@article{MiyamotoSatoAbeetal.2016,
  author    = {Miyamoto, Ko-Ichiro and Sato, Takuya and Abe, Minami and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo},
  title     = {Light-addressable potentiometric sensor as a sensing element in plug-based microfluidic devices},
  series = {Micromachines},
  volume    = {7},
  journal   = {Micromachines},
  number    = {7},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2072-666X},
  doi       = {10.3390/mi7070111},
  pages     = {111},
  year      = {2016},
  abstract  = {A plug-based microfluidic system based on the principle of the light-addressable potentiometric sensor (LAPS) is proposed. The LAPS is a semiconductor-based chemical sensor, which has a free addressability of the measurement point on the sensing surface. By combining a microfluidic device and LAPS, ion sensing can be performed anywhere inside the microfluidic channel. In this study, the sample solution to be measured was introduced into the channel in a form of a plug with a volume in the range of microliters. Taking advantage of the light-addressability, the position of the plug could be monitored and pneumatically controlled. With the developed system, the pH value of a plug with a volume down to 400 nL could be measured. As an example of plug-based operation, two plugs were merged in the channel, and the pH change was detected by differential measurement.},
  language  = {en}
}
@inproceedings{BaeckerKochGeigeretal.2016,
  author    = {B{\"a}cker, Matthias and Koch, C. and Geiger, F. and Eber, F. and Gliemann, H. and Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {A New Class of Biosensors Based on Tobacco Mosaic Virus and Coat Proteins as Enzyme Nanocarrier},
  series = {Procedia Engineering},
  volume    = {Vol. 168},
  booktitle = {Procedia Engineering},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2016.11.228},
  pages     = {618 -- 621},
  year      = {2016},
  language  = {en}
}
@inproceedings{PoghossianBronderSchejaetal.2016,
  author    = {Poghossian, Arshak and Bronder, Thomas and Scheja, S. and Wu, Chunsheng and Metzger-Boddien, C. and Keusgen, M. and Sch{\"o}ning, Michael Josef},
  title     = {Label-free Electrostatic Detection of DNA Amplification by PCR Using Capacitive Field-effect Devices},
  series = {Procedia Engineering},
  volume    = {Vol. 168},
  booktitle = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2016.11.512},
  pages     = {514 -- 517},
  year      = {2016},
  abstract  = {A capacitive field-effect EIS (electrolyte-insulator-semiconductor) sensor modified with a positively charged weak polyelectrolyte of poly(allylamine hydrochloride) (PAH)/single-stranded probe DNA (ssDNA) bilayer has been used for a label-free electrostatic detection of pathogen-specific DNA amplification via polymerase chain reaction (PCR). The sensor is able to distinguish between positive and negative PCR solutions, to detect the existence of target DNA amplicons in PCR samples and thus, can be used as tool for a quick verification of DNA amplification and the successful PCR process.},
  language  = {en}
}