@article{DiktaSubramanian2009, author = {Dikta, Gerhard and Subramanian, Sundarraman}, title = {Inverse censoring weighted median regression / Sundarraman Subramanian and Gerhard Dikta}, series = {Statistical Methodology. 6 (2009), H. 6}, journal = {Statistical Methodology. 6 (2009), H. 6}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {1572-3127}, pages = {594 -- 603}, year = {2009}, language = {en} } @article{DiktaReisselHarlass2016, author = {Dikta, Gerhard and Reißel, Martin and Harlaß, Carsten}, title = {Semi-parametric survival function estimators deduced from an identifying Volterra type integral equation}, series = {Journal of multivariate analysis}, journal = {Journal of multivariate analysis}, number = {147}, publisher = {Elsevier}, address = {Amsterdam}, doi = {10.1016/j.jmva.2016.02.008}, pages = {273 -- 284}, year = {2016}, abstract = {Based on an identifying Volterra type integral equation for randomly right censored observations from a lifetime distribution function F, we solve the corresponding estimating equation by an explicit and implicit Euler scheme. While the first approach results in some known estimators, the second one produces new semi-parametric and pre-smoothed Kaplan-Meier estimators which are real distribution functions rather than sub-distribution functions as the former ones are. This property of the new estimators is particular useful if one wants to estimate the expected lifetime restricted to the support of the observation time. Specifically, we focus on estimation under the semi-parametric random censorship model (SRCM), that is, a random censorship model where the conditional expectation of the censoring indicator given the observation belongs to a parametric family. We show that some estimated linear functionals which are based on the new semi-parametric estimator are strong consistent, asymptotically normal, and efficient under SRCM. In a small simulation study, the performance of the new estimator is illustrated under moderate sample sizes. Finally, we apply the new estimator to a well-known real dataset.}, language = {en} } @article{DiktaKuehlheimMendoncaetal.2015, author = {Dikta, Gerhard and K{\"u}hlheim, Ren{\´e} and Mendonca, Jorge and Una-Alcarez, Jacobo de}, title = {Asymptotic representation of presmoothed Kaplan-Meier integrals with covariates in a semiparametric censorship model}, series = {Journal of Statistical Planning and Inference}, volume = {Vol. 171}, journal = {Journal of Statistical Planning and Inference}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0378-3758}, doi = {10.1016/j.jspi.2015.12.001}, pages = {10 -- 37}, year = {2015}, language = {en} } @article{DiktaKvesicSchmidt2006, author = {Dikta, Gerhard and Kvesic, Marsel and Schmidt, Christian}, title = {Bootstrap Approximations in Model Checks for Binary Data}, series = {Journal of the American Statistical Association. 101 (2006), H. 474}, journal = {Journal of the American Statistical Association. 101 (2006), H. 474}, isbn = {0162-1459}, pages = {521 -- 530}, year = {2006}, language = {en} } @article{DiktaKurtzStute1989, author = {Dikta, Gerhard and Kurtz, B. and Stute, W.}, title = {Sequential Fixed-Width Confidence Bands for Distribution Functions Under Random Censoring}, series = {Metrika. 36 (1989)}, journal = {Metrika. 36 (1989)}, isbn = {0026-1335}, pages = {167 -- 176}, year = {1989}, language = {en} } @article{DiktaHausmannSchmidt2002, author = {Dikta, Gerhard and Hausmann, Rolf and Schmidt, Christian}, title = {Some Simulation Results under Random Censorship Models}, pages = {1 -- 12}, year = {2002}, language = {en} } @article{DiktaGhoraiSchmidt2005, author = {Dikta, Gerhard and Ghorai, Jugal and Schmidt, Christian}, title = {The Central Limit Theorem under Semiparametric Random Censorship Models}, series = {Journal of Statistical Planning and Inference. 127 (2005), H. 1}, journal = {Journal of Statistical Planning and Inference. 127 (2005), H. 1}, isbn = {0378-3758}, pages = {23 -- 51}, year = {2005}, language = {en} } @article{DiktaGhorai1990, author = {Dikta, Gerhard and Ghorai, J. K.}, title = {Bootstrap Approximation with Censored Data under the Proportional Hazard Model}, series = {Communications in Statistics: Theory and Methods. 19 (1990), H. 2}, journal = {Communications in Statistics: Theory and Methods. 19 (1990), H. 2}, isbn = {0361-0926}, pages = {573 -- 581}, year = {1990}, language = {en} } @article{DiktaDegenringFroemmeletal.2004, author = {Dikta, Gerhard and Degenring, D. and Froemmel, C. and Takors, R.}, title = {Sensitivity analysis for the reduction of complex metabolism models / Degenring, D. ; Froemmel, C. ; Dikta, G.; Takors, R.}, series = {Journal of Process Control. 14 (2004)}, journal = {Journal of Process Control. 14 (2004)}, isbn = {0959-1524}, pages = {729 -- 745}, year = {2004}, language = {en} } @article{Dikta2008, author = {Dikta, Gerhard}, title = {The Bootstrap in Binary Model Diagnostics}, series = {Frontiers of applied and computational mathematics : New Jersey Institute of Technology, USA, 19 - 21 May 2008 ; [dedicated to Daljit Singh Ahluwalia on his 75th birthday ; Fifth Annual Frontiers in Applied and Computational Mathematics Conference (FACM '08) ; selection of papers] / ed. by Denis Blackmore}, journal = {Frontiers of applied and computational mathematics : New Jersey Institute of Technology, USA, 19 - 21 May 2008 ; [dedicated to Daljit Singh Ahluwalia on his 75th birthday ; Fifth Annual Frontiers in Applied and Computational Mathematics Conference (FACM '08) ; selection of papers] / ed. by Denis Blackmore}, publisher = {World Scientific}, address = {Hackensack, NJ [u.a.]}, isbn = {978-981-283-528-4}, pages = {119 -- 126}, year = {2008}, language = {en} } @article{Dikta1993, author = {Dikta, Gerhard}, title = {A Note on the Rate of Convergence of the Bootstrap}, series = {Journal of Approximation Theory. 75 (1993), H. 1}, journal = {Journal of Approximation Theory. 75 (1993), H. 1}, isbn = {0021-9045}, pages = {112 -- 114}, year = {1993}, language = {en} } @article{Dikta1998, author = {Dikta, Gerhard}, title = {On Semiparametric Random Censorship Models}, series = {Journal of Statistical Planning and Inference. 66 (1998), H. 2}, journal = {Journal of Statistical Planning and Inference. 66 (1998), H. 2}, isbn = {0378-3758}, pages = {253 -- 279}, year = {1998}, language = {en} } @article{Dikta2000, author = {Dikta, Gerhard}, title = {The Strong Law under Semiparametric Random Censorship Models}, series = {Journal of Statistical Planning and Inference. 83 (2000), H. 1}, journal = {Journal of Statistical Planning and Inference. 83 (2000), H. 1}, isbn = {0378-3758}, pages = {1 -- 10}, year = {2000}, language = {en} } @article{Dikta2001, author = {Dikta, Gerhard}, title = {Weak Representation of the Cumulative Hazard Function under Semiparametric Random Censorship Models}, series = {Statistics. 35 (2001), H. 4}, journal = {Statistics. 35 (2001), H. 4}, isbn = {0233-1888}, pages = {395 -- 410}, year = {2001}, language = {en} } @article{Dikta2006, author = {Dikta, Gerhard}, title = {Time series methods to forecast patent filings}, series = {Forecasting innovations : methods for predicting numbers of patent filings ; with 71 tables / Peter Hingley ; Marc Nicolas (ed.),}, journal = {Forecasting innovations : methods for predicting numbers of patent filings ; with 71 tables / Peter Hingley ; Marc Nicolas (ed.),}, publisher = {Springer}, address = {Berlin [u.a.]}, isbn = {978-3-540-35991-3}, doi = {10.1007/3-540-35992-3_6}, pages = {95 -- 124}, year = {2006}, language = {en} } @article{Dikta1990, author = {Dikta, Gerhard}, title = {Bootstrap Approximation of Nearest Neighbor Regression Function Estimates}, series = {Journal of Multivariate Analysis. 32 (1990), H. 2}, journal = {Journal of Multivariate Analysis. 32 (1990), H. 2}, isbn = {0047-259X}, pages = {213 -- 229}, year = {1990}, language = {en} } @article{Dikta1995, author = {Dikta, Gerhard}, title = {Asymptotic Normality Under the Koziol-Green Model}, series = {Communications in Statistics: Theory and Methods. 24 (1995), H. 6}, journal = {Communications in Statistics: Theory and Methods. 