@article{KuhnhenneRegerPyschnyetal.2020,
  author    = {Kuhnhenne, Markus and Reger, Vitali and Pyschny, Dominik and D{\"o}ring, Bernd},
  title     = {Influence of airtightness of steel sandwich panel joints on heat losses},
  series = {E3S Web of Conferences 12th Nordic Symposium on Building Physics (NSB 2020)},
  volume    = {172},
  journal   = {E3S Web of Conferences 12th Nordic Symposium on Building Physics (NSB 2020)},
  number    = {Art. 05008},
  publisher = {EDP Sciences},
  address   = {Les Ulis},
  doi       = {10.1051/e3sconf/202017205008},
  pages     = {6},
  year      = {2020},
  abstract  = {Energy saving ordinances requires that buildings must be designed in such a way that the heat transfer surface including the joints is permanently air impermeable. The prefabricated roof and wall panels in lightweight steel constructions are airtight in the area of the steel covering layers. The sealing of the panel joints contributes to fulfil the comprehensive requirements for an airtight building envelope. To improve the airtightness of steel sandwich panels, additional sealing tapes can be installed in the panel joint. The influence of these sealing tapes was evaluated by measurements carried out by the RWTH Aachen University - Sustainable Metal Building Envelopes. Different installation situations were evaluated by carrying out airtightness tests for different joint distances. In addition, the influence on the heat transfer coefficient was also evaluated using the Finite Element Method (FEM). The combination of obtained air volume flow and transmission losses enables to create an "effective heat transfer coefficient" due to transmission and infiltration. This summarizes both effects in one value and is particularly helpful for approximate calculations on energy efficiency.},
  language  = {en}
}
@article{MaurischatPerkins2020,
  author    = {Maurischat, Andreas and Perkins, Rudolph},
  title     = {Taylor coefficients of Anderson generating functions and Drinfeld torsion extensions},
  number    = {Vol. 18, No. 01},
  publisher = {World Scientific},
  address   = {Singapur},
  doi       = {10.1142/S1793042122500099},
  pages     = {113 -- 130},
  year      = {2020},
  abstract  = {We generalize our work on Carlitz prime power torsion extension to torsion extensions of Drinfeld modules of arbitrary rank. As in the Carlitz case, we give a description of these extensions in terms of evaluations of Anderson generating functions and their hyperderivatives at roots of unity. We also give a direct proof that the image of the Galois representation attached to the p-adic Tate module lies in the p-adic points of the motivic Galois group. This is a generalization of the corresponding result of Chang and Papanikolas for the t-adic case.},
  language  = {en}
}
@article{ElMoussaouiTalbiAtmaneetal.2020,
  author    = {El Moussaoui, Noureddine and Talbi, Sofian and Atmane, Ilyas and Kassmi, Khalil and Schwarzer, Klemens and Chayeb, Hamid and Bachiri, Najib},
  title     = {Feasibility of a new design of a Parabolic Trough Solar Thermal Cooker (PSTC)},
  series = {Solar Energy},
  volume    = {201},
  journal   = {Solar Energy},
  number    = {Vol. 201 (May 2020)},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0038-092X},
  doi       = {10.1016/j.solener.2020.03.079},
  pages     = {866 -- 871},
  year      = {2020},
  abstract  = {In this article, we describe the structure, the functioning, and the tests of parabolic trough solar thermal cooker (PSTC). This oven is designed to meet the needs of rural residents, including Urban, which requires stable cooking temperatures above 200 °C. The cooking by this cooker is based on the concentration of the sun's rays on a glass vacuum tube and heating of the oil circulate in a big tube, located inside the glass tube. Through two small tubes, associated with large tube, the heated oil, rise and heats the pot of cooking pot containing the food to be cooked (capacity of 5 kg). This cooker is designed in Germany and extensively tested in Morocco for use by the inhabitants who use wood from forests. During a sunny day, having a maximum solar radiation around 720 W/m2 and temperature ambient around 26 °C, maximum temperatures recorded of the small tube, the large tube and the center of the pot are respectively: 370 °C, 270 °C and 260 °C. The cooking process with food at high (fries, ..), we show that the cooking oil temperature rises to 200 °C, after 1 h of heating, the cooking is done at a temperature of 120 °C for 20 min. These temperatures are practically stable following variations and decreases in the intensity of irradiance during the day. The comparison of these results with those of the literature shows an improvement of 30-50 \% on the maximum value of the temperature with a heat storage that could reach 60 min of autonomy. All the results obtained show the good functioning of the PSTC and the feasibility of cooking food at high temperature (>200 °C).},
  language  = {en}
}
@article{OrzadaFiedlerBitzetal.2020,
  author    = {Orzada, Stephan and Fiedler, Thomas M. and Bitz, Andreas and Ladd, Mark E. and Quick, Harald H.},
  title     = {Local SAR compression with overestimation control to reduce maximum relative SAR overestimation and improve multi-channel RF array performance},
  series = {Magnetic Resonance Materials in Physics, Biology and Medicine},
  journal   = {Magnetic Resonance Materials in Physics, Biology and Medicine},
  number    = {34 (2021)},
  publisher = {Springer},
  address   = {Heidelberg},
  isbn      = {1352-8661},
  doi       = {10.1007/s10334-020-00890-0},
  pages     = {153 -- 164},
  year      = {2020},
  abstract  = {Objective In local SAR compression algorithms, the overestimation is generally not linearly dependent on actual local SAR. This can lead to large relative overestimation at low actual SAR values, unnecessarily constraining transmit array performance. Method Two strategies are proposed to reduce maximum relative overestimation for a given number of VOPs. The first strategy uses an overestimation matrix that roughly approximates actual local SAR; the second strategy uses a small set of pre-calculated VOPs as the overestimation term for the compression. Result Comparison with a previous method shows that for a given maximum relative overestimation the number of VOPs can be reduced by around 20\% at the cost of a higher absolute overestimation at high actual local SAR values. Conclusion The proposed strategies outperform a previously published strategy and can improve the SAR compression where maximum relative overestimation constrains the performance of parallel transmission.},
  language  = {en}
}
@article{UlmerBraunChengetal.2020,
  author    = {Ulmer, Jessica and Braun, Sebastian and Cheng, Chi-Tsun and Dowey, Steve and Wollert, J{\"o}rg},
  title     = {Human-Centered Gamification Framework for Manufacturing Systems},
  series = {Procedia CIRP},
  volume    = {93},
  journal   = {Procedia CIRP},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2212-8271},
  doi       = {10.1016/j.procir.2020.04.076},
  pages     = {670 -- 675},
  year      = {2020},
  abstract  = {While bringing new opportunities, the Industry 4.0 movement also imposes new challenges to the manufacturing industry and all its stakeholders. In this competitive environment, a skilled and engaged workforce is a key to success. Gamification can generate valuable feedbacks for improving employees' engagement and performance. Currently, Gamification in workspaces focuses on computer-based assignments and training, while tasks that require manual labor are rarely considered. This research provides an overview of Enterprise Gamification approaches and evaluates the challenges. Based on that, a skill-based Gamification framework for manual tasks is proposed, and a case study in the Industry 4.0 model factory is shown.},
  language  = {en}
}
@article{EveraersKarimiVarzanehFlecketal.2020,
  author    = {Everaers, Ralf and Karimi-Varzaneh, Hossein Ali and Fleck, Franz and Hojdis, Nils and Svaneborg, Carsten},
  title     = {Kremer-Grest Models for Commodity Polymer Melts: Linking Theory, Experiment, and Simulation at the Kuhn Scale},
  series = {Macromolecules},
  volume    = {53},
  journal   = {Macromolecules},
  number    = {6},
  publisher = {ACS Publications},
  address   = {Washington, DC},
  issn      = {1520-5835},
  doi       = {10.1021/acs.macromol.9b02428},
  pages     = {1901 -- 1916},
  year      = {2020},
  abstract  = {The Kremer-Grest (KG) polymer model is a standard model for studying generic polymer properties in molecular dynamics simulations. It owes its popularity to its simplicity and computational efficiency, rather than its ability to represent specific polymers species and conditions. Here we show that by tuning the chain stiffness it is possible to adapt the KG model to model melts of real polymers. In particular, we provide mapping relations from KG to SI units for a wide range of commodity polymers. The connection between the experimental and the KG melts is made at the Kuhn scale, i.e., at the crossover from the chemistry-specific small scale to the universal large scale behavior. We expect Kuhn scale-mapped KG models to faithfully represent universal properties dominated by the large scale conformational statistics and dynamics of flexible polymers. In particular, we observe very good agreement between entanglement moduli of our KG models and the experimental moduli of the target polymers.},
  language  = {en}
}
@article{MuellerLeiseLorenzetal.2020,
  author    = {M{\"u}ller, Tim M. and Leise, Philipp and Lorenz, Imke-Sophie and Altherr, Lena and Pelz, Peter F.},
  title     = {Optimization and validation of pumping system design and operation for water supply in high-rise buildings},
  series = {Optimization and Engineering},
  volume    = {2021},
  journal   = {Optimization and Engineering},
  number    = {22},
  publisher = {Springer},
  issn      = {1573-2924},
  doi       = {10.1007/s11081-020-09553-4},
  pages     = {643 -- 686},
  year      = {2020},
  abstract  = {The application of mathematical optimization methods for water supply system design and operation provides the capacity to increase the energy efficiency and to lower the investment costs considerably. We present a system approach for the optimal design and operation of pumping systems in real-world high-rise buildings that is based on the usage of mixed-integer nonlinear and mixed-integer linear modeling approaches. In addition, we consider different booster station topologies, i.e. parallel and series-parallel central booster stations as well as decentral booster stations. To confirm the validity of the underlying optimization models with real-world system behavior, we additionally present validation results based on experiments conducted on a modularly constructed pumping test rig. Within the models we consider layout and control decisions for different load scenarios, leading to a Deterministic Equivalent of a two-stage stochastic optimization program. We use a piecewise linearization as well as a piecewise relaxation of the pumps' characteristics to derive mixed-integer linear models. Besides the solution with off-the-shelf solvers, we present a problem specific exact solving algorithm to improve the computation time. Focusing on the efficient exploration of the solution space, we divide the problem into smaller subproblems, which partly can be cut off in the solution process. Furthermore, we discuss the performance and applicability of the solution approaches for real buildings and analyze the technical aspects of the solutions from an engineer's point of view, keeping in mind the economically important trade-off between investment and operation costs.},
  language  = {en}
}
@article{EckertAbbasiMangetal.2020,
  author    = {Eckert, Alexander and Abbasi, Mozhdeh and Mang, Thomas and Saalw{\"a}chter, Kay and Walther, Andreas},
  title     = {Structure, Mechanical Properties, and Dynamics of Polyethylenoxide/Nanoclay Nacre-Mimetic Nanocomposites},
  series = {Macromolecules},
  volume    = {53},
  journal   = {Macromolecules},
  number    = {5},
  publisher = {ACS Publications},
  address   = {Washington, DC},
  issn      = {1520-5835},
  doi       = {10.1021/acs.macromol.9b01931},
  pages     = {1716 -- 1725},
  year      = {2020},
  abstract  = {Nacre-mimetic nanocomposites based on high fractions of synthetic high-aspect-ratio nanoclays in combination with polymers are continuously pushing boundaries for advanced material properties, such as high barrier against oxygen, extraordinary mechanical behavior, fire shielding, and glass-like transparency. Additionally, they provide interesting model systems to study polymers under nanoconfinement due to the well-defined layered nanocomposite arrangement. Although the general behavior in terms of forming such layered nanocomposite materials using evaporative self-assembly and controlling the nanoclay gallery spacing by the nanoclay/polymer ratio is understood, some combinations of polymer matrices and nanoclay reinforcement do not comply with the established models. Here, we demonstrate a thorough characterization and analysis of such an unusual polymer/nanoclay pair that falls outside of the general behavior. Poly(ethylene oxide) (PEO) and sodium fluorohectorite form nacre-mimetic, lamellar nanocomposites that are completely transparent and show high mechanical stiffness and high gas barrier, but there is only limited expansion of the nanoclay gallery spacing when adding increasing amounts of polymer. This behavior is maintained for molecular weights of PEO varied over four orders of magnitude and can be traced back to depletion forces. By careful investigation via X-ray diffraction and proton low-resolution solid-state NMR, we are able to quantify the amount of mobile and immobilized polymer species in between the nanoclay galleries and around proposed tactoid stacks embedded in a PEO matrix. We further elucidate the unusual confined polymer dynamics, indicating a relevant role of specific surface interactions.},
  language  = {en}
}
@article{EngemannDuKallweitetal.2020,
  author    = {Engemann, Heiko and Du, Shengzhi and Kallweit, Stephan and C{\"o}nen, Patrick and Dawar, Harshal},
  title     = {OMNIVIL - an autonomous mobile manipulator for flexible production},
  series = {Sensors},
  volume    = {20},
  journal   = {Sensors},
  number    = {24, art. no. 7249},
  publisher = {MDPI},
  address   = {Basel},
  isbn      = {1424-8220},
  doi       = {10.3390/s20247249},
  pages     = {1 -- 30},
  year      = {2020},
  language  = {en}
}
@article{MoratFaudeHanssenetal.2020,
  author    = {Morat, Mareike and Faude, Oliver and Hanssen, Henner and Ludyga, Sebastian and Zacher, Jonas and Eibl, Angi and Albracht, Kirsten and Donath, Lars},
  title     = {Agility Training to Integratively Promote Neuromuscular, Cognitive, Cardiovascular and Psychosocial Function in Healthy Older Adults: A Study Protocol of a One-Year Randomized-Controlled Trial},
  series = {International Journal of Environmental Research and Public Health},
  volume    = {17},
  journal   = {International Journal of Environmental Research and Public Health},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1660-4601},
  doi       = {10.3390/ijerph17061853},
  pages     = {1 -- 14},
  year      = {2020},
  abstract  = {Exercise training effectively mitigates aging-induced health and fitness impairments. Traditional training recommendations for the elderly focus separately on relevant physiological fitness domains, such as balance, flexibility, strength and endurance. Thus, a more holistic and functional training framework is needed. The proposed agility training concept integratively tackles spatial orientation, stop and go, balance and strength. The presented protocol aims at introducing a two-armed, one-year randomized controlled trial, evaluating the effects of this concept on neuromuscular, cardiovascular, cognitive and psychosocial health outcomes in healthy older adults. Eighty-five participants were enrolled in this ongoing trial. Seventy-nine participants completed baseline testing and were block-randomized to the agility training group or the inactive control group. All participants undergo pre- and post-testing with interim assessment after six months. The intervention group currently receives supervised, group-based agility training twice a week over one year, with progressively demanding perceptual, cognitive and physical exercises. Knee extension strength, reactive balance, dual task gait speed and the Agility Challenge for the Elderly (ACE) serve as primary endpoints and neuromuscular, cognitive, cardiovascular, and psychosocial meassures serve as surrogate secondary outcomes. Our protocol promotes a comprehensive exercise training concept for older adults, that might facilitate stakeholders in health and exercise to stimulate relevant health outcomes without relying on excessively time-consuming physical activity recommendations.},
  language  = {en}
}
@article{KetelhutBrueggeGoelletal.2020,
  author    = {Ketelhut, Maike and Br{\"u}gge, G. M. and G{\"o}ll, Fabian and Braunstein, Bjoern and Albracht, Kirsten and Abel, Dirk},
  title     = {Adaptive iterative learning control of an industrial robot during neuromuscular training},
  series = {IFAC PapersOnLine},
  volume    = {53},
  journal   = {IFAC PapersOnLine},
  number    = {2},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2405-8963},
  doi       = {10.1016/j.ifacol.2020.12.741},
  pages     = {16468 -- 16475},
  year      = {2020},
  abstract  = {To prevent the reduction of muscle mass and loss of strength coming along with the human aging process, regular training with e.g. a leg press is suitable. However, the risk of training-induced injuries requires the continuous monitoring and controlling of the forces applied to the musculoskeletal system as well as the velocity along the motion trajectory and the range of motion. In this paper, an adaptive norm-optimal iterative learning control algorithm to minimize the knee joint loadings during the leg extension training with an industrial robot is proposed. The response of the algorithm is tested in simulation for patients with varus, normal and valgus alignment of the knee and compared to the results of a higher-order iterative learning control algorithm, a robust iterative learning control and a recently proposed conventional norm-optimal iterative learning control algorithm. Although significant improvements in performance are made compared to the conventional norm-optimal iterative learning control algorithm with a small learning factor, for the developed approach as well as the robust iterative learning control algorithm small steady state errors occur.},
  language  = {en}
}
@article{MalanHamerKaeneletal.2020,
  author    = {Malan, Leone and Hamer, Mark and K{\"a}nel, Roland von and Kotliar, Konstantin and Wyk, Roelof D. van and Lambert, Gavin W. and Vilser, Walthard and Ziemssen, Tjalf and Schlaich, Markus P. and Smith, Wayne and Magnusson, Martin and Wentzel, Annemarie and Myburgh, Carlien E. and Steyn, Hendrik S. and Malan, Nico T.},
  title     = {Delayed retinal vein recovery responses indicate both non-adaptation to stress as well as increased risk for stroke: the SABPA study},
  series = {Cardiovascular Journal of Africa},
  volume    = {26},
  journal   = {Cardiovascular Journal of Africa},
  number    = {31},
  publisher = {Clinics Cardive Publishing},
  address   = {Durbanville},
  issn      = {1680-0745},
  doi       = {10.5830/CVJA-2020-031},
  pages     = {1 -- 12},
  year      = {2020},
  language  = {en}
}
@article{StreeseKotliarDeiserothetal.2020,
  author    = {Streese, Lukas and Kotliar, Konstantin and Deiseroth, Arne and Infanger, Denis and Gugleta, Konstantin and Schmaderer, Christoph and Hanssen, Henner},
  title     = {Retinal endothelial function in cardiovascular risk patients: A randomized controlled exercise trial},
  series = {Scandinavian Journal of Medicine and Science in Sports},
  volume    = {30},
  journal   = {Scandinavian Journal of Medicine and Science in Sports},
  number    = {2},
  publisher = {Wiley},
  address   = {Oxford},
  issn      = {1600-0838},
  doi       = {10.1111/sms.13560},
  pages     = {272 -- 280},
  year      = {2020},
