@article{Heuermann2004, author = {Heuermann, Holger}, title = {A Synthesis Technique for Mono- and Mixed-Mode Symmetrical Filter}, series = {Conference proceedings : Tuesday 12th, Wednesday 13th and Thursday 14th October, [RAI International Exhibition and Congress Centre, Amsterdam ; part of European Microwave Week 2004] / EuMA, European Microwave Association . Vol. 1}, journal = {Conference proceedings : Tuesday 12th, Wednesday 13th and Thursday 14th October, [RAI International Exhibition and Congress Centre, Amsterdam ; part of European Microwave Week 2004] / EuMA, European Microwave Association . Vol. 1}, publisher = {Horizon House Publ}, address = {London}, isbn = {1-580-53992-0}, pages = {309 -- 312}, year = {2004}, language = {en} } @article{Heuermann1995, author = {Heuermann, Holger}, title = {LZY: A Self-Calibration Approach in Competition to the LRM Method for On-Wafer Measurements}, pages = {129 -- 136}, year = {1995}, language = {en} } @article{Heuermann2008, author = {Heuermann, Holger}, title = {Dual mode radio: A new tranceiver architecture for UWB and 60 GHz-applications}, series = {European Conference on Wireless Technology, 2008. EuWiT 2008.}, journal = {European Conference on Wireless Technology, 2008. EuWiT 2008.}, isbn = {978-2-87487-008-8}, pages = {147 -- 150}, year = {2008}, language = {en} } @article{Heuermann2008, author = {Heuermann, Holger}, title = {Calibration of a Network Analyzer Without a Thru Connection for Nonlinear and Multiport Measurements}, series = {IEEE Transactions on Microwave Theory and Techniques. 56 (2008), H. 11, 1}, journal = {IEEE Transactions on Microwave Theory and Techniques. 56 (2008), H. 11, 1}, isbn = {0018-9480}, pages = {2505 -- 2510}, year = {2008}, language = {en} } @article{Heuermann1999, author = {Heuermann, Holger}, title = {Calibration procedures with series impedances and unknown lines simplify on-wafer measurements}, series = {IEEE transactions on microwave theory and techniques : MTT ; a publication of the IEEE Microwave Theory and Techniques Society. 47 (1999), H. 1}, journal = {IEEE transactions on microwave theory and techniques : MTT ; a publication of the IEEE Microwave Theory and Techniques Society. 47 (1999), H. 1}, isbn = {0018-9480}, pages = {1 -- 5}, year = {1999}, language = {en} } @inproceedings{HessLuanSchwarteetal.2001, author = {Hess, Holger and Luan, Xuming and Schwarte, Rudolf and Zhang, Zhigang and Xu, Zhanping and Heinol, Horst-Guenther and Buxbaum, Bernd and Ringbeck, Thorsten}, title = {Three-dimensional intelligent sensing based on the PMD technology}, series = {Sensors, Systems, and Next-Generation Satellites V : 17 - 20 September 2001, Toulouse, France. - (SPIE proceedings series ; 4540)}, booktitle = {Sensors, Systems, and Next-Generation Satellites V : 17 - 20 September 2001, Toulouse, France. - (SPIE proceedings series ; 4540)}, editor = {Fujisada, Hiroyuki}, publisher = {SPIE}, address = {Bellingham, Wash.}, isbn = {0-8194-4265-8}, issn = {0038-7355}, pages = {482 -- 488}, year = {2001}, language = {en} } @inproceedings{HerzwurmPietsch2013, author = {Herzwurm, Georg and Pietsch, Wolfram}, title = {Introduction of RePriCo'13}, series = {19th International Working Conference on Requirements Engineering: Foundation for Software Quality (REFSQ 2013) : proceedings of the REFSQ 2013 Workshops CreaRE, IWSPM, and RePriCo, the REFSQ 2013 Empirical Track (Empirical Live Experiment and Empirical Research Fair), the REFSQ 2013 Doctoral Symposium, and the REFSQ 2013 Poster Session. ICB-research report. No. 56}, booktitle = {19th International Working Conference on Requirements Engineering: Foundation for Software Quality (REFSQ 2013) : proceedings of the REFSQ 2013 Workshops CreaRE, IWSPM, and RePriCo, the REFSQ 2013 Empirical Track (Empirical Live Experiment and Empirical Research Fair), the REFSQ 2013 Doctoral Symposium, and the REFSQ 2013 Poster Session. ICB-research report. No. 56}, publisher = {Duisburg-Essen}, address = {Univ.}, issn = {ISSN 1860-2770 (Print ) ; ISSN 1866-5101 (Online)}, pages = {103 -- 105}, year = {2013}, language = {en} } @inproceedings{HerzwurmPietsch2008, author = {Herzwurm, Georg and Pietsch, Wolfram}, title = {Guidelines for the analysis of IT business models and strategic positioning of IT-products}, series = {Second International Workshop on Software Product Management : IWSPM '08 : Barcelona, Catalunya, 09.09.2008}, booktitle = {Second International Workshop on Software Product Management : IWSPM '08 : Barcelona, Catalunya, 09.09.2008}, publisher = {IEEE}, address = {Piscataway, NJ}, organization = {Institute of Electrical and Electronics Engineers}, isbn = {978-1-4244-4083-2 (Print) ; 978-0-7695-3625-5 (E-Book)}, doi = {10.1109/IWSPM.2008.3}, pages = {1 -- 8}, year = {2008}, language = {en} } @article{HerzwurmKramsPietschetal.2012, author = {Herzwurm, Georg and Krams, Benedikt and Pietsch, Wolfram and Schockert, Sixten}, title = {Report from the 3rd international workshop on requirements prioritization for customer oriented software development (RePriCo'12)}, series = {ACM SIGSOFT Software Engineering Notes}, volume = {37}, journal = {ACM SIGSOFT Software Engineering Notes}, number = {4}, publisher = {Association for Computing Machinery}, address = {New York}, issn = {0163-5948}, doi = {10.1145/2237796.2237817}, pages = {32 -- 34}, year = {2012}, abstract = {Prioritization is an essential task within requirements engineering to cope with complexity and to establish focus properly. The 3rd Workshop on Requirements Prioritization for customer oriented Software Development (RePriCo'12) focused on requirements prioritization and adjacent themes in the context of customer oriented development of bespoke and standard software. Five submissions have been accepted for the proceedings and for presentation. The report summarizes and points out key findings.}, language = {en} } @article{HerzogPietrzykShahetal.2010, author = {Herzog, Hans and Pietrzyk, Uwe and Shah, N. Jon and Ziemons, Karl}, title = {The current state, challenges and perspectives of MR-PET}, series = {Neuroimage}, volume = {49}, journal = {Neuroimage}, number = {3}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1053-8119}, doi = {10.1016/j.neuroimage.2009.10.036}, pages = {2072 -- 2082}, year = {2010}, abstract = {Following the success of PET/CT during the last decade and the recent increasing proliferation of SPECT/CT, another hybrid imaging instrument has been gaining more and more interest: MR-PET. First combined, simultaneous PET and MR studies carried out in small animals demonstrated the feasibility of the new approach. Concurrently, some prototypes of an MR-PET scanner for simultaneous human brain studies have been built, their performance is being tested and preliminary applications have already been shown. Through this pioneering work, it has become clear that advances in the detector design are necessary for further optimization. Recently, the different issues related to the present state and future prospects of MR-PET were presented and discussed during an international 2-day workshop at the Forschungszentrum J{\"u}lich, Germany, held after, and in conjunction with, the 2008 IEEE Nuclear Science Symposium and Medical Imaging Conference in Dresden, Germany on October 27-28, 2008. The topics ranged from small animal MR-PET imaging to human MR-BrainPET imaging, new detector developments, challenges/opportunities for ultra-high field MR-PET imaging and considerations of possible future research and clinical applications. This report presents a critical summary of the contributions made to the workshop.}, language = {en} } @article{HerssensCowburnAlbrachtetal.2022, author = {Herssens, Nolan and Cowburn, James and Albracht, Kirsten and Braunstein, Bjoern and Cazzola, Dario and Colyer, Steffi and Minetti, Alberto E. and Pavei, Gaspare and Rittweger, J{\"o}rn and Weber, Tobias and Green, David A.}, title = {Movement in low gravity environments (MoLo) programme - the MoLo-L.O.O.P. study protocol}, series = {PLOS ONE / Public Library of Science}, volume = {17}, journal = {PLOS ONE / Public Library of Science}, number = {11}, editor = {Cattaneo, Luigi}, publisher = {Plos}, address = {San Francisco}, issn = {1932-6203}, doi = {10.1371/journal.pone.0278051}, pages = {e0278051}, year = {2022}, abstract = {Exposure to prolonged periods in microgravity is associated with deconditioning of the musculoskeletal system due to chronic changes in mechanical stimulation. Given astronauts will operate on the Lunar surface for extended periods of time, it is critical to quantify both external (e.g., ground reaction forces) and internal (e.g., joint reaction forces) loads of relevant movements performed during Lunar missions. Such knowledge is key to predict musculoskeletal deconditioning and determine appropriate exercise countermeasures associated with extended exposure to hypogravity.}, language = {en} } @inproceedings{HerrmannWorringerGraeteretal.2006, author = {Herrmann, Ulf and Worringer, S. and Graeter, F. and Nava, P.}, title = {Three Years of Operation Experience of the SKAL-ET Collector Loop at SEGS V}, series = {13th International Symposium Concentrated Solar Power and Chemical Energy Technologies, June 20 - 23, 2006, Seville, Spain}, booktitle = {13th International Symposium Concentrated Solar Power and Chemical Energy Technologies, June 20 - 23, 2006, Seville, Spain}, editor = {Romero, Manuel}, publisher = {SolarPACES [u.a.]}, address = {[s.l.]}, isbn = {84-7834-519-1}, pages = {1 CD-ROM}, year = {2006}, language = {en} } @inproceedings{HerrmannVorbruggNava2009, author = {Herrmann, Ulf and Vorbrugg, O. and Nava, P.