24 (1995), H. 6}, isbn = {0361-0926}, pages = {1537 -- 1549}, year = {1995}, language = {en} } @article{Dikta2014, author = {Dikta, Gerhard}, title = {Asymptotically efficient estimation under semi-parametric random censorship models}, series = {Journal of multivariate analysis}, volume = {124}, journal = {Journal of multivariate analysis}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1095-7243 (E-Journal); 0047-259X (Print)}, doi = {10.1016/j.jmva.2013.10.002}, pages = {10 -- 24}, year = {2014}, abstract = {We study the estimation of some linear functionals which are based on an unknown lifetime distribution. The observations are assumed to be generated under the semi-parametric random censorship model (SRCM), that is, a random censorship model where the conditional expectation of the censoring indicator given the observation belongs to a parametric family. Under this setup a semi-parametric estimator of the survival function was introduced by the author. If the parametric model assumption is correct, it is known that the estimated functional which is based on this semi-parametric estimator is asymptotically at least as efficient as the corresponding one which rests on the nonparametric Kaplan-Meier estimator. In this paper we show that the estimated functional which is based on this semi-parametric estimator is asymptotically efficient with respect to the class of all regular estimators under this semi-parametric model.}, language = {en} } @article{Dikta2017, author = {Dikta, Gerhard}, title = {Semi-parametric random censorship models}, series = {From Statistics to Mathematical Finance : Festschrift in Honour of Winfried Stute}, journal = {From Statistics to Mathematical Finance : Festschrift in Honour of Winfried Stute}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-319-50986-0}, doi = {10.1007/978-3-319-50986-0_3}, pages = {43 -- 56}, year = {2017}, language = {en} } @article{DigelZhubanovaNojimaetal.2004, author = {Digel, Ilya and Zhubanova, Azhar A. and Nojima, H. and Artmann, Gerhard}, title = {The use of bactericidal effects of cluster ions generated by plasma in medical biotechnology}, series = {Biotechnologija : teorija i praktika (2004)}, journal = {Biotechnologija : teorija i praktika (2004)}, isbn = {1028-9399}, pages = {46 -- 52}, year = {2004}, language = {en} } @article{DigelZerlinTemizArtmannetal.2007, author = {Digel, Ilya and Zerlin, Kay and Temiz Artmann, Ayseg{\"u}l and Engels, S.}, title = {Protein dynamics in thermosensation}, series = {Regenerative medicine. 2 (2007), H. 5}, journal = {Regenerative medicine. 2 (2007), H. 5}, isbn = {1746-0751}, pages = {533 -- 533}, year = {2007}, language = {en} } @article{DigelWehlitzKayseretal.2018, author = {Digel, Ilya and Wehlitz, V. and Kayser, Peter and Figiel-Lange, A. and Bassam, R. and Rundstedt, F. von}, title = {Suspension depletion approach for exemption of infected Solanum jasminoides cells from pospiviroids}, series = {Plant Pathology}, volume = {67}, journal = {Plant Pathology}, number = {2}, publisher = {Wiley}, address = {Oxford}, issn = {1365-3059}, doi = {10.1111/ppa.12750}, pages = {358 -- 365}, year = {2018}, abstract = {Despite numerous studies, viroid elimination from infected plants remains a very challenging task. This study introduces for the first time a novel 'suspension depletion' approach for exemption of Solanum jasminoides plants from viroids. The proposed method implies initial establishment of suspension cultures of the infected plant cells. The suspended cells were then physically treated (mild thermotherapy, 33 °C), which presumably delayed the replication of the viroid. The viroid concentration in the treated biomass was monitored weekly using pospiviroid-specific PCR. After 10-12 weeks of continuous treatment, a sufficient decrease in viroid concentration was observed such that the infection became undetectable by PCR. The treated single cells then gave rise to microcolonies on a solid culture medium and the obtained viroid-negative clones were further promoted to regenerate into viroid-free plants. Three years of accumulated experimental data suggests feasibility, broad applicability, and good efficacy of the proposed approach.}, language = {en} } @article{DigelTrzewikDemircietal.2004, author = {Digel, Ilya and Trzewik, J{\"u}rgen and Demirci, Taylan and Temiz Artmann, Ayseg{\"u}l}, title = {Response of fibroblasts to cyclic mechanical stress : a proteome approach / Digel, I. ; Trzewik, J. ; Demirci, T. ; Temiz Artmann, A. ; Artmann, G. M.}, series = {Biomedizinische Technik. 49 (2004), H. Erg.-Bd. 2}, journal = {Biomedizinische Technik. 49 (2004), H. Erg.-Bd. 2}, isbn = {0932-4666}, pages = {1042 -- 1043}, year = {2004}, language = {en} } @article{DigelTemizArtmannNishikawaetal.2005, author = {Digel, Ilya and Temiz Artmann, Ayseg{\"u}l and Nishikawa, K. and Cook, M.}, title = {Bactericidal effects of plasma-generated cluster ions}, series = {Medical and Biological Engineering and Computing. 43 (2005), H. 6}, journal = {Medical and Biological Engineering and Computing. 43 (2005), H. 6}, isbn = {1741-0444}, pages = {800 -- 807}, year = {2005}, language = {en} } @article{DigelTemizArtmannNishikawaetal.2004, author = {Digel, Ilya and Temiz Artmann, Ayseg{\"u}l and Nishikawa, K. and Artmann, Gerhard}, title = {Cluster air-ion effects on bacteria and moulds}, series = {Biomedizinische Technik. 49 (2004), H. Erg.-Bd. 2}, journal = {Biomedizinische Technik. 49 (2004), H. Erg.-Bd. 2}, isbn = {0932-4666}, pages = {1040 -- 1041}, year = {2004}, language = {en} } @article{DigelTemizArtmann2011, author = {Digel, Ilya and Temiz Artmann, Ayseg{\"u}l}, title = {The emperor's new body : seeking for a blueprint of limb regeneration in humans}, series = {Stem cell engineering : principles and applications / Gerhard M. Artmann ... eds.}, journal = {Stem cell engineering : principles and applications / Gerhard M. Artmann ... eds.}, publisher = {Springer}, address = {Berlin [u.a.]}, isbn = {978-3-642-11864-7}, pages = {3 -- 37}, year = {2011}, language = {en} } @article{DigelMaggakisKelemenZerlinetal.2006, author = {Digel, Ilya and Maggakis-Kelemen, Christina and Zerlin, Kay and Linder, Peter}, title = {Body temperature-related structural transitions of monotremal and human hemoglobin}, series = {Biophysical Journal. 91 (2006), H. 8}, journal = {Biophysical Journal. 91 (2006), H. 8}, isbn = {1542-0086}, pages = {3014 -- 3021}, year = {2006}, language = {en} } @article{DigelKurulganDemirciLinderetal.2007, author = {Digel, Ilya and Kurulgan Demirci, Eylem and Linder, Peter and Kayser, Peter}, title = {Decrease in extracellular collagen crosslinking after NMR magnetic field application in skin fibroblasts}, series = {Medical and Biological Engineering and Computing. 45 (2007), H. 1}, journal = {Medical and Biological Engineering and Computing. 45 (2007), H. 1}, isbn = {1741-0444}, pages = {91 -- 97}, year = {2007}, language = {en} } @article{DigelKernGeenenetal.2020, author = {Digel, Ilya and Kern, Inna and Geenen, Eva-Maria and Akimbekov, Nuraly S.}, title = {Dental plaque removal by ultrasonic toothbrushes}, series = {dentistry journal}, volume = {8}, journal = {dentistry journal}, number = {28}, publisher = {MDPI}, address = {Basel}, issn = {2304-6767}, doi = {10.3390/dj8010028}, pages = {1 -- 13}, year = {2020}, abstract = {With the variety of toothbrushes on the market, the question arises, which toothbrush is best suited to maintain oral health? This thematic review focuses first on plaque formation mechanisms and then on the plaque removal effectiveness of ultrasonic toothbrushes and their potential in preventing oral diseases like periodontitis, gingivitis, and caries. We overviewed the physical effects that occurred during brushing and tried to address the question of whether ultrasonic toothbrushes effectively reduced the microbial burden by increasing the hydrodynamic forces. The results of published studies show that electric toothbrushes, which combine ultrasonic and sonic (or acoustic and mechanic) actions, may have the most promising effect on good oral health. Existing ultrasonic/sonic toothbrush models do not significantly differ regarding the removal of dental biofilm and the reduction of gingival inflammation compared with other electrically powered toothbrushes, whereas the manual toothbrushes show a lower effectiveness.}, language = {en} } @article{DigelKayserArtmann2008, author = {Digel, Ilya and Kayser, Peter and Artmann, Gerhard}, title = {Molecular processes in biological thermosensation}, series = {Journal of Biophysics. 2008 (2008)}, journal = {Journal of Biophysics. 2008 (2008)}, isbn = {1687-8000}, pages = {1 -- 9}, year = {2008}, language = {en} } @article{DigelDemirciTemizArtmannetal.2004, author = {Digel, Ilya and Demirci, Taylan and Temiz Artmann, Ayseg{\"u}l and Nishikawa, K.}, title = {Free Radical Nature of the Bactericidal Effect of Plasma-Generated Cluster Ions (PCIs)}, series = {Biomedizinische Technik. 49 (2004), H. Erg.-Bd. 2}, journal = {Biomedizinische Technik. 49 (2004), H. Erg.-Bd. 2}, isbn = {0932-4666}, pages = {982 -- 983}, year = {2004}, language = {en} } @article{DigelDachwaldArtmannetal.2009, author = {Digel, Ilya and Dachwald, Bernd and Artmann, Gerhard and Linder, Peter and Funke, O.