@article{FoersterTillmannGerthsen1995, author = {F{\"o}rster, Arnold and Tillmann, K. and Gerthsen, D.}, title = {Morphological transformations of MBE-grown In0.6Ga0.4As island on GaAs(001) substrates / K. Tillmann ; D. Gerthsen ; P. Pfundstein ; A. F{\"o}rster ...}, series = {Microscopy of semiconducting materials 1995 : proceedings of the Institute of Physics Conference held at Oxford University, 20 - 23 March 1995 / Ed. by A G Cullis ... - (Conference series / Institute of Physics ; 146)}, journal = {Microscopy of semiconducting materials 1995 : proceedings of the Institute of Physics Conference held at Oxford University, 20 - 23 March 1995 / Ed. by A G Cullis ... - (Conference series / Institute of Physics ; 146)}, publisher = {Institute of Physics}, address = {Bristol [u.a.]}, isbn = {0-7503-0347-6}, pages = {195 -- ff.}, year = {1995}, language = {en} } @article{BeckBuchleitnerFerreinetal.2014, author = {Beck, Daniel and Buchleitner, Martin and Ferrein, Alexander and Niem{\"u}ller, Tim and Steinbauer, Gerald}, title = {Mostly Harmless \& AllemaniACs - mixed innovations}, pages = {1 -- 8}, year = {2014}, language = {en} } @inproceedings{BindzusBragard2018, author = {Bindzus, Manuel and Bragard, Michael}, title = {Motivating Intuitive Understanding of the Switched Reluctance Machine in the Education of Undergraduate Students}, series = {2018 IEEE 59th International Scientific Conference on Power and Electrical Engineering of Riga Technical University (RTUCON)}, booktitle = {2018 IEEE 59th International Scientific Conference on Power and Electrical Engineering of Riga Technical University (RTUCON)}, isbn = {978-1-5386-6903-7}, doi = {10.1109/RTUCON.2018.8659870}, pages = {1 -- 6}, year = {2018}, language = {en} } @inproceedings{Wessling2007, author = {Weßling, Matthias}, title = {Motivation and Leadership - The Reiss-Profile of the 16 Basic Desires: Research results and managerial applications}, year = {2007}, abstract = {Recent Results of the scientific Reiss-Profile (16 basic desires) due to the concept of Prof. Dr. Steven Reiss (State University Ohio, U.S.A.), supplemented by the comparative analysis of empirical motivational profiles of european executives of various companies.}, subject = {Motivation}, language = {en} } @inproceedings{BragardHoekHoegenetal.2018, author = {Bragard, Michael and Hoek, Hauke van and Hoegen, Anne von and Doncker, Rik W. De}, title = {Motivation-based Learning: Teaching Fundamentals of Electrical Engineering with an LED Spinning Top}, series = {2018 IEEE 59th International Scientific Conference on Power and Electrical Engineering of Riga Technical University (RTUCON)}, booktitle = {2018 IEEE 59th International Scientific Conference on Power and Electrical Engineering of Riga Technical University (RTUCON)}, isbn = {978-1-5386-6903-7}, doi = {10.1109/RTUCON.2018.8659810}, pages = {1 -- 6}, year = {2018}, language = {en} } @article{BiewendtBlaschkeBoehnert2021, author = {Biewendt, Marcel and Blaschke, Florian and B{\"o}hnert, Arno}, title = {Motivational factors in organisational change}, series = {SocioEconomic Challenges}, volume = {5}, journal = {SocioEconomic Challenges}, number = {3}, publisher = {ARMG}, address = {Sumy}, issn = {2520-6214}, doi = {10.21272/sec.5(3).15-27.2021}, pages = {15 -- 27}, year = {2021}, abstract = {The presented paper gives an overview of the most important and most common theories and concepts from the economic field of organisational change and is also enriched with quantitative publication data, which underlines the relevance of the topic. In particular, the topic presented is interwoven in an interdisciplinary way with economic psychological models, which are underpinned within the models with content from leading scholars in the field. The pace of change in companies is accelerating, as is technological change in our society. Adaptations of the corporate structure, but also of management techniques and tasks, are therefore indispensable. This includes not only the right approaches to employee motivation, but also the correct use of intrinsic and extrinsic motivational factors. Based on the hypothesis put forward by the scientist and researcher Rollinson in his book "Organisational behaviour and analysis" that managers believe motivational resources are available at all times, socio-economic and economic psychological theories are contrasted here in order to critically examine this statement. In addition, a fictitious company was created as a model for this work in order to illustrate the effects of motivational deficits in practice. In this context, the theories presented are applied to concrete problems within the model and conclusions are drawn about their influence and applicability. This led to the conclusion that motivation is a very individual challenge for each employee, which requires adapted and personalised approaches. On the other hand, the recommendations for action for supervisors in the case of motivation deficits also cannot be answered in a blanket manner, but can only be solved with the help of professional, expert-supported processing due to the economic-psychological realities of motivation. Identifying, analysing and remedying individual employee motivation deficits is, according to the authors, a problem and a challenge of great importance, especially in the context of rapidly changing ecosystems in modern companies, as motivation also influences other factors such as individual productivity. The authors therefore conclude that good motivation through the individual and customised promotion and further training of employees is an important point for achieving important corporate goals in order to remain competitive on the one hand and to create a productive and pleasant working environment on the other.}, language = {en} } @article{HerssensCowburnAlbrachtetal.2022, author = {Herssens, Nolan and Cowburn, James and Albracht, Kirsten and Braunstein, Bjoern and Cazzola, Dario and Colyer, Steffi and Minetti, Alberto E. and Pavei, Gaspare and Rittweger, J{\"o}rn and Weber, Tobias and Green, David A.}, title = {Movement in low gravity environments (MoLo) programme - the MoLo-L.O.O.P. study protocol}, series = {PLOS ONE / Public Library of Science}, volume = {17}, journal = {PLOS ONE / Public Library of Science}, number = {11}, editor = {Cattaneo, Luigi}, publisher = {Plos}, address = {San Francisco}, issn = {1932-6203}, doi = {10.1371/journal.pone.0278051}, pages = {e0278051}, year = {2022}, abstract = {Exposure to prolonged periods in microgravity is associated with deconditioning of the musculoskeletal system due to chronic changes in mechanical stimulation. Given astronauts will operate on the Lunar surface for extended periods of time, it is critical to quantify both external (e.g., ground reaction forces) and internal (e.g., joint reaction forces) loads of relevant movements performed during Lunar missions. Such knowledge is key to predict musculoskeletal deconditioning and determine appropriate exercise countermeasures associated with extended exposure to hypogravity.}, language = {en} } @incollection{RebelHueningScholletal.2015, author = {Rebel, S{\"o}ren and H{\"u}ning, Felix and Scholl, Ingrid and Ferrein, Alexander}, title = {MQOne: Low-cost design for a rugged-terrain robot platform}, series = {Intelligent robotics and applications : 8th International Conference, ICIRA 2015, Portsmouth, UK, August 24-27, 2015, Proceedings, Part II (Lecture notes in computer science : vol. 9245)}, booktitle = {Intelligent robotics and applications : 8th International Conference, ICIRA 2015, Portsmouth, UK, August 24-27, 2015, Proceedings, Part II (Lecture notes in computer science : vol. 9245)}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-22875-4 (print) ; 978-3-319-22876-1 (E-Book)}, doi = {10.1007/978-3-319-22876-1_19}, pages = {209 -- 221}, year = {2015}, abstract = {Rugged terrain robot designs are important for field robotics missions. A number of commercial platforms are available, however, at an impressive price. In this paper, we describe the hardware and software component of a low-cost wheeled rugged-terrain robot. The robot is based on an electric children quad bike and is modified to be driven by wire. In terms of climbing properties, operation time and payload it can compete with some of the commercially available platforms, but at a far lower price.}, language = {en} } @article{KraffWredeSchoembergetal.2013, author = {Kraff, Oliver and Wrede, Karsten H. and Schoemberg, Tobias and Dammann, Philipp and Noureddine, Yacine and Orzada, Stephan and Ladd, Mark E. and Bitz, Andreas}, title = {MR safety assessment of potential RF heating from cranial fixation plates at 7 T}, series = {Medical Physics}, volume = {40}, journal = {Medical Physics}, number = {4}, publisher = {Wiley}, address = {Hoboken}, issn = {2473-4209}, doi = {10.1118/1.4795347}, pages = {042302-1 -- 042302-10}, year = {2013}, language = {en} } @incollection{MuellerVeggianKopsQuinetal.2007, author = {M{\"u}ller-Veggian, Mattea and Kops, Elena Rota and Quin, Peng and Herzog, Hans}, title = {MRI Based Attenuation Correction for Brain PET Images}, series = {Advances in medical engineering / [3rd RPT - Remagener Physiktage together with the Second Scientific Workshop of Medical Robotics, Navigation and Visualization ... Remagen ... 7.-9. M{\"a}rz 2007]. Thorsten M. Buzug (ed.) Part 1.}, booktitle = {Advances in medical engineering / [3rd RPT - Remagener Physiktage together with the Second Scientific Workshop of Medical Robotics, Navigation and Visualization ... Remagen ... 7.-9. M{\"a}rz 2007]. Thorsten M. Buzug (ed.) Part 1.}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-540-68763-4}, doi = {10.1007/978-3-540-68764-1_15}, pages = {93 -- 97}, year = {2007}, abstract = {This work describes a procedure to yield attenuation maps from MR images which are used for the absorption correction (AC) of brain PET data. Such an approach could be mandatory for future combined PET and MRI scanners, which probably do not include a transmission facility. T1-weighted MR images were segmented into brain tissue, bone, soft tissue, and sinus; attenuation coefficients corresponding to elemental composition and density as well as to 511 keV photon energy were respectively assigned. Attenuation maps containing up to four compartments were created and forward projected into sinograms with attenuation factors which then were used for AC during reconstruction of FDG-PET data. The commonly used AC based on a radioactive (68Ge) transmission scan served as reference. The reconstructed radioactivity values obtained with the MRI-based AC were about 20\% lower than those obtained with PET-based AC if the skull was not taken into account. Considering the skull the difference was still about 10\%. Our investigations demonstrate the feasibility of a MRI-based AC, but revealed also the necessity of a satisfying delineation of bone thickness which tends to be underestimated in our first approach of T1-weighted MR image segmentation.}, language = {en} } @inproceedings{BuxbaumSchwarteRingbecketal.2002, author = {Buxbaum, Bernd and Schwarte, Rudolf and Ringbeck, Thorsten and Grothof, Markus and Luan, Xuming}, title = {MSM-PMD as correlation receiver in a new 3D-ranging system}, series = {Laser radar ranging and atmospheric lidar techniques III : 17 - 18 September 2001, Toulouse, France. - (SPIE proceedings series ; 4546)}, booktitle = {Laser radar ranging and atmospheric lidar techniques III : 17 - 18 September 2001, Toulouse, France. - (SPIE proceedings series ; 4546)}, editor = {Schreiber, Ulrich}, publisher = {SPIE}, address = {Bellingham, Wash.}, isbn = {0-8194-4271-2}, issn = {0038-7355}, doi = {10.1117/12.453994}, pages = {145 -- 154}, year = {2002}, language = {en} } @article{Mertens1998, author = {Mertens, Josef}, title = {Multi point design challenges for supersonic transports}, series = {Fluid dynamics research on supersonic aircraft : this report is a compilation of the edited proceedings of the special course on "Fluid dynamics research on supersonic aircraft" held at the Karman Institute for Fluid Dynamics (VKI) in Rhode-Saint-Genese, Belgium, 25-29 May 1998}, journal = {Fluid dynamics research on supersonic aircraft : this report is a compilation of the edited proceedings of the special course on "Fluid dynamics research on supersonic aircraft" held at the Karman Institute for Fluid Dynamics (VKI) in Rhode-Saint-Genese, Belgium, 25-29 May 1998}, publisher = {Research and Technology Organization}, address = {Neuilly-sur-Seine}, isbn = {92-837-1007-X}, pages = {8.1 -- 8.12}, year = {1998}, language = {en} } @inproceedings{KloeserKohlKraftetal.2021, author = {Kl{\"o}ser, Lars and Kohl, Philipp and Kraft, Bodo and Z{\"u}ndorf, Albert}, title = {Multi-attribute relation extraction (MARE): simplifying the application of relation extraction}, series = {Proceedings of the 2nd International Conference on Deep Learning Theory and Applications DeLTA - Volume 1}, booktitle = {Proceedings of the 2nd International Conference on Deep Learning Theory and Applications DeLTA - Volume 1}, publisher = {SciTePress}, address = {Set{\´u}bal}, isbn = {978-989-758-526-5}, doi = {10.5220/0010559201480156}, pages = {148 -- 156}, year = {2021}, abstract = {Natural language understanding's relation extraction makes innovative and encouraging novel business concepts possible and facilitates new digitilized decision-making processes. Current approaches allow the extraction of relations with a fixed number of entities as attributes. Extracting relations with an arbitrary amount of attributes requires complex systems and costly relation-trigger annotations to assist these systems. We introduce multi-attribute relation extraction (MARE) as an assumption-less problem formulation with two approaches, facilitating an explicit mapping from business use cases to the data annotations. Avoiding elaborated annotation constraints simplifies the application of relation extraction approaches. The evaluation compares our models to current state-of-the-art event extraction and binary relation extraction methods. Our approaches show improvement compared to these on the extraction of general multi-attribute relations.