}, title = {Construction and Commissioning Process of the Andasol Solar Field}, series = {SolarPACES 2009 : electricity, fuels and clean water powered by the sun ; 15 - 18 September 2009, Berlin, Germany ; the 15th SolarPACES conference ; proceedings}, booktitle = {SolarPACES 2009 : electricity, fuels and clean water powered by the sun ; 15 - 18 September 2009, Berlin, Germany ; the 15th SolarPACES conference ; proceedings}, publisher = {Deutsches Zentrum f{\"u}r Luft- u. Raumfahrt}, address = {Stuttgart}, isbn = {978-3-00-028755-8}, pages = {1 CD-ROM}, year = {2009}, language = {en} } @inproceedings{HerrmannRheinlaenderLippke1997, author = {Herrmann, Ulf and Rheinl{\"a}nder, J. and Lippke, F.}, title = {Solar Fields for Direct Steam Generation in Parabolic Trough Collectors}, series = {Components, tools, facilities and measurement techniques. - (Solar thermal concentrating technologies : proceedings of the 8th international symposium, October, 6 - 11, 1996, K{\"o}ln, Germany ; Vol. 2)}, booktitle = {Components, tools, facilities and measurement techniques. - (Solar thermal concentrating technologies : proceedings of the 8th international symposium, October, 6 - 11, 1996, K{\"o}ln, Germany ; Vol. 2)}, editor = {Becker, Manfred}, publisher = {M{\"u}ller}, address = {Heidelberg}, isbn = {3-7880-7616-X}, pages = {815 -- 834}, year = {1997}, language = {en} } @article{HerrmannLippke1999, author = {Herrmann, Ulf and Lippke, F.}, title = {The influence of transients on the design of DSG solar fields}, series = {Journal de Physique IV : proceedings}, volume = {9}, journal = {Journal de Physique IV : proceedings}, number = {PR3}, isbn = {2-86883-402-7}, issn = {1764-7177 (Online)}, doi = {10.1051/jp4:1999377}, pages = {489 -- 494}, year = {1999}, language = {en} } @article{HerrmannKellyPrice2002, author = {Herrmann, Ulf and Kelly, Bruce and Price, Henry}, title = {Two Tank Molten Salt Storage for Parabolic Trough Solar Power Plants}, series = {Energy : the international journal}, volume = {29}, journal = {Energy : the international journal}, number = {5-6 (Special Issue SolarPaces)}, issn = {0360-5442}, doi = {10.1016/S0360-5442(03)00193-2}, pages = {883 -- 893}, year = {2002}, language = {en} } @inproceedings{HerrmannKellyPrice2002, author = {Herrmann, Ulf and Kelly, Bruce and Price, Henry}, title = {Two Tank Molten Salt Storage for Parabolic Trough Solar Power Plants}, series = {Proceedings of the 11th SolarPACES International Symposium on Concentrated Solar Power and Chemical Energy Technologies : September 4 - 6, 2002, Zurich, Switzerland / Paul Scherrer Institut, PSI; ETH, Eidgen{\"o}ssische Technische Hochschule Z{\"u}rich}, booktitle = {Proceedings of the 11th SolarPACES International Symposium on Concentrated Solar Power and Chemical Energy Technologies : September 4 - 6, 2002, Zurich, Switzerland / Paul Scherrer Institut, PSI; ETH, Eidgen{\"o}ssische Technische Hochschule Z{\"u}rich}, editor = {Steinfeld, Aldo}, publisher = {Paul Scherrer Inst.}, address = {Villingen}, isbn = {3-9521409-3-7}, pages = {517 -- 524}, year = {2002}, language = {en} } @article{HerrmannKearney2002, author = {Herrmann, Ulf and Kearney, David W.}, title = {Survey of Thermal Energy Storage for Parabolic Trough Power Plants}, series = {Journal of Solar Energy Engineering}, volume = {124}, journal = {Journal of Solar Energy Engineering}, number = {2}, issn = {1528-8986 (Online)}, doi = {10.1115/1.1467601}, pages = {145 -- 152}, year = {2002}, language = {en} } @incollection{HerrmannKearneyRoegeretal.2017, author = {Herrmann, Ulf and Kearney, D. and R{\"o}ger, M. and Prahl, C.}, title = {System performance measurements}, series = {The Performance of Concentrated Solar Power (CSP) Systems : Modelling, Measurement and Assessment}, booktitle = {The Performance of Concentrated Solar Power (CSP) Systems : Modelling, Measurement and Assessment}, publisher = {Woodhead Publishing}, address = {Duxford}, isbn = {978-0-08-100448-7}, doi = {https://doi.org/10.1016/B978-0-08-100447-0.00005-5}, pages = {115 -- 165}, year = {2017}, abstract = {This chapter introduces performance and acceptance testing and describes state-of-the-art tools, methods, and instruments to assess the plant performance or realize plant acceptance testing. The status of the development of standards for performance assessment is given.}, language = {en} } @inproceedings{HerrmannGraeterNava2004, author = {Herrmann, Ulf and Graeter, F. and Nava, P.}, title = {Performance of the SKAL-ET Collector Loop at KJC Operating Company}, series = {12th International Symposium Solar Power and Chemical Energy Systems, October 6-8, 2004, Oaxaca Mexico ; SolarPACES International Symposium, 12}, booktitle = {12th International Symposium Solar Power and Chemical Energy Systems, October 6-8, 2004, Oaxaca Mexico ; SolarPACES International Symposium, 12}, editor = {Ramos, C.}, publisher = {Instituto de Investigaciones Electricas}, address = {[s.l.]}, isbn = {968-6114-18-1}, year = {2004}, language = {en} } @article{HeroldBrandtSeibleretal.2008, author = {Herold, Marco J. and Brandt, Jens van den and Seibler, Jost and Reichardt, Holger M.}, title = {Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats}, series = {Proceedings of the National Academy of Sciences of the United States of America}, volume = {105}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, number = {47}, issn = {1091-6490}, doi = {10.1073/pnas.0806213105}, pages = {18507 -- 18512}, year = {2008}, language = {en} } @inproceedings{HeringUlberTippkoetter2016, author = {Hering, T. and Ulber, Roland and Tippk{\"o}tter, Nils}, title = {Development of a screening system for antimicrobial surfaces}, series = {New frontiers of biotech-processes (Himmelfahrtstagung) : 02-04 May 2016, Rhein-Mosel-Halle, Koblenz/Germany}, booktitle = {New frontiers of biotech-processes (Himmelfahrtstagung) : 02-04 May 2016, Rhein-Mosel-Halle, Koblenz/Germany}, publisher = {DECHEMA}, address = {Frankfurt am Main}, pages = {129}, year = {2016}, language = {en} } @article{HerberErnstBussetal.1999, author = {Herber, R. and Ernst, S. and Buß, G. and Sch{\"o}ning, Michael Josef and Baltruschat, H.}, title = {Detection of hydrocarbons in air and water by adsorption on Pt electrodes using continuous impedance measurements}, series = {Proceedings of the Symposium on New Directions in Electroanalytical Chemistry II : [held at the 195th Meeting of the Electrochemical Society in Seattle, Washington on May 3 and 4, 1999] / Physical Electrochemistry, Sensor, and Organic and Biological Electrochemistry Divisions. Ed.: J. Leddy, P. Vanysek, M.D. Porter}, journal = {Proceedings of the Symposium on New Directions in Electroanalytical Chemistry II : [held at the 195th Meeting of the Electrochemical Society in Seattle, Washington on May 3 and 4, 1999] / Physical Electrochemistry, Sensor, and Organic and Biological Electrochemistry Divisions. Ed.: J. Leddy, P. Vanysek, M.D. Porter}, publisher = {Electrochemical Society}, address = {Pennington, NJ}, isbn = {1-56677-227-3}, pages = {168 -- 177}, year = {1999}, language = {en} } @article{HentschkeHagerHojdis2014, author = {Hentschke, Reinhard and Hager, Jonathan and Hojdis, Nils}, title = {Molecular Modeling Approach to the Prediction of Mechanical Properties of Silica-Reinforced Rubbers}, series = {Journal of Applied Polymer Science}, volume = {131}, journal = {Journal of Applied Polymer Science}, number = {18}, publisher = {Wiley}, address = {New York, NY}, issn = {1097-4628}, doi = {10.1002/app.40806}, pages = {1 -- 9}, year = {2014}, abstract = {Recently, we have suggested a nanomechanical model for dissipative loss in filled elastomer networks in the context of the Payne effect. The mechanism is based on a total interfiller particle force exhibiting an intermittent loop, due to the combination of short-range repulsion and dispersion forces with a long-range elastic attraction. The sum of these forces leads, under external strain, to a spontaneous instability of "bonds" between the aggregates in a filler network and attendant energy dissipation. Here, we use molecular dynamics simulations to obtain chemically realistic forces between surface modified silica particles. The latter are combined with the above model to estimate the loss modulus and the low strain storage modulus in elastomers containing the aforementioned filler-compatibilizer systems. The model is compared to experimental dynamic moduli of silica filled rubbers. We find good agreement between the model predictions and the experiments as function of the compatibilizer's molecular structure and its bulk concentration.}, language = {en} } @article{HenriquesJuradoGrieseretal.2020, author = {Henriques, A. and Jurado, B. and Grieser, M. and Denis-Petit, D. and Chiron, T. and Gaudefroy, L. and Glorius, J. and Langer, Christoph and Litvinov, Yu. A. and Mathieu, L. and Meot, V. and Perez-Sanchez, R. and Pibernat, J. and Reifarth, R. and Roig, O. and Thomas, B. and Thomas, B. A. and Thomas, J. C. and Tsekhanovich, I.