@inproceedings{IomdinaKiselevaKotliaretal.2020, author = {Iomdina, Elena N. and Kiseleva, Anna A. and Kotliar, Konstantin and Luzhnov, Petr V.}, title = {Quantification of Choroidal Blood Flow Using the OCT-A System Based on Voxel Scan Processing}, series = {2020 International Conference on Biomedical Innovations and Applications (BIA)}, booktitle = {2020 International Conference on Biomedical Innovations and Applications (BIA)}, isbn = {978-1-7281-7073-2}, doi = {10.1109/BIA50171.2020.9244511}, pages = {41 -- 44}, year = {2020}, language = {en} } @article{KotliarBaumannVilseretal.2011, author = {Kotliar, Konstantin and Baumann, Marcus and Vilser, Walthard and Lanzl, Ines M.}, title = {Pulse wave velocity in retinal arteries of healthy volunteers}, series = {British Journal of Ophthalmology (eBJO)}, volume = {95}, journal = {British Journal of Ophthalmology (eBJO)}, number = {11}, publisher = {BMJ Publ. Group}, address = {London}, isbn = {1468-2079}, pages = {675 -- 679}, year = {2011}, language = {en} } @article{HacklMuellerStaatetal.2016, author = {Hackl, Michael and M{\"u}ller, Lars-Peter and Staat, Manfred and Kahmann, Stephanie Lucina and Wegmann, Kilian}, title = {Proximal phalangeal neck fractures of the hand — a biomechanical comparison of three fixation techniques}, series = {Knee surgery, sports traumatology, arthroscopy}, volume = {Volume 24}, journal = {Knee surgery, sports traumatology, arthroscopy}, number = {Supplement 1}, publisher = {Springer}, address = {Berlin}, issn = {0942-2056}, doi = {10.1007/s00167-016-4080-7}, pages = {148 -- 149}, year = {2016}, abstract = {Plate osteosynthesis of displaced proximal phalangeal neck fractures of the hand allows early mobilization due to a stable internal fixation. Nevertheless, joint stiffness—because of soft tissue irritation—represents a common complication leading to high complication rates. Del Pinal et al. recently reported promising clinical results for a new, minimally invasive fixation technique with a cannulated headless intramedullary compression screw. Hence, the aim of this study was to compare plate fixation of proximal phalangeal neck fractures to less two less invasive techniques: Crossed k-wire fixation and intramedullary screw fixation. We hypothesized that these fixation techniques provide inferior stability when compared to plate osteosynthesis.}, language = {en} } @article{DigelZerlinTemizArtmannetal.2007, author = {Digel, Ilya and Zerlin, Kay and Temiz Artmann, Ayseg{\"u}l and Engels, S.}, title = {Protein dynamics in thermosensation}, series = {Regenerative medicine. 2 (2007), H. 5}, journal = {Regenerative medicine. 2 (2007), H. 5}, isbn = {1746-0751}, pages = {533 -- 533}, year = {2007}, language = {en} } @incollection{SavitskayaKistaubayevaAkimbekovetal.2020, author = {Savitskaya, Irina S. and Kistaubayeva, Aida S. and Akimbekov, Nuraly and Digel, Ilya and Shokatayeva, Dina and Zhubanova, Azhar Achmet}, title = {Prospective Use of Probiotics Immobilized on Sorbents with Nanostructured Surfaces}, series = {Carbon Nanomaterials in Biomedicine and the Environment}, booktitle = {Carbon Nanomaterials in Biomedicine and the Environment}, publisher = {Jenny Stanford Publishing}, address = {Singapore}, isbn = {978-981-4800-27-3}, doi = {10.1201/9780429428647-12}, pages = {229 -- 267}, year = {2020}, abstract = {Activated carbons are known as excellent adsorbents. Their applications include the adsorptive removal of color, odor, taste, undesirable organic and inorganic pollutants from drinking and waste water; air purification in inhabited spaces; purification of many chemicals, pharmaceutical products and many others. This chapter elucidates the role of normal microflora in the maintenance of human health and presents materials on possible clinical displays of microecological infringements and ways of their correction. It presents new developments concerning new probiotics with immobilized Lactobacillus and Bacillus. The chapter considers the mechanisms of the intestine disbacteriosis correction by sorbed probiotics. It demonstrates the advantages and creation prospects of immobilized probiotics developed on the basis of carbonized rice husk. There are great prospects for the development of medical biotechnology due to use of carbon sorbents with a nanostructured surface. Microbial communities form a biocenosis of the biotope and together with the host organism create permanent or temporary ecosystems.}, language = {en} } @article{BlomeSeboldtDachwaldetal.2004, author = {Blome, Hans-Joachim and Seboldt, Wolfgang and Dachwald, Bernd and Richter, Lutz}, title = {Proposal for an integrated European Space Exploration Study}, series = {Space Debris and Space Traffic Management Symposium 2004 : proceedings of the International Academy of Astronautics Space Debris and Space Traffic Management Symposium, held in conjunction with the 55th International Astronautical Congress (IAC), October 4 - 8, 2004, Vancouver, British Columbia, Canada / ed. by Joerg Bendisch}, journal = {Space Debris and Space Traffic Management Symposium 2004 : proceedings of the International Academy of Astronautics Space Debris and Space Traffic Management Symposium, held in conjunction with the 55th International Astronautical Congress (IAC), October 4 - 8, 2004, Vancouver, British Columbia, Canada / ed. by Joerg Bendisch}, publisher = {Univelt}, address = {San Diego, Calif.}, isbn = {0-87703-523-7}, pages = {XI, 432 S. : Ill., graph. Darst.}, year = {2004}, language = {en} } @inproceedings{SeboldtBlomeDachwaldetal.2004, author = {Seboldt, Wolfgang and Blome, Hans-Joachim and Dachwald, Bernd and Richter, Lutz}, title = {Proposal for an integrated European space exploration strategy}, series = {55th International Astronautical Congress of the International Astronautical Federation, the International Academy of Astronautics, and the International Institute of Space Law}, booktitle = {55th International Astronautical Congress of the International Astronautical Federation, the International Academy of Astronautics, and the International Institute of Space Law}, pages = {1 -- 10}, year = {2004}, abstract = {Recently, in his vision for space exploration, US president Bush announced to extend human presence across the solar system, starting with a human return to the Moon as early as 2015 in preparation for human exploration of Mars and other destinations. In Europe, an exploration program, termed AURORA, was established by ESA in 2001 - funded on a voluntary basis by ESA member states - with a clear focus on Mars and the ultimate goal of landing humans on Mars around 2030 in international cooperation. In 2003, a Human Spaceflight Vision Group was appointed by ESA with the task to develop a vision for the role of human spaceflight during the next quarter of the century. The resulting vision focused on a European-led lunar exploration initiative as part of a multi-decade, international effort to strengthen European identity and economy. After a review of the situation in Europe concerning space exploration, the paper outlines an approach for a consistent positioning of exploration within the existing European space programs, identifies destinations, and develops corresponding scenarios for an integrated strategy, starting with robotic missions to the Moon, Mars, and near-Earth asteroids. The interests of the European planetary in-situ science community, which recently met at DLR Cologne, are considered. Potential robotic lunar missions comprise polar landings to search for frozen volatiles and a sample return. For Mars, the implementation of a modest robotic landing mission in 2009 to demonstrate the capability for landing and prepare more ambitious and complex missions is discussed. For near-Earth asteroid exploration, a low-cost in-situ technology demonstration mission could yield important results. All proposed scenarios offer excellent science and could therefore create synergies between ESA's mandatory and optional programs in the area of planetary science and exploration. The paper intents to stimulate the European discussion on space exploration and reflects the personal view of the authors.}, language = {en} } @article{JiminezGermanBehbahaniMiettinenetal.2013, author = {Jiminez German, Salvador and Behbahani, Mehdi and Miettinen, Susanna and Grijpma, Dirk W. and Haimi, Suvi P.}, title = {Proliferation and differentiation of adipose stem cells towards smooth muscle cells on poly(trimethylene carbonate) membranes}, series = {Macromolecular symposia}, volume = {Vol. 334}, journal = {Macromolecular symposia}, number = {Iss. 1}, publisher = {Wiley}, address = {Weinheim}, issn = {0258-0322}, pages = {133 -- 142}, year = {2013}, language = {en} } @article{KoppSchmeetsGosauetal.2019, author = {Kopp, Alexander and Schmeets, Ralf and Gosau, Martin and Friedrich, Reinhard E. and Fuest, Sandra and Behbahani, Mehdi and Barbeck, Mike and Rutkowski, Rico and Burg, Simon and Kluwe, Lan and Henningsen, Anders}, title = {Production and Characterization of Porous Fibroin Scaffolds for Regenerative Medical Application}, series = {In Vivo}, volume = {33}, journal = {In Vivo}, number = {3}, issn = {1791-7549}, doi = {10.21873/invivo.11536}, pages = {757 -- 762}, year = {2019}, language = {en} } @inproceedings{Staat2006, author = {Staat, Manfred}, title = {Problems and chances for probabilistic fracture mechanics in the analysis of steel pressure boundary reliability. - {\"U}berarb. Ausg.}, year = {2006}, abstract = {In: Technical feasibility and reliability of passive safety systems for nuclear power plants. Proceedings of an Advisory Group Meeting held in J{\"u}lich, 21-24 November 1994. - Vienna , 1996. - Seite: 43 - 55 IAEA-TECDOC-920 Abstract: It is shown that the difficulty for probabilistic fracture mechanics (PFM) is the general problem of the high reliability of a small population. There is no way around the problem as yet. Therefore what PFM can contribute to the reliability of steel pressure boundaries is demon­strated with the example of a typical reactor pressure vessel and critically discussed. Although no method is distinguishable that could give exact failure probabilities, PFM has several addi­tional chances. Upper limits for failure probability may be obtained together with trends for design and operating conditions. Further, PFM can identify the most sensitive parameters, improved control of which would increase reliability. Thus PFM should play a vital role in the analysis of steel pressure boundaries despite all shortcomings.}, subject = {Bruchmechanik}, language = {en} } @article{StaatHeitzer2003, author = {Staat, Manfred and Heitzer, M.}, title = {Probabilistic limit and shakedown problems}, series = {Numerical Methods for Limit and Shakedown Analysis. Deterministic and Probabilistic Approach. NIC Series Vol. 15 / Ed. by Staat, M; Heitzer, M.}, journal = {Numerical Methods for Limit and Shakedown Analysis. Deterministic and Probabilistic Approach. NIC Series Vol. 15 / Ed. by Staat, M; Heitzer, M.