}, language = {en} } @article{YoshinobuErmelenkoMourzinaetal.2003, author = {Yoshinobu, T. and Ermelenko, Y. and Mourzina, Y. and Sch{\"o}ning, Michael Josef and Iwasaki, H. and Vlasov, Y.}, title = {Multi-component analysis based on the light-addressable potentiometric sensor (LAPS)}, series = {Proceedings : 11th international conference Sensor 2003; 13 - 15 May 2003, Exhibition Centre Nuremberg, Germany}, journal = {Proceedings : 11th international conference Sensor 2003; 13 - 15 May 2003, Exhibition Centre Nuremberg, Germany}, publisher = {AMA Service}, address = {Wunstorf}, pages = {141 -- 144}, year = {2003}, language = {en} } @inproceedings{MuellerAltherrAholaetal.2019, author = {M{\"u}ller, Tim M. and Altherr, Lena and Ahola, Marja and Schabel, Samuel and Pelz, Peter F.}, title = {Multi-Criteria optimization of pressure screen systems in paper recycling - balancing quality, yield, energy consumption and system complexity}, series = {EngOpt 2018 Proceedings of the 6th International Conference on Engineering Optimization}, booktitle = {EngOpt 2018 Proceedings of the 6th International Conference on Engineering Optimization}, editor = {Rodrigues, H. C.}, publisher = {Springer International Publishing}, address = {Basel}, isbn = {978-3-319-97773-7}, doi = {10.1007/978-3-319-97773-7_105}, year = {2019}, abstract = {The paper industry is the industry with the third highest energy consumption in the European Union. Using recycled paper instead of fresh fibers for papermaking is less energy consuming and saves resources. However, adhesive contaminants in recycled paper are particularly problematic since they reduce the quality of the resulting paper-product. To remove as many contaminants and at the same time obtain as many valuable fibres as possible, fine screening systems, consisting of multiple interconnected pressure screens, are used. Choosing the best configuration is a non-trivial task: The screens can be interconnected in several ways, and suitable screen designs as well as operational parameters have to be selected. Additionally, one has to face conflicting objectives. In this paper, we present an approach for the multi-criteria optimization of pressure screen systems based on Mixed-Integer Nonlinear Programming. We specifically focus on a clear representation of the trade-off between different objectives.}, language = {en} } @inproceedings{RajanKubalskiAltayetal.2017, author = {Rajan, Sreelakshmy and Kubalski, Thomas and Altay, Okyay and Dalguer, Luis A and Butenweg, Christoph}, title = {Multi-dimensional fragility analysis of a RC building with components using response surface method}, series = {24th International Conference on Structural Mechanics in Reactor Technology, Busan, Korea, 20-25 August, 2017}, booktitle = {24th International Conference on Structural Mechanics in Reactor Technology, Busan, Korea, 20-25 August, 2017}, publisher = {International Assn for Structural Mechanics in Reactor Technology (IASMiRT)}, address = {Raleigh, USA}, isbn = {9781510856776}, pages = {3126 -- 3135}, year = {2017}, abstract = {Conventional fragility curves describe the vulnerability of the main structure under external hazards. However, in complex structures such as nuclear power plants, the safety or the risk depends also on the components associated with a system. The classical fault tree analysis gives an overall view of the failure and contains several subsystems to the main event, however, the interactions in the subsystems are not well represented. In order to represent the interaction of the components, a method suggested by Cimellaro et al. (2006) using multidimensional performance limit state functions to obtain the system fragility curves is adopted. This approach gives the possibility of deriving the cumulative fragility taking into account the interaction of the response of different components. In this paper, this approach is used to evaluate seismic risk of a representative electrical building infrastructure, including the component, of a nuclear power plant. A simplified model of the structure, with nonlinear material behavior is employed for the analysis in Abaqus©. The input variables considered are the material parameters, boundary conditions and the seismic input. The variability of the seismic input is obtained from selected ground motion time histories of spectrum compatible synthetic ccelerograms. Unlike the usual Monte Carlo methods used for the probabilistic analysis of the structure, a computationally effective response surface method is used. This method reduces the computational effort of the calculations by reducing the required number of samples.}, language = {en} } @inproceedings{BukhariYang2006, author = {Bukhari, Syed Faisal Ahmed and Yang, Wuqiang}, title = {Multi-interface level sensors and new development in monitoring and control of oil separators}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:a96-opus-1498}, year = {2006}, abstract = {In the oil industry, huge saving may be made if suitable multi-interface level measurement systems are employed for effectively monitoring crude oil separators and efficient control of their operation. A number of techniques, e.g. externally mounted displacers, differential pressure transmitters and capacitance rod devices, have been developed to measure the separation process with gas, oil, water and other components. Because of the unavailability of suitable multi-interface level measurement systems, oil separators are currently operated by the trial-and-error approach. In this paper some conventional techniques, which have been used for level measurement in industry, and new development are discussed.}, subject = {Biosensor}, language = {en} } @article{GoettscheAlexopoulosDuemmleretal.2019, author = {G{\"o}ttsche, Joachim and Alexopoulos, Spiros and D{\"u}mmler, Andreas and Maddineni, S. K.}, title = {Multi-Mirror Array Calculations With Optical Error}, pages = {1 -- 6}, year = {2019}, abstract = {The optical performance of a 2-axis solar concentrator was simulated with the COMSOL Multiphysics® software. The concentrator consists of a mirror array, which was created using the application builder. The mirror facets are preconfigured to form a focal point. During tracking all mirrors are moved simultaneously in a coupled mode by 2 motors in two axes, in order to keep the system in focus with the moving sun. Optical errors on each reflecting surface were implemented in combination with the solar angular cone of ± 4.65 mrad. As a result, the intercept factor of solar radiation that is available to the receiver was calculated as a function of the transversal and longitudinal angles of incidence. In addition, the intensity distribution on the receiver plane was calculated as a function of the incidence angles.}, language = {en} } @inproceedings{HuckPoghossianBuniatyanetal.2014, author = {Huck, Christina and Poghossian, Arshak and Buniatyan, V. and Sch{\"o}ning, Michael Josef}, title = {Multi-parameter detection for supporting monitoring and control of biogas processes in agriculture}, series = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)}, booktitle = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)}, publisher = {VDE-Verl.}, address = {Berlin}, organization = {VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik}, isbn = {978-3-8007-3622-5}, pages = {1 -- 5}, year = {2014}, language = {en} } @article{PoghossianSchultzeSchoening2003, author = {Poghossian, Arshak and Schultze, J. W. and Sch{\"o}ning, Michael Josef}, title = {Multi-parameter detection of (bio-)chemical and physical quantities using an identical transducer principle}, series = {Sensors and Actuators B. 91 (2003), H. 1-3}, journal = {Sensors and Actuators B. 91 (2003), H. 1-3}, isbn = {0925-4005}, pages = {83 -- 91}, year = {2003}, language = {en} } @inproceedings{NaetherPoghossianPlatenetal.2006, author = {N{\"a}ther, Niko and Poghossian, Arshak and Platen, J. and Yoshinobu, T. and Koudelka-Hep, M. and Sch{\"o}ning, Michael Josef}, title = {Multi-parameter sensing of both physical and (bio-)chemical quantities using the same transducer principle}, series = {Biochemical sensing utilisation of micro- and nanotechnologies : Warsaw, [23rd - 26th] November 2005 / ed. by M. Mascini ...}, booktitle = {Biochemical sensing utilisation of micro- and nanotechnologies : Warsaw, [23rd - 26th] November 2005 / ed. by M. Mascini ...}, address = {Warsaw}, pages = {172 -- 181}, year = {2006}, language = {en} } @article{HuckPoghossianBaeckeretal.2015, author = {Huck, Christina and Poghossian, Arshak and B{\"a}cker, Matthias and Reisert, Steffen and Kramer, Friederike and Begoyan, Vardges K. and Buniatyan, Vahe V. and Sch{\"o}ning, Michael Josef}, title = {Multi-parameter sensing using high-k oxide of barium strontium titanate}, series = {Physica status solidi (a)}, volume = {212}, journal = {Physica status solidi (a)}, number = {6}, publisher = {Wiley}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201431911}, pages = {1259}, year = {2015}, abstract = {High-k perovskite oxide of barium strontium titanate (BST) represents a very attractive multi-functional transducer material for the development of (bio-)chemical sensors. In this work, a Si-based sensor chip containing Pt interdigitated electrodes covered with a thin BST layer (485 nm) has been developed for multi-parameter chemical sensing. The chip has been applied for the contactless measurement of the electrolyte conductivity, the detection of adsorbed charged macromolecules (positively charged polyelectrolytes of polyethylenimine) and the concentration of hydrogen peroxide (H2O2) vapor. The experimental results of functional testing of individual sensors are presented. The mechanism of the BST sensitivity to charged polyelectrolytes and H2O2 vapor has been proposed and discussed.}, language = {en} } @inproceedings{SchmidtsBoltesKraftetal.2017, author = {Schmidts, Oliver and Boltes, Maik and Kraft, Bodo and Schreiber, Marc}, title = {Multi-pedestrian tracking by moving Bluetooth-LE beacons and stationary receivers}, series = {2017 International Conference on Indoor Positioning and Indoor Navigation (IPIN), 18-21 September 2017, Sapporo, Japan}, booktitle = {2017 International Conference on Indoor Positioning and Indoor Navigation (IPIN), 18-21 September 2017, Sapporo, Japan}, pages = {1 -- 4}, year = {2017}, language = {en} } @article{ReisertSchneiderGeissleretal.2013, author = {Reisert, Steffen and Schneider, Benno and Geissler, Hanno and Gompel, Matthias van and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Multi-sensor chip for the investigation of different types of metal oxides for the detection of H2O2 in the ppm range}, series = {physica status solidi (a)}, volume = {210}, journal = {physica status solidi (a)}, number = {5}, publisher = {Wiley}, address = {Weinheim}, issn = {1862-6319}, pages = {898 -- 904}, year = {2013}, abstract = {In this work, a multi-sensor chip for the investigation of the sensing properties of different types of metal oxides towards hydrogen peroxide in the ppm range is presented. The fabrication process and physical characterization of the multi-sensor chip are described. Pure SnO2 and WO3 as well as Pd- and Pt-doped SnO2 films are characterized in terms of their sensitivity to H2O2. The sensing films have been prepared by drop-coating of water-dispensed nano-powders. A physical characterization, including scanning electron microscopy and X-ray diffraction analysis of the deposited metal-oxide films, was done. From the measurements in hydrogen peroxide atmosphere, it could be shown, that all of the tested metal oxide films are suitable for the detection of H2O2 in the ppm range. The highest sensitivity and reproducibility was achieved using Pt-doped SnO2. Calibration plot of a SnO2, WO3, Pt-, and Pd-doped SnO2 gas sensor for H2O2 concentrations in the ppm range.}, language = {en} } @inproceedings{FeldhusenBrezingPuetzetal.2010, author = {Feldhusen, J{\"o}rg and Brezing, Alexander Nikolaus and P{\"u}tz, Claus and W{\"a}hlisch, Georg}, title = {Multi-system CAD-teaching in large classes}, series = {When design education and design research meet : proceedings of the 12th International Conference on Engineering and Product Design Education, Norwegian University of Science and Technology (NTNU) Trondheim, Norway, 2nd - 3rd September 2010 ; [E\&PDE]}, booktitle = {When design education and design research meet : proceedings of the 12th International Conference on Engineering and Product Design Education, Norwegian University of Science and Technology (NTNU) Trondheim, Norway, 2nd - 3rd September 2010 ; [E\&PDE]}, publisher = {Design Society}, address = {Glasgow}, organization = {International Conference on Engineering and Product Design Education <12, 2010, Trondheim>}, isbn = {978-1-904670-19-3}, pages = {204 -- 209}, year = {2010}, language = {en} } @article{MiyamotoWagnerSchoeningetal.2011, author = {Miyamoto, K. and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, T.