addressable potentiometric sensor}, series = {Procedia Engineering. 25 (2011)}, journal = {Procedia Engineering. 25 (2011)}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {1877-7058}, pages = {791 -- 794}, year = {2011}, language = {en} } @article{BohrnStuetzFuchsetal.2011, author = {Bohrn, U. and St{\"u}tz, E. and Fuchs, K. and Fleischer, M. and Sch{\"o}ning, Michael Josef and Wagner, P.}, title = {Air Quality Monitoring using a Whole-Cell based Sensor System}, series = {Procedia Engineering. 25 (2011)}, journal = {Procedia Engineering. 25 (2011)}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {1877-7058}, pages = {1421 -- 1424}, year = {2011}, language = {en} } @article{HartungNohBaccichetetal.2009, author = {Hartung, Frank and Noh, Jeonghun and Baccichet, Pierpaolo and Mavlankar, Aditya}, title = {Standford Peer-to-Peer Mulicast (SPPM) - Overview and recent Extensions / Noh, Jeonghun ; Baccichet, Pierpaolo ; Hartung, Frank ; Mavlankar, Aditya ; Girod, Bernd}, isbn = {978-1-4244-4593-6}, pages = {1 -- 4}, year = {2009}, language = {en} } @article{HartungHornHuschkeetal.2009, author = {Hartung, Frank and Horn, Uwe and Huschke, J{\"o}rg and Kampmann, Markus}, title = {MBMS—IP Multicast/Broadcast in 3G Networks / Hartung, Frank ; Horn, Uwe ; Huschke, J{\"o}rg ; Kampmann, Markus ; Lohmar, Thorsten}, series = {International Journal of Digital Multimedia Broadcasting. 2009 (2009)}, journal = {International Journal of Digital Multimedia Broadcasting. 2009 (2009)}, isbn = {1687-7586}, pages = {1 -- 25}, year = {2009}, language = {en} } @article{HartungKampmannHornetal.2007, author = {Hartung, Frank and Kampmann, Markus and Horn, Uwe and Kritzner, Jan}, title = {Mobile Television / Hartung, Frank ; Kampmann, Markus ; Horn, Uwe ; Kritzner, Jan}, series = {Encyclopedia of mobile computing and commerce / David Taniar ; Bd. 2 : Mobile ICT - Z}, journal = {Encyclopedia of mobile computing and commerce / David Taniar ; Bd. 2 : Mobile ICT - Z}, publisher = {Information Science Reference}, address = {Hershey}, isbn = {978-1-59904-002-8}, pages = {611 -- 615}, year = {2007}, language = {en} } @article{HartungHornHuschkeetal.2007, author = {Hartung, Frank and Horn, Uwe and Huschke, J{\"o}rg and Kampmann, Markus}, title = {Delivery of Broadcast Services in 3G Networks / Hartung, Frank ; Horn, Uwe ; J{\"o}rg Huschke ; Kampmann, Markus ; Lohmar, Thorsten ; Lundevall, Magnus}, series = {IEEE Transactions on Broastcasting. 53 (2007), H. 1 Part: 2}, journal = {IEEE Transactions on Broastcasting. 53 (2007), H. 1 Part: 2}, isbn = {0018-9316}, pages = {188 -- 199}, year = {2007}, language = {en} } @article{HartungHornHuschkeetal.2007, author = {Hartung, Frank and Horn, Uwe and Huschke, J{\"o}rg and Kampmann, Markus}, title = {Mobile TV Services in 3G Networks / Hartung, Frank ; Horn, Uwe ; Huschke, J{\"o}rg ; Kampmann, Markus ; Lohmar, Thorsten}, series = {KIVS 2007 : Kommunikation in verteilten Systemen : 15. ITG-GI-Fachtagung vom 26. Februar bis 2. M{\"a}rz 2007 in Bern, Schweiz ; Industriebeitr{\"a}ge, Kurzbeitr{\"a}ge und Workshops / T. Braun ... (Hrsg.)}, journal = {KIVS 2007 : Kommunikation in verteilten Systemen : 15. ITG-GI-Fachtagung vom 26. Februar bis 2. M{\"a}rz 2007 in Bern, Schweiz ; Industriebeitr{\"a}ge, Kurzbeitr{\"a}ge und Workshops / T. Braun ... (Hrsg.)}, isbn = {978-3-8007-2980-7}, pages = {15 -- 18}, year = {2007}, language = {en} } @article{HartungKampmann2007, author = {Hartung, Frank and Kampmann, Markus}, title = {Media Delivery Based on Service Aware Transport Overlay Networks / Kampmann, Markus ; Hartung, Frank}, series = {KIVS 2007 : Kommunikation in verteilten Systemen : 15. ITG-GI-Fachtagung vom 26. Februar bis 2. M{\"a}rz 2007 in Bern, Schweiz ; Industriebeitr{\"a}ge, Kurzbeitr{\"a}ge und Workshops / T. Braun ... (Hrsg.)}, journal = {KIVS 2007 : Kommunikation in verteilten Systemen : 15. ITG-GI-Fachtagung vom 26. Februar bis 2. M{\"a}rz 2007 in Bern, Schweiz ; Industriebeitr{\"a}ge, Kurzbeitr{\"a}ge und Workshops / T. Braun ... (Hrsg.)}, isbn = {978-3-8007-2980-7}, pages = {9 -- 10}, year = {2007}, language = {en} } @article{HartungKampmannHornetal.2007, author = {Hartung, Frank and Kampmann, M. and Horn, U. and Huschke, J.}, title = {Delivery of Mobile TV services in 3G cellular networks / Kampmann, M. ; Hartung, F. ; Horn, U. ; Huschke, J. ; Lohmar, T.}, series = {Elektronische Medien : Vortr{\"a}ge des 12. Dortmunder Fernsehseminars vom 20. bis 21. M{\"a}rz 2007 in Dortmund / Veranst.: ITG-FKTG-Fachbereich 3 ... Wiss. Tagungsleitung: R. Kays}, journal = {Elektronische Medien : Vortr{\"a}ge des 12. Dortmunder Fernsehseminars vom 20. bis 21. M{\"a}rz 2007 in Dortmund / Veranst.: ITG-FKTG-Fachbereich 3 ... Wiss. Tagungsleitung: R. Kays}, publisher = {VDE-Verl.}, address = {Berlin}, isbn = {978-3-8007-3019-3}, pages = {49 -- 52}, year = {2007}, language = {en} } @article{HartungDondetiCastleford2007, author = {Hartung, Frank and Dondeti, L. and Castleford, F.}, title = {Multimedia Internet KEYing (MIKEY) General Extension Payload for Open Mobile Alliance BCAST LTKM/STKM Transport / Dondeti, L. ; Castleford, D. ; Hartung, F.}, pages = {1 -- 7}, year = {2007}, language = {en} } @article{HartungSchiederKampmannetal.2006, author = {Hartung, Frank and Schieder, Andreas and Kampmann, Markus and Vorwerk, Marc}, title = {Network Supported Media Delivery in Ambient Networks (Netzwerkunterst{\"u}tzte Medienverteilung) / Schieder, Andreas ; Kampmann, Markus ; Hartung, Frank ; Vorwerk, Marc ; Rembarz, Ren{\´e}}, series = {it - Information Technology . 48 (2006), H. 5}, journal = {it - Information Technology . 48 (2006), H. 5}, isbn = {1611-2776}, pages = {264 -- 273}, year = {2006}, language = {en} } @article{HartungBaldoHornetal.2004, author = {Hartung, Frank and Baldo, N. and Horn, U. and Kampmann, M.}, title = {RTCP feedback based transmission rate control for 3G wireless multimedia streaming / Baldo, N. ; Horn, U. ; Kampmann, M. ; Hartung, F. ;}, series = {15th IEEE International Symposium on Personal, Indoor and Mobile Radio Communications, 2004. PIMRC 2004. Date:5-8 Sept. 2004 ; Vol. 3}, journal = {15th IEEE International Symposium on Personal, Indoor and Mobile Radio Communications, 2004. PIMRC 2004. Date:5-8 Sept. 2004 ; Vol. 3}, pages = {1817 -- 1821}, year = {2004}, language = {en} } @article{BohnFunkeGier1999, author = {Bohn, D. and Funke, Harald and Gier, J.}, title = {Numerical and Experimental Investigations on the Flow in a 4-Stage Turbine with Special Focus on the Development of a Radial Temperature Streak}, series = {ASME Turbo Expo 1999, Indianapolis, USA, 1999}, journal = {ASME Turbo Expo 1999, Indianapolis, USA, 1999}, year = {1999}, language = {en} } @article{FunkeReckerBosschaertsetal.2011, author = {Funke, Harald and Recker, E. and Bosschaerts, W. and Boonen, Q. and B{\"o}rner, Sebastian}, title = {Parametrical study of the „Micromix" hydrogen combustion principle}, series = {10th International Symposium on Experimental and Computational Aerothermodynamics of Internal Flows, ISAIF10-049, Brussels, Belgium, 4-7 July 2011}, journal = {10th International Symposium on Experimental and Computational Aerothermodynamics of Internal Flows, ISAIF10-049, Brussels, Belgium, 4-7 July 2011}, year = {2011}, language = {en} } @article{FunkeBoernerRobinsonetal.2010, author = {Funke, Harald and B{\"o}rner, Sebastian and Robinson, A. and Hendrick, P. and Recker, E.}, title = {Low NOx H2 combustion for industrial gas turbines of various power ranges}, series = {5th International Gas Turbine Conference ETN-IGTC, ETN-2010-42, Brussels, Belgium, October 2010}, journal = {5th International Gas Turbine Conference ETN-IGTC, ETN-2010-42, Brussels, Belgium, October 2010}, year = {2010}, language = {en} } @inproceedings{FunkeBoernerHendricketal.2013, author = {Funke, Harald and B{\"o}rner, Sebastian and Hendrick, P. and Recker, E. and Elsing, R.}, title = {Development and integration of a scalable low NOx combustion chamber for a hydrogen fuelled aero gas turbine}, series = {Progress in Propulsion Physics. - Vol. 4}, booktitle = {Progress in Propulsion Physics. - Vol. 4}, editor = {DeLuca, Luigi T.}, publisher = {EDP Sciences}, address = {[Les Ulis]}, isbn = {978-2-7598-0876-2}, doi = {10.1051/eucass/201304357}, pages = {357 -- 372}, year = {2013}, language = {en} } @article{EschFunkeRoosenetal.2011, author = {Esch, Thomas and Funke, Harald and Roosen, Peter and Jarolimek, Ulrich}, title = {Biogenic Vehicle Fuels in General Aviation Aircrafts}, series = {MTZ worldwide. 72 (2011), H. 1}, journal = {MTZ worldwide. 72 (2011), H. 1}, publisher = {Springer Automotive Media}, address = {Wiesbaden}, pages = {38 -- 43}, year = {2011}, language = {en} } @article{ReckerBosschaertsWagemakersetal.2010, author = {Recker, Elmar and Bosschaerts, Walter and Wagemakers, Rolf and Hendrick, Patrick and Funke, Harald and B{\"o}rner, Sebastian}, title = {Experimental study of a round jet in cross-flow at low momentum ratio}, series = {15th International Symposium on Applications of Laser Techniques to Fluid Mechanics Lisbon, Portugal, 05-08 July, 2010 - 1}, journal = {15th International Symposium on Applications of Laser Techniques to Fluid Mechanics Lisbon, Portugal, 05-08 July, 2010 - 1}, pages = {1 -- 13}, year = {2010}, language = {en} } @article{BecretGrossenTrillaetal.2007, author = {B{\´e}cret, P. and Grossen, J. and Trilla, J. and Robinson, A. and Bosschaerts, W. and Funke, Harald and Hendrick, P.}, title = {Testing and numerical study of a 10 kW hydrogen micro combustor}, series = {International Workshop on Micro and Nanotechnology for Power Generation and Energy Conversion Applications <7, 2007, Freiburg, Breisgau> ; PowerMEMS ; 7}, journal = {International Workshop on Micro and Nanotechnology for Power Generation and Energy Conversion Applications <7, 2007, Freiburg, Breisgau> ; PowerMEMS ; 7}, pages = {367 -- 370}, year = {2007}, language = {en} } @article{RobinsonRoennaFunke2007, author = {Robinson, A. E. and R{\"o}nna, Uwe and Funke, Harald}, title = {Testing of a 10 kW diffusive micro-mix combustor for hydrogen-fuelled micro-scale gas turbines}, series = {International Workshop on Micro and Nanotechnology for Power Generation and Energy Conversion Applications <7, 2007, Freiburg, Breisgau> ; PowerMEMS ; 7}, journal = {International Workshop on Micro and Nanotechnology for Power Generation and Energy Conversion Applications <7, 2007, Freiburg, Breisgau> ; PowerMEMS ; 7}, pages = {225 -- 228}, year = {2007}, language = {en} } @article{FunkeBoernerFalketal.2011, author = {Funke, Harald and B{\"o}rner, Sebastian and Falk, F. and Hendrick, P.