@inproceedings{WiesenEngemannLimpertetal.2018, author = {Wiesen, Patrick and Engemann, Heiko and Limpert, Nicolas and Kallweit, Stephan}, title = {Learning by Doing - Mobile Robotics in the FH Aachen ROS Summer School}, series = {European Robotics Forum 2018, TRROS18 Workshop}, booktitle = {European Robotics Forum 2018, TRROS18 Workshop}, pages = {47 -- 58}, year = {2018}, language = {en} } @article{WilsonDickieSchreiteretal.2018, author = {Wilson, C. E. and Dickie, A. P. and Schreiter, K. and Wehr, R. and Wilson, E. M. and Bial, J. and Scheer, Nico and Wilson, I. D. and Riley, R. J.}, title = {The pharmacokinetics and metabolism of diclofenac in chimeric humanized and murinized FRG mice}, series = {Archives of Toxicology}, volume = {92}, journal = {Archives of Toxicology}, number = {6}, publisher = {Springer}, issn = {1432-0738}, doi = {10.1007/s00204-018-2212-1}, pages = {1953 -- 1967}, year = {2018}, abstract = {The pharmacokinetics of diclofenac were investigated following single oral doses of 10 mg/kg to chimeric liver humanized and murinized FRG and C57BL/6 mice. In addition, the metabolism and excretion were investigated in chimeric liver humanized and murinized FRG mice. Diclofenac reached maximum blood concentrations of 2.43 ± 0.9 µg/mL (n = 3) at 0.25 h post-dose with an AUCinf of 3.67 µg h/mL and an effective half-life of 0.86 h (n = 2). In the murinized animals, maximum blood concentrations were determined as 3.86 ± 2.31 µg/mL at 0.25 h post-dose with an AUCinf of 4.94 ± 2.93 µg h/mL and a half-life of 0.52 ± 0.03 h (n = 3). In C57BL/6J mice, mean peak blood concentrations of 2.31 ± 0.53 µg/mL were seen 0.25 h post-dose with a mean AUCinf of 2.10 ± 0.49 µg h/mL and a half-life of 0.51 ± 0.49 h (n = 3). Analysis of blood indicated only trace quantities of drug-related material in chimeric humanized and murinized FRG mice. Metabolic profiling of urine, bile and faecal extracts revealed a complex pattern of metabolites for both humanized and murinized animals with, in addition to unchanged parent drug, a variety of hydroxylated and conjugated metabolites detected. The profiles in humanized mice were different to those of both murinized and wild-type animals, e.g., a higher proportion of the dose was detected in the form of acyl glucuronide metabolites and much reduced amounts as taurine conjugates. Comparison of the metabolic profiles obtained from the present study with previously published data from C57BL/6J mice and humans revealed a greater, though not complete, match between chimeric humanized mice and humans, such that the liver humanized FRG model may represent a model for assessing the biotransformation of such compounds in humans.}, language = {en} } @article{Wollert2018, author = {Wollert, J{\"o}rg}, title = {TSN - Schluss mit dem Feldbuskrieg?}, series = {Design \& Elektronik}, journal = {Design \& Elektronik}, number = {3}, publisher = {WEKA-Fachmedien}, address = {M{\"u}nchen}, issn = {0933-8667}, pages = {26 -- 31}, year = {2018}, language = {de} } @article{Wollert2018, author = {Wollert, J{\"o}rg}, title = {Echtzeit-Ethernet - Basis f{\"u}r Industrie 4.0}, series = {Design \& Elektronik}, journal = {Design \& Elektronik}, publisher = {WEKA-Fachmedien}, address = {M{\"u}nchen}, isbn = {0933-8667}, year = {2018}, language = {de} } @incollection{YoshinobuKrauseMiyamotoetal.2018, author = {Yoshinobu, Tatsuo and Krause, Steffi and Miyamoto, Ko-ichiro and Werner, Frederik and Poghossian, Arshak and Wagner, Torsten and Sch{\"o}ning, Michael Josef}, title = {(Bio-)chemical Sensing and Imaging by LAPS and SPIM}, series = {Label-free biosensing: advanced materials, devices and applications}, booktitle = {Label-free biosensing: advanced materials, devices and applications}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-75219-8}, pages = {103 -- 132}, year = {2018}, abstract = {The light-addressable potentiometric sensor (LAPS) and scanning photo-induced impedance microscopy (SPIM) are two closely related methods to visualise the distributions of chemical species and impedance, respectively, at the interface between the sensing surface and the sample solution. They both have the same field-effect structure based on a semiconductor, which allows spatially resolved and label-free measurement of chemical species and impedance in the form of a photocurrent signal generated by a scanning light beam. In this article, the principles and various operation modes of LAPS and SPIM, functionalisation of the sensing surface for measuring various species, LAPS-based chemical imaging and high-resolution sensors based on silicon-on-sapphire substrates are described and discussed, focusing on their technical details and prospective applications.}, language = {en} } @article{ZhangValeroBungetal.2018, author = {Zhang, G. and Valero, Daniel and Bung, Daniel Bernhard and Chanson, H.}, title = {On the estimation of free-surface turbulence using ultrasonic sensors}, series = {Flow Measurement and Instrumentation}, volume = {60}, journal = {Flow Measurement and Instrumentation}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0955-5986}, doi = {10.1016/j.flowmeasinst.2018.02.009}, pages = {171 -- 184}, year = {2018}, abstract = {Accurate determination of free-surface dynamics has attracted much research attention during the past decade and has important applications in many environmental and water related areas. In this study, the free-surface dynamics in several turbulent flows commonly found in nature were investigated using a synchronised setup consisting of an ultrasonic sensor and a high-speed video camera. Basic sensor capabilities were examined in dry conditions to allow for a better characterisation of the present sensor model. The ultrasonic sensor was found to adequately reproduce free-surface dynamics up to the second order, especially in two-dimensional scenarios with the most energetic modes in the low frequency range. The sensor frequency response was satisfactory in the sub-20 Hz band, and its signal quality may be further improved by low-pass filtering prior to digitisation. The application of the USS to characterise entrapped air in high-velocity flows is also discussed.}, language = {en} } @article{ZieburaBremenSchleifenbaumetal.2018, author = {Ziebura, Dawid and Bremen, Sebastian and Schleifenbaum, Johannes Henrich and Gebhardt, Andreas}, title = {Machbarkeitsstudie zur Verarbeitung von nicht rostendem Stahl 1.4404 unter Verwendung einer Diodenlaser-basierten LPBF-Maschine mit kartesischem Achssystem}, series = {RTejournal - Forum f{\"u}r Rapid Technologie}, volume = {15}, journal = {RTejournal - Forum f{\"u}r Rapid Technologie}, issn = {1614-0923}, year = {2018}, language = {de} } @misc{OPUS4-8741, title = {Dimensionen 2-2018: Magazin der FH Aachen University of Applied Sciences - Virtuelle Realit{\"a}ten}, address = {Aachen}, organization = {FH Aachen, University of Applied Sciences}, pages = {63 Seiten}, year = {2018}, abstract = {Virtuelle Realit{\"a}ten Inhaltsverzeichnis 6 Erweiterte Dimensionen: Special zum Thema Virtual Reality 10 "VR und AR werden unsere Welt durchdringen": Ein Interview zum Potenzial von Virtual und Augmented Reality 14 Lernen aus einem anderen Blickwinkel: VR wird in Studium und Lehre zunehmend angewandt 18 Parallele Realit{\"a}ten in der Forschung: Virtual und Augmented Reality in Forschungsprojekten 22 Willkommen in der Welt der M{\"o}glichkeiten: Wie real ist die Illusion der Realit{\"a}t 24 Eine z{\"u}ndende Idee: Institut f{\"u}r Mikrowellen- und Plasmatechnik (IMP) entwickelt neue