}, title = {Multi-well structure for cell culture on the chemical imaging sensor}, publisher = {IEEE}, address = {New York}, pages = {2130 -- 2132}, year = {2011}, language = {en} } @article{AdelsElbersDiehletal.2023, author = {Adels, Klaudia and Elbers, Gereon and Diehl, Bernd and Monakhova, Yulia}, title = {Multicomponent analysis of dietary supplements containing glucosamine and chondroitin: comparative low- and high-field NMR spectroscopic study}, series = {Analytical Sciences}, volume = {2023}, journal = {Analytical Sciences}, publisher = {Springer Verlag}, address = {Cham}, issn = {1348-2246 (Online)}, doi = {10.1007/s44211-023-00433-2}, pages = {13 Seiten}, year = {2023}, abstract = {With the prevalence of glucosamine- and chondroitin-containing dietary supplements for people with osteoarthritis in the marketplace, it is important to have an accurate and reproducible analytical method for the quantitation of these compounds in finished products. NMR spectroscopic method based both on low- (80 MHz) and high- (500-600 MHz) field NMR instrumentation was established, compared and validated for the determination of chondroitin sulfate and glucosamine in dietary supplements. The proposed method was applied for analysis of 20 different dietary supplements. In the majority of cases, quantification results obtained on the low-field NMR spectrometer are similar to those obtained with high-field 500-600 MHz NMR devices. Validation results in terms of accuracy, precision, reproducibility, limit of detection and recovery demonstrated that the developed method is fit for purpose for the marketed products. The NMR method was extended to the analysis of methylsulfonylmethane, adulterant maltodextrin, acetate and inorganic ions. Low-field NMR can be a quicker and cheaper alternative to more expensive high-field NMR measurements for quality control of the investigated dietary supplements. High-field NMR instrumentation can be more favorable for samples with complex composition due to better resolution, simultaneously giving the possibility of analysis of inorganic species such as potassium and chloride.}, language = {en} } @article{SchubertSchoeningMourzinaetal.2001, author = {Schubert, J. and Sch{\"o}ning, Michael Josef and Mourzina, Y. G. and Legin, A. V. and Vlasov, Y. G. and Zander, W. and L{\"u}th, H.}, title = {Multicomponent thin films for electrochemical sensor applications prepared by pulsed laser deposition}, series = {Sensors and Actuators B. 76 (2001), H. 1-3}, journal = {Sensors and Actuators B. 76 (2001), H. 1-3}, isbn = {0925-4005}, pages = {327 -- 330}, year = {2001}, language = {en} } @article{JacobsQuernheim1990, author = {Jacobs, Stephan and Quernheim, Ulrich}, title = {Multicopy ARQ Error Control Techniques for Multipoint Satellite Links / Ulrich Quernheim, Stephan Jacobs}, series = {Proceedings of the IFIP TC 6 International Conference on Information Network and Data Communication : Lillehammer, Norway, 26 - 29 March, 1990 / ed. by Dipak Khakhar ...}, journal = {Proceedings of the IFIP TC 6 International Conference on Information Network and Data Communication : Lillehammer, Norway, 26 - 29 March, 1990 / ed. by Dipak Khakhar ...}, publisher = {North-Holland}, address = {Amsterdam [u.a.]}, isbn = {0-444-88696-6}, pages = {XI, 411 S. : Ill., graph. Darst.}, year = {1990}, language = {en} } @inproceedings{AltherrEdererFarnetaneetal.2017, author = {Altherr, Lena and Ederer, Thorsten and Farnetane, Lucas S. and P{\"o}ttgen, Philipp and Verg{\´e}, Angela and Pelz, Peter F.}, title = {Multicriterial design of a hydrostatic transmission system via mixed-integer programming}, series = {Operations Research Proceedings 2015}, booktitle = {Operations Research Proceedings 2015}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-42901-4}, doi = {10.1007/978-3-319-42902-1_41}, pages = {301 -- 307}, year = {2017}, abstract = {In times of planned obsolescence the demand for sustainability keeps growing. Ideally, a technical system is highly reliable, without failures and down times due to fast wear of single components. At the same time, maintenance should preferably be limited to pre-defined time intervals. Dispersion of load between multiple components can increase a system's reliability and thus its availability inbetween maintenance points. However, this also results in higher investment costs and additional efforts due to higher complexity. Given a specific load profile and resulting wear of components, it is often unclear which system structure is the optimal one. Technical Operations Research (TOR) finds an optimal structure balancing availability and effort. We present our approach by designing a hydrostatic transmission system.}, language = {en} } @article{AltherrEdererPoettgenetal.2015, author = {Altherr, Lena and Ederer, Thorsten and P{\"o}ttgen, Philipp and Lorenz, Ulf and Pelz, Peter F.}, title = {Multicriterial optimization of technical systems considering multiple load and availability scenarios}, series = {Applied Mechanics and Materials}, volume = {807}, journal = {Applied Mechanics and Materials}, editor = {Pelz, Peter F. and Groche, Peter}, isbn = {1660-9336}, doi = {10.4028/www.scientific.net/AMM.807.247}, pages = {247 -- 256}, year = {2015}, abstract = {Cheap does not imply cost-effective -- this is rule number one of zeitgeisty system design. The initial investment accounts only for a small portion of the lifecycle costs of a technical system. In fluid systems, about ninety percent of the total costs are caused by other factors like power consumption and maintenance. With modern optimization methods, it is already possible to plan an optimal technical system considering multiple objectives. In this paper, we focus on an often neglected contribution to the lifecycle costs: downtime costs due to spontaneous failures. Consequently, availability becomes an issue.}, language = {en} } @article{HartungDondetiCastleford2007, author = {Hartung, Frank and Dondeti, L. and Castleford, F.}, title = {Multimedia Internet KEYing (MIKEY) General Extension Payload for Open Mobile Alliance BCAST LTKM/STKM Transport / Dondeti, L. ; Castleford, D. ; Hartung, F.}, pages = {1 -- 7}, year = {2007}, language = {en} } @article{SawadaNakazawaTakenagaetal.2014, author = {Sawada, Kazuaki and Nakazawa, Hirokazu and Takenaga, Shoko and Hizawa, Takeshi and Futagawa, Masato and Dasai, Fumihiro and Sakurai, Takashi and Okumura, Koichi and Hattori, Toshiaki and Ishida, Makoto}, title = {Multimodal bioimage sensor}, series = {IEICE transactions on fundamentals of electronics, communidations and computer sciences}, volume = {E97-A (2014)}, journal = {IEICE transactions on fundamentals of electronics, communidations and computer sciences}, number = {3}, publisher = {IEICE}, address = {Tokyo}, issn = {0916-8508 (Print) ; 1745-1337 (Online)}, doi = {10.1587/transfun.E97.A.726}, pages = {726 -- 733}, year = {2014}, abstract = {To visualize the biochemical distribution two-dimensionally, we invented a solid-state-type ion image sensor that indicates the chemical activity of solutions and cells. The device, which consists of a CCD array covered with a functionalized membrane to detect charge accumulation, is highly sensitive to changes in the concentration and two-dimensional distribution of ions and biomaterials.}, language = {en} } @article{MonakhovaDiehl2022, author = {Monakhova, Yulia and Diehl, Bernd W.K.}, title = {Multinuclear NMR screening of pharmaceuticals using standardization by 2H integral of a deuterated solvent}, series = {Journal of Pharmaceutical and Biomedical Analysis}, volume = {209}, journal = {Journal of Pharmaceutical and Biomedical Analysis}, number = {Article number: 114530}, publisher = {Elsevier}, isbn = {0731-7085}, doi = {10.1016/j.jpba.2021.114530}, year = {2022}, abstract = {NMR standardization approach that uses the 2H integral of deuterated solvent for quantitative multinuclear analysis of pharmaceuticals is described. As a proof of principle, the existing NMR procedure for the analysis of heparin products according to US Pharmacopeia monograph is extended to the determination of Na+ and Cl- content in this matrix. Quantification is performed based on the ratio of a 23Na (35Cl) NMR integral and 2H NMR signal of deuterated solvent, D2O, acquired using the specific spectrometer hardware. As an alternative, the possibility of 133Cs standardization using the addition of Cs2CO3 stock solution is shown. Validation characteristics (linearity, repeatability, sensitivity) are evaluated. A holistic NMR profiling of heparin products can now also be used for the quantitative determination of inorganic compounds in a single analytical run using a single sample. In general, the new standardization methodology provides an appealing alternative for the NMR screening of inorganic and organic components in pharmaceutical products.}, language = {en} } @article{PrielmeierLang1988, author = {Prielmeier, Franz and Lang, E. W.}, title = {Multinuclear Spin-Lattice Relaxation Time Studies of Supercooled Aqueous LiCl-Solutions / E .W. Lang, F. X. Prielmeier}, series = {Berichte der Bunsen-Gesellschaft f{\"u}r Physikalische Chemie. 92 (1988)}, journal = {Berichte der Bunsen-Gesellschaft f{\"u}r Physikalische Chemie. 92 (1988)}, isbn = {0005-9021}, pages = {717}, year = {1988}, language = {en} } @article{Pieper2011, author = {Pieper, Martin}, title = {Multiobjective optimization with expensive objectives applied to a thermodynamic material design problem}, series = {Proceedings in applied mathematics and mechanics : PAMM. 11 (2011), H. 1}, journal = {Proceedings in applied mathematics and mechanics : PAMM. 11 (2011), H. 1}, publisher = {Wiley}, address = {Weinheim}, isbn = {1617-7061}, pages = {733 -- 734}, year = {2011}, language = {en} } @article{HuckPoghossianKerroumietal.2014, author = {Huck, Christina and Poghossian, Arshak and Kerroumi, Iman and Schusser, Sebastian and B{\"a}cker, Matthias and Zander, Willi and Schubert, J{\"u}rgen and Buniatyan, Vahe V. and Martirosyan, Norayr W. and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Multiparameter sensor chip with Barium Strontium Titanate as multipurpose material}, series = {Electroanalysis}, volume = {26}, journal = {Electroanalysis}, number = {5}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1521-4109 (E-Journal); 1040-0397 (Print)}, doi = {10.1002/elan.201400076}, pages = {980 -- 987}, year = {2014}, abstract = {It is well known that biochemical and biotechnological processes are strongly dependent and affected by a variety of physico-chemical parameters such as pH value, temperature, pressure and electrolyte conductivity. Therefore, these quantities have to be monitored or controlled in order to guarantee a stable process operation, optimization and high yield. In this work, a sensor chip for the multiparameter detection of three physico-chemical parameters such as electrolyte conductivity, pH and temperature is realized using barium strontium titanate (BST) as multipurpose material. The chip integrates a capacitively coupled four-electrode electrolyte-conductivity sensor, a capacitive field-effect pH sensor and a thin-film Pt-temperature sensor. Due to the multifunctional properties of BST, it is utilized as final outermost coating layer of the processed sensor chip and serves as passivation and protection layer as well as pH-sensitive transducer material at the same time. The results of testing of the individual sensors of the developed multiparameter sensor chip are presented. In addition, a quasi-simultaneous multiparameter characterization of the sensor chip in buffer solutions with different pH value and electrolyte conductivity is performed. To study the sensor behavior and the suitability of BST as multifunctional material under harsh environmental conditions, the sensor chip was exemplarily tested in a biogas digestate.}, language = {en} } @inproceedings{SchoppHeuermannMarso2017, author = {Schopp, Christoph and Heuermann, Holger and Marso, Michel}, title = {Multiphysical Study of an Atmospheric Microwave Argon Plasma Jet}, series = {IEEE Transactions on Plasma Science}, volume = {45}, booktitle = {IEEE Transactions on Plasma Science}, number = {6}, publisher = {IEEE}, issn = {1939-9375}, doi = {10.1109/TPS.2017.2692735}, pages = {932 -- 937}, year = {2017}, language = {en} } @article{Tran2014, author = {Tran, Duc Hung}, title = {Multiple corporate governance attributes and the cost of capital - Evidence from Germany}, series = {The British Accounting Review}, volume = {46}, journal = {The British Accounting Review}, number = {2}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0890-8389}, doi = {https://doi.org/10.1016/j.bar.2014.02.003}, pages = {179 -- 197}, year = {2014}, abstract = {This paper investigates the extent to which corporate governance affects the cost of debt and equity capital of German exchange-listed companies. I examine corporate governance along three dimensions: financial information quality, ownership structure and board structure. The results suggest that firms with high levels of financial transparency and bonus compensations face lower cost of equity. In addition, block ownership is negatively related to firms' cost of equity when the blockholders are other firms, managers or founding-family members. Consistent with the conjecture that agency costs increase with firm size, I find significant cost of debt effects only in the largest German companies. Here, the creditors demand lower cost of debt from firms with block ownerships held by corporations or banks. My findings demonstrate that a uniform set of governance attributes is unlikely to satisfy suppliers of debt and equity capital equally.