@inproceedings{AmirBauckhageChircuetal.2022, author = {Amir, Malik and Bauckhage, Christian and Chircu, Alina and Czarnecki, Christian and Knopf, Christian and Piatkowski, Nico and Sultanow, Eldar}, title = {What can we expect from quantum (digital) twins?}, series = {Wirtschaftsinformatik 2022 Proceedings}, booktitle = {Wirtschaftsinformatik 2022 Proceedings}, publisher = {AIS Electronic Library (AISeL)}, pages = {1 -- 14}, year = {2022}, abstract = {Digital twins enable the modeling and simulation of real-world entities (objects, processes or systems), resulting in improvements in the associated value chains. The emerging field of quantum computing holds tremendous promise forevolving this virtualization towards Quantum (Digital) Twins (QDT) and ultimately Quantum Twins (QT). The quantum (digital) twin concept is not a contradiction in terms - but instead describes a hybrid approach that can be implemented using the technologies available today by combining classicalcomputing and digital twin concepts with quantum processing. This paperpresents the status quo of research and practice on quantum (digital) twins. It alsodiscuses their potential to create competitive advantage through real-timesimulation of highly complex, interconnected entities that helps companies better address changes in their environment and differentiate their products andservices.}, language = {en} } @article{PhilippEfthimiouPaganoetal.2022, author = {Philipp, Mohr and Efthimiou, Nikos and Pagano, Fiammetta and Kratochwil, Nicolaus and Pizzichemi, Marco and Tsoumpas, Charalampos and Auffray, Etiennette and Ziemons, Karl}, title = {Image reconstruction analysis for positron emission tomography with heterostructured scintillators}, series = {IEEE Transactions on Radiation and Plasma Medical Sciences}, volume = {7}, journal = {IEEE Transactions on Radiation and Plasma Medical Sciences}, number = {1}, publisher = {IEEE}, address = {New York, NY}, issn = {2469-7311}, doi = {10.1109/TRPMS.2022.3208615}, pages = {41 -- 51}, year = {2022}, abstract = {The concept of structure engineering has been proposed for exploring the next generation of radiation detectors with improved performance. A TOF-PET geometry with heterostructured scintillators with a pixel size of 3.0×3.1×15 mm3 was simulated using Monte Carlo. The heterostructures consisted of alternating layers of BGO as a dense material with high stopping power and plastic (EJ232) as a fast light emitter. The detector time resolution was calculated as a function of the deposited and shared energy in both materials on an event-by-event basis. While sensitivity was reduced to 32\% for 100 μm thick plastic layers and 52\% for 50 μm, the CTR distribution improved to 204±49 ps and 220±41 ps respectively, compared to 276 ps that we considered for bulk BGO. The complex distribution of timing resolutions was accounted for in the reconstruction. We divided the events into three groups based on their CTR and modeled them with different Gaussian TOF kernels. On a NEMA IQ phantom, the heterostructures had better contrast recovery in early iterations. On the other hand, BGO achieved a better contrast to noise ratio (CNR) after the 15th iteration due to the higher sensitivity. The developed simulation and reconstruction methods constitute new tools for evaluating different detector designs with complex time responses.}, language = {en} } @incollection{BauschatBennerKlingeetal.2022, author = {Bauschat, J.-Michael and Benner, Miriam and Klinge, Henner and Ziegler, Simon}, title = {Urbane Mobilit{\"a}t entdeckt die 3. Dimension}, series = {Transforming Mobility - What Next?}, booktitle = {Transforming Mobility - What Next?}, publisher = {Springer Gabler}, address = {Wiesbaden}, isbn = {978-3-658-36429-8}, doi = {10.1007/978-3-658-36430-4_53}, pages = {895 -- 916}, year = {2022}, abstract = {Der Themenkomplex urbane Mobilit{\"a}t ist getrieben durch den Verkehrsinfarkt in Ballungszentren, durch Luftverschmutzung und L{\"a}rm, sowie den Trend zum Leben in der Stadt in den st{\"a}dteplanerischen Fokus ger{\"u}ckt. Emissionsneutrale Antriebskonzepte in der Luftfahrt f{\"u}hren zu Ans{\"a}tzen Flugger{\"a}te einzusetzen, die batteriegetrieben vertikal aufsteigen und landen k{\"o}nnen. Flugphysikalisch und energetisch ist diese Technik nur dann sinnvoll, wenn es zwingende Gr{\"u}nde gibt (z.B. Rettungseins{\"a}tze), daher wird der flugphysikalische Hintergrund prinzipiell erl{\"a}utert. Es werden einige aktuelle Lufttransportkonzepte f{\"u}r eine urbane Personenbef{\"o}rderung vorgestellt. Sollte es verst{\"a}rkt zu Lufttransport {\"u}ber St{\"a}dten kommen, m{\"u}ssen betroffene Luftr{\"a}ume geordnet und {\"u}berwacht werden. Wie kompatibel Lufttransportsysteme mit den heute bereits relevanten urbanen Bef{\"o}rderungsmitteln sein m{\"u}ssen, wird kritisch diskutiert. Abschließend werden die Aspekte Akzeptanz durch die Kunden und Wirtschaftlichkeit ebenso angerissen, wie die hochproblematische Rohstoffgewinnung, die Entsorgung und das Recycling von Batterien.}, language = {de} } @incollection{Fissabre2022, author = {Fissabre, Anke}, title = {Die Bauten des j{\"u}dischen Friedhofs an der L{\"u}tticher Straße}, series = {Der J{\"u}dische Friedhof Aachen}, booktitle = {Der J{\"u}dische Friedhof Aachen}, editor = {Dux, Holger A.}, publisher = {Mayersche Buchhandlung Aachen GmbH}, address = {Aachen}, isbn = {978-3-87519-266-7}, pages = {51 -- 69}, year = {2022}, language = {de} } @incollection{Fissabre2022, author = {Fissabre, Anke}, title = {Ein Entwurf f{\"u}r die Umnutzung der Bauten des j{\"u}dischen Friedhofs an der L{\"u}tticher Straße}, series = {Der j{\"u}dische Friedhof Aachen L{\"u}tticher Straße Aachen}, booktitle = {Der j{\"u}dische Friedhof Aachen L{\"u}tticher Straße Aachen}, editor = {Dux, Holger A.}, publisher = {Mayersche Buchhandlung Aachen GmbH}, address = {Aachen}, isbn = {978-3-87519-266-7}, pages = {71 -- 74}, year = {2022}, language = {de} } @misc{OPUS4-10302, title = {Dimensionen 1-2022: Magazin der FH Aachen University of Applied Sciences - Auf dem Weg zur Nachhaltigkeit}, address = {Aachen}, organization = {Fachhochschule Aachen}, pages = {62 Seiten}, year = {2022}, abstract = {Inhaltsverzeichnis: 06| "WIR" werden nachhaltig 10| Der Kraft-Stoff aus dem Bioreaktor 14| Energieverbrauch des Campus J{\"u}lich optimieren 16| „Eine große Hilfestellung f{\"u}r Flutopfer" 20| Von der ersten Skizze zu den Blumen in der Vase 22|Wie schl{\"a}ft es sich im All, Herr Maurer? 24| Expedition Arktis 28| Eine Frage, zwei Antworten 30| Der sch{\"o}nste Arbeitsplatz der Welt 32| Im Einklang 36| Ein Vorgeschmack auf die echte Arbeitswelt 38| Den R{\"a}tseln des Universums auf der Spur 40| Auf Umwegen in die Spitzenforschung 42| Klappe FH Aachen, die erste … Kamera l{\"a}uft! 44| Auszeit 46| „Fotografie {\"o}ffnet T{\"u}ren zu Parallelwelten" 50| Es gibt viel zu tun 52| Durch-Blick 54| Weichen stellen f{\"u}r einen ganz besonderen Job 58| Souta, Iver und der Wind 60| Die FH Aachen ist systemakkreditiert 61| Der Vulkan 62| Kopfnuss, Impressum}, language = {de} } @masterthesis{Keller2022, type = {Bachelor Thesis}, author = {Keller, Simon Mark}, title = {Risikoanalyse einer bordautonomen Schienenfahrzeugortung mittels GNSS}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {57 Seiten}, year = {2022}, abstract = {Bei Schienenfahrzeugen, die mit dem Zugsicherungssystem ETCS betrieben sind, wird die Odometrie durch eine diskrete Ortung mittels physischen Balisen zur{\"u}ckgesetzt. Diese Arbeit befasst sich mit der Innovation von virtuellen Balisen. Virtuelle Balisen, k{\"o}nnen eingesetzt werden, um physische, im Gleisbett montierte Balisen zu ersetzen. Durch den Einsatz von virtuellen Balisen soll der Infrastrukturausbau von ETCS vorangetrieben werden, indem sie als virtuelle Komponente auf Schienenfahrzeugen eingesetzt werden. Im Rahmen dieser Arbeit wird die Fragestellung beantwortet, ob eine bordautonome Zugortung mittels virtuellen Balisen in einem ausgew{\"a}hlten Szenario mit einem akzeptablen Risiko verbunden ist? Das Szenario besteht aus einem Schienenfahrzeug, welches mit dem Zugsicherungssystem ETCS Level 2 auf einer eingleisigen Nebenstrecke betreiben wird. Hierzu werden zun{\"a}chst die Grundlagen von ETCS und der satellitenbasierten Ortung erl{\"a}utert. Des Weiteren werden die Grundlagen des CSM Prozesses und der expliziten Risikoabsch{\"a}tzung eingef{\"u}hrt. Aufbauend auf diesen Grundlagen wird der CSM Prozess angewandt und dabei eine Systemdefinition mit den Schnittstellen des Systems zur Umwelt erstellt. Mit der Hazop-Methode werden die Gef{\"a}hrdungen der Schnittstellen erfasst und beurteilt. Die sicherheitsrelevanten Gef{\"a}hrdungen werden in einer FMEA bewertet. In der folgenden Diskussion werden sicherheitsrelevante Gef{\"a}hrdungen nochmals betrachtet. Das Ergebnis der Arbeit ist, dass im ausgew{\"a}hlten Szenario, unter der Verwendung der CSM-Prozesse und der industriell anerkannten Methoden Hazop und FMEA, die Integration der Board-autonomen-Ortung mit einem akzeptablen Risiko verbunden ist.