  abstract  = {The aim of this study was to investigate, for the first time, the effects of high-intensity interval training (HIIT) on retinal microvascular endothelial function in cardiovascular (CV) risk patients. In the randomized controlled trial, middle-aged and previously sedentary patients with increased CV risk (aged 58 ± 6 years) with ≥ two CV risk factors were randomized into a 12-week HIIT (n = 33) or control group (CG, n = 36) with standard physical activity recommendations. A blinded examiner measured retinal endothelial function by flicker light-induced maximal arteriolar (ADmax) and venular (VDmax) dilatation as well as the area under the arteriolar (AFarea) and venular (VFarea) flicker curve using a retinal vessel analyzer. Standardized assessments of CV risk factors, cardiorespiratory fitness, and retinal endothelial function were performed before and after HIIT. HIIT reduced body mass index, fat mass, and low-density lipoprotein and increased muscle mass and peak oxygen uptake (VO2peak). Both ADmax (pre: 2.7 ± 2.1\%, post: 3.0 ± 2.2\%, P = .018) and AFarea (pre: 32.6 ± 28.4\%*s, post: 37.7 ± 30.6\%*s, P = .016) increased after HIIT compared with CG (ADmax, pre: 3.2 ± 1.8\%, post: 2.9 ± 1.8\%, P = .254; AFarea, pre: 41.6 ± 28.5\%*s, post: 37.8 ± 27.0\%*s, P = .186). Venular function remained unchanged after HIIT. There was a significant association between ∆-change VO2peak and ∆-changes ADmax and AFarea (P = .026, R² = 0.073; P = .019, R² = 0.081, respectively). 12-weeks of HIIT improved retinal endothelial function in middle-aged patients with increased CV risk independent of the reduction in classical CV risk factors. Exercise has the potential to reverse or at least postpone progression of small vessel disease in older adults with increased CV risk under standard medication. Dynamic retinal vessel analysis seems to be a sensitive tool to detect treatment effects of exercise interventions on retinal microvascular endothelial function in middle-aged individuals with increased CV risk.},
  language  = {en}
}
@article{HamouKotliarTanetal.2020,
  author    = {Hamou, Hussam Aldin and Kotliar, Konstantin and Tan, Sonny Kian and Weiß, Christel and Blume, Christian and Clusmann, Hans and Schubert, Gerrit Alexander and Albanna, Walid},
  title     = {Surgical nuances and placement of subgaleal drains for supratentorial procedures—a prospective analysis of efficacy and outcome in 150 craniotomies},
  series = {Acta Neurochirurgica},
  volume    = {2020},
  journal   = {Acta Neurochirurgica},
  number    = {162},
  publisher = {Springer Nature},
  address   = {Cham},
  issn      = {0942-0940},
  doi       = {10.1007/s00701-019-04196-6},
  pages     = {729 -- 736},
  year      = {2020},
  abstract  = {Background For supratentorial craniotomy, surgical access, and closure technique, including placement of subgaleal drains, may vary considerably. The influence of surgical nuances on postoperative complications such as cerebrospinal fluid leakage or impaired wound healing overall remains largely unclear. With this study, we are reporting our experiences and the impact of our clinical routines on outcome in a prospectively collected data set. Method We prospectively observed 150 consecutive patients undergoing supratentorial craniotomy and recorded technical variables (type/length of incision, size of craniotomy, technique of dural and skin closure, type of dressing, and placement of subgaleal drains). Outcome variables (subgaleal hematoma/CSF collection, periorbital edema, impairment of wound healing, infection, and need for operative revision) were recorded at time of discharge and at late follow-up. Results Early subgaleal fluid collection was observed in 36.7\% (2.8\% at the late follow-up), and impaired wound healing was recorded in 3.3\% of all cases, with an overall need for operative revision of 6.7\%. Neither usage of dural sealants, lack of watertight dural closure, and presence of subgaleal drains, nor type of skin closure or dressing influenced outcome. Curved incisions, larger craniotomy, and tumor size, however, were associated with an increase in early CSF or hematoma collection (p < 0.0001, p = 0.001, p < 0.01 resp.), and larger craniotomy size was associated with longer persistence of subgaleal fluid collections (p < 0.05). Conclusions Based on our setting, individual surgical nuances such as the type of dural closure and the use of subgaleal drains resulted in a comparable complication rate and outcome. Subgaleal fluid collections were frequently observed after supratentorial procedures, irrespective of the closing technique employed, and resolve spontaneously in the majority of cases without significant sequelae. Our results are limited due to the observational nature in our single-center study and need to be validated by supportive prospective randomized design.},
  language  = {en}
}
@article{RamoshabaHuismanLammertynetal.2020,
  author    = {Ramoshaba, Nthai E. and Huisman, Hugo W. and Lammertyn, Leandi and Kotliar, Konstantin and Schutte, Aletta E. and Smith, Wayne},
  title     = {Retinal microvasculature and masked hypertension in young adults: the African-PREDICT study},
  series = {Hypertension Research},
  journal   = {Hypertension Research},
  number    = {43},
  publisher = {Springer Nature},
  address   = {Osaka},
  issn      = {1348-4214},
  doi       = {10.1038/s41440-020-0487-0},
  pages     = {1231 -- 1238},
  year      = {2020},
  abstract  = {Masked hypertension is known to induce microvascular complications. However, it is unclear whether early microvascular changes are already occurring in young, otherwise healthy adults. We therefore investigated whether retinal microvascular calibers and acute responses to a flicker stimulus are related to masked hypertension. We used the baseline data of 889 participants aged 20-30 years who were taking part in the African Prospective study on the Early Detection and Identification of Cardiovascular Disease and Hypertension. Clinic and 24-h ambulatory blood pressure were measured. The central retinal artery equivalent (CRAE) and central retinal vein equivalent were calculated from fundus images, and retinal vessel dilation was determined in response to flicker light-induced provocation. A smaller CRAE was observed in those with masked hypertension vs. those with normotension (157.1 vs. 161.2 measuring units, P < 0.001). In forward multivariable-adjusted regression analysis, only CRAE was negatively related to masked hypertension [adjusted R² = 0.267, β = -0.097 (95\% CI = -0.165; -0.029), P = 0.005], but other retinal microvascular parameters were not associated with masked hypertension. In multivariable logistic regression analyses, masked hypertension [OR = 2.333, (95\% CI = 1.316; 4.241), P = 0.004] was associated with a narrower CRAE. In young healthy adults, masked hypertension was associated with retinal arteriolar narrowing, thereby reflecting early microvascular alterations known to predict cardiovascular outcomes in later life.},
  language  = {en}
}
@article{SmithKotliarLammertynetal.2020,
  author    = {Smith, Wayne and Kotliar, Konstantin and Lammertyn, Leandi and Ramoshaba, Nthai E. and Vilser, Walthard and Huisman, Hugo W. and Schutte, Aletta E.},
  title     = {Retinal vessel caliber and caliber responses in true normotensive black and white adults: The African-PREDICT study},
  series = {Microvascular Research},
  volume    = {128},
  journal   = {Microvascular Research},
  number    = {Article 103937},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0026-2862},
  doi       = {10.1016/j.mvr.2019.103937},
  year      = {2020},
  abstract  = {Purpose Globally, a detrimental shift in cardiovascular disease risk factors and a higher mortality level are reported in some black populations. The retinal microvasculature provides early insight into the pathogenesis of systemic vascular diseases, but it is unclear whether retinal vessel calibers and acute retinal vessel functional responses differ between young healthy black and white adults. Methods We included 112 black and 143 white healthy normotensive adults (20-30 years). Retinal vessel calibers (central retinal artery and vein equivalent (CRAE and CRVE)) were calculated from retinal images and vessel caliber responses to flicker light induced provocation (FLIP) were determined. Additionally, ambulatory blood pressure (BP), anthropometry and blood samples were collected. Results The groups displayed similar 24 h BP profiles and anthropometry (all p > .24). Black participants demonstrated a smaller CRAE (158 ± 11 vs. 164 ± 11 MU, p < .001) compared to the white group, whereas CRVE was similar (p = .57). In response to FLIP, artery maximal dilation was greater in the black vs. white group (5.6 ± 2.1 vs. 3.3 ± 1.8\%; p < .001). Conclusions Already at a young age, healthy black adults showed narrower retinal arteries relative to the white population. Follow-up studies are underway to show if this will be related to increased risk for hypertension development. The reason for the larger vessel dilation responses to FLIP in the black population is unclear and warrants further investigation.},
  language  = {en}
}
@article{GoettenHavermannBraunetal.2020,
  author    = {G{\"o}tten, Falk and Havermann, Marc and Braun, Carsten and Marino, Matthew and Bil, Cees},
  title     = {Improved Form Factor for Drag Estimation of Fuselages with Various Cross Sections},
  series = {Journal of Aircraft},
  journal   = {Journal of Aircraft},
  publisher = {AIAA},
  address   = {Reston, Va.},
  issn      = {1533-3868},
  doi       = {10.2514/1.C036032},
  pages     = {1 -- 13},
  year      = {2020},
  abstract  = {The paper presents an aerodynamic investigation of 70 different streamlined bodies with fineness ratios ranging from 2 to 10. The bodies are chosen to idealize both unmanned and small manned aircraft fuselages and feature cross-sectional shapes that vary from circular to quadratic. The study focuses on friction and pressure drag in dependency of the individual body's fineness ratio and cross section. The drag forces are normalized with the respective body's wetted area to comply with an empirical drag estimation procedure. Although the friction drag coefficient then stays rather constant for all bodies, their pressure drag coefficients decrease with an increase in fineness ratio. Referring the pressure drag coefficient to the bodies' cross-sectional areas shows a distinct pressure drag minimum at a fineness ratio of about three. The pressure drag of bodies with a quadratic cross section is generally higher than for bodies of revolution. The results are used to derive an improved form factor that can be employed in a classic empirical drag estimation method. The improved formulation takes both the fineness ratio and cross-sectional shape into account. It shows superior accuracy in estimating streamlined body drag when compared with experimental data and other form factor formulations of the literature.},
  language  = {en}
}
@article{WildSchrezenmeierCzupallaetal.2020,
  author    = {Wild, Dominik and Schrezenmeier, Johannes and Czupalla, Markus and F{\"o}rstner, Roger},
  title     = {Thermal Characterization of additive manufactured Integral Structures for Phase Change Applications},
  series = {2020 International Conference on Environmental Systems},
  journal   = {2020 International Conference on Environmental Systems},
  publisher = {Texas Tech University},
  year      = {2020},
  abstract  = {"Infused Thermal Solutions" (ITS) introduces a method for passive thermal control to stabilize structural components thermally without active heating and cooling systems, by using phase change material (PCM) in combination with lattice - both embedded into an additive manufactured integral structure. The technology is currently under development. This paper presents the results of the thermal property measurements performed on additive manufactured ITS breadboards. Within the breadboard campaigns key characteristics of the additive manufactured specimens were derived: Mechanical parameters: specimen impermeability, minimum wall thickness, lattice structure, subsequent heat treatment. Thermal properties: thermo-optical surface properties of the additive manufactured raw material, thermal conductivity and specific heat capacity measurements. As a conclusion the paper introduces an overview of potential ITS hardware applications, expected to increase the thermal performance.},
  language  = {en}
}
@article{RaffeisAdjeiKyeremehVroomenetal.2020,
  author    = {Raffeis, Iris and Adjei-Kyeremeh, Frank and Vroomen, Uwe and Westhoff, Elmar and Bremen, Sebastian and Hohoi, Alexandru and B{\"u}hrig-Polaczek, Andreas},
  title     = {Qualification of a Ni-Cu alloy for the laser powder bed fusion process (LPBF): Its microstructure and mechanical properties},
  series = {Applied Sciences},
  volume    = {10},
  journal   = {Applied Sciences},
  number    = {Art. 3401},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2076-3417},
  doi       = {10.3390/app10103401},
  pages     = {1 -- 15},
  year      = {2020},
  abstract  = {As researchers continue to seek the expansion of the material base for additive manufacturing, there is a need to focus attention on the Ni-Cu group of alloys which conventionally has wide industrial applications. In this work, the G-NiCu30Nb casting alloy, a variant of the Monel family of alloys with Nb and high Si content is, for the first time, processed via the laser powder bed fusion process (LPBF). Being novel to the LPBF processes, optimum LPBF parameters were determined, and hardness and tensile tests were performed in as-built conditions and after heat treatment at 1000 °C. Microstructures of the as-cast and the as-built condition were compared. Highly dense samples (99.8\% density) were achieved after varying hatch distance (80 µm and 140 µm) with scanning speed (550 mm/s-1500 mm/s). There was no significant difference in microhardness between varied hatch distance print sets. Microhardness of the as-built condition (247 HV0.2) exceeded the as-cast microhardness (179 HV0.2.). Tensile specimens built in vertical (V) and horizontal (H) orientations revealed degrees of anisotropy and were superior to conventionally reported figures. Post heat treatment increased ductility from 20\% to 31\% (V), as well as from 16\% to 25\% (H), while ultimate tensile strength (UTS) and yield strength (YS) were considerably reduced.},
  language  = {en}
}
@article{BayerTemizArtmannDigeletal.2020,
  author    = {Bayer, Robin and Temiz Artmann, Ayseg{\"u}l and Digel, Ilya and Falkenstein, Julia and Artmann, Gerhard and Creutz, Till and Hescheler, J{\"u}rgen},
  title     = {Mechano-pharmacological testing of L-Type Ca²⁺ channel modulators via human vascular celldrum model},
  series = {Cellular Physiology and Biochemistry},
  volume    = {54},
  journal   = {Cellular Physiology and Biochemistry},
  publisher = {Cell Physiol Biochem Press},
  address   = {D{\"u}sseldorf},
  issn      = {1421-9778},
  doi       = {10.33594/000000225},
  pages     = {371 -- 383},
  year      = {2020},
  abstract  = {Background/Aims: This study aimed to establish a precise and well-defined working model, assessing pharmaceutical effects on vascular smooth muscle cell monolayer in-vitro. It describes various analysis techniques to determine the most suitable to measure the biomechanical impact of vasoactive agents by using CellDrum technology. Methods: The so-called CellDrum technology was applied to analyse the biomechanical properties of confluent human aorta muscle cells (haSMC) in monolayer. The cell generated tensions deviations in the range of a few N/m² are evaluated by the CellDrum technology. This study focuses on the dilative and contractive effects of L-type Ca²⁺ channel agonists and antagonists, respectively. We analyzed the effects of Bay K8644, nifedipine and verapamil. Three different measurement modes were developed and applied to determine the most appropriate analysis technique for the study purpose. These three operation modes are called, particular time mode" (PTM), "long term mode" (LTM) and "real-time mode" (RTM). Results: It was possible to quantify the biomechanical response of haSMCs to the addition of vasoactive agents using CellDrum technology. Due to the supplementation of 100nM Bay K8644, the tension increased approximately 10.6\% from initial tension maximum, whereas, the treatment with nifedipine and verapamil caused a significant decrease in cellular tension: 10nM nifedipine decreased the biomechanical stress around 6,5\% and 50nM verapamil by 2,8\%, compared to the initial tension maximum. Additionally, all tested measurement modes provide similar results while focusing on different analysis parameters. Conclusion: The CellDrum technology allows highly sensitive biomechanical stress measurements of cultured haSMC monolayers. The mechanical stress responses evoked by the application of vasoactive calcium channel modulators were quantified functionally (N/m²). All tested operation modes resulted in equal findings, whereas each mode features operation-related data analysis.},
  language  = {en}
}
@article{DigelKernGeenenetal.2020,
  author    = {Digel, Ilya and Kern, Inna and Geenen, Eva-Maria and Akimbekov, Nuraly S.},
  title     = {Dental plaque removal by ultrasonic toothbrushes},
  series = {dentistry journal},
  volume    = {8},
  journal   = {dentistry journal},
  number    = {28},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2304-6767},
  doi       = {10.3390/dj8010028},
  pages     = {1 -- 13},
  year      = {2020},
  abstract  = {With the variety of toothbrushes on the market, the question arises, which toothbrush is best suited to maintain oral health? This thematic review focuses first on plaque formation mechanisms and then on the plaque removal effectiveness of ultrasonic toothbrushes and their potential in preventing oral diseases like periodontitis, gingivitis, and caries. We overviewed the physical effects that occurred during brushing and tried to address the question of whether ultrasonic toothbrushes effectively reduced the microbial burden by increasing the hydrodynamic forces. The results of published studies show that electric toothbrushes, which combine ultrasonic and sonic (or acoustic and mechanic) actions, may have the most promising effect on good oral health. Existing ultrasonic/sonic toothbrush models do not significantly differ regarding the removal of dental biofilm and the reduction of gingival inflammation compared with other electrically powered toothbrushes, whereas the manual toothbrushes show a lower effectiveness.},
  language  = {en}
}
@article{GoettenHavermannBraunetal.2020,
  author    = {G{\"o}tten, Falk and Havermann, Marc and Braun, Carsten and Marino, Matthew and Bil, Cees},
  title     = {Wind-tunnel and CFD investigations of UAV landing gears and turrets - Improvements in empirical drag estimation},
  series = {Aerospace Science and Technology},
  volume    = {107},
  journal   = {Aerospace Science and Technology},
  number    = {Art. 106306},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1270-9638},
  doi       = {10.1016/j.ast.2020.106306},
  year      = {2020},
  abstract  = {This paper analyzes the drag characteristics of several landing gear and turret configurations that are representative of unmanned aircraft tricycle landing gears and sensor turrets. A variety of these components were constructed via 3D-printing and analyzed in a wind-tunnel measurement campaign. Both turrets and landing gears were attached to a modular fuselage that supported both isolated components and multiple components at a time. Selected cases were numerically investigated with a Reynolds-averaged Navier-Stokes approach that showed good accuracy when compared to wind-tunnel data. The drag of main gear struts could be significantly reduced via streamlining their cross-sectional shape and keeping load carrying capabilities similar. The attachment of wheels introduced interference effects that increased strut drag moderately but significantly increased wheel drag compared to isolated cases. Very similar behavior was identified for front landing gears. The drag of an electro-optical and infrared sensor turret was found to be much higher than compared to available data of a clean hemisphere-cylinder combination. This turret drag was merely influenced by geometrical features like sensor surfaces and the rotational mechanism. The new data of this study is used to develop simple drag estimation recommendations for main and front landing gear struts and wheels as well as sensor turrets. These recommendations take geometrical considerations and interference effects into account.},
  language  = {en}
}
@article{AkimbekovDigelSherelkhanetal.2020,
  author    = {Akimbekov, Nuraly S. and Digel, Ilya and Sherelkhan, Dinara K. and Lutfor, Afzalunnessa B. and Razzaque, Mohammed S.},