}, language = {en} } @inproceedings{PfaffVinsonneauBurnham2006, author = {Pfaff, Raphael and Vinsonneau, B. and Burnham, K. J.}, title = {Multiple models for nonlinear systems}, series = {Proceedings / Eigteenth International Conference on Systems Engineering : ICSE 2006 : 5 - 7 September 2006 ; [held at Coventry University, UK]}, booktitle = {Proceedings / Eigteenth International Conference on Systems Engineering : ICSE 2006 : 5 - 7 September 2006 ; [held at Coventry University, UK]}, organization = {International Conference on Systems Engineering <18, 2006, Coventry>}, isbn = {1-84600-013-0}, pages = {347 -- 352}, year = {2006}, language = {en} } @inproceedings{PeloniDachwaldCeriotti2017, author = {Peloni, Alessandro and Dachwald, Bernd and Ceriotti, Matteo}, title = {Multiple NEA rendezvous mission: Solar sailing options}, series = {Fourth International Symposium on Solar Sailing}, booktitle = {Fourth International Symposium on Solar Sailing}, pages = {1 -- 11}, year = {2017}, abstract = {The scientific interest in near-Earth asteroids (NEAs) and the classification of some of those as potentially hazardous asteroid for the Earth stipulated the interest in NEA exploration. Close-up observations of these objects will increase drastically our knowledge about the overall NEA population. For this reason, a multiple NEA rendezvous mission through solar sailing is investigated, taking advantage of the propellantless nature of this groundbreaking propulsion technology. Considering a spacecraft based on the DLR/ESA Gossamer technology, this work focuses on the search of possible sequences of NEA encounters. The effectiveness of this approach is demonstrated through a number of fully-optimized trajectories. The results show that it is possible to visit five NEAs within 10 years with near-term solar-sail technology. Moreover, a study on a reduced NEA database demonstrates the reliability of the approach used, showing that 58\% of the sequences found with an approximated trajectory model can be converted into real solar-sail trajectories. Lastly, this second study shows the effectiveness of the proposed automatic optimization algorithm, which is able to find solutions for a large number of mission scenarios without any input required from the user.}, language = {en} } @article{DachwaldSeboldt2005, author = {Dachwald, Bernd and Seboldt, Wolfgang}, title = {Multiple Near-Earth Asteroid Rendezvous and Sample Return Using First Generation Solar Sailcraft}, series = {Acta Astronautica. 57 (2005), H. 11}, journal = {Acta Astronautica. 57 (2005), H. 11}, isbn = {0094-5765}, pages = {864 -- 875}, year = {2005}, language = {en} } @article{PeloniDachwaldCeriotti2017, author = {Peloni, Alessandro and Dachwald, Bernd and Ceriotti, Matteo}, title = {Multiple near-earth asteroid rendezvous mission: Solar-sailing options}, series = {Advances in Space Research}, journal = {Advances in Space Research}, number = {In Press, Corrected Proof}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0273-1177}, doi = {10.1016/j.asr.2017.10.017}, year = {2017}, language = {en} } @article{DachwaldSeboldtRichter2003, author = {Dachwald, Bernd and Seboldt, Wolfgang and Richter, L.}, title = {Multiple Rendezvous and Sample Return Missions to Near-Earth Asteroids Using Solar Sailcraft}, series = {Proceedings of the Fifth IAA International Conference on Low Cost Planetary Missions : 24 - 26 September 2003, ESTEC, Noordwijk, the Netherlands / [comp. by R. A. Harris]}, journal = {Proceedings of the Fifth IAA International Conference on Low Cost Planetary Missions : 24 - 26 September 2003, ESTEC, Noordwijk, the Netherlands / [comp. by R. A. Harris]}, publisher = {ESA}, address = {Noordwijk}, isbn = {92-9092-853-0}, pages = {351 -- 358}, year = {2003}, language = {en} } @article{DachwaldSeboldtRichter2006, author = {Dachwald, Bernd and Seboldt, Wolfgang and Richter, L.}, title = {Multiple rendezvous and sample return missions to near-Earth objects using solar sailcraft / Dachwald, B. ; Seboldt, W. ; Richter, L.}, series = {Acta Astronautica. 59 (2006), H. 8-11}, journal = {Acta Astronautica. 59 (2006), H. 8-11}, isbn = {0094-5765}, pages = {768 -- 776}, year = {2006}, language = {en} } @article{ReisertGeisslerWeileretal.2015, author = {Reisert, Steffen and Geissler, H. and Weiler, C. and Wagner, P. and Sch{\"o}ning, Michael Josef}, title = {Multiple sensor-type system for monitoring the microbicidal effectiveness of aseptic sterilisation processes}, series = {Food control}, volume = {47}, journal = {Food control}, issn = {1873-7129 (E-Journal); 0956-7135 (Print)}, doi = {10.1016/j.foodcont.2014.07.063}, pages = {615 -- 622}, year = {2015}, abstract = {The present work describes a novel multiple sensor-type system for the real-time analysis of aseptic sterilisation processes employing gaseous hydrogen peroxide (H2O2) as a sterilant. The inactivation kinetics of Bacillus atrophaeus by gaseous H2O2 have been investigated by means of a methodical calibration experiment, taking into account the process variables H2O2 concentration, humidity and gas temperature. It has been found that the microbicidal effectiveness at H2O2 concentrations above 2\% v/v is largely determined by the concentration itself, while at lower H2O2 concentrations, the gas temperature and humidity play a leading role. Furthermore, the responses of different types of gas sensors towards the influencing factors of the sterilisation process have been analysed within the same experiment. Based on a correlation established between the inactivation kinetics and the sensor responses, a calorimetric H2O2 sensor and a metal-oxide semiconductor (MOX) sensor have been identified as possible candidates for monitoring the microbicidal effectiveness of aseptic sterilisation processes employing gaseous H2O2. Therefore, two linear models that describe the relationship between sensor response and microbicidal effectiveness have been proposed.}, language = {en} } @article{AchtsnichtPourshahidiOffenhaeusseretal.2019, author = {Achtsnicht, Stefan and Pourshahidi, Ali Mohammad and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim}, title = {Multiplex detection of different magnetic beads using frequency scanning in magnetic frequency mixing technique}, series = {Sensors}, volume = {19}, journal = {Sensors}, number = {11}, publisher = {MDPI}, address = {Basel}, issn = {1424-8220}, doi = {10.3390/s19112599}, pages = {13 Seiten}, year = {2019}, abstract = {In modern bioanalytical methods, it is often desired to detect several targets in one sample within one measurement. Immunological methods including those that use superparamagnetic beads are an important group of techniques for these applications. The goal of this work is to investigate the feasibility of simultaneously detecting different superparamagnetic beads acting as markers using the magnetic frequency mixing technique. The frequency of the magnetic excitation field is scanned while the lower driving frequency is kept constant. Due to the particles' nonlinear magnetization, mixing frequencies are generated. To record their amplitude and phase information, a direct digitization of the pickup-coil's signal with subsequent Fast Fourier Transformation is performed. By synchronizing both magnetic beads using frequency scanning in magnetic frequency mixing technique magnetic fields, a stable phase information is gained. In this research, it is shown that the amplitude of the dominant mixing component is proportional to the amount of superparamagnetic beads inside a sample. Additionally, it is shown that the phase does not show this behaviour. Excitation frequency scans of different bead types were performed, showing different phases, without correlation to their diverse amplitudes. Two commercially available beads were selected and a determination of their amount in a mixture is performed as a demonstration for multiplex measurements.}, language = {en} } @article{PourshahidiAchtsnichtNambipareecheeetal.2021, author = {Pourshahidi, Ali Mohammad and Achtsnicht, Stefan and Nambipareechee, Mrinal Murali and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim}, title = {Multiplex detection of magnetic beads using offset field dependent frequency mixing magnetic detection}, series = {Sensors}, volume = {21}, journal = {Sensors}, number = {17}, publisher = {MDPI}, address = {Basel}, issn = {1424-8220}, doi = {10.3390/s21175859}, pages = {16 Seiten}, year = {2021}, abstract = {Magnetic immunoassays employing Frequency Mixing Magnetic Detection (FMMD) have recently become increasingly popular for quantitative detection of various analytes. Simultaneous analysis of a sample for two or more targets is desirable in order to reduce the sample amount, save consumables, and save time. We show that different types of magnetic beads can be distinguished according to their frequency mixing response to a two-frequency magnetic excitation at different static magnetic offset fields. We recorded the offset field dependent FMMD response of two different particle types at frequencies ƒ₁ + n⋅ƒ₂, n = 1, 2, 3, 4 with ƒ₁ = 30.8 kHz and ƒ₂ = 63 Hz. Their signals were clearly distinguishable by the locations of the extremes and zeros of their responses. Binary mixtures of the two particle types were prepared with different mixing ratios. The mixture samples were analyzed by determining the best linear combination of the two pure constituents that best resembled the measured signals of the mixtures. Using a quadratic programming algorithm, the mixing ratios could be determined with an accuracy of greater than 14\%. If each particle type is functionalized with a different antibody, multiplex detection of two different analytes becomes feasible.}, language = {en} } @article{KarschuckSchmidtAchtsnichtetal.2023, author = {Karschuck, Tobias and Schmidt, Stefan and Achtsnicht, Stefan and Poghossian, Arshak and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Multiplexing system for automated characterization of a capacitive field-effect sensor array}, series = {Physica Status Solidi A}, volume = {220}, journal = {Physica Status Solidi A}, number = {22}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6300 (Print)}, doi = {10.1002/pssa.202300265}, pages = {7 Seiten}, year = {2023}, abstract = {In comparison to single-analyte devices, multiplexed systems for a multianalyte detection offer a reduced assay time and sample volume, low cost, and high throughput. Herein, a multiplexing platform for an automated quasi-simultaneous characterization of multiple (up to 16) capacitive field-effect sensors by the capacitive-voltage (C-V) and the constant-capacitance (ConCap) mode is presented. The sensors are mounted in a newly designed multicell arrangement with one common reference electrode and are electrically connected to the impedance analyzer via the base station. A Python script for the automated characterization of the sensors executes the user-defined measurement protocol. The developed multiplexing system is tested for pH measurements and the label-free detection of ligand-stabilized, charged gold nanoparticles.}, language = {en} } @article{Heuermann2006, author = {Heuermann, Holger}, title = {Multiport S-parameter calculation from two-port network analyzer measurements with or without switch matrix}, series = {ARFTG Conference, 2006 67th, San Francisco, CA}, journal = {ARFTG Conference, 2006 67th, San Francisco, CA}, isbn = {978-0-7803-9529-9}, pages = {219 -- 222}, year = {2006}, language = {en} } @article{SvaneborgKarimiVarzanehHojdisetal.2016, author = {Svaneborg, Carsten and Karimi-Varzaneh, Hossein Ali and Hojdis, Nils and Fleck, Franz and Everaers, Ralf}, title = {Multiscale approach to equilibrating model polymer melts}, series = {Physical Review E}, volume = {94}, journal = {Physical Review E}, number = {032502}, publisher = {AIP Publishing}, address = {Melville, NY}, issn = {2470-0053}, doi = {10.1103/PhysRevE.94.032502}, year = {2016}, abstract = {We present an effective and simple multiscale method for equilibrating Kremer Grest model polymer melts of varying stiffness. In our approach, we progressively equilibrate the melt structure above the tube scale, inside the tube and finally at the monomeric scale. We make use of models designed to be computationally effective at each scale. Density fluctuations in the melt structure above the tube scale are minimized through a Monte Carlo simulated annealing of a lattice polymer model. Subsequently the melt structure below the tube scale is equilibrated via the Rouse dynamics of a force-capped Kremer-Grest model that allows chains to partially interpenetrate. Finally the Kremer-Grest force field is introduced to freeze the topological state and enforce correct monomer packing. We generate 15 melts of 500 chains of 10.000 beads for varying chain stiffness as well as a number of melts with 1.000 chains of 15.000 monomers. To validate the equilibration process we study the time evolution of bulk, collective, and single-chain observables at the monomeric, mesoscopic, and macroscopic length scales. Extension of the present method to longer, branched, or polydisperse chains, and/or larger system sizes is straightforward.