}, publisher = {John von Neumann Institute for Computing (NIC)}, address = {J{\"u}lich}, isbn = {3-00-010001-6}, pages = {217 -- 268}, year = {2003}, language = {en} } @incollection{StaatHeitzer2003, author = {Staat, Manfred and Heitzer, Michael}, title = {Probabilistic limit and shakedown problems}, series = {Numerical methods for limit and shakedown analysis. Deterministic and probabilistic problems}, volume = {15}, booktitle = {Numerical methods for limit and shakedown analysis. Deterministic and probabilistic problems}, editor = {Staat, Manfred and Heitzer, Michael}, publisher = {John von Neumann Institute for Computing (NIC)}, address = {J{\"u}lich}, isbn = {3-00-010001-6}, pages = {217 -- 268}, year = {2003}, language = {en} } @article{TranKreissigStaat2009, author = {Tran, Thanh Ngoc and Kreißig, R. and Staat, Manfred}, title = {Probabilistic limit and shakedown analysis of thin plates and shells}, series = {Structural safety. 31 (2009), H. 1}, journal = {Structural safety. 31 (2009), H. 1}, publisher = {-}, isbn = {0167-4730}, pages = {1 -- 18}, year = {2009}, language = {en} } @article{Digel2011, author = {Digel, Ilya}, title = {Primary thermosensory events in cells}, series = {Transient receptor potential channels / Md. Shahidul Islam, ed.}, journal = {Transient receptor potential channels / Md. Shahidul Islam, ed.}, publisher = {Springer}, address = {Dordrecht [u.a.]}, isbn = {978-94-007-0264-6}, pages = {451 -- 468}, year = {2011}, language = {en} } @inproceedings{AbelPerezVianaCiritsisetal.2017, author = {Abel, Alexander and P{\´e}rez-Viana, Daniel and Ciritsis, Bernard and Staat, Manfred}, title = {Prevention of femur neck fractures through femoroplasty}, series = {2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West}, booktitle = {2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West}, editor = {Erni, Daniel and Fischerauer, Alice and Himmel, J{\"o}rg and Seeger, Thomas and Thelen, Klaus}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-9814801-9-1}, doi = {10.17185/duepublico/43984}, pages = {114 -- 115}, year = {2017}, language = {en} } @article{RauschKahmannBaltschunetal.2020, author = {Rausch, Valentin and Kahmann, Stephanie Lucina and Baltschun, Christoph and Staat, Manfred and M{\"u}ller, Lars P. and Wegmann, Kilian}, title = {Pressure distribution to the distal biceps tendon at the radial tuberosity: a biomechanical study}, series = {The Journal of Hand Surgery}, volume = {45}, journal = {The Journal of Hand Surgery}, number = {8}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0363-5023}, doi = {10.1016/j.jhsa.2020.01.006}, pages = {776.e1 -- 776.e9}, year = {2020}, abstract = {Purpose Mechanical impingement at the narrow radioulnar space of the tuberosity is believed to be an etiological factor in the injury of the distal biceps tendon. The aim of the study was to compare the pressure distribution at the proximal radioulnar space between 2 fixation techniques and the intact state. Methods Six right arms and 6 left arms from 5 female and 6 male frozen specimens were used for this study. A pressure transducer was introduced at the height of the radial tuberosity with the intact distal biceps tendon and after 2 fixation methods: the suture-anchor and the cortical button technique. The force (N), maximum pressure (kPa) applied to the radial tuberosity, and the contact area (mm²) of the radial tuberosity with the ulna were measured and differences from the intact tendon were detected from 60° supination to 60° pronation in 15° increments with the elbow in full extension and in 45° and 90° flexion of the elbow. Results With the distal biceps tendon intact, the pressures during pronation were similar regardless of extension and flexion and were the highest at 60° pronation with 90° elbow flexion (23.3 ± 53.5 kPa). After repair of the tendon, the mean peak pressure, contact area, and total force showed an increase regardless of the fixation technique. Highest peak pressures were found using the cortical button technique at 45° flexion of the elbow and 60° pronation. These differences were significantly different from the intact tendon. The contact area was significantly larger in full extension and 15°, 30°, and 60° pronation using the cortical button technique. Conclusions Pressures on the distal biceps tendon at the radial tuberosity increase during pronation, especially after repair of the tendon. Clinical relevance Mechanical impingement could play a role in both the etiology of primary distal biceps tendon ruptures and the complications occurring after fixation of the tendon using certain techniques.}, language = {en} } @inproceedings{PeloniCeriottiDachwald2015, author = {Peloni, A. and Ceriotti, M. and Dachwald, Bernd}, title = {Preliminary trajectory design of a multiple NEO rendezvous mission through solar sailing}, series = {Proceedings of the International Astronautical Congress, IAC, Vol. 8, 2014}, booktitle = {Proceedings of the International Astronautical Congress, IAC, Vol. 8, 2014}, publisher = {Curran}, address = {Red Hook, NY}, isbn = {978-1-63439-986-9}, pages = {5352 -- 5366}, year = {2015}, language = {en} } @incollection{KnottSofroniaGerressenetal.2014, author = {Knott, Thomas C. and Sofronia, Raluca E. and Gerressen, Marcus and Law, Yuen and Davidescu, Arjana and Savii, George G. and Gatzweiler, Karl-Heinz and Staat, Manfred and Kuhlen, Torsten W.}, title = {Preliminary bone sawing model for a virtual reality-based training simulator of bilateral sagittal split osteotomy}, series = {Biomedical simulation : 6th International Symposium, ISBMS 2014, Strasbourg, France, October 16-17, 2014 : proceedings (Lecture notes in computer science : vol. 8789)}, booktitle = {Biomedical simulation : 6th International Symposium, ISBMS 2014, Strasbourg, France, October 16-17, 2014 : proceedings (Lecture notes in computer science : vol. 8789)}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-12057-7 (Online)}, doi = {10.1007/978-3-319-12057-7_1}, pages = {1 -- 10}, year = {2014}, abstract = {Successful bone sawing requires a high level of skill and experience, which could be gained by the use of Virtual Reality-based simulators. A key aspect of these medical simulators is realistic force feedback. The aim of this paper is to model the bone sawing process in order to develop a valid training simulator for the bilateral sagittal split osteotomy, the most often applied corrective surgery in case of a malposition of the mandible. Bone samples from a human cadaveric mandible were tested using a designed experimental system. Image processing and statistical analysis were used for the selection of four models for the bone sawing process. The results revealed a polynomial dependency between the material removal rate and the applied force. Differences between the three segments of the osteotomy line and between the cortical and cancellous bone were highlighted.}, language = {en} } @article{KezerashviliDachwald2021, author = {Kezerashvili, Roman Ya and Dachwald, Bernd}, title = {Preface: Solar sailing: Concepts, technology, and missions II}, series = {Advances in Space Research}, volume = {67}, journal = {Advances in Space Research}, number = {9}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0273-1177}, doi = {10.1016/j.asr.2021.01.037}, pages = {2559 -- 2560}, year = {2021}, language = {en} } @article{SavitskayaZhantlessovaKistaubayevaetal.2023, author = {Savitskaya, Irina and Zhantlessova, Sirina and Kistaubayeva, Aida and Ignatova, Ludmila and Shokatayeva, Dina and Sinyavsky, Yuriy and Kushugulova, Almagul and Digel, Ilya}, title = {Prebiotic cellulose-pullulan matrix as a "vehicle" for probiotic biofilm delivery to the host large intestine}, series = {Polymers}, journal = {Polymers}, number = {16(1)}, publisher = {MDPI}, address = {Basel}, doi = {10.3390/polym16010030}, pages = {Artikel 30}, year = {2023}, abstract = {This study describes the development of a new combined polysaccharide-matrix-based technology for the immobilization of Lactobacillus rhamnosus GG (LGG) bacteria in biofilm form. The new composition allows for delivering the bacteria to the digestive tract in a manner that improves their robustness compared with planktonic cells and released biofilm cells. Granules consisting of a polysaccharide matrix with probiotic biofilms (PMPB) with high cell density (>9 log CFU/g) were obtained by immobilization in the optimized nutrient medium. Successful probiotic loading was confirmed by fluorescence microscopy and scanning electron microscopy. The developed prebiotic polysaccharide matrix significantly enhanced LGG viability under acidic (pH 2.0) and bile salt (0.3\%) stress conditions. Enzymatic extract of feces, mimicking colon fluid in terms of cellulase activity, was used to evaluate the intestinal release of probiotics. PMPB granules showed the ability to gradually release a large number of viable LGG cells in the model colon fluid. In vivo, the oral administration of PMPB granules in rats resulted in the successful release of probiotics in the colon environment. The biofilm-forming incubation method of immobilization on a complex polysaccharide matrix tested in this study has shown high efficacy and promising potential for the development of innovative biotechnologies.}, language = {en} } @article{DachwaldSeboldtMacdonaldetal.2005, author = {Dachwald, Bernd and Seboldt, Wolfgang and Macdonald, Malcolm and Mengali, Giovanni and Quatra, Alessandro A. and McInnes, Colin R. and Rios-Reyes, Leonel and Scheerers, Daniel J. and Wie, Bong and G{\"o}rlich, Marianne and Lura, Franz and Diedrich, Benjamin and Baturkin, Volodymyr and Coverstone, Victoria L. and Leipold, Manfred and Garbe, Gregory P.}, title = {Potential Solar Sail Degradation Effects on Trajectory and Attitude Control}, series = {AIAA Guidance, Navigation and Control Conference and Exhibit - AIAA Modeling and Simulation Technologies Conference and Exhibit - AIAA Atmospheric Flight Mechanics Conference and Exhibit : [San Francisco, California, 15 - 18 August 2005 ; papers]. - (AIAA meeting papers on disc ; [10.]2005,16-17)}, journal = {AIAA Guidance, Navigation and Control Conference and Exhibit - AIAA Modeling and Simulation Technologies Conference and Exhibit - AIAA Atmospheric Flight Mechanics Conference and Exhibit : [San Francisco, California, 15 - 18 August 2005 ; papers]. - (AIAA meeting papers on disc ; [10.]2005,16-17)}, publisher = {American Institute of Aeronautics and Astronautics}, address = {Reston, Va.}, isbn = {1-56347-765-3}, pages = {2 CD-ROMs}, year = {2005}, language = {en} } @inproceedings{DachwaldBaturkinCoverstoneetal.2005, author = {Dachwald, Bernd and Baturkin, Volodymyr and Coverstone, Victoria and Diedrich, Ben and Garbe, Gregory and G{\"o}rlich, Marianne and Leipold, Manfred and Lura, Franz and Macdonald, Malcolm and McInnes, Colin and Mengali, Giovanni and Quarta, Alessandro and Rios-Reyes, Leonel and Scheeres, Daniel J. and Seboldt, Wolfgang and Wie, Bong}, title = {Potential effects of optical solar sail degredation on trajectory design}, series = {AAS/AIAA Astrodynamics Specialist}, booktitle = {AAS/AIAA Astrodynamics Specialist}, pages = {1 -- 23}, year = {2005}, abstract = {The optical properties of the thin metalized polymer films that are projected for solar sails are assumed to be affected by the erosive effects of the space environment. Their degradation behavior in the real space environment, however, is to a considerable degree indefinite, because initial ground test results are controversial and relevant inspace tests have not been made so far. The standard optical solar sail models that are currently used for trajectory design do not take optical degradation into account, hence its potential effects on trajectory design have not been investigated so far. Nevertheless, optical degradation is important for high-fidelity solar sail mission design, because it decreases both the magnitude of the solar radiation pressure force acting on the sail and also the sail control authority. Therefore, we propose a simple parametric optical solar sail degradation model that describes the variation of the sail film's optical coefficients with time, depending on the sail film's environmental history, i.e., the radiation dose. The primary intention of our model is not to describe the exact behavior of specific film-coating combinations in the real space environment, but to provide a more general parametric framework for describing the general optical degradation behavior of solar sails. Using our model, the effects of different optical degradation behaviors on trajectory design are investigated for various exemplary missions.