@article{WernerGroebelKrumbeetal.2012,
  author    = {Werner, Frederik and Groebel, Simone and Krumbe, Christoph and Wagner, Torsten and Selmer, Thorsten and Yoshinobu, Tatsuo and Baumann, Marcus and Sch{\"o}ning, Michael Josef},
  title     = {Nutrient concentration-sensitive microorganism-based biosensor},
  series = {Physica Status Solidi (a)},
  volume    = {209},
  journal   = {Physica Status Solidi (a)},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201100801},
  pages     = {900 -- 904},
  year      = {2012},
  language  = {en}
}
@article{WernerKrumbeSchumacheretal.2011,
  author    = {Werner, Frederik and Krumbe, Christoph and Schumacher, Katharina and Groebel, Simone and Spelthahn, Heiko and Stellberg, Michael and Wagner, Torsten and Yoshinobu, Tatsuo and Selmer, Thorsten and Keusgen, Michael and Baumann, Marcus and Sch{\"o}ning, Michael Josef},
  title     = {Determination of the extracellular acidification of Escherichia coli by a light-addressable potentiometric sensor},
  series = {Physica status solidi (a) : applications and material science. 208 (2011), H. 6},
  journal   = {Physica status solidi (a) : applications and material science. 208 (2011), H. 6},
  publisher = {Wiley},
  address   = {Weinheim},
  isbn      = {1862-6319},
  pages     = {1340 -- 1344},
  year      = {2011},
  language  = {en}
}
@article{WernerMiyamotoWagneretal.2017,
  author    = {Werner, Frederik and Miyamoto, Ko-ichiro and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo},
  title     = {Lateral resolution enhancement of pulse-driven light-addressable potentiometric sensor},
  series = {Sensor and Actuators B: Chemical},
  volume    = {248},
  journal   = {Sensor and Actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2017.02.057},
  pages     = {961 -- 965},
  year      = {2017},
  abstract  = {To study chemical and biological processes, spatially resolved determination of the concentrations of one or more analyte species is of distinct interest. With a light-addressable potentiometric sensor (LAPS), chemical images can be created, which visualize the concentration distribution above the sensor plate. One important challenge is to achieve a good lateral resolution in order to detect events that take place in a small and limited region. LAPS utilizes a focused light spot to address the measurement region. By moving this light spot along the semiconductor sensor plate, the concentration distribution can be observed. In this study, we show that utilizing a pulse as light excitation instead of a traditionally used continuously modulated light excitation, the lateral resolution can be improved by a factor of 6 or more.},
  language  = {en}
}
@article{WernerSchusserSpalthahnetal.2011,
  author    = {Werner, Frederik and Schusser, Sebastian and Spalthahn, Heiko and Wagner, Torsten and Yoshinobu, Tatsuo and Sch{\"o}ning, Michael Josef},
  title     = {Field-programmable gate array based controller for multi spot light-addressable potentiometric sensors with integrated signal correction mode},
  series = {Electrochimica Acta},
  volume    = {56},
  journal   = {Electrochimica Acta},
  number    = {26},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0013-4686},
  doi       = {10.1016/j.electacta.2011.03.012},
  pages     = {9656 -- 9660},
  year      = {2011},
  abstract  = {A light-addressable potentiometric sensor (LAPS) can measure the concentration of one or several analytes at the sensor surface simultaneously in a spatially resolved manner. A modulated light pointer stimulates the semiconductor structure at the area of interest and a responding photocurrent can be read out. By simultaneous stimulation of several areas with light pointers of different modulation frequencies, the read out can be performed at the same time. With the new proposed controller electronic based on a field-programmable gate array (FPGA), it is possible to control the modulation frequencies, phase shifts, and light brightness of multiple light pointers independently and simultaneously. Thus, it is possible to investigate the frequency response of the sensor, and to examine the analyte concentration by the determination of the surface potential with the help of current/voltage curves and phase/voltage curves. Additionally, the ability to individually change the light intensities of each light pointer is used to perform signal correction.},
  language  = {en}
}
@article{WernerTakenagaTakietal.2013,
  author    = {Werner, Frederik and Takenaga, Shoko and Taki, Hidenori and Sawada, Kazuaki and Sch{\"o}ning, Michael Josef},
  title     = {Comparison of label-free ACh-imaging sensors based on CCD and LAPS},
  series = {Sensors and Actuators B: Chemical (2012)},
  volume    = {177},
  journal   = {Sensors and Actuators B: Chemical (2012)},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {0925-4005},
  pages     = {745 -- 752},
  year      = {2013},
  abstract  = {Semiconductor-based chemical imaging sensors, like the light-addressable potentiometric sensor (LAPS) or the pH-imaging sensor based on a charge-coupled device (CCD), are becoming a powerful tool for label-free imaging of biological phenomena. We have proposed a polyion-based enzymatic membrane to develop an acetylcholine (ACh) imaging sensor for neural cell-activity observations. In this study, a CCD-type ACh-imaging sensor and a LAPS-type ACh-imaging sensor were fabricated and the prospect of both sensors was clarified by making a comparison of their basic characteristics.},
  language  = {en}
}
@article{WernerWagnerMiyamotoetal.2012,
  author    = {Werner, Frederik and Wagner, Torsten and Miyamoto, Ko-ichiro and Yoshinobu, Tatsuo and Sch{\"o}ning, Michael Josef},
  title     = {High speed and high resolution chemical imaging based on a new type of OLED-LAPS set-up},
  series = {Sensors and Actuators B: Chemical},
  volume    = {175},
  journal   = {Sensors and Actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2011.12.102},
  pages     = {118 -- 122},
  year      = {2012},
  abstract  = {Light-addressable potentiometric sensors (LAPS) are field-effect-based sensors. A modulated light source is used to define the particular measurement spot to perform spatially resolved measurements of chemical species and to generate chemical images. In this work, an organic-LED (OLED) display has been chosen as a light source. This allows high measurement resolution and miniaturisation of the system. A new developed driving method for the OLED display optimised for LAPS-based measurements is demonstrated. The new method enables to define modulation frequencies between 1 kHz and 16 kHz and hence, reduces the measurement time of a chemical image by a factor of 40 compared to the traditional addressing of an OLED display.},
  language  = {en}
}
@article{WernerWagnerMiyamotoetal.2011,
  author    = {Werner, Frederik and Wagner, Torsten and Miyamoto, Ko-ichiro and Yoshinobu, Tatsuo and Sch{\"o}ning, Michael Josef},
  title     = {High speed and high resolution chemical imaging based on a new type of OLED-LAPS set-up},
  series = {Procedia Engineering. 25 (2011)},
  journal   = {Procedia Engineering. 25 (2011)},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {1877-7058},
  pages     = {346 -- 349},
  year      = {2011},
  language  = {en}
}
@article{WernerWagnerYoshinobuetal.2013,
  author    = {Werner, Frederik and Wagner, Torsten and Yoshinobu, Tatsuo and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Frequency behaviour of light-addressable potentiometric sensors},
  series = {Physica Status Solidi (A)},
  volume    = {210},
  journal   = {Physica Status Solidi (A)},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-396X ; 0031-8965},
  doi       = {10.1002/pssa.201200929},
  pages     = {884 -- 891},
  year      = {2013},
  abstract  = {Light-addressable potentiometric sensors (LAPS) are semiconductor-based potentiometric sensors, with the advantage to detect the concentration of a chemical species in a liquid solution above the sensor surface in a spatially resolved manner. The addressing is achieved by a modulated and focused light source illuminating the semiconductor and generating a concentration-depending photocurrent. This work introduces a LAPS set-up that is able to monitor the electrical impedance in addition to the photocurrent. The impedance spectra of a LAPS structure, with and without illumination, as well as the frequency behaviour of the LAPS measurement are investigated. The measurements are supported by electrical equivalent circuits to explain the impedance and the LAPS-frequency behaviour. The work investigates the influence of different parameters on the frequency behaviour of the LAPS. Furthermore, the phase shift of the photocurrent, the influence of the surface potential as well as the changes of the sensor impedance will be discussed.},
  language  = {en}
}
@article{WertIkenSchoeningetal.2021,
  author    = {Wert, Stefan and Iken, Heiko and Sch{\"o}ning, Michael Josef and Matysik, Frank-Michael},
  title     = {Development of a temperature-pulse enhanced electrochemical glucose biosensor and characterization of its stability via scanning electrochemical microscopy},
  series = {Electroanalysis},
  journal   = {Electroanalysis},
  number    = {Early View},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-4109},
  doi       = {10.1002/elan.202100089},
  year      = {2021},
  abstract  = {Glucose oxidase (GOx) is an enzyme frequently used in glucose biosensors. As increased temperatures can enhance the performance of electrochemical sensors, we investigated the impact of temperature pulses on GOx that was drop-coated on flattened Pt microwires. The wires were heated by an alternating current. The sensitivity towards glucose and the temperature stability of GOx was investigated by amperometry. An up to 22-fold increase of sensitivity was observed. Spatially resolved enzyme activity changes were investigated via scanning electrochemical microscopy. The application of short (<100 ms) heat pulses was associated with less thermal inactivation of the immobilized GOx than long-term heating.},
  language  = {en}
}
@article{WhiteheadOehlschlaegerAlmajhdietal.2014,
  author    = {Whitehead, Mark and {\"O}hlschl{\"a}ger, Peter and Almajhdi, Fahad N. and Alloza, Leonor and Marz{\´a}bal, Pablo and Meyers, Ann E. and Hitzeroth, Inga I. and Rybicki, Edward P.},
  title     = {Human papillomavirus (HPV) type 16 E7 protein bodies cause tumour regression in mice},
  series = {BMC cancer},
  journal   = {BMC cancer},
  number    = {14:367},
  publisher = {BioMed Central},
  address   = {London},
  issn      = {1471-2407},
  doi       = {10.1186/1471-2407-14-367},
  pages     = {1 -- 15},
  year      = {2014},
  language  = {en}
}
@article{WiegandDietrichHerteletal.2013,
  author    = {Wiegand, Sandra and Dietrich, Sascha and Hertel, Robert and Bongaerts, Johannes and Evers, Stefan and Volland, Sonja and Daniel, Rolf and Liesegang, Heiko},