}, language = {en} } @book{Grotendorst2009, author = {Grotendorst, Johannes}, title = {Multiscale Simulation Methods in Molecular Sciences : Institute for Advanced Simulation (IAS) ; winter school, 2 - 6 March 2009, Forschungszentrum J{\"u}lich, Germany ; lecture notes}, address = {J{\"u}lich}, isbn = {978-3-9810843-8-2}, pages = {576 S. : graph. Darst.}, year = {2009}, language = {en} } @article{KhaydukovaZadorozhnayaKirsanovetal.2014, author = {Khaydukova, M. M. and Zadorozhnaya, O. A. and Kirsanov, D. O. and Iken, Heiko and Rolka, David and Sch{\"o}ning, Michael Josef and Babain, V. A. and Vlasov, Yu. G. and Legin, A. V.}, title = {Multivariate processing of atomic-force microscopy images for detection of the response of plasticized polymeric membranes}, series = {Russian journal of applied chemistry}, volume = {87}, journal = {Russian journal of applied chemistry}, number = {3}, publisher = {Springer}, address = {Dordrecht}, issn = {1608-3296 (E-Journal); 1070-4272 (Print)}, doi = {10.1134/S1070427214030112}, pages = {307 -- 314}, year = {2014}, abstract = {The possibility of using the atomic-force microscopy as a method for detection of the analytical signal from plasticized polymeric sensor membranes was analyzed. The surfaces of cadmium-selective membranes based on two polymeric matrices were examined. The digital images were processed with multivariate image analysis techniques. A correlation was found between the surface profile of an ion-selective membrane and the concentration of the ion in solution.}, language = {en} } @article{Ziemons1992, author = {Ziemons, Karl}, title = {Muoproduction of J/ψ and the gluon distribution of the nucleon}, series = {Zeitschrift f{\"u}r Physik C Particles and Fields}, volume = {56}, journal = {Zeitschrift f{\"u}r Physik C Particles and Fields}, number = {1}, isbn = {1431-5858}, pages = {21 -- 28}, year = {1992}, abstract = {Measurements are presented of the inclusive distributions of the J/Ψ meson produced by muons of energy 200 GeV from an ammonia target. The gluon distribution of the nucleon has been derived from the data in the range 0.04 180 days). Greater/maintained stiffness indicated countermeasures were effective. Tissue stiffness was preserved in the majority of muscles (neck, shoulder, back, thigh) but Tibialis Anterior (foot lever muscle) stiffness decreased inflight vs. preflight (p < 0.0001; mean difference 149 N/m) in all 12 crewmembers. The calf muscles showed opposing effects, Gastrocnemius increasing in stiffness Soleus decreasing. Selective stiffness decrements indicate lack of preservation despite daily inflight countermeasures. This calls for more targeted exercises for lower leg muscles with vital roles as ankle joint stabilizers and in gait. Muscle stiffness is a digital biomarker for risk monitoring during future planetary explorations (Moon, Mars), for healthcare management in challenging environments or clinical disorders in people on Earth, to enable effective tailored exercise programmes.}, language = {en} } @article{LiphardtFernandezGonzaloAlbrachtetal.2023, author = {Liphardt, Anna-Maria and Fernandez-Gonzalo, Rodrigo and Albracht, Kirsten and Rittweger, J{\"o}rn and Vico, Laurence}, title = {Musculoskeletal research in human space flight - unmet needs for the success of crewed deep space exploration}, series = {npj Microgravity}, volume = {9}, journal = {npj Microgravity}, number = {Article number: 9}, publisher = {Springer Nature}, issn = {2373-8065}, doi = {10.1038/s41526-023-00258-3}, pages = {1 -- 9}, year = {2023}, abstract = {Based on the European Space Agency (ESA) Science in Space Environment (SciSpacE) community White Paper "Human Physiology - Musculoskeletal system", this perspective highlights unmet needs and suggests new avenues for future studies in musculoskeletal research to enable crewed exploration missions. The musculoskeletal system is essential for sustaining physical function and energy metabolism, and the maintenance of health during exploration missions, and consequently mission success, will be tightly linked to musculoskeletal function. Data collection from current space missions from pre-, during-, and post-flight periods would provide important information to understand and ultimately offset musculoskeletal alterations during long-term spaceflight. In addition, understanding the kinetics of the different components of the musculoskeletal system in parallel with a detailed description of the molecular mechanisms driving these alterations appears to be the best approach to address potential musculoskeletal problems that future exploratory-mission crew will face. These research efforts should be accompanied by technical advances in molecular and phenotypic monitoring tools to provide in-flight real-time feedback.}, language = {en} } @article{BurkhardtSchwarzPanetal.2009, author = {Burkhardt, Klaus and Schwarz, Sonja and Pan, Chengrui and Stelter, Felix and Kotliar, Konstantin and Eynatten, Maxilian von and Sollinger, Daniel and Lanzl, Ines and Heemann, Uwe and Baumann, Marcus}, title = {Myeloid-related protein 8/14 complex describes microcirculatory alterations in patients with type 2 diabetes and nephropathy}, series = {Cardiovascular Diabetology}, volume = {8}, journal = {Cardiovascular Diabetology}, number = {10}, publisher = {-}, isbn = {1475-2840}, pages = {1 -- 8}, year = {2009}, language = {en} } @article{HeinrichsUttingFrauenrathetal.2009, author = {Heinrichs, Uwe and Utting, Jane F. and Frauenrath, Tobias and Hezel, Fabian and Krombach, Gabriele A. and Hodenius, Michael A. J. and Kozerke, Sebastian and Niendorf, Thoralf}, title = {Myocardial T2 mapping free of distortion using susceptibility-weighted fast spin-echo imaging: A feasibility study at 1.5 T and 3.0 T}, series = {Magnetic Resonance in Medicine}, volume = {62}, journal = {Magnetic Resonance in Medicine}, number = {3}, publisher = {Wiley-Liss}, address = {New York}, issn = {1522-2594}, doi = {10.1002/mrm.22054}, pages = {822 -- 828}, year = {2009}, abstract = {This study demonstrates the feasibility of applying free-breathing, cardiac-gated, susceptibility-weighted fast spin-echo imaging together with black blood preparation and navigator-gated respiratory motion compensation for anatomically accurate T₂ mapping of the heart. First, T₂ maps are presented for oil phantoms without and with respiratory motion emulation (T₂ = (22.1 ± 1.7) ms at 1.5 T and T₂ = (22.65 ± 0.89) ms at 3.0 T). T₂ relaxometry of a ferrofluid revealed relaxivities of R2 = (477.9 ± 17) mM⁻¹s⁻¹ and R2 = (449.6 ± 13) mM⁻¹s⁻¹ for UFLARE and multiecho gradient-echo imaging at 1.5 T. For inferoseptal myocardial regions mean T₂ values of 29.9 ± 6.6 ms (1.5 T) and 22.3 ± 4.8 ms (3.0 T) were estimated. For posterior myocardial areas close to the vena cava T₂-values of 24.0 ± 6.4 ms (1.5 T) and 15.4 ± 1.8 ms (3.0 T) were observed. The merits and limitations of the proposed approach are discussed and its implications for cardiac and vascular T₂-mapping are considered.}, language = {en} } @misc{BlottnerHastermannMuckeltetal.2019, author = {Blottner, Dieter and Hastermann, Maria and Muckelt, Paul and Albracht, Kirsten and Schoenrock, Britt and Salanova, Michele and Warner, Martin and Gunga, Hans-Christian and Stokes, Maria}, title = {MYOTONES - Inflight muscle health status monitoring during long-duration space missions onboard the International Space Station: a single case study}, series = {IAC Papers Archive}, journal = {IAC Papers Archive}, publisher = {Pergamon}, address = {Oxford}, issn = {00741795}, pages = {2 Seiten}, year = {2019}, abstract = {The MYOTONES experiment is the first to monitor changes in the basic biomechanical properties (tone, elasticity and stiffness) of the resting human myofascial system due to microgravity with a oninvasive, portable device on board the ISS. The MyotonPRO device applies several brief mechanical stimuli to the surface of the skin, and the natural oscillation signals of the tissue beneath are detected and computed by the MyotonPRO. Thus, an objective, quick and easy determination of the state of the underlying tissue is possible. Two preflight, four inflight and four post flight measurements were performed on a male astronaut using the same 10 measurement points (MP) for each session. MPs were located on the plantar fascia, Achilles tendon, M. soleus, M. gastrocnemius, M. multifidus, M. splenius capitis, M. deltoideus anterior, M. rectus femoris, infrapatellar tendon, M. tibialis anterior. Subcutaneous tissues thickness above the MPs was measured using ultrasound imaging. Magnetic resonance images (MRI) of lower limb muscles and functional tests were also performed pre- and postflight. Our first measurements on board the ISS confirmed increased tone and stiffness of the lumbar multifidus muscle, an important trunk stabilizer, dysfunction of which is known to be associated with back pain. Furthermore, reduced tone and stiffness of Achilles tendon and plantar fascia were observed inflight vs. preflight, confirming previous findings from terrestrial analog studies and parabolic flights. Unexpectedly, the deltoid showed negative inflight changes in tone and stiffness, and increased elasticity, suggesting a potential risk of muscle atrophy in longer spaceflight that should be addressed by adequate inflight countermeasure protocols. Most values from limb and back MPS showed deflected patterns (in either directions) from inflight shortly after the re-entry phase on the landing day and one week later. Most parameter values then normalized to baseline after 3 weeks likely due to 1G re-adaptation and possible outcome of the reconditioning protocol. No major changes in subcutaneous tissues thickness above the MPs were found inflight vs preflight, suggesting no bias (i.e., fluid shift, extreme tissue thickening or loss). Pre- and postflight MRI and functional tests showed negligible changes in calf muscle size, power and force, which is likely due to training effects from current inflight exercise protocols. The MYOTONES experiment is currently ongoing to collect data from further crew members. The potential impact of this research is to better understand the effects of microgravity and countermeasures over the time course of an ISS mission cycle. This will enable exercise countermeasures to be tailored}, language = {en} } @incollection{KrollLudwigs2017, author = {Kroll-Ludwigs, Kathrin}, title = {Names of individuals}, series = {European Encyclopedia of Private International Law}, booktitle = {European Encyclopedia of Private International Law}, publisher = {Edward Elgar Publishing}, address = {Cheltenham, UK}, isbn = {9781782547228}, year = {2017}, language = {en} } @article{PoghossianAbouzarChristiaensetal.2007, author = {Poghossian, Arshak and Abouzar, Maryam H. and Christiaens, P. and Williams, O. A. and Haenen, K. and Wagner, P. and Sch{\"o}ning, Michael Josef}, title = {Nanocrystalline diamond-based field-effect (bio-)chemical sensor}, series = {8. Dresdner Sensor-Symposium : Sensoren f{\"u}r Umwelt, Klima und Sicherheit, Biosensoren und Biosysteme, Sensoren und Sensorsysteme f{\"u}r die Prozesstechnik, Trends in der Sensortechnik, Materialentwicklung f{\"u}r die Sensorik; 8. Dresdner Sensor-Symposium, 10. - 12. Dezember 2007, Dresden / Gerald Gerlach ... (Hg.)}, journal = {8. Dresdner Sensor-Symposium : Sensoren f{\"u}r Umwelt, Klima und Sicherheit, Biosensoren und Biosysteme, Sensoren und Sensorsysteme f{\"u}r die Prozesstechnik, Trends in der Sensortechnik, Materialentwicklung f{\"u}r die Sensorik; 8. Dresdner Sensor-Symposium, 10. - 12. Dezember 2007, Dresden / Gerald Gerlach ... (Hg.)}, publisher = {TUDpress, Verl. der Wissenschaften}, address = {Dresden}, isbn = {978-3-940046-45-1}, pages = {191 -- 194}, year = {2007}, language = {en} } @article{ChristiaensAbouzarPoghossianetal.2007, author = {Christiaens, P. and Abouzar, Maryam H. and Poghossian, Arshak and Wagner, Torsten and Bijnens, N. and Williams, O. A. and Daenen, M. and Haenen, K. and Sch{\"o}ning, Michael Josef and Wagner, P.}, title = {Nanocrystalline diamond-based field-effect capacitive pH sensor}, series = {Transducers '07 Eurosensors XXI : digest of technical papers ; the14th International Conference on Solid-State Sensors, Actuators and Microsystems, June 10-14, 2007, Lyon, France / Gilles Delapierre (Ed.)}, journal = {Transducers '07 Eurosensors XXI : digest of technical papers ; the14th International Conference on Solid-State Sensors, Actuators and Microsystems, June 10-14, 2007, Lyon, France / Gilles Delapierre (Ed.)}, publisher = {IEEE}, address = {Piscataway}, isbn = {1-4244-0841-5}, pages = {1891 -- 1894}, year = {2007}, language = {en} } @article{PoghossianAbouzarRazavietal.2009, author = {Poghossian, Arshak and Abouzar, Maryam H. and Razavi, A. and B{\"a}cker, Matthias and Bijnens, N. and Williams, O. A. and Haenen, K. and Moritz, W. and Wagner, P. and Sch{\"o}ning, Michael Josef}, title = {Nanocrystalline-diamond thin films with high pH and penicillin sensitivity prepared on a capacitive Si-SiO2 structure}, series = {Electrochimica Acta. 54 (2009), H. 25}, journal = {Electrochimica Acta. 54 (2009), H. 25}, isbn = {0013-4686}, pages = {5981 -- 5985}, year = {2009}, language = {en} } @article{MoraisGomesSilvaetal.2017, author = {Morais, Paulo V. and Gomes, Vanderley F., Jr. and Silva, Anielle C. A. and Dantas, Noelio O. and Sch{\"o}ning, Michael Josef and Siqueira, Jos{\´e} R., Jr.