}, title = {Control system modifications and their effects on the operation of a hydrogen-fueled Auxiliary Power Unit}, series = {XX international symposium on air breathing engines 2011 : ISABE 2011, Gothenburg, Sweden, 12-16 September, 2011. Vol. 2.}, journal = {XX international symposium on air breathing engines 2011 : ISABE 2011, Gothenburg, Sweden, 12-16 September, 2011. Vol. 2.}, publisher = {American Institute of Aeronautics and Astronautics}, address = {Reston, VA}, isbn = {9781618391803}, pages = {929 -- 938}, year = {2011}, language = {en} } @article{WernerWagnerMiyamotoetal.2011, author = {Werner, Frederik and Wagner, Torsten and Miyamoto, Ko-ichiro and Yoshinobu, Tatsuo and Sch{\"o}ning, Michael Josef}, title = {High speed and high resolution chemical imaging based on a new type of OLED-LAPS set-up}, series = {Procedia Engineering. 25 (2011)}, journal = {Procedia Engineering. 25 (2011)}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {1877-7058}, pages = {346 -- 349}, year = {2011}, language = {en} } @article{FunkeRobinsonHendricketal.2010, author = {Funke, Harald and Robinson, A. E. and Hendrick, P. and Wagemakers, R.}, title = {Design and Testing of a Micromix Combustor With Recuperative Wall Cooling for a Hydrogen Fuelled µ-Scale Gas Turbine}, series = {Proceedings of the ASME Turbo Expo 2010 : presented at the 2010 ASME Turbo Expo, June 14 - 18, 2010, Glasgow, UK / sponsored by the International Gas Turbine Institute / Vol. 5: Industrial and cogeneration ; microturbines and small turbomachinery ; oil and gas applications ; wind turbine technology}, journal = {Proceedings of the ASME Turbo Expo 2010 : presented at the 2010 ASME Turbo Expo, June 14 - 18, 2010, Glasgow, UK / sponsored by the International Gas Turbine Institute / Vol. 5: Industrial and cogeneration ; microturbines and small turbomachinery ; oil and gas applications ; wind turbine technology}, publisher = {ASME}, address = {New York, NY}, isbn = {978-0-7918-4400-7}, pages = {587 -- 596}, year = {2010}, language = {en} } @article{RobinsonFunkeWagemakersetal.2009, author = {Robinson, A. E. and Funke, Harald and Wagemakers, R. and Grossen, J. and Bosschaerts, W. and Hendrick, P.}, title = {Numerical and Experimental Investigation of a Micromix Combustor for a Hydrogen Fuelled μ-Scale Gas Turbine}, series = {Proceedings of the ASME Turbo Expo 2009 : : presented at the 2009 ASME Turbo Expo, June 8 - 12, 2009, Orlando, Florida, USA / sponsored by the International Gas Turbine Institute}, journal = {Proceedings of the ASME Turbo Expo 2009 : : presented at the 2009 ASME Turbo Expo, June 8 - 12, 2009, Orlando, Florida, USA / sponsored by the International Gas Turbine Institute}, publisher = {ASME}, address = {New York, NY}, isbn = {9780791848869}, pages = {253 -- 262}, year = {2009}, language = {en} } @article{BohnFunkeGier1999, author = {Bohn, D. and Funke, Harald and Gier, J.}, title = {Temperature jet development in a cross-over channel}, series = {Third European Conference on Turbomachinery - fluid dynamics and thermodynamics : : 2 - 5 March 1999, Royal National Hotel, London, UK / organized by the Energy Transfer and Thermofluid Mechanics Group of the Institution of Mechanical Engineers (IMechE); with support and sponsorship from European Commission / Vol. B.}, journal = {Third European Conference on Turbomachinery - fluid dynamics and thermodynamics : : 2 - 5 March 1999, Royal National Hotel, London, UK / organized by the Energy Transfer and Thermofluid Mechanics Group of the Institution of Mechanical Engineers (IMechE); with support and sponsorship from European Commission / Vol. B.}, publisher = {Professional Engineering Publ.}, address = {Bury St. Edmunds}, pages = {671 -- 680}, year = {1999}, language = {en} } @article{BohnFunkeHeueretal.2000, author = {Bohn, Dieter and Funke, Harald and Heuer, Tom and B{\"u}tikofer, J.}, title = {Numerical and experimental investigations of the influence of different swirl-ratios on the temperature streak equalization in a 4-stage turbine}, series = {ASME Turbo Expo 2000 ; Munich, May 8-11 2000}, journal = {ASME Turbo Expo 2000 ; Munich, May 8-11 2000}, address = {Munich}, year = {2000}, language = {en} } @article{BohnFunkeSuerkenetal.2001, author = {Bohn, Dieter and Funke, Harald and S{\"u}rken, Norbert and Kreitmeier, F.}, title = {Numerical and experimental investigations on endwall contouring in a four-stage turbine}, series = {ASME Turbo Expo Land Sea \& Air 2001 : June 4 - 8, 2001, New Orleans, Louisiana / IGTI, International Gas Turbine Institute. American Society of Mechanical Engineers. International Gas Turbine Institute ..}, journal = {ASME Turbo Expo Land Sea \& Air 2001 : June 4 - 8, 2001, New Orleans, Louisiana / IGTI, International Gas Turbine Institute. American Society of Mechanical Engineers. International Gas Turbine Institute ..}, publisher = {ASME}, address = {New York, NY}, isbn = {0-7918-3528-6}, pages = {CD-Rom}, year = {2001}, language = {en} } @article{FunkeRoennaRobinson2008, author = {Funke, Harald and R{\"o}nna, Uwe and Robinson, A. E.}, title = {Development and testing of a 10 kW diffusive micromix combustor for hydrogen-fuelled μ-scale gas turbines}, series = {Proceedings of ASME Turbo Expo 2008: Power for Land, Sea and Air ; GT2008 ; June 9-13, 2008, Berlin, Germany}, journal = {Proceedings of ASME Turbo Expo 2008: Power for Land, Sea and Air ; GT2008 ; June 9-13, 2008, Berlin, Germany}, publisher = {ASME}, address = {New York, NY}, pages = {1 -- 8}, year = {2008}, language = {en} } @article{FunkeBoernerKrebsetal.2011, author = {Funke, Harald and B{\"o}rner, Sebastian and Krebs, W. and Wolf, E.}, title = {Experimental Characterization of Low NOx Micromix Prototype Combustors for Industrial Gas Turbine Applications}, series = {ASME Turbo Expo 2011 ; Vancouver, Canada, June 6-10, 2011}, journal = {ASME Turbo Expo 2011 ; Vancouver, Canada, June 6-10, 2011}, year = {2011}, language = {en} } @article{HartungGirodHorn1995, author = {Hartung, Frank and Girod, Bernd and Horn, Uwe}, title = {Subband Image Coding / Girod, Bernd ; Hartung, Frank ; Horn, Uwe}, series = {Subband and Wavelet Transforms: Design and Applications / ed. by Ali N. Akansu}, journal = {Subband and Wavelet Transforms: Design and Applications / ed. by Ali N. Akansu}, publisher = {Kluwer}, address = {Boston}, isbn = {0792396456}, pages = {213 -- 250}, year = {1995}, language = {en} } @article{Hartung2003, author = {Hartung, Frank}, title = {Mobile DRM Introduction: The Need for Mobile DRM}, series = {Digital Rights Management : Technological, Economic, Legal and Political Aspects / Becker, Eberhard [u.a.]}, journal = {Digital Rights Management : Technological, Economic, Legal and Political Aspects / Becker, Eberhard [u.a.]}, publisher = {Springer}, address = {Berlin}, pages = {138 -- 149}, year = {2003}, language = {en} } @article{HartungGirod1997, author = {Hartung, Frank and Girod, Bernd}, title = {Copyright protection in video delivery networks by watermarking of pre-compressed video / Hartung, Frank ; Girod, Bernd}, series = {Multimedia Applications, Services and Techniques - EMAST ´97 : Second European Conference Milan, Italy, May 21-23, 1997 Proceedings / Fdida, Serge ; Morganti, Michele}, journal = {Multimedia Applications, Services and Techniques - EMAST ´97 : Second European Conference Milan, Italy, May 21-23, 1997 Proceedings / Fdida, Serge ; Morganti, Michele}, publisher = {Springer}, address = {Berlin}, pages = {423 -- 436}, year = {1997}, language = {en} } @article{HartungRamme2000, author = {Hartung, Frank and Ramme, F.}, title = {Digital rights management and watermarking of multimedia content for m-commerce applications / Hartung, F. ; Ramme, F.}, series = {IEEE Communications Magazine. 38 (2000), H. 11}, journal = {IEEE Communications Magazine. 38 (2000), H. 11}, isbn = {0163-6804}, pages = {78 -- 84}, year = {2000}, language = {en} } @article{HartungGirod1996, author = {Hartung, Frank and Girod, Bernd}, title = {Statistical optimization of switched two-level quantizers with application to DPCM encoding of color video / Hartung, Frank ; Girod, Bernd}, series = {IEEE International Conference on Acoustics, Speech, and Signal Processing, 1996. ICASSP-96. Conference Proceedings., 1996}, journal = {IEEE International Conference on Acoustics, Speech, and Signal Processing, 1996. ICASSP-96. Conference Proceedings., 1996}, isbn = {0-7803-3192-3}, pages = {1974 -- 1977}, year = {1996}, language = {en} } @article{HartungNiebertSchiederetal.2006, author = {Hartung, Frank and Niebert, Norbert and Schieder, Andreas and Rembarz, Ren{\´e}}, title = {Advances in network-supported media delivery in next-generation mobile systems / Hartung, Frank ; Niebert, Norbert ; Schieder, Andreas ; Rembarz, Ren{\´e} ; Schmid, Stefan ; Eggert, Lars}, series = {IEEE Communications Magazine. 44 (2006), H. 8}, journal = {IEEE Communications Magazine. 44 (2006), H. 8}, isbn = {0163-6804}, pages = {82 -- 89}, year = {2006}, language = {en} } @article{HammHartung2011, author = {Hamm, Laurits and Hartung, Frank}, title = {High Quality Visual Communication based on IMS}, series = {Mobilkommunikation : Technologien und Anwendungen ; Vortr{\"a}ge der 16. ITG-Fachtagung vom 18. bis 19. Mai 2011 in Osnabr{\"u}ck / Veranst.: Informationstechnische Gesellschaft im VDE (ITG) ... Tagungsleitung: Ralf T{\"o}njes. Programmkomitee/Hrsg.: Peter Roer}, journal = {Mobilkommunikation : Technologien und Anwendungen ; Vortr{\"a}ge der 16. ITG-Fachtagung vom 18. bis 19. Mai 2011 in Osnabr{\"u}ck / Veranst.: Informationstechnische Gesellschaft im VDE (ITG) ... Tagungsleitung: Ralf T{\"o}njes. Programmkomitee/Hrsg.: Peter Roer}, publisher = {VDE-Verl.}, address = {Berlin}, isbn = {978-3-8007-3352-1}, pages = {80 -- 85}, year = {2011}, language = {en} } @article{HartungKesiciCatrein2011, author = {Hartung, Frank and Kesici, Sinan and Catrein, Daniel}, title = {DRM protected Dynamic Adaptive HTTP Streaming}, series = {Proceedings of the 2011 ACM Multimedia Systems Conference [Elektronische Ressource] : February 23 - 25, 2011, San Jose, CA, USA / sponsored by: ACM SIGMM}, journal = {Proceedings of the 2011 ACM Multimedia Systems Conference [Elektronische Ressource] : February 23 - 25, 2011, San Jose, CA, USA / sponsored by: ACM SIGMM}, publisher = {ACM}, address = {New York, NY}, isbn = {9781450305181}, pages = {277 -- 282}, year = {2011}, language = {en} } @article{KotliarKoshitzSvetlowaetal.2006, author = {Kotliar, Konstantin and Koshitz, I. N. and Svetlowa, O. V. and Zaseeva, M. V.