}, language = {en} } @article{DachwaldBaturkinCoverstoneetal.2006, author = {Dachwald, Bernd and Baturkin, Volodymyr and Coverstone, Victoria L. and Dietrich, Benjamin and Garbe, Gregory P. and G{\"o}rlich, Marianne and Leipold, Manfred and Lura, Franz and Macdonald, Malcolm and McInnes, Colin R. and Mengali, Giovanni and Quatra, Alessandro A. and Rios-Reyes, Leonel and Scheeres, Daniel J. and Seboldt, Wolfgang and Wie, Bong}, title = {Potential Effects of Optical Solar Sail Degradation on Interplanetary Trajectory Design}, series = {Astrodynamics 2005 : proceedings of the AAS/AIAA astrodynamics conference held August 7 - 11, 2005, South Lake Tahoe, California / ed. by Bobby G. Williams. - Pt. 3. - (Advances in the astronautical sciences ; 123,3)}, journal = {Astrodynamics 2005 : proceedings of the AAS/AIAA astrodynamics conference held August 7 - 11, 2005, South Lake Tahoe, California / ed. by Bobby G. Williams. - Pt. 3. - (Advances in the astronautical sciences ; 123,3)}, publisher = {Univelt}, address = {San Diego, Calif.}, isbn = {0-87703-527-X}, pages = {2569 -- 2592}, year = {2006}, language = {en} } @article{JayaramanMummidisettyLoeschetal.2019, author = {Jayaraman, Chandrasekaran and Mummidisetty, Chaitanya Krishna and Loesch, Alexandra and Kaur, Sandi and Hoppe-Ludwig, Shenan and Staat, Manfred and Jayaraman, Arun}, title = {Postural and metabolic benefits of using a forearm support walker in older adults with impairments}, series = {Archives of Physical Medicine and Rehabilitation}, volume = {Volume 100}, journal = {Archives of Physical Medicine and Rehabilitation}, number = {Issue 4}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0003-9993}, doi = {10.1016/j.apmr.2018.10.001}, pages = {638 -- 647}, year = {2019}, language = {en} } @article{KotliarKozlovaLanzl2009, author = {Kotliar, Konstantin and Kozlova, Tatiana V. and Lanzl, Ines M.}, title = {Postoperative aqueous outflow in the human eye after glaucoma filtration surgery: biofluidmechanical considerations}, series = {Biomedizinische Technik = Biomedical Engineering}, volume = {54}, journal = {Biomedizinische Technik = Biomedical Engineering}, number = {1}, publisher = {-}, isbn = {1862-278X}, pages = {14 -- 22}, year = {2009}, language = {en} } @article{CiritsisHorbachStaatetal.2018, author = {Ciritsis, Alexander and Horbach, Andreas and Staat, Manfred and Kuhl, Christiane K. and Kraemer, Nils Andreas}, title = {Porosity and tissue integration of elastic mesh implants evaluated in vitro and in vivo}, series = {Journal of Biomedical Materials Research: Part B: Applied Biomaterials}, volume = {106}, journal = {Journal of Biomedical Materials Research: Part B: Applied Biomaterials}, number = {2}, publisher = {Wiley}, address = {New York, NY}, issn = {1552-4981}, doi = {10.1002/jbm.b.33877}, pages = {827 -- 833}, year = {2018}, abstract = {Purpose In vivo, a loss of mesh porosity triggers scar tissue formation and restricts functionality. The purpose of this study was to evaluate the properties and configuration changes as mesh deformation and mesh shrinkage of a soft mesh implant compared with a conventional stiff mesh implant in vitro and in a porcine model. Material and Methods Tensile tests and digital image correlation were used to determine the textile porosity for both mesh types in vitro. A group of three pigs each were treated with magnetic resonance imaging (MRI) visible conventional stiff polyvinylidene fluoride meshes (PVDF) or with soft thermoplastic polyurethane meshes (TPU) (FEG Textiltechnik mbH, Aachen, Germany), respectively. MRI was performed with a pneumoperitoneum at a pressure of 0 and 15 mmHg, which resulted in bulging of the abdomen. The mesh-induced signal voids were semiautomatically segmented and the mesh areas were determined. With the deformations assessed in both mesh types at both pressure conditions, the porosity change of the meshes after 8 weeks of ingrowth was calculated as an indicator of preserved elastic properties. The explanted specimens were examined histologically for the maturity of the scar (collagen I/III ratio). Results In TPU, the in vitro porosity increased constantly, in PVDF, a loss of porosity was observed under mild stresses. In vivo, the mean mesh areas of TPU were 206.8 cm2 (± 5.7 cm2) at 0 mmHg pneumoperitoneum and 274.6 cm2 (± 5.2 cm2) at 15 mmHg; for PVDF the mean areas were 205.5 cm2 (± 8.8 cm2) and 221.5 cm2 (± 11.8 cm2), respectively. The pneumoperitoneum-induced pressure increase resulted in a calculated porosity increase of 8.4\% for TPU and of 1.2\% for PVDF. The mean collagen I/III ratio was 8.7 (± 0.5) for TPU and 4.7 (± 0.7) for PVDF. Conclusion The elastic properties of TPU mesh implants result in improved tissue integration compared to conventional PVDF meshes, and they adapt more efficiently to the abdominal wall. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 827-833, 2018.}, language = {en} } @article{MaggakisKelemenDigelArtmann2005, author = {Maggakis-Kelemen, Christina and Digel, Ilya and Artmann, Gerhard}, title = {Polystyrene sulfonate/Polyallylamine hydrochloride microcapsules as potential artificial red blood cells - improvement of capsule flexibility}, series = {Biomedizinische Technik. 50 (2005), H. Erg.-Bd. 1}, journal = {Biomedizinische Technik. 50 (2005), H. Erg.-Bd. 1}, pages = {324 -- 326}, year = {2005}, language = {en} } @techreport{StoelzleFeixThomasEngelstaedteretal.2021, author = {St{\"o}lzle-Feix, Sonja and Thomas, Ulrich and Engelst{\"a}dter, Max and Goßmann, Matthias and Linder, Peter and Staat, Manfred and Raman, Aravind Hariharan and Jung, Alexander and Fertig, Niels}, title = {Plattformtechnologie f{\"u}r kardiale Sicherheitspharmakologie basierend auf teilsynthetischem Herzmuskelgewebe (FLEXcyte) : gemeinsamer FuE-Abschlussbericht aller Partner des Verbundprojektes : Projektlaufzeit: 01.10.2018 bis 30.09.2020}, publisher = {Nanion Technologies GmbH}, address = {M{\"u}nchen}, doi = {10.2314/KXP:1813208581}, pages = {IV, 85 Seiten, 2 ungez{\"a}hlte Seiten}, year = {2021}, language = {de} } @article{MichaelMayerWeberetal.2017, author = {Michael, Hackl and Mayer, Katharina and Weber, Mareike and Staat, Manfred and van Riet, Roger and Burkhart, Klau Josef and M{\"u}ller, Lars Peter and Wegmann, Kilian}, title = {Plate osteosynthesis of proximal ulna fractures : a biomechanical micromotion analysis}, series = {The journal of hand surgery}, volume = {42}, journal = {The journal of hand surgery}, number = {10}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0363-5023}, doi = {10.1016/j.jhsa.2017.05.014}, pages = {834.e1 -- 834.e7}, year = {2017}, language = {en} } @article{ArampatzisKaramanidisMademlietal.2009, author = {Arampatzis, Adamantios and Karamanidis, Kiros and Mademli, Lida and Albracht, Kirsten}, title = {Plasticity of the human tendon to short and long-term mechanical loading}, series = {Exercise and Sport Sciences Reviews}, volume = {37}, journal = {Exercise and Sport Sciences Reviews}, number = {2}, issn = {1538-3008}, doi = {10.1097/JES.0b013e31819c2e1d}, pages = {66 -- 72}, year = {2009}, language = {en} } @article{ArampatzisPeperBierbaumetal.2010, author = {Arampatzis, Adamantios and Peper, Andreas and Bierbaum, Stefanie and Albracht, Kirsten}, title = {Plasticity of human Achilles tendon mechanical and morphological properties in response to cyclic strain}, series = {Journal of Biomechanics}, volume = {43}, journal = {Journal of Biomechanics}, number = {16}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0021-9290}, doi = {10.1016/j.jbiomech.2010.08.014}, pages = {3073 -- 3079}, year = {2010}, abstract = {The purpose of the current study in combination with our previous published data (Arampatzis et al., 2007) was to examine the effects of a controlled modulation of strain magnitude and strain frequency applied to the Achilles tendon on the plasticity of tendon mechanical and morphological properties. Eleven male adults (23.9±2.2 yr) participated in the study. The participants exercised one leg at low magnitude tendon strain (2.97±0.47\%), and the other leg at high tendon strain magnitude (4.72±1.08\%) of similar frequency (0.5 Hz, 1 s loading, 1 s relaxation) and exercise volume (integral of the plantar flexion moment over time) for 14 weeks, 4 days per week, 5 sets per session. The exercise volume was similar to the intervention of our earlier study (0.17 Hz frequency; 3 s loading, 3 s relaxation) allowing a direct comparison of the results. Before and after the intervention ankle joint moment has been measured by a dynamometer, tendon-aponeurosis elongation by ultrasound and cross-sectional area of the Achilles tendon by magnet resonance images (MRI). We found a decrease in strain at a given tendon force, an increase in tendon-aponeurosis stiffness and tendon elastic modulus of the Achilles tendon only in the leg exercised at high strain magnitude. The cross-sectional area (CSA) of the Achilles tendon did not show any statistically significant (P>0.05) differences to the pre-exercise values in both legs. The results indicate a superior improvement in tendon properties (stiffness, elastic modulus and CSA) at the low frequency (0.17 Hz) compared to the high strain frequency (0.5 Hz) protocol. These findings provide evidence that the strain magnitude applied to the Achilles tendon should exceed the value, which occurs during habitual activities to trigger adaptational effects and that higher tendon strain duration per contraction leads to superior tendon adaptational responses.}, language = {en} } @article{Staat2004, author = {Staat, Manfred}, title = {Plastic collapse analysis of longitudinally flawed pipes and vessels}, series = {Nuclear Engineering and Design. 234 (2004), H. 1-3}, journal = {Nuclear Engineering and Design. 234 (2004), H. 1-3}, isbn = {0029-5493}, pages = {25 -- 43}, year = {2004}, language = {en} } @article{Staat2004, author = {Staat, Manfred}, title = {Plastic collapse analysis of longitudinally flawed pipes and vessels}, year = {2004}, abstract = {Improved collapse loads of thick-walled, crack containing pipes and vessels are suggested. Very deep cracks have a residual strength which is better modelled by a global limit load. In all burst tests, the ductility of pressure vessel steels was sufficiently high whereby the burst pressure could be predicted by limit analysis with no need to apply fracture mechanics. The relative prognosis error increases however, for long and deep defects due to uncertainties of geometry and strength data.