}, title = {Nanofilm of ZnO nanocrystals/carbon nanotubes as biocompatible layer for enzymatic biosensors in capacitive field-effect devices}, series = {Journal of Materials Science}, volume = {52}, journal = {Journal of Materials Science}, number = {20}, publisher = {Springer}, address = {Berlin}, issn = {1573-4803}, doi = {10.1007/s10853-017-1369-y}, pages = {12314 -- 12325}, year = {2017}, abstract = {The incorporation of nanomaterials that are biocompatible with different types of biological compounds has allowed the development of a new generation of biosensors applied especially in the biomedical field. In particular, the integration of film-based nanomaterials employed in field-effect devices can be interesting to develop biosensors with enhanced properties. In this paper, we studied the fabrication of sensitive nanofilms combining ZnO nanocrystals and carbon nanotubes (CNTs), prepared by means of the layer-by-layer (LbL) technique, in a capacitive electrolyte-insulator-semiconductor (EIS) structure for detecting glucose and urea. The ZnO nanocrystals were incorporated in a polymeric matrix of poly(allylamine) hydrochloride (PAH), and arranged with multi-walled CNTs in a LbL PAH-ZnO/CNTs film architecture onto EIS chips. The electrochemical characterizations were performed by capacitance-voltage and constant capacitance measurements, while the morphology of the films was characterized by atomic force microscopy. The enzymes glucose oxidase and urease were immobilized on film's surface for detection of glucose and urea, respectively. In order to obtain glucose and urea biosensors with optimized amount of sensitive films, we investigated the ideal number of bilayers for each detection system. The glucose biosensor showed better sensitivity and output signal for an LbL PAH-ZnO/CNTs nanofilm with 10 bilayers. On the other hand, the urea biosensor presented enhanced properties even for the first bilayer, exhibiting high sensitivity and output signal. The presence of the LbL PAH-ZnO/CNTs films led to biosensors with better sensitivity and enhanced response signal, demonstrating that the adequate use of nanostructured films is feasible for proof-of-concept biosensors with improved properties that may be employed for biomedical applications.}, language = {en} } @incollection{PoghossianSchoening2017, author = {Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Nanomaterial-Modified Capacitive Field-Effect Biosensors}, series = {Springer Series on Chemical Sensors and Biosensors (Methods and Applications)}, booktitle = {Springer Series on Chemical Sensors and Biosensors (Methods and Applications)}, publisher = {Springer}, address = {Berlin, Heidelberg}, doi = {10.1007/5346_2017_2}, pages = {1 -- 25}, year = {2017}, abstract = {The coupling of charged molecules, nanoparticles, and more generally, inorganic/organic nanohybrids with semiconductor field-effect devices based on an electrolyte-insulator-semiconductor (EIS) system represents a very promising strategy for the active tuning of electrochemical properties of these devices and, thus, opening new opportunities for label-free biosensing by the intrinsic charge of molecules. The simplest field-effect sensor is a capacitive EIS sensor, which represents a (bio-)chemically sensitive capacitor. In this chapter, selected examples of recent developments in the field of label-free biosensing using nanomaterial-modified capacitive EIS sensors are summarized. In the first part, we present applications of EIS sensors modified with negatively charged gold nanoparticles for the label-free electrostatic detection of positively charged small proteins and macromolecules, for monitoring the layer-by-layer formation of oppositely charged polyelectrolyte (PE) multilayers as well as for the development of an enzyme-based biomolecular logic gate. In the second part, examples of a label-free detection by means of EIS sensors modified with a positively charged weak PE layer are demonstrated. These include electrical detection of on-chip and in-solution hybridized DNA (deoxyribonucleic acid) as well as an EIS sensor with pH-responsive weak PE/enzyme multilayers for enhanced field-effect biosensing.}, language = {en} } @article{AbouzarIngebrandtPoghossianetal.2009, author = {Abouzar, Maryam H. and Ingebrandt, S. and Poghossian, Arshak and Zhang, Y. and Vu, X. T. and Moritz, W. and Sch{\"o}ning, Michael Josef}, title = {Nanoplate field-effect capacitive (bio-)chemical sensor array based on SOI structure}, series = {Procedia Chemistry. 1 (2009), H. 1}, journal = {Procedia Chemistry. 1 (2009), H. 1}, isbn = {1876-6196}, pages = {670 -- 673}, year = {2009}, language = {en} } @incollection{PoghossianWeilandSchoening2014, author = {Poghossian, Arshak and Weiland, Maryam and Sch{\"o}ning, Michael Josef}, title = {Nanoplate field-effect capacitors: a new transducer structure for multiparameter (bio-)chemical sensing}, series = {Multisensor system for chemical analysis : materials and sensors}, booktitle = {Multisensor system for chemical analysis : materials and sensors}, editor = {Lvova, Larisa and Kirsanov, Dmitry and di Natale, Corrado and Legin, Audrey}, edition = {1}, publisher = {Jenny Stanford Publishing}, address = {Singapore}, isbn = {978-981-4411-15-8 ; 978-981-4411-16-5}, doi = {10.1201/b15491-11}, pages = {333 -- 373}, year = {2014}, abstract = {An array of electrically isolated nanoplate field-effect silicon-on-insulator (SOI) capacitors as a new transducer structure for multiparameter (bio-)chemical sensing is presented. The proposed approach allows addressable biasing and electrical readout of multiple nanoplate field-effect capacitive (bio-)chemical sensors on the same SOI chip, as well as differential-mode measurements. The realized sensor chip has been applied for pH and penicillin concentration measurements, electrical monitoring of polyelectrolyte multilayer formation, and the label-free electrical detection of consecutive deoxyribonucleic acid (DNA) hybridization and denaturation events.}, language = {en} } @inproceedings{SchoeningAbdelghani2012, author = {Sch{\"o}ning, Michael Josef and Abdelghani, Adnane}, title = {Nanoscale Science and Technology (NS\&T'12) : Proceedings Book Humboldt Kolleg <2012, Tunisia> ; Tunisia, 17-19 March, 2012 / ed. by Michael J. Sch{\"o}ning ; Adnane Abdelghani}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:a96-opus-3544}, year = {2012}, abstract = {Proceedings of the 2nd Humboldt Kolleg, Hammamet, Tunisia Organizer: Alexander von Humboldt Stiftung, Germany. pdf 184 p. Welcome Address Dear Participants, Welcome to the 2nd Humboldt Kolleg in "Nanoscale Science and Technology" (NS\&T'12) in Tunisia, sponsored by the "Alexander von Humboldt" foundation. The NS\&T'12 multidisciplinary scientific program includes seven "hot" topics dealing with "Nanoscale Science and Technology" covering basic and application-oriented research as well as industrial (market) aspects: - Molecular Biophyics, Spectroscopy Techniques, Imaging Microscopy - Nanomaterials Synthesis for Medicine and Bio-chemical Sensors - Nanostructures, Semiconductors, Photonics and Nanodevices - New Technologies in Market Industry - Environment, Electro-chemistry, Bio-polymers and Fuel Cells - Nanomaterials, Photovoltaic, Modelling, Quantum Physics - Microelectronics, Sensors Networks and Embedded Systems We are deeply indebted to all members of the Scientific Committee and General Chairs for joint Sessions and to all speakers and chairmen, who have dedicated invaluable time and efforts for the realization of this event. On behalf of the Organizing Committee, we are cordially inviting you to join the conference and hope that your stay will be fruitful, rewarding and enjoyable. Prof. Dr. Michael J. Sch{\"o}ning, Prof. Dr. Adnane Abdelghani}, subject = {Biosensor}, language = {en} } @article{MansurovJandosovKerimkulovaetal.2014, author = {Mansurov, Z. A. and Jandosov, J. M. and Kerimkulova, A. R. and Azat, S. and Zhubanova, A. A. and Digel, Ilya and Savistkaya, I. S. and Akimbekov, Nuraly S. and Kistaubaeva, A. S.}, title = {Nanostructured carbon materials for biomedical use}, series = {Eurasian chemico-technological journal : quarterly journal of the International Higher Education Academy of Sciences}, volume = {15 (2013)}, journal = {Eurasian chemico-technological journal : quarterly journal of the International Higher Education Academy of Sciences}, number = {3}, publisher = {Institute of Combustion Problems}, address = {Almaty}, issn = {1562-3920}, doi = {10.18321/ectj224}, pages = {209 -- 217}, year = {2014}, abstract = {One of the priority trends of carbon nanotechnology is creation of nanocomposite systems. Such carbon nanostructured composites were produced using - raw materials based on the products of agricultural waste, such as grape stones, apricot stones, rice husk. These products have a - wide spectrum of application and can be obtained in large quantities. The Institute of Combustion Problems has carried out the work on synthesis of the nanostructured carbon sorbents for multiple applications including the field of biomedicine. The article presents the data on the synthesis and physico-chemical properties of carbonaceous sorbents using physicochemical methods of investigation: separation and purification of biomolecules; isolation of phytohormone - fusicoccin; adsorbent INGO-1 in the form of an adsorption column for blood detoxification, oral (entero) sorbent - INGO-2; the study of efferent and probiotic properties and sorption activity in regard to the lipopolysaccharide (LPS), new biocomposites - based on carbonized rice husk (CRH) and cellular microorganisms; the use of CRH in wound treatment. A new material for blood detoxication (INGO-1) has been obtained. Adsorption of p-cresyl sulfate and indoxyl sulfate has shown that active carbon adsorbent can remove clinically significant level of p-cresyl sulfate and indoxyl sulfate from human plasma. Enterosorbent INGO-2 possesses high adsorption activity in relation to Gram-negative bacteria and their endotoxins. INGO-2 slows down the growth of conditionally pathogenic microorganisms, without having a negative effect on bifido and lactobacteria. The use of enterosorbent INGO-2 for sorption therapy may provide a solution to a complex problem - detoxication of the digestive tract and normalization of the intestinal micro ecology. The immobilized probiotic called "Riso-lact" was registered at the Ministry of Health of the Republic of Kazakhstan as a biologically active food additive. The developed technology is patented and provides production of the medicine in the form of freeze-dried biomass immobilized in vials.}, language = {en} } @inproceedings{O'HerasDigelTemizArtmann2009, author = {O\'Heras, Carlos and Digel, Ilya and Temiz Artmann, Ayseg{\"u}l}, title = {Nanostructured carbon-based column for LPS/protein adsorption : [abstract]}, year = {2009}, abstract = {The absence of a general method for endotoxin removal from liquid interfaces gives an opportunity to find new methods and materials to overcome this gap. Activated nanostructured carbon is a promising material that showed good adsorption properties due to its vast pore network and high surface area. The aim of this study is to find the adsorption rates for a carboneous material produced at different temperatures, as well as to reveal possible differences between the performance of the material for each of the adsorbates used during the study (hemoglobin, serum albumin and lipopolysaccharide, LPS).}, subject = {Kohlenstofffaser}, language = {en} } @article{BlomeWilson1996, author = {Blome, Hans-Joachim and Wilson, Thomas L.}, title = {Nanotechnology and Orbital Debris}, series = {Engineering, construction, and operations in space V : proceedings of the Fifth International Conference on Space '96, Albuquerque, New Mexico, June 1-6, 1996 / sponsored by Aerospace Division of the American Society of Civil Engineers ... [et al.]; edite}, journal = {Engineering, construction, and operations in space V : proceedings of the Fifth International Conference on Space '96, Albuquerque, New Mexico, June 1-6, 1996 / sponsored by Aerospace Division of the American Society of Civil Engineers ... [et al.]; edite}, publisher = {The Society}, address = {New York}, isbn = {0-7844-0177-2}, pages = {328 -- 333}, year = {1996}, language = {en} } @article{Laack2014, author = {Laack, Walter van}, title = {Nature is much smarter than expected: the Genetic Code is not degenerate}, series = {American journal of humanities and social sciences}, volume = {Vol. 2}, journal = {American journal of humanities and social sciences}, number = {No. 1}, issn = {2329-0781 (Print) ; 2329-079X (Online)}, pages = {10 -- 12}, year = {2014}, abstract = {In any books about genetics it can still today be read that our genetic code is called "degenerate" because it is still believed that 43 = 64 triplets encode the 20 essential amino acids. Indeed we have to assume the inverse law, what means that 34 = 81 exact code positions are really effective for our genetic code and encode the amino acids, compiled to proteins. This very important discovery leads to two completely new results that are limits-overlooking: 1) 34 (=81) genetic code positions mean exactly the same number as there are stable and naturally existing chemical elements in our universe. This famous argument should now lead to some alternative, as well as new fundamental conclusions about our existence. 2) A genetic code positioning system shows that nature is much smarter than expected: mutations are made less dangerous than believed, because they won't be that easily able any more to cause severe damages in the protein-synthesis. This should also lead to some alternative views upon evolution of life.