}, language = {de} } @incollection{Fissabre2022, author = {Fissabre, Anke}, title = {kirchen-bauhaus? - Die Kunstgewerbeschule in Aachen unter Rudolf Schwarz}, series = {Zwischen den Zeiten - Besatzung und Aufbruch in Aachen, 1919-1932}, booktitle = {Zwischen den Zeiten - Besatzung und Aufbruch in Aachen, 1919-1932}, editor = {Soldwisch, Ines and Schmitz, Stefan}, publisher = {Aachener Karnevalsverein (AKV)}, address = {Aachen}, isbn = {978-3-9825016-0-4}, pages = {54 -- 65}, year = {2022}, language = {de} } @book{Tuennemann2022, author = {T{\"u}nnemann, Thomas}, title = {Formine 2022 : Concezione I}, publisher = {FH Aachen, Fachbereich Architektur}, address = {Aachen}, isbn = {3-9811003-9-5}, publisher = {Fachhochschule Aachen}, pages = {116 Seiten}, year = {2022}, abstract = {Der diesj{\"a}hrige Workshop steht im Zeichen der r{\"a}umlichen Konzeption. Das Definieren und Erfahren des engsten, ganz eigenen Betrachtungsraums, bis hin zur weitl{\"a}ufigen {\"o}ffentlichen Umgebung des Ortes ist hierbei der erste Schritt. Hierzu stehen alle konzeptionellen Werkzeuge - von der Entwicklung vereinzelter Skizzenabfolgen, bis hin zur Collage - in den ersten Tagen des Workshops zur Verf{\"u}gung. Abschließend gilt es, den Aufbau - das „Sichzusammenf{\"u}gen" aus Form, Relation und Material - in einer Plastik zu vereinen.}, language = {de} } @article{HahnHebelManz2022, author = {Hahn, Geogr W. and Hebel, Christoph and Manz, W.}, title = {Die neuen Empfehlungen f{\"u}r Verkehrsnachfragemodellierung im Personenverkehr}, series = {Straßenverkehrstechnik}, volume = {66}, journal = {Straßenverkehrstechnik}, number = {10}, publisher = {Kirschbaum Verlag GmbH}, address = {Bonn}, issn = {0039-2219}, doi = {10.53184/SVT10-2022-1}, pages = {721 -- 726}, year = {2022}, abstract = {Die neu erschienenen „Empfehlungen zum Einsatz von Verkehrsnachfragemodellen f{\"u}r den Personenverkehr" liefern erstmals als Empfehlungspapier der Forschungsgesellschaft f{\"u}r Straßen- und Verkehrswesen einen umfassenden {\"U}berblick zu den verschiedenen Aspekten der Modellierung und geben dem Fachplaner konkrete Hilfestellung f{\"u}r die Konzeption von Nachfragemodellen. Das Empfehlungspapier zielt unter anderem darauf ab, die Erwartungen und das Anspruchsniveau in Hinblick auf Sachgerechtigkeit der Modelle, die erzielbare Modellqualit{\"a}t und den Detaillierungsgrad der Modellaussagen zu harmonisieren.}, language = {de} } @article{EmigHebelSchwark2022, author = {Emig, J. and Hebel, Christoph and Schwark, A.}, title = {Einsatzbereiche f{\"u}r Verkehrsnachfragemodelle}, series = {Straßenverkehrstechnik}, volume = {66}, journal = {Straßenverkehrstechnik}, number = {10}, publisher = {Kirschbaum Verlag GmbH}, address = {Bonn}, issn = {0039-2219}, doi = {10.53184/SVT10-2022-2}, pages = {727 -- 736}, year = {2022}, abstract = {In der Praxis bestehen vielf{\"a}ltige Einsatzbereiche f{\"u}r Verkehrsnachfragemodelle. Mit ihnen k{\"o}nnen Kenngr{\"o}ßen des Verkehrsangebots und der Verkehrsnachfrage f{\"u}r den heutigen Zustand wie auch f{\"u}r zuk{\"u}nftige Zust{\"a}nde bereitgestellt werden, um so die Grundlagen f{\"u}r verkehrsplanerische Entscheidungen zu liefern. Die neuen „Empfehlungen zum Einsatz von Verkehrsnachfragemodellen f{\"u}r den Personenverkehr" (EVNM-PV) (FGSV 2022) veranschaulichen anhand von typischen Planungsaufgaben, welche differenzierten Anforderungen daraus f{\"u}r die Modellkonzeption und -erstellung resultieren. Vor dem Hintergrund der konkreten Aufgabenstellung sowie deren spezifischer planerischer Anforderungen bildet die abzuleitende Modellspezifikation die verabredete Grundlage zwischen Auftraggeber und Modellersteller f{\"u}r die konkrete inhaltliche, fachliche Ausgestaltung des Verkehrsmodells.}, language = {de} } @article{KindmannKrausLaumannetal.2022, author = {Kindmann, Rolf and Kraus, Matthias and Laumann, J{\"o}rg and Vette, Jan}, title = {Verallgemeinerte Berechnungsmethode f{\"u}r in Beton eingespannte Stahlprofile - Einspanntiefen, Tragf{\"a}higkeitsnachweise und Bemessungshilfen}, series = {Stahlbau}, volume = {93}, journal = {Stahlbau}, number = {Early View}, publisher = {Ernst \& Sohn GmbH}, address = {Berlin}, issn = {1437-1049}, doi = {10.1002/stab.202200024}, pages = {1 -- 25}, year = {2022}, abstract = {St{\"u}tzen und Tr{\"a}ger aus Stahlprofilen k{\"o}nnen in Fundamente oder W{\"a}nde aus Stahlbeton einbetoniert werden. Diese Anschl{\"u}sse wirken in der Regel wie Einspannungen, die eine ausreichende Einspanntiefe erfordern. Im Folgenden wird eine verallgemeinerte Berechnungsmethode f{\"u}r in Stahlbetonkonstruktionen eingespannte Stahlprofile aus gewalzten I-Profilen, geschweißten I-Profilen, runden Hohlprofilen, eckigen Hohlprofilen und einzelligen Kastenquerschnitten vorgestellt. F{\"u}r Beanspruchungen infolge einachsiger Biegung um die starke und schwache Profilachse werden der profilabh{\"a}ngige Ansatz der Betondruckspannungen im Einspannbereich und die Ermittlung der Einspanntiefe behandelt. Unter Ber{\"u}cksichtigung der Normalkraft werden an den maßgebenden Stellen Tragf{\"a}higkeitsnachweise f{\"u}r die Stahlprofile gef{\"u}hrt. Als Erg{\"a}nzung zu den Berechnungsformeln werden Bemessungshilfen zur Verf{\"u}gung gestellt, die die Wahl der mitwirkenden Breiten und der Einspanntiefen erleichtert.}, language = {de} } @book{LaumannFeldmannFrickeletal.2022, author = {Laumann, J{\"o}rg and Feldmann, Markus and Frickel, J{\"o}rg and Krahwinkel, Manuel and Kraus, Matthias and Strangh{\"o}ner, Natalie and Ummenhofer, Thomas}, title = {Petersen Stahlbau : Grundlagen der Berechnung und baulichen Ausbildung von Stahlbauten}, edition = {5. Auflage}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-20510-2}, doi = {10.1007/978-3-658-20510-2}, pages = {XXIII, 1919 Seiten}, year = {2022}, abstract = {Die Theorie und Konstruktion der wichtigsten Bereiche der Stahlbautechnik werden von den Grundlagen her entwickelt und durch viele Beispiele praxisbezogen erl{\"a}utert. Das Buch ist aus Vorlesungen im Grund- und Vertiefungsstudium des Bauingenieurwesens entstanden. Der Inhalt wird zum Teil systematisch, zum Teil exemplarisch dargestellt. F{\"u}r Konstrukteure und Statiker in den technischen B{\"u}ros, der Beratenden Ingenieure und der Pr{\"u}f{\"a}mter enth{\"a}lt das Buch aufbereitete Berechnungsverfahren und Konstruktionsvorschl{\"a}ge in großer Zahl.}, language = {de} } @incollection{BensbergCzarneckiGrob2022, author = {Bensberg, Frank and Czarnecki, Christian and Grob, Heinz Lothar}, title = {Wirtschaftlichkeitsbewertung von Smart Services mit vollst{\"a}ndigen Finanzpl{\"a}nen}, series = {Smart Services: Band 1: Konzepte - Methoden - Prozesse}, booktitle = {Smart Services: Band 1: Konzepte - Methoden - Prozesse}, editor = {Bruhn, Manfred and Hadwich, Karsten}, publisher = {Springer Gabler}, address = {Wiesbaden}, isbn = {978-3-658-37344-3 (Online)}, doi = {10.1007/978-3-658-37344-3_6}, pages = {225 -- 251}, year = {2022}, abstract = {Dieser Beitrag stellt einen Bewertungsrahmen f{\"u}r Smart Services vor, der auf dem Konzept vollst{\"a}ndiger Finanzpl{\"a}ne (VOFI) basiert. Zun{\"a}chst wird eine IoT-Architektur f{\"u}r Smart Services eingef{\"u}hrt, die die Grundlage f{\"u}r deren Betrachtung aus Sicht der Unternehmensplanung liefert. Hierauf aufbauend wird ein Bewertungsrahmen f{\"u}r die finanzplanorientierte Wirtschaftlichkeitsbewertung von Smart Services geschaffen, mit dem die relevanten Zahlungsfolgen differenziert erfasst werden. Mithilfe des entwickelten VOFI-Systems wird anschließend aufgezeigt, wie mithilfe einer Risikoanalyse die Unsicherheit von Modellparametern ber{\"u}cksichtigt werden kann.}, language = {de} } @article{BaringhausGaigall2022, author = {Baringhaus, Ludwig and Gaigall, Daniel}, title = {A goodness-of-fit test for the compound Poisson exponential model}, series = {Journal of Multivariate Analysis}, volume = {195}, journal = {Journal of Multivariate Analysis}, number = {Article 105154}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0047-259X}, doi = {10.1016/j.jmva.2022.105154}, year = {2022}, abstract = {On the basis of bivariate data, assumed to be observations of independent copies of a random vector (S,N), we consider testing the hypothesis that the distribution of (S,N) belongs to the parametric class of distributions that arise with the compound Poisson exponential model. Typically, this model is used in stochastic hydrology, with N as the number of raindays, and S as total rainfall amount during a certain time period, or in actuarial science, with N as the number of losses, and S as total loss expenditure during a certain time period. The compound Poisson exponential model is characterized in the way that a specific transform associated with the distribution of (S,N) satisfies a certain differential equation. Mimicking the function part of this equation by substituting the empirical counterparts of the transform we obtain an expression the weighted integral of the square of which is used as test statistic. We deal with two variants of the latter, one of which being invariant under scale transformations of the S-part by fixed positive constants. Critical values are obtained by using a parametric bootstrap procedure. The asymptotic behavior of the tests is discussed. A simulation study demonstrates the performance of the tests in the finite sample case. The procedure is applied to rainfall data and to an actuarial dataset. A multivariate extension is also discussed.