}, subject = {Druckbeh{\"a}lter}, language = {en} } @inproceedings{DigelTemizArtmannNojimaetal.2003, author = {Digel, Ilya and Temiz Artmann, Ayseg{\"u}l and Nojima, H. and Artmann, Gerhard}, title = {Plasma-generated cluster ions' effects on indoor microflora : [abstract]}, year = {2003}, abstract = {Recently, SHARP corporation has developed the world's first "Plasma Cluster Ions® (PCI)" air purification technology, which uses plasma discharge to generate cluster ions. The new Plasma Cluster Device releases positive and negative ions into the air, which are harmless to humans and are able to decompose and deactivate airborne substances by chemical reactions. In the past, phenomenological tests on the efficacy of the PCI air purification technology on microbial cells have been conducted. In most cases, it has been shown that PCI demonstrated strongly pronounced killing effects on microorganisms. However, the particular mechanisms of PCI action still have to be uncovered.}, subject = {Clusterion}, language = {en} } @inproceedings{DigelTemizArtmannArtmannetal.2003, author = {Digel, Ilya and Temiz Artmann, Ayseg{\"u}l and Artmann, Gerhard and Nojima, H.}, title = {Plasma cluster ions (PCI) influence on microbial cells viability : [abstract]}, year = {2003}, abstract = {Recently, SHARP corporation has developed the world's first "Plasma Cluster Ions (PCI)" air purification technology, which uses plasma discharge to generate cluster ions. The new plasma cluster device releases into the air positive and negative ions, which are harmless to humans and are able to decompose and deactivate airborne substances by chemical reactions. A lot of phenomenological tests of the PCI air purification technology on microbial cells have been conducted. And, in most cases, it has been shown that PCI demonstrate strongly pronounced killing effect. Although, the particular mechanisms of PCI action are still not evident. We studied variations in resistance to PCI among gram-positive airborne microorganisms, as well as some dose-dependent, spatial, cultural and biochemical properties of PCI action in respect of Staphylococcus spp, Enterococcus spp, Micrococcus spp.}, subject = {Clusterion}, language = {en} } @techreport{Artmann2011, author = {Artmann, Gerhard}, title = {Plant mutant scanner : Hochdurchsatzscanner zur Charakterisierung von Pflanzenmutanten. Abschlussbericht ; FHprofUnd ; PhytoScan ; Laufzeit des Vorhabens: 01.07.2008 - 30.06.2011}, publisher = {Technische Informationsbibliothek u. Universit{\"a}tsbibliothek}, address = {Aachen}, doi = {10.2314/GBV:747569150}, year = {2011}, language = {de} } @article{StadlerGarveyEmbsetal.2014, author = {Stadler, Alexander Maximilian and Garvey, Christopher J. and Embs, Jan Peter and Koza, Michael Marek and Unruh, Tobias and Artmann, Gerhard and Zaccai, Guiseppe}, title = {Picosecond dynamics in haemoglobin from different species: A quasielastic neutron scattering study}, series = {Biochimica et biophysica acta (BBA): General Subjects}, volume = {1840}, journal = {Biochimica et biophysica acta (BBA): General Subjects}, number = {10}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1872-8006 (E-Journal); 0304-4165 (Print)}, doi = {10.1016/j.bbagen.2014.06.007}, pages = {2989 -- 2999}, year = {2014}, language = {en} } @article{KotliarKoshitzSvetlowaetal.2006, author = {Kotliar, Konstantin and Koshitz, I. N. and Svetlowa, O. V. and Zaseeva, M. V.}, title = {Physiological principles of hypotensive therapy of open-angle glaucoma during presbyopic period. Part II Promising algorithms of practical sparing applications / Koshitz, I. N. ; Svetlova, O. V. ; Zaseeva, M. V. ; Shuhaev, S. V. ; Makarov, F. N. ; Kotliar}, series = {Glaukoma (2006)}, journal = {Glaukoma (2006)}, publisher = {-}, pages = {51 -- 70}, year = {2006}, language = {en} } @article{KotliarKoshitzSvetlovaetal.2006, author = {Kotliar, Konstantin and Koshitz, I. N. and Svetlova, O. V. and Zaseeva, M. V.}, title = {Physiological principles of hypotensive therapy of open-angle glaucoma during presbyopic period. Part I Initial theoretical presuppositions, hypotheses and facts / Koshitz, I. N. ; Svetlova, O. V. ; Zaseeva, M. V. ; Shuhaev, S. V. ; Makarov, F. N. ; Kotli}, series = {Glaukoma (2006)}, journal = {Glaukoma (2006)}, publisher = {-}, pages = {35 -- 53}, year = {2006}, language = {en} } @phdthesis{BassamAbduljabbar2015, author = {Bassam Abduljabbar, Rasha}, title = {Physikalisch-chemische Steuerung der Proteinstabilit{\"a}t in biologischen Systemen}, year = {2015}, language = {de} } @article{SavitskayaKistaubayevaDigeletal.2017, author = {Savitskaya, I. S. and Kistaubayeva, A. S. and Digel, Ilya and Shokatayeva, D. H.}, title = {Physicochemical and Antibacterial Properties of Composite Films Based on Bacterial Cellulose and Chitosan for Wound Dressing Materials}, series = {Eurasian Chemico-Technological Journal}, volume = {19}, journal = {Eurasian Chemico-Technological Journal}, number = {3}, issn = {2522-4867}, doi = {10.18321/ectj670}, pages = {255 -- 264}, year = {2017}, language = {en} } @article{DuongNguyenStaat2015, author = {Duong, Minh Tuan and Nguyen, Nhu Huynh and Staat, Manfred}, title = {Physical response of hyperelastic models for composite materials and soft tissues}, series = {Asia pacific journal on computational engineering}, volume = {2}, journal = {Asia pacific journal on computational engineering}, number = {3 (December 2015)}, issn = {2196-1166}, doi = {10.1186/s40540-015-0015-x}, pages = {1 -- 18}, year = {2015}, language = {en} } @incollection{DuongNguyenStaat2017, author = {Duong, Minh Tuan and Nguyen, Nhu Huynh and Staat, Manfred}, title = {Physical response of hyperelastic models for composite materials and soft tissues}, series = {Advances in Composite Material}, booktitle = {Advances in Composite Material}, publisher = {Scientific Research Publishing}, address = {Wuhan}, isbn = {978-1-61896-300-0 (Hardcover), 978-1-61896-299-7 (Paperback)}, pages = {316}, year = {2017}, language = {en} } @article{ArtmannZerlinDigeletal.2007, author = {Artmann, Gerhard and Zerlin, Kay and Digel, Ilya and Stadler, Andreas M.}, title = {Physical discontinuities at body temperature in human red blood cells / Artmann, GM ; Zerlin, K ; Digel, I ; Stadler, A ; Zaccai, G ; Temiz, AA}, series = {Tissue Engineering. 13 (2007), H. 7}, journal = {Tissue Engineering. 13 (2007), H. 7}, isbn = {1076-3279}, pages = {1778 -- 1778}, year = {2007}, language = {en} } @article{HeiligersSchoutetensDachwald2021, author = {Heiligers, Jeannette and Schoutetens, Frederic and Dachwald, Bernd}, title = {Photon-sail equilibria in the alpha centauri system}, series = {Journal of Guidance, Control, and Dynamics}, volume = {44}, journal = {Journal of Guidance, Control, and Dynamics}, number = {5}, issn = {1533-3884}, doi = {10.2514/1.G005446}, pages = {1053 -- 1061}, year = {2021}, language = {en} } @article{ArinkinDigelPorstetal.2014, author = {Arinkin, Vladimir and Digel, Ilya and Porst, Dariusz and Temiz Artmann, Ayseg{\"u}l and Artmann, Gerhard}, title = {Phenotyping date palm varieties via leaflet cross-sectional imaging and artificial neural network application}, series = {BMC bioinformatics}, volume = {15}, journal = {BMC bioinformatics}, number = {55}, issn = {1471-2105}, doi = {10.1186/1471-2105-15-55}, pages = {1 -- 8}, year = {2014}, abstract = {Background True date palms (Phoenix dactylifera L.) are impressive trees and have served as an indispensable source of food for mankind in tropical and subtropical countries for centuries. The aim of this study is to differentiate date palm tree varieties by analysing leaflet cross sections with technical/optical methods and artificial neural networks (ANN). Results Fluorescence microscopy images of leaflet cross sections have been taken from a set of five date palm tree cultivars (Hewlat al Jouf, Khlas, Nabot Soltan, Shishi, Um Raheem). After features extraction from images, the obtained data have been fed in a multilayer perceptron ANN with backpropagation learning algorithm. Conclusions Overall, an accurate result in prediction and differentiation of date palm tree cultivars was achieved with average prediction in tenfold cross-validation is 89.1\% and reached 100\% in one of the best ANN.}, language = {en} } @techreport{ArtmannBaeumler2002, author = {Artmann, Gerhard and B{\"a}umler, H.}, title = {Pharmamikrocontainer mit designgesteuerter Permeabilit{\"a}t als Transporter f{\"u}r ausgew{\"a}hlte Pharmaka. Ein Gemeinschaftsprojekt im Forschungsschwerpunkt "Celluar Engineering" [Laufzeit: 01.09.2000 - 28.02.2002]}, publisher = {FH Aachen}, address = {J{\"u}lich}, year = {2002}, language = {de} } @inproceedings{SchartnerLoebDachwaldetal.2009, author = {Schartner, Karl-Heinz and Loeb, H. W. and Dachwald, Bernd and Ohndorf, Andreas}, title = {Perspectives of electric propulsion for outer planetary and deep space missions}, series = {European Planetary Science Congress 2009}, booktitle = {European Planetary Science Congress 2009}, pages = {416 -- 416}, year = {2009}, abstract = {Solar-electric propulsion (SEP) is superior with respect to payload capacity, flight time and flexible launch window to the conventional interplanetary transfer method using chemical propulsion combined with gravity assists. This fact results from the large exhaust velocities of electric low-thrust propulsion and is favourable also for missions to the giant planets, Kuiper-belt objects and even for a heliopause probe (IHP) as shown in three studies by the authors funded by DLR. They dealt with a lander for Europa and a sample return mission from a mainbelt asteroid [1], with the TANDEM mission [2]; the third recent one investigates electric propulsion for the transfer to the edge of the solar system. All studies are based on triple-junction solar arrays, on rf-ion thrusters of the qualified RIT-22 type and they use the intelligent trajectory optimization program InTrance [3].}, language = {en} } @article{KuchlerGuenthnerRibeiroetal.2023, author = {Kuchler, Timon and G{\"u}nthner, Roman and Ribeiro, Andrea and Hausinger, Renate and Streese, Lukas and W{\"o}hnl, Anna and Kesseler, Veronika and Negele, Johanna and Assali, Tarek and Carbajo-Lozoya, Javier and Lech, Maciej and Adorjan, Kristina and Stubbe, Hans Christian and Hanssen, Henner and Kotliar, Konstantin and Haller, Berhard and Heemann, Uwe and Schmaderer, Christoph}, title = {Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation}, volume = {26}, publisher = {Springer Nature}, address = {Dordrecht}, doi = {10.1007/s10456-023-09885-6}, pages = {547 -- 563}, year = {2023}, abstract = {Background Post-COVID-19 syndrome (PCS) is a lingering disease with ongoing symptoms such as fatigue and cognitive impairment resulting in a high impact on the daily life of patients. Understanding the pathophysiology of PCS is a public health priority, as it still poses a diagnostic and treatment challenge for physicians. Methods In this prospective observational cohort study, we analyzed the retinal microcirculation using Retinal Vessel Analysis (RVA) in a cohort of patients with PCS and compared it to an age- and gender-matched healthy cohort (n = 41, matched out of n = 204). Measurements and main results PCS patients exhibit persistent endothelial dysfunction (ED), as indicated by significantly lower venular flicker-induced dilation (vFID; 3.42\% ± 1.77\% vs. 4.64\% ± 2.59\%; p = 0.02), narrower central retinal artery equivalent (CRAE; 178.1 [167.5-190.2] vs. 189.1 [179.4-197.2], p = 0.01) and lower arteriolar-venular ratio (AVR; (0.84 [0.8-0.9] vs. 0.88 [0.8-0.9], p = 0.007). When combining AVR and vFID, predicted scores reached good ability to discriminate groups (area under the curve: 0.75). Higher PCS severity scores correlated with lower AVR (R = - 0.37 p = 0.017). The association of microvascular changes with PCS severity were amplified in PCS patients exhibiting higher levels of inflammatory parameters. Conclusion Our results demonstrate that prolonged endothelial dysfunction is a hallmark of PCS, and impairments of the microcirculation seem to explain ongoing symptoms in patients. As potential therapies for PCS emerge, RVA parameters may become relevant as clinical biomarkers for diagnosis and therapy management.