}, title = {A concept of a probe for particle analysis and life detection in icy environments}, pages = {1 -- 24}, year = {2009}, language = {en} } @article{DigelAkimbekovTuralievaetal.2013, author = {Digel, Ilya and Akimbekov, Nuraly S. and Turalieva, M. and Mansurov, Z. and Temiz Artmann, Ayseg{\"u}l and Eshibaev, A. and Zhubanova, A.}, title = {Usage of Carbonized Plant Wastes for Purification of Aqueous Solutions}, series = {Journal of Industrial Technology and Engineering}, volume = {2}, journal = {Journal of Industrial Technology and Engineering}, number = {07}, pages = {47 -- 54}, year = {2013}, language = {en} } @article{DigelAkimbekovRogachevetal.2023, author = {Digel, Ilya and Akimbekov, Nuraly S. and Rogachev, Evgeniy and Pogorelova, Natalia}, title = {Bacterial cellulose produced by Medusomyces gisevii on glucose and sucrose: biosynthesis and structural properties}, series = {Cellulose}, journal = {Cellulose}, publisher = {Springer Science + Business Media}, address = {Dordrecht}, issn = {1572-882X (Online)}, doi = {10.1007/s10570-023-05592-z}, pages = {15 Seiten}, year = {2023}, abstract = {In this work, the effects of carbon sources and culture media on the production and structural properties of bacterial cellulose (BC) synthesized by Medusomyces gisevii have been studied. The culture medium was composed of different initial concentrations of glucose or sucrose dissolved in 0.4\% extract of plain green tea. Parameters of the culture media (titratable acidity, substrate conversion degree etc.) were monitored daily for 20 days of cultivation. The BC pellicles produced on different carbon sources were characterized in terms of biomass yield, crystallinity and morphology by field emission scanning electron microscopy (FE-SEM), atomic force microscopy and X-ray diffraction. Our results showed that Medusomyces gisevii had higher BC yields in media with sugar concentrations close to 10 g L-1 after a 18-20 days incubation period. Glucose in general lead to a higher BC yield (173 g L-1) compared to sucrose (163.5 g L-1). The BC crystallinity degree and surface roughness were higher in the samples synthetized from sucrose. Obtained FE-SEM micrographs show that the BC pellicles synthesized in the sucrose media contained densely packed tangles of cellulose fibrils whereas the BC produced in the glucose media displayed rather linear geometry of the BC fibrils without noticeable aggregates.}, language = {en} } @article{Digel2011, author = {Digel, Ilya}, title = {Primary thermosensory events in cells}, series = {Transient receptor potential channels / Md. Shahidul Islam, ed.}, journal = {Transient receptor potential channels / Md. Shahidul Islam, ed.}, publisher = {Springer}, address = {Dordrecht [u.a.]}, isbn = {978-94-007-0264-6}, pages = {451 -- 468}, year = {2011}, language = {en} } @article{Digel2008, author = {Digel, Ilya}, title = {Controlling microbial adhesion : a surface engineering approach}, series = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)}, journal = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)}, publisher = {Springer}, address = {Berlin [u.a.]}, isbn = {978-3-540-75408-4}, pages = {601 -- 625}, year = {2008}, language = {en} } @article{Digel2010, author = {Digel, Ilya}, title = {In-situ biological decontamination of an ice melting probe}, year = {2010}, language = {en} } @article{DietzelWeberPorschenetal.1976, author = {Dietzel, F. and Weber, Hans-Joachim and Porschen, W. and Feinendegen, L. E.}, title = {Zur W{\"a}rmeempfindlichkeit von oxischen und hypoxischen Zellen in einem Tumor}, series = {Naturwissenschaften}, volume = {63}, journal = {Naturwissenschaften}, number = {12}, publisher = {Springer}, address = {Heidelberg}, issn = {0028-1042}, doi = {10.1007/BF00622808}, pages = {585 -- 586}, year = {1976}, language = {de} } @article{DieringerRenzLindeletal.2011, author = {Dieringer, Matthias A. and Renz, Wolfgang and Lindel, Tomasz D. and Seifert, Frank and Frauenrath, Tobias and von Knobelsdorf-Brenkenhoff, Florian and Waiczies, Helmar and Hoffmann, Werner and Rieger, Jan and Pfeiffer, Harald and Ittermann, Bernd and Schulz-Menger, Jeanette and Niendorf, Thoralf}, title = {Design and application of a four-channel transmit/receive surface coil for functional cardiac imaging at 7T}, series = {Journal of Magnetic Resonance Imaging}, volume = {33}, journal = {Journal of Magnetic Resonance Imaging}, number = {3}, publisher = {Wiley-Liss}, address = {New York}, issn = {1522-2586}, doi = {10.1002/jmri.22451}, pages = {736 -- 741}, year = {2011}, abstract = {Purpose To design and evaluate a four-channel cardiac transceiver coil array for functional cardiac imaging at 7T. Materials and Methods A four-element cardiac transceiver surface coil array was developed with two rectangular loops mounted on an anterior former and two rectangular loops on a posterior former. specific absorption rate (SAR) simulations were performed and a Burn:x-wiley:10531807:media:JMRI22451:tex2gif-stack-1 calibration method was applied prior to obtain 2D FLASH CINE (mSENSE, R = 2) images from nine healthy volunteers with a spatial resolution of up to 1 × 1 × 2.5 mm3. Results Tuning and matching was found to be better than 10 dB for all subjects. The decoupling (S21) was measured to be >18 dB between neighboring loops, >20 dB for opposite loops, and >30 dB for other loop combinations. SAR values were well within the limits provided by the IEC. Imaging provided clinically acceptable signal homogeneity with an excellent blood-myocardium contrast applying the Burn:x-wiley:10531807:media:JMRI22451:tex2gif-stack-2 calibration approach. Conclusion A four-channel cardiac transceiver coil array for 7T was built, allowing for cardiac imaging with clinically acceptable signal homogeneity and an excellent blood-myocardium contrast. Minor anatomic structures, such as pericardium, mitral, and tricuspid valves and their apparatus, as well as trabeculae, were accurately delineated.}, language = {en} } @article{DienstOtt1972, author = {Dienst, Karl-Jakob and Ott, Udo}, title = {Spezielle nichtkommutative pappussche affine zweiseitige Inzidenzgruppen}, series = {Archiv der Mathematik}, volume = {23}, journal = {Archiv der Mathematik}, number = {1}, publisher = {Springer}, address = {Heidelberg}, isbn = {0003-889X}, doi = {10.1007/BF01304890}, pages = {329 -- 336}, year = {1972}, language = {de} } @article{Dienst1971, author = {Dienst, Karl-Jakob}, title = {Bewegungsgruppen projektiv-metrischer Ebenen von Char. 2}, series = {Journal f{\"u}r die reine und angewandte Mathematik}, volume = {250}, journal = {Journal f{\"u}r die reine und angewandte Mathematik}, publisher = {De Gruyter}, address = {Berlin}, isbn = {0075-4102}, doi = {10.1515/crll.1971.250.130}, pages = {130 -- 140}, year = {1971}, language = {de} } @article{Dienst1977, author = {Dienst, Karl-Jakob}, title = {Schnitt- und Zykelgeometrien}, series = {Geometriae Dedicata (1977)}, journal = {Geometriae Dedicata (1977)}, pages = {23 -- 54}, year = {1977}, language = {de} } @article{DielmannSchieke2000, author = {Dielmann, Klaus-Peter and Schieke, W.}, title = {Mikro-Gasturbinen : Aufbau und Anwendung}, series = {Gasturbinen f{\"u}r kombinierte Gas-Dampfturbinenanlagen : und Workshop Advanced Power Plant Processes for Solid Fuels Focussing on Combined Cycles ; Tagung Essen, 13. und 14. September 2000 / VDI-Gesellschaft Energietechnik. - (VDI-Berichte ; 1566)}, journal = {Gasturbinen f{\"u}r kombinierte Gas-Dampfturbinenanlagen : und Workshop Advanced Power Plant Processes for Solid Fuels Focussing on Combined Cycles ; Tagung Essen, 13. und 14. September 2000 / VDI-Gesellschaft Energietechnik. - (VDI-Berichte ; 1566)}, publisher = {VDI-Verl.}, address = {D{\"u}sseldorf}, isbn = {3-18-091566-8}, pages = {187 -- 210}, year = {2000}, language = {de} } @article{DielmannMehlkopfCudina2004, author = {Dielmann, Klaus-Peter and Mehlkopf, Marcus and Cudina, Boris}, title = {Erfahrungen mit der Software Risa-Gen}, series = {BWK : das Energie-Fachmagazin}, volume = {56}, journal = {BWK : das Energie-Fachmagazin}, number = {3}, isbn = {0006-9612}, issn = {1618-193X}, pages = {24 -- 25}, year = {2004}, language = {de} } @article{DielmannMehlkopfCudina2005, author = {Dielmann, Klaus-Peter and Mehlkopf, Marcus and Cudina, Boris}, title = {Der Handel mit Emissionsrechten : Vorbereitung auf den europaweiten Start 2005}, series = {VGB PowerTech : international journal for electricity and heat generation}, volume = {85}, journal = {VGB PowerTech : international journal for electricity and heat generation}, number = {1/2}, isbn = {1435-3199}, pages = {66 -- 69}, year = {2005}, language = {de} } @article{DielmannMehlkopf2005, author = {Dielmann, Klaus-Peter and Mehlkopf, Marcus}, title = {National zugeteilte Emissionen}, series = {BWK : das Energie-Fachmagazin}, volume = {57}, journal = {BWK : das Energie-Fachmagazin}, number = {5}, isbn = {0006-9612}, issn = {1618-193X}, pages = {48 -- 52}, year = {2005}, language = {de} } @article{DielmannKramer1982, author = {Dielmann, Klaus-Peter and Kramer, C.