}, language = {en} } @inproceedings{NiedermeierClemensKowalskietal.2014, author = {Niedermeier, H. and Clemens, J. and Kowalski, Julia and Macht, S. and Heinen, D. and Hoffmann, R. and Linder, Peter}, title = {Navigation system for a research ice probe for antarctic glaciers}, series = {IEEE/ION Position, Location and Navigation Symposium (PLANS) ; 5-8 May 2014, Monterey, Calif.}, booktitle = {IEEE/ION Position, Location and Navigation Symposium (PLANS) ; 5-8 May 2014, Monterey, Calif.}, publisher = {IEEE}, address = {Piscataway, NJ}, organization = {Position, Location and Navigation Symposium <2014, Monterey, Calif.>}, isbn = {978-1-4799-3319-8}, pages = {959 -- 975}, year = {2014}, language = {en} } @article{KowalskiLinderZierkeetal.2016, author = {Kowalski, Julia and Linder, Peter and Zierke, S. and Wulfen, B. van and Clemens, J. and Konstantinidis, K. and Ameres, G. and Hoffmann, R. and Mikucki, J. and Tulaczyk, S. and Funke, O. and Blandfort, D. and Espe, Clemens and Feldmann, Marco and Francke, Gero and Hiecker, S. and Plescher, Engelbert and Sch{\"o}ngarth, Sarah and Dachwald, Bernd and Digel, Ilya and Artmann, Gerhard and Eliseev, D. and Heinen, D. and Scholz, F. and Wiebusch, C. and Macht, S. and Bestmann, U. and Reineking, T. and Zetzsche, C. and Schill, K. and F{\"o}rstner, R. and Niedermeier, H. and Szumski, A. and Eissfeller, B. and Naumann, U. and Helbing, K.}, title = {Navigation technology for exploration of glacier ice with maneuverable melting probes}, series = {Cold Regions Science and Technology}, journal = {Cold Regions Science and Technology}, number = {123}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0165-232X}, doi = {10.1016/j.coldregions.2015.11.006}, pages = {53 -- 70}, year = {2016}, abstract = {The Saturnian moon Enceladus with its extensive water bodies underneath a thick ice sheet cover is a potential candidate for extraterrestrial life. Direct exploration of such extraterrestrial aquatic ecosystems requires advanced access and sampling technologies with a high level of autonomy. A new technological approach has been developed as part of the collaborative research project Enceladus Explorer (EnEx). The concept is based upon a minimally invasive melting probe called the IceMole. The force-regulated, heater-controlled IceMole is able to travel along a curved trajectory as well as upwards. Hence, it allows maneuvers which may be necessary for obstacle avoidance or target selection. Maneuverability, however, necessitates a sophisticated on-board navigation system capable of autonomous operations. The development of such a navigational system has been the focal part of the EnEx project. The original IceMole has been further developed to include relative positioning based on in-ice attitude determination, acoustic positioning, ultrasonic obstacle and target detection integrated through a high-level sensor fusion. This paper describes the EnEx technology and discusses implications for an actual extraterrestrial mission concept.}, language = {en} } @article{DruckenmuellerGuentherElbers2018, author = {Druckenm{\"u}ller, Katharina and G{\"u}nther, Klaus and Elbers, Gereon}, title = {Near-infrared spectroscopy (NIRS) as a tool to monitor exhaust air from poultry operations}, series = {Science of the Total Environment}, volume = {630}, journal = {Science of the Total Environment}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0048-9697}, doi = {10.1016/j.scitotenv.2018.02.072}, pages = {536 -- 543}, year = {2018}, abstract = {Intensive poultry operation systems emit a considerable volume of inorganic and organic matter in the surrounding environment. Monitoring cleaning properties of exhaust air cleaning systems and to detect small but significant changes in emission characteristics during a fattening cycle is important for both emission and fattening process control. In the present study, we evaluated the potential of near-infrared spectroscopy (NIRS) combined with chemometric techniques as a monitoring tool of exhaust air from poultry operation systems. To generate a high-quality data set for evaluation, the exhaust air of two poultry houses was sampled by applying state-of-the-art filter sampling protocols. The two stables were identical except for one crucial difference, the presence or absence of an exhaust air cleaning system. In total, twenty-one exhaust air samples were collected at the two sites to monitor spectral differences caused by the cleaning device, and to follow changes in exhaust air characteristics during a fattening period. The total dust load was analyzed by gravimetric determination and included as a response variable in multivariate data analysis. The filter samples were directly measured with NIR spectroscopy. Principal component analysis (PCA), linear discriminant analysis (LDA), and factor analysis (FA) were effective in classifying the NIR exhaust air spectra according to fattening day and origin. The results indicate that the dust load and the composition of exhaust air (inorganic or organic matter) substantially influence the NIR spectral patterns. In conclusion, NIR spectroscopy as a tool is a promising and very rapid way to detect differences between exhaust air samples based on still not clearly defined circumstances triggered during a fattening period and the availability of an exhaust air cleaning system.}, language = {en} } @article{HellwigVolkmann2004, author = {Hellwig, Angelika and Volkmann, Lutz}, title = {Neighborhood and degree conditions for super-edge-connected bipartite digraphs}, series = {Results in mathematics}, volume = {Vol. 45}, journal = {Results in mathematics}, number = {Iss. 1-2}, issn = {1420-9012 (E-Journal); 1422-6383 (Print)}, pages = {45 -- 58}, year = {2004}, language = {en} } @article{HellwigVolkmann2005, author = {Hellwig, Angelika and Volkmann, Lutz}, title = {Neighborhood conditions for graphs and digraphs to be maximally edge-connected}, series = {Australasian journal of combinatorics}, volume = {Vol. 33}, journal = {Australasian journal of combinatorics}, issn = {10344942 ; 22023518}, pages = {265 -- 277}, year = {2005}, language = {en} } @article{BlankeHagenkampDoeringetal.2021, author = {Blanke, Tobias and Hagenkamp, Markus and D{\"o}ring, Bernd and G{\"o}ttsche, Joachim and Reger, Vitali and Kuhnhenne, Markus}, title = {Net-exergetic, hydraulic and thermal optimization of coaxial heat exchangers using fixed flow conditions instead of fixed flow rates}, series = {Geothermal Energy}, volume = {9}, journal = {Geothermal Energy}, number = {Article number: 19}, publisher = {Springer}, address = {Berlin}, issn = {2195-9706}, doi = {10.1186/s40517-021-00201-3}, pages = {23 Seiten}, year = {2021}, abstract = {Previous studies optimized the dimensions of coaxial heat exchangers using constant mass fow rates as a boundary condition. They show a thermal optimal circular ring width of nearly zero. Hydraulically optimal is an inner to outer pipe radius ratio of 0.65 for turbulent and 0.68 for laminar fow types. In contrast, in this study, fow conditions in the circular ring are kept constant (a set of fxed Reynolds numbers) during optimization. This approach ensures fxed fow conditions and prevents inappropriately high or low mass fow rates. The optimization is carried out for three objectives: Maximum energy gain, minimum hydraulic efort and eventually optimum net-exergy balance. The optimization changes the inner pipe radius and mass fow rate but not the Reynolds number of the circular ring. The thermal calculations base on Hellstr{\"o}m's borehole resistance and the hydraulic optimization on individually calculated linear loss of head coefcients. Increasing the inner pipe radius results in decreased hydraulic losses in the inner pipe but increased losses in the circular ring. The net-exergy diference is a key performance indicator and combines thermal and hydraulic calculations. It is the difference between thermal exergy fux and hydraulic efort. The Reynolds number in the circular ring is instead of the mass fow rate constant during all optimizations. The result from a thermal perspective is an optimal width of the circular ring of nearly zero. The hydraulically optimal inner pipe radius is 54\% of the outer pipe radius for laminar fow and 60\% for turbulent fow scenarios. Net-exergetic optimization shows a predominant infuence of hydraulic losses, especially for small temperature gains. The exact result depends on the earth's thermal properties and the fow type. Conclusively, coaxial geothermal probes' design should focus on the hydraulic optimum and take the thermal optimum as a secondary criterion due to the dominating hydraulics.}, language = {en} } @article{HartungSchiederKampmannetal.2006, author = {Hartung, Frank and Schieder, Andreas and Kampmann, Markus and Vorwerk, Marc}, title = {Network Supported Media Delivery in Ambient Networks (Netzwerkunterst{\"u}tzte Medienverteilung) / Schieder, Andreas ; Kampmann, Markus ; Hartung, Frank ; Vorwerk, Marc ; Rembarz, Ren{\´e}}, series = {it - Information Technology . 48 (2006), H. 5}, journal = {it - Information Technology . 48 (2006), H. 5}, isbn = {1611-2776}, pages = {264 -- 273}, year = {2006}, language = {en} } @book{Sander2004, author = {Sander, Volker}, title = {Networking Issues for Grid Infrastructure / Sander, Volker (ed.)}, publisher = {Global Grid Forum}, pages = {52 S.}, year = {2004}, language = {en} } @article{LaackRefisch1989, author = {Laack, Walter van and Refisch, A.}, title = {Neuralgic amyotrophy of the lumbar area. Case Report / Refisch, A. ; Laack, W. van}, series = {Archives of Orthopaedic and Trauma Surgery. 108 (1989), H. 5}, journal = {Archives of Orthopaedic and Trauma Surgery. 108 (1989), H. 5}, isbn = {0936-8051}, pages = {329 -- 332}, year = {1989}, language = {en} } @article{HoylerCizewskiColvin1988, author = {Hoyler, Friedrich and Cizewski, J. A. and Colvin, G. G.}, title = {Neutron capture on 193Ir and \&\#963;<\&\#963; SUB>max states in 195Ir / J. A. Cizewski ; G. G. Colvin ... F. Hoyler ...}, series = {Journal of Physics G. 14 (1988), H. S}, journal = {Journal of Physics G. 14 (1988), H. S}, isbn = {0305-4616}, pages = {S103 -- S108}, year = {1988}, language = {en} } @misc{RothTippkoetter2016, author = {Roth, J. and Tippk{\"o}tter, Nils}, title = {New Approach for Enzymatic Hydrolysis of Lignocellulose with Selective Diffusion Separation of the Monosaccharide Products}, series = {Chemie Ingenieur Technik}, volume = {88}, journal = {Chemie Ingenieur Technik}, number = {9}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201650301}, pages = {1237}, year = {2016}, abstract = {Enzymatic hydrolysis of lignocellulosic material plays an important role in the classical biorefinery approach. Apart from the pretreatment of the raw material, hydrolysis is the basis for the conversion of the cellulose and hemicellulose fraction into fermentable sugars. After hydrolysis, usually a solid-liquid separation takes place, in order to separate the residual plant material from the sugar-rich fraction, which can be subsequently used in a fermentation step. In order to factor out the separation step, the usage of in alginate immobilized crude cellulose fiber beads (CFBs) were evaluated. Pretreated cellulose fibers are incorporated in an alginate matrix together with the relevant enzymes. In doing so, sugars diffuse trough the alginate matrix, allowing a simplified delivery into the surrounding fluid. This again reduces product inhibition of the glucose on the enzyme catalysts. By means of standardized bead production the hydrolysis in lab scale was possible. First results show that liberation of glucose and xylose is possible, allowing a maximum total sugar yield of 75 \%.}, language = {en} } @article{GrotendorstScottAubertFrecon2006, author = {Grotendorst, Johannes and Scott, Tony C. and Aubert-Fr{\´e}con, Monique}, title = {New Approach for the Electronic Energies of the Hydrogen Molecular Ion / Scott, Tony C. ; Aubert-Fr{\´e}con, Monique ; Grotendorst, Johannes}, series = {Chemical Physics. 324 (2006), H. 2/3}, journal = {Chemical Physics. 324 (2006), H. 2/3}, isbn = {0301-0104}, pages = {323 -- 338}, year = {2006}, language = {en} } @article{GerhardsSanderZivkovicetal.2020, author = {Gerhards, Michael and Sander, Volker and Zivkovic, Miroslav and Belloum, Adam and Bubak, Marian}, title = {New approach to allocation planning of many-task workflows on clouds}, series = {Concurrency and Computation: Practice and Experience}, volume = {32}, journal = {Concurrency and Computation: Practice and Experience}, number = {2 Article e5404}, publisher = {Wiley}, address = {Chichester}, issn = {1532-0634}, doi = {10.1002/cpe.5404}, pages = {1 -- 16}, year = {2020}, abstract = {Experience has shown that a priori created static resource allocation plans are vulnerable to runtime deviations and hence often become uneconomic or highly exceed a predefined soft deadline. The assumption of constant task execution times during allocation planning is even more unlikely in a cloud environment where virtualized resources vary in performance. Revising the initially created resource allocation plan at runtime allows the scheduler to react on deviations between planning and execution. Such an adaptive rescheduling of a many-task application workflow is only feasible, when the planning time can be handled efficiently at runtime. In this paper, we present the static low-complexity resource allocation planning algorithm (LCP) applicable to efficiently schedule many-task scientific application workflows on cloud resources of different capabilities. The benefits of the presented algorithm are benchmarked against alternative approaches. The benchmark results show that LCP is not only able to compete against higher complexity algorithms in terms of planned costs and planned makespan but also outperforms them significantly by magnitudes of 2 to 160 in terms of required planning time. Hence, LCP is superior in terms of practical usability where low planning time is essential such as in our targeted online rescheduling scenario.