}, language = {en} } @article{AminTemizArtmannArtmannetal.2009, author = {Amin, Rashid and Temiz Artmann, Ayseg{\"u}l and Artmann, Gerhard and Lazarovici, Philip and Lelkes, Peter I.}, title = {Permeability of an In Vitro Model of Blood Brain Barrier (BBB)}, series = {13th International Conference on Biomedical Engineering / Lim, Chwee Teck [Ed.]}, journal = {13th International Conference on Biomedical Engineering / Lim, Chwee Teck [Ed.]}, isbn = {978-3-540-92841-6}, pages = {81 -- 84}, year = {2009}, language = {en} } @inproceedings{DachwaldSeboldtHaeusler2002, author = {Dachwald, Bernd and Seboldt, Wolfgang and H{\"a}usler, Bernd}, title = {Performance requirements for near-term interplanetary solar sailcraft missions}, series = {6th International AAAF Symposium on Space Propulsion: Propulsion for Space Transportation of the XXIst Century}, booktitle = {6th International AAAF Symposium on Space Propulsion: Propulsion for Space Transportation of the XXIst Century}, pages = {9 Seiten}, year = {2002}, abstract = {Solar sailcraft provide a wide range of opportunities for high-energy low-cost missions. To date, most mission studies require a rather demanding performance that will not be realized by solar sailcraft of the first generation. However, even with solar sailcraft of moderate performance, scientifically relevant missions are feasible. This is demonstrated with a Near Earth Asteroid sample return mission and various planetary rendezvous missions.}, language = {en} } @inproceedings{SavitskayaKistaubayevaAkimbekovetal.2013, author = {Savitskaya, Irina S. and Kistaubayeva, Aida S. and Akimbekov, Nuraly S. and Digel, Ilya and Zhubanova, Azhar A.}, title = {Performance of Bio-Composite Carbonized Materials in Probiotic Applications}, series = {World Academy of Science, Engineering and Technology International Journal of Biotechnology and Bioengineering}, volume = {7}, booktitle = {World Academy of Science, Engineering and Technology International Journal of Biotechnology and Bioengineering}, number = {7}, pages = {685 -- 689}, year = {2013}, language = {en} } @article{ScholzRomagnoliDachwaldetal.2011, author = {Scholz, Christina and Romagnoli, Daniele and Dachwald, Bernd and Theil, Stephan}, title = {Performance analysis of an attitude control system for solar sails using sliding masses}, series = {Advances in Space Research}, volume = {48}, journal = {Advances in Space Research}, number = {11}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0273-1177}, pages = {1822 -- 1835}, year = {2011}, language = {en} } @article{VantStaatBaroud2008, author = {Vant, Christianne and Staat, Manfred and Baroud, Gamal}, title = {Percutaneous Vertebroplasty: A Review of Two Intraoperative Complications}, series = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)}, journal = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-540-75408-4}, pages = {527 -- 539}, year = {2008}, language = {en} } @inproceedings{BhattaraiStaat2018, author = {Bhattarai, Aroj and Staat, Manfred}, title = {Pectopexy to repair vaginal vault prolapse: a finite element approach}, series = {Proceedings CMBBE 2018}, booktitle = {Proceedings CMBBE 2018}, editor = {Fernandes, P.R. and Tavares, J. M.}, year = {2018}, abstract = {The vaginal prolapse after hysterectomy (removal of the uterus) is often associated with the prolapse of the vaginal vault, rectum, bladder, urethra or small bowel. Minimally invasive surgery such as laparoscopic sacrocolpopexy and pectopexy are widely performed for the treatment of the vaginal prolapse with weakly supported vaginal vault after hysterectomy using prosthetic mesh implants to support (or strengthen) lax apical ligaments. Implants of different shape, size and polymers are selected depending on the patient's anatomy and the surgeon's preference. In this computational study on pectopexy, DynaMesh®-PRP soft, GYNECARE GYNEMESH® PS Nonabsorbable PROLENE® soft and Ultrapro® are tested in a 3D finite element model of the female pelvic floor. The mesh model is implanted into the extraperitoneal space and sutured to the vaginal stump with a bilateral fixation to the iliopectineal ligament at both sides. Numerical simulations are conducted at rest, after surgery and during Valsalva maneuver with weakened tissues modeled by reduced tissue stiffness. Tissues and prosthetic meshes are modeled as incompressible, isotropic hyperelastic materials. The positions of the organs are calculated with respect to the pubococcygeal line (PCL) for female pelvic floor at rest, after repair and during Valsalva maneuver using the three meshes.}, language = {en} } @article{SpietzSproewitzSeefeldtetal.2021, author = {Spietz, Peter and Spr{\"o}witz, Tom and Seefeldt, Patric and Grundmann, Jan Thimo and Jahnke, Rico and Mikschl, Tobias and Mikulz, Eugen and Montenegro, Sergio and Reershemius, Siebo and Renger, Thomas and Ruffer, Michael and Sasaki, Kaname and Sznajder, Maciej and T{\´o}th, Norbert and Ceriotti, Matteo and Dachwald, Bernd and Macdonald, Malcolm and McInnes, Colin and Seboldt, Wolfgang and Quantius, Dominik and Bauer, Waldemar and Wiedemann, Carsten and Grimm, Christian D. and Hercik, David and Ho, Tra-Mi and Lange, Caroline and Schmitz, Nicole}, title = {Paths not taken - The Gossamer roadmap's other options}, series = {Advances in Space Research}, volume = {67}, journal = {Advances in Space Research}, number = {9}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0273-1177}, doi = {10.1016/j.asr.2021.01.044}, pages = {2912 -- 2956}, year = {2021}, language = {en} } @phdthesis{Kotliar2012, author = {Kotliar, Konstantin}, title = {Pathophysiologische Beurteilung und h{\"a}modynamische Analyse von mikrostrukturellen Ver{\"a}nderungen des retinalen Gef{\"a}ßl{\"a}ngsschnittsprofils}, pages = {328 S.}, year = {2012}, language = {ru} } @article{KohlerKirschnerHermannsStaatetal.2018, author = {Kohler, Annette and Kirschner-Hermanns, Ruth and Staat, Manfred and Brehmer, Bernhard}, title = {Pathogenese, funktionelle und anatomische Aspekte der weiblichen Belastungsinkontinenz}, series = {Aktuelle Urologie}, volume = {49}, journal = {Aktuelle Urologie}, number = {1}, publisher = {Thieme}, address = {Stuttgart}, issn = {1438-8820}, doi = {10.1055/s-0043-120616}, pages = {47 -- 51}, year = {2018}, abstract = {Der vorliegende Artikel fokussiert sich auf die weibliche Belastungsinkontinenz als Insuffizienz der Speicherfunktion der Blase, auch wenn im klinischen Alltag die Harninkontinenz der Frau h{\"a}ufig verschiedene Ursachen hat und insbesondere eine Belastungsinkontinenz im Alter und bei neurologischer Komorbidit{\"a}t nur selten isoliert vorkommt. Das kleine Becken der Frau ist sowohl als Funktions- als auch als strukturelle Einheit zu betrachten. Dabei unterliegen bei der Frau Blase, Harnr{\"o}hre, Geb{\"a}rmutter und Enddarm sowie die muskul{\"a}ren und ligament{\"o}sen Strukturen des kleinen Beckens durch Fertilit{\"a}tsphase, m{\"o}gliche Schwangerschaften, Geburten und Menopausen-Phase, {\"u}ber das „normale Altern" hinaus, gravierenden Ver{\"a}nderungen. This article focuses on female stress incontinence in the form of pelvic floor dysfunction and urethral sphincter deficiency, although isolated stress incontinence accounts for less than half of all incontinence cases. Especially in women of old age and those with neurological comorbidities, the causes of incontinence are mostly multifactorial. Also it has to be considered that the female bladder, urethra, uterus and rectum as well as the muscular and ligamentous structures of the female pelvis minor are affected by phases of fertility, possible pregnancies, births and menopause in addition to the normal ageing process.}, language = {de} } @article{DachwaldMengaliQuartaetal.2006, author = {Dachwald, Bernd and Mengali, Giovanni and Quarta, Alessandrao A. and Macdonald, Malcolm}, title = {Parametric Model and Optimal Control of Solar Sails with Optical Degradation}, series = {Journal of guidance, control, and dynamics. 29 (2006), H. 5}, journal = {Journal of guidance, control, and dynamics. 29 (2006), H. 5}, isbn = {0162-3192}, pages = {1170 -- 1178}, year = {2006}, language = {en} } @article{SponagelBaroudSteffenetal.2002, author = {Sponagel, Stefan and Baroud, G. and Steffen, T. and Wu, J.}, title = {Parameter identification for cement infiltration of osteoporotic bone}, series = {Poromechanics II : Proceedings of the Second Biot Conference on Poromechanics Grenoble, France 26 - 28 August 2002 / ed. by J.-L. Auriault ...}, journal = {Poromechanics II : Proceedings of the Second Biot Conference on Poromechanics Grenoble, France 26 - 28 August 2002 / ed. by J.-L. Auriault ...}, publisher = {Balkema}, address = {Lisse [u.a.]}, isbn = {90-5809-394-8}, pages = {55 -- 58}, year = {2002}, language = {en} } @article{RauschHarbrechtKahmannetal.2020, author = {Rausch, Valentin and Harbrecht, Andreas and Kahmann, Stephanie Lucina and Fenten, Thomas and Jovanovic, Nebojsa and Hackl, Michael and M{\"u}ller, Lars P. and Staat, Manfred and Wegmann, Kilian}, title = {Osteosynthesis of Phalangeal Fractures: Biomechanical Comparison of Kirschner Wires, Plates, and Compression Screws}, series = {The Journal of Hand Surgery}, volume = {45}, journal = {The Journal of Hand Surgery}, number = {10}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0363-5023}, doi = {10.1016/j.jhsa.2020.04.010}, pages = {987.e1 -- 987.e8}, year = {2020}, abstract = {Purpose The aim of this study was to compare several osteosynthesis techniques (intramedullary headless compression screws, T-plates, and Kirschner wires) for distal epiphyseal fractures of proximal phalanges in a human cadaveric model. Methods A total of 90 proximal phalanges from 30 specimens (index, ring, and middle fingers) were used for this study. After stripping off all soft tissue, a transverse distal epiphyseal fracture was simulated at the proximal phalanx. The 30 specimens were randomly assigned to 1 fixation technique (30 per technique), either a 3.0-mm intramedullary headless compression screw, locking plate fixation with a 2.0-mm T-plate, or 2 oblique 1.0-mm Kirschner wires. Displacement analysis (bending, distraction, and torsion) was performed using optical tracking of an applied random speckle pattern after osteosynthesis. Biomechanical testing was performed with increasing cyclic loading and with cyclic load to failure using a biaxial torsion-tension testing machine. Results Cannulated intramedullary compression screws showed significantly less displacement at the fracture site in torsional testing. Furthermore, screws were significantly more stable in bending testing. Kirschner wires were significantly less stable than plating or screw fixation in any cyclic load to failure test setup. Conclusions Intramedullary compression screws are a highly stable alternative in the treatment of transverse distal epiphyseal phalangeal fractures. Kirschner wires seem to be inferior regarding displacement properties and primary stability. Clinical relevance Fracture fixation of phalangeal fractures using plate osteosynthesis may have the advantage of a very rigid reduction, but disadvantages such as stiffness owing to the more invasive surgical approach and soft tissue irritation should be taken into account. Headless compression screws represent a minimally invasive choice for fixation with good biomechanical properties.