}, title = {Heißgasventilatoren f{\"u}r den Industrieofenbau / C. Kramer ; K.-P. Dielmann}, series = {Gasw{\"a}rme international : Gasanwendung in Industrie und Gewerbe. 31 (1982), H. 10}, journal = {Gasw{\"a}rme international : Gasanwendung in Industrie und Gewerbe. 31 (1982), H. 10}, isbn = {0020-9384}, pages = {461 -- 467}, year = {1982}, language = {de} } @article{DielmannIhle2000, author = {Dielmann, Klaus-Peter and Ihle, R.}, title = {Mikroturbinen : neue Chancen der Kraft-W{\"a}rme-(K{\"a}lte-)Kopplung im Leistungsbereich 30 - 200 kW(ind el) / R. Ihle ; K. Dielmann}, series = {Integrierte Energiesysteme : Chancen im Wettbewerb ; Tagung N{\"u}rnberg, 4. und 5. April 2000 / VDI-Gesellschaft Energietechnik. - (VDI-Berichte ; 1539)}, journal = {Integrierte Energiesysteme : Chancen im Wettbewerb ; Tagung N{\"u}rnberg, 4. und 5. April 2000 / VDI-Gesellschaft Energietechnik. - (VDI-Berichte ; 1539)}, publisher = {VDI-Verl.}, address = {D{\"u}sseldorf}, isbn = {3-18-091539-0}, pages = {245 -- 266}, year = {2000}, language = {de} } @article{DielmannCudinaMehlkopf2003, author = {Dielmann, Klaus-Peter and Cudina, Boris and Mehlkopf, Marcus}, title = {Einfluss der Brennstoffdaten auf die CO2-Inventarisierung : Handel mit Emissionsrechten}, series = {Euroheat and power : Kraft-W{\"a}rme-Kopplung, Nah-/Fernw{\"a}rme, Contracting}, volume = {32}, journal = {Euroheat and power : Kraft-W{\"a}rme-Kopplung, Nah-/Fernw{\"a}rme, Contracting}, number = {9}, isbn = {0949-166X}, pages = {22 -- 25}, year = {2003}, language = {de} } @article{DielmannBockSonnek2007, author = {Dielmann, Klaus-Peter and Bock, Alexis and Sonnek, Frederic}, title = {Stand der CO2-Allokationspl{\"a}ne in Europa und Durchsetzung der Monitoring-Richtlinien}, series = {VGB PowerTech : international journal for electricity and heat generation}, volume = {87}, journal = {VGB PowerTech : international journal for electricity and heat generation}, number = {3}, isbn = {1435-3199}, pages = {40 -- 46}, year = {2007}, language = {de} } @article{Dielmann2002, author = {Dielmann, Klaus-Peter}, title = {Kraft-W{\"a}rme-K{\"a}lte-Kopplung mit Mikrogasturbinen : Abschlussbericht ; [01.09.2000 - 31.01.2002]}, publisher = {Fachhochsch. Aachen, Abt. J{\"u}lich, FB 7, NOWUM-Energy}, address = {J{\"u}lich}, pages = {15 Bl : Ill., graph. Darst.}, year = {2002}, language = {de} } @article{Dielmann2001, author = {Dielmann, Klaus-Peter}, title = {Mikrogasturbinen : Technik und Anwendung}, series = {BWK : das Energie-Fachmagazin . 53 (2001), H. 6}, journal = {BWK : das Energie-Fachmagazin . 53 (2001), H. 6}, isbn = {0006-9612}, pages = {6 -- 9}, year = {2001}, language = {de} } @article{Dielmann2000, author = {Dielmann, Klaus-Peter}, title = {Mikro-Gasturbine als Kleinst-BHKW-Bericht {\"u}ber Einsatzerfahrungen}, series = {F{\"u}nftes VWEW-Fachforum Nahw{\"a}rme 2000 : W{\"a}rmedirekt-Service der Energiedienstleistungsunternehmen mit Fachausstellung Nahw{\"a}rmetechnik 2000 ; 4. und 5. Mai 2000 in Halle}, journal = {F{\"u}nftes VWEW-Fachforum Nahw{\"a}rme 2000 : W{\"a}rmedirekt-Service der Energiedienstleistungsunternehmen mit Fachausstellung Nahw{\"a}rmetechnik 2000 ; 4. und 5. Mai 2000 in Halle}, publisher = {VWEW}, address = {[Frankfurt, Main]}, pages = {5.1 -- 5.22}, year = {2000}, language = {de} } @article{DickhoffHorikawaFunke2021, author = {Dickhoff, Jens and Horikawa, Atsushi and Funke, Harald}, title = {Hydrogen Combustion - new DLE Combustor Addresses NOx Emissions and Flashback}, series = {Turbomachinery international : the global journal of energy equipment}, volume = {62}, journal = {Turbomachinery international : the global journal of energy equipment}, number = {4}, publisher = {MJH Life Sciences}, address = {Cranbury}, issn = {2767-2328}, pages = {26 -- 27}, year = {2021}, language = {en} } @article{DickWagnerRoeth2005, author = {Dick, Angela and Wagner, Manfred and R{\"o}th, Thilo}, title = {Capro Automotive Group FH Aachen}, year = {2005}, abstract = {Design- und Karosseriebaustudenten der FH Aachen entwickeln gemeinsam mit externen Fachleuten unter Einsatz virtueller Entwicklungswerkzeuge ein Konzept f{\"u}r einen Sportwagen}, subject = {Karosseriebau}, language = {de} } @article{DethloffKrollLudwigs2006, author = {Dethloff, Nina and Kroll-Ludwigs, Kathrin}, title = {The Constitutional Court as Driver of Reforms in German Family Law}, series = {International Survey of Family Law}, journal = {International Survey of Family Law}, pages = {217 -- 234}, year = {2006}, language = {en} } @article{DethloffKrollLudwigs2008, author = {Dethloff, Nina and Kroll-Ludwigs, Kathrin}, title = {Strengthening Children's Rights in German Family Law}, series = {The International Survey of Family Law}, journal = {The International Survey of Family Law}, pages = {119 -- 136}, year = {2008}, language = {en} } @article{DethloffKrollLudwigs2009, author = {Dethloff, Nina and Kroll-Ludwigs, Kathrin}, title = {A Lei de Parceria Registrada de 2001 e suas Reformas no Direito Alemao}, series = {Revista Brasileira de Direito das Fam{\´i}lias e Sucessoes}, volume = {11}, journal = {Revista Brasileira de Direito das Fam{\´i}lias e Sucessoes}, number = {12}, pages = {80 -- 94}, year = {2009}, language = {de} } @article{DesernoAachAmuntsetal.2011, author = {Deserno, Thomas M. and Aach, Til and Amunts, Katrin and Hillen, Walter and Kuhlen, Torsten and Scholl, Ingrid}, title = {Advances in medical image processing : A special Issue on the Workshop in Aachen, Germany, March 2010}, series = {Computer Science - Research and Development. 26 (2011), H. 1-2}, journal = {Computer Science - Research and Development. 26 (2011), H. 1-2}, publisher = {springer}, address = {Berlin}, isbn = {1865-2042}, pages = {1 -- 3}, year = {2011}, language = {en} } @article{DerschGeyerHerrmannetal.2004, author = {Dersch, J{\"u}rgen and Geyer, Michael and Herrmann, Ulf and Jones, Scott A. and Kelly, Bruce and Kistner, Rainer and Ortmanns, Winfried and Pitz-Paal, Robert and Price, Henry}, title = {Trough integration into power plants—a study on the performance and economy of integrated solar combined cycle systems}, series = {Energy : the international journal}, volume = {29}, journal = {Energy : the international journal}, number = {5-6 (Special Issue SolarPaces)}, issn = {0360-5442}, doi = {10.1016/S0360-5442(03)00199-3}, pages = {947 -- 959}, year = {2004}, language = {en} } @article{DeppeKlatteBongaertsetal.2011, author = {Deppe, Veronika Maria and Klatte, Stephanie and Bongaerts, Johannes and Maurer, Karl-Heinz and O'Connell, Timothy and Meinhardt, Friedhelm}, title = {Genetic control of Amadori product degradation in Bacillus subtilis via regulation of frlBONMD expression by FrlR}, series = {Applied and environmental microbiology}, volume = {Vol. 77}, journal = {Applied and environmental microbiology}, number = {No. 9}, publisher = {American Society of Mechanical Engineers (ASME)}, address = {New York}, issn = {1098-5336 (E-Journal); 0003-6919 (Print); 0099-2240 (Print)}, pages = {2839 -- 2846}, year = {2011}, language = {en} } @article{DeppeBongaertsO'Connelletal.2011, author = {Deppe, Veronika Maria and Bongaerts, Johannes and O'Connell, Timothy and Maurer, Karl-Heinz and Meinhardt, Friedhelm}, title = {Enzymatic deglycation of Amadori products in bacteria}, series = {Applied microbiology and biotechnology}, volume = {Vol. 90}, journal = {Applied microbiology and biotechnology}, number = {Iss. 2}, publisher = {Springer}, address = {Berlin}, issn = {1432-0614 (E-Journal); 0171-1741 (Print); 0175-7598 (Print); 0340-2118 (Print)}, pages = {399 -- 406}, year = {2011}, language = {en} } @article{DemnyHebel2014, author = {Demny, Andreas and Hebel, Christoph}, title = {Rechnergest{\"u}tzte Ermittlung der Verbindungsfunktionsstufen und der verbindungsbezogenen Angebotsqualit{\"a}t nach den Richtlinien f{\"u}r integrierte Netzgestaltung nach RIN 2008}, series = {Straßenverkehrstechnik : Organ der Forschungsgesellschaft f{\"u}r Straßen- und Verkehrswesen, der Bundesvereinigung der Straßenbau- und Verkehrsingenieure und der {\"O}sterreichischen Forschungsgesellschaft Straße und Verkehr ; Zeitschrift f{\"u}r Verkehrsplanung, Verkehrsmanagement, Verkehrssicherheit, Verkehrstechnik}, volume = {Jg. 58}, journal = {Straßenverkehrstechnik : Organ der Forschungsgesellschaft f{\"u}r Straßen- und Verkehrswesen, der Bundesvereinigung der Straßenbau- und Verkehrsingenieure und der {\"O}sterreichischen Forschungsgesellschaft Straße und Verkehr ; Zeitschrift f{\"u}r Verkehrsplanung, Verkehrsmanagement, Verkehrssicherheit, Verkehrstechnik}, number = {H. 12}, publisher = {Kirschbaum Verlag}, address = {Bonn}, issn = {0039-2219}, pages = {811 -- 820}, year = {2014}, language = {de} } @article{DemmerChowdhurySelmeretal.2017, author = {Demmer, Julius K. and Chowdhury, Nilanjan Pal and Selmer, Thorsten and Ermler, Ulrich and Buckel, Wolfgang}, title = {The semiquinone swing in the bifurcating electron transferring flavoprotein/butyryl-CoA dehydrogenase complex from Clostridium difficile}, series = {Nature Communications}, volume = {8}, journal = {Nature Communications}, number = {1}, issn = {2041-1723}, doi = {10.1038/s41467-017-01746-3}, pages = {1 -- 10}, year = {2017}, language = {en} } @article{DemirciKurulganDemirciTrzewiketal.2009, author = {Demirci, Taylan and Kurulgan Demirci, Eylem and Trzewik, J{\"u}rgen and Linder, Peter and Digel, Ilya and Artmann, Gerhard and Sakizli, Meral and Temiz Artmann, Ayseg{\"u}l}, title = {Gene expression profile analysis of 3T3/NIH fibroblasts after one hour mechanical stress}, series = {IUBMB Life. 61 (2009), H. 3}, journal = {IUBMB Life. 61 (2009), H. 3}, publisher = {Wiley-VCH}, address = {Weinheim}, isbn = {1521-6543}, pages = {311 -- 312}, year = {2009}, language = {en} } @article{DemirciTrzewikLinderetal.2004, author = {Demirci, T. and Trzewik, J. and Linder, Peter and Digel, Ilya and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l}, title = {Mechanical Stimulation of 3T3 Fibroblasts Activates Genes: ITGB5 and p53 Responses as Quantified on the mRNA Level}, series = {Biomedizinische Technik . 49 (2004), H. Erg.-Bd. 2}, journal = {Biomedizinische Technik . 49 (2004), H. Erg.-Bd. 2}, isbn = {0932-4666}, pages = {1030 -- 1031}, year = {2004}, language = {en} } @article{DemirciTrzewikLinderetal.2004, author = {Demirci, T. and Trzewik, J. and Linder, Peter and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l}, title = {Mechanical Stimulation of 3T3 Fibroblasts Activates Genes: Real Time PCR Products and Suppliers by Comparison}, series = {Biomedizinische Technik . 49 (2004), H. Erg.-Bd. 2}, journal = {Biomedizinische Technik . 49 (2004), H. Erg.-Bd. 2}, isbn = {0932-4666}, pages = {1046 -- 1047}, year = {2004}, language = {en} } @article{DellmannGloriusLitvinovetal.2023, author = {Dellmann, Sophia Florence and Glorius, J. and Litvinov, Yu A. and Reifarth, R. and Al-Khasawneh, Kafa and Aliotta, M. and Bott, L. and Br{\"u}ckner, Benjamin and Bruno, C. G. and Chen, Ruijiu and Davinson, T. and Dickel, T. and Dillmann, Iris and Dmytriev, D. and Erbacher, P. and Freire-Fern{\´a}ndez, D. and Forstner, Oliver and Geissel, H. and G{\"o}bel, K. and Griffin, Christopher J. and Grisenti, R. and Gumberidze, Alexandre and Haettner, Emma and Hagmann, Siegbert and Heil, M. and Heß, R. and Hillenbrand, P.-M. and Joseph, R. and Jurado, B. and Kozhuharov, Christophor and Kulikov, I. and L{\"o}her, Bastian and Langer, Christoph and Leckenby, Guy and Lederer-Woods, C. and Lestinsky, M. and Litvinov, S. A. and Lorenz, B. A. and Lorenz, E. and Marsh, J. and Menz, Esther Babette and Morgenroth, T. and Petridis, N. and Pibernat, Jerome and Popp, U. and Psaltis, Athanasios and Sanjari, Shahab and Scheidenberger, C. and Sguazzin, M. and Sidhu, Ragandeep Singh and Spillmann, Uwe and Steck, M. and St{\"o}hlker, T. and Surzhykov, A. and Swartz, J. A. and T{\"o}rnqvist, H. and Varga, L. and Vescovi, Diego and Weick, H. and Weigand, M. and Woods, P. and Xing, Y. and Yamaguchi, Taiyo}, title = {Proton capture on stored radioactive ¹¹⁸Te ions}, series = {EPJ Web of Conferences}, volume = {279}, journal = {EPJ Web of Conferences}, number = {Article Number: 11018}, publisher = {EDP Sciences}, issn = {2100-014X}, doi = {10.1051/epjconf/202327911018}, pages = {1 -- 5}, year = {2023}, abstract = {Experimental determination of the cross sections of proton capture on radioactive nuclei is extremely difficult. Therefore, it is of substantial interest for the understanding of the production of the p-nuclei. For the first time, a direct measurement of proton-capture cross sections on stored, radioactive ions became possible in an energy range of interest for nuclear astrophysics. The experiment was performed at the Experimental Storage Ring (ESR) at GSI by making use of a sensitive method to measure (p,γ) and (p,n) reactions in inverse kinematics. These reaction channels are of high relevance for the nucleosyn-thesis processes in supernovae, which are among the most violent explosions in the universe and are not yet well understood. The cross section of the ¹¹⁸Te(p,γ) reaction has been measured at energies of 6 MeV/u and 7 MeV/u. The heavy ions interacted with a hydrogen gas jet target. The radiative recombination process of the fully stripped ¹¹⁸Te ions and electrons from the hydrogen target was used as a luminosity monitor. An overview of the experimental method and preliminary results from the ongoing analysis will be presented.}, language = {en} } @article{DelleHuckBaeckeretal.2015, author = {Delle, Lotta E. and Huck, Christina and B{\"a}cker, Matthias and M{\"u}ller, Frank and Grandthyll, Samuel and Jacobs, Karin and Lilischkis, Rainer and Vu, Xuan T. and Sch{\"o}ning, Michael Josef and Wagner, Patrick and Thoelen, Roland and Weil, Maryam and Ingebrandt, Sven}, title = {Impedimetric immunosensor for the detection of histamine based on reduced graphene oxide}, series = {Physica status solidi (a)}, volume = {212}, journal = {Physica status solidi (a)}, number = {6}, publisher = {Wiley}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201431863}, pages = {1327 -- 1334}, year = {2015}, language = {en} } @article{Delaittre2019, author = {Delaittre, Guillaume}, title = {Telechelic Poly(2-Oxazoline)s}, series = {European Polymer Journal}, journal = {European Polymer Journal}, number = {In Press, Journal Pre-proof, 109281}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0014-3057}, doi = {10.1016/j.eurpolymj.2019.109281}, year = {2019}, language = {en} } @article{DegeringEggertPulsetal.2010, author = {Degering, Christian and Eggert, Thorsten and Puls, Michael and Bongaerts, Johannes and Evers, Stefan and Maurer, Karl-Heinz and Jaeger, Karl-Erich}, title = {Optimization of protease secretion in Bacillus subtilis and Bacillus licheniformis by screening of homologous and herologous signal peptides}, series = {Applied and environmental microbiology}, volume = {76}, journal = {Applied and environmental microbiology}, number = {19}, publisher = {American Society for Microbiology}, address = {Washington, DC}, issn = {1098-5336 (E-Journal); 0003-6919 (Print); 0099-2240 (Print)}, doi = {10.1128/AEM.01146-10}, pages = {6370 -- 6378}, year = {2010}, abstract = {Bacillus subtilis and Bacillus licheniformis are widely used for the large-scale industrial production of proteins. These strains can efficiently secrete proteins into the culture medium using the general secretion (Sec) pathway. A characteristic feature of all secreted proteins is their N-terminal signal peptides, which are recognized by the secretion machinery. Here, we have studied the production of an industrially important secreted protease, namely, subtilisin BPN′ from Bacillus amyloliquefaciens. One hundred seventy-three signal peptides originating from B. subtilis and 220 signal peptides from the B. licheniformis type strain were fused to this secretion target and expressed in B. subtilis, and the resulting library was analyzed by high-throughput screening for extracellular proteolytic activity. We have identified a number of signal peptides originating from both organisms which produced significantly increased yield of the secreted protease. Interestingly, we observed that levels of extracellular protease were improved not only in B. subtilis, which was used as the screening host, but also in two different B. licheniformis strains. To date, it is impossible to predict which signal peptide will result in better secretion and thus an improved yield of a given extracellular target protein. Our data show that screening a library consisting of homologous and heterologous signal peptides fused to a target protein can identify more-effective signal peptides, resulting in improved protein export not only in the original screening host but also in different production strains.}, language = {en} } @article{DefosseKleinschmidtSchmutzetal.2022, author = {Defosse, Jerome and Kleinschmidt, Joris and Schmutz, Axel and Loop, Torsten and Staat, Manfred and Gatzweiler, Karl-Heinz and Wappler, Frank and Schieren, Mark}, title = {Dental strain on maxillary incisors during tracheal intubation with double-lumen tubes and different laryngoscopy techniques - a blinded manikin study}, series = {Journal of Cardiothoracic and Vascular Anesthesia}, volume = {36}, journal = {Journal of Cardiothoracic and Vascular Anesthesia}, number = {8, Part B}, publisher = {Elsevier}, address = {New York, NY}, issn = {1053-0770}, doi = {10.1053/j.jvca.2022.02.017}, pages = {3021 -- 3027}, year = {2022}, language = {en} } @article{deBloisdeZangerPaulssenetal.2018, author = {de Blois, Eric and de Zanger, Rory M. S. and Paulßen, Elisabeth and Sze Chan, Ho and Breeman, Wouter A. P.