}, language = {en} } @inproceedings{EvansBraunUlmeretal.2022, author = {Evans, Benjamin and Braun, Sebastian and Ulmer, Jessica and Wollert, J{\"o}rg}, title = {AAS implementations - current problems and solutions}, series = {20th International Conference on Mechatronics - Mechatronika (ME)}, booktitle = {20th International Conference on Mechatronics - Mechatronika (ME)}, publisher = {IEEE}, address = {New York, NY}, isbn = {978-1-6654-1040-3}, doi = {10.1109/ME54704.2022.9982933}, pages = {6 Seiten}, year = {2022}, abstract = {The fourth industrial revolution presents a multitude of challenges for industries, one of which being the increased flexibility required of manufacturing lines as a result of increased consumer demand for individualised products. One solution to tackle this challenge is the digital twin, more specifically the standardised model of a digital twin also known as the asset administration shell. The standardisation of an industry wide communications tool is a critical step in enabling inter-company operations. This paper discusses the current state of asset administration shells, the frameworks used to host them and their problems that need to be addressed. To tackle these issues, we propose an event-based server capable of drastically reducing response times between assets and asset administration shells and a multi-agent system used for the orchestration and deployment of the shells in the field.}, language = {en} } @inproceedings{WiegnerVolkerMainzetal.2022, author = {Wiegner, Jonas and Volker, Hanno and Mainz, Fabian and Backes, Andreas and L{\"o}ken, Michael and H{\"u}ning, Felix}, title = {Wiegand-effect-powered wireless IoT sensor node}, series = {ITG-Fb. 303: Sensoren und Messsysteme}, booktitle = {ITG-Fb. 303: Sensoren und Messsysteme}, publisher = {VDE Verlag GmbH}, address = {Berlin}, isbn = {978-3-8007-5835-7}, pages = {255 -- 260}, year = {2022}, abstract = {In this article we describe an Internet-of-Things sensing device with a wireless interface which is powered by the oftenoverlooked harvesting method of the Wiegand effect. The sensor can determine position, temperature or other resistively measurable quantities and can transmit the data via an ultra-low power ultra-wideband (UWB) data transmitter. With this approach we can energy-self-sufficiently acquire, process, and wirelessly transmit data in a pulsed operation. A proof-of-concept system was built up to prove the feasibility of the approach. The energy consumption of the system is analyzed and traced back in detail to the individual components, compared to the generated energy and processed to identify further optimization options. Based on the proof-of-concept, an application demonstrator was developed. Finally, we point out possible use cases.}, language = {en} } @article{UlmerBraunChengetal.2022, author = {Ulmer, Jessica and Braun, Sebastian and Cheng, Chi-Tsun and Dowey, Steve and Wollert, J{\"o}rg}, title = {Gamification of virtual reality assembly training: Effects of a combined point and level system on motivation and training results}, series = {International Journal of Human-Computer Studies}, volume = {165}, journal = {International Journal of Human-Computer Studies}, number = {Art. No. 102854}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1071-5819}, doi = {10.1016/j.ijhcs.2022.102854}, year = {2022}, abstract = {Virtual Reality (VR) offers novel possibilities for remote training regardless of the availability of the actual equipment, the presence of specialists, and the training locations. Research shows that training environments that adapt to users' preferences and performance can promote more effective learning. However, the observed results can hardly be traced back to specific adaptive measures but the whole new training approach. This study analyzes the effects of a combined point and leveling VR-based gamification system on assembly training targeting specific training outcomes and users' motivations. The Gamified-VR-Group with 26 subjects received the gamified training, and the Non-Gamified-VR-Group with 27 subjects received the alternative without gamified elements. Both groups conducted their VR training at least three times before assembling the actual structure. The study found that a level system that gradually increases the difficulty and error probability in VR can significantly lower real-world error rates, self-corrections, and support usages. According to our study, a high error occurrence at the highest training level reduced the Gamified-VR-Group's feeling of competence compared to the Non-Gamified-VR-Group, but at the same time also led to lower error probabilities in real-life. It is concluded that a level system with a variable task difficulty should be combined with carefully balanced positive and negative feedback messages. This way, better learning results, and an improved self-evaluation can be achieved while not causing significant impacts on the participants' feeling of competence.}, language = {en} } @masterthesis{Schnitzler2022, type = {Bachelor Thesis}, author = {Schnitzler, Nora}, title = {Identifikation und Bewertung geeigneter Mikrostrukturierungen zum Schutz von Biohybridbeschichtungen von Zahnimplantaten vor Abrasion beim Z{\"a}hneputzen}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {67 S.}, year = {2022}, abstract = {Die Oberfl{\"a}chen dentaler Implantate sind definiert durch eine raue Oberfl{\"a}che, um die Integration in den menschlichen Knochen zu optimieren. Entz{\"u}ndungen des umgebenden Zahnfleisches z{\"a}hlen dabei zu den h{\"a}ufigsten Komplikationen nach einer Implantation. Diese Entz{\"u}ndungen entstehen haupts{\"a}chlich durch bakterielle Infektionen des Weichgewebes an der Implantations-Stelle. Die raue Oberfl{\"a}che tr{\"a}gt jedoch zu einer solchen Infektion bei. Da der Implantat-Kopf zum Teil aus dem Knochen herausragt, erfolgt beispielsweise beim Z{\"a}hneputzen eine Freilegung der Implantat-Oberfl{\"a}che. Die durch die Rauheit vergr{\"o}ßerte Oberfl{\"a}che bietet dabei ideale Voraussetzungen f{\"u}r eine Bakterienansiedlung. In der aktuellen Forschung steht die Entwicklung einer Oberfl{\"a}che im Vordergrund, die eine antibakterielle Funktionalisierung erzeugt. Diese verhindert die Bakterienansiedlung und wirkt einer Entz{\"u}ndung entgegen. Um die Beschichtung vor Verschleiß zu sch{\"u}tzen und ihre Lebensdauer der antibakteriellen Wirkung zu erh{\"o}hen, ist es m{\"o}glich die Oberfl{\"a}che mit einer Mikrostruktur zu versehen. Das Ziel der vorliegenden Arbeit ist die Identifikation geeigneter Mikrostrukturierungen, die der antibakteriellen Beschichtung einen optimalen Schutz vor Verschleiß bieten. Am Beispiel von Titan-Zahnimplantaten wird der Schutz der aufgetragenen Biohybridbeschichtung gegen abrasiven Verschleiß untersucht. Im Vorfeld wird eine Analyse der fertigungstechnischen M{\"o}glichkeiten mit Blick auf dentale Implantate und Mikrostrukturen durchgef{\"u}hrt, um das ein passendes Verfahren zu identifizieren. Die Analogiebauteile als Probenk{\"o}rper werden, mithilfe des zuvor ausgew{\"a}hlten Verfahrens, mit verschiedenen Mikrostrukturen versehen. Im Rahmen einer Versuchsdurchf{\"u}hrung, die die mechanische Belastung bei einem Zahnputzdurchgang imitiert, werden die verschiedenen Mikrostrukturen auf ihre Eignung f{\"u}r diese Anwendung {\"u}berpr{\"u}ft. Ein Vorversuch dient zur Identifizierung eines geeigneten Ankerpeptids, welches den bindenden Bestandteil der Biohybridbeschichtung darstellt. Aus drei zuvor ausgew{\"a}hlten Ankerpeptiden wird das mit der besten Adh{\"a}sionsf{\"a}higkeit herausgestellt. Im finalen Versuchsdurchlauf wird das Ankerpeptid auf die Oberfl{\"a}chen, die mit den Mikrostrukturen versehen sind, aufgetragen. Dabei ist das Ziel eine Mikrostruktur herauszustellen, die den h{\"o}chstm{\"o}glichen Schutz bietet. Durch eine Fluoreszenzpr{\"u}fung mithilfe eines Flourescence Plate Readers wird jede Kombination nach den Belastungsversuchen auf den Restanteil der Beschichtung {\"u}berpr{\"u}ft. Das Ergebnis stellt eine Mikrostruktur dar, die den bestm{\"o}glichen Schutz bietet. Dies ist erkennbar durch den h{\"o}chsten Anteil an Restbeschichtung. Eine Strukturierung mit sogenannten Micro-Grooves in Kombination mit dem MacHis-Ankerpeptid erzielte in der Analyse der Belastungssimulationen die besten Ergebnisse bez{\"u}glich des Schutzes der Beschichtung. Durch die Versuche best{\"a}tigte sich eine weitere Annahme. Die Strukturierung der Oberfl{\"a}che erzielt einen deutlich h{\"o}heren Schutz im Vergleich zu einer unstrukturierten Oberfl{\"a}che. Zudem hat sich herausgestellt, dass eine Beschichtung mit dem sogenannten PEO-Verfahren eine deutlich gr{\"o}ßere Adh{\"a}sion der Biohybridbeschichtung erzielt. Dies wird jedoch Thema weiterf{\"u}hrender Forschungen sein und kein Bestandteil der vorliegenden Arbeit.