  title     = {Vitamin D and the Host-Gut Microbiome: A Brief Overview},
  series = {Acta Histochemica et Cytochemica},
  volume    = {53},
  journal   = {Acta Histochemica et Cytochemica},
  number    = {3},
  publisher = {Japan Society of Histochemistry and Cytochemistry},
  address   = {Osaka},
  issn      = {1347-5800},
  doi       = {10.1267/ahc.20011},
  pages     = {33 -- 42},
  year      = {2020},
  abstract  = {There is a growing body of evidence for the effects of vitamin D on intestinal host-microbiome interactions related to gut dysbiosis and bowel inflammation. This brief review highlights the potential links between vitamin D and gut health, emphasizing the role of vitamin D in microbiological and immunological mechanisms of inflammatory bowel diseases. A comprehensive literature search was carried out in PubMed and Google Scholar using combinations of keywords "vitamin D," "intestines," "gut microflora," "bowel inflammation". Only articles published in English and related to the study topic are included in the review. We discuss how vitamin D (a) modulates intestinal microbiome function, (b) controls antimicrobial peptide expression, and (c) has a protective effect on epithelial barriers in the gut mucosa. Vitamin D and its nuclear receptor (VDR) regulate intestinal barrier integrity, and control innate and adaptive immunity in the gut. Metabolites from the gut microbiota may also regulate expression of VDR, while vitamin D may influence the gut microbiota and exert anti-inflammatory and immune-modulating effects. The underlying mechanism of vitamin D in the pathogenesis of bowel diseases is not fully understood, but maintaining an optimal vitamin D status appears to be beneficial for gut health. Future studies will shed light on the molecular mechanisms through which vitamin D and VDR interactions affect intestinal mucosal immunity, pathogen invasion, symbiont colonization, and antimicrobial peptide expression.},
  language  = {en}
}
@article{BungCrookstonValero2020,
  author    = {Bung, Daniel Bernhard and Crookston, Brian M. and Valero, Daniel},
  title     = {Turbulent free-surface monitoring with an RGB-D sensor: the hydraulic jump case},
  series = {Journal of Hydraulic Research},
  journal   = {Journal of Hydraulic Research},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {1814-2079},
  doi       = {10.1080/00221686.2020.1844810},
  year      = {2020},
  language  = {en}
}
@article{EggertAlberts2020,
  author    = {Eggert, Mathias and Alberts, Jens},
  title     = {Frontiers of business intelligence and analytics 3.0: a taxonomy-based literature review and research agenda},
  series = {Business Research},
  volume    = {2020},
  journal   = {Business Research},
  number    = {13},
  publisher = {Springer},
  address   = {Heidelberg},
  issn      = {2198-2627},
  doi       = {10.1007/s40685-020-00108-y},
  pages     = {685 -- 739},
  year      = {2020},
  abstract  = {Researching the field of business intelligence and analytics (BI \& A) has a long tradition within information systems research. Thereby, in each decade the rapid development of technologies opened new room for investigation. Since the early 1950s, the collection and analysis of structured data were the focus of interest, followed by unstructured data since the early 1990s. The third wave of BI \& A comprises unstructured and sensor data of mobile devices. The article at hand aims at drawing a comprehensive overview of the status quo in relevant BI \& A research of the current decade, focusing on the third wave of BI \& A. By this means, the paper's contribution is fourfold. First, a systematically developed taxonomy for BI \& A 3.0 research, containing seven dimensions and 40 characteristics, is presented. Second, the results of a structured literature review containing 75 full research papers are analyzed by applying the developed taxonomy. The analysis provides an overview on the status quo of BI \& A 3.0. Third, the results foster discussions on the predicted and observed developments in BI \& A research of the past decade. Fourth, research gaps of the third wave of BI \& A research are disclosed and concluded in a research agenda.},
  language  = {en}
}
@article{TippkoetterRoth2020,
  author    = {Tippk{\"o}tter, Nils and Roth, Jasmine},
  title     = {Purified Butanol from Lignocellulose - Solvent-Impregnated Resins for an Integrated Selective Removal},
  series = {Chemie Ingenieur Technik},
  volume    = {92},
  journal   = {Chemie Ingenieur Technik},
  number    = {11},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1522-2640},
  doi       = {10.1002/cite.202000200},
  pages     = {1741 -- 1751},
  year      = {2020},
  abstract  = {In traditional microbial biobutanol production, the solvent must be recovered during fermentation process for a sufficient space-time yield. Thermal separation is not feasible due to the boiling point of n-butanol. As an integrated and selective solid-liquid separation alternative, solvent impregnated resins (SIRs) were applied. Two polymeric resins were evaluated and an extractant screening was conducted. Vacuum application with vapor collection in fixed-bed column as bioreactor bypass was successfully implemented as butanol desorption step. In course of further increasing process economics, fermentation with renewable lignocellulosic substrates was conducted using Clostridium acetobutylicum. Utilization of SIR was shown to be a potential strategy for solvent removal from fermentation broth, while application of a bypass column allows for product removal and recovery at once.},
  language  = {en}
}
@article{PogorelovaRogachevDigeletal.2020,
  author    = {Pogorelova, Natalia and Rogachev, Evgeniy and Digel, Ilya and Chernigova, Svetlana and Nardin, Dmitry},
  title     = {Bacterial Cellulose Nanocomposites: Morphology and Mechanical Properties},
  series = {Materials},
  volume    = {13},
  journal   = {Materials},
  number    = {12},
  publisher = {MDPI},
  address   = {Basel},
  isbn      = {1996-1944},
  doi       = {10.3390/ma13122849},
  pages     = {1 -- 16},
  year      = {2020},
  abstract  = {Bacterial cellulose (BC) is a promising material for biomedical applications due to its unique properties such as high mechanical strength and biocompatibility. This article describes the microbiological synthesis, modification, and characterization of the obtained BC-nanocomposites originating from symbiotic consortium Medusomyces gisevii. Two BC-modifications have been obtained: BC-Ag and BC-calcium phosphate (BC-Ca3(PO4)2). Structure and physicochemical properties of the BC and its modifications were investigated by scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), atomic force microscopy (AFM), and infrared Fourier spectroscopy as well as by measurements of mechanical and water holding/absorbing capacities. Topographic analysis of the surface revealed multicomponent thick fibrils (150-160 nm in diameter and about 15 µm in length) constituted by 50-60 nm nanofibrils weaved into a left-hand helix. Distinctive features of Ca-phosphate-modified BC samples were (a) the presence of 500-700 nm entanglements and (b) inclusions of Ca3(PO4)2 crystals. The samples impregnated with Ag nanoparticles exhibited numerous roundish inclusions, about 110 nm in diameter. The boundaries between the organic and inorganic phases were very distinct in both cases. The Ag-modified samples also showed a prominent waving pattern in the packing of nanofibrils. The obtained BC gel films possessed water-holding capacity of about 62.35 g/g. However, the dried (to a constant mass) BC-films later exhibited a low water absorption capacity (3.82 g/g). It was found that decellularized BC samples had 2.4 times larger Young's modulus and 2.2 times greater tensile strength as compared to dehydrated native BC films. We presume that this was caused by molecular compaction of the BC structure.},
  language  = {en}
}
@article{AbelKahmannMellonetal.2020,
  author    = {Abel, Alexander and Kahmann, Stephanie Lucina and Mellon, Stephen and Staat, Manfred and Jung, Alexander},
  title     = {An open-source tool for the validation of finite element models using three-dimensional full-field measurements},
  series = {Medical Engineering \& Physics},
  volume    = {77},
  journal   = {Medical Engineering \& Physics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1350-4533},
  doi       = {10.1016/j.medengphy.2019.10.015},
  pages     = {125 -- 129},
  year      = {2020},
  abstract  = {Three-dimensional (3D) full-field measurements provide a comprehensive and accurate validation of finite element (FE) models. For the validation, the result of the model and measurements are compared based on two respective point-sets and this requires the point-sets to be registered in one coordinate system. Point-set registration is a non-convex optimization problem that has widely been solved by the ordinary iterative closest point algorithm. However, this approach necessitates a good initialization without which it easily returns a local optimum, i.e. an erroneous registration. The globally optimal iterative closest point (Go-ICP) algorithm has overcome this drawback and forms the basis for the presented open-source tool that can be used for the validation of FE models using 3D full-field measurements. The capability of the tool is demonstrated using an application example from the field of biomechanics. Methodological problems that arise in real-world data and the respective implemented solution approaches are discussed.},
  language  = {en}
}
@article{VoegeleGrajewskiGovorukhaetal.2020,
  author    = {V{\"o}gele, Stefan and Grajewski, Matthias and Govorukha, Kristina and R{\"u}bbelke, Dirk},
  title     = {Challenges for the European steel industry: Analysis, possible consequences and impacts on sustainable development},
  series = {Applied Energy},
  volume    = {264},
  journal   = {Applied Energy},
  number    = {Article number: 114633},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0306-2619},
  doi       = {10.1016/j.apenergy.2020.114633},
  year      = {2020},
  abstract  = {The steel industry in the European Union (EU), important for the economy as a whole, faces various challenges. These are inter alia volatile prices for relevant input factors, uncertainties concerning the regulation of CO₂-emissions and market shocks caused by the recently introduced additional import duties in the US, which is an important sales market. We examine primary and secondary effects of these challenges on the steel industry in the EU and their impacts on European and global level. Developing and using a suitable meta-model, we analyze the competitiveness of key steel producing countries with respect to floor prices depending on selected cost factors and draw conclusions on the impacts in the trade of steel on emissions, energy demand, on the involvement of developing countries in the value chain as well on the need for innovations to avoid relocations of production. Hence, our study contributes to the assessment of sustainable industrial development, which is aimed by the Sustainability Development Goal "Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation countries". By applying information on country-specific Human Development Indexes (reflecting aspects of life expectancy, education, and per capita income), we show that relocating energy-intensive industries from the EU may not only increase global energy demand and CO₂-emissions, but may also be to the disadvantage of developing countries.},
  language  = {en}
}
@article{ValeroChansonBung2020,
  author    = {Valero, Daniel and Chanson, Hubert and Bung, Daniel Bernhard},
  title     = {Robust estimators for free surface turbulence characterization: A stepped spillway application},
  series = {Flow Measurement and Instrumentation},
  volume    = {76},
  journal   = {Flow Measurement and Instrumentation},
  number    = {Art. 101809},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0955-5986},
  doi       = {10.1016/j.flowmeasinst.2020.101809},
  year      = {2020},
  abstract  = {Robust estimators are parameters insensitive to the presence of outliers. However, they presume the shape of the variables' probability density function. This study exemplifies the sensitivity of turbulent quantities to the use of classic and robust estimators and the presence of outliers in turbulent flow depth time series. A wide range of turbulence quantities was analysed based upon a stepped spillway case study, using flow depths sampled with Acoustic Displacement Meters as the flow variable of interest. The studied parameters include: the expected free surface level, the expected fluctuation intensity, the depth skewness, the autocorrelation timescales, the vertical velocity fluctuation intensity, the perturbations celerity and the one-dimensional free surface turbulence spectrum. Three levels of filtering were utilised prior to applying classic and robust estimators, showing that comparable robustness can be obtained either using classic estimators together with an intermediate filtering technique or using robust estimators instead, without any filtering technique.},
  language  = {en}
}
@article{AkimbekovQiaoDigeletal.2020,
  author    = {Akimbekov, Nuraly S. and Qiao, Xiaohui and Digel, Ilya and Abdieva, Gulzhamal and Ualieva, Perizat and Zhubanova, Azhar},
  title     = {The effect of leonardite-derived amendments on soil microbiome structure and potato yield},
  series = {Agriculture},
  volume    = {10},
  journal   = {Agriculture},
  number    = {Art. 147},
  publisher = {MDPI},
  address   = {Basel},
  doi       = {10.3390/agriculture10050147},
  pages     = {1 -- 17},
  year      = {2020},
  abstract  = {Humic substances originating from various organic matters can ameliorate soil properties, stimulate plant growth, and improve nutrient uptake. Due to the low calorific heating value, leonardite is rather unsuitable as fuel. However, it may serve as a potential source of humic substances. This study was aimed at characterizing the leonardite-based soil amendments and examining the effect of their application on the soil microbial community, as well as on potato growth and tuber yield. A high yield (71.1\%) of humic acid (LHA) from leonardite has been demonstrated. Parental leonardite (PL) and LHA were applied to soil prior to potato cultivation. The 16S rRNA sequencing of soil samples revealed distinct relationships between microbial community composition and the application of leonardite-based soil amendments. Potato tubers were planted in pots in greenhouse conditions. The tubers were harvested at the mature stage for the determination of growth and yield parameters. The results demonstrated that the LHA treatments had a significant effect on increasing potato growth (54.9\%) and tuber yield (66.4\%) when compared to the control. The findings highlight the importance of amending leonardite-based humic products for maintaining the biogeochemical stability of soils, for keeping their healthy microbial community structure, and for increasing the agronomic productivity of potato plants.},
  language  = {en}
}
@article{RuppRiekeHandschuhetal.2020,
  author    = {Rupp, Matthias and Rieke, Christian and Handschuh, Nils and Kuperjans, Isabel},
  title     = {Economic and ecological optimization of electric bus charging considering variable electricity prices and CO₂eq intensities},
  series = {Transportation Research Part D: Transport and Environment},
  volume    = {81},
  journal   = {Transportation Research Part D: Transport and Environment},
  number    = {Article 102293},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1361-9209},
  doi       = {10.1016/j.trd.2020.102293},
  year      = {2020},
  abstract  = {In many cities, diesel buses are being replaced by electric buses with the aim of reducing local emissions and thus improving air quality. The protection of the environment and the health of the population is the highest priority of our society. For the transport companies that operate these buses, not only ecological issues but also economic issues are of great importance. Due to the high purchase costs of electric buses compared to conventional buses, operators are forced to use electric vehicles in a targeted manner in order to ensure amortization over the service life of the vehicles. A compromise between ecology and economy must be found in order to both protect the environment and ensure economical operation of the buses. In this study, we present a new methodology for optimizing the vehicles' charging time as a function of the parameters CO₂eq emissions and electricity costs. Based on recorded driving profiles in daily bus operation, the energy demands of conventional and electric buses are calculated for the passenger transportation in the city of Aachen in 2017. Different charging scenarios are defined to analyze the influence of the temporal variability of CO₂eq intensity and electricity price on the environmental impact and economy of the bus. For every individual day of a year, charging periods with the lowest and highest costs and emissions are identified and recommendations for daily bus operation are made. To enable both the ecological and economical operation of the bus, the parameters of electricity price and CO₂ are weighted differently, and several charging periods are proposed, taking into account the priorities previously set. A sensitivity analysis is carried out to evaluate the influence of selected parameters and to derive recommendations for improving the ecological and economic balance of the battery-powered electric vehicle. In all scenarios, the optimization of the charging period results in energy cost savings of a maximum of 13.6\% compared to charging at a fixed electricity price. The savings potential of CO₂eq emissions is similar, at 14.9\%. From an economic point of view, charging between 2 a.m. and 4 a.m. results in the lowest energy costs on average. The CO₂eq intensity is also low in this period, but midday charging leads to the largest savings in CO₂eq emissions. From a life cycle perspective, the electric bus is not economically competitive with the conventional bus. However, from an ecological point of view, the electric bus saves on average 37.5\% CO₂eq emissions over its service life compared to the diesel bus. The reduction potential is maximized if the electric vehicle exclusively consumes electricity from solar and wind power.},
  language  = {en}
}
@article{Stulpe2020,
  author    = {Stulpe, Werner},
  title     = {Pairwise coexistence of effects versus coexistence},
  series = {Journal of Physics: Conference Series},
  volume    = {1638},
  journal   = {Journal of Physics: Conference Series},
  number    = {012004},
  publisher = {IOP},
  address   = {Bristol},
  issn      = {1742-6596},
  doi       = {10.1088/1742-6596/1638/1/012004},
  pages     = {1 -- 21},
  year      = {2020},
  language  = {en}
}
@article{GossmannThomasHorvathetal.2020,
  author    = {Gossmann, Matthias and Thomas, Ulrich and Horv{\´a}th, Andr{\´a}s and Dragicevic, Elena and Stoelzle-Feix, Sonja and Jung, Alexander and Raman, Aravind Hariharan and Staat, Manfred and Linder, Peter},
  title     = {A higher-throughput approach to investigate cardiac contractility in vitro under physiological mechanical conditions},
  series = {Journal of Pharmacological and Toxicological Methods},
  volume    = {105},
  journal   = {Journal of Pharmacological and Toxicological Methods},
  number    = {Article 106843},
  publisher = {Elsevier},
  address   = {New York, NY},
  doi       = {10.1016/j.vascn.2020.106843},
  year      = {2020},
  language  = {en}
}
@article{PoghossianJablonskiMolinnusetal.2020,
  author    = {Poghossian, Arshak and Jablonski, Melanie and Molinnus, Denise and Wege, Christina and Sch{\"o}ning, Michael Josef},
  title     = {Field-Effect Sensors for Virus Detection: From Ebola to SARS-CoV-2 and Plant Viral Enhancers},
  series = {Frontiers in Plant Science},
  volume    = {11},
  journal   = {Frontiers in Plant Science},
  number    = {Article 598103},
  publisher = {Frontiers},
  address   = {Lausanne},
  doi       = {10.3389/fpls.2020.598103},
  pages     = {1 -- 14},
  year      = {2020},