  title     = {RNA-Seq of Bacillus licheniformis: active regulatory RNA features expressed within a productive fermentation},
  series = {BMC genomics},
  volume    = {Vol. 14},
  journal   = {BMC genomics},
  publisher = {BioMed Central},
  address   = {London},
  issn      = {1471-2164},
  pages     = {667},
  year      = {2013},
  language  = {en}
}
@article{WiegandVoigtAlbrechtetal.2013,
  author    = {Wiegand, Sandra and Voigt, Birgit and Albrecht, Dirk and Bongaerts, Johannes and Evers, Stefan and Hecker, Michael and Daniel, Rolf and Liesegang, Heiko},
  title     = {Fermentation stage-dependent adaptations of Bacillus licheniformis during enzyme production},
  series = {Microbial Cell Factories},
  volume    = {12},
  journal   = {Microbial Cell Factories},
  publisher = {Biomed Central},
  address   = {London},
  issn      = {1475-2859},
  doi       = {10.1186/1475-2859-12-120},
  pages     = {120},
  year      = {2013},
  language  = {en}
}
@article{WiegnerVolkerMainzetal.2023,
  author    = {Wiegner, Jonas and Volker, Hanno and Mainz, Fabian and Backes, Andreas and Loeken, Michael and H{\"u}ning, Felix},
  title     = {Energy analysis of a wireless sensor node powered by a Wiegand sensor},
  series = {Journal of Sensors and Sensor Systems (JSSS)},
  volume    = {12},
  journal   = {Journal of Sensors and Sensor Systems (JSSS)},
  number    = {1},
  publisher = {Copernicus Publ.},
  address   = {G{\"o}ttingen},
  issn      = {2194-878X},
  doi       = {10.5194/jsss-12-85-2023},
  pages     = {85 -- 92},
  year      = {2023},
  abstract  = {This article describes an Internet of things (IoT) sensing device with a wireless interface which is powered by the energy-harvesting method of the Wiegand effect. The Wiegand effect, in contrast to continuous sources like photovoltaic or thermal harvesters, provides small amounts of energy discontinuously in pulsed mode. To enable an energy-self-sufficient operation of the sensing device with this pulsed energy source, the output energy of the Wiegand generator is maximized. This energy is used to power up the system and to acquire and process data like position, temperature or other resistively measurable quantities as well as transmit these data via an ultra-low-power ultra-wideband (UWB) data transmitter. A proof-of-concept system was built to prove the feasibility of the approach. The energy consumption of the system during start-up was analysed, traced back in detail to the individual components, compared to the generated energy and processed to identify further optimization options. Based on the proof of concept, an application prototype was developed.},
  language  = {en}
}
@article{WiesenTippkoetterMuffleretal.2015,
  author    = {Wiesen, Sebastian and Tippk{\"o}tter, Nils and Muffler, Kai and Suck, Kirstin and Sohling, Ulrich and Ruf, Friedrich and Ulber, Roland},
  title     = {Adsorption of fatty acids to layered double hydroxides in aqueous systems},
  series = {Adsorption},
  volume    = {21},
  journal   = {Adsorption},
  number    = {6-7},
  publisher = {Springer},
  address   = {Berlin},
  pages     = {459 -- 466},
  year      = {2015},
  abstract  = {Due to their anion exchange characteristics, layered double hydroxides (LDHs) are suitable for the detoxification of aqueous, fatty acid containing fermentation substrates. The aim of this study is to examine the adsorption mechanism, using crude glycerol from plant oil esterification as a model system. Changes in the intercalation structure in relation to the amount of fatty acids adsorbed are monitored by X-ray diffraction and infra-red spectroscopy. Additionally, calcination of LDH is investigated in order to increase the binding capacity for fatty acids. Our data propose that, at ambient temperature, fatty acids can be bound to the hydrotalcite by adsorption or in addition by intercalation, depending on fatty acid concentration. The adsorption of fatty acids from crude glycerol shows a BET-like behavior. Above a fatty acid concentration of 3.5 g L-1, intercalation of fatty acids can be shown by the appearance of an increased interlayer spacing. This observation suggests a two phase adsorption process. Calcination of LDHs allows increasing the binding capacity for fatty acids by more than six times, mainly by reduction of structural CO32-.},
  language  = {en}
}
@article{WildSchrezenmeierCzupallaetal.2020,
  author    = {Wild, Dominik and Schrezenmeier, Johannes and Czupalla, Markus and F{\"o}rstner, Roger},
  title     = {Thermal Characterization of additive manufactured Integral Structures for Phase Change Applications},
  series = {2020 International Conference on Environmental Systems},
  journal   = {2020 International Conference on Environmental Systems},
  publisher = {Texas Tech University},
  year      = {2020},
  abstract  = {"Infused Thermal Solutions" (ITS) introduces a method for passive thermal control to stabilize structural components thermally without active heating and cooling systems, by using phase change material (PCM) in combination with lattice - both embedded into an additive manufactured integral structure. The technology is currently under development. This paper presents the results of the thermal property measurements performed on additive manufactured ITS breadboards. Within the breadboard campaigns key characteristics of the additive manufactured specimens were derived: Mechanical parameters: specimen impermeability, minimum wall thickness, lattice structure, subsequent heat treatment. Thermal properties: thermo-optical surface properties of the additive manufactured raw material, thermal conductivity and specific heat capacity measurements. As a conclusion the paper introduces an overview of potential ITS hardware applications, expected to increase the thermal performance.},
  language  = {en}
}
@article{Wilke2017,
  author    = {Wilke, Thomas},
  title     = {Newly found plans for the chapel of the Holy Shroud},
  series = {Studi Piemontesi},
  volume    = {XLVI},
  journal   = {Studi Piemontesi},
  number    = {1},
  issn      = {0392-7261},
  pages     = {75 -- 85},
  year      = {2017},
  language  = {en}
}
@article{WilmingBegemannKuhneetal.2013,
  author    = {Wilming, Anja and Begemann, Jens and Kuhne, Stefan and Regestein, Lars and Bongaerts, Johannes and Evers, Stefan and Maurer, Karl-Heinz and B{\"u}chs, Jochen},
  title     = {Metabolic studies of γ-polyglutamic acid production in Bacillus licheniformis by small-scale continuous cultivations},
  series = {Biochemical engineering journal},
  volume    = {Vol. 73},
  journal   = {Biochemical engineering journal},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-295X (E-Journal); 1369-703X (Print)},
  pages     = {29 -- 37},
  year      = {2013},
  language  = {en}
}
@article{WilsonDickieSchreiteretal.2018,
  author    = {Wilson, C. E. and Dickie, A. P. and Schreiter, K. and Wehr, R. and Wilson, E. M. and Bial, J. and Scheer, Nico and Wilson, I. D. and Riley, R. J.},
  title     = {The pharmacokinetics and metabolism of diclofenac in chimeric humanized and murinized FRG mice},
  series = {Archives of Toxicology},
  volume    = {92},
  journal   = {Archives of Toxicology},
  number    = {6},
  publisher = {Springer},
  issn      = {1432-0738},
  doi       = {10.1007/s00204-018-2212-1},
  pages     = {1953 -- 1967},
  year      = {2018},
  abstract  = {The pharmacokinetics of diclofenac were investigated following single oral doses of 10 mg/kg to chimeric liver humanized and murinized FRG and C57BL/6 mice. In addition, the metabolism and excretion were investigated in chimeric liver humanized and murinized FRG mice. Diclofenac reached maximum blood concentrations of 2.43 ± 0.9 µg/mL (n = 3) at 0.25 h post-dose with an AUCinf of 3.67 µg h/mL and an effective half-life of 0.86 h (n = 2). In the murinized animals, maximum blood concentrations were determined as 3.86 ± 2.31 µg/mL at 0.25 h post-dose with an AUCinf of 4.94 ± 2.93 µg h/mL and a half-life of 0.52 ± 0.03 h (n = 3). In C57BL/6J mice, mean peak blood concentrations of 2.31 ± 0.53 µg/mL were seen 0.25 h post-dose with a mean AUCinf of 2.10 ± 0.49 µg h/mL and a half-life of 0.51 ± 0.49 h (n = 3). Analysis of blood indicated only trace quantities of drug-related material in chimeric humanized and murinized FRG mice. Metabolic profiling of urine, bile and faecal extracts revealed a complex pattern of metabolites for both humanized and murinized animals with, in addition to unchanged parent drug, a variety of hydroxylated and conjugated metabolites detected. The profiles in humanized mice were different to those of both murinized and wild-type animals, e.g., a higher proportion of the dose was detected in the form of acyl glucuronide metabolites and much reduced amounts as taurine conjugates. Comparison of the metabolic profiles obtained from the present study with previously published data from C57BL/6J mice and humans revealed a greater, though not complete, match between chimeric humanized mice and humans, such that the liver humanized FRG model may represent a model for assessing the biotransformation of such compounds in humans.},
  language  = {en}
}
@article{WilsonWilsonScheeretal.2017,
  author    = {Wilson, Ian D. and Wilson, Claire E. and Scheer, Nico and Dickie, A.P. and Schreiter, K. and Wilson, E. M. and Riley, R. J. and Wehr, R. and Bial, J.},
  title     = {The Pharmacokinetics and Metabolism of Lumiracoxib in Chimeric Humanized and Murinized FRG Mice},
  series = {Biochemical pharmacology},
  volume    = {Volume 135},
  journal   = {Biochemical pharmacology},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-2968},
  doi       = {10.1016/j.bcp.2017.03.015},
  pages     = {139 -- 150},
  year      = {2017},
  language  = {en}
}
@article{WilsonBlome2009,
  author    = {Wilson, T. L. and Blome, Hans-Joachim},
  title     = {The Pioneer anomaly and a rotating G{\"o}del universe},
  series = {Advances in Space Research},
  volume    = {44},
  journal   = {Advances in Space Research},
  number    = {11},
  isbn      = {0273-1177},
  pages     = {1345 -- 1353},
  year      = {2009},
  language  = {en}
}
@article{WilsonBlomeLaFave1996,
  author    = {Wilson, Thomas L and Blome, Hans-Joachim and LaFave, Norman},
  title     = {Astrophysical Cosmology Using a Lunar Ligo},
  series = {Engineering, construction, and operations in space V : proceedings of the Fifth International Conference on Space '96, Albuquerque, New Mexico, June 1-6, 1996 / sponsored by Aerospace Division of the American Society of Civil Engineers ... [et al.]; edite},
  journal   = {Engineering, construction, and operations in space V : proceedings of the Fifth International Conference on Space '96, Albuquerque, New Mexico, June 1-6, 1996 / sponsored by Aerospace Division of the American Society of Civil Engineers ... [et al.]; edite},