}, title = {Physiological principles of hypotensive therapy of open-angle glaucoma during presbyopic period. Part II Promising algorithms of practical sparing applications / Koshitz, I. N. ; Svetlova, O. V. ; Zaseeva, M. V. ; Shuhaev, S. V. ; Makarov, F. N. ; Kotliar}, series = {Glaukoma (2006)}, journal = {Glaukoma (2006)}, publisher = {-}, pages = {51 -- 70}, year = {2006}, language = {en} } @article{KotliarKoshitzSvetlowaetal.2005, author = {Kotliar, Konstantin and Koshitz, I. N. and Svetlowa, O. V. and Makarov, F. N.}, title = {Biomechanical analysis of traditional and contemporary conceptions on pathogenesis of the primary open angle glaucoma / Koshitz, I. N. ; Svetlova, O. V. ; Kotliar, K. E. ; Makarov, F. N. ; Smolnikov, B. A.}, series = {Glaukoma (2005)}, journal = {Glaukoma (2005)}, publisher = {-}, pages = {41 -- 63}, year = {2005}, language = {en} } @article{KotliarSvetlovaStegaevetal.2004, author = {Kotliar, Konstantin and Svetlova, O. V. and Stegaev, V. A. and Parkhomov, S. D.}, title = {Biomechanical substantiation of relatively low efficiency of recurrent laser trabeculoplasty / Svetlova, O. V. ; Stagaev, V. A. ; Parkhomov, S. D. ; Kotliar, K. E. ; Makarov, F. N. ; Smolnikov, B. A. ; Koshitz, I. N.}, series = {Glaukoma (2004)}, journal = {Glaukoma (2004)}, publisher = {-}, pages = {29 -- 39}, year = {2004}, language = {en} } @article{KotliarSvetlovaSourjikovetal.2004, author = {Kotliar, Konstantin and Svetlova, O. V. and Sourjikov, A. V. and Zaseeva, M. V.}, title = {Biomechanical peculiarities of aqueous humor production system and outflow regulation system / Svetlova, O. V. ; Sourjikov, A. V. ; Kotliar, K. E. ; Zaseeva, M. V. ; Shukhaev, S. V. ; Koshitz, I. N.}, series = {Glaukoma (2004)}, journal = {Glaukoma (2004)}, publisher = {-}, pages = {66 -- 76}, year = {2004}, language = {en} } @article{MiyamotoKanekoMatsuoetal.2012, author = {Miyamoto, Ko-ichiro and Kaneko, Kazumi and Matsuo, Akira and Wagner, Torsten and Kanoh, Shin{\´i}chiro and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo}, title = {Miniaturized chemical imaging sensor system using an OLED display panel}, series = {Sensors and Actuators B: Chemical}, volume = {170}, journal = {Sensors and Actuators B: Chemical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2011.02.029}, pages = {82 -- 87}, year = {2012}, abstract = {The chemical imaging sensor is a semiconductor-based chemical sensor that can visualize the two-dimensional distribution of specific ions or molecules in the solution. In this study, we developed a miniaturized chemical imaging sensor system with an OLED display panel as a light source that scans the sensor plate. In the proposed configuration, the display panel is placed directly below the sensor plate and illuminates the back surface. The measured area defined by illumination can be arbitrarily customized to fit the size and the shape of the sample to be measured. The waveform of the generated photocurrent, the current-voltage characteristics and the pH sensitivity were investigated and pH imaging with this miniaturized system was demonstrated.}, language = {en} } @article{KirchnerOberlaenderFriedrichetal.2012, author = {Kirchner, Patrick and Oberl{\"a}nder, Jan and Friedrich, Peter and Berger, J{\"o}rg and Rysstad, Gunnar and Sch{\"o}ning, Michael Josef and Keusgen, Michael}, title = {Realisation of a calorimetric gas sensor on polyimide foil for applications in aseptic food industry}, series = {Sensors and Actuators B: Chemical}, volume = {170}, journal = {Sensors and Actuators B: Chemical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2011.01.032}, pages = {60 -- 66}, year = {2012}, abstract = {A calorimetric gas sensor is presented for the monitoring of vapour-phase H2O2 at elevated temperature during sterilisation processes in aseptic food industry. The sensor was built up on a flexible polyimide foil (thickness: 25 μm) that has been chosen due to its thermal stability and low thermal conductivity. The sensor set-up consists of two temperature-sensitive platinum thin-film resistances passivated by a layer of SU-8 photo resist and catalytically activated by manganese(IV) oxide. Instead of an active heating structure, the calorimetric sensor utilises the elevated temperature of the evaporated H2O2 aerosol. In an experimental test rig, the sensor has shown a sensitivity of 4.78 °C/(\%, v/v) in a H2O2 concentration range of 0\%, v/v to 8\%, v/v. Furthermore, the sensor possesses the same, unchanged sensor signal even at varied medium temperatures between 210 °C and 270 °C of the gas stream. At flow rates of the gas stream from 8 m3/h to 12 m3/h, the sensor has shown only a slightly reduced sensitivity at a low flow rate of 8 m3/h. The sensor characterisation demonstrates the suitability of the calorimetric gas sensor for monitoring the efficiency of industrial sterilisation processes.}, language = {en} } @article{AtlasBrealeyDharetal.2012, author = {Atlas, Glen and Brealey, David and Dhar, Sunil and Dikta, Gerhard and Singer, Meryvn}, title = {Additional hemodynamic measurements with an esophageal Doppler monitor: a preliminary report of compliance, force, kinetic energy, and afterload in the clinical setting}, series = {Journal of clinical monitoring and computing}, journal = {Journal of clinical monitoring and computing}, number = {26}, publisher = {Springer Nature}, address = {London}, isbn = {1573-2614}, doi = {10.1007/s10877-012-9386-5}, pages = {473 -- 482}, year = {2012}, abstract = {The esophageal Doppler monitor (EDM) is a minimally-invasive hemodynamic device which evaluates both cardiac output (CO), and fluid status, by estimating stroke volume (SV) and calculating heart rate (HR). The measurement of these parameters is based upon a continuous and accurate approximation of distal thoracic aortic blood flow. Furthermore, the peak velocity (PV) and mean acceleration (MA), of aortic blood flow at this anatomic location, are also determined by the EDM. The purpose of this preliminary report is to examine additional clinical hemodynamic calculations of: compliance (C), kinetic energy (KE), force (F), and afterload (TSVRi). These data were derived using both velocity-based measurements, provided by the EDM, as well as other contemporaneous physiologic parameters. Data were obtained from anesthetized patients undergoing surgery or who were in a critical care unit. A graphical inspection of these measurements is presented and discussed with respect to each patient's clinical situation. When normalized to each of their initial values, F and KE both consistently demonstrated more discriminative power than either PV or MA. The EDM offers additional applications for hemodynamic monitoring. Further research regarding the accuracy, utility, and limitations of these parameters is therefore indicated.}, language = {en} } @book{Artmann2011, author = {Artmann, Gerhard}, title = {Stem cell engineering : principles and applications / Gerhard M. Artmann ... eds.}, publisher = {Springer}, address = {Berlin [u.a.]}, isbn = {978-3-642-11864-7}, pages = {XLI, 541 S. : Ill., graph. Darst.}, year = {2011}, language = {en} } @article{IkenKirsanovLeginetal.2012, author = {Iken, Heiko and Kirsanov, D. and Legin, A. and Sch{\"o}ning, Michael Josef}, title = {Novel Thin-Film Polymeric Materials for the Detection of Heavy Metals}, series = {Procedia Engineering}, journal = {Procedia Engineering}, number = {47}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2012.09.148}, pages = {322 -- 325}, year = {2012}, abstract = {A variety of transition metals, e.g., copper, zinc, cadmium, lead, etc. are widely used in industry as components for wires, coatings, alloys, batteries, paints and so on. The inevitable presence of transition metals in industrial processes implies the ambition of developing a proper analytical technique for their adequate monitoring. Most of these elements, especially lead and cadmium, are acutely toxic for biological organisms. Quantitative determination of these metals at low activity levels in different environmental and industrial samples is therefore a vital task. A promising approach to achieve an at-side or on-line monitoring on a miniaturized and cost efficient way is the combination of a common potentiometric sensor array with heavy metal-sensitive thin-film materials, like chalcogenide glasses and polymeric materials, respectively.}, language = {en} } @article{MiyamotoIchimuraWagneretal.2012, author = {Miyamoto, K. and Ichimura, H. and Wagner, Torsten and Yoshinobu, T. and Sch{\"o}ning, Michael Josef}, title = {Chemical Imaging of ion Diffusion in a Microfluidic Channel}, series = {Procedia Engineering}, journal = {Procedia Engineering}, number = {47}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2012.09.289}, pages = {886 -- 889}, year = {2012}, abstract = {The chemical imaging sensor is a chemical sensor which is capable of visualizing the spatial distribution of chemical species in sample solution. In this study, a novel measurement system based on the chemical imaging sensor was developed to observe the inside of a Y-shaped microfluidic channel while injecting two sample solutions from two branches. From the collected chemical images, it was clearly observed that the injected solutions formed laminar flows in the microfluidic channel. In addition, ion diffusion across the laminar flows was observed. This label-free method can acquire quantitative data of ion distribution and diffusion in microfluidic devices, which can be used to determine the diffusion coefficients, and therefore, the molecular weights of chemical species in the sample solution.}, language = {en} } @article{WagnerShigiaharaMiyamotoetal.2012, author = {Wagner, Torsten and Shigiahara, N. and Miyamoto, K. and Suzurikawa, J. and Finger, F. and Sch{\"o}ning, Michael Josef and Yoshinobu, T.