}, title = {Indirect measurements of neutron cross-secti at heavy-ion storage rings}, series = {Journal of Physics: Conference Series}, volume = {1668}, journal = {Journal of Physics: Conference Series}, number = {Art. 012019}, publisher = {IOP}, address = {Bristol}, doi = {10.1088/1742-6596/1668/1/012019}, year = {2020}, abstract = {Cross sections for neutron-induced reactions of short-lived nuclei are essential for nuclear astrophysics since these reactions in the stars are responsible for the production of most heavy elements in the universe. These reactions are also key in applied domains like energy production and medicine. Nevertheless, neutron-induced cross-section measurements can be extremely challenging or even impossible to perform due to the radioactivity of the targets involved. Indirect measurements through the surrogate-reaction method can help to overcome these difficulties. The surrogate-reaction method relies on the use of an alternative reaction that will lead to the formation of the same excited nucleus as in the neutron-induced reaction of interest. The decay probabilities (for fission, neutron and gamma-ray emission) of the nucleus produced via the surrogate reaction allow one to constrain models and the prediction of the desired neutron cross sections. We propose to perform surrogate reaction measurements in inverse kinematics at heavy-ion storage rings, in particular at the CRYRING@ESR of the GSI/FAIR facility. We present the conceptual idea of the most promising setup to measure for the first time simultaneously the fission, neutron and gamma-ray emission probabilities. The results of the first simulations considering the 238U(d,d') reaction are shown, as well as new technical developments that are being carried out towards this set-up.}, language = {en} } @article{HennemannKohlReisertetal.2013, author = {Hennemann, J{\"o}rg and Kohl, Claus-Dieter and Reisert, Steffen and Kirchner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Copper oxide nanofibres for detection of hydrogen peroxide vapour at high concentrations}, series = {physica status solidi (a)}, volume = {210}, journal = {physica status solidi (a)}, number = {5}, publisher = {Wiley}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201200775}, pages = {859 -- 863}, year = {2013}, abstract = {We present a sensor concept based on copper(II)oxide (CuO) nanofibres for the detection of hydrogen peroxide (H2O2) vapour in the percent per volume (\% v/v) range. The fibres were produced by using the electrospinning technique. To avoid water condensation in the pores, the fibres were initially modified by an exposure to H2S to get an enclosed surface. By a thermal treatment at 350 °C the fibres were oxidised back to CuO. Thereby, the visible pores disappear which was verified by SEM analysis. The fibres show a decrease of resistance with increasing H2O2 concentration which is due to the fact that hydrogen peroxide is an oxidising gas and CuO a p-type semiconductor. The sensor shows a change of resistance within the minute range to the exposure until the maximum concentration of 6.9\% v/v H2O2. At operating temperatures below 450 °C the corresponding sensor response to a concentration of 4.1\% v/v increases. The sensor shows a good reproducibility of the signal at different measurements. CuO seems to be a suitable candidate for the detection of H2O2 vapour at high concentrations. Resistance behaviour of the sensor under exposure to H2O2 vapours between 2.3 and 6.9\% v/v at an operating temperature of 450 °C.}, language = {en} } @article{HenneckeSchwarzboezlHoffschmidtetal.2007, author = {Hennecke, Klaus and Schwarzb{\"o}zl, Peter and Hoffschmidt, Bernhard and G{\"o}ttsche, Joachim and Koll, G. and Beuter, M. and Hartz, T.}, title = {The solar power tower J{\"u}lich - a solar thermal power plant for test and demonstration of air receiver}, series = {Solar energy and human settlement : Elektronische Ressource : proceedings of ISES world congress 2007 ; (Vol. I - Vol. V) / [ISES Solar World Congress. ISES, International Solar Energy Society]. D. Yogi Goswami ; Yuwen Zhao}, journal = {Solar energy and human settlement : Elektronische Ressource : proceedings of ISES world congress 2007 ; (Vol. I - Vol. V) / [ISES Solar World Congress. ISES, International Solar Energy Society]. D. Yogi Goswami ; Yuwen Zhao}, publisher = {Tsinghua Univ. Press}, address = {Beijing}, isbn = {978-7-302-16146-2}, pages = {1749 -- 1753}, year = {2007}, language = {en} } @article{HenkenOosterhuisOehlschlaegeretal.2012, author = {Henken, F. E. and Oosterhuis, K. and {\"O}hlschl{\"a}ger, Peter and Bosch, L. and Hooijberg, E. and Haanen, J. B. A. G. and Steenbergen, R. D. M.}, title = {Preclinical safety evaluation of DNA vaccines encoding modified HPV16 E6 and E7}, series = {Vaccine}, volume = {30}, journal = {Vaccine}, number = {28}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0264-410X}, doi = {10.1016/j.vaccine.2012.04.013}, pages = {4259 -- 4266}, year = {2012}, abstract = {Persistent infection with high-risk human papillomaviruses (hrHPV) can result in the formation of anogenital cancers. As hrHPV proteins E6 and E7 are required for cancer initiation and maintenance, they are ideal targets for immunotherapeutic interventions. Previously, we have described the development of DNA vaccines for the induction of HPV16 E6 and E7 specific T cell immunity. These vaccines consist of 'gene-shuffled' (SH) versions of HPV16 E6 and E7 that were fused to Tetanus Toxin Fragment C domain 1 (TTFC) and were named TTFC-E6SH and TTFC-E7SH. Gene-shuffling was performed to avoid the risk of inducing malignant transformation at the vaccination site. Here, we describe the preclinical safety evaluation of these candidate vaccines by analysis of their transforming capacity in vitro using established murine fibroblasts (NIH 3T3 cells) and primary human foreskin keratinocytes (HFKs). We demonstrate that neither ectopic expression of TTFC-E6SH and TTFC-E7SH alone or in combination enabled NIH 3T3 cells to form colonies in soft agar. In contrast, expression of HPV16 E6WT and E7WT alone or in combination resulted in effective transformation. Similarly, retroviral transduction of HFKs from three independent donors with both TTFC-E6SH and TTFC-E7SH alone or in combination did not show any signs of immortalization. In contrast, the combined expression of E6WT and E7WT induced immortalization in HFKs from all donors. Based on these results we consider it justified to proceed to clinical evaluation of DNA vaccines encoding TTFC-E6SH and TTFC-E7SH in patients with HPV16 associated (pre)malignancies.}, language = {en} } @article{HengsbachEngelCwienczeketal.2023, author = {Hengsbach, Jan-Niklas and Engel, Mareike and Cwienczek, Marcel and Stiefelmaier, Judith and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {Scalable unseparated bioelectrochemical reactors by using a carbon fiber brush as stirrer and working electrode}, series = {ChemElectroChem}, volume = {10}, journal = {ChemElectroChem}, number = {21}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {2196-0216}, doi = {10.1002/celc.202300440}, pages = {9 Seiten}, year = {2023}, abstract = {The concept of energy conversion into platform chemicals using bioelectrochemical systems (BES) has gained increasing attention in recent years, as the technology simultaneously provides an opportunity for sustainable chemical production and tackles the challenge of Power-to-X technologies. There are many approaches to realize the industrial scale of BES. One concept is to equip standard bioreactors with static electrodes. However, large installations resulted in a negative influence on various reactor parameters. In this study, we present a new single-chamber BES based on a stirred tank reactor in which the stirrer was replaced by a carbon fiber brush, performing the functions of the working electrode and the stirrer. The reactor is characterized in abiotic studies and electro-fermentations with Clostridium acetobutylicum. Compared to standard reactors an increase in butanol production of 20.14±3.66 \% shows that the new BES can be efficiently used for bioelectrochemical processes.}, language = {en} } @incollection{HendersonWolfScheer2009, author = {Henderson, Colin J. and Wolf, C. Roland and Scheer, Nico}, title = {The use of transgenic animals to study drug metabolism}, series = {Handbook of Drug Metabolism. 2nd Edition}, booktitle = {Handbook of Drug Metabolism. 2nd Edition}, editor = {Woolf, Thomas F.}, publisher = {Informa Healthcare}, address = {New York}, isbn = {978-1-4200-7647-9}, pages = {637 -- 658}, year = {2009}, language = {en} } @article{HendersonScheerWolf2009, author = {Henderson, Colin J. and Scheer, Nico and Wolf, C. Roland}, title = {Advances in the generation of mouse models to elucidate the pathways of drug metabolism in rodents and man}, series = {Expert Review of Clinical Pharmacology}, volume = {2}, journal = {Expert Review of Clinical Pharmacology}, number = {2}, publisher = {Taylor \& Francis}, address = {London}, issn = {1751-2441}, doi = {10.1586/17512433.2.2.105}, pages = {105 -- 109}, year = {2009}, language = {en} } @article{HendersonMclaughlinScheeretal.2015, author = {Henderson, Colin J. and Mclaughlin, Lesley A. and Scheer, Nico and Stanley, Lesley A. and Wolf, C. Roland}, title = {Cytochrome b5 Is a Major Determinant of Human Cytochrome P450 CYP2D6 and CYP3A4 Activity In Vivo s}, series = {Molecular Pharmacology}, volume = {87}, journal = {Molecular Pharmacology}, number = {4}, publisher = {ASPET}, address = {Bethesda}, issn = {1521-0111}, doi = {10.1124/mol.114.097394}, pages = {733 -- 739}, year = {2015}, language = {en} } @article{HemmerlingMerschenzQuackWunderlich1988, author = {Hemmerling, H.-J. and Merschenz-Quack, Angelika and Wunderlich, H.}, title = {Crystal structures of indeno[1,2-d]imidazoles. XIth European Crystallographic Meeting, Vienna 1988}, series = {Zeitschrift f{\"u}r Kristallographie - Crystalline Materials}, volume = {185}, journal = {Zeitschrift f{\"u}r Kristallographie - Crystalline Materials}, number = {H. 1-4}, issn = {2196-7105 (E-Books); 2194-4946 (Print)}, pages = {256}, year = {1988}, language = {en} } @article{HelsperWiedensohlerWeiseetal.1986, author = {Helsper, Christoph and Wiedensohler, A. and Weise, W. and L{\"u}tkemeier, E.}, title = {Determination of the Bipolar Charge Equilibrium in Pure Gases / Wiedensohler, A. ; Weise, W. ; Helsper, C. ; L{\"u}tkemeier, E.