  publisher = {The Society},
  address   = {New York},
  isbn      = {0-7844-0177-2},
  pages     = {861 -- 863},
  year      = {1996},
  language  = {en}
}
@article{WincklerKruegerSchnitzleretal.2014,
  author    = {Winckler, Silvia and Krueger, Rolf and Schnitzler, Thomas and Zang, Werner and Fischer, Rainer and Biselli, Manfred},
  title     = {A sensitive monitoring system for mammalian cell cultivation processes: a PAT approach},
  series = {Bioprocess and biosystems engineering},
  volume    = {37},
  journal   = {Bioprocess and biosystems engineering},
  number    = {5},
  publisher = {Springer},
  address   = {Berlin, Heidelberg},
  issn      = {1615-7591 (Print) 1615-7605 (Online)},
  doi       = {10.1007/s00449-013-1062-8},
  pages     = {901 -- 912},
  year      = {2014},
  abstract  = {Biopharmaceuticals such as antibodies are produced in cultivated mammalian cells, which must be monitored to comply with good manufacturing practice. We, therefore, developed a fully automated system comprising a specific exhaust gas analyzer, inline analytics and a corresponding algorithm to precisely determine the oxygen uptake rate, carbon dioxide evolution rate, carbon dioxide transfer rate, transfer quotient and respiratory quotient without interrupting the ongoing cultivation, in order to assess its reproducibility. The system was verified using chemical simulation experiments and was able to measure the respiratory activity of hybridoma cells and DG44 cells (derived from Chinese hamster ovary cells) with satisfactory results at a minimum viable cell density of ~2.0 × 10⁵ cells ml⁻¹. The system was suitable for both batch and fed-batch cultivations in bubble-aerated and membrane-aerated reactors, with and without the control of pH and dissolved oxygen.},
  language  = {en}
}
@article{WissenBogdanskiScheeretal.2005,
  author    = {Wissen, M. and Bogdanski, N. and Scheer, H.-C. and Bitz, Andreas and Ahrens, G. and Gruetzner, G.},
  title     = {Implication of the light polarisation for UV curing of pre-patterned resists},
  series = {Microelectronic Engineering},
  volume    = {78-79},
  journal   = {Microelectronic Engineering},
  issn      = {0167-9317},
  doi       = {10.1016/j.mee.2004.12.099},
  pages     = {659 -- 664},
  year      = {2005},
  language  = {en}
}
@article{WissenbachSixBongaertsetal.1995,
  author    = {Wissenbach, U. and Six, S. and Bongaerts, Johannes and Ternes, D. and Steinwachs, S. and Unden, G.},
  title     = {A third periplasmic transport system for l-arginine in Escherichia coli: molecular characterization of the artPIQMJ genes, arginine binding and transport},
  series = {Molecular microbiology},
  volume    = {Vol. 17},
  journal   = {Molecular microbiology},
  number    = {Iss. 4},
  issn      = {1365-2958 (E-Journal); 0950-382x (Print)},
  pages     = {675 -- 686},
  year      = {1995},
  language  = {en}
}
@article{Wittmann1993,
  author    = {Wittmann, Klaus},
  title     = {The microgravity User Support Centre},
  series = {Space Technology - Industrial and Commercial Applications. 13 (1993), H. 2},
  journal   = {Space Technology - Industrial and Commercial Applications. 13 (1993), H. 2},
  isbn      = {0892-9270},
  pages     = {121 -- 124},
  year      = {1993},
  language  = {en}
}
@article{Wittmann2000,
  author    = {Wittmann, Klaus},
  title     = {Overview of Space Operations at DLR},
  year      = {2000},
  language  = {en}
}
@article{WittmannBewersdorffGoerleretal.1993,
  author    = {Wittmann, Klaus and Bewersdorff, A. and G{\"o}rler, G.P. and Otto, G.},
  title     = {Solidification of silver-germanium alloys in an amorphous matrix aboard the space station Mir},
  series = {Acta Astronautica. 29 (1993), H. 7},
  journal   = {Acta Astronautica. 29 (1993), H. 7},
  isbn      = {0094-5765},
  pages     = {547 -- 552},
  year      = {1993},
  language  = {en}
}
@article{WittmannBibringRosenbaueretal.2007,
  author    = {Wittmann, Klaus and Bibring, J.-P. and Rosenbauer, H. and Boehnhardt, H.},
  title     = {The Rosetta Lander ("Philae") Investigations / Bibring, J.-P. ; Rosenbauer, H. ; Boehnhardt, H. ; [...] Wittmann, K.},
  series = {Space Science Reviews. 128 (2007), H. 1-4},
  journal   = {Space Science Reviews. 128 (2007), H. 1-4},
  isbn      = {0038-6308},
  pages     = {205 -- 220},
  year      = {2007},
  language  = {en}
}
@article{WittmannFeuerbacherUlamecetal.1999,
  author    = {Wittmann, Klaus and Feuerbacher, B. and Ulamec, S. and Rosenbauer, H. (u.a.)},
  title     = {Rosetta Lander - In Situ Characterisation of a Comet Nucleus},
  series = {Acta Astronautica. 45 (1999), H. 4-9},
  journal   = {Acta Astronautica. 45 (1999), H. 4-9},
  isbn      = {0094-5765},
  pages     = {389 -- 395},
  year      = {1999},
  language  = {en}
}
@article{WittmannFortezza1992,
  author    = {Wittmann, Klaus and Fortezza, R.},
  title     = {Telescience opportunities in the precursor flights},
  series = {Space Technology - Industrial and Commercial Applications. 13 (1992), H. 2},
  journal   = {Space Technology - Industrial and Commercial Applications. 13 (1992), H. 2},
  isbn      = {0892-9270},
  pages     = {221 -- 226},
  year      = {1992},
  language  = {en}
}
@article{WittmannGillessenOttoetal.1996,
  author    = {Wittmann, Klaus and Gillessen, F. and Otto, G. and R{\"o}stel, R.},
  title     = {Undercooling and solidification of metallic melts suspended in a non-nucleating matrix: Experiment NUCAL of the German Spacelab Mission D-2},
  series = {Acta Astronautica. 38 (1996), H. 1},
  journal   = {Acta Astronautica. 38 (1996), H. 1},
  isbn      = {0094-5765},
  pages     = {63 -- 68},
  year      = {1996},
  language  = {en}
}
@article{WittmannKehrWillnecker2000,
  author    = {Wittmann, Klaus and Kehr, J. and Willnecker, R.},
  title     = {Decentralized Payload Operations Concept for Columbus},
  year      = {2000},
  language  = {en}
}
@article{WittmannKellWinkleretal.1998,
  author    = {Wittmann, Klaus and Kell, G. and Winkler, F. and G{\"u}nther, M. (u.a.)},
  title     = {High resolution temperature measurement technique for materials sciences experiments in space},
  series = {Acta Astronautica. 43 (1998), H. 7-8},
  journal   = {Acta Astronautica. 43 (1998), H. 7-8},
  isbn      = {0094-5765},
  pages     = {385 -- 395},
  year      = {1998},
  language  = {en}
}
@article{WittmannPadeken1993,
  author    = {Wittmann, Klaus and Padeken, D.},
  title     = {The User Center for Microgravity MUSC - Support for space experiments},
  series = {DLR-Nachrichten. 70 (1993)},
  journal   = {DLR-Nachrichten. 70 (1993)},
  isbn      = {0937-0420},
  pages     = {19 -- 24},
  year      = {1993},
  language  = {en}
}
@article{WittmannSchmidtFeuerbacher1988,
  author    = {Wittmann, Klaus and Schmidt, H. P. and Feuerbacher, B.},
  title     = {Microgravity research and user support in the Space Station era: The Microgravity User Support Centre},
  series = {Acta Astronautica. 17 (1988), H. 11-12},
  journal   = {Acta Astronautica. 17 (1988), H. 11-12},
  isbn      = {0094-5765},
  pages     = {1161 -- 1168},
  year      = {1988},
  language  = {en}
}
@article{WittmannSchmidtPadekenetal.1988,
  author    = {Wittmann, Klaus and Schmidt, H. P. and Padeken, D. and Hildmann, B.},
  title     = {The Microgravity User Support Centre (MUSC)},
  series = {ESA SP. 277 (1988)},
  journal   = {ESA SP. 277 (1988)},
  isbn      = {0379-6566},
  pages     = {525},
  year      = {1988},
  language  = {en}
}
@article{WittmannUlamecRichter1999,
  author    = {Wittmann, Klaus and Ulamec, S and Richter, L},
  title     = {Lander Systems for Planetary Missions},
  series = {Laboratory astrophysics and space research / ed. by P. Ehrenfreund},
  journal   = {Laboratory astrophysics and space research / ed. by P. Ehrenfreund},
  publisher = {Kluwer},
  address   = {Dordrecht [u.a.]},
  isbn      = {0-7923-5338-2},
  pages     = {597 -- 621},
  year      = {1999},
  language  = {en}
}
@article{WittmannUlamecFeuerbacheretal.1995,
  author    = {Wittmann, Klaus and Ulamec, S. and Feuerbacher, B. and Rosenbauer, H.},
  title     = {Technical Challenge, Scientific Thrill: A Long Term Lander on an Active Comet},
  series = {Lunar and Planetary Science. 26 (1995)},
  journal   = {Lunar and Planetary Science. 26 (1995)},
  isbn      = {0270-9511},
  pages     = {1431 -- 1432},
  year      = {1995},
  language  = {en}
}
@article{WittmannUlamecFeuerbacheretal.1997,
  author    = {Wittmann, Klaus and Ulamec, S. and Feuerbacher, B. and Rosenbauer, H. (u.a.)},
  title     = {Rosetta Lander - In Situ Investigation of a Cometary Nucleus},
  series = {Lunar and Planetary Science. 28 (1997)},
  journal   = {Lunar and Planetary Science. 28 (1997)},
  isbn      = {0270-9511},
  pages     = {1461 -- 1462},
  year      = {1997},
  language  = {en}
}
@article{Wolf2000,
  author    = {Wolf, Martin},
  title     = {Groupware related task design},
  series = {ACM SIGGROUP Bulletin. 21 (2000), H. 2},
  journal   = {ACM SIGGROUP Bulletin. 21 (2000), H. 2},
  publisher = {-},
  pages     = {5 -- 8},
  year      = {2000},
  language  = {en}
}
@article{Wolf2000,
  author    = {Wolf, Martin},
  title     = {Groupware related task design},
  series = {ACM SIGGROUP Bulletin},
  volume    = {21},
  journal   = {ACM SIGGROUP Bulletin},
  number    = {2},
  issn      = {2372-7403},
  doi       = {10.1145/605660.605662},
  pages     = {5 -- 8},
  year      = {2000},
  abstract  = {his report summarizes the results of a workshop on Groupware related task design which took place at the International Conference on Supporting Group Work Group'99, Arizona, from 14 th to 17 th November 1999. The workshop was addressed to people from different viewpoints, backgrounds, and domains: - Researchers dealing with questions of task analysis and task modeling for Groupware application from an academic point of view. They may contribute modelbased design approaches or theoretically oriented work - Practitioners with experience in the design and everyday use of groupware systems. They might refer to the practical side of the topic: "real" tasks, "real" problems, "real" users, etc.},
  language  = {en}
}
@article{WolfFoltzKillichetal.2001,
  author    = {Wolf, Martin and Foltz, Christian and Killich, Stephan and Schmidt, Ludger},
  title     = {Task and Information Modeling for Cooperative Work / Foltz, Christian ; Killich, Stephan ; Wolf, Martin ; Schmidt, Ludger ; Luczak, Holger},
  series = {Systems, social and internationalization design aspects of human-computer interaction / ed. by Michael J. Smith, Gavriel Salvendy Vol. 2},
  journal   = {Systems, social and internationalization design aspects of human-computer interaction / ed. by Michael J. Smith, Gavriel Salvendy Vol. 2},
  publisher = {-},
  isbn      = {0-8058-3608-X},
  pages     = {172 -- 176},
  year      = {2001},
  language  = {en}
}
@article{WolfFoltzSchlicketal.2000,