}, title = {Light-addressable Potentiometric Sensors and Light-addressable Electrodes as a Combined Sensor-and-manipulator Microsystem with High Flexibility}, series = {Procedia Engineering}, journal = {Procedia Engineering}, number = {47}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2012.09.290}, pages = {890 -- 893}, year = {2012}, abstract = {This work describes the novel combination of the light-addressable electrode (LAE) and the light-addressable potentiometric sensor (LAPS) into a microsystem set-up. Both the LAE as well as the LAPS shares the principle of addressing the active spot by means of a light beam. This enables both systems to manipulate resp. to detect an analyte with a high spatial resolution. Hence, combining both principles into a single set-up enables the active stimulation e.g., by means of electrolysis and a simultaneous observation e.g., the response of an entrapped biological cell by detection of extracellular pH changes. The work will describe the principles of both technologies and the necessary steps to integrate them into a single set-up. Furthermore, examples of application and operation of such systems will be presented.}, language = {en} } @article{Pieper2009, author = {Pieper, Martin}, title = {Vector hyperinterpolation on the sphere}, series = {Journal of approximation theory. 156 (2009), H. 2}, journal = {Journal of approximation theory. 156 (2009), H. 2}, isbn = {0021-9045}, pages = {173 -- 186}, year = {2009}, language = {en} } @article{MuribTranCeunincketal.2012, author = {Murib, Mohammed S. and Tran, Anh Quang and Ceuninck, Ward de and Sch{\"o}ning, Michael Josef and Nesladek, Milos and Serpeng{\"u}zel, Ali and Wagner, Patrick}, title = {Analysis of an optical biosensor based on elastic light scattering from diamond-, glass-, and sapphire microspheres}, series = {Physica Status Solidi A}, volume = {209}, journal = {Physica Status Solidi A}, number = {9}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201100795}, pages = {1804 -- 1810}, year = {2012}, abstract = {Deoxyribonucleic acid (DNA) and protein recognition are now standard tools in biology. In addition, the special optical properties of microsphere resonators expressed by the high quality factor (Q-factor) of whispering gallery modes (WGMs) or morphology dependent resonances (MDRs) have attracted the attention of the biophotonic community. Microsphere-based biosensors are considered as powerful candidates to achieve label-free recognition of single molecules due to the high sensitivity of their WGMs. When the microsphere surface is modified with biomolecules, the effective refractive index and the effective size of the microsphere change resulting in a resonant wavelength shift. The transverse electric (TE) and the transverse magnetic (TM) elastic light scattering intensity of electromagnetic waves at 600 and 1400 nm are numerically calculated for DNA and unspecific binding of proteins to the microsphere surface. The effect of changing the optical properties was studied for diamond (refractive index 2.34), glass (refractive index 1.50), and sapphire (refractive index 1.75) microspheres with a 50 µm radius. The mode spacing, the linewidth of WGMs, and the shift of resonant wavelength due to the change in radius and refractive index, were analyzed by numerical simulations. Preliminary results of unspecific binding of biomolecules are presented. The calculated shift in WGMs can be used for biomolecules detection.}, language = {en} } @inproceedings{LogenHoefkenSchuba2012, author = {Logen, Steffen and H{\"o}fken, Hans and Schuba, Marko}, title = {Simplifying RAM Forensics : A GUI and Extensions for the Volatility Framework}, series = {2012 Seventh International Conference on Availability, Reliability and Security (ARES), 20-24 August 2012, Prague, Czech Republic}, booktitle = {2012 Seventh International Conference on Availability, Reliability and Security (ARES), 20-24 August 2012, Prague, Czech Republic}, publisher = {IEEE}, address = {New York}, isbn = {978-1-4673-2244-7}, doi = {10.1109/ARES.2012.12}, pages = {620 -- 624}, year = {2012}, abstract = {The Volatility Framework is a collection of tools for the analysis of computer RAM. The framework offers a multitude of analysis options and is used by many investigators worldwide. Volatility currently comes with a command line interface only, which might be a hinderer for some investigators to use the tool. In this paper we present a GUI and extensions for the Volatility Framework, which on the one hand simplify the usage of the tool and on the other hand offer additional functionality like storage of results in a database, shortcuts for long Volatility Framework command sequences, and entirely new commands based on correlation of data stored in the database.}, language = {en} } @article{BohrnStuetzFleischeretal.2013, author = {Bohrn, Ulrich and St{\"u}tz, Evamaria and Fleischer, Maximilian and Sch{\"o}ning, Michael Josef and Wagner, Patrick}, title = {Using a cell-based gas biosensor for investigation of adverse effects of acetone vapors in vitro}, series = {Biosensors and Bioelectronics. 40 (2013), H. 1}, journal = {Biosensors and Bioelectronics. 40 (2013), H. 1}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {0956-5663}, pages = {393 -- 400}, year = {2013}, language = {en} } @phdthesis{Kotliar2008, author = {Kotliar, Konstantin}, title = {Functional in-vivo assessment and biofluidmechanical analysis of age-related and pathological microstructural changes in retinal vessels [Elektronische Ressource]}, publisher = {-}, year = {2008}, language = {en} } @book{Grotendorst2012, author = {Grotendorst, Johannes}, title = {Hierarchical methods for dynamics in complex molecular systems : IAS Winter School, 5 - 9 March 2012, Forschungszentrum J{\"u}lich GmbH ; lecture notes / ed. by Johannes Grotendorst, Godehard Sutmann, Gerhard Gompper, Dominik Marx}, publisher = {Forschungszentrum J{\"u}lich}, address = {J{\"u}lich}, isbn = {978-3-89336-768-9}, pages = {VI, 540 S. zahlr. Ill. u. graph. Darst.}, year = {2012}, language = {en} } @article{GutheilBergGrotendorst2012, author = {Gutheil, Inge and Berg, Tommy and Grotendorst, Johannes}, title = {Performance Analysis of Parallel Eigensolvers of two Libraries on BlueGene/P}, series = {Journal of Mathematics and Systems Science}, volume = {2}, journal = {Journal of Mathematics and Systems Science}, number = {4}, publisher = {David Publishing}, address = {Libertyville}, issn = {2159-5291}, doi = {10.17265/2159-5291/2012.04.003}, pages = {231 -- 236}, year = {2012}, abstract = {Many applications in computational science and engineering require the computation of eigenvalues and vectors of dense symmetric or Hermitian matrices. For example, in DFT (density functional theory) calculations on modern supercomputers 10\% to 30\% of the eigenvalues and eigenvectors of huge dense matrices have to be calculated. Therefore, performance and parallel scaling of the used eigensolvers is of upmost interest. In this article different routines of the linear algebra packages ScaLAPACK and Elemental for parallel solution of the symmetric eigenvalue problem are compared concerning their performance on the BlueGene/P supercomputer. Parameters for performance optimization are adjusted for the different data distribution methods used in the two libraries. It is found that for all test cases the new library Elemental which uses a two-dimensional element by element distribution of the matrices to the processors shows better performance than the old ScaLAPACK library which uses a block-cyclic distribution.}, language = {en} } @article{Grotendorst2012, author = {Grotendorst, Johannes}, title = {IAS Winter School: Hierarchical Methods for Dynamics in Complex Molecular Systems}, series = {Innovatives Supercomputing in Deutschland : inSiDE. 10 (2012), H. 1}, journal = {Innovatives Supercomputing in Deutschland : inSiDE. 10 (2012), H. 1}, publisher = {-}, pages = {104}, year = {2012}, language = {en} } @inproceedings{UibelBlass2007, author = {Uibel, Thomas and Blaß, Hans Joachim}, title = {Edge Joints with Dowel Type Fasteners in Cross Laminated Timber}, series = {Proceedings. CIB-W18 Meeting 2007, Bled, Slovenia 2007}, booktitle = {Proceedings. CIB-W18 Meeting 2007, Bled, Slovenia 2007}, issn = {0945-6996}, pages = {1 -- 11}, year = {2007}, language = {en} } @inproceedings{UibelBlass2010, author = {Uibel, Thomas and Blaß, Hans Joachim}, title = {Determining Suitable Spacings and Distances for Self-tapping Screws by Experimental and Numerical Studies}, series = {Proceedings of the 11th World Conference on Timber Engineering, WCTE 2010 : World Conference on Timber Engineering; [June 20 - 24, 2010, Riva del Garda, Trento, Italy] . Vol. III, Riva del Garda, Italy 2010}, booktitle = {Proceedings of the 11th World Conference on Timber Engineering, WCTE 2010 : World Conference on Timber Engineering; [June 20 - 24, 2010, Riva del Garda, Trento, Italy] . Vol. III, Riva del Garda, Italy 2010}, editor = {Cecotti, A.}, pages = {669 -- 670}, year = {2010}, language = {en} } @article{HennemannKohlReisertetal.2013, author = {Hennemann, J{\"o}rg and Kohl, Claus-Dieter and Reisert, Steffen and Kirchner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Copper oxide nanofibres for detection of hydrogen peroxide vapour at high concentrations}, series = {physica status solidi (a)}, volume = {210}, journal = {physica status solidi (a)}, number = {5}, publisher = {Wiley}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201200775}, pages = {859 -- 863}, year = {2013}, abstract = {We present a sensor concept based on copper(II)oxide (CuO) nanofibres for the detection of hydrogen peroxide (H2O2) vapour in the percent per volume (\% v/v) range. The fibres were produced by using the electrospinning technique. To avoid water condensation in the pores, the fibres were initially modified by an exposure to H2S to get an enclosed surface. By a thermal treatment at 350 °C the fibres were oxidised back to CuO. Thereby, the visible pores disappear which was verified by SEM analysis. The fibres show a decrease of resistance with increasing H2O2 concentration which is due to the fact that hydrogen peroxide is an oxidising gas and CuO a p-type semiconductor. The sensor shows a change of resistance within the minute range to the exposure until the maximum concentration of 6.9\% v/v H2O2. At operating temperatures below 450 °C the corresponding sensor response to a concentration of 4.1\% v/v increases. The sensor shows a good reproducibility of the signal at different measurements. CuO seems to be a suitable candidate for the detection of H2O2 vapour at high concentrations. Resistance behaviour of the sensor under exposure to H2O2 vapours between 2.3 and 6.9\% v/v at an operating temperature of 450 °C.