  abstract  = {Coronavirus disease 2019 (COVID-19) is a novel human infectious disease provoked by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, no specific vaccines or drugs against COVID-19 are available. Therefore, early diagnosis and treatment are essential in order to slow the virus spread and to contain the disease outbreak. Hence, new diagnostic tests and devices for virus detection in clinical samples that are faster, more accurate and reliable, easier and cost-efficient than existing ones are needed. Due to the small sizes, fast response time, label-free operation without the need for expensive and time-consuming labeling steps, the possibility of real-time and multiplexed measurements, robustness and portability (point-of-care and on-site testing), biosensors based on semiconductor field-effect devices (FEDs) are one of the most attractive platforms for an electrical detection of charged biomolecules and bioparticles by their intrinsic charge. In this review, recent advances and key developments in the field of label-free detection of viruses (including plant viruses) with various types of FEDs are presented. In recent years, however, certain plant viruses have also attracted additional interest for biosensor layouts: Their repetitive protein subunits arranged at nanometric spacing can be employed for coupling functional molecules. If used as adapters on sensor chip surfaces, they allow an efficient immobilization of analyte-specific recognition and detector elements such as antibodies and enzymes at highest surface densities. The display on plant viral bionanoparticles may also lead to long-time stabilization of sensor molecules upon repeated uses and has the potential to increase sensor performance substantially, compared to conventional layouts. This has been demonstrated in different proof-of-concept biosensor devices. Therefore, richly available plant viral particles, non-pathogenic for animals or humans, might gain novel importance if applied in receptor layers of FEDs. These perspectives are explained and discussed with regard to future detection strategies for COVID-19 and related viral diseases.},
  language  = {en}
}
@article{FingerBraunBil2020,
  author    = {Finger, Felix and Braun, Carsten and Bil, Cees},
  title     = {Comparative assessment of parallel-hybrid-electric propulsion systems for four different aircraft},
  series = {Journal of Aircraft},
  volume    = {57},
  journal   = {Journal of Aircraft},
  number    = {5},
  publisher = {AIAA},
  address   = {Reston, Va.},
  issn      = {1533-3868},
  doi       = {10.2514/1.C035897},
  year      = {2020},
  abstract  = {Until electric energy storage systems are ready to allow fully electric aircraft, the combination of combustion engine and electric motor as a hybrid-electric propulsion system seems to be a promising intermediate solution. Consequently, the design space for future aircraft is expanded considerably, as serial hybrid-electric, parallel hybrid-electric, fully electric, and conventional propulsion systems must all be considered. While the best propulsion system depends on a multitude of requirements and considerations, trends can be observed for certain types of aircraft and certain types of missions. This Paper provides insight into some factors that drive a new design toward either conventional or hybrid propulsion systems. General aviation aircraft, regional transport aircraft vertical takeoff and landing air taxis, and unmanned aerial vehicles are chosen as case studies. Typical missions for each class are considered, and the aircraft are analyzed regarding their takeoff mass and primary energy consumption. For these case studies, a high-level approach is chosen, using an initial sizing methodology. Only parallel-hybrid-electric powertrains are taken into account. Aeropropulsive interaction effects are neglected. Results indicate that hybrid-electric propulsion systems should be considered if the propulsion system is sized by short-duration power constraints. However, if the propulsion system is sized by a continuous power requirement, hybrid-electric systems offer hardly any benefit.},
  language  = {en}
}
@article{OezsoyluKizildagSchoeningetal.2020,
  author    = {{\"O}zsoylu, Dua and Kizildag, Sefa and Sch{\"o}ning, Michael Josef and Wagner, Torsten},
  title     = {Differential chemical imaging of extracellular acidification within microfluidic channels using a plasma-functionalized light-addressable potentiometric sensor (LAPS)},
  series = {Physics in Medicine},
  volume    = {10},
  journal   = {Physics in Medicine},
  number    = {100030},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2352-4510},
  doi       = {10.1016/j.phmed.2020.100030},
  pages     = {8},
  year      = {2020},
  abstract  = {Extracellular acidification is a basic indicator for alterations in two vital metabolic pathways: glycolysis and cellular respiration. Measuring these alterations by monitoring extracellular acidification using cell-based biosensors such as LAPS plays an important role in studying these pathways whose disorders are associated with numerous diseases including cancer. However, the surface of the biosensors must be specially tailored to ensure high cell compatibility so that cells can represent more in vivo-like behavior, which is critical to gain more realistic in vitro results from the analyses, e.g., drug discovery experiments. In this work, O2 plasma patterning on the LAPS surface is studied to enhance surface features of the sensor chip, e.g., wettability and biofunctionality. The surface treated with O2 plasma for 30 s exhibits enhanced cytocompatibility for adherent CHO-K1 cells, which promotes cell spreading and proliferation. The plasma-modified LAPS chip is then integrated into a microfluidic system, which provides two identical channels to facilitate differential measurements of the extracellular acidification of CHO-K1 cells. To the best of our knowledge, it is the first time that extracellular acidification within microfluidic channels is quantitatively visualized as differential (bio-)chemical images.},
  language  = {en}
}
@article{MartinVaqueroKleefeld2020,
  author    = {Mart{\´i}n-Vaquero, J. and Kleefeld, Andreas},
  title     = {Solving nonlinear parabolic PDEs in several dimensions: Parallelized ESERK codes},
  series = {Journal of Computational Physics},
  journal   = {Journal of Computational Physics},
  number    = {423},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0021-9991},
  doi       = {10.1016/j.jcp.2020.109771},
  year      = {2020},
  abstract  = {There is a very large number of very important situations which can be modeled with nonlinear parabolic partial differential equations (PDEs) in several dimensions. In general, these PDEs can be solved by discretizing in the spatial variables and transforming them into huge systems of ordinary differential equations (ODEs), which are very stiff. Therefore, standard explicit methods require a large number of iterations to solve stiff problems. But implicit schemes are computationally very expensive when solving huge systems of nonlinear ODEs. Several families of Extrapolated Stabilized Explicit Runge-Kutta schemes (ESERK) with different order of accuracy (3 to 6) are derived and analyzed in this work. They are explicit methods, with stability regions extended, along the negative real semi-axis, quadratically with respect to the number of stages s, hence they can be considered to solve stiff problems much faster than traditional explicit schemes. Additionally, they allow the adaptation of the step length easily with a very small cost. Two new families of ESERK schemes (ESERK3 and ESERK6) are derived, and analyzed, in this work. Each family has more than 50 new schemes, with up to 84.000 stages in the case of ESERK6. For the first time, we also parallelized all these new variable step length and variable number of stages algorithms (ESERK3, ESERK4, ESERK5, and ESERK6). These parallelized strategies allow to decrease times significantly, as it is discussed and also shown numerically in two problems. Thus, the new codes provide very good results compared to other well-known ODE solvers. Finally, a new strategy is proposed to increase the efficiency of these schemes, and it is discussed the idea of combining ESERK families in one code, because typically, stiff problems have different zones and according to them and the requested tolerance the optimum order of convergence is different.},
  language  = {en}
}
@article{Gaigall2020,
  author    = {Gaigall, Daniel},
  title     = {Rothman-Woodroofe symmetry test statistic revisited},
  series = {Computational Statistics \& Data Analysis},
  volume    = {2020},
  journal   = {Computational Statistics \& Data Analysis},
  number    = {142},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0167-9473},
  doi       = {10.1016/j.csda.2019.106837},
  pages     = {Artikel 106837},
  year      = {2020},
  abstract  = {The Rothman-Woodroofe symmetry test statistic is revisited on the basis of independent but not necessarily identically distributed random variables. The distribution-freeness if the underlying distributions are all symmetric and continuous is obtained. The results are applied for testing symmetry in a meta-analysis random effects model. The consistency of the procedure is discussed in this situation as well. A comparison with an alternative proposal from the literature is conducted via simulations. Real data are analyzed to demonstrate how the new approach works in practice.},
  language  = {en}
}
@article{Gaigall2020,
  author    = {Gaigall, Daniel},
  title     = {Testing marginal homogeneity of a continuous bivariate distribution with possibly incomplete paired data},
  series = {Metrika},
  volume    = {2020},
  journal   = {Metrika},
  number    = {83},
  publisher = {Springer},
  issn      = {1435-926X},
  doi       = {10.1007/s00184-019-00742-5},
  pages     = {437 -- 465},
  year      = {2020},
  abstract  = {We discuss the testing problem of homogeneity of the marginal distributions of a continuous bivariate distribution based on a paired sample with possibly missing components (missing completely at random). Applying the well-known two-sample Cr{\´a}mer-von-Mises distance to the remaining data, we determine the limiting null distribution of our test statistic in this situation. It is seen that a new resampling approach is appropriate for the approximation of the unknown null distribution. We prove that the resulting test asymptotically reaches the significance level and is consistent. Properties of the test under local alternatives are pointed out as well. Simulations investigate the quality of the approximation and the power of the new approach in the finite sample case. As an illustration we apply the test to real data sets.},
  language  = {en}
}
@article{DrummEmhardtKoketal.2020,
  author    = {Drumm, Christian and Emhardt, Selina N. and Kok, Ellen M. and Jarodzka, Halzka and Brand-Gruwel, Saskia and van Gog, Tamara},
  title     = {How Experts Adapt Their Gaze Behavior When Modeling a Task to Novices},
  series = {Cognitive science},
  volume    = {44},
  journal   = {Cognitive science},
  number    = {9},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1551-6709},
  doi       = {10.1111/cogs.12893},
  pages     = {26},
  year      = {2020},
  abstract  = {Domain experts regularly teach novice students how to perform a task. This often requires them to adjust their behavior to the less knowledgeable audience and, hence, to behave in a more didactic manner. Eye movement modeling examples (EMMEs) are a contemporary educational tool for displaying experts' (natural or didactic) problem-solving behavior as well as their eye movements to learners. While research on expert-novice communication mainly focused on experts' changes in explicit, verbal communication behavior, it is as yet unclear whether and how exactly experts adjust their nonverbal behavior. This study first investigated whether and how experts change their eye movements and mouse clicks (that are displayed in EMMEs) when they perform a task naturally versus teach a task didactically. Programming experts and novices initially debugged short computer codes in a natural manner. We first characterized experts' natural problem-solving behavior by contrasting it with that of novices. Then, we explored the changes in experts' behavior when being subsequently instructed to model their task solution didactically. Experts became more similar to novices on measures associated with experts' automatized processes (i.e., shorter fixation durations, fewer transitions between code and output per click on the run button when behaving didactically). This adaptation might make it easier for novices to follow or imitate the expert behavior. In contrast, experts became less similar to novices for measures associated with more strategic behavior (i.e., code reading linearity, clicks on run button) when behaving didactically.},
  language  = {en}
}
@article{Biewendt2020,
  author    = {Biewendt, Marcel},
  title     = {Sustainable development: A quantitative analysis regarding the impact of resource rents on state welfare from 2002 to 2017},
  series = {SocioEconomic Challenges},
  volume    = {4},
  journal   = {SocioEconomic Challenges},
  number    = {4},
  publisher = {ARMG Publishing},
  address   = {Sumy},
  issn      = {2520-6214},
  doi       = {10.21272/sec.4(4).119-131.2020},
  pages     = {119 -- 131},
  year      = {2020},
  abstract  = {This paper uses a quantitative analysis to examine the interdependence and impact of resource rents on socio-economic development from 2002 to 2017. Nigeria and Norway have been chosen as reference countries due to their abundance of natural resources by similar economic performance, while the ranking in the Human Development Index differs dramatically. As the Human Development Index provides insight into a country's cultural and socio-economic characteristics and development in addition to economic indicators, it allows a comparison of the two countries. The hypothesis presented and discussed in this paper was researched before. A qualitative research approach was used in the author's master's thesis "The Human Development Index (HDI) as a Reflection of Resource Abundance (using Nigeria and Norway as a case study)" in 2018. The management of scarce resources is an important aspect in the development of modern countries and those on the threshold of becoming industrialised nations. The effects of a mistaken resource management are not only of a purely economic nature but also of a social and socio-economic nature. In order to present a partial aspect of these dependencies and influences this paper uses a quantitative analysis to examine the interdependence and impact of resource rents on socio-economic development from 2002 to 2017. Nigeria and Norway have been chosen as reference countries due to their abundance of natural resources by similar economic performance, while the ranking in the Human Development Index differs significantly. As the Human Development Index provides insight into a country's cultural and socio-economic characteristics and development in addition to economic indicators, it allows a comparison of the two countries. This paper found out in a holistic perspective that (not or poorly managed) resource wealth in itself has a negative impact on socio-economic development and significantly reduces the productivity of the citizens of a state. This is expressed in particular for the years 2002 till 2017 in a negative correlation of GDP per capita and HDI value with the share respectively the size of resources in the GDP of a country.},
  language  = {en}
}
@article{KleefeldPieronek2020,
  author    = {Kleefeld, Andreas and Pieronek, J.},
  title     = {Elastic transmission eigenvalues and their computation via the method of fundamental solutions},
  series = {Applicable Analysis},
  volume    = {100},
  journal   = {Applicable Analysis},
  number    = {16},
  publisher = {Taylore \& Francis},
  address   = {London},
  issn      = {1563-504X},
  doi       = {10.1080/00036811.2020.1721473},
  pages     = {3445 -- 3462},
  year      = {2020},
  abstract  = {A stabilized version of the fundamental solution method to catch ill-conditioning effects is investigated with focus on the computation of complex-valued elastic interior transmission eigenvalues in two dimensions for homogeneous and isotropic media. Its algorithm can be implemented very shortly and adopts to many similar partial differential equation-based eigenproblems as long as the underlying fundamental solution function can be easily generated. We develop a corroborative approximation analysis which also implicates new basic results for transmission eigenfunctions and present some numerical examples which together prove successful feasibility of our eigenvalue recovery approach.},
  language  = {en}
}
@article{SattlerRoegerSchwarzboezletal.2020,
  author    = {Sattler, Johannes Christoph and R{\"o}ger, Marc and Schwarzb{\"o}zl, Peter and Buck, Reiner and Macke, Ansgar and Raeder, Christian and G{\"o}ttsche, Joachim},
  title     = {Review of heliostat calibration and tracking control methods},
  series = {Solar Energy},
  volume    = {207},
  journal   = {Solar Energy},
  publisher = {Elsevier},
  address   = {Amsterdam},
  doi       = {10.1016/j.solener.2020.06.030},
  pages     = {110 -- 132},
  year      = {2020},
  abstract  = {Large scale central receiver systems typically deploy between thousands to more than a hundred thousand heliostats. During solar operation, each heliostat is aligned individually in such a way that the overall surface normal bisects the angle between the sun's position and the aim point coordinate on the receiver. Due to various tracking error sources, achieving accurate alignment ≤1 mrad for all the heliostats with respect to the aim points on the receiver without a calibration system can be regarded as unrealistic. Therefore, a calibration system is necessary not only to improve the aiming accuracy for achieving desired flux distributions but also to reduce or eliminate spillage. An overview of current larger-scale central receiver systems (CRS), tracking error sources and the basic requirements of an ideal calibration system is presented. Leading up to the main topic, a description of general and specific terms on the topics heliostat calibration and tracking control clarifies the terminology used in this work. Various figures illustrate the signal flows along various typical components as well as the corresponding monitoring or measuring devices that indicate or measure along the signal (or effect) chain. The numerous calibration systems are described in detail and classified in groups. Two tables allow the juxtaposition of the calibration methods for a better comparison. In an assessment, the advantages and disadvantages of individual calibration methods are presented.},
  language  = {en}
}
@article{FingerGoettenBraunetal.2020,
  author    = {Finger, Felix and G{\"o}tten, Falk and Braun, Carsten and Bil, Cees},
  title     = {Mass, primary energy, and cost: the impact of optimization objectives on the initial sizing of hybrid-electric general aviation aircraft},
  series = {CEAS Aeronautical Journal},
  volume    = {2020},
  journal   = {CEAS Aeronautical Journal},
  number    = {11},
  publisher = {Springer},
  address   = {Heidelberg},
  issn      = {1869-5590},
  doi       = {10.1007/s13272-020-00449-8},
  pages     = {713 -- 730},
  year      = {2020},
  abstract  = {For short take-off and landing (STOL) aircraft, a parallel hybrid-electric propulsion system potentially offers superior performance compared to a conventional propulsion system, because the short-take-off power requirement is much higher than the cruise power requirement. This power-matching problem can be solved with a balanced hybrid propulsion system. However, there is a trade-off between wing loading, power loading, the level of hybridization, as well as range and take-off distance. An optimization method can vary design variables in such a way that a minimum of a particular objective is attained. In this paper, a comparison between the optimization results for minimum mass, minimum consumed primary energy, and minimum cost is conducted. A new initial sizing algorithm for general aviation aircraft with hybrid-electric propulsion systems is applied. This initial sizing methodology covers point performance, mission performance analysis, the weight estimation process, and cost estimation. The methodology is applied to the design of a STOL general aviation aircraft, intended for on-demand air mobility operations. The aircraft is sized to carry eight passengers over a distance of 500 km, while able to take off and land from short airstrips. Results indicate that parallel hybrid-electric propulsion systems must be considered for future STOL aircraft.},
  language  = {en}
}
@article{TranStaat2020,