}, title = {Semi-automated system for concentrating 68Ga-eluate to obtain high molar and volume concentration of 68Ga-Radiopharmaca for preclinical applications}, series = {Nuclear Medicine and Biology}, volume = {64-65}, journal = {Nuclear Medicine and Biology}, publisher = {Elsevier}, address = {Amsterdam}, doi = {10.1016/j.nucmedbio.2018.06.006}, pages = {16 -- 21}, year = {2018}, abstract = {68Ga-radiopharmaceuticals are common in the field of Nuclear Medicine to visualize receptor-mediated processes. In contrast to straightforward labeling procedures for clinical applications, preclinical in vitro and in vivo applications are hampered for reasons like e.g. volume restriction, activity concentration, molar activity and osmolality. Therefore, we developed a semiautomatic system specifically to overcome these problems. A difficulty appeared unexpectedly, as intrinsic trace metals derived from eluate (Zn, Fe and Cu) are concentrated as well in amounts that influence radiochemical yield and thus lower molar activity.}, language = {en} } @article{DashevskyLanzlKotliar2011, author = {Dashevsky, Alexey V. and Lanzl, Ines M. and Kotliar, Konstantin}, title = {Non-penetrating intracanalicular partial trabeculectomy via the ostia of Schlemm's canal}, series = {Graefe's Archive for Clinical and Experimental Ophthalmology}, volume = {249}, journal = {Graefe's Archive for Clinical and Experimental Ophthalmology}, number = {4}, publisher = {Springer}, address = {Berlin}, issn = {0721-832x}, pages = {565 -- 573}, year = {2011}, language = {en} } @article{DarmoSchaefferFoersteretal.2000, author = {Darmo, J. and Sch{\"a}ffer, F. and F{\"o}rster, Arnold and Kordos, P.}, title = {Beryllium doped low-temperature-grown MBE GaAs: material for photomixing in the THz frequency range}, series = {ASDAM 2000 : conference proceedings / edited by Jozef Osvald ... [et al.]}, journal = {ASDAM 2000 : conference proceedings / edited by Jozef Osvald ... [et al.]}, publisher = {IEEE}, address = {Piscataway, NJ}, isbn = {0780359399}, pages = {147 -- 150}, year = {2000}, language = {en} } @article{DantismTakenagaWagneretal.2017, author = {Dantism, Shahriar and Takenaga, Shoko and Wagner, Torsten and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Differential imaging of the metabolism of bacteria and eukaryotic cells based on light-addressable potentiometric sensors}, series = {Electrochimica Acta}, volume = {246}, journal = {Electrochimica Acta}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0013-4686}, doi = {10.1016/j.electacta.2017.05.196}, pages = {234 -- 241}, year = {2017}, abstract = {A light-addressable potentiometric sensor (LAPS) is a field-effect-based potentiometric sensor with an electrolyte/insulator/semiconductor (EIS) structure, which is able to monitor analyte concentrations of (bio-)chemical species in aqueous solutions in a spatially resolved way. Therefore, it is also an appropriate tool to record 2D-chemical images of concentration variations on the sensor surface. In the present work, two differential, LAPS-based measurement principles are introduced to determine the metabolic activity of Escherichia coli (E. coli) K12 and Chinese hamster ovary (CHO) cells as test microorganisms. Hereby, we focus on i) the determination of the extracellular acidification rate (ΔpH/min) after adding glucose solutions to the cell suspensions; and ii) recording the amplitude increase of the photocurrent (Iph) related to the produced acids from E. coli K12 bacteria and CHO cells on the sensor surface by 2D-chemical imaging. For this purpose, 3D-printed multi-chamber structures were developed and mounted on the planar sensor-chip surface to define four independent compartments, enabling differential measurements with varying cell concentrations. The differential concept allows eliminating unwanted drift effects and, with the four-chamber structures, measurements on the different cell concentrations were performed simultaneously, thus reducing also the overall measuring time.}, language = {en} } @article{DantismTakenagaWagneretal.2016, author = {Dantism, Shahriar and Takenaga, Shoko and Wagner, Patrick and Wagner, Torsten and Sch{\"o}ning, Michael Josef}, title = {Determination of the extracellular acidification of Escherichia coli K12 with a multi-​chamber-​based LAPS system}, series = {Physica status solidi (a)}, volume = {213}, journal = {Physica status solidi (a)}, number = {6}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6300}, doi = {10.1002/pssa.201533043}, pages = {1479 -- 1485}, year = {2016}, abstract = {On-line monitoring of the metabolic activity of microorganisms involved in intermediate stages of biogas production plays an important role to avoid undesirable "down times" during the biogas production. In order to control this process, an on-chip differential measuring system based on the light-addressable potentiometric sensor (LAPS) principle combined with a 3D-printed multi-chamber structure has been realized. As a test microorganism, Escherichia coli K12 (E. coli K12) were used for cell-based measurements. Multi-chamber structures were developed to determine the metabolic activity of E. coli K12 in suspension for a different number of cells, responding to the addition of a constant or variable amount of glucose concentrations, enabling differential and simultaneous measurements.}, language = {en} } @article{DantismRoehlenWagneretal.2018, author = {Dantism, Shahriar and R{\"o}hlen, Desiree and Wagner, Torsten and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Optimization of Cell-Based Multi-Chamber LAPS Measurements Utilizing FPGA-Controlled Laser-Diode Modules}, series = {physica status solidi a : applications and materials sciences}, volume = {215}, journal = {physica status solidi a : applications and materials sciences}, number = {15}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201800058}, pages = {Article number 1800058}, year = {2018}, abstract = {A light-addressable potentiometric sensor (LAPS) is a field-effect-based potentiometric device, which detects concentration changes of an analyte solution on the sensor surface in a spatially resolved way. It uses a light source to generate electron-hole pairs inside the semiconductor, which are separated in the depletion region due to an applied bias voltage across the sensor structure and hence, a surface-potential-dependent photocurrent can be read out. However, depending on the beam angle of the light source, scattering effects can occur, which influence the recorded signal in LAPS-based differential measurements. To solve this problem, a novel illumination unit based on a field programmable gate array (FPGA) consisting of 16 small-sized tunable infrared laser-diode modules (LDMs) is developed. Due to the improved focus of the LDMs with a beam angle of only 2 mrad, undesirable scattering effects are minimized. Escherichia coli (E. coli) K12 bacteria are used as a test microorganism to study the extracellular acidification on the sensor surface. Furthermore, a salt bridge chamber is built up and integrated with the LAPS system enabling multi-chamber differential measurements with a single Ag/AgCl reference electrode.}, language = {en} } @article{DantismRoehlenWagneretal.2019, author = {Dantism, Shahriar and R{\"o}hlen, Desiree and Wagner, Torsten and Wagner, P. and Sch{\"o}ning, Michael Josef}, title = {A LAPS-based differential sensor for parallelized metabolism monitoring of various bacteria}, series = {Sensors}, volume = {19}, journal = {Sensors}, number = {21}, publisher = {MDPI}, address = {Basel}, issn = {1424-8220}, doi = {10.3390/s19214692}, pages = {Artikel 4692}, year = {2019}, abstract = {Monitoring the cellular metabolism of bacteria in (bio)fermentation processes is crucial to control and steer them, and to prevent undesired disturbances linked to metabolically inactive microorganisms. In this context, cell-based biosensors can play an important role to improve the quality and increase the yield of such processes. This work describes the simultaneous analysis of the metabolic behavior of three different types of bacteria by means of a differential light-addressable potentiometric sensor (LAPS) set-up. The study includes Lactobacillus brevis, Corynebacterium glutamicum, and Escherichia coli, which are often applied in fermentation processes in bioreactors. Differential measurements were carried out to compensate undesirable influences such as sensor signal drift, and pH value variation during the measurements. Furthermore, calibration curves of the cellular metabolism were established as a function of the glucose concentration or cell number variation with all three model microorganisms. In this context, simultaneous (bio)sensing with the multi-organism LAPS-based set-up can open new possibilities for a cost-effective, rapid detection of the extracellular acidification of bacteria on a single sensor chip. It can be applied to evaluate the metabolic response of bacteria populations in a (bio)fermentation process, for instance, in the biogas fermentation process.