}, language = {en} } @inproceedings{KleinLindemann1997, author = {Klein, Stefan and Lindemann, Markus}, title = {New architectures for web-enabled EDI-applications and their impact on VANS}, series = {Global business in practice : proceedings of the Tenth International Bled Electronic Commerce Conference BLED '97, Bled, Slovenia, June 9-11 1997}, booktitle = {Global business in practice : proceedings of the Tenth International Bled Electronic Commerce Conference BLED '97, Bled, Slovenia, June 9-11 1997}, editor = {Vogel, Douglas R.}, publisher = {Moderna organizacija}, address = {Kranj}, pages = {556 -- 573}, year = {1997}, language = {en} } @article{NamAroraBehbahanietal.2010, author = {Nam, J. and Arora, D. and Behbahani, Mehdi and Probst, M. and Benkowski, R. and Behr, M. and Pasquali, M.}, title = {New computational method in hemolysis analysis for artificial heart pump}, year = {2010}, language = {en} } @article{SimonisLuethWangetal.2004, author = {Simonis, A. and L{\"u}th, H. and Wang, J. and Sch{\"o}ning, Michael Josef}, title = {New concepts of miniaturised reference electrodes in silicon technology for potentiometric sensor systems}, series = {Sensors and Actuators B. 103 (2004), H. 1-2}, journal = {Sensors and Actuators B. 103 (2004), H. 1-2}, isbn = {0925-4005}, pages = {429 -- 435}, year = {2004}, language = {en} } @inproceedings{EdipGarevskiButenwegetal.2014, author = {Edip, Kemal and Garevski, Mihail and Butenweg, Christoph and Sheshov, Vlatko and Bojadjieva, Julijana and Gjorgjiev, Igor}, title = {New coupled finite-infinite element approach for wave propagation simulation of unbounded soil media}, series = {2nd European Conference on Earthquake Engineering and Seismology 2014 (2nd ECEES) : joint event of the 15th European Conference on Earthquake Engineering and the 34th General Assembly of the European Seismological Commission : Istanbul, Turkey, 25-29 August 2014 / European Association for Earthquake Engineering (EAEE) ; Vol. 2}, booktitle = {2nd European Conference on Earthquake Engineering and Seismology 2014 (2nd ECEES) : joint event of the 15th European Conference on Earthquake Engineering and the 34th General Assembly of the European Seismological Commission : Istanbul, Turkey, 25-29 August 2014 / European Association for Earthquake Engineering (EAEE) ; Vol. 2}, publisher = {Curran Associates, Inc.}, address = {Red Hook, NY}, organization = {European Conference on Earthquake Engineering and Seismology <2, 2014, Istanbul>}, isbn = {978-1-5108-1021-1}, pages = {1556 -- 1561}, year = {2014}, language = {en} } @article{ElQuardiStreckertBitzetal.2011, author = {El Quardi, A. and Streckert, J. and Bitz, Andreas and M{\"u}nkner, S. and Engel, J. and Hansen, V.}, title = {New fin-line devices for radiofrequency exposure of small biological samples in vitro allowing whole-cell patch clamp recordings}, series = {Bioelectromagnetics}, volume = {32}, journal = {Bioelectromagnetics}, number = {2}, publisher = {Wiley}, address = {Weinheim}, issn = {1521-186X}, doi = {10.1002/bem.20621}, pages = {102 -- 112}, year = {2011}, abstract = {The development and analysis of three waveguides for the exposure of small biological in vitro samples to mobile communication signals at 900 MHz (GSM, Global System for Mobile Communications), 1.8 GHz (GSM), and 2 GHz (UMTS, Universal Mobile Telecommunications System) is presented. The waveguides were based on a fin-line concept and the chamber containing the samples bathed in extracellular solution was placed onto two fins with a slot in between, where the exposure field concentrates. Measures were taken to allow for patch clamp recordings during radiofrequency (RF) exposure. The necessary power for the achievement of the maximum desired specific absorption rate (SAR) of 20 W/kg (average over the mass of the solution) was approximately Pin = 50 mW, Pin = 19 mW, and Pin = 18 mW for the 900 MHz, 1800 MHz, and 2 GHz devices, respectively. At 20 W/kg, a slight RF-induced temperature elevation in the solution of no more than 0.3 °C was detected, while no thermal offsets due to the electromagnetic exposure could be detected at the lower SAR settings (2, 0.2, and 0.02 W/kg). A deviation of 10\% from the intended solution volume yielded a calculated SAR deviation of 8\% from the desired value. A maximum ±10\% variation in the local SAR could occur when the position of the patch clamp electrode was altered within the area where the cells to be investigated were located.}, language = {en} } @article{SelmerPierikHeider2005, author = {Selmer, Thorsten and Pierik, Antonio J. and Heider, Johann}, title = {New glycyl radical enzymes catalysing key metabolic steps in anaerobic bacteria}, series = {Biological Chemistry. 386 (2005), H. 10}, journal = {Biological Chemistry. 386 (2005), H. 10}, isbn = {1431-6730}, pages = {981 -- 988}, year = {2005}, language = {en} } @article{MottaghySchellschmidtPopovetal.2005, author = {Mottaghy, Darius and Schellschmidt, R. and Popov, Y. A. and Clauser, C. and Kukkonen, I. T. and Nover, G. and Milanovsky, S. and Romushkevich, R. A.}, title = {New heat flow data from the immediate vicinity of the Kola super-deep borehole: Vertical variation in heat flow density confirmed and attributed to advection}, series = {Tectonophysics}, volume = {401}, journal = {Tectonophysics}, number = {1-2}, issn = {1879-3266}, doi = {10.1016/j.tecto.2005.03.005}, pages = {119 -- 142}, year = {2005}, language = {en} } @inproceedings{BlakeMoensHaleetal.2002, author = {Blake, D. and Moens, L. and Hale, M.-J. and Price, Henry and Keaney, David W. and Herrmann, Ulf}, title = {New heat transfer and storage fluids for parabolic trough solar thermal electric plants}, series = {Proceedings of the 11th SolarPACES International Symposium on Concentrated Solar Power and Chemical Energy Technologies : September 4 - 6, 2002, Zurich, Switzerland / Paul Scherrer Institut, PSI; ETH, Eidgen{\"o}ssische Technische Hochschule Z{\"u}rich}, booktitle = {Proceedings of the 11th SolarPACES International Symposium on Concentrated Solar Power and Chemical Energy Technologies : September 4 - 6, 2002, Zurich, Switzerland / Paul Scherrer Institut, PSI; ETH, Eidgen{\"o}ssische Technische Hochschule Z{\"u}rich}, editor = {Steinfeld, Aldo}, publisher = {Paul Scherrer Inst.}, address = {Villingen}, isbn = {3-9521409-3-7}, pages = {63 -- 66}, year = {2002}, language = {en} } @inproceedings{LindnerKolbRingbeck2008, author = {Lindner, Marvin and Kolb, Andreas and Ringbeck, Thorsten}, title = {New insights into the calibration of ToF-sensors}, series = {2008 IEEE Computer Society Conference on Computer Vision and Pattern Recognition workshops : Anchorage, AK, 23 - 28 June 2008}, booktitle = {2008 IEEE Computer Society Conference on Computer Vision and Pattern Recognition workshops : Anchorage, AK, 23 - 28 June 2008}, publisher = {IEEE Service Center}, address = {Piscataway, NJ}, isbn = {978-1-4244-2339-2}, pages = {1 -- 5}, year = {2008}, abstract = {Time-of-flight (ToF) sensors have become an alternative to conventional distance sensing techniques like laser scanners or image based stereo. ToF sensors provide full range distance information at high frame-rates and thus have a significant impact onto current research in areas like online object recognition, collision prevention or scene reconstruction. However, ToF cameras like the photonic mixer device (PMD) still exhibit a number of challenges regarding static and dynamic effects, e.g. systematic distance errors and motion artefacts, respectively. Sensor calibration techniques reducing static system errors have been proposed and show promising results. However, current calibration techniques in general need a large set of reference data in order to determine the corresponding parameters for the calibration model. This paper introduces a new calibration approach which combines different demodulation techniques for the ToF- camera 's reference signal. Examples show, that the resulting combined demodulation technique yields improved distance values based on only two required reference data sets.}, language = {en} } @article{OehlenschlaegerVolkmarStiefelmaieretal.2024, author = {Oehlenschl{\"a}ger, Katharina and Volkmar, Marianne and Stiefelmaier, Judith and Langsdorf, Alexander and Holtmann, Dirk and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {New insights into the influence of pre-culture on robust solvent production of C. acetobutylicum}, series = {Applied Microbiology and Biotechnology}, volume = {108}, journal = {Applied Microbiology and Biotechnology}, publisher = {Springer}, address = {Berlin, Heidelberg}, issn = {1432-0614}, doi = {10.1007/s00253-023-12981-8}, pages = {10 Seiten}, year = {2024}, abstract = {Clostridia are known for their solvent production, especially the production of butanol. Concerning the projected depletion of fossil fuels, this is of great interest. The cultivation of clostridia is known to be challenging, and it is difficult to achieve reproducible results and robust processes. However, existing publications usually concentrate on the cultivation conditions of the main culture. In this paper, the influence of cryo-conservation and pre-culture on growth and solvent production in the resulting main cultivation are examined. A protocol was developed that leads to reproducible cultivations of Clostridium acetobutylicum. Detailed investigation of the cell conservation in cryo-cultures ensured reliable cell growth in the pre-culture. Moreover, a reason for the acid crash in the main culture was found, based on the cultivation conditions of the pre-culture. The critical parameter to avoid the acid crash and accomplish the shift to the solventogenesis of clostridia is the metabolic phase in which the cells of the pre-culture were at the time of inoculation of the main culture; this depends on the cultivation time of the pre-culture. Using cells from the exponential growth phase to inoculate the main culture leads to an acid crash. To achieve the solventogenic phase with butanol production, the inoculum should consist of older cells which are in the stationary growth phase. Considering these parameters, which affect the entire cultivation process, reproducible results and reliable solvent production are ensured.}, language = {en} } @article{MuellerVeggianHaenniBeuscheretal.1980, author = {M{\"u}ller-Veggian, Mattea and Haenni, D. R. and Beuscher, H. and Bochev, B.}, title = {New isomeric state in ¹⁴⁴ Eu}, series = {Annual report 1979 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: A. F{\"a}ssler. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 72)}, journal = {Annual report 1979 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: A. F{\"a}ssler. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 72)}, publisher = {Kernforschungsanlage}, address = {J{\"u}lich}, pages = {48}, year = {1980}, language = {en} } @article{MuellerVeggianHaenniBeuscheretal.1979, author = {M{\"u}ller-Veggian, Mattea and Haenni, D. R. and Beuscher, H. and Lieder, R. M.}, title = {New isomeric state in ¹⁴⁵ Eu}, series = {Annual report 1978 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: A. F{\"a}ssler. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 36)}, journal = {Annual report 1978 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: A. F{\"a}ssler. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 36)}, publisher = {Kernforschungsanlage}, address = {J{\"u}lich}, pages = {26}, year = {1979}, language = {en} } @article{MuellerVeggianBeuscherHaennietal.1980, author = {M{\"u}ller-Veggian, Mattea and Beuscher, H. and Haenni, D. R. and Bochev, B.}, title = {New isomers in ¹⁴² Sm}, series = {Structure of medium-heavy nuclei, 1979 : proceedings of the 6. European Physical Soc. Nuclear Divisional Conference on the Structure of Medium-Heavy Nuclei held in Rhodes, Greece, 1-4 May 1979 / ed. Committee: G. S. Anagnostatos ... - (Conference series / Institute of Physics London, Bristol ; 49)}, journal = {Structure of medium-heavy nuclei, 1979 : proceedings of the 6. European Physical Soc. Nuclear Divisional Conference on the Structure of Medium-Heavy Nuclei held in Rhodes, Greece, 1-4 May 1979 / ed. Committee: G. S. Anagnostatos ... - (Conference series / Institute of Physics London, Bristol ; 49)}, publisher = {Inst. of Physics}, address = {Bristol}, isbn = {0-85498-140-3}, pages = {126}, year = {1980}, language = {en} } @article{MuellerVeggianBeuscherHaennietal.1979, author = {M{\"u}ller-Veggian, Mattea and Beuscher, H. and Haenni, D. R. and Bochev, B.}, title = {New isomers in ¹⁴² Sm}, series = {Annual report 1978 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: A. F{\"a}ssler. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 36)}, journal = {Annual report 1978 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: A. F{\"a}ssler. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 36)}, publisher = {Kernforschungsanlage}, address = {J{\"u}lich}, pages = {24}, year = {1979}, language = {en} }