  author    = {Tran, Ngoc Trinh and Staat, Manfred},
  title     = {Direct plastic structural design under lognormally distributed strength by chance constrained programming},
  series = {Optimization and Engineering},
  volume    = {21},
  journal   = {Optimization and Engineering},
  number    = {1},
  publisher = {Springer Nature},
  address   = {Cham},
  issn      = {1573-2924},
  doi       = {10.1007/s11081-019-09437-2},
  pages     = {131 -- 157},
  year      = {2020},
  abstract  = {We propose the so-called chance constrained programming model of stochastic programming theory to analyze limit and shakedown loads of structures under random strength with a lognormal distribution. A dual chance constrained programming algorithm is developed to calculate simultaneously both the upper and lower bounds of the plastic collapse limit and the shakedown limit. The edge-based smoothed finite element method (ES-FEM) is used with three-node linear triangular elements.},
  language  = {en}
}
@article{PoghossianSchoening2020,
  author    = {Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {Capacitive field-effect eis chemical sensors and biosensors: A status report},
  series = {Sensors},
  volume    = {20},
  journal   = {Sensors},
  number    = {19},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s20195639},
  pages     = {Artikel 5639},
  year      = {2020},
  abstract  = {Electrolyte-insulator-semiconductor (EIS) field-effect sensors belong to a new generation of electronic chips for biochemical sensing, enabling a direct electronic readout. The review gives an overview on recent advances and current trends in the research and development of chemical sensors and biosensors based on the capacitive field-effect EIS structure—the simplest field-effect device, which represents a biochemically sensitive capacitor. Fundamental concepts, physicochemical phenomena underlying the transduction mechanism and application of capacitive EIS sensors for the detection of pH, ion concentrations, and enzymatic reactions, as well as the label-free detection of charged molecules (nucleic acids, proteins, and polyelectrolytes) and nanoparticles, are presented and discussed.},
  language  = {en}
}
@article{RoepkeKoehlerDruryetal.2020,
  author    = {Roepke, Rene and K{\"o}hler, Klemens and Drury, Vincent and Schroeder, Ulrik and Wolf, Martin R. and Meyer, Ulrike},
  title     = {A pond full of phishing games - analysis of learning games for anti-phishing education},
  series = {Model-driven Simulation and Training Environments for Cybersecurity. MSTEC 2020},
  journal   = {Model-driven Simulation and Training Environments for Cybersecurity. MSTEC 2020},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-62433-0},
  doi       = {10.1007/978-3-030-62433-0_32020},
  pages     = {41 -- 60},
  year      = {2020},
  abstract  = {Game-based learning is a promising approach to anti-phishing education, as it fosters motivation and can help reduce the perceived difficulty of the educational material. Over the years, several prototypes for game-based applications have been proposed, that follow different approaches in content selection, presentation, and game mechanics. In this paper, a literature and product review of existing learning games is presented. Based on research papers and accessible applications, an in-depth analysis was conducted, encompassing target groups, educational contexts, learning goals based on Bloom's Revised Taxonomy, and learning content. As a result of this review, we created the publications on games (POG) data set for the domain of anti-phishing education. While there are games that can convey factual and conceptual knowledge, we find that most games are either unavailable, fail to convey procedural knowledge or lack technical depth. Thus, we identify potential areas of improvement for games suitable for end-users in informal learning contexts.},
  language  = {en}
}
@article{FingerBraunBil2020,
  author    = {Finger, Felix and Braun, Carsten and Bil, Cees},
  title     = {Impact of Battery Performance on the Initial Sizing of Hybrid-Electric General Aviation Aircraft},
  series = {Journal of Aerospace Engineering},
  volume    = {33},
  journal   = {Journal of Aerospace Engineering},
  number    = {3},
  publisher = {ASCE},
  address   = {Reston, Va.},
  issn      = {1943-5525},
  doi       = {10.1061/(ASCE)AS.1943-5525.0001113},
  year      = {2020},
  abstract  = {Studies suggest that hybrid-electric aircraft have the potential to generate fewer emissions and be inherently quieter when compared to conventional aircraft. By operating combustion engines together with an electric propulsion system, synergistic benefits can be obtained. However, the performance of hybrid-electric aircraft is still constrained by a battery's energy density and discharge rate. In this paper, the influence of battery performance on the gross mass for a four-seat general aviation aircraft with a hybrid-electric propulsion system is analyzed. For this design study, a high-level approach is chosen, using an innovative initial sizing methodology to determine the minimum required aircraft mass for a specific set of requirements and constraints. Only the peak-load shaving operational strategy is analyzed. Both parallel- and serial-hybrid propulsion configurations are considered for two different missions. The specific energy of the battery pack is varied from 200 to 1,000 W⋅h/kg, while the discharge time, and thus the normalized discharge rating (C-rating), is varied between 30 min (2C discharge rate) and 2 min (30C discharge rate). With the peak-load shaving operating strategy, it is desirable for hybrid-electric aircraft to use a light, low capacity battery system to boost performance. For this case, the battery's specific power rating proved to be of much higher importance than for full electric designs, which have high capacity batteries. Discharge ratings of 20C allow a significant take-off mass reduction aircraft. The design point moves to higher wing loadings and higher levels of hybridization if batteries with advanced technology are used.},
  language  = {en}
}
@article{HoffstadtPohenDickeetal.2020,
  author    = {Hoffstadt, Kevin and Pohen, Gino D. and Dicke, Max D. and Paulsen, Svea and Krafft, Simone and Zang, Joachim W. and Fonseca-Zang, Warde A. da and Leite, Athaydes and Kuperjans, Isabel},
  title     = {Challenges and prospects of biogas from energy cane as supplement to bioethanol production},
  series = {Agronomy},
  volume    = {10},
  journal   = {Agronomy},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2073-4395},
  doi       = {10.3390/agronomy10060821},
  year      = {2020},
  abstract  = {Innovative breeds of sugar cane yield up to 2.5 times as much organic matter as conventional breeds, resulting in a great potential for biogas production. The use of biogas production as a complementary solution to conventional and second-generation ethanol production in Brazil may increase the energy produced per hectare in the sugarcane sector. Herein, it was demonstrated that through ensiling, energy cane can be conserved for six months; the stored cane can then be fed into a continuous biogas process. This approach is necessary to achieve year-round biogas production at an industrial scale. Batch tests revealed specific biogas potentials between 400 and 600 LN/kgVS for both the ensiled and non-ensiled energy cane, and the specific biogas potential of a continuous biogas process fed with ensiled energy cane was in the same range. Peak biogas losses through ensiling of up to 27\% after six months were observed. Finally, compared with second-generation ethanol production using energy cane, the results indicated that biogas production from energy cane may lead to higher energy yields per hectare, with an average energy yield of up to 162 MWh/ha. Finally, the Farm²CBG concept is introduced, showing an approach for decentralized biogas production.},
  language  = {en}
}
@article{BiewendtBoehnertBlaschke2020,
  author    = {Biewendt, Marcel and B{\"o}hnert, Arno and Blaschke, Florian},
  title     = {The repercussions of the digital twin in the automotive industry on the new marketing logic},
  series = {European Journal of Marketing and Economics},
  volume    = {4},
  journal   = {European Journal of Marketing and Economics},
  number    = {1},
  publisher = {Revistia},
  address   = {London},
  issn      = {2601-8659},
  doi       = {10.26417/229eim64f},
  pages     = {68 -- 73},
  year      = {2020},
  abstract  = {Rapid development of virtual and data acquisition technology makes Digital Twin Technology (DT) one of the fundamental areas of research, while DT is one of the most promissory developments for the achievement of Industry 4.0. 48\% percent of organisations implementing the Internet of Things are already using DT or plan to use DT in 2020. The global market for DT is expected to grow by 38 percent annually, reaching USD16 billion by 2023. In addition, the number of participating organisations using digital twins is expected to triple by 2022. DTs are characterised by the integration between physical and virtual spaces. The driving idea for DT is to develop, test and build our devices in a virtual environment. The objective of this paper is to study the impact of DT in the automotive industry on the new marketing logic. This paper outlines the current challenges and possible directions for the future DT in marketing. This paper will be helpful for managers in the industry to use the advantages and potentials of DT.},
  language  = {en}
}
@article{BreussKleefeld2020,
  author    = {Breuß, Michael and Kleefeld, Andreas},
  title     = {Implicit monotone difference methods for scalar conservation laws with source terms},
  series = {Acta Mathematica Vietnamica},
  volume    = {45},
  journal   = {Acta Mathematica Vietnamica},
  publisher = {Springer Singapore},
  address   = {Singapore},
  issn      = {2315-4144},
  doi       = {10.1007/s40306-019-00354-1},
  pages     = {709 -- 738},
  year      = {2020},
  abstract  = {In this article, a concept of implicit methods for scalar conservation laws in one or more spatial dimensions allowing also for source terms of various types is presented. This material is a significant extension of previous work of the first author (Breuß SIAM J. Numer. Anal. 43(3), 970-986 2005). Implicit notions are developed that are centered around a monotonicity criterion. We demonstrate a connection between a numerical scheme and a discrete entropy inequality, which is based on a classical approach by Crandall and Majda. Additionally, three implicit methods are investigated using the developed notions. Next, we conduct a convergence proof which is not based on a classical compactness argument. Finally, the theoretical results are confirmed by various numerical tests.},
  language  = {en}
}
@article{Gaigall2020,
  author    = {Gaigall, Daniel},
  title     = {Hoeffding-Blum-Kiefer-Rosenblatt independence test statistic on partly not identically distributed data},
  series = {Communications in Statistics - Theory and Methods},
  volume    = {51},
  journal   = {Communications in Statistics - Theory and Methods},
  number    = {12},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {1532-415X},
  doi       = {10.1080/03610926.2020.1805767},
  pages     = {4006 -- 4028},
  year      = {2020},
  abstract  = {The established Hoeffding-Blum-Kiefer-Rosenblatt independence test statistic is investigated for partly not identically distributed data. Surprisingly, it turns out that the statistic has the well-known distribution-free limiting null distribution of the classical criterion under standard regularity conditions. An application is testing goodness-of-fit for the regression function in a non parametric random effects meta-regression model, where the consistency is obtained as well. Simulations investigate size and power of the approach for small and moderate sample sizes. A real data example based on clinical trials illustrates how the test can be used in applications.},
  language  = {en}
}
@article{BiewendtBlaschkeBoehnert2020,
  author    = {Biewendt, Marcel and Blaschke, Florian and B{\"o}hnert, Arno},
  title     = {The rebound effect - a systematic review of the current state of affairs},
  series = {European Journal of Economics and Business Studies},
  volume    = {6},
  journal   = {European Journal of Economics and Business Studies},
  number    = {1},
  publisher = {Revistia},
  address   = {London},
  issn      = {2601-8659},
  doi       = {10.26417/134nvy47z},
  pages     = {106 -- 120},
  year      = {2020},
  abstract  = {This publication is intended to present the current state of research on the rebound effect. First, a systematic literature review is carried out to outline (current) scientific models and theories. Research Question 1 follows with a mathematical introduction of the rebound effect, which shows the interdependence of consumer behaviour, technological progress, and interwoven effects for both. Thereupon, the research field is analysed for gaps and limitations by a systematic literature review. To ensure quantitative and qualitative results, a review protocol is used that integrates two different stages and covers all relevant publications released between 2000 and 2019. Accordingly, 392 publications were identified that deal with the rebound effect. These papers were reviewed to obtain relevant information on the two research questions. The literature review shows that research on the rebound effect is not yet comprehensive and focuses mainly on the effect itself rather than solutions to avoid it. Research Question 2 finds that the main gap, and thus the limitations, is that not much research has been published on the actual avoidance of the rebound effect yet. This is a major limitation for practical application by decision-makers and politicians. Therefore, a theoretical analysis was carried out to identify potential theories and ideas to avoid the rebound effect. The most obvious idea to solve this problem is the theory of a Steady-State Economy (SSE), which has been described and reviewed.},
  language  = {en}
}
@article{BiewendtBlaschkeBoehnert2020,
  author    = {Biewendt, Marcel and Blaschke, Florian and B{\"o}hnert, Arno},
  title     = {An evaluation of corporate sustainability in context of the Jevons paradox},
  series = {SocioEconomic Challenges},
  volume    = {4},
  journal   = {SocioEconomic Challenges},
  number    = {3},
  publisher = {ARMG Publishing},
  address   = {Sumy},
  issn      = {2520-6214},
  doi       = {10.21272/sec.4(3).46-65.2020},
  pages     = {46 -- 65},
  year      = {2020},
  abstract  = {The successful implementation and continuous development of sustainable corporate-level solutions is a challenge. These are endeavours in which social, environmental, and financial aspects must be weighed against each other. They can prove difficult to handle and, in some cases, almost unrealistic. Concepts such as green controlling, IT, and manufacturing look promising and are constantly evolving. This paper aims to achieve a better understanding of the field of corporate sustainability (CS). It will evaluate the hypothesis by which Corporate Sustainability thrives, via being efficient, increasing the performance, and raising the value of the input of the enterprises to the resources used. In fact, Corporate Sustainability on the surface could seem to contradict the idea, which supports the understanding that it encourages the reduction of the heavy reliance on the use of natural resources, the overall environmental impact, and above all, their protection. To understand how the contradictory notion of CS came about, in this part of the paper, the emphasis is placed on providing useful insight to this regard. The first part of this paper summarizes various definitions, organizational theories, and measures used for CS and its derivatives like green controlling, IT, and manufacturing. Second, a case study is given that combines the aforementioned sustainability models. In addition to evaluating the hypothesis, the overarching objective of this paper is to demonstrate the use of green controlling, IT, and manufacturing in the corporate sector. Furthermore, this paper outlines the current challenges and possible directions for CS in the future.},
  language  = {en}
}
@article{KezerashviliDachwald2021,
  author    = {Kezerashvili, Roman Ya and Dachwald, Bernd},
  title     = {Preface: Solar sailing: Concepts, technology, and missions II},
  series = {Advances in Space Research},
  volume    = {67},
  journal   = {Advances in Space Research},
  number    = {9},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0273-1177},
  doi       = {10.1016/j.asr.2021.01.037},
  pages     = {2559 -- 2560},
  year      = {2021},
  language  = {en}
}
@article{HagenkampBlankeDoering2021,
  author    = {Hagenkamp, Markus and Blanke, Tobias and D{\"o}ring, Bernd},
  title     = {Thermoelectric building temperature control: a potential assessment},
  series = {International Journal of Energy and Environmental Engineering},
  volume    = {13},
  journal   = {International Journal of Energy and Environmental Engineering},
  publisher = {Springer},
  address   = {Berlin},
  doi       = {10.1007/s40095-021-00424-x},
  pages     = {241 -- 254},
  year      = {2021},
  abstract  = {This study focuses on thermoelectric elements (TEE) as an alternative for room temperature control. TEE are semi-conductor devices that can provide heating and cooling via a heat pump effect without direct noise emissions and no refrigerant use. An efficiency evaluation of the optimal operating mode is carried out for different numbers of TEE, ambient temperatures, and heating loads. The influence of an additional heat recovery unit on system efficiency and an unevenly distributed heating demand are examined. The results show that TEE can provide heat at a coefficient of performance (COP) greater than one especially for small heating demands and high ambient temperatures. The efficiency increases with the number of elements in the system and is subject to economies of scale. The best COP exceeds six at optimal operating conditions. An additional heat recovery unit proves beneficial for low ambient temperatures and systems with few TEE. It makes COPs above one possible at ambient temperatures below 0 ∘C. The effect increases efficiency by maximal 0.81 (from 1.90 to 2.71) at ambient temperature 5 K below room temperature and heating demand Q˙h=100W but is subject to diseconomies of scale. Thermoelectric technology is a valuable option for electricity-based heat supply and can provide cooling and ventilation functions. A careful system design as well as an additional heat recovery unit significantly benefits the performance. This makes TEE superior to direct current heating systems and competitive to heat pumps for small scale applications with focus on avoiding noise and harmful refrigerants.},
  language  = {en}
}
@article{SpietzSproewitzSeefeldtetal.2021,
  author    = {Spietz, Peter and Spr{\"o}witz, Tom and Seefeldt, Patric and Grundmann, Jan Thimo and Jahnke, Rico and Mikschl, Tobias and Mikulz, Eugen and Montenegro, Sergio and Reershemius, Siebo and Renger, Thomas and Ruffer, Michael and Sasaki, Kaname and Sznajder, Maciej and T{\´o}th, Norbert and Ceriotti, Matteo and Dachwald, Bernd and Macdonald, Malcolm and McInnes, Colin and Seboldt, Wolfgang and Quantius, Dominik and Bauer, Waldemar and Wiedemann, Carsten and Grimm, Christian D. and Hercik, David and Ho, Tra-Mi and Lange, Caroline and Schmitz, Nicole},
  title     = {Paths not taken - The Gossamer roadmap's other options},
  series = {Advances in Space Research},
  volume    = {67},
  journal   = {Advances in Space Research},
  number    = {9},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0273-1177},
  doi       = {10.1016/j.asr.2021.01.044},
  pages     = {2912 -- 2956},
  year      = {2021},
  language  = {en}
}
@article{AkimbekovDigelAbdievaetal.2021,
  author    = {Akimbekov, Nuraly S. and Digel, Ilya and Abdieva, Gulzhamal and Ualieva, Perizat and Tastambek, Kuanysh},
  title     = {Lignite biosolubilization and bioconversion by Bacillus sp.: the collation of analytical data},
  series = {Biofuels},
  volume    = {12},
  journal   = {Biofuels},
  number    = {3},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {1759-7277},
  pages     = {247 -- 258},
  year      = {2021},