}, language = {de} } @article{PfaffEnningSutter2022, author = {Pfaff, Raphael and Enning, Manfred and Sutter, Stefan}, title = {A risk‑based approach to automatic brake tests for rail freight service: incident analysis and realisation concept}, series = {SN Applied Sciences}, volume = {4}, journal = {SN Applied Sciences}, number = {4}, publisher = {Springer}, address = {Cham}, issn = {2523-3971}, doi = {10.1007/s42452-022-05007-x}, pages = {1 -- 14}, year = {2022}, abstract = {This study reviews the practice of brake tests in freight railways, which is time consuming and not suitable to detect certain failure types. Public incident reports are analysed to derive a reasonable brake test hardware and communication architecture, which aims to provide automatic brake tests at lower cost than current solutions. The proposed solutions relies exclusively on brake pipe and brake cylinder pressure sensors, a brake release position switch as well as radio communication via standard protocols. The approach is embedded in the Wagon 4.0 concept, which is a holistic approach to a smart freight wagon. The reduction of manual processes yields a strong incentive due to high savings in manual labour and increased productivity.}, language = {en} } @incollection{SchubaHoefken2022, author = {Schuba, Marko and H{\"o}fken, Hans-Wilhelm}, title = {Cybersicherheit in Produktion, Automotive und intelligenten Geb{\"a}uden}, series = {IT-Sicherheit - Technologien und Best Practices f{\"u}r die Umsetzung im Unternehmen}, booktitle = {IT-Sicherheit - Technologien und Best Practices f{\"u}r die Umsetzung im Unternehmen}, publisher = {Carl Hanser Verlag}, address = {M{\"u}nchen}, isbn = {978-3-446-47223-5}, doi = {10.3139/9783446473478.012}, pages = {193 -- 218}, year = {2022}, language = {de} } @incollection{EnglaenderKaminskiSchuba2022, author = {Engl{\"a}nder, Jacques and Kaminski, Lars and Schuba, Marko}, title = {Informationssicherheitsmanagement}, series = {Digitalisierungs- und Informationsmanagement}, booktitle = {Digitalisierungs- und Informationsmanagement}, publisher = {Springer Vieweg}, address = {Berlin}, isbn = {978-3-662-63757-9}, doi = {10.1007/978-3-662-63758-6_15}, pages = {373 -- 398}, year = {2022}, abstract = {Daten und Informationen sind die wichtigsten Ressourcen vieler Unternehmen und m{\"u}ssen daher entsprechend gesch{\"u}tzt werden. Getrieben durch die erh{\"o}hte Vernetzung von Informationstechnologie, die h{\"o}here Offenheit infolge datengetriebener Dienstleistungen und eine starke Zunahme an Datenquellen, r{\"u}cken die Gefahren von Informationsdiebstahl, -manipulation und -verlust in den Fokus von produzierenden Unternehmen. Auf dem Weg zum lern- und wandlungsf{\"a}higen Unternehmen kann dies zu einem großen Hindernis werden, da einerseits zu hohe Sicherheitsanforderungen neue Entwicklungen beschr{\"a}nken, andererseits wegen des Mangels an ausreichenden Informationssicherheitskonzepten Unternehmen weniger Innovationen wagen. Deshalb bedarf es individuell angepasster Konzepte f{\"u}r die Bereiche IT-Security, IT-Safety und Datenschutz f{\"u}r vernetzte Produkte, Produktion und Arbeitspl{\"a}tze. Bei der Entwicklung und Durchsetzung dieser Konzepte steht der Faktor Mensch im Zentrum aller {\"U}berlegungen. In diesem Kapitel wird dargestellt, wie der Faktor Mensch bei der Erstellung von Informationssicherheitskonzepten in verschiedenen Phasen zu beachten ist. Beginnend mit der Integration von Informationssystemen und damit verbundenen Sicherheitsmaßnahmen, {\"u}ber die Administration, bis hin zur Anwendung durch den Endnutzer, werden Methoden beschrieben, die den Menschen, verbunden mit seinem Mehrwert wie auch den Risiken, einschließen. Dabei werden sowohl Grundlagen aufgezeigt als auch Konzepte vorgestellt, mit denen Entscheider in der Unternehmens-IT Leitlinien f{\"u}r die Informationssicherheit festlegen k{\"o}nnen.}, language = {de} } @inproceedings{SchubaHoefkenLinzbach2022, author = {Schuba, Marko and H{\"o}fken, Hans-Wilhelm and Linzbach, Sophie}, title = {An ICS Honeynet for Detecting and Analyzing Cyberattacks in Industrial Plants}, series = {2021 International Conference on Electrical, Computer and Energy Technologies (ICECET)}, booktitle = {2021 International Conference on Electrical, Computer and Energy Technologies (ICECET)}, publisher = {IEEE}, isbn = {978-1-6654-4231-2}, doi = {10.1109/ICECET52533.2021.9698746}, pages = {6 Seiten}, year = {2022}, abstract = {Cybersecurity of Industrial Control Systems (ICS) is an important issue, as ICS incidents may have a direct impact on safety of people or the environment. At the same time the awareness and knowledge about cybersecurity, particularly in the context of ICS, is alarmingly low. Industrial honeypots offer a cheap and easy to implement way to raise cybersecurity awareness and to educate ICS staff about typical attack patterns. When integrated in a productive network, industrial honeypots may not only reveal attackers early but may also distract them from the actual important systems of the network. Implementing multiple honeypots as a honeynet, the systems can be used to emulate or simulate a whole Industrial Control System. This paper describes a network of honeypots emulating HTTP, SNMP, S7communication and the Modbus protocol using Conpot, IMUNES and SNAP7. The nodes mimic SIMATIC S7 programmable logic controllers (PLCs) which are widely used across the globe. The deployed honeypots' features will be compared with the features of real SIMATIC S7 PLCs. Furthermore, the honeynet has been made publicly available for ten days and occurring cyberattacks have been analyzed}, language = {en} } @book{Lauth2022, author = {Lauth, Jakob}, title = {Physikalische Chemie kompakt}, publisher = {Springer Spektrum}, address = {Berlin}, isbn = {978-3-662-64587-1}, doi = {https://doi.org/10.1007/978-3-662-64588-8}, pages = {XXIV, 263 Seiten}, year = {2022}, language = {de} } @article{MalinowskiFournierHorbachetal.2022, author = {Malinowski, Daniel and Fournier, Yvan and Horbach, Andreas and Frick, Michael and Magliani, Mirko and Kalverkamp, Sebastian and Hildinger, Martin and Spillner, Jan and Behbahani, Mehdi and Hima, Flutura}, title = {Computational fluid dynamics analysis of endoluminal aortic perfusion}, series = {Perfusion}, volume = {0}, journal = {Perfusion}, number = {0}, publisher = {Sage}, address = {London}, issn = {1477-111X}, doi = {10.1177/02676591221099809}, pages = {1 -- 8}, year = {2022}, abstract = {Introduction: In peripheral percutaneous (VA) extracorporeal membrane oxygenation (ECMO) procedures the femoral arteries perfusion route has inherent disadvantages regarding poor upper body perfusion due to watershed. With the advent of new long flexible cannulas an advancement of the tip up to the ascending aorta has become feasible. To investigate the impact of such long endoluminal cannulas on upper body perfusion, a Computational Fluid Dynamics (CFD) study was performed considering different support levels and three cannula positions. Methods: An idealized literature-based- and a real patient proximal aortic geometry including an endoluminal cannula were constructed. The blood flow was considered continuous. Oxygen saturation was set to 80\% for the blood coming from the heart and to 100\% for the blood leaving the cannula. 50\% and 90\% venoarterial support levels from the total blood flow rate of 6 l/min were investigated for three different positions of the cannula in the aortic arch. Results: For both geometries, the placement of the cannula in the ascending aorta led to a superior oxygenation of all aortic blood vessels except for the left coronary artery. Cannula placements at the aortic arch and descending aorta could support supra-aortic arteries, but not the coronary arteries. All positions were able to support all branches with saturated blood at 90\% flow volume. Conclusions: In accordance with clinical observations CFD analysis reveals, that retrograde advancement of a long endoluminal cannula can considerably improve the oxygenation of the upper body and lead to oxygen saturation distributions similar to those of a central cannulation.