}, series = {Aerosols : formation and reactivity ; proceedings of the second International Aerosol Conference, 22-26 Sept. 1986, Berlin (West) / Gesellschaft f{\"u}r Aerosolforschung (GAeF) ; American Association for Aerosol Research (AAAR)}, journal = {Aerosols : formation and reactivity ; proceedings of the second International Aerosol Conference, 22-26 Sept. 1986, Berlin (West) / Gesellschaft f{\"u}r Aerosolforschung (GAeF) ; American Association for Aerosol Research (AAAR)}, publisher = {Pergamon Press}, address = {Oxford [u.a.]}, pages = {383 -- 386}, year = {1986}, language = {en} } @article{HelsperWiedensohlerLuetkemeieretal.1986, author = {Helsper, Christoph and Wiedensohler, A. and L{\"u}tkemeier, E. and Feldpausch, M.}, title = {Investigation on the Bipolar Charge Distribution at Various Gas Conditions / Wiedensohler, A.; L{\"u}tkemeier, E.; Feldpausch, M. ; Helsper, C.}, series = {Journal of Aerosol Science. 17 (1986), H. 3}, journal = {Journal of Aerosol Science. 17 (1986), H. 3}, isbn = {0021-8502}, pages = {413 -- 416}, year = {1986}, language = {en} } @article{HelsperNiessnerRoenicke1984, author = {Helsper, Christoph and Nießner, R. and R{\"o}nicke, G.}, title = {Application of a Multistep Condensation Nuclei Counter as a Detector for Particle Surface Composition / Nießner, R.; Helsper, C.; R{\"o}nicke, G.}, series = {Aerosols : science, technology, and industr. applications of airborne particles ; proceedings of the 1. Internat. Aerosol Conference held Sept. 17-21, 1984, Minneapolis, Minn., U.S.A / ed.: Benjamin Y. H. Liu}, journal = {Aerosols : science, technology, and industr. applications of airborne particles ; proceedings of the 1. Internat. Aerosol Conference held Sept. 17-21, 1984, Minneapolis, Minn., U.S.A / ed.: Benjamin Y. H. Liu}, publisher = {Elsevier}, address = {New York [u.a.]}, isbn = {0444009477}, pages = {63 -- 66}, year = {1984}, language = {en} } @article{HelsperNiessner1985, author = {Helsper, Christoph and Nießner, R.}, title = {Application of a Multistep Condensation Nuclei Counter as a Detector for Particle Surface Composition / Nießner, R. ; Helsper, C.}, series = {Journal of Aerosol Science. 16 (1985), H. 3}, journal = {Journal of Aerosol Science. 16 (1985), H. 3}, isbn = {0021-8502}, pages = {201 -- 209}, year = {1985}, language = {en} } @article{HelsperNiessner1985, author = {Helsper, Christoph and Nießner, R.}, title = {On the Influence of the Vapour Substance on the Behaviour of an Expansion Type Condensation Nucleus Counter}, series = {Journal of Aerosol Science. 16 (1985), H. 5}, journal = {Journal of Aerosol Science. 16 (1985), H. 5}, isbn = {0021-8502}, pages = {457 -- 461}, year = {1985}, language = {en} } @article{HelsperMoelterWillemer1987, author = {Helsper, Christoph and M{\"o}lter, W. and Willemer, W.}, title = {Fast and Automated Testing of Filter Media / M{\"o}lter, W. ; Helsper, C. ; Willemer, W.}, series = {FILTECH Conference 1987 : Utrecht, Holland; September 23 - 25 1987 / org. by the Filtration Society , Vol. 1.}, journal = {FILTECH Conference 1987 : Utrecht, Holland; September 23 - 25 1987 / org. by the Filtration Society , Vol. 1.}, publisher = {Filtration Society}, address = {Loughborough}, pages = {106 -- 112}, year = {1987}, language = {en} } @article{HelsperMoelterLoeffleretal.1993, author = {Helsper, Christoph and M{\"o}lter, W. and L{\"o}ffler, F. and Wadenpohl, C.}, title = {Investigations on a New Aerosol Generator for the Production of Carbon Aggregate Particles / Helsper, C. ; M{\"o}lter, W. ; L{\"o}ffler, F. ; Wadenpohl, C. ; Kaufmann, S. ; Wenninger, G.}, series = {Atmospheric Environment. Part A. General Topics. 27 A (1993), H. 8}, journal = {Atmospheric Environment. Part A. General Topics. 27 A (1993), H. 8}, isbn = {1352-2310}, pages = {1271 -- 1275}, year = {1993}, language = {en} } @article{HelsperMoelterKaminski1989, author = {Helsper, Christoph and M{\"o}lter, W. and Kaminski, S.}, title = {Fast and Automated Testing of Different Air Filter Media / M{\"o}lter, W. ; Helsper, C. ; Kaminski, S.}, series = {1. Europ{\"a}isches Symposium Partikelabscheidung aus Gasen : [PARTEC, N{\"u}rnberg, West Germany, 19. - 21. April 1989 ; preprints] = 1. European Symposium Separation of Particles from Gases / [Organisation und Durchf{\"u}hrung: N{\"u}rnbergMesse]. Hrsg. von: Friedrich L{\"o}ffler}, journal = {1. Europ{\"a}isches Symposium Partikelabscheidung aus Gasen : [PARTEC, N{\"u}rnberg, West Germany, 19. - 21. April 1989 ; preprints] = 1. European Symposium Separation of Particles from Gases / [Organisation und Durchf{\"u}hrung: N{\"u}rnbergMesse]. Hrsg. von: Friedrich L{\"o}ffler}, publisher = {N{\"u}rnbergMesse}, address = {N{\"u}rnberg}, pages = {441 -- 457}, year = {1989}, language = {en} } @article{HelsperMoelterKaminski1989, author = {Helsper, Christoph and M{\"o}lter, W. and Kaminski, S.}, title = {Fast and Automated Testing of Different Air Filter Media / M{\"o}lter, W. ; Helsper, C. ; Kaminski, S.}, series = {Proceedings of the Filtech Conference, Karlsruhe 1989, Vol. 1}, journal = {Proceedings of the Filtech Conference, Karlsruhe 1989, Vol. 1}, publisher = {Filtration Society}, address = {Oadby}, pages = {125 -- 136}, year = {1989}, language = {en} } @article{HelsperMoelterKaminski1992, author = {Helsper, Christoph and M{\"o}lter, W. and Kaminski, S.}, title = {Fast, Automated Testing of Different Air Filter Media / M{\"o}lter, W. ; Helsper, C. ; Kaminski, S.}, series = {Filtration and Separation. 29 (1992), H. 1}, journal = {Filtration and Separation. 29 (1992), H. 1}, isbn = {0015-1882}, pages = {45 -- 50}, year = {1992}, language = {en} } @article{HelsperMoelterHaller1990, author = {Helsper, Christoph and M{\"o}lter, W. and Haller, P.}, title = {Representative Dilution of Aerosols by a Factor of 10,000}, series = {Journal of Aerosol Science. 21 (1990), H. Suppl. 1}, journal = {Journal of Aerosol Science. 21 (1990), H. Suppl. 1}, isbn = {0021-8502}, pages = {637 -- 640}, year = {1990}, language = {en} } @article{HelsperMoelter1991, author = {Helsper, Christoph and M{\"o}lter, W.}, title = {Characteristics of a Nebulizer with Cyclone Preseparator / M{\"o}lter, W. ; Helsper, C.}, series = {Aerosols, their generation, behaviour and applications. Annual Conference of the Aerosol Society / Aerosol Society (UK) ; 5.}, journal = {Aerosols, their generation, behaviour and applications. Annual Conference of the Aerosol Society / Aerosol Society (UK) ; 5.}, address = {Loughborough}, pages = {89 -- 94}, year = {1991}, language = {en} } @article{HelsperMoelter1989, author = {Helsper, Christoph and M{\"o}lter, L.}, title = {Erzeugung von Pr{\"u}faerosolen f{\"u}r die Kalibrierung von optischen Partikelmeßverfahren nach VDI 3491}, series = {Technisches Messen. 56 (1989)}, journal = {Technisches Messen. 56 (1989)}, isbn = {0171-8096}, pages = {229 -- 234}, year = {1989}, language = {en} } @article{HelsperLuetkemeierWiedensohler1986, author = {Helsper, Christoph and L{\"u}tkemeier, E. and Wiedensohler, A.}, title = {Charge Distribution by Unipolar Charging of Small Aerosol Particles / L{\"u}tkemeier, E. ; Helsper, C. ; Wiedensohler, A.}, series = {Aerosols : formation and reactivity ; proceedings of the second International Aerosol Conference, 22-26 Sept. 1986, Berlin (West) / Gesellschaft f{\"u}r Aerosolforschung (GAeF) ; American Association for Aerosol Research (AAAR)}, journal = {Aerosols : formation and reactivity ; proceedings of the second International Aerosol Conference, 22-26 Sept. 1986, Berlin (West) / Gesellschaft f{\"u}r Aerosolforschung (GAeF) ; American Association for Aerosol Research (AAAR)}, publisher = {Pergamon Press}, address = {Oxford [u.a.]}, pages = {474 -- 478}, year = {1986}, language = {en} } @article{HelsperHornSchneideretal.2008, author = {Helsper, Christoph and Horn, Hans-Georg and Schneider, Friedhelm and Wehner, Birgit}, title = {Intercomparison of five mobility size spectrometers for measuring atmospheric submicrometer aerosol particles / Helsper, Christoph ; Horn, Hans-Georg ; Schneider, Friedhelm ; Wehner, Birgit ; Wiedensohler, Alfred}, series = {Gefahrstoffe, Reinhaltung der Luft. Air Quality Control. 68 (2008), H. 11-12}, journal = {Gefahrstoffe, Reinhaltung der Luft. Air Quality Control. 68 (2008), H. 11-12}, isbn = {0949-8036}, pages = {475 -- 481}, year = {2008}, language = {en} } @article{HelsperFissanThielen1983, author = {Helsper, Christoph and Fißan, H. J. and Thielen, H. J.}, title = {Determination of Particle Size Distributions by Means of an Electrostatic Classifier / Fißan, H. J.; Helsper, C. ; Thielen, H. J.}, series = {Journal of Aerosol Science. 14 (1983), H. 3}, journal = {Journal of Aerosol Science. 14 (1983), H. 3}, isbn = {0021-8502}, pages = {354 -- 357}, year = {1983}, language = {en} } @article{HelsperFissanMugglietal.1983, author = {Helsper, Christoph and Fißan, H. J. and Muggli, J. and Scheidweiler, A.}, title = {Verification of Ionization Chamber Theory}, series = {Fire Technology. 19 (1983), H. 1}, journal = {Fire Technology. 19 (1983), H. 1}, isbn = {1572-8099}, pages = {14 -- 21}, year = {1983}, language = {en} } @article{HelsperFissanMugglietal.1980, author = {Helsper, Christoph and Fißan, H. J. and Muggli, J. and Scheidweiler, A.}, title = {Particle Number Distributions of Aerosols from Test Fires}, series = {Journal of Aerosol Science. 11 (1980), H. 5-6}, journal = {Journal of Aerosol Science. 11 (1980), H. 5-6}, isbn = {0021-8502}, pages = {439 -- 446}, year = {1980}, language = {en} } @article{HelsperFissanKasper1984, author = {Helsper, Christoph and Fißan, H. J. and Kasper, W.}, title = {Calibration of Optical Particle Counters with Respect to Particle Size / Fißan, H. J. ; Helsper, C.; Kasper, W.}, series = {Particle and Particle Systems Characterization. 