  abstract  = {The vast metabolic potential of microbes in brown coal (lignite) processing and utilization can greatly contribute to innovative approaches to sustainable production of high-value products from coal. In this study, the multi-faceted and complex coal biosolubilization process by Bacillus sp. RKB 7 isolate from the Kazakhstan coal-mining soil is reported, and the derived products are characterized. Lignite solubilization tests performed for surface and suspension cultures testify to the formation of numerous soluble lignite-derived substances. Almost 24\% of crude lignite (5\% w/v) was solubilized within 14 days under slightly alkaline conditions (pH 8.2). FTIR analysis revealed various functional groups in the obtained biosolubilization products. Analyses of the lignite-derived humic products by UV-Vis and fluorescence spectrometry as well as elemental analysis yielded compatible results indicating the emerging products had a lower molecular weight and degree of aromaticity. Furthermore, XRD and SEM analyses were used to evaluate the biosolubilization processes from mineralogical and microscopic points of view. The findings not only contribute to a deeper understanding of microbe-mineral interactions in coal environments, but also contribute to knowledge of coal biosolubilization and bioconversion with regard to sustainable production of humic substances. The detailed and comprehensive analyses demonstrate the huge biotechnological potential of Bacillus sp. for agricultural productivity and environmental health.},
  language  = {en}
}
@article{HeiligersSchoutetensDachwald2021,
  author    = {Heiligers, Jeannette and Schoutetens, Frederic and Dachwald, Bernd},
  title     = {Photon-sail equilibria in the alpha centauri system},
  series = {Journal of Guidance, Control, and Dynamics},
  volume    = {44},
  journal   = {Journal of Guidance, Control, and Dynamics},
  number    = {5},
  issn      = {1533-3884},
  doi       = {10.2514/1.G005446},
  pages     = {1053 -- 1061},
  year      = {2021},
  language  = {en}
}
@article{Bung2021,
  author    = {Bung, Daniel Bernhard},
  title     = {Extreme flooding in Western Germany: some thoughts on hazards, return periods and risk},
  series = {Hydrolink},
  journal   = {Hydrolink},
  number    = {4},
  publisher = {International Association for Hydro-Environment Engineering and Research (IAHR)},
  address   = {Madrid},
  pages     = {108 -- 113},
  year      = {2021},
  abstract  = {The low-pressure system Bernd involved extreme rainfalls in the Western part of Germany in July 2021, resulting in major floods, severe damages and a tremendous number of casualties. Such extreme events are rare and full flood protection can never be ensured with reasonable financial means. But still, this event must be starting point to reconsider current design concepts. This article aims at sharing some thoughts on potential hazards, the selection of return periods and remaining risk with the focus on Germany.},
  language  = {en}
}
@article{BlankeHagenkampDoeringetal.2021,
  author    = {Blanke, Tobias and Hagenkamp, Markus and D{\"o}ring, Bernd and G{\"o}ttsche, Joachim and Reger, Vitali and Kuhnhenne, Markus},
  title     = {Net-exergetic, hydraulic and thermal optimization of coaxial heat exchangers using fixed flow conditions instead of fixed flow rates},
  series = {Geothermal Energy},
  volume    = {9},
  journal   = {Geothermal Energy},
  number    = {Article number: 19},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {2195-9706},
  doi       = {10.1186/s40517-021-00201-3},
  pages     = {23 Seiten},
  year      = {2021},
  abstract  = {Previous studies optimized the dimensions of coaxial heat exchangers using constant mass fow rates as a boundary condition. They show a thermal optimal circular ring width of nearly zero. Hydraulically optimal is an inner to outer pipe radius ratio of 0.65 for turbulent and 0.68 for laminar fow types. In contrast, in this study, fow conditions in the circular ring are kept constant (a set of fxed Reynolds numbers) during optimization. This approach ensures fxed fow conditions and prevents inappropriately high or low mass fow rates. The optimization is carried out for three objectives: Maximum energy gain, minimum hydraulic efort and eventually optimum net-exergy balance. The optimization changes the inner pipe radius and mass fow rate but not the Reynolds number of the circular ring. The thermal calculations base on Hellstr{\"o}m's borehole resistance and the hydraulic optimization on individually calculated linear loss of head coefcients. Increasing the inner pipe radius results in decreased hydraulic losses in the inner pipe but increased losses in the circular ring. The net-exergy diference is a key performance indicator and combines thermal and hydraulic calculations. It is the difference between thermal exergy fux and hydraulic efort. The Reynolds number in the circular ring is instead of the mass fow rate constant during all optimizations. The result from a thermal perspective is an optimal width of the circular ring of nearly zero. The hydraulically optimal inner pipe radius is 54\% of the outer pipe radius for laminar fow and 60\% for turbulent fow scenarios. Net-exergetic optimization shows a predominant infuence of hydraulic losses, especially for small temperature gains. The exact result depends on the earth's thermal properties and the fow type. Conclusively, coaxial geothermal probes' design should focus on the hydraulic optimum and take the thermal optimum as a secondary criterion due to the dominating hydraulics.},
  language  = {en}
}
@article{CapitainWagnerHummeletal.2021,
  author    = {Capitain, Charlotte and Wagner, Sebastian and Hummel, Joana and Tippk{\"o}tter, Nils},
  title     = {Investigation of C-N Formation Between Catechols and Chitosan for the Formation of a Strong, Novel Adhesive Mimicking Mussel Adhesion},
  series = {Waste and Biomass Valorization},
  volume    = {12},
  journal   = {Waste and Biomass Valorization},
  publisher = {Springer Nature},
  address   = {Cham},
  issn      = {1877-265X},
  doi       = {10.1007/s12649-020-01110-5},
  pages     = {1761 -- 1779},
  year      = {2021},
  language  = {en}
}
@article{GoettenHavermannBraunetal.2021,
  author    = {G{\"o}tten, Falk and Havermann, Marc and Braun, Carsten and Marino, Matthew and Bil, Cees},
  title     = {Aerodynamic Investigations of UAV Sensor Turrets - A Combined Wind-tunnel and CFD Approach},
  series = {SciTech 2021, AIAA SciTech Forum, online, WW, Jan 11-15, 2021},
  journal   = {SciTech 2021, AIAA SciTech Forum, online, WW, Jan 11-15, 2021},
  publisher = {AIAA},
  address   = {Reston, Va.},
  doi       = {10.2514/6.2021-1535},
  pages     = {1 -- 12},
  year      = {2021},
  language  = {en}
}
@article{HunkerGossmannRamanetal.2021,
  author    = {Hunker, Jan L. and Gossmann, Matthias and Raman, Aravind Hariharan and Linder, Peter},
  title     = {Artificial neural networks in cardiac safety assessment: Classification of chemotherapeutic compound effects on hiPSC-derived cardiomyocyte contractility},
  series = {Journal of Pharmacological and Toxicological Methods},
  volume    = {111},
  journal   = {Journal of Pharmacological and Toxicological Methods},
  number    = {Article number 107044},
  publisher = {Elsevier},
  address   = {New York},
  issn      = {1056-8719},
  doi       = {10.1016/j.vascn.2021.107044},
  year      = {2021},
  language  = {en}
}
@article{JablonskiMuenstermannNorketal.2021,
  author    = {Jablonski, Melanie and M{\"u}nstermann, Felix and Nork, Jasmina and Molinnus, Denise and Muschallik, Lukas and Bongaerts, Johannes and Wagner, Torsten and Keusgen, Michael and Siegert, Petra and Sch{\"o}ning, Michael Josef},
  title     = {Capacitive field-effect biosensor applied for the detection of acetoin in alcoholic beverages and fermentation broths},
  series = {physica status solidi (a) applications and materials science},
  volume    = {218},
  journal   = {physica status solidi (a) applications and materials science},
  number    = {13},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.202000765},
  pages     = {7 Seiten},
  year      = {2021},
  abstract  = {An acetoin biosensor based on a capacitive electrolyte-insulator-semiconductor (EIS) structure modified with the enzyme acetoin reductase, also known as butane-2,3-diol dehydrogenase (Bacillus clausii DSM 8716ᵀ), is applied for acetoin detection in beer, red wine, and fermentation broth samples for the first time. The EIS sensor consists of an Al/p-Si/SiO₂/Ta₂O₅ layer structure with immobilized acetoin reductase on top of the Ta₂O₅ transducer layer by means of crosslinking via glutaraldehyde. The unmodified and enzyme-modified sensors are electrochemically characterized by means of leakage current, capacitance-voltage, and constant capacitance methods, respectively.},
  language  = {en}
}
@article{GoettenFingerHavermannetal.2021,
  author    = {G{\"o}tten, Falk and Finger, Felix and Havermann, Marc and Braun, Carsten and Marino, M. and Bil, C.},
  title     = {Full configuration drag estimation of short-to-medium range fixed-wing UAVs and its impact on initial sizing optimization},
  series = {CEAS Aeronautical Journal},
  volume    = {12},
  journal   = {CEAS Aeronautical Journal},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1869-5590 (Online)},
  doi       = {10.1007/s13272-021-00522-w},
  pages     = {589 -- 603},
  year      = {2021},
  abstract  = {The paper presents the derivation of a new equivalent skin friction coefficient for estimating the parasitic drag of short-to-medium range fixed-wing unmanned aircraft. The new coefficient is derived from an aerodynamic analysis of ten different unmanned aircraft used for surveillance, reconnaissance, and search and rescue missions. The aircraft is simulated using a validated unsteady Reynolds-averaged Navier Stokes approach. The UAV's parasitic drag is significantly influenced by the presence of miscellaneous components like fixed landing gears or electro-optical sensor turrets. These components are responsible for almost half of an unmanned aircraft's total parasitic drag. The new equivalent skin friction coefficient accounts for these effects and is significantly higher compared to other aircraft categories. It is used to initially size an unmanned aircraft for a typical reconnaissance mission. The improved parasitic drag estimation yields a much heavier unmanned aircraft when compared to the sizing results using available drag data of manned aircraft.},
  language  = {en}
}
@article{ErpicumCrookstonBombardellietal.2021,
  author    = {Erpicum, Sebastien and Crookston, Brian M. and Bombardelli, Fabian and Bung, Daniel Bernhard and Felder, Stefan and Mulligan, Sean and Oertel, Mario and Palermo, Michele},
  title     = {Hydraulic structures engineering: An evolving science in a changing world},
  series = {Wires Water},
  volume    = {8},
  journal   = {Wires Water},
  number    = {2},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {2049-1948},
  doi       = {10.1002/wat2.1505},
  year      = {2021},
  language  = {en}
}
@article{ButenwegBursiPaolaccietal.2021,
  author    = {Butenweg, Christoph and Bursi, Oreste S. and Paolacci, Fabrizio and Marinković, Marko and Lanese, Igor and Nardin, Chiara and Quinci, Gianluca},
  title     = {Seismic performance of an industrial multi-storey frame structure with process equipment subjected to shake table testing},
  series = {Engineering Structures},
  volume    = {243},
  journal   = {Engineering Structures},
  number    = {15},
  editor    = {Yang, J.},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0141-0296},
  doi       = {10.1016/j.engstruct.2021.112681},
  year      = {2021},
  abstract  = {Past earthquakes demonstrated the high vulnerability of industrial facilities equipped with complex process technologies leading to serious damage of process equipment and multiple and simultaneous release of hazardous substances. Nonetheless, current standards for seismic design of industrial facilities are considered inadequate to guarantee proper safety conditions against exceptional events entailing loss of containment and related consequences. On these premises, the SPIF project -Seismic Performance of Multi-Component Systems in Special Risk Industrial Facilities- was proposed within the framework of the European H2020 SERA funding scheme. In detail, the objective of the SPIF project is the investigation of the seismic behaviour of a representative industrial multi-storey frame structure equipped with complex process components by means of shaking table tests. Along this main vein and in a performance-based design perspective, the issues investigated in depth are the interaction between a primary moment resisting frame (MRF) steel structure and secondary process components that influence the performance of the whole system; and a proper check of floor spectra predictions. The evaluation of experimental data clearly shows a favourable performance of the MRF structure, some weaknesses of local details due to the interaction between floor crossbeams and process components and, finally, the overconservatism of current design standards w.r.t. floor spectra predictions.},
  language  = {en}
}
@article{HacklNacovKammerlohretal.2021,
  author    = {Hackl, Michael and Nacov, Julia and Kammerlohr, Sandra and Staat, Manfred and Buess, Eduard and Leschinger, Tim and M{\"u}ller, Lars P. and Wegmann, Kilian},
  title     = {Intratendinous Strain Variations of the Supraspinatus Tendon Depending on Repair Technique: A Biomechanical Analysis Regarding the Cause of Medial Cuff Failure},
  series = {The American Journal of Sports Medicine},
  volume    = {49},
  journal   = {The American Journal of Sports Medicine},
  number    = {7},
  publisher = {Sage},
  address   = {London},
  issn      = {1552-3365},
  doi       = {10.1177/03635465211006138},
  pages     = {1847 -- 1853},
  year      = {2021},
  language  = {en}
}
@article{TranStaat2021,
  author    = {Tran, Ngoc Trinh and Staat, Manfred},
  title     = {Direct plastic structural design under random strength and random load by chance constrained programming},
  series = {European Journal of Mechanics - A/Solids},
  volume    = {85},
  journal   = {European Journal of Mechanics - A/Solids},
  number    = {Article 104106},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0997-7538},
  doi       = {10.1016/j.euromechsol.2020.104106},
  year      = {2021},
  language  = {en}
}
@article{FaganBitzBjoerkmanBurtscheretal.2021,
  author    = {Fagan, Andrew J. and Bitz, Andreas and Bj{\"o}rkman-Burtscher, Isabella M. and Collins, Christopher M. and Kimbrell, Vera and Raaijmakers, Alexander J. E.},
  title     = {7T MR Safety},
  series = {Journal of Magnetic Resonance Imaging (JMRI)},
  volume    = {53},
  journal   = {Journal of Magnetic Resonance Imaging (JMRI)},
  number    = {2},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1522-2586},
  doi       = {10.1002/jmri.27319},
  pages     = {333 -- 346},
  year      = {2021},
  language  = {en}
}
@article{MeyerGranrathFeyerletal.2021,
  author    = {Meyer, Max-Arno and Granrath, Christian and Feyerl, G{\"u}nter and Richenhagen, Johannes and Kaths, Jakob and Andert, Jakob},
  title     = {Closed-loop platoon simulation with cooperative intelligent transportation systems based on vehicle-to-X communication},
  series = {Simulation Modelling Practice and Theory},
  volume    = {106},
  journal   = {Simulation Modelling Practice and Theory},
  number    = {Art. 102173},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1569-190X},
  doi       = {10.1016/j.simpat.2020.102173},
  year      = {2021},
  language  = {en}
}
@article{SerrorHackHenzeetal.2021,
  author    = {Serror, Martin and Hack, Sacha and Henze, Martin and Schuba, Marko and Wehrle, Klaus},
  title     = {Challenges and Opportunities in Securing the Industrial Internet of Things},
  series = {IEEE Transactions on Industrial Informatics},
  volume    = {17},
  journal   = {IEEE Transactions on Industrial Informatics},
  number    = {5},
  publisher = {IEEE},
  address   = {New York},
  issn      = {1941-0050},
  doi       = {10.1109/TII.2020.3023507},
  pages     = {2985 -- 2996},
  year      = {2021},
  language  = {en}
}
@article{BerneckerBoyerGathmann2021,
  author    = {Bernecker, Andreas and Boyer, Pierre C. and Gathmann, Christina},
  title     = {The Role of Electoral Incentives for Policy Innovation: Evidence from the US Welfare Reform},
  series = {American Economic Journal: Economic Policy},
  volume    = {13},
  journal   = {American Economic Journal: Economic Policy},
  number    = {2},
  publisher = {American Economic Association},
  address   = {Nashville, Tenn.},
  issn      = {1945-774X},
  doi       = {10.1257/pol.20190690},
  pages     = {26 -- 57},
  year      = {2021},
  language  = {en}
}
@article{HugenrothBorchardtRitteretal.2021,
  author    = {Hugenroth, Kristin and Borchardt, Ralf and Ritter, Philine and Groß‑Hardt, Sascha and Meyns, Bart and Verbelen, Tom and Steinseifer, Ulrich and Kaufmann, Tim A. S. and Engelmann, Ulrich M.},
  title     = {Optimizing cerebral perfusion and hemodynamics during cardiopulmonary bypass through cannula design combining in silico, in vitro and in vivo input},
  series = {Scientific Reports},
  volume    = {11},
  journal   = {Scientific Reports},
  number    = {Art. No. 16800},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {2045-2322},
  doi       = {10.1038/s41598-021-96397-2},
  pages     = {1 -- 12},
  year      = {2021},
  abstract  = {Cardiopulmonary bypass (CPB) is a standard technique for cardiac surgery, but comes with the risk of severe neurological complications (e.g. stroke) caused by embolisms and/or reduced cerebral perfusion. We report on an aortic cannula prototype design (optiCAN) with helical outflow and jet-splitting dispersion tip that could reduce the risk of embolic events and restores cerebral perfusion to 97.5\% of physiological flow during CPB in vivo, whereas a commercial curved-tip cannula yields 74.6\%. In further in vitro comparison, pressure loss and hemolysis parameters of optiCAN remain unaffected. Results are reproducibly confirmed in silico for an exemplary human aortic anatomy via computational fluid dynamics (CFD) simulations. Based on CFD simulations, we firstly show that optiCAN design improves aortic root washout, which reduces the risk of thromboembolism. Secondly, we identify regions of the aortic intima with increased risk of plaque release by correlating areas of enhanced plaque growth and high wall shear stresses (WSS). From this we propose another easy-to-manufacture cannula design (opti2CAN) that decreases areas burdened by high WSS, while preserving physiological cerebral flow and favorable hemodynamics. With this novel cannula design, we propose a cannulation option to reduce neurological complications and the prevalence of stroke in high-risk patients after CPB.},
  language  = {en}
}
@article{BrockhausBehbahaniMurisetal.2021,
  author    = {Brockhaus, Moritz K. and Behbahani, Mehdi and Muris, Farina and Jansen, Sebastian V. and Schmitz- Rode, Thomas and Steinseifer, Ulrich and Clauser, Johanna C.},
  title     = {In vitro thrombogenicity testing of pulsatile mechanical circulatory support systems: Design and proof-of-concept},
  series = {Artificial Organs},
  volume    = {45},
  journal   = {Artificial Organs},
  number    = {12},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1525-1594},
  doi       = {10.1111/aor.14046},
  pages     = {1513 -- 1521},
  year      = {2021},
  abstract  = {Thrombogenic complications are a main issue in mechanical circulatory support (MCS). There is no validated in vitro method available to quantitatively assess the thrombogenic performance of pulsatile MCS devices under realistic hemodynamic conditions. The aim of this study is to propose a method to evaluate the thrombogenic potential of new designs without the use of complex in-vivo trials. This study presents a novel in vitro method for reproducible thrombogenicity testing of pulsatile MCS systems using low molecular weight heparinized porcine blood. Blood parameters are continuously measured with full blood thromboelastometry (ROTEM; EXTEM, FIBTEM and a custom-made analysis HEPNATEM). Thrombus formation is optically observed after four hours of testing. The results of three experiments are presented each with two parallel loops. The area of thrombus formation inside the MCS device was reproducible. The implantation of a filter inside the loop catches embolizing thrombi without a measurable increase of platelet activation, allowing conclusions of the place of origin of thrombi inside the device. EXTEM and FIBTEM parameters such as clotting velocity (α) and maximum clot firmness (MCF) show a total decrease by around 6\% with a characteristic kink after 180 minutes. HEPNATEM α and MCF rise within the first 180 minutes indicate a continuously increasing activation level of coagulation. After 180 minutes, the consumption of clotting factors prevails, resulting in a decrease of α and MCF. With the designed mock loop and the presented protocol we are able to identify thrombogenic hot spots inside a pulsatile pump and characterize their thrombogenic potential.},