}, language = {en} } @article{ReisertSchneiderGeissleretal.2013, author = {Reisert, Steffen and Schneider, Benno and Geissler, Hanno and Gompel, Matthias van and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Multi-sensor chip for the investigation of different types of metal oxides for the detection of H2O2 in the ppm range}, series = {physica status solidi (a)}, volume = {210}, journal = {physica status solidi (a)}, number = {5}, publisher = {Wiley}, address = {Weinheim}, issn = {1862-6319}, pages = {898 -- 904}, year = {2013}, abstract = {In this work, a multi-sensor chip for the investigation of the sensing properties of different types of metal oxides towards hydrogen peroxide in the ppm range is presented. The fabrication process and physical characterization of the multi-sensor chip are described. Pure SnO2 and WO3 as well as Pd- and Pt-doped SnO2 films are characterized in terms of their sensitivity to H2O2. The sensing films have been prepared by drop-coating of water-dispensed nano-powders. A physical characterization, including scanning electron microscopy and X-ray diffraction analysis of the deposited metal-oxide films, was done. From the measurements in hydrogen peroxide atmosphere, it could be shown, that all of the tested metal oxide films are suitable for the detection of H2O2 in the ppm range. The highest sensitivity and reproducibility was achieved using Pt-doped SnO2. Calibration plot of a SnO2, WO3, Pt-, and Pd-doped SnO2 gas sensor for H2O2 concentrations in the ppm range.}, language = {en} } @article{KotliarHanssenEberhardtetal.2013, author = {Kotliar, Konstantin and Hanssen, Henner and Eberhardt, Karla and Vilser, Walthard and Schmaderer, Christoph and Halle, Martin and Heemann, Uwe and Baumann, M.}, title = {Retinal pulse wave velocity in young male normotensive and mildly hypertensive subjects}, series = {Microcirculation}, journal = {Microcirculation}, publisher = {Wiley}, address = {Malden}, issn = {1549-8719}, year = {2013}, language = {en} } @article{FeuchtSchoenbachLanzletal.2013, author = {Feucht, Nikolaus and Sch{\"o}nbach, Etienne Michael and Lanzl, Ines and Kotliar, Konstantin and Lohmann, Chris Patrick and Maier, Mathias}, title = {Changes in the foveal microstructure after intravitreal bevacizumab application in patients with retinal vascular disease}, series = {Clinical Ophthalmology}, volume = {7}, journal = {Clinical Ophthalmology}, publisher = {Dove Medical Press}, address = {Auckland, New Zealand}, issn = {1177-5483}, pages = {173 -- 178}, year = {2013}, language = {en} } @article{HeinzelSchaeferMuelleretal.2010, author = {Heinzel, Alexander and Sch{\"a}fer, Ralf and M{\"u}ller, Hans-Wilhelm and Schieffer, Andre and Ingenhag, Ariane and Eickhoff, Simon B. and Northoff, Georg and Franz, Matthias and Hautzel, Hubertus}, title = {Increased Activation of the Supragenual Anterior Cingulate Cortex during Visual Emotional Processing in Male Subjects with High Degrees of Alexithymia: An Event-Related fMRI Study}, series = {Psychotherapy and Psychosomatics}, volume = {79}, journal = {Psychotherapy and Psychosomatics}, number = {6}, publisher = {Karger}, address = {Basel}, issn = {0033-3190}, doi = {10.1159/000320121}, pages = {363 -- 370}, year = {2010}, abstract = {Background: One of the most prominent neurobiological models of alexithymia assumes an altered function of the anterior cingulate cortex (ACC) as the crucial neural correlate of alexithymia. So far functional imaging studies have yielded inconclusive results. Therefore, we tested this hypothesis in healthy alexithymics and nonalexithymics in an event-related fMRI study. Methods: Thirty high- and 30 low-alexithymic right-handed male subjects (selected by the 20-item Toronto Alexithymia Scale, TAS-20) were investigated with event-related fMRI using a picture viewing paradigm. The stimuli consisted of happy, fearful and neutral facial expressions (Ekman-Friesen) as well as positive, negative and neutral pictures from the International Affective Picture System. Results: Contrasting the high-alexithymic with the low-alexithymic group we observed increased activation of the supragenual ACC for different emotional valences as well as for different emotional stimuli. Moreover, there was a positive correlation of the ACC with the individual TAS-20 scores but no correlations with the individual Beck Depression Inventory scores. Additionally, there was no difference in activity of the amygdala. Conclusions: We demonstrated that the supragenual ACC is constantly activated more strongly in alexithymic subjects and that this activation is related to the symptoms of alexithymia and not to associated symptoms such as depression. Therefore, our findings support the hypothesis of an altered function of the ACC in alexithymia.}, language = {en} } @article{HeinzelSchaeferMuelleretal.2010, author = {Heinzel, Alexander and Sch{\"a}fer, Ralf and M{\"u}ller, Hans-Wilhelm and Schieffer, Andre and Ingenhag, Ariane and Northoff, Georg and Franz, Matthias and Hautzel, Hubertus}, title = {Differential modulation of valence and arousal in high-alexithymic and low-alexithymic individuals}, series = {Neuroreport}, volume = {21}, journal = {Neuroreport}, number = {15}, publisher = {Lippincott Williams \& Wilkins}, address = {London}, issn = {1473-558X}, doi = {10.1097/WNR.0b013e32833f38e0}, pages = {998 -- 1002}, year = {2010}, abstract = {High-alexithymic individuals are characterized by an impaired ability to identify and communicate emotions whereas low-alexithymic individuals have a wide-ranging ability to deal with emotions. This study examined the hypothesis that valence and arousal modifications of emotional stimuli differentially modulate cortical regions in high-alexithymic and low-alexithymic individuals. To this end, 28 high-alexithymic and 25 low-alexithymic individuals were investigated with event-related fMRI using visual emotional stimuli. We found differential neural activations in the dorsal anterior cingulate, the insula and the amygdala. We suggest that these differences may account for the impaired ability of high-alexithymic individuals to appropriately handle emotional stimuli.}, language = {en} } @article{NomdedeuWillenSchiefferetal.2012, author = {Nomdedeu, Mar Monsonis and Willen, Christine and Schieffer, Andre and Arndt, Hartmut}, title = {Temperature-dependent ranges of coexistence in a model of a two-prey-one-predator microbial food web}, series = {Marine Biology}, volume = {159}, journal = {Marine Biology}, number = {11}, publisher = {Springer}, address = {Berlin}, issn = {1432-1793}, doi = {10.1007/s00227-012-1966-x}, pages = {2423 -- 2430}, year = {2012}, abstract = {The objective of our study was to analyze the effects of temperature on the population dynamics of a three-species food web consisting of two prey bacteria (Pedobacter sp. and Acinetobacter johnsonii) and a protozoan predator (Tetrahymena pyriformis) as model organisms. We assessed the effects of temperature on the growth rates of all three species with the objective of developing a model with four differential equations based on the experimental data. The following hypotheses were tested at a theoretical level: Firstly, temperature changes can affect the dynamic behavior of a system by temperature-dependent parameters and interactions and secondly, food web response to temperature cannot be derived from the single species temperature response. The main outcome of the study is that temperature changes affect the parameter range where coexistence is possible within all three species. This has significant consequences on our ideas regarding the evaluation of effects of global warming.}, language = {en} } @phdthesis{Schieffer2012, author = {Schieffer, Andre}, title = {Studies on diversity and coexistence in an experimental microbial community}, pages = {76 Bl. : Ill.}, year = {2012}, abstract = {Biodiversity and the coexistence of species have puzzled and fascinated biologists since decades and is a hotspot in todays' natural sciences. Preserving this biodiversity is a great challenge as habitats and environments underlying tremendous changes like climate change and the loss of natural habitats, which are mainly due to anthropogenic influences. The coexistence of numerous species even in homogeneous environments is a stunning feature of natural communities and has been summarized under the term 'paradox of plankton'. Up to now, there are several mechanisms discussed, which may contribute to local and global diversity of organisms. Several interspecific trade offs have been identified maintaining the coexistence of species like their abilities regarding competition and predator avoidance, their capability to disperse in space and time, and their ability to exploit variable resources. Further, micro-evolutionary dynamics supporting the coexistence of species have been added to our knowledge, and deriving from theoretical deterministic models, non-linear dynamics which describe the temporal fluctuation of abundances of organisms. Whereas competition and predation seem to be clue structural elements within interacting organisms, the intrinsic dynamic behavior - by means of temporal changes in abundance - plays an important role regarding coexistence within a community. The present work sheds light on different factors affecting the coexistence of species using experimental microbial model systems consisting of a bacterivorous ciliate as the predator and two bacteria strains as prey organism. Additionally, another experimental setup consisting of two up to five bacteria species competing for one limiting resource was investigated. Highly controllable chemostat systems were established to exclude extrinsic disturbances. According to theoretical analyses I was able to show - experimentally and theoretically - that phenotypic plasticity of one species within a microbial one-predator-two-prey food web enlarges the range of possible coexistence of all species under different dynamic conditions, compared to a food web without phenotypic plasticity. This was accompanied by non-linear (chaotic) population dynamics within all experimental systems showing phenotypic plasticity. The experiments on the interplay of competition, predation and invasion showed that all aspects have an influence on species coexistence. Under undisturbed controlled conditions all aspects were analyzed in detail and in combination. Populations showed oscillations which were shown by quasi-chaotic attractors in phase space diagrams. Competition experiments with two up to five bacteria species competing for one limiting resource showed that all organisms were able to coexist which was mediated by species oscillations entering a regime of chaos. Besides that fact it was found, that the productivity (biomass) as well as the total cell numbers - under the same nutrition supply - increased by an increasing number of species in the experimental systems. Up to now, the occurrence of non-linear dynamics in well controlled experimental studies has been recognized several times and this phenomenon seemed to be more common in natural systems than generally assumed.