Plasmaz{\"u}ndkerze f{\"u}r sparsamere Benzinmotoren 28 Der Elefant im Park: "WESTPARK story constructed": Studierende bauen skulpturales M{\"o}bel 30 Herr Bernoulli geht auf Reisen: Das "aero | race lab" bringt Experimente zur Luft- und Raumfahrt an die Schulen 32 Eine Auszeit vom Alltag: Martin Stockberg schafft Kunstwerke im Sand 36 Der Einer im urbanen Mobilit{\"a}tstetris: An der FH Aachen wird urbane Elektromobilit{\"a}t neu gedacht 39 Der Primzahlw{\"u}rfel: Kopfnuss 40 Schwarz Weiß Bunt: Die politische Kunst des FH-Absolventen Ralf Metzenmacher 44 Die Champions League des Schweißens: LaVa-X will das Laserstrahlschweißen im Vakuum etablieren 46 Auf der Suche nach dem goldenen Schnatz: St{\"o}cke statt Besen. Spielfeld statt Arena. In J{\"u}lich spielen Studierende Quidditch. 48 Bei ihm wird Science-Fiction zu Science-Fact: Volker Schmid erz{\"a}hlt von seiner Arbeit beim Deutschen Zentrum f{\"u}r Luft- und Raumfahrt (DLR) 52 Die Ideenschmieden: Junge Menschen aus aller Welt diskutieren bei den Summerschools {\"u}ber Zukunftsthemen 56 Forschung auf h{\"o}chstem Niveau: Dr. Jan Oberl{\"a}nder und Doktorand Dua {\"O}zsoylu stehen f{\"u}r das, was das Institut f{\"u}r Nano- und Biotechnologien auszeichnet 58 Der Dom und ich: Dompublikation und LEGO-Throne zum Jubil{\"a}um 40 Jahre UNESCO-Weltkulturerbe 62 Sag "Ja" zum Studium: Der neue kooperative Bachelorstudiengang "Elektrotechnik mit Orientierungssemester" 63 Impressum}, language = {de} } @misc{OPUS4-8740, title = {Dimensionen 1-2018: Magazin der FH Aachen University of Applied Sciences - Grenzg{\"a}nge}, organization = {FH Aachen, University of Applied Sciences}, pages = {62 Seiten}, year = {2018}, abstract = {Grenzg{\"a}nge: Op j{\"o}ck in Vaals mit Peter Sparla Inhaltsverzeichnis 6 "Mr. Vaals": Ein Spaziergang mit Peter Sparla durch die niederl{\"a}ndische Gemeinde 14 Ein Verein hebt ab: Von der Theorie in die Praxis: Die Flugtechnische Arbeitsgemeinschaft will Studierende f{\"u}rs Fliegen begeistern 18 Vom Flugplatzkind zur Ingenieurin: Sarah Hamacher hat Luft- und Raumfahrt studiert und arbeitet jetzt bei der ADAC-Luftfahrttechnik 20 Mit Sonne im Tank durch das australische Outback: FH-Student Enno D{\"u}lberg berichtet von der World Solar Challenge 24 Es steckt mehr dahinter: Eine Eschweiler Firma entwickelt Elektronik-L{\"o}sungen f{\"u}r Anh{\"a}ngerkupplungen - mit Unterst{\"u}tzung der FH Aachen 27 Von Mekn{\`e}s nach J{\"u}lich: Die Geschichte von Rabab Azizi 28 Das blaue Wunder neu erleben: Aachener Tuchtradition soll wieder in Mode kommen 32 Es werde Licht: Markus van Hauten macht spektakul{\"a}re Landschaftsfotos 36 Maschinenbau von morgen: Dr. Julia Kessler forscht zu additiv gefertigten Leichtbaustrukturen 39 Vier Siebenen und eine Eins: Kopfnuss 40 Auf Tuchf{\"u}hlung mit der Praxis: Das ausbildungsintegrierende Studium ist anspruchsvoll und fordernd. Aber es bietet den Studierenden und Unternehmen auch viel. 44 Eine große B{\"u}hne f{\"u}r die Forschung: FH aachen pr{\"a}sentiert das Spektrum ihrer wissenschaftlichen Arbeit 46 Eine Erfolgsstory: Das Institut f{\"u}r Nano- und Biotechnologien feiert sein 10-j{\"a}hriges Jubil{\"a}um 49 Das Ingenieurstudium fr{\"u}her und heute: Der Verein "Ingenieurfreunde der FH Aachen" blickt auf eine ereignisreiche Zeit zur{\"u}ck 50 Ist es ein Flugzeug? Ist es ein Multikopter: Nein es ist PhoenAix! Das Flugger{\"a}t soll Vorteile von Flugzeug- und Hubschraubertechnik kombinieren 54 G{\"u}terwagen der Zukunft: Im Studiengang Schienfahrzeugtechnik wird an intelligenten und hoch technisierten G{\"u}terwaggons gearbeitet 58 Wenn Gedanken Gestalt annehmen: Prof. Thomas T{\"u}nnemann zum Projekt Neo Forma 60 Vorhang auf f{\"u}r die Wissenschaft: Future-Lab-Gala im Theater Aachen 62 Impressum}, language = {de} }