  language  = {en}
}
@article{LeiseEsserEichenlaubetal.2021,
  author    = {Leise, Philipp and Eßer, Arved and Eichenlaub, Tobias and Schleiffer, Jean-Eric and Altherr, Lena and Rinderknecht, Stephan and Pelz, Peter F.},
  title     = {Sustainable system design of electric powertrains - comparison of optimization methods},
  series = {Engineering Optimization},
  journal   = {Engineering Optimization},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {0305-215X},
  doi       = {10.1080/0305215X.2021.1928660},
  year      = {2021},
  abstract  = {The transition within transportation towards battery electric vehicles can lead to a more sustainable future. To account for the development goal 'climate action' stated by the United Nations, it is mandatory, within the conceptual design phase, to derive energy-efficient system designs. One barrier is the uncertainty of the driving behaviour within the usage phase. This uncertainty is often addressed by using a stochastic synthesis process to derive representative driving cycles and by using cycle-based optimization. To deal with this uncertainty, a new approach based on a stochastic optimization program is presented. This leads to an optimization model that is solved with an exact solver. It is compared to a system design approach based on driving cycles and a genetic algorithm solver. Both approaches are applied to find efficient electric powertrains with fixed-speed and multi-speed transmissions. Hence, the similarities, differences and respective advantages of each optimization procedure are discussed.},
  language  = {en}
}
@article{GrundlachBaumannEngelmann2021,
  author    = {Grundlach, Michael and Baumann, Martin and Engelmann, Ulrich M.},
  title     = {How Multimodal Examinations Can Increase Sustainable Student Gain by Aligning Teaching and Assessment},
  series = {Current Directions in Biomedical Engineering},
  volume    = {7},
  journal   = {Current Directions in Biomedical Engineering},
  number    = {7/2},
  editor    = {D{\"o}ssel, Olaf},
  publisher = {De Gruyter},
  address   = {Berlin},
  isbn      = {2364-5504},
  doi       = {10.1515/cdbme-2021-2019},
  pages     = {73 -- 76},
  year      = {2021},
  abstract  = {Modern industry and multi-discipline projects require highly trained individuals with resilient science and engineering back-grounds. Graduates must be able to agilely apply excellent theoretical knowledge in their subject matter as well as essential practical "hands-on" knowledge of diverse working processes to solve complex problems. To meet these demands, university education follows the concept of Constructive Alignment and thus increasingly adopts the teaching of necessary practical skills to the actual industry requirements and assessment routines. However, a systematic approach to coherently align these three central teaching demands is strangely absent from current university curricula. We demonstrate the feasibility of implementing practical assessments in a regular theory-based examination, thus defining the term "blended assessment". We assessed a course for natural science and engineering students pursuing a career in biomedical engineering, and evaluated the benefit of blended assessment exams for students and lecturers. Our controlled study assessed the physiological background of electrocardiograms (ECGs), the practical measurement of ECG curves, and their interpretation of basic pathologic alterations. To study on long time effects, students have been assessed on the topic twice with a time lag of 6 months. Our findings suggest a significant improvement in student gain with respect to practical skills and theoretical knowledge. The results of the reassessments support these outcomes. From the lecturers' point of view, blended assessment complements practical training courses while keeping organizational effort manageable. We consider blended assessment a viable tool for providing an improved student gain, industry-ready education format that should be evaluated and established further to prepare university graduates optimally for their future careers.},
  language  = {en}
}
@article{EngemannCoenenDawaretal.2021,
  author    = {Engemann, Heiko and C{\"o}nen, Patrick and Dawar, Harshal and Du, Shengzhi and Kallweit, Stephan},
  title     = {A robot-assisted large-scale inspection of wind turbine blades in manufacturing using an autonomous mobile manipulator},
  series = {Applied Sciences},
  volume    = {11},
  journal   = {Applied Sciences},
  number    = {19},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2076-3417},
  doi       = {10.3390/app11199271},
  pages     = {1 -- 22},
  year      = {2021},
  abstract  = {Wind energy represents the dominant share of renewable energies. The rotor blades of a wind turbine are typically made from composite material, which withstands high forces during rotation. The huge dimensions of the rotor blades complicate the inspection processes in manufacturing. The automation of inspection processes has a great potential to increase the overall productivity and to create a consistent reliable database for each individual rotor blade. The focus of this paper is set on the process of rotor blade inspection automation by utilizing an autonomous mobile manipulator. The main innovations include a novel path planning strategy for zone-based navigation, which enables an intuitive right-hand or left-hand driving behavior in a shared human-robot workspace. In addition, we introduce a new method for surface orthogonal motion planning in connection with large-scale structures. An overall execution strategy controls the navigation and manipulation processes of the long-running inspection task. The implemented concepts are evaluated in simulation and applied in a real-use case including the tip of a rotor blade form.},
  language  = {en}
}
@article{OliveiraMolinnusBegingetal.2021,
  author    = {Oliveira, Danilo A. and Molinnus, Denise and Beging, Stefan and Siqueira Jr, Jos{\´e} R. and Sch{\"o}ning, Michael Josef},
  title     = {Biosensor Based on Self-Assembled Films of Graphene Oxide and Polyaniline Using a Field-Effect Device Platform},
  series = {physica status solidi (a) applications and materials science},
  volume    = {218},
  journal   = {physica status solidi (a) applications and materials science},
  number    = {13},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.202000747},
  pages     = {1 -- 9},
  year      = {2021},
  abstract  = {A new functionalization method to modify capacitive electrolyte-insulator-semiconductor (EIS) structures with nanofilms is presented. Layers of polyallylamine hydrochloride (PAH) and graphene oxide (GO) with the compound polyaniline:poly(2-acrylamido-2-methyl-1-propanesulfonic acid) (PANI:PAAMPSA) are deposited onto a p-Si/SiO2 chip using the layer-by-layer technique (LbL). Two different enzymes (urease and penicillinase) are separately immobilized on top of a five-bilayer stack of the PAH:GO/PANI:PAAMPSA-modified EIS chip, forming a biosensor for detection of urea and penicillin, respectively. Electrochemical characterization is performed by constant capacitance (ConCap) measurements, and the film morphology is characterized by atomic force microscopy (AFM) and scanning electron microscopy (SEM). An increase in the average sensitivity of the modified biosensors (EIS-nanofilm-enzyme) of around 15\% is found in relation to sensors, only carrying the enzyme but without the nanofilm (EIS-enzyme). In this sense, the nanofilm acts as a stable bioreceptor onto the EIS chip improving the output signal in terms of sensitivity and stability.},
  language  = {en}
}
@article{WeldenNagamineKomesuWagneretal.2021,
  author    = {Welden, Rene and Nagamine Komesu, Cindy A. and Wagner, Patrick H. and Sch{\"o}ning, Michael Josef and Wagner, Torsten},
  title     = {Photoelectrochemical enzymatic penicillin biosensor: A proof-of-concept experiment},
  series = {Electrochemical Science Advances},
  volume    = {2},
  journal   = {Electrochemical Science Advances},
  number    = {4},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {2698-5977},
  doi       = {10.1002/elsa.202100131},
  pages     = {1 -- 5},
  year      = {2021},
  abstract  = {Photoelectrochemical (PEC) biosensors are a rather novel type of biosensors thatutilizelighttoprovideinformationaboutthecompositionofananalyte,enablinglight-controlled multi-analyte measurements. For enzymatic PEC biosensors,amperometric detection principles are already known in the literature. In con-trast, there is only a little information on H+-ion sensitive PEC biosensors. Inthis work, we demonstrate the detection of H+ions emerged by H+-generatingenzymes, exemplarily demonstrated with penicillinase as a model enzyme on atitanium dioxide photoanode. First, we describe the pH sensitivity of the sensorand study possible photoelectrocatalytic reactions with penicillin. Second, weshow the enzymatic PEC detection of penicillin.},
  language  = {en}
}
@article{RichterBraunsteinStaeudleetal.2021,
  author    = {Richter, Charlotte and Braunstein, Bjoern and Staeudle, Benjamin and Attias, Julia and Suess, Alexander and Weber, Tobias and Mileva, Katya N. and Rittweger, Joern and Green, David A. and Albracht, Kirsten},
  title     = {Contractile behavior of the gastrocnemius medialis muscle during running in simulated hypogravity},
  series = {npj Microgravity},
  volume    = {7},
  journal   = {npj Microgravity},
  number    = {Article number: 32},
  publisher = {Springer Nature},
  address   = {New York},
  issn      = {2373-8065},
  doi       = {10.1038/s41526-021-00155-7},
  pages     = {7 Seiten},
  year      = {2021},
  abstract  = {Vigorous exercise countermeasures in microgravity can largely attenuate muscular degeneration, albeit the extent of applied loading is key for the extent of muscle wasting. Running on the International Space Station is usually performed with maximum loads of 70\% body weight (0.7 g). However, it has not been investigated how the reduced musculoskeletal loading affects muscle and series elastic element dynamics, and thereby force and power generation. Therefore, this study examined the effects of running on the vertical treadmill facility, a ground-based analog, at simulated 0.7 g on gastrocnemius medialis contractile behavior. The results reveal that fascicle-series elastic element behavior differs between simulated hypogravity and 1 g running. Whilst shorter peak series elastic element lengths at simulated 0.7 g appear to be the result of lower muscular and gravitational forces acting on it, increased fascicle lengths and decreased velocities could not be anticipated, but may inform the development of optimized running training in hypogravity. However, whether the alterations in contractile behavior precipitate musculoskeletal degeneration warrants further study.},
  language  = {en}
}
@article{HeinkeKnickerAlbracht2021,
  author    = {Heinke, Lars N. and Knicker, Axel J. and Albracht, Kirsten},
  title     = {Test-retest reliability of the internal shoulder rotator muscles' stretch reflex in healthy men},
  series = {Journal of Electromyography and Kinesiology},
  volume    = {62},
  journal   = {Journal of Electromyography and Kinesiology},
  number    = {Article 102611},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1050-6411},
  doi       = {10.1016/j.jelekin.2021.102611},
  year      = {2021},
  abstract  = {Until now the reproducibility of the short latency stretch reflex of the internal rotator muscles of the glenohumeral joint has not been identified. Twenty-three healthy male participants performed three sets of external shoulder rotation stretches with various pre-activation levels on two different dates of measurement to assess test-retest reliability. All stretches were applied with a dynamometer acceleration of 104°/s2 and a velocity of 150°/s. Electromyographical response was measured via surface EMG. Reflex latencies showed a pre-activation effect (ƞ2 = 0,355). ICC ranged from 0,735 to 0,909 indicating an overall "good" relative reliability. SRD 95\% lay between ±7,0 to ±12,3 ms.. The reflex gain showed overall poor test-retest reproducibility. The chosen methodological approach presented a suitable test protocol for shoulder muscles stretch reflex latency evaluation. A proof-of-concept study to validate the presented methodical approach in shoulder involvement including subjects with clinically relevant conditions is recommended.},
  language  = {en}
}
@article{HeelDiktaBraekers2021,
  author    = {Heel, Mareike van and Dikta, Gerhard and Braekers, Roel},
  title     = {Bootstrap based goodness‑of‑fit tests for binary multivariate regression models},
  series = {Journal of the Korean Statistical Society},
  volume    = {51},
  journal   = {Journal of the Korean Statistical Society},
  publisher = {Springer Nature},
  address   = {Singapur},
  issn      = {2005-2863 (Online)},
  doi       = {10.1007/s42952-021-00142-4},
  pages     = {28 Seiten},
  year      = {2021},
  abstract  = {We consider a binary multivariate regression model where the conditional expectation of a binary variable given a higher-dimensional input variable belongs to a parametric family. Based on this, we introduce a model-based bootstrap (MBB) for higher-dimensional input variables. This test can be used to check whether a sequence of independent and identically distributed observations belongs to such a parametric family. The approach is based on the empirical residual process introduced by Stute (Ann Statist 25:613-641, 1997). In contrast to Stute and Zhu's approach (2002) Stute \& Zhu (Scandinavian J Statist 29:535-545, 2002), a transformation is not required. Thus, any problems associated with non-parametric regression estimation are avoided. As a result, the MBB method is much easier for users to implement. To illustrate the power of the MBB based tests, a small simulation study is performed. Compared to the approach of Stute \& Zhu (Scandinavian J Statist 29:535-545, 2002), the simulations indicate a slightly improved power of the MBB based method. Finally, both methods are applied to a real data set.},
  language  = {en}
}
@article{BraunChengDoweyetal.2021,
  author    = {Braun, Sebastian and Cheng, Chi-Tsun and Dowey, Steve and Wollert, J{\"o}rg},
  title     = {Performance evaluation of skill-based order-assignment in production environments with multi-agent systems},
  series = {IEEE Journal of Emerging and Selected Topics in Industrial Electronics},
  journal   = {IEEE Journal of Emerging and Selected Topics in Industrial Electronics},
  number    = {Early Access},
  publisher = {IEEE},
  address   = {New York},
  issn      = {2687-9735},
  doi       = {10.1109/JESTIE.2021.3108524},
  year      = {2021},
  abstract  = {The fourth industrial revolution introduces disruptive technologies to production environments. One of these technologies are multi-agent systems (MASs), where agents virtualize machines. However, the agent's actual performances in production environments can hardly be estimated as most research has been focusing on isolated projects and specific scenarios. We address this gap by implementing a highly connected and configurable reference model with quantifiable key performance indicators (KPIs) for production scheduling and routing in single-piece workflows. Furthermore, we propose an algorithm to optimize the search of extrema in highly connected distributed systems. The benefits, limits, and drawbacks of MASs and their performances are evaluated extensively by event-based simulations against the introduced model, which acts as a benchmark. Even though the performance of the proposed MAS is, on average, slightly lower than the reference system, the increased flexibility allows it to find new solutions and deliver improved factory-planning outcomes. Our MAS shows an emerging behavior by using flexible production techniques to correct errors and compensate for bottlenecks. This increased flexibility offers substantial improvement potential. The general model in this paper allows the transfer of the results to estimate real systems or other models.},
  language  = {en}
}
@article{JildehWagnerSchoening2021,
  author    = {Jildeh, Zaid B. and Wagner, Patrick H. and Sch{\"o}ning, Michael Josef},
  title     = {Sterilization of Objects, Products, and Packaging Surfaces and Their Characterization in Different Fields of Industry: The Status in 2020},
  series = {physica status solidi (a) applications and materials science},
  volume    = {218},
  journal   = {physica status solidi (a) applications and materials science},
  number    = {13},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.202000732},
  pages     = {27 Seiten},
  year      = {2021},
  abstract  = {The treatment method to deactivate viable microorganisms from objects or products is termed sterilization. There are multiple forms of sterilization, each intended to be applied for a specific target, which depends on—but not limited to—the thermal, physical, and chemical stability of that target. Herein, an overview on the currently used sterilization processes in the global market is provided. Different sterilization techniques are grouped under a category that describes the method of treatment: radiation (gamma, electron beam, X-ray, and ultraviolet), thermal (dry and moist heat), and chemical (ethylene oxide, ozone, chlorine dioxide, and hydrogen peroxide). For each sterilization process, the typical process parameters as defined by regulations and the mode of antimicrobial activity are summarized. Finally, the recommended microorganisms that are used as biological indicators to validate sterilization processes in accordance with the rules that are established by various regulatory agencies are summarized.},
  language  = {en}
}
@article{MolinnusDrinicIkenetal.2021,
  author    = {Molinnus, Denise and Drinic, Aleksander and Iken, Heiko and Kr{\"o}ger, Nadja and Zinser, Max and Smeets, Ralf and K{\"o}pf, Marius and Kopp, Alexander and Sch{\"o}ning, Michael Josef},
  title     = {Towards a flexible electrochemical biosensor fabricated from biocompatible Bombyx mori silk},
  series = {Biosensors and Bioelectronics},
  volume    = {183},
  journal   = {Biosensors and Bioelectronics},
  number    = {Art. 113204},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0956-5663},
  doi       = {10.1016/j.bios.2021.113204},
  year      = {2021},
  language  = {en}
}
@article{YoshinobuSchoening2021,
  author    = {Yoshinobu, Tatsuo and Sch{\"o}ning, Michael Josef},
  title     = {Light-addressable potentiometric sensors (LAPS) for cell monitoring and biosensing},
  series = {Current Opinion in Electrochemistry},
  journal   = {Current Opinion in Electrochemistry},
  number    = {In Press, Journal Pre-proof},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2451-9103},
  doi       = {10.1016/j.coelec.2021.100727},
  year      = {2021},
  language  = {en}
}
@article{Maurischat2021,
  author    = {Maurischat, Andreas},
  title     = {Algebraic independence of the Carlitz period and its hyperderivatives},
  pages     = {1 -- 12},
  year      = {2021},
  language  = {en}
}
@article{WertIkenSchoeningetal.2021,
  author    = {Wert, Stefan and Iken, Heiko and Sch{\"o}ning, Michael Josef and Matysik, Frank-Michael},
  title     = {Development of a temperature-pulse enhanced electrochemical glucose biosensor and characterization of its stability via scanning electrochemical microscopy},
  series = {Electroanalysis},
  journal   = {Electroanalysis},
  number    = {Early View},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-4109},
  doi       = {10.1002/elan.202100089},
  year      = {2021},
  abstract  = {Glucose oxidase (GOx) is an enzyme frequently used in glucose biosensors. As increased temperatures can enhance the performance of electrochemical sensors, we investigated the impact of temperature pulses on GOx that was drop-coated on flattened Pt microwires. The wires were heated by an alternating current. The sensitivity towards glucose and the temperature stability of GOx was investigated by amperometry. An up to 22-fold increase of sensitivity was observed. Spatially resolved enzyme activity changes were investigated via scanning electrochemical microscopy. The application of short (<100 ms) heat pulses was associated with less thermal inactivation of the immobilized GOx than long-term heating.},