  author    = {Wolf, Martin and Foltz, Christian and Schlick, Christopher and Luczak, Holger},
  title     = {Empirical Investigation of a workspace model for Chemical engineers / Wolf, Martin ; Foltz, Christian ; Schlick, Christopher ; Luczak, Holger},
  series = {Proceedings of the Human Factors and Ergonomics Society Annual Meeting July 2000. 44 (2000), H. 6},
  journal   = {Proceedings of the Human Factors and Ergonomics Society Annual Meeting July 2000. 44 (2000), H. 6},
  publisher = {-},
  pages     = {612 -- 615},
  year      = {2000},
  language  = {en}
}
@article{WolfFoltzSchlicketal.2002,
  author    = {Wolf, Martin and Foltz, Christian and Schlick, Christopher and Luczak, Holger},
  title     = {Development and evaluation of a groupware system to support chemical design processes / Wolf, Martin ; Foltz, Christian ; Schlick, Christopher ; Luczak, Holger},
  series = {International Journal of Human-Computer Interaction . 14 (2002), H. 2},
  journal   = {International Journal of Human-Computer Interaction . 14 (2002), H. 2},
  publisher = {-},
  isbn      = {1044-7318},
  pages     = {181 -- 198},
  year      = {2002},
  language  = {en}
}
@article{WolfFoltzSchlicketal.1999,
  author    = {Wolf, Martin and Foltz, Christian and Schlick, Christopher and Luczak, Holger},
  title     = {Groupware support for chemical process design / Wolf, M.; Foltz, C.; Schlick, C.; Luczak, H.},
  series = {Human-computer interaction : proceedings of HCI International '99 (the 8th International Conference on Human-Computer Interaction), Munich, Germany, August 22 - 26, 1999},
  journal   = {Human-computer interaction : proceedings of HCI International '99 (the 8th International Conference on Human-Computer Interaction), Munich, Germany, August 22 - 26, 1999},
  publisher = {Erlbaum},
  address   = {Mahwah, NJ},
  pages     = {343 -- 347},
  year      = {1999},
  language  = {en}
}
@article{WolfLuczak1999,
  author    = {Wolf, Martin and Luczak, Holger},
  title     = {Computer Supported Communication and Cooperation - Making Information Aware / Luczak, H. ; Wolf, M.},
  series = {Human-computer interaction : proceedings of HCI International '99 (the 8th International Conference on Human-Computer Interaction), Munich, Germany, August 22 - 26, 1999},
  journal   = {Human-computer interaction : proceedings of HCI International '99 (the 8th International Conference on Human-Computer Interaction), Munich, Germany, August 22 - 26, 1999},
  publisher = {Erlbaum},
  address   = {Mahwah, NJ},
  pages     = {298 -- 302},
  year      = {1999},
  language  = {en}
}
@article{WolfLuczakSpringeretal.1997,
  author    = {Wolf, Martin and Luczak, Holger and Springer, J. and Simon, S.},
  title     = {The role of metaphors in computer supported cooperative work},
  series = {Proceedings of WWDU '97 Tokyo, Fifth International Scientific Conference on Work with Display Units : November 3 - 5, 1997, Tokyo /},
  journal   = {Proceedings of WWDU '97 Tokyo, Fifth International Scientific Conference on Work with Display Units : November 3 - 5, 1997, Tokyo /},
  editor    = {Miyamoto, Hiroyuki},
  publisher = {-},
  address   = {Tokyo},
  pages     = {191 -- 192},
  year      = {1997},
  language  = {en}
}
@article{WolfSchlickSpringer1997,
  author    = {Wolf, Martin and Schlick, Christopher and Springer, J.},
  title     = {The use of implicit communication mechanisms in desktop-teleconferencing-systems},
  series = {Proceedings of WWDU '97 Tokyo, Fifth International Scientific Conference on Work with Display Units : November 3 - 5, 1997, Tokyo},
  journal   = {Proceedings of WWDU '97 Tokyo, Fifth International Scientific Conference on Work with Display Units : November 3 - 5, 1997, Tokyo},
  editor    = {Miyamoto, Hiroyuki},
  publisher = {-},
  address   = {Tokyo},
  pages     = {193 -- 194},
  year      = {1997},
  language  = {en}
}
@article{WolfSimonSchlick1998,
  author    = {Wolf, Martin and Simon, S. and Schlick, Christopher},
  title     = {Qualitative and Quantitative Analysis of Cooperation / Wolf, M. ; Simon, S. ; Schlick, C.},
  series = {Proceedings : May 26 - 29, 1998, Cannes (France) = Actes : 26 - 29 mai 1998 / INRIA, Institut National de Recherche en Informatique et en Automatique, Unit{\´e} de recherche ... F. Darses ..., eds},
  journal   = {Proceedings : May 26 - 29, 1998, Cannes (France) = Actes : 26 - 29 mai 1998 / INRIA, Institut National de Recherche en Informatique et en Automatique, Unit{\´e} de recherche ... F. Darses ..., eds},
  publisher = {-},
  address   = {Cannes},
  pages     = {1 -- 5},
  year      = {1998},
  language  = {en}
}
@article{WoliszSchuetzBlankeetal.2017,
  author    = {Wolisz, Henryk and Sch{\"u}tz, Thomas and Blanke, Tobias and Hagenkamp, Markus and Kohrn, Markus and Wesseling, Mark and M{\"u}ller, Dirk},
  title     = {Cost optimal sizing of smart buildings' energy system components considering changing end-consumer electricity markets},
  series = {Energy},
  volume    = {137},
  journal   = {Energy},
  publisher = {Elsevier},
  address   = {Amsterdam},
  doi       = {10.1016/j.energy.2017.06.025},
  pages     = {715 -- 728},
  year      = {2017},
  language  = {en}
}
@article{WollbrinkMasloZimmeretal.2020,
  author    = {Wollbrink, Moritz and Maslo, Semir and Zimmer, Daniel and Abbas, Karim and Arntz, Kristian and Bergs, Thomas},
  title     = {Clamping and substrate plate system for continuous additive build-up and post-processing of metal parts},
  series = {Procedia CIRP},
  volume    = {93},
  journal   = {Procedia CIRP},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2212-8271},
  doi       = {10.1016/j.procir.2020.04.015},
  pages     = {108 -- 113},
  year      = {2020},
  abstract  = {The manufacturing share of laser powder bed fusion (L-PBF) increases in industrial application, but still many process steps are manually operated. Additionally, it is not possible to achieve tight dimensional tolerances or low surfaces roughness. Hence, a process chain has to be set up to combine additive manufacturing (AM) with further machining technologies. To achieve a continuous workpiece flow as basis for further industrialization of L-PBF, the paper presents a novel substrate system and its application on L-PBF machines and post-processing. The substrate system consists of a zero-point clamping system and a matrix-like interface of contact pins to be substantially connected to the workpiece within the L-PBF process.},
  language  = {en}
}
@article{Wrede1996,
  author    = {Wrede, Oliver},
  title     = {Mnemotechnik in graphischen Benutzeroberfl{\"a}chen},
  series = {Form <Basel> / Form-Diskurs : Zeitschrift f{\"u}r Design und Theorie. 1 (1996), H. 2},
  journal   = {Form <Basel> / Form-Diskurs : Zeitschrift f{\"u}r Design und Theorie. 1 (1996), H. 2},
  year      = {1996},
  language  = {en}
}
@article{Wrede2016,
  author    = {Wrede, Oliver},
  title     = {Continuity in travel information},
  series = {Information Design Journal},
  volume    = {22},
  journal   = {Information Design Journal},
  number    = {2},
  publisher = {John Benjamins},
  address   = {Amsterdam},
  issn      = {0142-5471},
  doi       = {10.1075/idj.22.2.09wre},
  pages     = {172 -- 178},
  year      = {2016},
  abstract  = {This article discusses the contrast between the information transportation companies provide to travellers and that of their brand messaging. Companies' brand messaging often portrays the service they provide as pleasant, stress free and perfect. Customers and users of the service, on the other hand, often describe their experience of the service as a negative one. This article suggests that the brand value would be greater if transportation companies paid more attention to the users' experience when designing their information systems, particularly in worst case scenarios.},
  language  = {en}
}
@article{WuBronderPoghossianetal.2014,
  author    = {Wu, Chunsheng and Bronder, Thomas and Poghossian, Arshak and Werner, Frederik and B{\"a}cker, Matthias and Sch{\"o}ning, Michael Josef},
  title     = {Label-free electrical detection of DNA with a multi-spot LAPS: First step towards light-addressable DNA chips},
  series = {Physica status solidi A : Applications and materials science},
  volume    = {211},
  journal   = {Physica status solidi A : Applications and materials science},
  number    = {6},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)},
  doi       = {10.1002/pssa.201330442},
  pages     = {1423 -- 1428},
  year      = {2014},
  abstract  = {A multi-spot (4 × 4 spots) light-addressable potentiometric sensor (MLAPS) consisting of an Al-p-Si-SiO2 structure has been applied for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge for the first time. Single-stranded probe ssDNA molecules (20 bases) were covalently immobilized onto the silanized SiO2 gate surface. The unspecific adsorption of mismatch ssDNA on the MLAPS gate surface was blocked by bovine serum albumin molecules. To reduce the screening effect and to achieve a high sensor signal, the measurements were performed in a low ionic-strength solution. The photocurrent-voltage (I-V) curves were simultaneously recorded on all 16 spots after each surface functionalization step. Large shifts of I-V curves of 25 mV were registered after the DNA immobilization and hybridization event. In contrast, a small potential shift (∼5 mV) was observed in case of mismatch ssDNA, revealing good specificity of the sensor. The obtained results demonstrate the potential of the MLAPS as promising transducer platform for the multi-spot label-free electrical detection of DNA molecules by their intrinsic molecular charge.},
  language  = {en}
}
@article{WuBronderPoghossianetal.2015,
  author    = {Wu, Chunsheng and Bronder, Thomas and Poghossian, Arshak and Werner, Frederik and Sch{\"o}ning, Michael Josef},
  title     = {Label-free detection of DNA using light-addressable potentiometric sensor modified with a positively charged polyelectrolyte layer},
  series = {Nanoscale},
  volume    = {14},
  journal   = {Nanoscale},
  number    = {7},
  publisher = {Royal Society of Chemistry (RSC)},
  address   = {Cambridge},
  doi       = {10.1039/C4NR07225A},
  pages     = {6143 -- 6150},
  year      = {2015},