}, language = {en} } @inproceedings{UibelBlass2006, author = {Uibel, Thomas and Blaß, Hans Joachim}, title = {Load Carrying Capacity of Joints with Dowel Type Fasteners in Solid Wood Panels}, series = {Proceedings. CIB-W18 Meeting 2006, Florence, Italy 2006}, booktitle = {Proceedings. CIB-W18 Meeting 2006, Florence, Italy 2006}, issn = {0945-6996}, pages = {1 -- 10}, year = {2006}, language = {en} } @article{MossetDevroedeKriegueretal.2006, author = {Mosset, J.-B. and Devroede, O. and Krieguer, M. and Rey, M. and Vieira, J.-M. and Jung, J. H. and Kuntner, C. and Streun, M. and Ziemons, Karl and Auffray, E. and Sempere-Roldan, P. and Lecoq, P. and Bruyndonckx, P. and Loude, J.-F. and Tavernier, S. and Morcel, C.}, title = {Development of an optimized LSO/LuYAP phoswich detector head for the Lausanne ClearPET demonstrator}, series = {IEEE Transactions on Nuclear Science}, volume = {53}, journal = {IEEE Transactions on Nuclear Science}, number = {1}, isbn = {0018-9499}, pages = {25 -- 29}, year = {2006}, abstract = {This paper describes the LSO/LuYAP phoswich detector head developed for the ClearPET small animal PET scanner demonstrator that is under construction in Lausanne within the Crystal Clear Collaboration. The detector head consists of a dual layer of 8×8 LSO and LuYAP crystal arrays coupled to a multi-anode photomultiplier tube (Hamamatsu R7600-M64). Equalistion of the LSO/LuYAP light collection is obtained through partial attenuation of the LSO scintillation light using a thin aluminum deposit of 20-35 nm on LSO and appropriate temperature regulation of the phoswich head between 30°C to 60°C. At 511keV, typical FWHM energy resolutions of the pixels of a phoswich head amounts to (28±2)\% for LSO and (25±2)\% for LuYAP. The LSO versus LuYAP crystal identification efficiency is better than 98\%. Six detector modules have been mounted on a rotating gantry. Axial and tangential spatial resolutions were measured up to 4 cm from the scanner axis and compared to Monte Carlo simulations using GATE. FWHM spatial resolution ranges from 1.3 mm on axis to 2.6 mm at 4 cm from the axis.}, language = {en} } @article{StreunBeerHombachetal.2008, author = {Streun, M. and Beer, S. and Hombach, T. and Jahnke, S. and Khodaverdi, M. and Larue, H. and Minwuyelet, S. and Parl, C. and Roeb, G. and Schurr, U. and Ziemons, Karl}, title = {PlanTIS: A positron emission tomograph for imaging 11C transport in plants}, series = {2007 IEEE Nuclear Science Symposium Conference Record, Vol. 6}, journal = {2007 IEEE Nuclear Science Symposium Conference Record, Vol. 6}, isbn = {1082-3654}, pages = {4110 -- 4112}, year = {2008}, abstract = {Plant growth and transport processes are highly dynamic. They are characterized by plant-internal control processes and by strong interactions with the spatially and temporally varying environment. Analysis of structure- function relations of growth and transport in plants will strongly benefit from the development of non-invasive techniques. PlanTIS (Plant Tomographic Imaging System) is designed for non-destructive 3D-imaging of positron emitting radiotracers. It will permit functional analysis of the dynamics of carbon distribution in plants including bulky organs. It will be applicable for screening transport properties of plants to evaluate e.g. temperature adaptation of genetically modified plants. PlanTIS is a PET scanner dedicated to monitor the dynamics of the 11C distribution within a plant while or after assimilation of 11CO2. Front end electronics and data acquisition architecture of the scanner are based on the ClearPETTM system [1]. Four detector modules form one of two opposing detector blocks. Optionally, a hardware coincidence detection between the blocks can be applied. In general the scan duration is rather long (~ 1 hour) compared to the decay time of 11C (20 min). As a result the count rates can vary over a wide range and accurate dead time correction is necessary.}, language = {en} } @article{ZiemonsBruyndonckxPerezetal.2008, author = {Ziemons, Karl and Bruyndonckx, P. and Perez, J. M. and Pietrzyk, U. and Rato, P. and Tavernier, S.}, title = {Beyond ClearPET: Next Aims}, series = {5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro Symposium Proceedings ISBI 2008}, journal = {5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro Symposium Proceedings ISBI 2008}, isbn = {978-1-4244-2003-2}, pages = {1421 -- 1424}, year = {2008}, abstract = {The CRYSTAL CLEAR collaboration, in short CCC, is a consortium of 12 academic institutions, mainly from Europe, joining efforts in the area of developing instrumentation for nuclear medicine and medical imaging. In the framework of the CCC a high performance small animal PET system, called ClearPET, was developed by using new technologies in electronics and crystals in a phoswich arrangement combining two types of lutetium- based scintillator materials: LSO:Ce and LuYAP:Ce. Our next aim will be the development of hybrid image systems. Hybrid MR-PET imaging has many unique advantages for brain research. This has sparked a new research line within CCC for the development of novel MR-PET compatible technologies. MRI is not as sensitive as PET but PET has poorer spatial resolution than MRI. Two major advantages of PET are sensitivity and its ability to acquire metabolic information. To assess these innovations, the development of a 9.4T hybrid animal MR-PET scanner is proposed based on an existing 9.4T MR scanner that will be adapted to enable simultaneous acquisition of MR and PET data using cutting- edge technology for both MR and PET.}, language = {en} } @article{JahnkeMenzelDusschotenetal.2009, author = {Jahnke, Siegfried and Menzel, Marion I. and Dusschoten, Dagmar van and Roeb, Gerhard W. and B{\"u}hler, Jonas and Minwuyelet, Senay and Bl{\"u}mler, Peter and Temperton, Vicky M. and Hombach, Thomas and Streun, Matthias and Beer, Simone and Khodaverdi, Maryam and Ziemons, Karl and Coenen, Heinz H. and Schurr, Ulrich}, title = {Combined MRI-PET dissects dynamic changes in plant structures and functions}, series = {The Plant Journal}, volume = {59}, journal = {The Plant Journal}, number = {4}, publisher = {Wiley}, address = {Weinheim}, isbn = {1365-313X}, pages = {634 -- 644}, year = {2009}, abstract = {Unravelling the factors determining the allocation of carbon to various plant organs is one of the great challenges of modern plant biology. Studying allocation under close to natural conditions requires non-invasive methods, which are now becoming available for measuring plants on a par with those developed for humans. By combining magnetic resonance imaging (MRI) and positron emission tomography (PET), we investigated three contrasting root/shoot systems growing in sand or soil, with respect to their structures, transport routes and the translocation dynamics of recently fixed photoassimilates labelled with the short-lived radioactive carbon isotope 11C. Storage organs of sugar beet (Beta vulgaris) and radish plants (Raphanus sativus) were assessed using MRI, providing images of the internal structures of the organs with high spatial resolution, and while species-specific transport sectoralities, properties of assimilate allocation and unloading characteristics were measured using PET. Growth and carbon allocation within complex root systems were monitored in maize plants (Zea mays), and the results may be used to identify factors affecting root growth in natural substrates or in competition with roots of other plants. MRI-PET co-registration opens the door for non-invasive analysis of plant structures and transport processes that may change in response to genomic, developmental or environmental challenges. It is our aim to make the methods applicable for quantitative analyses of plant traits in phenotyping as well as in understanding the dynamics of key processes that are essential to plant performance.}, language = {en} } @article{WedrowskiBruyndonckxTavernieretal.2009, author = {Wedrowski, M. and Bruyndonckx, P. and Tavernier, S. and Zhi, L. and Dang, J. and Mendes, P. R. and Perez, J. M. and Ziemons, Karl}, title = {Robustness of neural networks algorithm for gamma detection in monolithic block detector, positron emission tomography}, series = {2009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC)}, journal = {2009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC)}, isbn = {1082-3654}, pages = {2625 -- 2628}, year = {2009}, abstract = {The monolithic scintillator block approach for gamma detection in the Positron Emission Tomography (PET) avoids estimating Depth of Interaction (DOI), reduces dead zones in detector and diminishes costs of detector production. Neural Networks (NN) are very efficient to determine the entrance point of a gamma incident on a scintillator block. This paper presents results on the robustness of the spatial resolution as a function of the random fraction in the data, temperature and HV fluctuations. This is important when implementing the method in a real scanner. Measurements were done with two Hamamatsu S8550 APD arrays, glued on a 20 {\~A}— 20 {\~A}— 10 mm3 monolithic LSO crystal block.