}, language = {en} } @article{LenzKahmannBehbahanietal.2022, author = {Lenz, Maximilian and Kahmann, Stephanie Lucina and Behbahani, Mehdi and Pennig, Lenhard and Hackl, Michael and Leschinger, Tim and M{\"u}ller, Lars Peter and Wegmann, Kilian}, title = {Influence of rotator cuff preload on fracture configuration in proximal humerus fractures: a proof of concept for fracture simulation}, series = {Archives of Orthopaedic and Trauma Surgery}, journal = {Archives of Orthopaedic and Trauma Surgery}, publisher = {Springer}, address = {Berlin, Heidelberg}, issn = {1434-3916}, doi = {10.1007/s00402-022-04471-9}, year = {2022}, abstract = {Introduction In regard of surgical training, the reproducible simulation of life-like proximal humerus fractures in human cadaveric specimens is desirable. The aim of the present study was to develop a technique that allows simulation of realistic proximal humerus fractures and to analyse the influence of rotator cuff preload on the generated lesions in regards of fracture configuration. Materials and methods Ten cadaveric specimens (6 left, 4 right) were fractured using a custom-made drop-test bench, in two groups. Five specimens were fractured without rotator cuff preload, while the other five were fractured with the tendons of the rotator cuff preloaded with 2 kg each. The humeral shaft and the shortened scapula were potted. The humerus was positioned at 90° of abduction and 10° of internal rotation to simulate a fall on the elevated arm. In two specimens of each group, the emergence of the fractures was documented with high-speed video imaging. Pre-fracture radiographs were taken to evaluate the deltoid-tuberosity index as a measure of bone density. Post-fracture X-rays and CT scans were performed to define the exact fracture configurations. Neer's classification was used to analyse the fractures. Results In all ten cadaveric specimens life-like proximal humerus fractures were achieved. Two III-part and three IV-part fractures resulted in each group. The preloading of the rotator cuff muscles had no further influence on the fracture configuration. High-speed videos of the fracture simulation revealed identical fracture mechanisms for both groups. We observed a two-step fracture mechanism, with initial impaction of the head segment against the glenoid followed by fracturing of the head and the tuberosities and then with further impaction of the shaft against the acromion, which lead to separation of the tuberosities. Conclusion A high energetic axial impulse can reliably induce realistic proximal humerus fractures in cadaveric specimens. The preload of the rotator cuff muscles had no influence on initial fracture configuration. Therefore, fracture simulation in the proximal humerus is less elaborate. Using the presented technique, pre-fractured specimens are available for real-life surgical education.}, language = {en} } @article{ChloeMalyaranCraveiroetal.2022, author = {Chlo{\´e}, Radermacher and Malyaran, Hanna and Craveiro, Rogerio Bastos and Peglow, Sarah and Behbahani, Mehdi and Pufe, Thomas and Wolf, Michael and Neuss, Sabine}, title = {Mechanical loading on cementoblasts: a mini review}, series = {Osteologie}, volume = {31}, journal = {Osteologie}, number = {2}, publisher = {Thieme}, address = {Stuttgart}, issn = {1019-1291}, doi = {10.1055/a-1826-0777}, pages = {111 -- 118}, year = {2022}, abstract = {Orthodontic treatments are concomitant with mechanical forces and thereby cause teeth movements. The applied forces are transmitted to the tooth root and the periodontal ligaments which is compressed on one side and tensed up on the other side. Indeed, strong forces can lead to tooth root resorption and the crown-to-tooth ratio is reduced with the potential for significant clinical impact. The cementum, which covers the tooth root, is a thin mineralized tissue of the periodontium that connects the periodontal ligament with the tooth and is build up by cementoblasts. The impact of tension and compression on these cells is investigated in several in vivo and in vitro studies demonstrating differences in protein expression and signaling pathways. In summary, osteogenic marker changes indicate that cyclic tensile forces support whereas static tension inhibits cementogenesis. Furthermore, cementogenesis experiences the same protein expression changes in static conditions as static tension, but cyclic compression leads to the exact opposite of cyclic tension. Consistent with marker expression changes, the singaling pathways of Wnt/ß-catenin and RANKL/OPG show that tissue compression leads to cementum degradation and tension forces to cementogenesis. However, the cementum, and in particular its cementoblasts, remain a research area which should be explored in more detail to understand the underlying mechanism of bone resorption and remodeling after orthodontic treatments.}, language = {en} } @inproceedings{ChavezBermudezWollert2022, author = {Chavez Bermudez, Victor Francisco and Wollert, J{\"o}rg}, title = {10BASE-T1L industry 4.0 smart switch for field devices based on IO-Link}, series = {2022 IEEE 18th International Conference on Factory Communication Systems (WFCS)}, booktitle = {2022 IEEE 18th International Conference on Factory Communication Systems (WFCS)}, publisher = {IEEE}, address = {New York, NY}, isbn = {978-1-6654-1086-1}, doi = {10.1109/WFCS53837.2022.9779176}, pages = {4 Seiten}, year = {2022}, abstract = {The recent amendment to the Ethernet physical layer known as the IEEE 802.3cg specification, allows to connect devices up to a distance of one kilometer and delivers a maximum of 60 watts of power over a twisted pair of wires. This new standard, also known as 10BASE-TIL, promises to overcome the limits of current physical layers used for field devices and bring them a step closer to Ethernet-based applications. The main advantage of 10BASE- TIL is that it can deliver power and data over the same line over a long distance, where traditional solutions (e.g., CAN, IO-Link, HART) fall short and cannot match its 10 Mbps bandwidth. Due to its recentness, IOBASE- TIL is still not integrated into field devices and it has been less than two years since silicon manufacturers released the first Ethernet-PHY chips. In this paper, we present a design proposal on how field devices could be integrated into a IOBASE-TIL smart switch that allows plug-and-play connectivity for sensors and actuators and is compliant with the Industry 4.0 vision. Instead of presenting a new field-level protocol for this work, we have decided to adopt the IO-Link specification which already includes a plug-and-play approach with features such as diagnosis and device configuration. The main objective of this work is to explore how field devices could be integrated into 10BASE-TIL Ethernet, its adaption with a well-known protocol, and its integration with Industry 4.0 technologies.}, language = {en} } @inproceedings{UlmerBraunChengetal.2022, author = {Ulmer, Jessica and Braun, Sebastian and Cheng, Chi-Tsun and Dowey, Steve and Wollert, J{\"o}rg}, title = {Usage of digital twins for gamification applications in manufacturing}, series = {Procedia CIRP Leading manufacturing systems transformation - Proceedings of the 55th CIRP Conference on Manufacturing Systems 2022}, volume = {107}, booktitle = {Procedia CIRP Leading manufacturing systems transformation - Proceedings of the 55th CIRP Conference on Manufacturing Systems 2022}, publisher = {Elsevier}, address = {Amsterdam}, issn = {2212-8271}, doi = {10.1016/j.procir.2022.05.044}, pages = {675 -- 680}, year = {2022}, abstract = {Gamification applications are on the rise in the manufacturing sector to customize working scenarios, offer user-specific feedback, and provide personalized learning offerings. Commonly, different sensors are integrated into work environments to track workers' actions. Game elements are selected according to the work task and users' preferences. However, implementing gamified workplaces remains challenging as different data sources must be established, evaluated, and connected. Developers often require information from several areas of the companies to offer meaningful gamification strategies for their employees. Moreover, work environments and the associated support systems are usually not flexible enough to adapt to personal needs. Digital twins are one primary possibility to create a uniform data approach that can provide semantic information to gamification applications. Frequently, several digital twins have to interact with each other to provide information about the workplace, the manufacturing process, and the knowledge of the employees. This research aims to create an overview of existing digital twin approaches for digital support systems and presents a concept to use digital twins for gamified support and training systems. The concept is based upon the Reference Architecture Industry 4.0 (RAMI 4.0) and includes information about the whole life cycle of the assets. It is applied to an existing gamified training system and evaluated in the Industry 4.0 model factory by an example of a handle mounting.