  abstract  = {A multi-spot (16 spots) light-addressable potentiometric sensor (MLAPS) consisting of an Al-p-Si-SiO2 structure modified with a weak polyelectrolyte layer of PAH (poly(allylamine hydrochloride)) was applied for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge for the first time. To achieve a preferentially flat orientation of DNA strands and thus, to reduce the distance between the DNA charge and MLAPS surface, the negatively charged probe single-stranded DNAs (ssDNA) were electrostatically adsorbed onto the positively charged PAH layer using a simple layer-by-layer (LbL) technique. In this way, more DNA charge can be positioned within the Debye length, yielding a higher sensor signal. The surface potential changes in each spot induced due to the surface modification steps (PAH adsorption, probe ssDNA immobilization, hybridization with complementary target DNA (cDNA), non-specific adsorption of mismatched ssDNA) were determined from the shifts of photocurrent-voltage curves along the voltage axis. A high sensor signal of 83 mV was registered after immobilization of probe ssDNA onto the PAH layer. The hybridization signal increases from 5 mV to 32 mV with increasing the concentration of cDNA from 0.1 nM to 5 μM. In contrast, a small signal of 5 mV was recorded in the case of non-specific adsorption of fully mismatched ssDNA (5 μM). The obtained results demonstrate the potential of the MLAPS in combination with the simple and rapid LbL immobilization technique as a promising platform for the future development of multi-spot light-addressable label-free DNA chips with direct electrical readout.},
  language  = {en}
}
@article{WuPoghossianBronderetal.2016,
  author    = {Wu, Chunsheng and Poghossian, Arshak and Bronder, Thomas and Sch{\"o}ning, Michael Josef},
  title     = {Sensing of double-stranded DNA molecules by their intrinsic molecular charge using the light-addressable potentiometric sensor},
  series = {Sensors and Actuators B: Chemical},
  journal   = {Sensors and Actuators B: Chemical},
  number    = {229},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2016.02.004},
  pages     = {506 -- 512},
  year      = {2016},
  abstract  = {A multi-spot light-addressable potentiometric sensor (LAPS), which belongs to the family of semiconductor field-effect devices, was applied for label-free detection of double-stranded deoxyribonucleic acid (dsDNA) molecules by their intrinsic molecular charge. To reduce the distance between the DNA charge and sensor surface and thus, to enhance the electrostatic coupling between the dsDNA molecules and the LAPS, the negatively charged dsDNA molecules were electrostatically adsorbed onto the gate surface of the LAPS covered with a positively charged weak polyelectrolyte layer of PAH (poly(allylamine hydrochloride)). The surface potential changes in each spot of the LAPS, induced by the layer-by-layer adsorption of a PAH/dsDNA bilayer, were recorded by means of photocurrent-voltage and constant-photocurrent measurements. In addition, the surface morphology of the gate surface before and after consecutive electrostatic adsorption of PAH and dsDNA layers was studied by atomic force microscopy measurements. Moreover, fluorescence microscopy was used to verify the successful adsorption of dsDNA molecules onto the PAH-modified LAPS surface. A high sensor signal of 25 mV was registered after adsorption of 10 nM dsDNA molecules. The lower detection limit is down to 0.1 nM dsDNA. The obtained results demonstrate that the PAH-modified LAPS device provides a convenient and rapid platform for the direct label-free electrical detection of in-solution hybridized dsDNA molecules.},
  language  = {en}
}
@article{WulfhorstDuweMerseburgetal.2016,
  author    = {Wulfhorst, Helene and Duwe, Anna-Maria and Merseburg, Johannes and Tippk{\"o}tter, Nils},
  title     = {Compositional analysis of pretreated (beech) wood using differential scanning calorimetry and multivariate data analysis},
  series = {Tetrahedron},
  volume    = {72},
  journal   = {Tetrahedron},
  number    = {46},
  publisher = {Elsevier},
  address   = {Amsterdam},
  doi       = {10.1016/j.tet.2016.04.029},
  pages     = {7329 -- 7334},
  year      = {2016},
  abstract  = {The composition of plant biomass varies depending on the feedstock and pre-treatment conditions and influences its processing in biorefineries. In order to ensure optimal process conditions, the quantitative proportion of the main polymeric components of the pre-treated biomass has to be determined. Current standard procedures for biomass compositional analysis are complex, the measurements are afflicted with errors and therefore often not comparable. Hence, new powerful analytical methods are urgently required to characterize biomass. In this contribution, Differential Scanning Calorimetry (DSC) was applied in combination with multivariate data analysis (MVA) to detect the cellulose content of the plant biomass pretreated by Liquid Hot Water (LHW) and Organosolv processes under various conditions. Unlike conventional techniques, the developed analytic method enables the accurate quantification of monosaccharide content of the plant biomass without any previous sample preparation. It is easy to handle and avoids errors in sample preparation.},
  language  = {en}
}
@article{XuLueMaetal.2005,
  author    = {Xu, Jung-Ming and L{\"u}, Min and Ma, Meijie and Hellwig, Angelika},
  title     = {Super connectivity of line graphs},
  series = {Information processing letters},
  volume    = {Vol. 94},
  journal   = {Information processing letters},
  number    = {Iss. 4},
  issn      = {1872-6119 (E-Journal); 0020-0190 (Print)},
  pages     = {191 -- 195},
  year      = {2005},
  language  = {en}
}
@article{YangKriechbaumerAlbrachtetal.2015,
  author    = {Yang, Peng-Fei and Kriechbaumer, Andreas and Albracht, Kirsten and Sanno, Maximilian and Ganse, Bergita and Koy, Timmo and Shang, Peng and Br{\"u}ggemann, Gert-Peter and M{\"u}ller, Lars Peter and Rittweger, J{\"o}rn},
  title     = {On the relationship between tibia torsional deformation and regional muscle contractions in habitual human exercises in vivo},
  series = {Journal of Biomechanics},
  volume    = {48},
  journal   = {Journal of Biomechanics},
  number    = {3},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0021-9290},
  doi       = {10.1016/j.jbiomech.2014.12.031},
  pages     = {456 -- 464},
  year      = {2015},
  language  = {en}
}
@article{YangKriechbaumerAlbrachtetal.2014,
  author    = {Yang, Peng-Fei and Kriechbaumer, Andreas and Albracht, Kirsten and Sanno, Maximilian and Ganse, Bergita and Koy, Timmo and Shang, Peng and br{\"u}ggemann, Gert-Peter and M{\"u}ller, Lars Peter and Rittweger, J{\"o}rn},
  title     = {A novel optical approach for assessing in vivo bone segment deformation and its application in muscle-bone relationship studies in humans},
  series = {Journal of Orthopaedic Translation},
  volume    = {2},
  journal   = {Journal of Orthopaedic Translation},
  number    = {4},
  publisher = {Elsevier},
  address   = {Singapore},
  issn      = {2214-0328},
  doi       = {10.1016/j.jot.2014.07.078},
  pages     = {238 -- 238},
  year      = {2014},
  language  = {en}
}
@article{YazdanbakhshSolbachBitz2012,
  author    = {Yazdanbakhsh, Pedram and Solbach, Klaus and Bitz, Andreas},
  title     = {Variable power combiner for RF mode shimming in 7-T MR imaging},
  series = {IEEE Transaction on Biomedical Engineering},
  volume    = {59},
  journal   = {IEEE Transaction on Biomedical Engineering},
  number    = {9},
  publisher = {IEEE},
  address   = {New York},
  issn      = {1558-2531},
  doi       = {10.1109/TBME.2012.2205926},
  pages     = {2549 -- 2557},
  year      = {2012},
  abstract  = {This contribution discusses the utilization of RF power in an MRI system with RF mode shimming which enables the superposition of circularly polarized modes of a transmit RF coil array driven by a Butler matrix. Since the required power for the individual modes can vary widely, mode-shimming can result in a significant underutilization of the total available RF power. A variable power combiner (VPC) is proposed to improve the power utilization: it can be realized as a reconfiguration of the MRI transmit system by the inclusion of one additional matrix network which receives the power from all transmit amplifiers at its input ports and provides any desired (combined) power distribution at its output ports by controlling the phase and amplitude of the amplifiers' input signals. The power distribution at the output ports of the VPC is then fed into the "mode" ports of the coil array Butler matrix in order to superimpose the spatial modes at the highest achievable power utilization. The VPC configuration is compared to the standard configuration of the transmit chain of our MRI system with 8 transmit channels and 16 coils. In realistic scenarios, improved power utilization was achieved from 17\% to 60\% and from 14\% to 55\% for an elliptical phantom and a region of interest in the abdomen, respectively, and an increase of the power utilization of 1 dB for a region of interest in the upper leg. In general, it is found that the VPC allows significant improvement in power utilization when the shimming solution demands only a few modes to be energized, while the technique can yield loss in power utilization in cases with many modes required at high power level.},
  language  = {en}
}
@article{YoshinobuEckenIsmailetal.2001,
  author    = {Yoshinobu, T. and Ecken, H. and Ismail, Md.A.B. and Iwasaki, H. and L{\"u}th, H. and Sch{\"o}ning, Michael Josef},
  title     = {Chemical imaging sensor and its application to biological systems},
  series = {Scaling down in electrochemistry : electrochemical micro- and nanosystem technology ; proceedings of the 3rd International Symposium on Electrochemical Microsystem Technologies, Garmisch-Patenkirchen, Germany, 11 - 15 September 2000 / ed. by J. W. Schultz},
  journal   = {Scaling down in electrochemistry : electrochemical micro- and nanosystem technology ; proceedings of the 3rd International Symposium on Electrochemical Microsystem Technologies, Garmisch-Patenkirchen, Germany, 11 - 15 September 2000 / ed. by J. W. Schultz},
  publisher = {Elsevier [u.a.]},
  address   = {Amsterdam [u.a.]},
  isbn      = {0-08-044014-2},
  pages     = {259 -- 263},
  year      = {2001},
  language  = {en}
}
@article{YoshinobuEckenPoghossianetal.2001,
  author    = {Yoshinobu, T. and Ecken, H. and Poghossian, Arshak and L{\"u}th, H. and Iwasaki, H. and Sch{\"o}ning, Michael Josef},
  title     = {Alternative sensor materials for light-addressable potentiometric sensors},
  series = {Sensors and Actuators B. 76 (2001), H. 1-3},
  journal   = {Sensors and Actuators B. 76 (2001), H. 1-3},
  isbn      = {0925-4005},
  pages     = {388 -- 392},
  year      = {2001},
  language  = {en}
}
@article{YoshinobuEckenPoghossianetal.2001,
  author    = {Yoshinobu, T. and Ecken, H. and Poghossian, Arshak and Simonis, A. and Iwasaki, H. and L{\"u}th, H. and Sch{\"o}ning, Michael Josef},
  title     = {Constant-current-mode LAPS (CLAPS) for the detection of penicillin},
  series = {Electroanalysis. 13 (2001), H. 8-9},
  journal   = {Electroanalysis. 13 (2001), H. 8-9},
  isbn      = {1040-0397},
  pages     = {733 -- 736},
  year      = {2001},
  language  = {en}
}
@article{YoshinobuErmelenkoMourzinaetal.2003,
  author    = {Yoshinobu, T. and Ermelenko, Y. and Mourzina, Y. and Sch{\"o}ning, Michael Josef and Iwasaki, H. and Vlasov, Y.},
  title     = {Multi-component analysis based on the light-addressable potentiometric sensor (LAPS)},