}, language = {en} } @article{StreunLarueParletal.2009, author = {Streun, M. and Larue, H. and Parl, C. and Ziemons, Karl}, title = {A compact PET detector readout using charge-to-time conversion}, series = {2009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC)}, journal = {2009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC)}, publisher = {IEEE}, address = {New York}, isbn = {1082-3654}, pages = {1868 -- 1870}, year = {2009}, abstract = {The readout of gamma detectors is considerably simplified when the event intensity is encoded as a pulse width (Pulse Width Modulation, PWM). Time-to-Digital-Converters (TDC) replace the conventional ADCs and multiple TDCs can be realized easily in one PLD chip (Programmable Logic Device). The output of a PWM stage is only one digital signal per channel which is well suited for transport so that further processing can be performed apart from the detector. This is particularly interesting for large systems with high channel density (e.g. high resolution scanners). In this work we present a circuit with a linear transfer function that requires a minimum of components by performing the PWM already in the preamp stage. This allows a very compact and also cost-efficient implementation of the front-end electronics.}, language = {en} } @article{StreunBrandenburgLarueetal.2001, author = {Streun, M. and Brandenburg, G. and Larue, H. and Zimmermann, E. and Ziemons, Karl and Halling, H.}, title = {Pulse recording by free-running sampling}, series = {IEEE Transactions on Nuclear Science}, volume = {48}, journal = {IEEE Transactions on Nuclear Science}, number = {3}, isbn = {0018-9499}, pages = {524 -- 526}, year = {2001}, abstract = {Pulses from a position-sensitive photomultiplier (PS-PMT) are recorded by free-running ADCs at a sampling rate of 40 MHz. A four-channel acquisition board has been developed which is equipped with four 12-bit ADCs connected to one field programmable gate array (FPGA). The FPGA manages data acquisition and the transfer to the host computer. It can also work as a digital trigger, so a separate hardware trigger can be omitted. The method of free-running sampling provides a maximum of information, besides the pulse charge and amplitude also pulse shape and starting time are contained in the sampled data. This information is crucial for many tasks such as distinguishing between different scintillator materials, determination of radiation type, pile-up recovery, coincidence detection or time-of-flight applications. The absence of an analog integrator allows very high count rates to be dealt with. Since this method is to be employed in positron emission tomography (PET), the position of an event is also important. The simultaneous readout of four channels allows localization by means of center-of-gravity weighting. First results from a test setup with LSO scintillators coupled to the PS-PMT are presented here}, language = {en} } @article{HeinrichBlumBussmannetal.2002, author = {Heinrich, U. and Blum, A. and Bussmann, N. and Engels, R. and Kemmerling, G. and Weber, S. and Ziemons, Karl}, title = {Statistical studies on the light output and energy resolution of small LSO single crystals with different surface treatments combined with various reflector materials}, series = {Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment}, volume = {486}, journal = {Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment}, number = {1-2}, issn = {0168-9002}, pages = {60 -- 66}, year = {2002}, abstract = {The optimization of light output and energy resolution of scintillators is of special interest for the development of high resolution and high sensitivity PET. The aim of this work is to obtain statistically reliable results concerning optimal surface treatment of scintillation crystals and the selection of reflector material. For this purpose, raw, mechanically polished and etched LSO crystals (size 2×2×10 mm3) were combined with various reflector materials (Teflon tape, Teflon matrix, BaSO4) and exposed to a 22Na source. In order to ensure the statistical reliability of the results, groups of 10 LSO crystals each were measured for all combinations of surface treatment and reflector material. Using no reflector material the light output increased up to 551±35\% by mechanical polishing the surface compared to 100±5\% for raw crystals. Etching the surface increased the light output to 441±29\%. The untreated crystals had an energy resolution of 24.6±4.0\%. By mechanical polishing the surface it was possible to achieve an energy resolution of 13.2±0.8\%, by etching of 14.8±0.7\%. In combination with BaSO4 as reflector material the maximum increase of light output has been established to 932±57\% for mechanically polished and 895±61\% for etched crystals. The combination with BaSO4 also caused the best improvement of the energy resolution up to 11.6±0.2\% for mechanically polished and 12.2±0.3\% for etched crystals. Relating to the light output there was no significant statistical difference between the two surface treatments in combination with BaSO4. In contrast to this, the statistical results of the energy resolution have shown the combination of mechanical polishing and BaSO4 as the optimum.}, language = {en} } @article{StreunBrandenburgLarueetal.2002, author = {Streun, M. and Brandenburg, G. and Larue, H. and Zimmermann, E. and Ziemons, Karl and Halling, H.}, title = {A PET system with free running ADCs}, series = {Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment}, volume = {486}, journal = {Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment}, number = {1-2}, issn = {0168-9002}, pages = {18 -- 21}, year = {2002}, abstract = {A small PET system has been built up with two multichannel photomultipliers, which are attached to a matrix of 64 single LSO crystals each. The signal from each multiplier is being sampled continuously by a 12 bit ADC at a sampling frequency of 40 MHz. In case of a scintillation pulse a subsequent FPGA sends the corresponding set of samples together with the channel information and a time mark to the host computer. The data transfer is performed with a rate of 20 MB/s. On the host all necessary information is extracted from the data. The pulse energy is determined, coincident events are detected and multiple hits within one matrix can be identified. In order to achieve a narrow time window the pulse starting time is refined further than the resolution of the time mark (=25 ns) would allow. This is possible by interpolating between the pulse samples. First data obtained from this system will be presented. The system is part of developments for a much larger system and has been created to study the feasibility and performance of the technique and the hardware architecture.}, language = {en} } @article{StreunBrandenburgLarueetal.2002, author = {Streun, M. and Brandenburg, G. and Larue, H. and Zimmermann, E. and Ziemons, Karl and Halling, H.}, title = {Coincidence detection by digital processing of free-running sampled pulses}, series = {Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment}, volume = {487}, journal = {Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment}, number = {3}, isbn = {0168-9002}, pages = {530 -- 534}, year = {2002}, abstract = {Coincident events in two scintillator crystals coupled to photomultipliers (PMT) are detected by processing just the digital data of the recorded pulses. For this purpose the signals from both PMTs are continuously sampled by free-running ADCs at a sampling rate of 40 MHz. For each sampled pulse the starting time is determined by processing the pulse data. Even a fairly simple interpolating algorithm results in a FWHM of about 2 ns.}, language = {en} } @article{KhodaverdiPaulySchroderetal.2002, author = {Khodaverdi, M. and Pauly, F. and Schroder, G. and Ziemons, Karl and Sievering, R. and Halling, H.}, title = {Preliminary studies of a micro-CT for a combined small animal PET/CT scanner}, series = {2001 IEEE Nuclear Science Symposium Conference Record, Vol. 3}, journal = {2001 IEEE Nuclear Science Symposium Conference Record, Vol. 3}, issn = {1082-3654}, pages = {1605 -- 1606}, year = {2002}, abstract = {We are developing an X-ray computed tomography (CT) system which will be combined with a high resolution animal PET system. This permits acquisition of both molecular and anatomical images in a single machine. In particular the CT will also be utilized for the quantification of the animal PET data by providing accurate data for attenuation correction. A first prototype has been built using a commercially available plane silicon diode detector. A cone-beam reconstruction provides the images using the Feldkamp algorithm. First measurements with this system have been performed on a mouse. It could be shown that the CT setup fulfils all demands for a high quality image of the skeleton of the mouse. It is also suited for soft tissue measurements. To improve contrast and resolution and to acquire the X-ray energy further development of the system, especially the use of semiconductor detectors and iterative reconstruction algorithms are planned.}, language = {en} } @article{StreunBrandenburgLarueetal.2002, author = {Streun, M. and Brandenburg, G. and Larue, H. and Zimmermann, E. and Ziemons, Karl and Halling, H.}, title = {A PET system based on data processing of free-running sampled pulses}, series = {2001 IEEE Nuclear Science Symposium Conference Record, Vol. 2}, journal = {2001 IEEE Nuclear Science Symposium Conference Record, Vol. 2}, issn = {1082-3654}, pages = {693 -- 694}, year = {2002}, abstract = {Within the developments for the Crystal Clear small animal PET project (CLEARPET) a dual head PET system has been established. The basic principle is the early digitization of the detector pulses by free running ADCs. The determination of the γ-energy and also the coincidence detection is performed by data processing of the sampled pulses on the host computer. Therefore a time mark is attached to each pulse identifying the current cycle of the 40 MHz sampling clock. In order to refine the time resolution the pulse starting time is interpolated from the samples of the pulse rise. The detector heads consist of multichannel PMTs with a single LSO scintillator crystal coupled to each channel. For each PMT only one ADC is required. The position of an event is obtained separately from trigger signals generated for each single channel. An FPGA is utilized for pulse buffering, generation of the time mark and for the data transfer to the host via a fast I/O-interface.