}, language = {en} } @article{DantismRoehlenSelmeretal.2019, author = {Dantism, Shahriar and R{\"o}hlen, Desiree and Selmer, Thorsten and Wagner, Torsten and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Quantitative differential monitoring of the metabolic activity of Corynebacterium glutamicum cultures utilizing a light-addressable potentiometric sensor system}, series = {Biosensors and Bioelectronics}, volume = {139}, journal = {Biosensors and Bioelectronics}, publisher = {Elsevier}, address = {Amsterdam}, doi = {10.1016/j.bios.2019.111332}, pages = {Artikel 111332}, year = {2019}, language = {en} } @article{DantismRoehlenDahmenetal.2020, author = {Dantism, Shahriar and R{\"o}hlen, Desiree and Dahmen, Markus and Wagner, Torsten and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {LAPS-based monitoring of metabolic responses of bacterial cultures in a paper fermentation broth}, series = {Sensors and Actuators B: Chemical}, volume = {320}, journal = {Sensors and Actuators B: Chemical}, number = {Art. 128232}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2020.128232}, year = {2020}, abstract = {As an alternative renewable energy source, methane production in biogas plants is gaining more and more attention. Biomass in a bioreactor contains different types of microorganisms, which should be considered in terms of process-stability control. Metabolically inactive microorganisms within the fermentation process can lead to undesirable, time-consuming and cost-intensive interventions. Hence, monitoring of the cellular metabolism of bacterial populations in a fermentation broth is crucial to improve the biogas production, operation efficiency, and sustainability. In this work, the extracellular acidification of bacteria in a paper-fermentation broth is monitored after glucose uptake, utilizing a differential light-addressable potentiometric sensor (LAPS) system. The LAPS system is loaded with three different model microorganisms (Escherichia coli, Corynebacterium glutamicum, and Lactobacillus brevis) and the effect of the fermentation broth at different process stages on the metabolism of these bacteria is studied. In this way, different signal patterns related to the metabolic response of microorganisms can be identified. By means of calibration curves after glucose uptake, the overall extracellular acidification of bacterial populations within the fermentation process can be evaluated.}, language = {en} } @article{DantismTakenagaWagneretal.2015, author = {Dantism, S. and Takenaga, S. and Wagner, P. and Wagner, Torsten and Sch{\"o}ning, Michael Josef}, title = {Light-addressable Potentiometric Sensor (LAPS) Combined with Multi-chamber Structures to Investigate the Metabolic Activity of Cells}, series = {Procedia Engineering}, volume = {120}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2015.08.647}, pages = {384 -- 387}, year = {2015}, abstract = {LAPS are field-effect-based potentiometric sensors which are able to monitor analyte concentrations in a spatially resolved manner. Hence, a LAPS sensor system is a powerful device to record chemical imaging of the concentration of chemical species in an aqueous solution, chemical reactions, or the growth of cell colonies on the sensor surface, to record chemical images. In this work, multi-chamber 3D-printed structures made out of polymer (PP-ABS) were combined with LAPS chips to analyse differentially and simultaneously the metabolic activity of Escherichia coli K12 and Chinese hamster ovary (CHO) cells, and the responds of those cells to the addition of glucose solution.}, language = {en} } @article{DankelmannHellwigVolkmann2009, author = {Dankelmann, Peter and Hellwig, Angelika and Volkmann, Lutz}, title = {Inverse degree and edge-connectivity}, series = {Discrete mathematics}, volume = {Vol. 309}, journal = {Discrete mathematics}, number = {Iss. 9}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1872-681X (E-Journal); 0012-365X (Print)}, pages = {2943 -- 2947}, year = {2009}, language = {en} } @article{DankelmannHellwigVolkmann2007, author = {Dankelmann, Peter and Hellwig, Angelika and Volkmann, Lutz}, title = {On the connectivity of diamond-free graphs}, series = {Discrete applied mathematics}, volume = {Vol. 155}, journal = {Discrete applied mathematics}, number = {Iss. 16}, issn = {0166-218X (E-Journal); 1872-6771 (E-Journal); 0166-218X (Print)}, pages = {2111 -- 2117}, year = {2007}, language = {en} } @article{DanielStarck2007, author = {Daniel, Bernd and Starck, Andreas}, title = {Die Anwendung der VOB in der baubetrieblichen Praxis}, year = {2007}, abstract = {Eine Einf{\"u}hrung in die Anwendung der VOB in der baubetrieblichen Praxis im Rahmen der erg{\"a}nzenden Schriften zu den Vorlesungen. Die Anwendung der VOB als Vertragsbedingung f{\"u}r einen Bauvertrag ist g{\"a}ngige Praxis, {\"u}ber die der Architekt im Baubetrieb umfassend informiert sein muß. Die Anwendung der VOB im Bauvertrag bedarf der vorherigen Vereinbarung zwischen den Vertragsparteien. Dabei muß die VOB im Ganzen vereinbart werden. Eine Ver{\"a}nderung dieser Bestimmungen f{\"u}hrt zur teilweisen Unwirksamkeit der vertraglichen Vereinbarung. Der Architekt, der f{\"u}r seinen Bauherrn die Vergabeunterlagen zusammenstellen muß, haftet f{\"u}r Fehler bei der Formulierung oder der Zusammenstellung. Es ist daher f{\"u}r den Architekten unerl{\"a}ßlich, die vertraglichen Zusammenh{\"a}nge zu kennen. Dieser Fachaufsatz soll zu einem sicheren Umgang mit der VOB als Vertragsgrundlage beitragen.}, subject = {Baubetrieb}, language = {de} } @article{DanielStarck2007, author = {Daniel, Bernd and Starck, Andreas}, title = {Kostenkontrolle und Kostensteuerung im Hochbau}, year = {2007}, abstract = {Textauszug: Nach dem Leistungsbild der HOAI hat der Architekt bei Planung und Baubetrieb vier Stationen der Kostenermittlung entsprechend der DIN 276, Abschnitt 2.3 abzuarbeiten. Der Architekt, der seiner Verantwortung gerecht werden will, wird hier weitere Kontrollmechanismen einbauen wollen. {\"U}ber die genannten Kostenermittlungen hinaus kennt die DIN 276 daher noch das Erfordernis der Kostenkontrolle in Abschnitt 2.4 und der Kostensteuerung in Abschnitt 2.5. Die Kostensteuerung greift immer dann, wenn die Kostenkontrolle eine Abweichung des Kostenrahmens von den Sollwerten aufzeigt. Dazu m{\"u}ssen die Kontrollinstanzen dort eingebaut werden, wo Korrekturen noch m{\"o}glich sind. Eine erste Kontrolle der Kosten ist daher zwischen Massenermittlung und Vergabe sinnvoll einzuflechten. Zu diesem Zeitpunkt kann die Planung noch ver{\"a}ndert werden, was einen ersten steuernden Eingriff in die Baukosten erm{\"o}glicht, und zwar bevor die Angebotsunterlagen verschickt werden. Die Grundlagen zu einer effektiven Kostensteuerung werden in der Mengenermittlung der Leistungsphase 6 gelegt. Wenn dort die Mengen nicht sorgf{\"a}ltig und nachvollziehbar ermittelt wurden, wird der Soll- Ist- Abgleich w{\"a}hrend der Bauphase nicht fr{\"u}hzeitig genug gelingen, wenn nicht gar ganz entfallen. Es gilt also, daf{\"u}r zu sorgen, dass die Mengenermittlung zur Vergabe mit entsprechender Sorgfalt und vor Allem „projektnah" erfolgt. Sch{\"a}tzungen haben hier keine Berechtigung.}, subject = {Projektsteuerung}, language = {de} } @article{DanhoNaithaniSasakietal.1980, author = {Danho, Waleed and Naithani, Vinod K. and Sasaki, Andr{\´e} N. and F{\"o}hles, Joseph and Berndt, Heinz and B{\"u}llesbach, Erika E. and Zahn, H.