1 (1984), H. 1984}, journal = {Particle and Particle Systems Characterization. 1 (1984), H. 1984}, isbn = {1521-4117}, pages = {108 -- 111}, year = {1984}, language = {en} } @article{HelsperFissanKapadietal.1982, author = {Helsper, Christoph and Fißan, H. J. and Kapadi, A. and Liu, B. Y. H.}, title = {Data Inversion by Simplex Minimization for the Electrical Aerosol Analyzer}, series = {Aerosol Science and Technology. 1 (1982), H. 1982}, journal = {Aerosol Science and Technology. 1 (1982), H. 1982}, isbn = {0278-6826}, pages = {136 -- 146}, year = {1982}, language = {en} } @article{HelsperFissan1983, author = {Helsper, Christoph and Fißan, H. J.}, title = {Calibration of the Polytec HC-15 and HC-70 Optical Particle Counters / Fißan, H. J. ; Helsper, C.}, series = {Aerosols in the mining and industrial work environments, Vol. 3. Instrumentation, Marple, Virgil A. ; Liu, Benjamin Y.}, journal = {Aerosols in the mining and industrial work environments, Vol. 3. Instrumentation, Marple, Virgil A. ; Liu, Benjamin Y.}, publisher = {Ann Arbor Science}, address = {Ann Arbor, Mich.}, pages = {825 -- 829}, year = {1983}, language = {en} } @article{HelsperFissan1979, author = {Helsper, Christoph and Fißan, H. J.}, title = {Numerical Simulation Studies and Data Reduction for Size Classifying Measurement Techniques / Fißan, H. J.; Helsper, C.}, series = {Aerosols in science, medicine and technology : conference / Gesellschaft f{\"u}r Aerosolforschung 7. 1979.}, journal = {Aerosols in science, medicine and technology : conference / Gesellschaft f{\"u}r Aerosolforschung 7. 1979.}, pages = {199 -- 205}, year = {1979}, language = {en} } @article{HelsperFissan1980, author = {Helsper, Christoph and Fißan, H. J.}, title = {Numerical Simulation Studies and Data Reduction for Size Classifying Measurement Techniques / Fißan, H. J.; Helsper, C.}, series = {Advances in Particle Sampling and Measurement: Proceedings, Daytona Beach, EPA 600/9 80 004, 1980}, journal = {Advances in Particle Sampling and Measurement: Proceedings, Daytona Beach, EPA 600/9 80 004, 1980}, publisher = {National Technical Information Service}, address = {Springfield, Va.}, pages = {VII, 409 S.}, year = {1980}, language = {en} } @article{HelsperFissan1981, author = {Helsper, Christoph and Fißan, H. J.}, title = {Response Characteristic of a Polytec HC-15 Optical Particle Counter}, series = {Aerosols in science, medicine and technology : Physical and chemical properties of aerosols : Association for Aerosol Research: annual conference. 1980 : Gesellschaft f{\"u}r Aerosolforschung: annual conference. 1980 : Aerosols in science, medicine and technology : Physical and chemical properties of aerosols : Associa-tion for Aerosol Research: annual conference. 1980 : Gesellschaft f{\"u}r Aerosolforschung: annual conference. 1980 : Schmallenberg, 22.10.80 - 24.10.80}, journal = {Aerosols in science, medicine and technology : Physical and chemical properties of aerosols : Association for Aerosol Research: annual conference. 1980 : Gesellschaft f{\"u}r Aerosolforschung: annual conference. 1980 : Aerosols in science, medicine and technology : Physical and chemical properties of aerosols : Associa-tion for Aerosol Research: annual conference. 1980 : Gesellschaft f{\"u}r Aerosolforschung: annual conference. 1980 : Schmallenberg, 22.10.80 - 24.10.80}, publisher = {Pergamon Pr.}, address = {Oxford}, pages = {287 -- 292}, year = {1981}, language = {en} } @incollection{HelsperFissanFranzen1978, author = {Helsper, Christoph and Fissan, H. J. and Franzen, H.}, title = {Particle Size Distributions of Combustion Aerosols}, series = {Atmospheric Pollution 1978 : Proceedings of the 13th International Colloquium; 25-28 April 1978; Paris, France; Edited by Michel M. Benarie}, booktitle = {Atmospheric Pollution 1978 : Proceedings of the 13th International Colloquium; 25-28 April 1978; Paris, France; Edited by Michel M. Benarie}, editor = {Benarie, Michel M.}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {0-444-41691-9}, doi = {10.1016/S0166-1116(08)71583-8}, pages = {263 -- 266}, year = {1978}, abstract = {It has been observed that carcinogenic polycyclic aromatic hydrocarbons (PAH) are present in the atmosphere. Combustion processes are considered the most important sources for PAH. Among these, the burning of coal produces the highest emission, but in cities with high traffic density and low meteorological exchange activities, vehicle emissions determine the immission situation, especially in narrow streets. For estimating the potential health effects caused by PAH, it is sufficient to characterize the emission of PAH with respect to their physical state, concentrations, and, as far as the particulate phase is concerned, size distribution. The size distribution is important for transport phenomena, inhalation, and deposition in the respiratory tract. These parameters mainly depend on the combustion system, on system operating conditions, on the exhaust system, and on exhaust cooling conditions. At exhaust-gas temperatures in the range of ambient air temperatures, almost the whole emission of PAH is made up of particulate matter.}, language = {en} } @article{HelsperDreilingHalleretal.1986, author = {Helsper, Christoph and Dreiling, V. and Haller, P. and Kaminski, U.}, title = {Intercomparison of Eleven Condensation Nucleus Counters / Dreiling, V. ; Haller, P. ; Helsper, C.; Kaminski, U. ; Plomp, A. ; Raes, F. ; Roth, C. ; Schier, J. ; Sch{\"u}rmann, G.}, series = {Journal of Aerosol Science. 17 (1986), H. 3}, journal = {Journal of Aerosol Science. 17 (1986), H. 3}, isbn = {0021-8502}, pages = {565 -- 570}, year = {1986}, language = {en} } @article{HelsperBartzFissanetal.1985, author = {Helsper, Christoph and Bartz, H. and Fißan, H. J. and Kousaka, Y. (u.a.)}, title = {Response Characteristics for Four Condensation Nucleus Counters to Particles in the 3 to 50 nm Diameter Range / Bartz, H. ; Fißan, H. J. ; Helsper, C.; Kousaka, Y. ; Okuyama, K. ; Keady, R. Fruin, S. ; McMurry, P. H.; Pui, D. Y. H. ; Stolzenburg, M. R.}, series = {Journal of Aerosol Science. 16 (1985), H. 5}, journal = {Journal of Aerosol Science. 16 (1985), H. 5}, isbn = {0021-8502}, pages = {443 -- 456}, year = {1985}, language = {en} } @article{Helsper1986, author = {Helsper, Christoph}, title = {Measurement Techniques For Ultrafine Particles}, series = {Ultrafine aerosols. Properties and behaviour. Proceedings of the 1. International Workshop on Ultrafine Aerosols of the Sonderforschungsbereich 209 'Stoff- und Energietransport in Aerosolen' -'Mass and energy transfer in aerosols'-, held at the Univ. of Duisburg on Sept. 29, 1986}, journal = {Ultrafine aerosols. Properties and behaviour. Proceedings of the 1. International Workshop on Ultrafine Aerosols of the Sonderforschungsbereich 209 'Stoff- und Energietransport in Aerosolen' -'Mass and energy transfer in aerosols'-, held at the Univ. of Duisburg on Sept. 29, 1986}, address = {Duisburg}, year = {1986}, language = {en} } @article{Helsper1979, author = {Helsper, Christoph}, title = {Evaluation of Particle Size Distributions by Means of Particle Counters / Fißan, H. J. ; Helsper, C.}, series = {Proceedings of the First Workshop of Particulate Control : 16. - 17. March 1978, Kernforschung-sanlage J{\"u}lich GmbH / prepared by U.S. Environmental Protection Agency, Off. of Research and Development, Washington, D.C, 1979,}, journal = {Proceedings of the First Workshop of Particulate Control : 16. - 17. March 1978, Kernforschung-sanlage J{\"u}lich GmbH / prepared by U.S. Environmental Protection Agency, Off. of Research and Development, Washington, D.C, 1979,}, publisher = {Zentralbibliothek d. Kernforschungsanlage J{\"u}lich [in Komm.]}, address = {J{\"u}lich}, pages = {495 S.: Ill., graph. Darst.}, year = {1979}, language = {en} } @incollection{HelmigBoonzaaijer2009, author = {Helmig, Ilka and Boonzaaijer, Karel}, title = {Growing 48 hours : design experiment in an aircraft hangar ...}, series = {Papercraft [1] : design and art with paper}, booktitle = {Papercraft [1] : design and art with paper}, publisher = {Gestalten Verlag}, address = {Berlin}, isbn = {978-3-89955-251-5}, pages = {224}, year = {2009}, subject = {Papierkunst}, language = {en} } @incollection{Helmig2011, author = {Helmig, Ilka}, title = {Friendship : editorial illustration}, series = {Papercraft 2 : design and art with paper}, booktitle = {Papercraft 2 : design and art with paper}, publisher = {Gestalten Verlag}, address = {Berlin}, isbn = {978-3-89955-333-8}, pages = {237}, year = {2011}, subject = {Papierkunst}, language = {en} } @article{Helmig2010, author = {Helmig, Ilka}, title = {Nitty - fontnames illustrated}, series = {Slanted}, journal = {Slanted}, number = {11}, publisher = {Slanted Publishers}, address = {Karlsruhe}, issn = {1867-6510}, pages = {68 -- 69}, year = {2010}, language = {en} } @article{Helmig2015, author = {Helmig, Ilka}, title = {A few (hi)stories about french illustration}, series = {Slanted}, journal = {Slanted}, number = {25 (Paris)}, publisher = {Slanted Publishers}, address = {Karlsruhe}, issn = {1867-6510}, pages = {210 -- 217}, year = {2015}, language = {en} } @incollection{Helmig2009, author = {Helmig, Ilka}, title = {Tristan und Isolde, Samson und Dalila, Capriccio : 3D illustration for posters of Cologne Opera}, series = {Papercraft [1] : design and art with paper}, booktitle = {Papercraft [1] : design and art with paper}, editor = {Klanten, Robert}, publisher = {Gestalten Verlag}, address = {Berlin}, isbn = {978-3-89955-251-5}, pages = {202}, year = {2009}, subject = {Papierkunst}, language = {en} } @article{HellwigVolkmann2005, author = {Hellwig, Angelika and Volkmann, Lutz}, title = {Neighborhood conditions for graphs and digraphs to be maximally edge-connected}, series = {Australasian journal of combinatorics}, volume = {Vol. 33}, journal = {Australasian journal of combinatorics}, issn = {10344942 ; 22023518}, pages = {265 -- 277}, year = {2005}, language = {en} } @article{HellwigVolkmann2005, author = {Hellwig, Angelika and Volkmann, Lutz}, title = {Sufficient conditions for graphs to be λ′-optimal, super-edge-connected, and maximally edge-connected}, series = {Journal of graph theory}, volume = {Vol. 48}, journal = {Journal of graph theory}, number = {Iss. 3}, issn = {03649024}, pages = {228 -- 246}, year = {2005}, language = {en} } @article{HellwigVolkmann2004, author = {Hellwig, Angelika and Volkmann, Lutz}, title = {Maximally local-edge-connected graphs and digraphs}, series = {Ars combinatoria}, volume = {Vol. 72}, journal = {Ars combinatoria}, issn = {0381-7032}, pages = {295 -- 306}, year = {2004}, language = {en} } @article{HellwigVolkmann2004, author = {Hellwig, Angelika and Volkmann, Lutz}, title = {Neighborhood and degree conditions for super-edge-connected bipartite digraphs}, series = {Results in mathematics}, volume = {Vol. 45}, journal = {Results in mathematics}, number = {Iss. 1-2}, issn = {1420-9012 (E-Journal); 1422-6383 (Print)}, pages = {45 -- 58}, year = {2004}, language = {en} } @article{HellwigVolkmann2004, author = {Hellwig, Angelika and Volkmann, Lutz}, title = {Sufficient conditions for λ′-optimality in graphs of diameter 2}, series = {Discrete mathematics}, volume = {Vol. 283}, journal = {Discrete mathematics}, number = {Iss. 1-3}, issn = {1872-681X (E-Journal); 0012-365X (Print)}, pages = {113 -- 120}, year = {2004}, language = {en} } @article{HellwigVolkmann2003, author = {Hellwig, Angelika and Volkmann, Lutz}, title = {Maximally edge-connected digraphs}, series = {Australasian journal of combinatorics}, volume = {Vol. 27}, journal = {Australasian journal of combinatorics}, issn = {1034-4942 (E-Journal); 1034-4942 (Print)}, pages = {23 -- 32}, year = {2003}, language = {en} } @article{HellwigVolkmann2008, author = {Hellwig, Angelika and Volkmann, Lutz}, title = {Maximally edge-connected and vertex-connected graphs and digraphs : a survey}, series = {Discrete mathematics}, volume = {Vol. 308}, journal = {Discrete mathematics}, number = {Iss. 15}, issn = {1872-681X (E-Journal); 0012-365X (Print)}, pages = {3265 -- 3296}, year = {2008}, language = {en} } @article{HellwigVolkmann2008, author = {Hellwig, Angelika and Volkmann, Lutz}, title = {The connectivity of a graph and its complement}, series = {Discrete applied mathematics}, volume = {Vol. 156}, journal = {Discrete applied mathematics}, number = {Iss. 17}, issn = {0166-218X (E-Journal); 1872-6771 (E-Journal); 0166-218X (Print)}, pages = {3325 -- 3328}, year = {2008}, language = {en} } @article{HellwigVolkmann2006, author = {Hellwig, Angelika and Volkmann, Lutz}, title = {Lower bounds on the vertex-connectivity of digraphs and graphs}, series = {Information processing letters}, volume = {Vol. 99}, journal = {Information processing letters}, number = {Iss. 2}, issn = {1872-6119 (E-Journal); 0020-0190 (Print)}, pages = {41 -- 46}, year = {2006}, language = {en} } @article{HellwigVolkmann2006, author = {Hellwig, Angelika and Volkmann, Lutz}, title = {On connectivity in graphs with given clique number}, series = {Journal of graph theory}, volume = {Vol. 52}, journal = {Journal of graph theory}, number = {Iss. 1}, issn = {03649024 ; 10970118}, pages = {7 -- 14}, year = {2006}, language = {en} } @article{HellwigVolkmann2006, author = {Hellwig, Angelika and Volkmann, Lutz}, title = {Some upper bounds for the domination number}, series = {The journal of combinatorial mathematics and combinatorial computing : JCMCC}, volume = {Vol. 57}, journal = {The journal of combinatorial mathematics and combinatorial computing : JCMCC}, issn = {0835-3026}, pages = {187 -- 209}, year = {2006}, language = {en} } @article{HellwigRautenbachVolkmann2004, author = {Hellwig, Angelika and Rautenbach, Dieter and Volkmann, Lutz}, title = {Note on the connectivity of line graphs}, series = {Information processing letters}, volume = {Vol. 91}, journal = {Information processing letters}, number = {Iss. 1}, issn = {1872-6119 (E-Journal); 0020-0190 (Print)}, pages = {7 -- 10}, year = {2004}, language = {en} } @article{HellwigRautenbachVolkmann2005, author = {Hellwig, Angelika and Rautenbach, Dieter and Volkmann, Lutz}, title = {Cuts leaving components of given minimum order}, series = {Discrete mathematics}, volume = {Vol. 292}, journal = {Discrete mathematics}, number = {Iss. 1-3}, issn = {1872-681X (E-Journal); 0012-365X (Print)}, pages = {55 -- 65}, year = {2005}, language = {en} } @inproceedings{HellmannsHartungDilgeretal.2009, author = {Hellmanns, Mark and Hartung, I. and Dilger, Klaus and B{\"o}hm, Stefan}, title = {Quality assurance of manual guided joining and welding devices}, series = {Proceedings of the IIW International Conference on Advances in Welding and Allied Technologies : July 16 - 17, 2009, Singapore}, booktitle = {Proceedings of the IIW International Conference on Advances in Welding and Allied Technologies : July 16 - 17, 2009, Singapore}, publisher = {International Institute of Welding}, address = {Roissy}, isbn = {9789810832605}, pages = {219 -- 222}, year = {2009}, language = {en} } @inproceedings{HellmannsBoehmDilger2008, author = {Hellmanns, Mark and B{\"o}hm, Stefan and Dilger, Klaus}, title = {Weight and noise reduction in power transmissions through epoxy resin foams}, series = {Proceedings of the 31st annual meeting of the Adhesion Society : 17. - 20.2.2008, Austin, Texas}, booktitle = {Proceedings of the 31st annual meeting of the Adhesion Society : 17. - 20.2.2008, Austin, Texas}, publisher = {Adhesion Society}, address = {Blacksburg}, organization = {Adhesion Society}, pages = {291 -- 293}, year = {2008}, language = {en} } @inproceedings{HellmannsBoehmDilger2006, author = {Hellmanns, Mark and B{\"o}hm, Stefan and Dilger, Klaus}, title = {Implementation of a velocity controlled manual applicator for adhesives and sealants in the automotive industry in consideration of quality control}, series = {Proceedings of the 29th annual meeting of the Adhesion Society : 19. - 22.2.2006, Jacksonville, Florida}, booktitle = {Proceedings of the 29th annual meeting of the Adhesion Society : 19. - 22.2.2006, Jacksonville, Florida}, publisher = {Adhesion Society}, address = {Blacksburg, Va.}, organization = {Adhesion Society}, issn = {1086-9506}, pages = {68 -- 70}, year = {2006}, language = {en} } @article{HellmannsBoehmDilger2006, author = {Hellmanns, Mark and B{\"o}hm, Stefan and Dilger, Klaus}, title = {Manual applications of adhesives}, series = {Journal of adhesion and interface}, volume = {Vol. 7}, journal = {Journal of adhesion and interface}, number = {No. 4}, pages = {24 -- 27}, year = {2006}, language = {en} } @inproceedings{HellmannsBoehmDilger2006, author = {Hellmanns, Mark and B{\"o}hm, Stefan and Dilger, Klaus}, title = {Progress of the manual application of adhesives}, series = {Proceedings of the 3rd World Congress on Adhesion and Related Phenomena : WCARP-III, October 15 -18, 2006, Beijing, China}, booktitle = {Proceedings of the 3rd World Congress on Adhesion and Related Phenomena : WCARP-III, October 15 -18, 2006, Beijing, China}, publisher = {Beijing Adhesion Society of China}, address = {Beijing}, pages = {275 -- 277}, year = {2006}, language = {en} } @article{HekmatSaleminkLauterbachetal.2004, author = {Hekmat, Khosro and Salemink, B. and Lauterbach, Gerhard and Schwinger, R. H. G. and S{\"u}dkamp, M. and Weber, Hans-Joachim and Mehlhorn, U.}, title = {Interference by cellular phones with permanent implanted pacemakers: an update}, series = {Europace. 6 (2004), H. 4}, journal = {Europace. 6 (2004), H. 4}, pages = {363 -- 369}, year = {2004}, language = {en} } @inproceedings{HeitzerStaat2000, author = {Heitzer, M. and Staat, Manfred}, title = {Direct FEM approach to design-by-analysis of pressurized components}, year = {2000}, abstract = {Abstracts of the ACHEMA 2000 - International Meeting on Chemical Engineering, Environmental Protection and Biotechnology, May 22 - 27, 2000. Frankfurt am Main. Achema 2000 : special edition / Linde. [Ed.: Linde AG. Red.: Volker R. Leski]. - Wiesbaden : Linde AG, 2000. - 56 p. : Ill., . - pp: 79 - 81}, subject = {Finite-Elemente-Methode}, language = {en} } @article{HeinzelSchaeferMuelleretal.2010, author = {Heinzel, Alexander and Sch{\"a}fer, Ralf and M{\"u}ller, Hans-Wilhelm and Schieffer, Andre and Ingenhag, Ariane and Northoff, Georg and Franz, Matthias and Hautzel, Hubertus}, title = {Differential modulation of valence and arousal in high-alexithymic and low-alexithymic individuals}, series = {Neuroreport}, volume = {21}, journal = {Neuroreport}, number = {15}, publisher = {Lippincott Williams \& Wilkins}, address = {London}, issn = {1473-558X}, doi = {10.1097/WNR.0b013e32833f38e0}, pages = {998 -- 1002}, year = {2010}, abstract = {High-alexithymic individuals are characterized by an impaired ability to identify and communicate emotions whereas low-alexithymic individuals have a wide-ranging ability to deal with emotions. This study examined the hypothesis that valence and arousal modifications of emotional stimuli differentially modulate cortical regions in high-alexithymic and low-alexithymic individuals. To this end, 28 high-alexithymic and 25 low-alexithymic individuals were investigated with event-related fMRI using visual emotional stimuli. We found differential neural activations in the dorsal anterior cingulate, the insula and the amygdala. We suggest that these differences may account for the impaired ability of high-alexithymic individuals to appropriately handle emotional stimuli.