  series = {Proceedings : 11th international conference Sensor 2003; 13 - 15 May 2003, Exhibition Centre Nuremberg, Germany},
  journal   = {Proceedings : 11th international conference Sensor 2003; 13 - 15 May 2003, Exhibition Centre Nuremberg, Germany},
  publisher = {AMA Service},
  address   = {Wunstorf},
  pages     = {141 -- 144},
  year      = {2003},
  language  = {en}
}
@article{YoshinobuIwasakiUietal.2005,
  author    = {Yoshinobu, T. and Iwasaki, H. and Ui, Y. and Furuichi, K. and Ermelenko, Y. and Mourzina, Y. and Wagner, Torsten and N{\"a}ther, Niko and Sch{\"o}ning, Michael Josef},
  title     = {The light-addressable potentiometric sensor for multi-ion sensing and imaging},
  series = {Methods. 37 (2005), H. 1},
  journal   = {Methods. 37 (2005), H. 1},
  isbn      = {1046-2023},
  pages     = {99 -- 102},
  year      = {2005},
  language  = {en}
}
@article{YoshinobuSchoeningFingeretal.2004,
  author    = {Yoshinobu, T. and Sch{\"o}ning, Michael Josef and Finger, F. and Moritz, W. and Iwasaki, H.},
  title     = {Fabrication of thin-film LAPS with amorphous silicon},
  series = {Sensors. 4 (2004), H. 10},
  journal   = {Sensors. 4 (2004), H. 10},
  isbn      = {1424-8220},
  pages     = {163 -- 169},
  year      = {2004},
  language  = {en}
}
@article{YoshinobuSchoeningOttoetal.2003,
  author    = {Yoshinobu, T. and Sch{\"o}ning, Michael Josef and Otto, R. and Furuichi, K. and Mourzina, Y. and Ermelenko, Y. and Iwasaki, H.},
  title     = {Portable light-addressable potentiometric sensor (LAPS) for multisensor applications},
  series = {Sensors and Actuators B. 95 (2003), H. 1-3},
  journal   = {Sensors and Actuators B. 95 (2003), H. 1-3},
  isbn      = {0925-4005},
  pages     = {352 -- 356},
  year      = {2003},
  language  = {en}
}
@article{YoshinobuSchoeningOttoetal.2002,
  author    = {Yoshinobu, T. and Sch{\"o}ning, Michael Josef and Otto, R. and Furuichi, K. and Mourzina, Yu and Ermelenko, Yu and Iwasaki, I.},
  title     = {Portable light-addressable potentiometric sensor (LAPS) for multisensor applications},
  series = {Book of abstracts / ed. by J. Saneistr.},
  journal   = {Book of abstracts / ed. by J. Saneistr.},
  publisher = {Czech Technical University, Faculty of Electrical Engineering, Department of Measurement},
  address   = {Prague},
  isbn      = {80-01-02576-4},
  pages     = {898 -- 901},
  year      = {2002},
  language  = {en}
}
@article{YoshinobuUiIwasakietal.2004,
  author    = {Yoshinobu, T. and Ui, Y. and Iwasaki, H. and N{\"a}ther, Niko and Koudelka-Hep, M. and Sch{\"o}ning, Michael Josef},
  title     = {Potentiometric imaging in a microfluidic channel},
  series = {Biomedizinische Technik. 49 (2004), H. 2},
  journal   = {Biomedizinische Technik. 49 (2004), H. 2},
  isbn      = {0932-4666},
  pages     = {998 -- 999},
  year      = {2004},
  language  = {en}
}
@article{YoshinobuYasuhitoIwasakietal.2004,
  author    = {Yoshinobu, T. and Yasuhito, U. and Iwasaki, H. and N{\"a}ther, Niko and Sch{\"o}ning, Michael Josef and Koudelka-Hep, M.},
  title     = {Applications of the light-addressable potentiometric sensor to microfluidic devices},
  series = {Digest of technical papers : September 12 - 15, 2004, Rome, Italy, Pontificia Universitas Sancto Thoma Aquinate in Urbe / [conference chairperson: C. Di Natale].},
  journal   = {Digest of technical papers : September 12 - 15, 2004, Rome, Italy, Pontificia Universitas Sancto Thoma Aquinate in Urbe / [conference chairperson: C. Di Natale].},
  address   = {Roma},
  isbn      = {88-7621-282-5},
  pages     = {434 -- 437},
  year      = {2004},
  language  = {en}
}
@article{YoshinobuMiyamotoWagneretal.2015,
  author    = {Yoshinobu, Tatsuo and Miyamoto, Ko-ichiro and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Recent developments of chemical imaging sensor systems based on the principle of the light-addressable potentiometric sensor},
  series = {Sensors and actuators B: Chemical},
  volume    = {207, Part B},
  journal   = {Sensors and actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-3077 (E-Journal); 0925-4005 (Print)},
  doi       = {10.1016/j.snb.2014.09.002},
  pages     = {926 -- 932},
  year      = {2015},
  abstract  = {The light-addressable potentiometric sensor (LAPS) is an electrochemical sensor with a field-effect structure to detect the variation of the Nernst potential at its sensor surface, the measured area on which is defined by illumination. Thanks to this light-addressability, the LAPS can be applied to chemical imaging sensor systems, which can visualize the two-dimensional distribution of a particular target ion on the sensor surface. Chemical imaging sensor systems are expected to be useful for analysis of reaction and diffusion in various electrochemical and biological samples. Recent developments of LAPS-based chemical imaging sensor systems, in terms of the spatial resolution, measurement speed, image quality, miniaturization and integration with microfluidic devices, are summarized and discussed.},
  language  = {en}
}
@article{YoshinobuMiyamotoWagneretal.2024,
  author    = {Yoshinobu, Tatsuo and Miyamoto, Ko-ichiro and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Field-effect sensors combined with the scanned light pulse technique: from artificial olfactory images to chemical imaging technologies},
  series = {Chemosensors},
  volume    = {12},
  journal   = {Chemosensors},
  number    = {2},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2227-9040},
  doi       = {10.3390/chemosensors12020020},
  pages     = {Artikel 20},
  year      = {2024},
  abstract  = {The artificial olfactory image was proposed by Lundstr{\"o}m et al. in 1991 as a new strategy for an electronic nose system which generated a two-dimensional mapping to be interpreted as a fingerprint of the detected gas species. The potential distribution generated by the catalytic metals integrated into a semiconductor field-effect structure was read as a photocurrent signal generated by scanning light pulses. The impact of the proposed technology spread beyond gas sensing, inspiring the development of various imaging modalities based on the light addressing of field-effect structures to obtain spatial maps of pH distribution, ions, molecules, and impedance, and these modalities have been applied in both biological and non-biological systems. These light-addressing technologies have been further developed to realize the position control of a faradaic current on the electrode surface for localized electrochemical reactions and amperometric measurements, as well as the actuation of liquids in microfluidic devices.},
  language  = {en}
}
@article{YoshinobuMiyamotoWerneretal.2017,
  author    = {Yoshinobu, Tatsuo and Miyamoto, Ko-ichiro and Werner, Frederik and Poghossian, Arshak and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Light-addressable potentiometric sensors for quantitative spatial imaging of chemical species},
  series = {Annual Review of Analytical Chemistry},
  volume    = {10},
  journal   = {Annual Review of Analytical Chemistry},
  publisher = {Annual Reviews},
  address   = {Palo Alto, Calif.},
  issn      = {1936-1327},
  doi       = {10.1146/annurev-anchem-061516-045158},
  pages     = {225 -- 246},
  year      = {2017},
  abstract  = {A light-addressable potentiometric sensor (LAPS) is a semiconductor-based chemical sensor, in which a measurement site on the sensing surface is defined by illumination. This light addressability can be applied to visualize the spatial distribution of pH or the concentration of a specific chemical species, with potential applications in the fields of chemistry, materials science, biology, and medicine. In this review, the features of this chemical imaging sensor technology are compared with those of other technologies. Instrumentation, principles of operation, and various measurement modes of chemical imaging sensor systems are described. The review discusses and summarizes state-of-the-art technologies, especially with regard to the spatial resolution and measurement speed; for example, a high spatial resolution in a submicron range and a readout speed in the range of several tens of thousands of pixels per second have been achieved with the LAPS. The possibility of combining this technology with microfluidic devices and other potential future developments are discussed.},
  language  = {en}
}
@article{YoshinobuMoritzFingeretal.2006,
  author    = {Yoshinobu, Tatsuo and Moritz, Werner and Finger, Friedhelm and Sch{\"o}ning, Michael Josef},
  title     = {Application of thin-film amorphous silicon to chemical imaging},
  series = {Nanostructured materials and hybrid composites for gas sensors and biomedical applications : symposium held April 18-20, 2006, San Francisco , California, U.S.A.},
  journal   = {Nanostructured materials and hybrid composites for gas sensors and biomedical applications : symposium held April 18-20, 2006, San Francisco , California, U.S.A.},
  number    = {Paper 0910-A-20-01},
  editor    = {Comini, Elisabetta},
  isbn      = {9781558998711},
  pages     = {1 -- 10},
  year      = {2006},
  language  = {en}
}
@article{YoshinobuSchoening2021,
  author    = {Yoshinobu, Tatsuo and Sch{\"o}ning, Michael Josef},
  title     = {Light-addressable potentiometric sensors (LAPS) for cell monitoring and biosensing},
  series = {Current Opinion in Electrochemistry},
  journal   = {Current Opinion in Electrochemistry},
  number    = {In Press, Journal Pre-proof},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2451-9103},
  doi       = {10.1016/j.coelec.2021.100727},
  year      = {2021},
  language  = {en}
}
@article{ZangeSchopenAlbrachtetal.2017,
  author    = {Zange, Jochen and Schopen, Kathrin and Albracht, Kirsten and Gerlach, Darius A. and Frings-Meuthen, Petra and Maffiuletti, Nicola A. and Bloch, Wilhelm and Rittweger, J{\"o}rn},
  title     = {Using the Hephaistos orthotic device to study countermeasure effectiveness of neuromuscular electrical stimulation and dietary lupin protein supplementation, a randomised controlled trial},
  series = {Plos one},
  volume    = {12},
  journal   = {Plos one},
  number    = {2},
  doi       = {10.1371/journal.pone.0171562},
  year      = {2017},
  language  = {en}
}
@article{Zastrow1985,
  author    = {Zastrow, Udo},
  title     = {On the complete system of fundamental solutions for anisotropic slices and slabs: A comparison by use of the slab analogy},
  series = {Journal of Elasticity. 15 (1985), H. 3},
  journal   = {Journal of Elasticity. 15 (1985), H. 3},
  isbn      = {1573-2681},
  pages     = {293 -- 318},
  year      = {1985},
  language  = {en}
}
@article{Zastrow1985,
  author    = {Zastrow, Udo},
  title     = {Basic geometrical singularities in plane-elasticity and plate-bending problems},
  series = {International Journal of Solids and Structures. 21 (1985), H. 10},