}, language = {en} } @inproceedings{DannenSchindelePruemmeretal.2022, author = {Dannen, Tammo and Schindele, Benedikt and Pr{\"u}mmer, Marcel and Arntz, Kristian and Bergs, Thomas}, title = {Methodology for the self-optimizing determination of additive manufacturing process eligibility and optimization potentials in toolmaking}, series = {Procedia CIRP Leading manufacturing systems transformation - Proceedings of the 55th CIRP Conference on Manufacturing Systems 2022}, volume = {107}, booktitle = {Procedia CIRP Leading manufacturing systems transformation - Proceedings of the 55th CIRP Conference on Manufacturing Systems 2022}, publisher = {Elsevier}, address = {Amsterdam}, issn = {2212-8271}, doi = {10.1016/j.procir.2022.05.188}, pages = {1539 -- 1544}, year = {2022}, abstract = {Additive Manufacturing (AM) of metallic workpieces faces a continuously rising technological relevance and market size. Producing complex or highly strained unique workpieces is a significant field of application, making AM highly relevant for tool components. Its successful economic application requires systematic workpiece based decisions and optimizations. Considering geometric and technological requirements as well as the necessary post-processing makes deciding effortful and requires in-depth knowledge. As design is usually adjusted to established manufacturing, associated technological and strategic potentials are often neglected. To embed AM in a future proof industrial environment, software-based self-learning tools are necessary. Integrated into production planning, they enable companies to unlock the potentials of AM efficiently. This paper presents an appropriate methodology for the analysis of process-specific AM-eligibility and optimization potential, added up by concrete optimization proposals. For an integrated workpiece characterization, proven methods are enlarged by tooling-specific figures. The first stage of the approach specifies the model's initialization. A learning set of tooling components is described using the developed key figure system. Based on this, a set of applicable rules for workpiece-specific result determination is generated through clustering and expert evaluation. Within the following application stage, strategic orientation is quantified and workpieces of interest are described using the developed key figures. Subsequently, the retrieved information is used for automatically generating specific recommendations relying on the generated ruleset of stage one. Finally, actual experiences regarding the recommendations are gathered within stage three. Statistic learning transfers those to the generated ruleset leading to a continuously deepening knowledge base. This process enables a steady improvement in output quality.}, language = {en} } @incollection{Timme2022, author = {Timme, Michael}, title = {Wettbewerbsregeln (\S\S 24-27)}, series = {M{\"u}nchener Kommentar zum europ{\"a}ischen und deutschen Wettbewerbsrecht : Kartellrecht, Beihilfenrecht, Vergaberecht / hrsg von Franz J{\"u}rgen S{\"a}cker / Band 2: Deutsches Wettbewerbsrecht Gesetz gegen Wettbewerbsbeschr{\"a}nkungen (GWB), \S\S 1-96, 185, 186}, booktitle = {M{\"u}nchener Kommentar zum europ{\"a}ischen und deutschen Wettbewerbsrecht : Kartellrecht, Beihilfenrecht, Vergaberecht / hrsg von Franz J{\"u}rgen S{\"a}cker / Band 2: Deutsches Wettbewerbsrecht Gesetz gegen Wettbewerbsbeschr{\"a}nkungen (GWB), \S\S 1-96, 185, 186}, publisher = {Beck}, address = {M{\"u}nchen}, isbn = {978-3-406-75876-8}, pages = {589 -- 608}, year = {2022}, language = {de} } @article{EmhardtJarodzkaBrandGruweletal.2022, author = {Emhardt, Selina N. and Jarodzka, Halszka and Brand-Gruwel, Saskia and Drumm, Christian and Niehorster, Diederick C. and van Gog, Tamara}, title = {What is my teacher talking about? Effects of displaying the teacher's gaze and mouse cursor cues in video lectures on students' learning}, series = {Journal of Cognitive Psychology}, journal = {Journal of Cognitive Psychology}, publisher = {Routledge, Taylor \& Francis Group}, address = {Abingdon}, issn = {2044-5911}, doi = {10.1080/20445911.2022.2080831}, pages = {1 -- 19}, year = {2022}, abstract = {Eye movement modelling examples (EMME) are instructional videos that display a teacher's eye movements as "gaze cursor" (e.g. a moving dot) superimposed on the learning task. This study investigated if previous findings on the beneficial effects of EMME would extend to online lecture videos and compared the effects of displaying the teacher's gaze cursor with displaying the more traditional mouse cursor as a tool to guide learners' attention. Novices (N = 124) studied a pre-recorded video lecture on how to model business processes in a 2 (mouse cursor absent/present) × 2 (gaze cursor absent/present) between-subjects design. Unexpectedly, we did not find significant effects of the presence of gaze or mouse cursors on mental effort and learning. However, participants who watched videos with the gaze cursor found it easier to follow the teacher. Overall, participants responded positively to the gaze cursor, especially when the mouse cursor was not displayed in the video.}, language = {en} } @article{FiedlerOrzadaFloeseretal.2022, author = {Fiedler, Thomas M. and Orzada, Stephan and Fl{\"o}ser, Martina and Rietsch, Stefan H. G. and Schmidt, Simon and Stelter, Jonathan K. and Wittrich, Marco and Quick, Harald H. and Bitz, Andreas and Ladd, Mark E.}, title = {Performance and safety assessment of an integrated transmit array for body imaging at 7 T under consideration of specificabsorption rate, tissue temperature, and thermal dose}, series = {NMR in Biomedicine}, volume = {35}, journal = {NMR in Biomedicine}, number = {5}, publisher = {Wiley}, issn = {0952-3480 (Print)}, doi = {10.1002/nbm.4656}, pages = {1 -- 17}, year = {2022}, abstract = {In this study, the performance of an integrated body-imaging array for 7 T with 32 radiofrequency (RF) channels under consideration of local specific absorption rate (SAR), tissue temperature, and thermal dose limits was evaluated and the imaging performance was compared with a clinical 3 T body coil. Thirty-two transmit elements were placed in three rings between the bore liner and RF shield of the gradient coil. Slice-selective RF pulse optimizations for B1 shimming and spokes were performed for differently oriented slices in the body under consideration of realistic constraints for power and local SAR. To improve the B1+ homogeneity, safety assessments based on temperature and thermal dose were performed to possibly allow for higher input power for the pulse optimization than permissible with SAR limits. The results showed that using two spokes, the 7 T array outperformed the 3 T birdcage in all the considered regions of interest. However, a significantly higher SAR or lower duty cycle at 7 T is necessary in some cases to achieve similar B1+ homogeneity as at 3 T. The homogeneity in up to 50 cm-long coronal slices can particularly benefit from the high RF shim performance provided by the 32 RF channels. The thermal dose approach increases the allowable input power and the corresponding local SAR, in one example up to 100 W/kg, without limiting the exposure time necessary for an MR examination. In conclusion, the integrated antenna array at 7 T enables a clinical workflow for body imaging and comparable imaging performance to a conventional 3 T clinical body coil.}, language = {en} } @techreport{KlugeKirschBudach2022, author = {Kluge, Katharina and Kirsch, Ansgar and Budach, Christoph}, title = {Digitale Lehre in der Geotechnik: Aktueller Stand und weitere Entwicklungen}, series = {geotechntik}, journal = {geotechntik}, number = {Early View}, publisher = {Ernst \& Sohn}, address = {Berlin}, issn = {0172-6145 (Print)}, doi = {10.1002/gete.202200013}, pages = {8 Seiten}, year = {2022}, abstract = {Digitale Lehrmaterialien werden seit mehreren Jahren in den Hochschulen eingesetzt und er{\"o}ffnen ganz neue Wege zur Vermittlung des Lehrstoffs. Die Erstellung dieser Lehrmaterialien kann allerdings je nach Art und Qualit{\"a}t sehr zeitintensiv sein und f{\"u}r Lehrende einen großen Mehraufwand bedeuten. Im Rahmen eines Kooperationsprojekts zur Erstellung von Lehrvideos f{\"u}r geotechnische Feld- und Laborversuche haben die Autoren dieses Beitrags allerdings die Erfahrung gemacht, dass das gemeinsame, hochschul{\"u}bergreifende Erstellen von Lehrmaterialien viele Vorteile mit sich bringt. Dadurch inspiriert, f{\"u}hrten die Autoren dieses Berichts eine Umfrage unter den deutschsprachigen Geotechnik-Lehrst{\"u}hlen der (Technischen) Universit{\"a}ten und (Fach-)Hochschulen durch. Nach drei Semestern, in denen Lehrveranstaltungen an den Hochschulen aufgrund der Corona-Pandemie {\"u}berwiegend digital durchgef{\"u}hrt werden mussten, war es ein Ziel dieser Umfrage, den Bestand und den Einsatz digitaler Lehrmaterialien im Fachgebiet Geotechnik zu erheben. Ein weiteres Ziel war die Initiierung eines Netzwerks, in dem sich Geotechnik-Professorinnen und -Professoren zu Lehrthemen austauschen k{\"o}nnen und gemeinsam (digitale) Lehrmaterialien erstellen und nutzen. Der vorliegende Beitrag stellt das gemeinsame Lehrprojekt der Autoren vor, pr{\"a}sentiert die Ergebnisse der durchgef{\"u}hrten Umfrage und berichtet {\"u}ber die ersten Aktivit{\"a}ten des neuen Netzwerks.}, language = {de} } @article{VahidpourAlghazaliAkcaetal.2022, author = {Vahidpour, Farnoosh and Alghazali, Yousef and Akca, Sevilay and Hommes, Gregor and Sch{\"o}ning, Michael Josef}, title = {An Enzyme-Based Interdigitated Electrode-Type Biosensor for Detecting Low Concentrations of H₂O₂ Vapor/Aerosol}, series = {Chemosensors}, volume = {10}, journal = {Chemosensors}, number = {6}, publisher = {MDPI}, address = {Basel}, issn = {2227-9040}, doi = {10.3390/chemosensors10060202}, pages = {Arikel 202}, year = {2022}, abstract = {This work introduces a novel method for the detection of H₂O₂ vapor/aerosol of low concentrations, which is mainly applied in the sterilization of equipment in medical industry. Interdigitated electrode (IDE) structures have been fabricated by means of microfabrication techniques. A differential setup of IDEs was prepared, containing an active sensor element (active IDE) and a passive sensor element (passive IDE), where the former was immobilized with an enzymatic membrane of horseradish peroxidase that is selective towards H₂O₂. Changes in the IDEs' capacitance values (active sensor element versus passive sensor element) under H₂O₂ vapor/aerosol atmosphere proved the detection in the concentration range up to 630 ppm with a fast response time (<60 s). The influence of relative humidity was also tested with regard to the sensor signal, showing no cross-sensitivity. The repeatability assessment of the IDE biosensors confirmed their stable capacitive signal in eight subsequent cycles of exposure to H₂O₂ vapor/aerosol. Room-temperature detection of H₂O₂ vapor/aerosol with such miniaturized biosensors will allow a future three-dimensional, flexible mapping of aseptic chambers and help to evaluate sterilization assurance in medical industry.