}, language = {en} } @article{HeinzelSchaeferMuelleretal.2010, author = {Heinzel, Alexander and Sch{\"a}fer, Ralf and M{\"u}ller, Hans-Wilhelm and Schieffer, Andre and Ingenhag, Ariane and Eickhoff, Simon B. and Northoff, Georg and Franz, Matthias and Hautzel, Hubertus}, title = {Increased Activation of the Supragenual Anterior Cingulate Cortex during Visual Emotional Processing in Male Subjects with High Degrees of Alexithymia: An Event-Related fMRI Study}, series = {Psychotherapy and Psychosomatics}, volume = {79}, journal = {Psychotherapy and Psychosomatics}, number = {6}, publisher = {Karger}, address = {Basel}, issn = {0033-3190}, doi = {10.1159/000320121}, pages = {363 -- 370}, year = {2010}, abstract = {Background: One of the most prominent neurobiological models of alexithymia assumes an altered function of the anterior cingulate cortex (ACC) as the crucial neural correlate of alexithymia. So far functional imaging studies have yielded inconclusive results. Therefore, we tested this hypothesis in healthy alexithymics and nonalexithymics in an event-related fMRI study. Methods: Thirty high- and 30 low-alexithymic right-handed male subjects (selected by the 20-item Toronto Alexithymia Scale, TAS-20) were investigated with event-related fMRI using a picture viewing paradigm. The stimuli consisted of happy, fearful and neutral facial expressions (Ekman-Friesen) as well as positive, negative and neutral pictures from the International Affective Picture System. Results: Contrasting the high-alexithymic with the low-alexithymic group we observed increased activation of the supragenual ACC for different emotional valences as well as for different emotional stimuli. Moreover, there was a positive correlation of the ACC with the individual TAS-20 scores but no correlations with the individual Beck Depression Inventory scores. Additionally, there was no difference in activity of the amygdala. Conclusions: We demonstrated that the supragenual ACC is constantly activated more strongly in alexithymic subjects and that this activation is related to the symptoms of alexithymia and not to associated symptoms such as depression. Therefore, our findings support the hypothesis of an altered function of the ACC in alexithymia.}, language = {en} } @article{HeinzeMangPeteretal.2014, author = {Heinze, Daniel and Mang, Thomas and Peter, Karin and M{\"o}ller, Martin and Weichold, Oliver}, title = {Synthesis of low molecular weight poly(vinyl acetate) and its application as plasticizer}, series = {Journal of applied polymer science}, volume = {131}, journal = {Journal of applied polymer science}, number = {9}, publisher = {Wiley}, address = {New York}, issn = {1097-4628 (E-Journal); 0021-8995 (Print)}, doi = {10.1002/app.40226}, pages = {Article No. 40226}, year = {2014}, abstract = {Poly(vinyl acetate), PVAc, with a degree of polymerization Xn = 10 was prepared by chain-transfer radical polymerization using carbon tetrachloride and used as oligomeric plasticizer for commercial PVAc. However, the chlorinated chain ends cause a low thermal stability requiring mild Cl/H substitution. The product exhibits high thermal stability and excellent melt-compounding properties. Blends of oligomeric and commercial PVAc show single glass transition temperatures which decrease with higher oligomer content and exhibit small negative deviations from Fox' linear additivity rule. This indicates plasticization and miscibility being mainly due to entropic effects. Injection-moulded thick specimens show ductile behaviour at oligomer contents >10 wt \%, while sheets with a thickness of 0.2-0.5 mm appear flexible already at 7.5 wt \%. The oxygen permeability coefficients are an order of magnitude lower than those of low-density polyethylene. Due to the sum of their properties, the plasticized sheets present a promising alternative in the preparation of barrier materials.}, language = {en} } @article{HeinzeMangPopescuetal.2016, author = {Heinze, D. and Mang, Thomas and Popescu, C. and Weichold, O.}, title = {Effect of side chain length and degree of polymerization on the decomposition and crystallization behaviour of chlorinated poly(vinyl ester) oligomers}, series = {Thermochimica Acta}, volume = {637}, journal = {Thermochimica Acta}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0040-6031 (electronic)}, doi = {10.1016/j.tca.2016.05.015}, pages = {143 -- 153}, year = {2016}, abstract = {Four members of a homologous series of chlorinated poly(vinyl ester) oligomers CCl₃-(CH₂CH (OCO(CH₂)ₘCH₃))ₙ-Cl with degrees of polymerization of 10 and 20 were prepared by telomerisation using carbon tetrachloride. The number of side chain carbon atoms ranges from 2 (poly(vinyl acetate) to 18 (poly(vinyl stearate)). The effect of the n-alkyl side chain length and of the degree of polymerization on the thermal stability and crystallization behaviour of the synthesized compounds was investigated. All oligomers degrade in two major steps by first losing HCl and side chains with subsequent breakdown of the backbone. The members with short side chains, up to poly(vinyl octanoate), are amorphous and show internal plasticization, whereas those with high number of side chain carbon atoms are semi-crystalline due to side-chain crystallization. A better packing for poly(vinyl stearate) is also noticeable. The glass transition and melting temperatures as well as the onset temperature of decomposition are influenced to a larger extent by the side chain length than by the degree of polymerization. Thermal stability is improved if both the size and number of side chains increase, but only a long side chain causes a significant increase of the resistance to degradation. This results in a stabilization of PVAc so that oligomers from poly(vinyl octanoate) on are stable under atmospheric conditions. Thus, the way to design stable, chlorinated PVEs oligomers is to use a long n-alkyl side chain.}, language = {en} } @inproceedings{HeinzOertelBung2010, author = {Heinz, G. and Oertel, Mario and Bung, Daniel Bernhard}, title = {Investigations on a cooling water system for a gas tubine facility concerning air vortexes and sediment transport}, series = {Hydraulic structures: useful water harvesting systems or relics? : Third International Junior Researcher and Engineer Workshop on Hydraulic Structures (IJREWHS'10) : Edinburgh, Scotland, U.K., 2-3 May 2010}, booktitle = {Hydraulic structures: useful water harvesting systems or relics? : Third International Junior Researcher and Engineer Workshop on Hydraulic Structures (IJREWHS'10) : Edinburgh, Scotland, U.K., 2-3 May 2010}, editor = {Janssen, Robert}, publisher = {School of Civil Engineering, The University of Queensland}, address = {Brisbane}, organization = {International Junior Researcher and Engineer Workshop on Hydraulic Structures <3, 2010, Edinburgh>}, isbn = {9781742720159}, pages = {109 -- 116}, year = {2010}, language = {en} } @article{HeinrichsUttingFrauenrathetal.2009, author = {Heinrichs, Uwe and Utting, Jane F. and Frauenrath, Tobias and Hezel, Fabian and Krombach, Gabriele A. and Hodenius, Michael A. J. and Kozerke, Sebastian and Niendorf, Thoralf}, title = {Myocardial T2 mapping free of distortion using susceptibility-weighted fast spin-echo imaging: A feasibility study at 1.5 T and 3.0 T}, series = {Magnetic Resonance in Medicine}, volume = {62}, journal = {Magnetic Resonance in Medicine}, number = {3}, publisher = {Wiley-Liss}, address = {New York}, issn = {1522-2594}, doi = {10.1002/mrm.22054}, pages = {822 -- 828}, year = {2009}, abstract = {This study demonstrates the feasibility of applying free-breathing, cardiac-gated, susceptibility-weighted fast spin-echo imaging together with black blood preparation and navigator-gated respiratory motion compensation for anatomically accurate T₂ mapping of the heart. First, T₂ maps are presented for oil phantoms without and with respiratory motion emulation (T₂ = (22.1 ± 1.7) ms at 1.5 T and T₂ = (22.65 ± 0.89) ms at 3.0 T). T₂ relaxometry of a ferrofluid revealed relaxivities of R2 = (477.9 ± 17) mM⁻¹s⁻¹ and R2 = (449.6 ± 13) mM⁻¹s⁻¹ for UFLARE and multiecho gradient-echo imaging at 1.5 T. For inferoseptal myocardial regions mean T₂ values of 29.9 ± 6.6 ms (1.5 T) and 22.3 ± 4.8 ms (3.0 T) were estimated. For posterior myocardial areas close to the vena cava T₂-values of 24.0 ± 6.4 ms (1.5 T) and 15.4 ± 1.8 ms (3.0 T) were observed. The merits and limitations of the proposed approach are discussed and its implications for cardiac and vascular T₂-mapping are considered.}, language = {en} } @article{HeinrichsPietrzykZiemons2003, author = {Heinrichs, U. and Pietrzyk, U. and Ziemons, Karl}, title = {Design optimization of the PMT-ClearPET prototypes based on simulation studies with GEANT3}, series = {2002 IEEE Nuclear Science Symposium Conference Record, Vol. 3}, journal = {2002 IEEE Nuclear Science Symposium Conference Record, Vol. 3}, issn = {1082-3654}, pages = {682 -- 686}, year = {2003}, abstract = {Within the Crystal Clear Collaboration four centres are developing 2nd generation high performance small animal PET scanners for different kinds of animals and medical applications. The first prototypes are PMT-based systems including depth of interaction (DOI) detection by using a phoswich layer of LSO and LuYAP. The aim of these simulation studies is to optimize sensitivity and spatial resolution of given designs, which vary in FOVs caused by different detector configurations (ring/octagon) and sizes. For this purpose the simulation tool GEANT3 (CERN) was used. The simulations have shown that all PMT designs with one-to-one coupling of crystals have a very nonlinear axial sensitivity profile. By shifting every other PMT 1/4 of a PMT length in axial direction the sampling of the FOVs became more homogeneous. At an energy threshold of 350keV the regression coefficient increases from 0.818 for the non-shifted to 0.993 for the shifted design. Simulations of a point source centred in the FOV (threshold: 350keV) resulted in sensitivities of 4.2\% for a 4×20PMT (LSO/LuYAP a 10mm) and 3.8\% for a 4×16PMT (LSO/LuYAP a 8mm) ring design. The 3D-MLEM reconstruction of a point source shows the enormous improvement of resolution using a crystal double layer with DOI (3.1mm at 40mm from CFOV) instead of a 20mm single layer (11.9mm).