}, title = {Human proinsulin, VII : synthesis of two protected peptides corresponding to the sequences 1—45 and 46—86 of the prohormone}, series = {Hoppe-Seyler's Zeitschrift f{\"u}r physiologische Chemie}, volume = {361}, journal = {Hoppe-Seyler's Zeitschrift f{\"u}r physiologische Chemie}, number = {1}, issn = {1437-4315}, doi = {10.1515/bchm2.1980.361.1.857}, pages = {857 -- 863}, year = {1980}, language = {en} } @article{Damrau1999, author = {Damrau, Karin}, title = {Beyond Solidity - Inventions, Spaces and Concepts for the Elements of Air and Water}, series = {Architectural design : AD. 69 (1999), H. 3-4}, journal = {Architectural design : AD. 69 (1999), H. 3-4}, isbn = {0003-8504}, pages = {22 -- 33}, year = {1999}, language = {en} } @article{Damrau2000, author = {Damrau, Karin}, title = {Fantastic Spatial Combinations in Film}, series = {Architectural design : AD. 70 (2000), H. 1}, journal = {Architectural design : AD. 70 (2000), H. 1}, isbn = {0003-8504}, pages = {58 -- 61}, year = {2000}, language = {en} } @article{DammSauerbornFendetal.2017, author = {Damm, Marc Andr{\´e} and Sauerborn, Markus and Fend, Thomas and Herrmann, Ulf}, title = {Optimisation of a urea selective catalytic reduction system with a coated ceramic mixing element}, series = {Journal of ceramic science and technology}, volume = {8}, journal = {Journal of ceramic science and technology}, number = {1}, publisher = {G{\"o}ller}, address = {Baden-Baden}, isbn = {2190-9385 (Print)}, issn = {2190-9385 (Online)}, doi = {10.4416/JCST2016-00056}, pages = {19 -- 24}, year = {2017}, language = {en} } @article{DammErlerHillenetal.2011, author = {Damm, Alexander and Erler, Andr{\´e} and Hillen, Walter and Meroni, Michele and Schaepman, Michael E. and Verhoef, Wout and Rascher, Uwe}, title = {Modeling the impact of spectral sensor configurations on the FLD retrieval accuracy of sun-induced chlorophyll fluorescence}, series = {Remote Sensing of Environment}, volume = {115}, journal = {Remote Sensing of Environment}, number = {8}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {0034-4257}, pages = {1882 -- 1892}, year = {2011}, language = {en} } @article{DallasSalphatiGomezZepedaetal.2016, author = {Dallas, Shannon and Salphati, Laurent and Gomez-Zepeda, David and Wanek, Thomas and Chen, Liangfu and Chu, Xiaoyan and Kunta, Jeevan and Mezler, Mario and Menet, Marie-Claude and Chasseigneaux, Stephanie and Decl{\`e}ves, Xavier and Langer, Oliver and Pierre, Esaie and DiLoreto, Karen and Hoft, Carolin and Laplanche, Loic and Pang, Jodie and Pereira, Tony and Andonian, Clara and Simic, Damir and Rode, Anja and Yabut, Jocelyn and Zhang, Xiaolin and Scheer, Nico}, title = {Generation and Characterization of a Breast Cancer Resistance Protein Humanized Mouse Model}, series = {Molecular Pharmacology}, volume = {89}, journal = {Molecular Pharmacology}, number = {5}, publisher = {ASPET}, address = {Bethesda, Md.}, issn = {1521-0111}, doi = {10.1124/mol.115.102079}, pages = {492 -- 504}, year = {2016}, abstract = {Breast cancer resistance protein (BCRP) is expressed in various tissues, such as the gut, liver, kidney and blood brain barrier (BBB), where it mediates the unidirectional transport of substrates to the apical/luminal side of polarized cells. Thereby BCRP acts as an efflux pump, mediating the elimination or restricting the entry of endogenous compounds or xenobiotics into tissues and it plays important roles in drug disposition, efficacy and safety. Bcrp knockout mice (Bcrp-/-) have been used widely to study the role of this transporter in limiting intestinal absorption and brain penetration of substrate compounds. Here we describe the first generation and characterization of a mouse line humanized for BCRP (hBCRP), in which the mouse coding sequence from the start to stop codon was replaced with the corresponding human genomic region, such that the human transporter is expressed under control of the murine Bcrp promoter. We demonstrate robust human and loss of mouse BCRP/Bcrp mRNA and protein expression in the hBCRP mice and the absence of major compensatory changes in the expression of other genes involved in drug metabolism and disposition. Pharmacokinetic and brain distribution studies with several BCRP probe substrates confirmed the functional activity of the human transporter in these mice. Furthermore, we provide practical examples for the use of hBCRP mice to study drug-drug interactions (DDIs). The hBCRP mouse is a promising model to study the in vivo role of human BCRP in limiting absorption and BBB penetration of substrate compounds and to investigate clinically relevant DDIs involving BCRP.}, language = {en} } @article{DahmannMager1994, author = {Dahmann, Peter and Mager, M.}, title = {Einfluß der Zusammensetzung der abzuscheidenden Verschmutzung auf die Abscheideleistung von Hydraulikfiltern}, series = {{\"O}lhydraulik und Pneumatik. 38 (1994), H. 4}, journal = {{\"O}lhydraulik und Pneumatik. 38 (1994), H. 4}, isbn = {0341-2660}, pages = {212 -- 214}, year = {1994}, language = {de} } @article{DahmannHagemeisterNageletal.2006, author = {Dahmann, Peter and Hagemeister, Wilhelm and Nagel, G{\"u}nther and Exner, Peter}, title = {Geregelte Innenzahnradpumpe im Mehrquadrantenbetrieb Geschwindigkeits- und Positionsregelung eines hydraulischen Handlingger{\"a}tes}, series = {O+P {\"O}lhydraulik und Pneumatik. 24 (2006), H. 1}, journal = {O+P {\"O}lhydraulik und Pneumatik. 24 (2006), H. 1}, isbn = {0341-2660}, pages = {24 -- 28}, year = {2006}, language = {de} } @article{DahmannHagemeisterNageletal.2002, author = {Dahmann, Peter and Hagemeister, W. and Nagel, and Exner,}, title = {Geschwindigkeits- und Positionsregelung eines hydraulischen Handlingger{\"a}tes in einem Ziegelwerk durch frequenzgeregelte Innenzahnradpumpe im Mehrquadrantenbetrieb}, series = {Fluid power focused on applications : 3rd International Fluid Power Conference (3rd IFK) ; [conference proceedings, March 5th and 6th 2002, Aachen, Germany]. Fluidtechnik, Band T3}, journal = {Fluid power focused on applications : 3rd International Fluid Power Conference (3rd IFK) ; [conference proceedings, March 5th and 6th 2002, Aachen, Germany]. Fluidtechnik, Band T3}, publisher = {Shaker}, address = {Aachen}, isbn = {3-8265-9900-4}, pages = {83 -- 94}, year = {2002}, language = {de} } @article{Dahmann1995, author = {Dahmann, Peter}, title = {Offen f{\"u}r neue Modelle. GL-Hydraulik setzt neues Simulationssystem ein}, series = {Fluid Heft Sonderpublikation Fluid-Technik. 29 (1995)}, journal = {Fluid Heft Sonderpublikation Fluid-Technik. 29 (1995)}, isbn = {0015-461X}, pages = {8 -- 10}, year = {1995}, language = {de} } @article{Dahmann1990, author = {Dahmann, Peter}, title = {Leistungsf{\"a}higkeit von Hydraulikfiltern bei unterschiedlichen Betriebsbedingungen}, series = {{\"O}lhydraulik und Pneumatik. 34 (1990), H. 10}, journal = {{\"O}lhydraulik und Pneumatik. 34 (1990), H. 10}, isbn = {0341-2660}, pages = {682 -- 688}, year = {1990}, language = {de} } @article{Dahmann1993, author = {Dahmann, Peter}, title = {Funktionsweise von Hydraulikfiltern}, series = {{\"O}lhydraulik und Pneumatik. 37 (1993), H. 2}, journal = {{\"O}lhydraulik und Pneumatik. 37 (1993), H. 2}, isbn = {0341-2660}, pages = {118 -- 122}, year = {1993}, language = {de} } @article{DahlSuttrop1998, author = {Dahl, G{\"u}nter and Suttrop, F.}, title = {Engine control and low-NO(x) combustion for hydrogen fuelled aircraft gas turbines}, series = {International Journal of Hydrogen Energy. 23 (1998), H. 8}, journal = {International Journal of Hydrogen Energy. 23 (1998), H. 8}, isbn = {0360-3199}, pages = {695 -- 704}, year = {1998}, language = {en} } @article{DadfarCamozziDarguzyteetal.2020, author = {Dadfar, Dryed Mohammadali and Camozzi, Denise and Darguzyte, Milita and Roemhild, Karolin and Varvar{\`a}, Paola and Metselaar, Josbert and Banala, Srinivas and Straub, Marcel and G{\"u}ver, Nihan and Engelmann, Ulrich M. and Slabu, Ioana and Buhl, Miriam and Leusen, Jan van and K{\"o}gerler, Paul and Hermanns-Sachweh, Benita and Schulz, Volkmar and Kiessling, Fabian and Lammers, Twan}, title = {Size-isolation of superparamagnetic iron oxide nanoparticles improves MRI, MPI and hyperthermia performance}, series = {Journal of Nanobiotechnology}, volume = {18}, journal = {Journal of Nanobiotechnology}, number = {Article number 22}, publisher = {Nature Portfolio}, issn = {1477-3155}, doi = {10.1186/s12951-020-0580-1}, pages = {1 -- 13}, year = {2020}, abstract = {Superparamagnetic iron oxide nanoparticles (SPION) are extensively used for magnetic resonance imaging (MRI) and magnetic particle imaging (MPI), as well as for magnetic fluid hyperthermia (MFH). We here describe a sequential centrifugation protocol to obtain SPION with well-defined sizes from a polydisperse SPION starting formulation, synthesized using the routinely employed co-precipitation technique. Transmission electron microscopy, dynamic light scattering and nanoparticle tracking analyses show that the SPION fractions obtained upon size-isolation are well-defined and almost monodisperse. MRI, MPI and MFH analyses demonstrate improved imaging and hyperthermia performance for size-isolated SPION as compared to the polydisperse starting mixture, as well as to commercial and clinically used iron oxide nanoparticle formulations, such as Resovist® and Sinerem®. The size-isolation protocol presented here may help to identify SPION with optimal properties for diagnostic, therapeutic and theranostic applications.}, language = {en} }