}, language = {en} } @article{SadykovDigelTemizArtmannetal.2009, author = {Sadykov, Rustam and Digel, Ilya and Temiz Artmann, Ayseg{\"u}l and Porst, Dariusz and Linder, Peter and Kayser, Peter and Artmann, Gerhard and Savitskaya, Irina and Zhubanova, Azhar}, title = {Oral lead exposure induces dysbacteriosis in rats}, series = {Journal of Occupational Health. 51 (2009) (2009), H. 1}, journal = {Journal of Occupational Health. 51 (2009) (2009), H. 1}, isbn = {1348-9585}, pages = {64 -- 73}, year = {2009}, language = {en} } @article{DachwaldCarnelliVasile2007, author = {Dachwald, Bernd and Carnelli, I. and Vasile, M.}, title = {Optimizing low-thrust gravity assist interplanetary trajectories using evolutionary neurocontrollers / I. Carnelli ; B. Dachwald ; M. Vasile}, series = {IEEE Congress on Evolutionary Computation, 2007 : CEC 2007 ; 25 - 28 September 2007, Singapore}, journal = {IEEE Congress on Evolutionary Computation, 2007 : CEC 2007 ; 25 - 28 September 2007, Singapore}, publisher = {IEEE Service Center}, address = {Piscataway, NJ}, isbn = {978-1-424-41339-3}, pages = {965 -- 972}, year = {2007}, language = {en} } @article{Dachwald2005, author = {Dachwald, Bernd}, title = {Optimization of very-low-thrust trajectories using evolutionary neurocontrol}, series = {Acta Astronautica. 57 (2005), H. 2-8}, journal = {Acta Astronautica. 57 (2005), H. 2-8}, isbn = {0094-5765}, pages = {175 -- 185}, year = {2005}, language = {en} } @article{Dachwald2005, author = {Dachwald, Bernd}, title = {Optimization of very-low-thrust trajectories using evolutionary neurocontrol}, series = {Acta Astronautica}, volume = {57}, journal = {Acta Astronautica}, number = {2-8}, publisher = {Elsevier}, address = {Amsterdam [u.a.]}, isbn = {1879-2030}, pages = {175 -- 185}, year = {2005}, abstract = {Searching optimal interplanetary trajectories for low-thrust spacecraft is usually a difficult and time-consuming task that involves much experience and expert knowledge in astrodynamics and optimal control theory. This is because the convergence behavior of traditional local optimizers, which are based on numerical optimal control methods, depends on an adequate initial guess, which is often hard to find, especially for very-low-thrust trajectories that necessitate many revolutions around the sun. The obtained solutions are typically close to the initial guess that is rarely close to the (unknown) global optimum. Within this paper, trajectory optimization problems are attacked from the perspective of artificial intelligence and machine learning. Inspired by natural archetypes, a smart global method for low-thrust trajectory optimization is proposed that fuses artificial neural networks and evolutionary algorithms into so-called evolutionary neurocontrollers. This novel method runs without an initial guess and does not require the attendance of an expert in astrodynamics and optimal control theory. This paper details how evolutionary neurocontrol works and how it could be implemented. The performance of the method is assessed for three different interplanetary missions with a thrust to mass ratio <0.15mN/kg (solar sail and nuclear electric).}, language = {en} } @article{JungMuellerStaat2019, author = {Jung, Alexander and M{\"u}ller, Wolfram and Staat, Manfred}, title = {Optimization of the flight technique in ski jumping: the influence of wind}, number = {Early view}, publisher = {Elsevier}, address = {Amsterdam}, doi = {10.1016/j.jbiomech.2019.03.023}, year = {2019}, language = {en} } @inproceedings{JungStaatMueller2014, author = {Jung, Alexander and Staat, Manfred and M{\"u}ller, Wolfram}, title = {Optimization of the flight style in ski jumping}, series = {11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20 - 25, 2014, Barcelona}, booktitle = {11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20 - 25, 2014, Barcelona}, editor = {Onate, E.}, organization = {World Congress on Computational Mechanics <11, 2014, Barcelona>}, pages = {799 -- 810}, year = {2014}, language = {en} } @article{DachwaldOhndorfGill2009, author = {Dachwald, Bernd and Ohndorf, A. and Gill, E.}, title = {Optimization of low-thrust Earth-Moon transfers using evolutionary neurocontrol / Ohndorf, A. ; Dachwald, B. ; Gill, E.}, series = {IEEE Congress on Evolutionary Computation, 2009. CEC '09.}, journal = {IEEE Congress on Evolutionary Computation, 2009. CEC '09.}, isbn = {978-1-4244-2958-5}, pages = {358 -- 364}, year = {2009}, language = {en} } @article{Dachwald2004, author = {Dachwald, Bernd}, title = {Optimization of Interplanetary Solar Sailcraft Trajectories Using Evolutionary Neurocontrol}, series = {Journal of guidance, control, and dynamics. 27 (2004), H. 1}, journal = {Journal of guidance, control, and dynamics. 27 (2004), H. 1}, isbn = {0162-3192}, pages = {66 -- 72}, year = {2004}, language = {en} } @article{DachwaldSeboldt2002, author = {Dachwald, Bernd and Seboldt, W.}, title = {Optimization of Interplanetary Rendezvous Trajectories for Solar Sailcraft Using a Neurocontroller}, series = {A collection of technical papers / AIAA Astrodynamics Specialist Conference : Monterey, California, 5 - 8 August 2002. - Vol. 2}, journal = {A collection of technical papers / AIAA Astrodynamics Specialist Conference : Monterey, California, 5 - 8 August 2002. - Vol. 2}, publisher = {American Institute of Aeronautics and Astronautics}, address = {Reston, Va.}, isbn = {1-56347-549-9}, pages = {1263 -- 1270}, year = {2002}, language = {en} } @inproceedings{SchoutetensDachwaldHeiligers2021, author = {Schoutetens, Frederic and Dachwald, Bernd and Heiligers, Jeannette}, title = {Optimisation of photon-sail trajectories in the alpha-centauri system using evolutionary neurocontrol}, series = {8th ICATT (International Conference on Astrodynamics Tools and Techniques) 23 - 25 June 2021, Virtual}, booktitle = {8th ICATT (International Conference on Astrodynamics Tools and Techniques) 23 - 25 June 2021, Virtual}, pages = {1 -- 15}, year = {2021}, abstract = {With the increased interest for interstellar exploration after the discovery of exoplanets and the proposal by Breakthrough Starshot, this paper investigates the optimisation of photon-sail trajectories in Alpha Centauri. The prime objective is to find the optimal steering strategy for a photonic sail to get captured around one of the stars after a minimum-time transfer from Earth. By extending the idea of the Breakthrough Starshot project with a deceleration phase upon arrival, the mission's scientific yield will be increased. As a secondary objective, transfer trajectories between the stars and orbit-raising manoeuvres to explore the habitable zones of the stars are investigated. All trajectories are optimised for minimum time of flight using the trajectory optimisation software InTrance. Depending on the sail technology, interstellar travel times of 77.6-18,790 years can be achieved, which presents an average improvement of 30\% with respect to previous work. Still, significant technological development is required to reach and be captured in the Alpha-Centauri system in less than a century. Therefore, a fly-through mission arguably remains the only option for a first exploratory mission to Alpha Centauri, but the enticing results obtained in this work provide perspective for future long-residence missions to our closest neighbouring star system.}, language = {en} } @article{DachwaldOhndorfSeboldt2005, author = {Dachwald, Bernd and Ohndorf, A. and Seboldt, W.}, title = {Optimierung der Lageregelung von Raumfahrzeugen mit Niedrigschubantrieb mittels evolution{\"a}rer neuronaler Regler / A. Ohndorf ; B. Dachwald ; W. Seboldt}, series = {Deutscher Luft- und Raumfahrtkongress 2005 : Friedrichshafen, 26. bis 29. September 2005, Motto: Luft- und Raumfahrt - Grenzen {\"u}berwinden, Horizonte erweitern / Deutsche Gesellschaft f{\"u}r Luft- und Raumfahrt - Lilienthal-Oberth e.V. (DGLR). [Red.: Peter Brandt (verantwortlich)]. Bd. 3. - (Jahrbuch ... der Deutschen Gesellschaft f{\"u}r Luft- und Raumfahrt}, journal = {Deutscher Luft- und Raumfahrtkongress 2005 : Friedrichshafen, 26. bis 29. September 2005, Motto: Luft- und Raumfahrt - Grenzen {\"u}berwinden, Horizonte erweitern / Deutsche Gesellschaft f{\"u}r Luft- und Raumfahrt - Lilienthal-Oberth e.V. (DGLR). [Red.: Peter Brandt (verantwortlich)]. Bd. 3. - (Jahrbuch ... der Deutschen Gesellschaft f{\"u}r Luft- und Raumfahrt}, publisher = {DGLR}, address = {Bonn}, pages = {1971 -- 1978}, year = {2005}, language = {de} } @article{Dachwald2005, author = {Dachwald, Bernd}, title = {Optimal Solar Sail Trajectories for Missions to the Outer Solar System}, series = {Journal of guidance, control, and dynamics. 28 (2005), H. 6}, journal = {Journal of guidance, control, and dynamics. 28 (2005), H. 6}, isbn = {0162-3192}, pages = {1187 -- 1193}, year = {2005}, language = {en} } @article{Dachwald2004, author = {Dachwald, Bernd}, title = {Optimal Solar Sail Trajectories for Missions to the Outer Solar System}, series = {22nd AIAA Applied Aerodynamics Conference and Exhibit - AIAA/AAS Astrodynamics Specialist Conference and Exhibit - AIAA Guidance, Navigation, and Control Conference and Exhibit - AIAA Modeling and Simulation Technologies Conference and Exhibit - AIAA Atmospheric Flight Mechanics Conference and Exhibit : 16 - 19 August 2004, Providence, Rhode Island / American Institute of Aeronautics and Astronautics. - (AIAA meeting papers on disc ; 2004,14-15)}, journal = {22nd AIAA Applied Aerodynamics Conference and Exhibit - AIAA/AAS Astrodynamics Specialist Conference and Exhibit - AIAA Guidance, Navigation, and Control Conference and Exhibit - AIAA Modeling and Simulation Technologies Conference and Exhibit - AIAA Atmospheric Flight Mechanics Conference and Exhibit : 16 - 19 August 2004, Providence, Rhode Island / American Institute of Aeronautics and Astronautics. - (AIAA meeting papers on disc ; 2004,14-15)}, publisher = {American Inst. of Aeronautics and Astronautics}, address = {Reston, Va.