}, language = {en} } @article{HerssensCowburnAlbrachtetal.2022, author = {Herssens, Nolan and Cowburn, James and Albracht, Kirsten and Braunstein, Bjoern and Cazzola, Dario and Colyer, Steffi and Minetti, Alberto E. and Pavei, Gaspare and Rittweger, J{\"o}rn and Weber, Tobias and Green, David A.}, title = {Movement in low gravity environments (MoLo) programme - the MoLo-L.O.O.P. study protocol}, series = {PLOS ONE / Public Library of Science}, volume = {17}, journal = {PLOS ONE / Public Library of Science}, number = {11}, editor = {Cattaneo, Luigi}, publisher = {Plos}, address = {San Francisco}, issn = {1932-6203}, doi = {10.1371/journal.pone.0278051}, pages = {e0278051}, year = {2022}, abstract = {Exposure to prolonged periods in microgravity is associated with deconditioning of the musculoskeletal system due to chronic changes in mechanical stimulation. Given astronauts will operate on the Lunar surface for extended periods of time, it is critical to quantify both external (e.g., ground reaction forces) and internal (e.g., joint reaction forces) loads of relevant movements performed during Lunar missions. Such knowledge is key to predict musculoskeletal deconditioning and determine appropriate exercise countermeasures associated with extended exposure to hypogravity.}, language = {en} } @article{CollPeralesSchulteTiggesRondinoneetal.2022, author = {Coll-Perales, Baldomero and Schulte-Tigges, Joschua and Rondinone, Michele and Gozalvez, Javier and Reke, Michael and Matheis, Dominik and Walter, Thomas}, title = {Prototyping and evaluation of infrastructure-assisted transition of control for cooperative automated vehicles}, series = {IEEE Transactions on Intelligent Transportation Systems}, volume = {23}, journal = {IEEE Transactions on Intelligent Transportation Systems}, number = {7}, publisher = {IEEE}, issn = {1524-9050 (Print)}, doi = {10.1109/TITS.2021.3061085}, pages = {6720 -- 6736}, year = {2022}, abstract = {Automated driving is now possible in diverse road and traffic conditions. However, there are still situations that automated vehicles cannot handle safely and efficiently. In this case, a Transition of Control (ToC) is necessary so that the driver takes control of the driving. Executing a ToC requires the driver to get full situation awareness of the driving environment. If the driver fails to get back the control in a limited time, a Minimum Risk Maneuver (MRM) is executed to bring the vehicle into a safe state (e.g., decelerating to full stop). The execution of ToCs requires some time and can cause traffic disruption and safety risks that increase if several vehicles execute ToCs/MRMs at similar times and in the same area. This study proposes to use novel C-ITS traffic management measures where the infrastructure exploits V2X communications to assist Connected and Automated Vehicles (CAVs) in the execution of ToCs. The infrastructure can suggest a spatial distribution of ToCs, and inform vehicles of the locations where they could execute a safe stop in case of MRM. This paper reports the first field operational tests that validate the feasibility and quantify the benefits of the proposed infrastructure-assisted ToC and MRM management. The paper also presents the CAV and roadside infrastructure prototypes implemented and used in the trials. The conducted field trials demonstrate that infrastructure-assisted traffic management solutions can reduce safety risks and traffic disruptions.}, language = {en} } @misc{OPUS4-10711, title = {Dimensionen 2-2022: Magazin der FH Aachen University of Applied Sciences - Werkstatt Zukunft}, address = {Aachen}, organization = {Fachhochschule Aachen}, pages = {63 Seiten}, year = {2022}, abstract = {Werkstatt Zukunft - Die FH Aachen versteht sich als interdisziplin{\"a}re Ideenschmiede 04| Aufbruch ins Ungewisse 08| Mit Altpapierresten aus der Energiekrise 14| Mehr Power f{\"u}r die Energiewende 20| Pfadfinder im Datendschungel 23| Ein historischer Schritt 24| Gemeinsam vorw{\"a}rts 30| F{\"u}r eine gerechte Hochschule. F{\"u}r alle. 32| Der gr{\"u}ne Reiter 34| Vom Flugsimulator bis zum Roboter 36| Unsere Azubis sind top! 38| WIR sind ein Sportteam! 40| Effizient und sicher: Der Bergbau der Zukunft 46| Mit Sonnenlicht zu sauberem Trinkwasser 48| Neue Brandmeldeanlage f{\"u}r den Dom zu Aachen 50| Auszeichnung f{\"u}r außergew{\"o}hnliches Engagement 52| Neue Ideen f{\"u}r Schloss Lichtenburg 55| Kopfnuss 56| One-Man-Show 60| K{\"a}mpferin f{\"u}r das Sch{\"o}ne 61| Ein charmanter Diplomat 62| Teamplay f{\"u}r die Zukunft 63| Impressum}, language = {de} } @incollection{FissabreWilson2022, author = {Fissabre, Anke and Wilson, Ariane}, title = {Hypotheses on the Tower of Monthoiron: A Built Design of Italian and Leonardian Inspiration in France}, series = {Leonardo da Vinci: l'architettura / Léonard de Vinci : l'architecture}, booktitle = {Leonardo da Vinci: l'architettura / Léonard de Vinci : l'architecture}, editor = {Di Teodoro, Francesco P. and Ferretti, Emanuela and Frommel, Sabine and Schlimme, Hermann}, publisher = {Campisano Editore}, address = {Roma}, isbn = {979-12-80956-00-2}, pages = {287 -- 300}, year = {2022}, language = {mul} } @inproceedings{ChavezBermudezCruzCastanonRuchayetal.2022, author = {Chavez Bermudez, Victor Francisco and Cruz Castanon, Victor Fernando and Ruchay, Marco and Wollert, J{\"o}rg}, title = {Rapid prototyping framework for automation applications based on IO-Link}, series = {Tagungsband AALE 2022: Wissenstransfer im Spannungsfeld von Autonomisierung und Fachkr{\"a}ftemangel}, booktitle = {Tagungsband AALE 2022: Wissenstransfer im Spannungsfeld von Autonomisierung und Fachkr{\"a}ftemangel}, editor = {Leipzig, Hochschule f{\"u}r Technik, Wirtschaft und Kultur}, address = {Leipzig}, isbn = {978-3-910103-00-9}, doi = {10.33968/2022.28}, pages = {8 Seiten}, year = {2022}, abstract = {The development of protype applications with sensors and actuators in the automation industry requires tools that are independent of manufacturer, and are flexible enough to be modified or extended for any specific requirements. Currently, developing prototypes with industrial sensors and actuators is not straightforward. First of all, the exchange of information depends on the industrial protocol that these devices have. Second, a specific configuration and installation is done based on the hardware that is used, such as automation controllers or industrial gateways. This means that the development for a specific industrial protocol, highly depends on the hardware and the software that vendors provide. In this work we propose a rapid-prototyping framework based on Arduino to solve this problem. For this project we have focused to work with the IO-Link protocol. The framework consists of an Arduino shield that acts as the physical layer, and a software that implements the IO-Link Master protocol. The main advantage of such framework is that an application with industrial devices can be rapid-prototyped with ease as its vendor independent, open-source and can be ported easily to other Arduino compatible boards. In comparison, a typical approach requires proprietary hardware, is not easy to port to another system and is closed-source.}, language = {en} } @inproceedings{UlmerMostafaWollert2022, author = {Ulmer, Jessica and Mostafa, Youssef and Wollert, J{\"o}rg}, title = {Digital Twin Academy: From Zero to Hero through individual learning experiences}, series = {Tagungsband AALE 2022: Wissenstransfer im Spannungsfeld von Autonomisierung und Fachkr{\"a}ftemangel}, booktitle = {Tagungsband AALE 2022: Wissenstransfer im Spannungsfeld von Autonomisierung und Fachkr{\"a}ftemangel}, isbn = {978-3-910103-00-9}, doi = {10.33968/2022.33}, url = {http://nbn-resolving.de/urn:nbn:de:bsz:l189-qucosa2-776097}, pages = {1 -- 9}, year = {2022}, abstract = {Digital twins are seen as one of the key technologies of Industry 4.0. Although many research groups focus on digital twins and create meaningful outputs, the technology has not yet reached a broad application in the industry. The main reasons for this imbalance are the complexity of the topic, the lack of specialists, and the unawareness of the twin opportunities. The project "Digital Twin Academy" aims to overcome these barriers by focusing on three actions: Building a digital twin community for discussion and exchange, offering multi-stage training for various knowledge levels, and implementing realworld use cases for deeper insights and guidance. In this work, we focus on creating a flexible learning platform that allows the user to select a training path adjusted to personal knowledge and needs. Therefore, a mix of basic and advanced modules is created and expanded by individual feedback options. The usage of personas supports the selection of the appropriate modules.