  journal   = {International Journal of Solids and Structures. 21 (1985), H. 10},
  isbn      = {0020-7683},
  pages     = {1047 -- 1067},
  year      = {1985},
  language  = {en}
}
@article{Zastrow1985,
  author    = {Zastrow, Udo},
  title     = {Numerical plane stress analysis by integral equations based on the singularity method},
  series = {SM archives . 10 (1985)},
  journal   = {SM archives . 10 (1985)},
  isbn      = {0376-7426},
  pages     = {113 -- 128},
  year      = {1985},
  language  = {en}
}
@article{Zastrow1982,
  author    = {Zastrow, Udo},
  title     = {Solution of plane anisotropic elastostatical boundary value problems by singular integral equations},
  series = {Acta Mechanica. 44 (1982), H. 1-2},
  journal   = {Acta Mechanica. 44 (1982), H. 1-2},
  isbn      = {1619-6937},
  pages     = {59 -- 71},
  year      = {1982},
  language  = {en}
}
@article{Zastrow1985,
  author    = {Zastrow, Udo},
  title     = {On the formulation of the fundamental solutions for orthotropic plane elasticity},
  series = {Acta Mechanica. 57 (1985), H. 3-4},
  journal   = {Acta Mechanica. 57 (1985), H. 3-4},
  isbn      = {1619-6937},
  pages     = {113 -- 122},
  year      = {1985},
  language  = {en}
}
@article{ZastrowHackl1988,
  author    = {Zastrow, Udo and Hackl, Klaus},
  title     = {On the existence, uniqueness and completeness of displacements and stress functions in linear elasticity / Hackl, Klaus ; Zastrow, Udo},
  series = {Journal of Elasticity. 19 (1988), H. 1},
  journal   = {Journal of Elasticity. 19 (1988), H. 1},
  isbn      = {1573-2681},
  pages     = {3 -- 23},
  year      = {1988},
  language  = {en}
}
@article{ZastrowPanagiotopoulos1979,
  author    = {Zastrow, Udo and Panagiotopoulos, P. D.},
  title     = {An integral "Equation" approach to the unilateral contact problem},
  series = {ZAMM - Zeitschrift f{\"u}r angewandte Mathematik und Mechanik. 59 (1979), H. 8},
  journal   = {ZAMM - Zeitschrift f{\"u}r angewandte Mathematik und Mechanik. 59 (1979), H. 8},
  isbn      = {1521-4001},
  pages     = {392 -- 393},
  year      = {1979},
  language  = {en}
}
@article{ZastrowRieder1980,
  author    = {Zastrow, Udo and Rieder, G.},
  title     = {Bracketing eigenvalues of an oscillating elastic body by integral equations},
  series = {Bracketing of eigenfrequencies of continous structures : Euromech Colloquium, no. 112, M{\´a}traf{\"u}red (Hungary), 21 - 23 February, 1979 / ed. by {\`A}. Bosznay},
  journal   = {Bracketing of eigenfrequencies of continous structures : Euromech Colloquium, no. 112, M{\´a}traf{\"u}red (Hungary), 21 - 23 February, 1979 / ed. by {\`A}. Bosznay},
  publisher = {Akad. Kiad{\´o}},
  address   = {Budapest},
  isbn      = {963-05-2625-5},
  pages     = {421 -- 434},
  year      = {1980},
  language  = {en}
}
@article{ZatkoDubeckyBohaceketal.2004,
  author    = {Zatko, B. and Dubeck{\´y}, F. and Bohacek, P. and Gombia, E. and Frigeri, P. and Mosca, R. and Franchi, S. and Huarn, J. and Nescas, V. and Sekacova, M. and F{\"o}rster, Arnold and Kordos, P.},
  title     = {On the spectrometric performance limit of radiation detectors based on semi-insulating GaAs},
  series = {Nuclear instruments and methods in physics research, Section A. 531 (2004), H. 1-2},
  journal   = {Nuclear instruments and methods in physics research, Section A. 531 (2004), H. 1-2},
  isbn      = {0168-9002},
  pages     = {111 -- 120},
  year      = {2004},
  language  = {en}
}
@article{ZerlinDigelStadleretal.2007,
  author    = {Zerlin, Kay and Digel, Ilya and Stadler, Andreas M. and B{\"u}ldt, Georg and Zaccai, Guiseppe and Artmann, Gerhard},
  title     = {Dynamics and interactions of hemoglobin in human red blood cells and concentrated hemoglobin solutions},
  series = {Regenerative medicine. 2 (2007), H. 5},
  journal   = {Regenerative medicine. 2 (2007), H. 5},
  isbn      = {1746-0751},
  pages     = {573 -- 573},
  year      = {2007},
  language  = {en}
}
@article{ZerlinKasischkeDigeletal.2007,
  author    = {Zerlin, Kay and Kasischke, Nicole and Digel, Ilya and Maggakis-Kelemen, Christina and Temiz Artmann, Ayseg{\"u}l and Porst, Dariusz and Kayser, Peter and Linder, Peter and Artmann, Gerhard},
  title     = {Structural transition temperature of hemoglobins correlates with species' body temperature},
  series = {European Biophysics Journal. 37 (2007), H. 1},
  journal   = {European Biophysics Journal. 37 (2007), H. 1},
  isbn      = {1432-1017},
  pages     = {1 -- 10},
  year      = {2007},
  language  = {en}
}
@article{ZhangValeroBungetal.2018,
  author    = {Zhang, G. and Valero, Daniel and Bung, Daniel Bernhard and Chanson, H.},
  title     = {On the estimation of free-surface turbulence using ultrasonic sensors},
  series = {Flow Measurement and Instrumentation},
  volume    = {60},
  journal   = {Flow Measurement and Instrumentation},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0955-5986},
  doi       = {10.1016/j.flowmeasinst.2018.02.009},
  pages     = {171 -- 184},
  year      = {2018},
  abstract  = {Accurate determination of free-surface dynamics has attracted much research attention during the past decade and has important applications in many environmental and water related areas. In this study, the free-surface dynamics in several turbulent flows commonly found in nature were investigated using a synchronised setup consisting of an ultrasonic sensor and a high-speed video camera. Basic sensor capabilities were examined in dry conditions to allow for a better characterisation of the present sensor model. The ultrasonic sensor was found to adequately reproduce free-surface dynamics up to the second order, especially in two-dimensional scenarios with the most energetic modes in the low frequency range. The sensor frequency response was satisfactory in the sub-20 Hz band, and its signal quality may be further improved by low-pass filtering prior to digitisation. The application of the USS to characterise entrapped air in high-velocity flows is also discussed.},
  language  = {en}
}
@article{ZhangHeimbachScheeretal.2016,
  author    = {Zhang, Jin and Heimbach, Tycho and Scheer, Nico and Barve, Avantika and Li, Wenkui and Lin, Wen and He, Handan},
  title     = {Clinical Exposure Boost Predictions by Integrating Cytochrome P450 3A4-Humanized Mouse Studies With PBPK Modeling},
  series = {Journal of Pharmaceutical Sciences},
  volume    = {Volume 105},
  journal   = {Journal of Pharmaceutical Sciences},
  number    = {Issue 4},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0022-3549},
  doi       = {doi.org/10.1016/j.xphs.2016.01.021},
  pages     = {1398 -- 1404},
  year      = {2016},
  abstract  = {NVS123 is a poorly water-soluble protease 56 inhibitor in clinical development. Data from in vitro hepatocyte studies suggested that NVS123 is mainly metabolized by CYP3A4. As a consequence of limited solubility, NVS123 therapeutic plasma exposures could not be achieved even with high doses and optimized formulations. One approach to overcome NVS123 developability issues was to increase plasma exposure by coadministrating it with an inhibitor of CYP3A4 such as ritonavir. A clinical boost effect was predicted by using physiologically based pharmacokinetic (PBPK) modeling. However, initial boost predictions lacked sufficient confidence because a key parameter, fraction of drug metabolized by CYP3A4 (ƒₘCYP3A4), could not be estimated with accuracy on account of disconnects between in vitro and in vivo preclinical data. To accurately estimate ƒₘCYP3A4 in human, an in vivo boost effect study was conducted using CYP3A4-humanized mouse model which showed a 33- to 56-fold exposure boost effect. Using a top-down approach, human ƒₘCYP3A4 for NVS123 was estimated to be very high and included in the human PBPK modeling to support subsequent clinical study design. The combined use of the in vivo boost study in CYP3A4-humanized mouse model mice along with PBPK modeling accurately predicted the clinical outcome and identified a significant NVS123 exposure boost (∼42-fold increase) with ritonavir.},
  language  = {en}
}
@article{ZhantlessovaSavitskayaKistaubayevaetal.2022,
  author    = {Zhantlessova, Sirina and Savitskaya, Irina and Kistaubayeva, Aida and Ignatova, Ludmila and Talipova, Aizhan and Pogrebnjak, Alexander and Digel, Ilya},
  title     = {Advanced "Green" prebiotic composite of bacterial cellulose/pullulan based on synthetic biology-powered microbial coculture strategy},
  series = {Polymers},
  volume    = {14},
  journal   = {Polymers},
  number    = {15},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2073-4360},
  doi       = {10.3390/polym14153224},
  pages     = {Artikel 3224},
  year      = {2022},
  abstract  = {Bacterial cellulose (BC) is a biopolymer produced by different microorganisms, but in biotechnological practice, Komagataeibacter xylinus is used. The micro- and nanofibrillar structure of BC, which forms many different-sized pores, creates prerequisites for the introduction of other polymers into it, including those synthesized by other microorganisms. The study aims to develop a cocultivation system of BC and prebiotic producers to obtain BC-based composite material with prebiotic activity. In this study, pullulan (PUL) was found to stimulate the growth of the probiotic strain Lactobacillus rhamnosus GG better than the other microbial polysaccharides gellan and xanthan. BC/PUL biocomposite with prebiotic properties was obtained by cocultivation of Komagataeibacter xylinus and Aureobasidium pullulans, BC and PUL producers respectively, on molasses medium. The inclusion of PUL in BC is proved gravimetrically by scanning electron microscopy and by Fourier transformed infrared spectroscopy. Cocultivation demonstrated a composite effect on the aggregation and binding of BC fibers, which led to a significant improvement in mechanical properties. The developed approach for "grafting" of prebiotic activity on BC allows preparation of environmentally friendly composites of better quality.},
  language  = {en}
}
@article{ZhenLiangStaatetal.2024,
  author    = {Zhen, Manghao and Liang, Yunpei and Staat, Manfred and Li, Quanqui and Li, Jianbo},
  title     = {Discontinuous fracture behaviors and constitutive model of sandstone specimens containing non-parallel prefabricated fissures under uniaxial compression},
  series = {Theoretical and Applied Fracture Mechanics},
  volume    = {131},
  journal   = {Theoretical and Applied Fracture Mechanics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0167-8442},
  doi       = {10.1016/j.tafmec.2024.104373},
  pages     = {Artikel 104373},
  year      = {2024},