}, pages = {2 CD-ROMs}, year = {2004}, language = {en} } @article{HorbachStaat2018, author = {Horbach, Andreas and Staat, Manfred}, title = {Optical strain measurement for the modeling of surgical meshes and their porosity}, series = {Current Directions in Biomedical Engineering}, volume = {Band 4}, journal = {Current Directions in Biomedical Engineering}, number = {1}, publisher = {De Gruyter}, address = {Berlin}, issn = {2364-5504}, doi = {10.1515/cdbme-2018-0045}, pages = {181 -- 184}, year = {2018}, abstract = {The porosity of surgical meshes makes them flexible for large elastic deformation and establishes the healing conditions of good tissue in growth. The biomechanic modeling of orthotropic and compressible materials requires new materials models and simulstaneoaus fit of deformation in the load direction as well as trannsversely to to load. This nonlinear modeling can be achieved by an optical deformation measurement. At the same time the full field deformation measurement allows the dermination of the change of porosity with deformation. Also the socalled effective porosity, which has been defined to asses the tisssue interatcion with the mesh implants, can be determined from the global deformation of the surgical meshes.}, language = {en} } @inproceedings{DachwaldMengaliQuartaetal.2007, author = {Dachwald, Bernd and Mengali, Giovanni and Quarta, Alessandro A and Macdonald, Malcolm and McInnes, Colin R}, title = {Optical solar sail degradation modelling}, series = {1st International Symposium on Solar Sailing}, booktitle = {1st International Symposium on Solar Sailing}, pages = {1 -- 27}, year = {2007}, abstract = {We propose a simple parametric OSSD model that describes the variation of the sail film's optical coefficients with time, depending on the sail film's environmental history, i.e., the radiation dose. The primary intention of our model is not to describe the exact behavior of specific film-coating combinations in the real space environment, but to provide a more general parametric framework for describing the general optical degradation behavior of solar sails.}, language = {en} } @article{MiciliValterOflazetal.2013, author = {Micili, Serap C. and Valter, Markus and Oflaz, Hakan and Ozogul, Candan and Linder, Peter and F{\"o}ckler, Nicole and Artmann, Gerhard and Digel, Ilya and Temiz Artmann, Ayseg{\"u}l}, title = {Optical coherence tomography : a potential tool to predict premature rupture of fetal membranes}, series = {Proceedings of the Institution of Mechanical Engineers. Part H : Journal of engineering in medicine}, volume = {Vol. 227}, journal = {Proceedings of the Institution of Mechanical Engineers. Part H : Journal of engineering in medicine}, number = {No. 4}, publisher = {Sage}, address = {London}, issn = {0046-2039 (Print) ; 2041-3033 (E-Journal)}, pages = {393 -- 401}, year = {2013}, language = {en} } @inproceedings{BaaderKellerLehmannetal.2019, author = {Baader, Fabian and Keller, Denis and Lehmann, Raphael and Gerber, Lukas and Reiswich, Martin and Dachwald, Bernd and F{\"o}rstner, Roger}, title = {Operating melting probes for ice penetration under sublimation conditions and in reduced gravity on a sounding rocket}, series = {Proceedings of the 24th ESA Symposium on European Rocket and Balloon Programmes and related Research}, booktitle = {Proceedings of the 24th ESA Symposium on European Rocket and Balloon Programmes and related Research}, issn = {0379-6566}, pages = {8 Seiten}, year = {2019}, language = {en} } @article{YangKriechbaumerAlbrachtetal.2015, author = {Yang, Peng-Fei and Kriechbaumer, Andreas and Albracht, Kirsten and Sanno, Maximilian and Ganse, Bergita and Koy, Timmo and Shang, Peng and Br{\"u}ggemann, Gert-Peter and M{\"u}ller, Lars Peter and Rittweger, J{\"o}rn}, title = {On the relationship between tibia torsional deformation and regional muscle contractions in habitual human exercises in vivo}, series = {Journal of Biomechanics}, volume = {48}, journal = {Journal of Biomechanics}, number = {3}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0021-9290}, doi = {10.1016/j.jbiomech.2014.12.031}, pages = {456 -- 464}, year = {2015}, language = {en} } @incollection{Kotliar2021, author = {Kotliar, Konstantin}, title = {Ocular rigidity: clinical approach}, series = {Ocular Rigidity, Biomechanics and Hydrodynamics of the Eye}, booktitle = {Ocular Rigidity, Biomechanics and Hydrodynamics of the Eye}, editor = {Pallikaris, I. and Tsilimbaris, M. K. and Dastiridou, A. I.}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-64422-2}, doi = {10.1007/978-3-030-64422-2_2}, pages = {15 -- 43}, year = {2021}, abstract = {The term ocular rigidity is widely used in clinical ophthalmology. Generally it is assumed as a resistance of the whole eyeball to mechanical deformation and relates to biomechanical properties of the eye and its tissues. Basic principles and formulas for clinical tonometry, tonography and pulsatile ocular blood flow measurements are based on the concept of ocular rigidity. There is evidence for altered ocular rigidity in aging, in several eye diseases and after eye surgery. Unfortunately, there is no consensual view on ocular rigidity: it used to make a quite different sense for different people but still the same name. Foremost there is no clear consent between biomechanical engineers and ophthalmologists on the concept. Moreover ocular rigidity is occasionally characterized using various parameters with their different physical dimensions. In contrast to engineering approach, clinical approach to ocular rigidity claims to characterize the total mechanical response of the eyeball to its deformation without any detailed considerations on eye morphology or material properties of its tissues. Further to the previous chapter this section aims to describe clinical approach to ocular rigidity from the perspective of an engineer in an attempt to straighten out this concept, to show its advantages, disadvantages and various applications.}, language = {en} } @article{KotliarDrozdovaShamshinova2006, author = {Kotliar, Konstantin and Drozdova, G. A. and Shamshinova, A. M.}, title = {Ocular hemodinamics and contemporary methods of its assessment.
 Part I. Ocular blood circulation and its quantitative estimation}, series = {National journal Glaucoma}, volume = {Vol. 5}, journal = {National journal Glaucoma}, number = {No. 3}, issn = {2078-4104}, pages = {62 -- 73}, year = {2006}, language = {ru} } @article{KotliarDrozdovaShamshinova2007, author = {Kotliar, Konstantin and Drozdova, G. A. and Shamshinova, A. M.}, title = {Ocular hemodinamics and contemporary methods of its assessment. Part III. Non-invasive methods of assessment of ocular blood flow. 2. Static and dynamic assessment of retinal vessel reaction to stimuli}, series = {National Journal Glaucoma}, volume = {Vol. 6}, journal = {National Journal Glaucoma}, number = {No. 2}, issn = {2078-4104}, pages = {64 -- 71}, year = {2007}, language = {ru} } @article{KotliarDrozdovaShamshinova2007, author = {Kotliar, Konstantin and Drozdova, G. A. and Shamshinova, A. M.}, title = {Ocular hemodinamics and contemporary methods of its assessment. Part III. Non-invasive methods of assessment of ocular blood flow. 1. Assessment of blood cell velocities and flow rates in intraocular vessels and vascular beds}, series = {Journal of Glaucoma}, volume = {Vol. 6}, journal = {Journal of Glaucoma}, number = {1}, issn = {2078-4104}, pages = {61 -- 68}, year = {2007}, language = {ru} } @article{KotliarDrozdovaShamshinova2006, author = {Kotliar, Konstantin and Drozdova, G. A. and Shamshinova, A. M.}, title = {Ocular hemodinamics and contemporary methods of its assessment. Part II. Invasive methods of assessment of ocular blood flow}, series = {National Journal Glaucoma}, volume = {Vol. 5}, journal = {National Journal Glaucoma}, number = {No. 4}, issn = {2078-4104}, pages = {37 -- 49}, year = {2006}, language = {ru} } @inproceedings{DuongNguyenStaat2012, author = {Duong, Minh Tuan and Nguyen, Nhu Huynh and Staat, Manfred}, title = {Numerical stability enhancement of modeling hyperelastic materials}, series = {Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)}, booktitle = {Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)}, editor = {Eberhardsteiner, J.}, year = {2012}, language = {en} } @article{BehbahaniTranJockenhoeveletal.2011, author = {Behbahani, Mehdi and Tran, L. and Jockenh{\"o}vel, S. and Behr, M. and Mottaghy, K.}, title = {Numerical prediction of thrombocyte reactions for application to a vascular flow model}, series = {British Journal of Surgery}, volume = {98}, journal = {British Journal of Surgery}, number = {S5}, publisher = {Oxford University Press}, address = {Oxford}, isbn = {1365-2168}, pages = {S17}, year = {2011}, language = {en} } @article{BehbahaniProbstMaietal.2010, author = {Behbahani, Mehdi and Probst, M. and Mai, A. and Behr, M. and Tran, L. and Vonderstein, K. and Mottaghy, K.}, title = {Numerical Prediction of Blood Damage in Biomedical Devices}, year = {2010}, language = {en} } @article{BehbahaniMaiWalugaetal.2010, author = {Behbahani, Mehdi and Mai, A. and Waluga, C. and Bergmann, B. and Tran, L. and Vonderstein, K. and Behr, M. and Mottaghy, K.}, title = {Numerical Modeling of Flow-Related Thrombus Formation under Physiological and Non-Physiological Flow Conditions}, series = {Acta Physiologica}, volume = {198}, journal = {Acta Physiologica}, number = {Supplement 677}, isbn = {1748-1716}, pages = {185}, year = {2010}, language = {en} } @book{StaatHeitzer2003, author = {Staat, Manfred and Heitzer, Michael}, title = {Numerical methods for limit and shakedown analysis. Deterministic and probabilistic problems.}, publisher = {John von Neumann Institute for Computing (NIC)}, address = {J{\"u}lich}, isbn = {3-00-010001-6}, pages = {2, xiii, 282 Seiten}, year = {2003}, language = {en} } @inproceedings{MarinovaKerroumiLintermannetal.2016, author = {Marinova, V. and Kerroumi, I. and Lintermann, A. and G{\"o}bbert, J.H. and Moulinec, C. and Rible, S. and Fournier, Y. and Behbahani, Mehdi}, title = {Numerical Analysis of the FDA Centrifugal Blood Pump}, series = {NIC Symposium 2016}, booktitle = {NIC Symposium 2016}, isbn = {978-3-95806-109-5}, pages = {355 -- 364}, year = {2016}, language = {de} } @article{QuittmannMeskemperAlbrachtetal.2020, author = {Quittmann, Oliver J. and Meskemper, Joshua and Albracht, Kirsten and Abel, Thomas and Foitschik, Tina and Str{\"u}der, Heiko K.}, title = {Normalising surface EMG of ten upper-extremity muscles in handcycling: Manual resistance vs. sport-specific MVICs}, series = {Journal of Electromyography and Kinesiology}, volume = {51}, journal = {Journal of Electromyography and Kinesiology}, number = {Article 102402}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1050-6411}, doi = {10.1016/j.jelekin.2020.102402}, year = {2020}, abstract = {Muscular activity in terms of surface electromyography (sEMG) is usually normalised to maximal voluntary isometric contractions (MVICs). This study aims to compare two different MVIC-modes in handcycling and examine the effect of moving average window-size. Twelve able-bodied male competitive triathletes performed ten MVICs against manual resistance and four sport-specific trials against fixed cranks. sEMG of ten muscles [M. trapezius (TD); M. pectoralis major (PM); M. deltoideus, Pars clavicularis (DA); M. deltoideus, Pars spinalis (DP); M. biceps brachii (BB); M. triceps brachii (TB); forearm flexors (FC); forearm extensors (EC); M. latissimus dorsi (LD) and M. rectus abdominis (RA)] was recorded and filtered using moving average window-sizes of 150, 200, 250 and 300 ms. Sport-specific MVICs were higher compared to manual resistance for TB, DA, DP and LD, whereas FC, TD, BB and RA demonstrated lower values. PM and EC demonstrated no significant difference between MVIC-modes. Moving average window-size had no effect on MVIC outcomes. MVIC-mode should be taken into account when normalised sEMG data are illustrated in handcycling. Sport-specific MVICs seem to be suitable for some muscles (TB, DA, DP and LD), but should be augmented by MVICs against manual/mechanical resistance for FC, TD, BB and RA.