}, language = {en} } @article{HeinrichsPietrzykZiemons2003, author = {Heinrichs, U. and Pietrzyk, U. and Ziemons, Karl}, title = {Design optimization of the PMT-ClearPET prototypes based on simulation studies with GEANT3}, series = {2002 IEEE Nuclear Science Symposium Conference Record, Vol. 3}, journal = {2002 IEEE Nuclear Science Symposium Conference Record, Vol. 3}, issn = {1082-3654}, pages = {682 -- 686}, year = {2003}, abstract = {Within the Crystal Clear Collaboration four centres are developing 2nd generation high performance small animal PET scanners for different kinds of animals and medical applications. The first prototypes are PMT-based systems including depth of interaction (DOI) detection by using a phoswich layer of LSO and LuYAP. The aim of these simulation studies is to optimize sensitivity and spatial resolution of given designs, which vary in FOVs caused by different detector configurations (ring/octagon) and sizes. For this purpose the simulation tool GEANT3 (CERN) was used. The simulations have shown that all PMT designs with one-to-one coupling of crystals have a very nonlinear axial sensitivity profile. By shifting every other PMT 1/4 of a PMT length in axial direction the sampling of the FOVs became more homogeneous. At an energy threshold of 350keV the regression coefficient increases from 0.818 for the non-shifted to 0.993 for the shifted design. Simulations of a point source centred in the FOV (threshold: 350keV) resulted in sensitivities of 4.2\% for a 4×20PMT (LSO/LuYAP a 10mm) and 3.8\% for a 4×16PMT (LSO/LuYAP a 8mm) ring design. The 3D-MLEM reconstruction of a point source shows the enormous improvement of resolution using a crystal double layer with DOI (3.1mm at 40mm from CFOV) instead of a 20mm single layer (11.9mm).}, language = {en} } @article{HeinrichsPietrzykZiemons2003, author = {Heinrichs, U. and Pietrzyk, U. and Ziemons, Karl}, title = {Design optimization of the PMT-ClearPET prototypes based on simulation studies with GEANT3}, series = {IEEE Transactions on Nuclear Science}, volume = {50}, journal = {IEEE Transactions on Nuclear Science}, number = {5}, isbn = {0018-9499}, pages = {1428 -- 1432}, year = {2003}, abstract = {Within the Crystal Clear Collaboration (CCC), four centers are developing second generation high performance small animal positron emission tomography (PET) scanners for different kinds of animals and medical applications. The first prototypes are photomultiplier tube (PMT)-based systems including depth of interaction (DOI) detection by using a phoswich layer of lutetium oxyorthosilicate (LSO) and lutetium yttrium aluminum perovskite (LuYAP). The aim of these simulation studies is to optimize sensitivity and spatial resolution of given designs, which vary in fields of view (FOVs) caused by different detector configurations (ring/octagon) and sizes. For this purpose the simulation tool GEANT3 (CERN, Geneva, Switzerland) was used.}, language = {en} } @article{StreunBrandenburgLarueetal.2003, author = {Streun, M. and Brandenburg, G. and Larue, H. and Saleh, H. and Zimmermann, E. and Ziemons, Karl and Halling, H.}, title = {Pulse shape discrimination of LSO and LuYAP scintillators for depth of interaction detection in PET}, series = {2002 IEEE Nuclear Science Symposium Conference Record, Vol. 3}, journal = {2002 IEEE Nuclear Science Symposium Conference Record, Vol. 3}, issn = {1082-3654}, pages = {1636 -- 1639}, year = {2003}, abstract = {A feasible way to gain the depth of interaction information in a PET scanner is the use of phoswich detectors. In general the layer of interaction is identified front the pulse shape of the corresponding scintillator material. In this work pulses from LSO and LuYAP crystals were investigated in order to find a practical method of distinguishing. It turned out that such a pulse processing could he kept simple due to an additional slow component in the light decay of the LuYAP pulse. At the same time the short decay time guarantees that the major amount of the light output is still collected within a short pulse recording time.}, language = {en} } @article{StreunBrandenburgLarueetal.2003, author = {Streun, M. and Brandenburg, G. and Larue, H. and Saleh, H. and Zimmermann, E. and Ziemons, Karl and Halling, H.}, title = {Pulse shape discrimination of LSO and LuYAP scintillators for depth of interaction detection in PET}, series = {IEEE Transactions on Nuclear Science}, volume = {50}, journal = {IEEE Transactions on Nuclear Science}, number = {3}, isbn = {0018-9499}, pages = {344 -- 347}, year = {2003}, abstract = {A feasible way to gain the depth of interaction information in a positron emission tomography scanner is the use of phoswich detectors. In general, the layer of interaction is identified from the pulse shape of the corresponding scintillator material. In this work, pulses from LSO and LuYAP crystals were investigated in order to find a practical method of distinguishing. It turned out that such a pulse processing could be kept simple because of an additional slow component in the light decay of the LuYAP pulse. At the same time, the short decay time guarantees that the major amount of the light output is still collected within a short pulse recording time.}, language = {en} } @article{KhodaverdiChaziioannouWeberetal.2004, author = {Khodaverdi, M. and Chaziioannou, A. F. and Weber, S. and Ziemons, Karl and Halling, H. and Pietrzyk, U.}, title = {Investigation of different microCT scanner configurations by GEANT4 simulations}, series = {2003 IEEE Nuclear Science Symposium Conference Record, Vol. 4}, journal = {2003 IEEE Nuclear Science Symposium Conference Record, Vol. 4}, issn = {1082-3654}, pages = {2989 -- 2993}, year = {2004}, abstract = {This study has been performed to design the combination of the new ClearPET TM (ClearPET is a trademark of the Crystal Clear Collaboration), a small animal Positron Emission Tomography (PET) system, with a microComputed Tomography (microCT) scanner. The properties of different microCT systems have been determined by simulations based on GEANT4. We demonstrate the influence of the detector material and the X-ray spectrum on the obtained contrast. Four different detector materials (selenium, cadmium zinc telluride, cesium iodide and gadolinium oxysulfide) and two X-ray spectra (a molybdenum and a tungsten source) have been considered. The spectra have also been modified by aluminum filters of varying thickness. The contrast between different tissue types (water, air, brain, bone and fat) has been simulated by using a suitable phantom. The results indicate the possibility to improve the image contrast in microCT by an optimized combination of the X-ray source and detector material.}, language = {en} } @article{ZiemonsAuffrayBarbieretal.2004, author = {Ziemons, Karl and Auffray, E. and Barbier, R. and Brandenburg, G.}, title = {The ClearPET TM LSO/LuYAP phoswich scanner: a high performance small animal PET system}, series = {2003 IEEE Nuclear Science Symposium Conference Record, Vol. 3}, journal = {2003 IEEE Nuclear Science Symposium Conference Record, Vol. 3}, issn = {1082-3654}, pages = {1728 -- 1732}, year = {2004}, abstract = {A 2nd generation high performance small animal PET scanner, called ClearPET™, has been designed and a first prototype is built by working groups of the Crystal Clear Collaboration (CCC). In order to achieve high sensitivity and maintain good uniform spatial resolution over the field of view in high resolution PET systems, it is necessary to extract the depth of interaction (DOI) information and correct for spatial degradation. The design of the first ClearPET™ Demonstrator based on the use of the multi-anode photomultiplier tube (Hamamatsu R7600-M64) and a LSO/LuYAP phoswich matrix. The two crystal layers of 8*8 crystals (2*2*10 mm3) are stacked on each other and mounted without light guide as one to one on the PMT. A unit of four PMTs arranged in-line represents one of 20 sectors of the ring design. The opening diameter of the crystal ring is 137 mm, the axial detector length is 110 mm. The PMT pulses are digitized by free-running ADCs and digital data processing determines the gamma energy, the phoswich layer and even the pulse arrival time. Single gamma interactions are recorded and coincidences are found by software. The gantry allows rotation of the detector modules around the field of view. The measurements have been done using the first LSO/LuYAP detector cassettes.}, language = {en} } @article{StreunBrandenburgBroekeletal.2004, author = {Streun, M. and Brandenburg, G. and Br{\"o}kel, M. and Fuss, L. and Larue, H. and Parl, C. and Zimmermann, E. and Ziemons, Karl and Halling, H.}, title = {The ClearPET data acquisition}, series = {2003 IEEE Nuclear Science Symposium Conference Record, Vol. 5}, journal = {2003 IEEE Nuclear Science Symposium Conference Record, Vol. 5}, issn = {1082-3654}, pages = {3097 -- 3100}, year = {2004}, abstract = {Within the Crystal Clear Collaboration a modular system for a small animal PET scanner (ClearPET™) has been developed. The modularity allows the assembly of scanners of different sizes and characteristics in order to fit the specific needs of the individual member institutions. Now a first demonstrator is being completed in Julich. The system performs depth of interaction detection by using a phoswich arrangement combining LSO and LuYAP scintillators which are coupled to multi-channel photomultipliers (PMTs). A free-running ADC digitizes the signal from the PMT and the complete scintillation pulses are sampled by an FPGA and sent with 20 MB/S to a PC for preprocessing. The pulse provides information about the gamma energy and the scintillator material which identifies the interaction layer. Furthermore, the exact pulse starting time is obtained from the sampled data. This is important as no hardware coincidence detection is implemented. All single events are recorded and coincidences are identified by software. An advantage of that is that the coincidence window and the dimensions of the field of view can be adjusted easily. The ClearPET™ demonstrator is equipped with 10240 crystals on 80 PMTs. This paper presents an overview of the data acquisition system.}, language = {en} }