}, language = {en} } @article{HeinrichsPietrzykZiemons2003, author = {Heinrichs, U. and Pietrzyk, U. and Ziemons, Karl}, title = {Design optimization of the PMT-ClearPET prototypes based on simulation studies with GEANT3}, series = {IEEE Transactions on Nuclear Science}, volume = {50}, journal = {IEEE Transactions on Nuclear Science}, number = {5}, isbn = {0018-9499}, pages = {1428 -- 1432}, year = {2003}, abstract = {Within the Crystal Clear Collaboration (CCC), four centers are developing second generation high performance small animal positron emission tomography (PET) scanners for different kinds of animals and medical applications. The first prototypes are photomultiplier tube (PMT)-based systems including depth of interaction (DOI) detection by using a phoswich layer of lutetium oxyorthosilicate (LSO) and lutetium yttrium aluminum perovskite (LuYAP). The aim of these simulation studies is to optimize sensitivity and spatial resolution of given designs, which vary in fields of view (FOVs) caused by different detector configurations (ring/octagon) and sizes. For this purpose the simulation tool GEANT3 (CERN, Geneva, Switzerland) was used.}, language = {en} } @article{HeinrichsWeck1981, author = {Heinrichs, Horst and Weck, H.}, title = {Efficient finite-element structural analysis by interactive graphic mesh generation}, series = {CIRP Annals. 30 (1981), H. 1}, journal = {CIRP Annals. 30 (1981), H. 1}, pages = {279 -- 284}, year = {1981}, language = {en} } @article{HeinrichBlumBussmannetal.2002, author = {Heinrich, U. and Blum, A. and Bussmann, N. and Engels, R. and Kemmerling, G. and Weber, S. and Ziemons, Karl}, title = {Statistical studies on the light output and energy resolution of small LSO single crystals with different surface treatments combined with various reflector materials}, series = {Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment}, volume = {486}, journal = {Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment}, number = {1-2}, issn = {0168-9002}, pages = {60 -- 66}, year = {2002}, abstract = {The optimization of light output and energy resolution of scintillators is of special interest for the development of high resolution and high sensitivity PET. The aim of this work is to obtain statistically reliable results concerning optimal surface treatment of scintillation crystals and the selection of reflector material. For this purpose, raw, mechanically polished and etched LSO crystals (size 2×2×10 mm3) were combined with various reflector materials (Teflon tape, Teflon matrix, BaSO4) and exposed to a 22Na source. In order to ensure the statistical reliability of the results, groups of 10 LSO crystals each were measured for all combinations of surface treatment and reflector material. Using no reflector material the light output increased up to 551±35\% by mechanical polishing the surface compared to 100±5\% for raw crystals. Etching the surface increased the light output to 441±29\%. The untreated crystals had an energy resolution of 24.6±4.0\%. By mechanical polishing the surface it was possible to achieve an energy resolution of 13.2±0.8\%, by etching of 14.8±0.7\%. In combination with BaSO4 as reflector material the maximum increase of light output has been established to 932±57\% for mechanically polished and 895±61\% for etched crystals. The combination with BaSO4 also caused the best improvement of the energy resolution up to 11.6±0.2\% for mechanically polished and 12.2±0.3\% for etched crystals. Relating to the light output there was no significant statistical difference between the two surface treatments in combination with BaSO4. In contrast to this, the statistical results of the energy resolution have shown the combination of mechanical polishing and BaSO4 as the optimum.}, language = {en} } @article{HeinkeKnickerAlbracht2018, author = {Heinke, Lars N. and Knicker, Axel J. and Albracht, Kirsten}, title = {Evaluation of passively induced shoulder stretch reflex using an isokinetic dynamometer in male overhead athletes}, series = {Isokinetics and Exercise Science}, volume = {26}, journal = {Isokinetics and Exercise Science}, number = {4}, publisher = {IOS Press}, address = {Amsterdam}, issn = {1878-5913}, doi = {10.3233/IES-184111}, pages = {265 -- 274}, year = {2018}, abstract = {BACKGROUND: Muscle stretch reflexes are widely considered to beneficially influence joint stability and power generation in the lower limbs. While in the upper limbs and especially in the muscles surrounding the shoulder joint such evidence is lacking. OBJECTIVE: To quantify the electromyographical response in the muscles crossing the shoulder of specifically trained overhead athletes to an anterior perturbation force. METHODS: Twenty healthy male participants performed six sets of different external shoulder rotation stretches on an isokinetic dynamometer over a range of amplitudes and muscle pre-activation moment levels. All stretches were applied with a dynamometer acceleration of 10,000∘/s2 and a velocity of 150∘/s. Electromyographical response was measured via sEMG. RESULTS: Consistent reflexes were not observed in all experimental conditions. The reflex latencies revealed a significant muscle main effect (F (2,228) = 99.31, p< 0.001; η2= 0.466; f= 0.934) and a pre-activation main effect (F (1,228) = 142.21, p< 0.001; η2= 0.384; f= 1.418). The stretch reflex amplitude yielded a significant pre-activation main effect (F (1,222) = 470.373, p< 0.001; η2= 0.679; f= 1.454). CONCLUSION: Short latency muscle reflexes showed a tendency to an anterior to posterior muscle recruitment whereby the main internal rotator muscles of the shoulder revealed the most consistent results.}, language = {en} } @article{HeinkeKnickerAlbracht2020, author = {Heinke, Lars N. and Knicker, Axel J. and Albracht, Kirsten}, title = {Increased shoulder muscle stretch reflex elicitability in supine subject posture}, series = {Isokinetics and Exercise Science}, volume = {28}, journal = {Isokinetics and Exercise Science}, number = {2}, publisher = {IOS Press}, address = {Amsterdam}, issn = {1878-5913}, doi = {10.3233/IES-192219}, pages = {139 -- 146}, year = {2020}, abstract = {BACKGROUND: Muscle stretch reflexes are widely used to examine neural muscle function. The knowledge of reflex response in muscles crossing the shoulder is limited. OBJECTIVE: To quantify reflex modulation according to various subject postures and different procedures of muscle pre-activation steering. METHODS: Thirteen healthy male participants performed two sets of external shoulder rotation stretches in various positions and with different procedures of muscle pre-activation steering on an isokinetic dynamometer over a range of two different pre-activation levels. All stretches were applied with a dynamometer acceleration of 104∘/s2 and a velocity of 150∘/s. Electromyographical response was measured via sEMG. RESULTS: Consistent reflexive response was observed in all tested muscles in all experimental conditions. The reflex elicitation rate revealed a significant muscle main effect (F (5,288) = 2.358, ρ= 0.040; η2= 0.039; f= 0.637) and a significant test condition main effect (F (1,288) = 5.884, ρ= 0.016; η2= 0.020; f= 0.143). Reflex latency revealed a significant muscle pre-activation level main effect (F (1,274) = 5.008, ρ= 0.026; η2= 0.018; f= 0.469). CONCLUSION: Muscular reflexive response was more consistent in the primary internal rotators of the shoulder. Supine posture in combination with visual feedback of muscle pre-activation level enhanced the reflex elicitation rate.}, language = {en} } @article{HeinkeKnickerAlbracht2021, author = {Heinke, Lars N. and Knicker, Axel J. and Albracht, Kirsten}, title = {Test-retest reliability of the internal shoulder rotator muscles' stretch reflex in healthy men}, series = {Journal of Electromyography and Kinesiology}, volume = {62}, journal = {Journal of Electromyography and Kinesiology}, number = {Article 102611}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1050-6411}, doi = {10.1016/j.jelekin.2021.102611}, year = {2021}, abstract = {Until now the reproducibility of the short latency stretch reflex of the internal rotator muscles of the glenohumeral joint has not been identified. Twenty-three healthy male participants performed three sets of external shoulder rotation stretches with various pre-activation levels on two different dates of measurement to assess test-retest reliability. All stretches were applied with a dynamometer acceleration of 104°/s2 and a velocity of 150°/s. Electromyographical response was measured via surface EMG. Reflex latencies showed a pre-activation effect (ƞ2 = 0,355). ICC ranged from 0,735 to 0,909 indicating an overall "good" relative reliability. SRD 95\% lay between ±7,0 to ±12,3 ms.. The reflex gain showed overall poor test-retest reproducibility. The chosen methodological approach presented a suitable test protocol for shoulder muscles stretch reflex latency evaluation. A proof-of-concept study to validate the presented methodical approach in shoulder involvement including subjects with clinically relevant conditions is recommended.}, language = {en} }