  language  = {en}
}
@article{LowisFergusonPaulssenetal.2021,
  author    = {Lowis, Carsten and Ferguson, Simon and Paulßen, Elisabeth and Hoehr, Cornelia},
  title     = {Improved Sc-44 production in a siphon-style liquid target on a medical cyclotron},
  series = {Applied Radiation and Isotopes},
  volume    = {172},
  journal   = {Applied Radiation and Isotopes},
  number    = {Art. 109675},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0969-8043},
  doi       = {10.1016/j.apradiso.2021.109675},
  year      = {2021},
  language  = {en}
}
@article{WaldvogelRitzmannFreyleretal.2021,
  author    = {Waldvogel, Janice and Ritzmann, Ramona and Freyler, Kathrin and Helm, Michael and Monti, Elena and Albracht, Kirsten and St{\"a}udle, Benjamin and Gollhofer, Albert and Narici, Marco},
  title     = {The Anticipation of Gravity in Human Ballistic Movement},
  series = {Frontiers in Physiology},
  journal   = {Frontiers in Physiology},
  publisher = {Frontiers},
  address   = {Lausanne},
  issn      = {1664-042X},
  doi       = {10.3389/fphys.2021.614060},
  year      = {2021},
  abstract  = {Stretch-shortening type actions are characterized by lengthening of the pre-activated muscle-tendon unit (MTU) in the eccentric phase immediately followed by muscle shortening. Under 1 g, pre-activity before and muscle activity after ground contact, scale muscle stiffness, which is crucial for the recoil properties of the MTU in the subsequent push-off. This study aimed to examine the neuro-mechanical coupling of the stretch-shortening cycle in response to gravity levels ranging from 0.1 to 2 g. During parabolic flights, 17 subjects performed drop jumps while electromyography (EMG) of the lower limb muscles was combined with ultrasound images of the gastrocnemius medialis, 2D kinematics and kinetics to depict changes in energy management and performance. Neuro-mechanical coupling in 1 g was characterized by high magnitudes of pre-activity and eccentric muscle activity allowing an isometric muscle behavior during ground contact. EMG during pre-activity and the concentric phase systematically increased from 0.1 to 1 g. Below 1 g the EMG in the eccentric phase was diminished, leading to muscle lengthening and reduced MTU stretches. Kinetic energy at take-off and performance were decreased compared to 1 g. Above 1 g, reduced EMG in the eccentric phase was accompanied by large MTU and muscle stretch, increased joint flexion amplitudes, energy loss and reduced performance. The energy outcome function established by linear mixed model reveals that the central nervous system regulates the extensor muscles phase- and load-specifically. In conclusion, neuro-mechanical coupling appears to be optimized in 1 g. Below 1 g, the energy outcome is compromised by reduced muscle stiffness. Above 1 g, loading progressively induces muscle lengthening, thus facilitating energy dissipation.},
  language  = {en}
}
@article{BohndickBosseJaenschetal.2021,
  author    = {Bohndick, Carla and Bosse, Elke and J{\"a}nsch, Vanessa K. and Barnat, Miriam},
  title     = {How different diversity factors affect the perception of first-year requirements in higher education},
  series = {Frontline Learning Research},
  volume    = {9},
  journal   = {Frontline Learning Research},
  number    = {2},
  publisher = {EARLI},
  issn      = {2295-3159},
  doi       = {10.14786/flr.v9i2.667},
  pages     = {78 -- 95},
  year      = {2021},
  abstract  = {In the light of growing university entry rates, higher education institutions not only serve larger numbers of students, but also seek to meet first-year students' ever more diverse needs. Yet to inform universities how to support the transition to higher education, research only offers limited insights. Current studies tend to either focus on the individual factors that affect student success or they highlight students' social background and their educational biography in order to examine the achievement of selected, non-traditional groups of students. Both lines of research appear to lack integration and often fail to take organisational diversity into account, such as different types of higher education institutions or degree programmes. For a more comprehensive understanding of student diversity, the present study includes individual, social and organisational factors. To gain insights into their role for the transition to higher education, we examine how the different factors affect the students' perception of the formal and informal requirements of the first year as more or less difficult to cope with. As the perceived requirements result from both the characteristics of the students and the institutional context, they allow to investigate transition at the interface of the micro and the meso level of higher education. Latent profile analyses revealed that there are no profiles with complex patterns of perception of the first-year requirements, but the identified groups rather differ in the overall level of perceived challenges. Moreover, SEM indicates that the differences in the perception largely depend on the individual factors self-efficacy and volition.},
  language  = {en}
}
@article{HugenrothNeidlinEngelmannetal.2021,
  author    = {Hugenroth, Kristin and Neidlin, Michael and Engelmann, Ulrich M. and Kaufmann, Tim A. S. and Steinseifer, Ulrich and Heilmann, Torsten},
  title     = {Tipless Transseptal Cannula Concept Combines Improved Hemodynamic Properties and Risk-Reduced Placement: an In Silico Proof-of-Concept},
  series = {Artificial Organs},
  journal   = {Artificial Organs},
  number    = {Accepted Article},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1525-1594},
  doi       = {10.1111/aor.13964},
  year      = {2021},
  language  = {en}
}
@article{GivanoudiCornelisRasschaertetal.2021,
  author    = {Givanoudi, Stella and Cornelis, Peter and Rasschaert, Geertrui and Wackers, Gideon and Iken, Heiko and Rolka, David and Yongabi, Derick and Robbens, Johan and Sch{\"o}ning, Michael Josef and Heyndrickx, Marc and Wagner, Patrick},
  title     = {Selective Campylobacter detection and quantification in poultry: A sensor tool for detecting the cause of a common zoonosis at its source},
  series = {Sensors and Actuators B: Chemical},
  journal   = {Sensors and Actuators B: Chemical},
  number    = {In Press, Journal Pre-proof},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2021.129484},
  pages     = {Article 129484},
  year      = {2021},
  language  = {en}
}
@article{RichterBraunsteinStaeudleetal.2021,
  author    = {Richter, Charlotte and Braunstein, Bj{\"o}rn and St{\"a}udle, Benjamin and Attias, Julia and S{\"u}ss, Alexander and Weber, Tobias and Mileva, Katya N. and Rittweger, J{\"o}rn and Green, David A. and Albracht, Kirsten},
  title     = {Gastrocnemius medialis contractile behavior during running differs between simulated Lunar and Martian gravities},
  series = {Scientific reports},
  volume    = {11},
  journal   = {Scientific reports},
  number    = {Article number: 22555},
  publisher = {Springer Nature},
  address   = {London},
  issn      = {2045-2322},
  doi       = {10.1038/s41598-021-00527-9},
  pages     = {13 Seiten},
  year      = {2021},
  abstract  = {The international partnership of space agencies has agreed to proceed forward to the Moon sustainably. Activities on the Lunar surface (0.16 g) will allow crewmembers to advance the exploration skills needed when expanding human presence to Mars (0.38 g). Whilst data from actual hypogravity activities are limited to the Apollo missions, simulation studies have indicated that ground reaction forces, mechanical work, muscle activation, and joint angles decrease with declining gravity level. However, these alterations in locomotion biomechanics do not necessarily scale to the gravity level, the reduction in gastrocnemius medialis activation even appears to level off around 0.2 g, while muscle activation pattern remains similar. Thus, it is difficult to predict whether gastrocnemius medialis contractile behavior during running on Moon will basically be the same as on Mars. Therefore, this study investigated lower limb joint kinematics and gastrocnemius medialis behavior during running at 1 g, simulated Martian gravity, and simulated Lunar gravity on the vertical treadmill facility. The results indicate that hypogravity-induced alterations in joint kinematics and contractile behavior still persist between simulated running on the Moon and Mars. This contrasts with the concept of a ceiling effect and should be carefully considered when evaluating exercise prescriptions and the transferability of locomotion practiced in Lunar gravity to Martian gravity.},
  language  = {en}
}
@article{WerkhausenWillwacherAlbracht2021,
  author    = {Werkhausen, Amelie and Willwacher, Steffen and Albracht, Kirsten},
  title     = {Medial gastrocnemius muscle fascicles shorten throughout stance during sprint acceleration},
  series = {Scandinavian Journal of Medicine \& Science in Sports},
  volume    = {31},
  journal   = {Scandinavian Journal of Medicine \& Science in Sports},
  number    = {7},
  publisher = {Wiley-Blackwell},
  address   = {Oxford},
  issn      = {0905-7188 (Druckausgabe)},
  doi       = {10.1111/sms.13956},
  pages     = {1471 -- 1480},
  year      = {2021},
  abstract  = {The compliant nature of distal limb muscle-tendon units is traditionally considered suboptimal in explosive movements when positive joint work is required. However, during accelerative running, ankle joint net mechanical work is positive. Therefore, this study aims to investigate how plantar flexor muscle-tendon behavior is modulated during fast accelerations. Eleven female sprinters performed maximum sprint accelerations from starting blocks, while gastrocnemius muscle fascicle lengths were estimated using ultrasonography. We combined motion analysis and ground reaction force measurements to assess lower limb joint kinematics and kinetics, and to estimate gastrocnemius muscle-tendon unit length during the first two acceleration steps. Outcome variables were resampled to the stance phase and averaged across three to five trials. Relevant scalars were extracted and analyzed using one-sample and two-sample t-tests, and vector trajectories were compared using statistical parametric mapping. We found that an uncoupling of muscle fascicle behavior from muscle-tendon unit behavior is effectively used to produce net positive mechanical work at the joint during maximum sprint acceleration. Muscle fascicles shortened throughout the first and second steps, while shortening occurred earlier during the first step, where negative joint work was lower compared with the second step. Elastic strain energy may be stored during dorsiflexion after touchdown since fascicles did not lengthen at the same time to dissipate energy. Thus, net positive work generation is accommodated by the reuse of elastic strain energy along with positive gastrocnemius fascicle work. Our results show a mechanism of how muscles with high in-series compliance can contribute to net positive joint work.},
  language  = {en}
}
@article{MontiWaldvogelRitzmannetal.2021,
  author    = {Monti, Elena and Waldvogel, Janice and Ritzmann, Ramona and Freyler, Kathrin and Albracht, Kirsten and Helm, Michael and De Cesare, Niccol{\`o} and Pavan, Piero and Reggiani, Carlo and Gollhofer, Albert and Narici, Marco Vincenzo},
  title     = {Muscle in variable gravity: "I do not know where I am, but I know what to do"},
  series = {Frontiers in Physiology},
  volume    = {12},
  journal   = {Frontiers in Physiology},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1664-042X},
  doi       = {10.3389/fphys.2021.714655},
  pages     = {19 Seiten},
  year      = {2021},
  abstract  = {Performing tasks, such as running and jumping, requires activation of the agonist and antagonist muscles before (motor unit pre-activation) and during movement performance (Santello and Mcdonagh, 1998). A well-timed and regulated muscle activation elicits a stretch-shortening cycle (SSC) response, naturally occurring in bouncing movements (Ishikawa and Komi, 2004; Taube et al., 2012). By definition, the SSC describes the stretching of a pre-activated muscle-tendon complex immediately followed by a muscle shortening in the concentric push-off phase (Komi, 1984). Given the importance of SSC actions for human movement, it is not surprising that many studies investigated the biomechanics of this phenomenon; in particular, drop jumps (DJs) represent a good paradigm to study muscle fascicle and tendon behavior in ballistic movements involving the SSC. Within a DJ, three main phases [pre-activation, braking, and push-off (PO; Komi, 2000)] have been recognized and extensively studied in common and challenging conditions, such as changes in load, falling height, or simulated hypo-gravity (Avela et al., 1994; Arampatzis et al., 2001; Fukashiro et al., 2005; Ishikawa et al., 2005; Sousa et al., 2007; Ritzmann et al., 2016; Helm et al., 2020). These studies show that the timing and amount of triceps-surae muscle-tendon unit pre-activation in DJs are differentially regulated based on the load applied to the muscle, being optimal in normal "Earth" gravity conditions (Avela et al., 1994), but decreased in simulated hypo-gravity, hyper-gravity (Avela et al., 1994; Ritzmann et al., 2016), or unknown conditions (i.e., unknown falling heights; Helm et al., 2020). Some authors indicated that, when falling from heights different from the optimal one [defined as the drop height giving a maximum DJ performance indicated as peak ground reaction force (GRF) or jump high], electromyographic (EMG) activity of the plantar flexors increases from lower than optimal to higher than optimal heights (Ishikawa and Komi, 2004; Sousa et al., 2007). These findings highlight the ability of the central nervous system to regulate the timing and amount of pre-activation according to different jumping conditions, thus regulating muscle fascicle length, tendon and joint stiffness as well as position, in order to safely land on the ground and quickly re-bounce. Similarly, to pre-activation, also in the braking phase, the plantar flexors are differentially regulated. In optimal height (i.e., load) jumping conditions, gastrocnemius medialis (GM) fascicles shorten at early ground contact (possibly due to the intervention of the stretch reflex; Gollhofer et al., 1992) and behave quasi-isometrically in the late braking phase, enabling tendon elongation, and storage of elastic energy (Gollhofer et al., 1992; Fukashiro et al., 2005; Sousa et al., 2007). When increasing the falling height (augmenting the impact GRF), the quasi-isometric behavior of fascicles disappears, and fast fascicle lengthening occurs (Ishikawa et al., 2005; Sousa et al., 2007). In the third and last PO phase, fascicles shorten and the tendon releases the elastic energy previously stored. Bobbert et al. (1987) reported no influence of jumping height on the work done and on the net vertical impulse assessed during PO; this observation suggests that, despite an optimal DJ performance might be achieved only in specific conditions (falling heights, loads), the central nervous system seems to be able to regulate muscle behavior in order to effectively perform the required task also in challenging situations. Although the regulation of triceps-surae muscle-tendon unit in DJs has been extensively investigated, very few studies focused on sarcomeres behavior during the performance of this SSC movement (Kurokawa et al., 2003; Fukashiro et al., 2005, 2006). Sarcomeres represent muscle contractile units and are known to express different amounts of force depending on their length (Gordon et al., 1966; Walker and Schrodt, 1974); thus, understanding the time course of their responses during DJs is fundamental to gain further insights into muscle force-generating capacity. In vivo measurement of sarcomere length in humans has been so far been performed only in static positions and under highly controlled experimental conditions (Llewellyn et al., 2008; Sanchez et al., 2015). Instead, human sarcomere length estimation (achieved by dividing GM measured fascicle length for a fixed sarcomere number) in dynamic contractions provided an indirect measure of sarcomere operating range during squat jump, countermovement jump, and DJ (Fukashiro et al., 2005, 2006; Kurokawa et al., 2003). The results of these studies showed that sarcomeres operate in the ascending limb of their length-tension (L-T) relationship in all types of jumps, and particularly so in DJ. However, most of the available observations on sarcomere and muscle fascicle behavior were made in condition of constant gravity. Thus, in order to understand how sarcomere and muscle fascicle length are regulated in variable gravity conditions, we performed experiments in a parabolic flight, involving variable gravity levels, ranging from about zero-g to about double the Earth's gravity (1 g; Waldvogel et al., 2021). Specifically, the aims of the present study were as follows: 1. To investigate the ability of the neuromuscular system in regulating fascicle length in response to conditions of variable gravity. 2. To estimate sarcomere operative length in the different DJ phases, in order to calculate its theoretical force production and its possible modulation in conditions of variable gravity. We hypothesized that muscle fascicles would be differentially regulated in different gravity conditions compared to 1 g, particularly in anticipation of landing and re-bouncing in unknown gravity levels. In addition, we hypothesized that sarcomeres would operate in the upper part of the ascending limb of their L-T relationship, possibly lengthening during the braking phase (especially in hyper-gravity) while operating quasi-isometrically in 1 g.},
  language  = {en}
}
@article{StaeudleSeynnesLapsetal.2021,
  author    = {St{\"a}udle, Benjamin and Seynnes, Olivier and Laps, Guido and G{\"o}ll, Fabian and Br{\"u}ggemann, Gert-Peter and Albracht, Kirsten},
  title     = {Recovery from achilles tendon repair: a combination of Postsurgery Outcomes and Insufficient remodeling of muscle and tendon},
  series = {Medicine \& Science in Sports \& Exercise},
  volume    = {53},
  journal   = {Medicine \& Science in Sports \& Exercise},
  number    = {7},
  publisher = {American College of Sports Medicine},
  address   = {Philadelphia, Pa.},
  issn      = {1530-0315},
  doi       = {10.1249/MSS.0000000000002592},
  pages     = {1356 -- 1366},
  year      = {2021},
  abstract  = {Achilles tendon rupture (ATR) patients have persistent functional deficits in the triceps surae muscle-tendon unit (MTU). The complex remodeling of the MTU accompanying these deficits remains poorly understood. The purpose of the present study was to associate in vivo and in silico data to investigate the relations between changes inMTU properties and strength deficits inATR patients. Methods: Elevenmale subjects who had undergone surgical repair of complete unilateral ATR were examined 4.6 ± 2.0 (mean ± SD) yr after rupture. Gastrocnemius medialis (GM) tendon stiffness, morphology, and muscle architecture were determined using ultrasonography. The force-length relation of the plantar flexor muscles was assessed at five ankle joint angles. In addition, simulations (OpenSim) of the GM MTU force-length properties were performed with various iterations of MTU properties found between the unaffected and the affected side. Results: The affected side of the patients displayed a longer, larger, and stiffer GM tendon (13\% ± 10\%, 105\% ± 28\%, and 54\% ± 24\%, respectively) compared with the unaffected side. The GM muscle fascicles of the affected side were shorter (32\% ± 12\%) and with greater pennation angles (31\% ± 26\%). A mean deficit in plantarflexion moment of 31\% ± 10\% was measured. Simulations indicate that pairing an intact muscle with a longer tendon shifts the optimal angular range of peak force outside physiological angular ranges, whereas the shorter muscle fascicles and tendon stiffening seen in the affected side decrease this shift, albeit incompletely. Conclusions: These results suggest that the substantial changes in MTU properties found in ATR patients may partly result from compensatory remodeling, although this process appears insufficient to fully restore muscle function.},
  language  = {en}
}