  abstract  = {The deformation and damage laws of non-homogeneous irregular structural planes in rocks are the basis for studying the stability of rock engineering. To investigate the damage characteristics of rock containing non-parallel fissures, uniaxial compression tests and numerical simulations were conducted on sandstone specimens containing three non-parallel fissures inclined at 0°, 45° and 90° in this study. The characteristics of crack initiation and crack evolution of fissures with different inclinations were analyzed. A constitutive model for the discontinuous fractures of fissured sandstone was proposed. The results show that the fracture behaviors of fissured sandstone specimens are discontinuous. The stress-strain curves are non-smooth and can be divided into nonlinear crack closure stage, linear elastic stage, plastic stage and brittle failure stage, of which the plastic stage contains discontinuous stress drops. During the uniaxial compression test, the middle or ends of 0° fissures were the first to crack compared to 45° and 90° fissures. The end with small distance between 0° and 45° fissures cracked first, and the end with large distance cracked later. After the final failure, 0° fissures in all specimens were fractured, while 45° and 90° fissures were not necessarily fractured. Numerical simulation results show that the concentration of compressive stress at the tips of 0°, 45° and 90° fissures, as well as the concentration of tensile stress on both sides, decreased with the increase of the inclination angle. A constitutive model for the discontinuous fractures of fissured sandstone specimens was derived by combining the logistic model and damage mechanic theory. This model can well describe the discontinuous drops of stress and agrees well with the whole processes of the stress-strain curves of the fissured sandstone specimens.},
  language  = {en}
}
@article{ZhubanovaAknazarovMansurovetal.2010,
  author    = {Zhubanova, Azhar A. and Aknazarov, S. K. and Mansurov, Zulkhair and Digel, Ilya and Kozhalakova, A. A. and Akimbekov, Nuraly S. and O'Heras, Carlos and Tazhibayeva, S. and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l},
  title     = {Adsorption of bacterial Lipopolysaccharides and blood plasma proteins on modified carbonized materials},
  year      = {2010},
  abstract  = {Bacterial lipopolysaccharides (endotoxins) show strong biological effects at very low concentrations in human beings and many animals when entering the blood stream. These include affecting structure and function of organs and cells, changing metabolic functions, raising body temperature, triggering the coagulation cascade, modifying hemodynamics and causing septic shock. Because of this toxicity, the removal of even minute amounts is essential for safe parenteral administration of drugs and also for septic shock patients' care. The absence of a general method for endotoxin removal from liquid interfaces urgently requires finding new methods and materials to overcome this gap. Nanostructured carbonized plant parts is a promising material that showed good adsorption properties due to its vast pore network and high surface area. The aim of this study was comparative measurement of endotoxin- and blood proteins-related adsorption rate and adsorption capacity for different carboneous materials produced at different temperatures and under different surface modifications. As a main surface modificator, positively cbarged polymer, polyethileneimine (PEl) was used. Activated carbon materials showed good adsorption properties for LPS and some proteins used in the experiments. During the batch experiments, several techniques (dust removal, autoclaving) were used and optimized for improving the material's adsorption behavior. Also, with the results obtained it was possible to differentiate the materials according to their adsorption capacity and kinetic characteristics. Modification of the surface apparently has not affected hemoglobin binding to the adsorbent's surface. Obtained adsorption isotherms can be used as a powerful tool for designing of future column-based setups for blood purification from LPS, which is especially important for septic shock treatment.},
  subject      = {Kohlenstofffaser},
  language  = {en}
}
@article{ZhubanovaDigelNojimaetal.2007,
  author    = {Zhubanova, Azhar A. and Digel, Ilya and Nojima, H. and Artmann, Gerhard},
  title     = {The use of bactericidal effects of cluster ions generated by plasma in medical biotechnology},
  year      = {2007},
  abstract  = {The most of conventional methods of air purification use the power of a fan to draw in air and pass it through a filter. The problem of bacterial contamination of inner parts of such a type of air conditioners in some cases draws attention towards alternative air-cleaning systems. Some manufacturers offer to use the ozone's bactericidal and deodorizing effects, but the wide spreading of such systems is restricted by the fact that toxic effects of ozone in respect of human beings are well known. In 2000 Sharp Inc. introduced "Plasma Cluster Ions (PCI)" air purification technology, which uses plasma discharge to generate cluster ions (I 0-14 ). This technology has been developed for those customers that are conscious about health and hygiene. In our experiments, we focused on some principal aspects of plasma-generated ions application - time-dependency and irreversibility of bactericidal action, spatial and kinetic characteristics of emitted cluster particles, their chemical targets in the microbial cells.},
  subject      = {Clusterion},
  language  = {en}
}
@article{Ziemons1991,
  author    = {Ziemons, Karl},
  title     = {Comparison of forward hadrons produced in muon interactions on nuclear targets and deuterium},
  series = {Zeitschrift f{\"u}r Physik C Particles and Fields},
  volume    = {52},
  journal   = {Zeitschrift f{\"u}r Physik C Particles and Fields},
  number    = {1},
  isbn      = {1431-5858},
  pages     = {1 -- 11},
  year      = {1991},
  abstract  = {Differential multiplicities of forward produced hadrons in deep inelastic muon scattering on nuclear targets have been compared with those from deuterium. The ratios are observed to increase towards unity as the virtual photon energy increases with no significant dependence on the other muon kinematic variables. The hadron transverse momentum distribution is observed to be broadened in nuclear targets. The dependence on the remaining hadron variables is investigated and the results are discussed in the framework of intranuclear interaction models and in the context of the EMC effect.},
  language  = {en}
}
@article{Ziemons1992,
  author    = {Ziemons, Karl},
  title     = {Muoproduction of J/ψ and the gluon distribution of the nucleon},
  series = {Zeitschrift f{\"u}r Physik C Particles and Fields},
  volume    = {56},
  journal   = {Zeitschrift f{\"u}r Physik C Particles and Fields},
  number    = {1},
  isbn      = {1431-5858},
  pages     = {21 -- 28},
  year      = {1992},
  abstract  = {Measurements are presented of the inclusive distributions of the J/Ψ meson produced by muons of energy 200 GeV from an ammonia target. The gluon distribution of the nucleon has been derived from the data in the range 0.04<x<0.36 using a technique based on the colour singlet model. An arbitrary normalisation factor is required to obtain a reasonable integral of the gluon distribution. Some comments are made on the use of J/Ψ productionby virtual photons to extract the gluon distribution at HERA.},
  language  = {en}
}
@article{Ziemons1993,
  author    = {Ziemons, Karl},
  title     = {A measurement of the ratio of the nucleon structure function in copper and deuterium},
  series = {Zeitschrift f{\"u}r Physik C Particles and Fields},
  volume    = {57},
  journal   = {Zeitschrift f{\"u}r Physik C Particles and Fields},
  number    = {2},
  isbn      = {1431-5858},
  pages     = {211 -- 218},
  year      = {1993},
  abstract  = {Results are presented on the ratios of the nucleon structure function in copper to deuterium from two separate experiments. The data confirm that the nucleon structure function,F 2, is different for bound nucleons than for the quasi-free ones in the deuteron. The redistribution in the fraction of the nucleon's momentum carried by quarks is investigated and it is found that the data are compatible with no integral loss of quark momenta due to nuclear effects.},
  language  = {en}
}
@article{Ziemons1987,
  author    = {Ziemons, Karl},
  title     = {Jet production and fragmentation properties in deep inelastic muon scattering},
  series = {Zeitschrift f{\"u}r Physik C : Particles and Fields},
  volume    = {36},
  journal   = {Zeitschrift f{\"u}r Physik C : Particles and Fields},
  number    = {4},
  isbn      = {0170-9739},
  pages     = {527 -- 543},
  year      = {1987},
  language  = {en}
}
@article{Ziemons1988,
  author    = {Ziemons, Karl},
  title     = {A measurement of the spin asymmetry of the structure function g1 in deep inelastic muon-proton scattering},
  series = {Physics Letters B},
  volume    = {206},
  journal   = {Physics Letters B},
  number    = {2},
  isbn      = {0370-2693},
  pages     = {364 -- 370},
  year      = {1988},
  abstract  = {The spin asymmetry in deep inelastic scattering of longitudinally polarised muons by longitudinally polarised protons has been measured over a large x range (0.01<x<0.7). The spin-dependent structure function g1(x) for the proton has been determined and its integral over x found to be 0.114±0.012±0.026, in disagreement with the Ellis-Jaffe sum rule. Assuming the validity of the Bjorken sum rule, this result implies a significant negative value for the integral of g1 for the neutron. These values for the integrals of g1 lead to the conclusion that the total quark spin constitutes a rather small fraction of the spin of the nucleon.},
  language  = {en}
}
@article{Ziemons1989,
  author    = {Ziemons, Karl},
  title     = {An investigation of the spin structure of the proton in deep inelastic scattering of polarised muons and polarised protons},
  series = {Nuclear Physics B},
  volume    = {328},
  journal   = {Nuclear Physics B},
  number    = {1},
  isbn      = {0550-3213},
  pages     = {1 -- 35},
  year      = {1989},
  abstract  = {The spin asymmetry in deep inelastic scattering of longitudinally polarised muons by longitudinally polarised protons has been measured in the range 0.01<×<0.7. The spin dependent structure function g1(x) for the proton has been determined and, combining the data with earlier SLAC measurements, its integral over x found to be 0.126±0.010(stat.)±0.015(syst.), in disagreement with the Ellis-Jaffe sum rule. Assuming the validity of the Biorken sum rule, this result implies a significant negative value for the integral of g1 for the neutron. These integrals lead to the conclusion, in the na{\"i}ve quark parton model, that the total quark spin constitutes a rather small fraction of the spin of the nucleon. Results are also presented on the asymmetries in inclusive hadron production which are consistent with the above picture.},
  language  = {en}
}