}, language = {en} } @article{DashevskyLanzlKotliar2011, author = {Dashevsky, Alexey V. and Lanzl, Ines M. and Kotliar, Konstantin}, title = {Non-penetrating intracanalicular partial trabeculectomy via the ostia of Schlemm's canal}, series = {Graefe's Archive for Clinical and Experimental Ophthalmology}, volume = {249}, journal = {Graefe's Archive for Clinical and Experimental Ophthalmology}, number = {4}, publisher = {Springer}, address = {Berlin}, issn = {0721-832x}, pages = {565 -- 573}, year = {2011}, language = {en} } @article{AlbannaKotliarLuekeetal.2018, author = {Albanna, Walid and Kotliar, Konstantin and L{\"u}ke, Jan Niklas and Alpdogan, Serdar and Conzen, Catharina and Lindauer, Ute and Clusmann, Hans and Hescheler, J{\"u}rgen and Vilser, Walthard and Schneider, Toni and Schubert, Gerrit Alexander}, title = {Non-invasive evaluation of neurovascular coupling in the murine retina by dynamic retinal vessel analysis}, series = {Plos one}, volume = {13}, journal = {Plos one}, number = {10}, publisher = {PLOS}, address = {San Francisco}, doi = {10.1371/journal.pone.0204689}, pages = {e0204689}, year = {2018}, abstract = {Background Impairment of neurovascular coupling (NVC) was recently reported in the context of subarachnoid hemorrhage and may correlate with disease severity and outcome. However, previous techniques to evaluate NVC required invasive procedures. Retinal vessels may represent an alternative option for non-invasive assessment of NVC. Methods A prototype of an adapted retinal vessel analyzer was used to assess retinal vessel diameter in mice. Dynamic vessel analysis (DVA) included an application of monochromatic flicker light impulses in predefined frequencies for evaluating NVC. All retinae were harvested after DVA and electroretinograms were performed. Results A total of 104 retinal scans were conducted in 21 male mice (90 scans). Quantitative arterial recordings were feasible only in a minority of animals, showing an emphasized reaction to flicker light impulses (8 mice; 14 scans). A characteristic venous response to flicker light, however, could observed in the majority of animals. Repeated measurements resulted in a significant decrease of baseline venous diameter (7 mice; 7 scans, p < 0.05). Ex-vivo electroretinograms, performed after in-vivo DVA, demonstrated a significant reduction of transretinal signaling in animals with repeated DVA (n = 6, p < 0.001). Conclusions To the best of our knowledge, this is the first non-invasive study assessing murine retinal vessel response to flicker light with characteristic changes in NVC. The imaging system can be used for basic research and enables the investigation of retinal vessel dimension and function in control mice and genetically modified animals.}, language = {en} } @article{AlbannaConzenWeissetal.2021, author = {Albanna, Walid and Conzen, Catharina and Weiss, Miriam and Seyfried, Katharina and Kotliar, Konstantin and Schmidt, Tobias Philip and Kuerten, David and Hescheler, J{\"u}rgen and Bruecken, Anne and Schmidt-Trucks{\"a}ss, Arno and Neumaier, Felix and Wiesmann, Martin and Clusmann, Hans and Schubert, Gerrit Alexander}, title = {Non-invasive assessment of neurovascular coupling after aneurysmal subarachnoid hemorrhage: a prospective observational trial using retinal vessel analysis}, series = {Frontiers in Neurology}, volume = {12}, journal = {Frontiers in Neurology}, number = {12}, issn = {1664-2295}, doi = {10.3389/fneur.2021.690183}, pages = {1 -- 15}, year = {2021}, abstract = {Delayed cerebral ischemia (DCI) is a common complication after aneurysmal subarachnoid hemorrhage (aSAH) and can lead to infarction and poor clinical outcome. The underlying mechanisms are still incompletely understood, but animal models indicate that vasoactive metabolites and inflammatory cytokines produced within the subarachnoid space may progressively impair and partially invert neurovascular coupling (NVC) in the brain. Because cerebral and retinal microvasculature are governed by comparable regulatory mechanisms and may be connected by perivascular pathways, retinal vascular changes are increasingly recognized as a potential surrogate for altered NVC in the brain. Here, we used non-invasive retinal vessel analysis (RVA) to assess microvascular function in aSAH patients at different times after the ictus.}, language = {en} } @article{BaumannSchwarzKotliaretal.2009, author = {Baumann, Marcus and Schwarz, Sonja and Kotliar, Konstantin and Eynatten, Maximilian von and Trucksaess, Arno and Burckhardt, Klaus and Lutz, Jens and Heemann, Uwe and Lanzl, Ines}, title = {Non-diabetic chronic kidney disease influences retinal microvasculature}, series = {Kidney and Blood Pressure Research}, volume = {32}, journal = {Kidney and Blood Pressure Research}, number = {6}, publisher = {-}, isbn = {1423-0143}, pages = {428 -- 433}, year = {2009}, language = {en} } @article{TemizArtmannLinderKayseretal.2005, author = {Temiz Artmann, Ayseg{\"u}l and Linder, Peter and Kayser, Peter and Digel, Ilya}, title = {NMR in vitro effects on proliferation, apoptosis, and viability of human chondrocytes and osteoblasts}, series = {Methods and findings in Experimental and Clinical Pharmacology. 27 (2005), H. 6}, journal = {Methods and findings in Experimental and Clinical Pharmacology. 27 (2005), H. 6}, isbn = {0379-0355}, pages = {391 -- 394}, year = {2005}, language = {en} } @article{StaatTrenzLohmannetal.2012, author = {Staat, Manfred and Trenz, Eva and Lohmann, Philipp and Frotscher, Ralf and Klinge, Uwe and Tabaza, Ruth and Kirschner-Hermanns, Ruth}, title = {New measurements to compare soft tissue anchoring systems in pelvic floor surgery}, series = {Journal of Biomedical Materials Research Part B: Applied Biomaterials}, volume = {100B}, journal = {Journal of Biomedical Materials Research Part B: Applied Biomaterials}, number = {4}, publisher = {Wiley}, address = {Hoboken, NJ}, issn = {1552-4981}, doi = {10.1002/jbm.b.32654}, pages = {924 -- 933}, year = {2012}, abstract = {Suburethral slings as well as different meshes are widely used treating stress urinary incontinence and prolaps in women. With the development of MiniSlings and special meshes using less alloplastic material anchorage systems become more important to keep devices in place and to put some tension especially on the MiniSlings. To date, there are many different systems of MiniSlings of different companies on the market which differ in the structure of the used meshes and anchors. A new objective measurement method to compare different properties of MiniSling systems (mesh and anchor) is presented in this article. Ballistic gelatine acts as soft tissue surrogate. Significant differences in parameters like pull-out strength of anchors or shrinkage of meshes under loading conditions have been determined. The form and size of the anchors as well as the structural stability of the meshes are decisive for a proper integration. The tested anchorings sytems showed markedly different mechanical function at their respective load bearing capacity. As the stable fixation of the device in tissue is a prerequisite for a permanet reinforcement, the proposed test system permits further optimisation of anchor and mesh devices to improve the success of the surgical treatment}, language = {en} } @article{NamAroraBehbahanietal.2010, author = {Nam, J. and Arora, D. and Behbahani, Mehdi and Probst, M. and Benkowski, R. and Behr, M. and Pasquali, M.}, title = {New computational method in hemolysis analysis for artificial heart pump}, year = {2010}, language = {en} } @article{KowalskiLinderZierkeetal.2016, author = {Kowalski, Julia and Linder, Peter and Zierke, S. and Wulfen, B. van and Clemens, J. and Konstantinidis, K. and Ameres, G. and Hoffmann, R. and Mikucki, J. and Tulaczyk, S. and Funke, O. and Blandfort, D. and Espe, Clemens and Feldmann, Marco and Francke, Gero and Hiecker, S. and Plescher, Engelbert and Sch{\"o}ngarth, Sarah and Dachwald, Bernd and Digel, Ilya and Artmann, Gerhard and Eliseev, D. and Heinen, D. and Scholz, F. and Wiebusch, C. and Macht, S. and Bestmann, U. and Reineking, T. and Zetzsche, C. and Schill, K. and F{\"o}rstner, R. and Niedermeier, H. and Szumski, A. and Eissfeller, B. and Naumann, U. and Helbing, K.}, title = {Navigation technology for exploration of glacier ice with maneuverable melting probes}, series = {Cold Regions Science and Technology}, journal = {Cold Regions Science and Technology}, number = {123}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0165-232X}, doi = {10.1016/j.coldregions.2015.11.006}, pages = {53 -- 70}, year = {2016}, abstract = {The Saturnian moon Enceladus with its extensive water bodies underneath a thick ice sheet cover is a potential candidate for extraterrestrial life. Direct exploration of such extraterrestrial aquatic ecosystems requires advanced access and sampling technologies with a high level of autonomy. A new technological approach has been developed as part of the collaborative research project Enceladus Explorer (EnEx). The concept is based upon a minimally invasive melting probe called the IceMole. The force-regulated, heater-controlled IceMole is able to travel along a curved trajectory as well as upwards. Hence, it allows maneuvers which may be necessary for obstacle avoidance or target selection. Maneuverability, however, necessitates a sophisticated on-board navigation system capable of autonomous operations. The development of such a navigational system has been the focal part of the EnEx project. The original IceMole has been further developed to include relative positioning based on in-ice attitude determination, acoustic positioning, ultrasonic obstacle and target detection integrated through a high-level sensor fusion. This paper describes the EnEx technology and discusses implications for an actual extraterrestrial mission concept.}, language = {en} } @inproceedings{O'HerasDigelTemizArtmann2009, author = {O\'Heras, Carlos and Digel, Ilya and Temiz Artmann, Ayseg{\"u}l}, title = {Nanostructured carbon-based column for LPS/protein adsorption : [abstract]}, year = {2009}, abstract = {The absence of a general method for endotoxin removal from liquid interfaces gives an opportunity to find new methods and materials to overcome this gap. Activated nanostructured carbon is a promising material that showed good adsorption properties due to its vast pore network and high surface area. The aim of this study is to find the adsorption rates for a carboneous material produced at different temperatures, as well as to reveal possible differences between the performance of the material for each of the adsorbates used during the study (hemoglobin, serum albumin and lipopolysaccharide, LPS).}, subject = {Kohlenstofffaser}, language = {en} }