}, language = {en} } @article{KemptFreyerNagel2022, author = {Kempt, Hendrik and Freyer, Nils and Nagel, Saskia K.}, title = {Justice and the normative standards of explainability in healthcare}, series = {Philosophy \& Technology}, volume = {35}, journal = {Philosophy \& Technology}, number = {Article number: 100}, publisher = {Springer Nature}, address = {Berlin}, doi = {10.1007/s13347-022-00598-0}, pages = {1 -- 19}, year = {2022}, abstract = {Providing healthcare services frequently involves cognitively demanding tasks, including diagnoses and analyses as well as complex decisions about treatments and therapy. From a global perspective, ethically significant inequalities exist between regions where the expert knowledge required for these tasks is scarce or abundant. One possible strategy to diminish such inequalities and increase healthcare opportunities in expert-scarce settings is to provide healthcare solutions involving digital technologies that do not necessarily require the presence of a human expert, e.g., in the form of artificial intelligent decision-support systems (AI-DSS). Such algorithmic decision-making, however, is mostly developed in resource- and expert-abundant settings to support healthcare experts in their work. As a practical consequence, the normative standards and requirements for such algorithmic decision-making in healthcare require the technology to be at least as explainable as the decisions made by the experts themselves. The goal of providing healthcare in settings where resources and expertise are scarce might come with a normative pull to lower the normative standards of using digital technologies in order to provide at least some healthcare in the first place. We scrutinize this tendency to lower standards in particular settings from a normative perspective, distinguish between different types of absolute and relative, local and global standards of explainability, and conclude by defending an ambitious and practicable standard of local relative explainability.}, language = {en} } @article{StaeudleSeynnesLapsetal.2022, author = {St{\"a}udle, Benjamin and Seynnes, Olivier and Laps, Guido and Br{\"u}ggemann, Gert-Peter and Albracht, Kirsten}, title = {Altered gastrocnemius contractile behavior in former achilles tendon rupture patients during walking}, series = {Frontiers in Physiology}, volume = {13}, journal = {Frontiers in Physiology}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-042X}, doi = {10.3389/fphys.2022.792576}, pages = {12 Seiten}, year = {2022}, abstract = {Achilles tendon rupture (ATR) remains associated with functional limitations years after injury. Architectural remodeling of the gastrocnemius medialis (GM) muscle is typically observed in the affected leg and may compensate force deficits caused by a longer tendon. Yet patients seem to retain functional limitations during—low-force—walking gait. To explore the potential limits imposed by the remodeled GM muscle-tendon unit (MTU) on walking gait, we examined the contractile behavior of muscle fascicles during the stance phase. In a cross-sectional design, we studied nine former patients (males; age: 45 ± 9 years; height: 180 ± 7 cm; weight: 83 ± 6 kg) with a history of complete unilateral ATR, approximately 4 years post-surgery. Using ultrasonography, GM tendon morphology, muscle architecture at rest, and fascicular behavior were assessed during walking at 1.5 m⋅s-1 on a treadmill. Walking patterns were recorded with a motion capture system. The unaffected leg served as control. Lower limbs kinematics were largely similar between legs during walking. Typical features of ATR-related MTU remodeling were observed during the stance sub-phases corresponding to series elastic element (SEE) lengthening (energy storage) and SEE shortening (energy release), with shorter GM fascicles (36 and 36\%, respectively) and greater pennation angles (8° and 12°, respectively). However, relative to the optimal fascicle length for force production, fascicles operated at comparable length in both legs. Similarly, when expressed relative to optimal fascicle length, fascicle contraction velocity was not different between sides, except at the time-point of peak series elastic element (SEE) length, where it was 39 ± 49\% lower in the affected leg. Concomitantly, fascicles rotation during contraction was greater in the affected leg during the whole stance-phase, and architectural gear ratios (AGR) was larger during SEE lengthening. Under the present testing conditions, former ATR patients had recovered a relatively symmetrical walking gait pattern. Differences in seen AGR seem to accommodate the profound changes in MTU architecture, limiting the required fascicle shortening velocity. Overall, the contractile behavior of the GM fascicles does not restrict length- or velocity-dependent force potentials during this locomotor task.}, language = {en} } @article{QuittmannAbelAlbrachtetal.2022, author = {Quittmann, Oliver J. and Abel, Thomas and Albracht, Kirsten and Str{\"u}der, Heiko K.}, title = {Biomechanics of all-out handcycling exercise: kinetics, kinematics and muscular activity of a 15-s sprint test in able-bodied participants}, series = {Sports Biomechanics}, volume = {21}, journal = {Sports Biomechanics}, number = {10}, publisher = {Taylor \& Francis}, address = {London}, issn = {1752-6116 (Onlineausgabe)}, doi = {10.1080/14763141.2020.1745266}, pages = {1200 -- 1223}, year = {2022}, abstract = {This study aims to quantify the kinematics, kinetics and muscular activity of all-out handcycling exercise and examine their alterations during the course of a 15-s sprint test. Twelve able-bodied competitive triathletes performed a 15-s all-out sprint test in a recumbent racing handcycle that was attached to an ergometer. During the sprint test, tangential crank kinetics, 3D joint kinematics and muscular activity of 10 muscles of the upper extremity and trunk were examined using a power metre, motion capturing and surface electromyography (sEMG), respectively. Parameters were compared between revolution one (R1), revolution two (R2), the average of revolution 3 to 13 (R3) and the average of the remaining revolutions (R4). Shoulder abduction and internal-rotation increased, whereas maximal shoulder retroversion decreased during the sprint. Except for the wrist angles, angular velocity increased for every joint of the upper extremity. Several muscles demonstrated an increase in muscular activation, an earlier onset of muscular activation in crank cycle and an increased range of activation. During the course of a 15-s all-out sprint test in handcycling, the shoulder muscles and the muscles associated to the push phase demonstrate indications for short-duration fatigue. These findings are helpful to prevent injuries and improve performance in all-out handcycling.}, language = {en} } @article{AngermannGuenthnerHanssenetal.2022, author = {Angermann, Susanne and G{\"u}nthner, Roman and Hanssen, Henner and Lorenz, Georg and Braunisch, Matthias C. and Steubl, Dominik and Matschkal, Julia and Kemmner, Stephan and Hausinger, Renate and Block, Zenonas and Haller, Bernhard and Heemann, Uwe and Kotliar, Konstantin and Grimmer, Timo and Schmaderer, Christoph}, title = {Cognitive impairment and microvascular function in end-stage renal disease}, series = {International Journal of Methods in Psychiatric Research (MPR)}, volume = {31}, journal = {International Journal of Methods in Psychiatric Research (MPR)}, number = {2}, publisher = {Wiley}, issn = {1049-8931 (Print)}, doi = {10.1002/mpr.1909}, pages = {1 -- 10}, year = {2022}, abstract = {Objective Hemodialysis patients show an approximately threefold higher prevalence of cognitive impairment compared to the age-matched general population. Impaired microcirculatory function is one of the assumed causes. Dynamic retinal vessel analysis is a quantitative method for measuring neurovascular coupling and microvascular endothelial function. We hypothesize that cognitive impairment is associated with altered microcirculation of retinal vessels. Methods 152 chronic hemodialysis patients underwent cognitive testing using the Montreal Cognitive Assessment. Retinal microcirculation was assessed by Dynamic Retinal Vessel Analysis, which carries out an examination recording retinal vessels' reaction to a flicker light stimulus under standardized conditions. Results In unadjusted as well as in adjusted linear regression analyses a significant association between the visuospatial executive function domain score of the Montreal Cognitive Assessment and the maximum arteriolar dilation as response of retinal arterioles to the flicker light stimulation was obtained. Conclusion This is the first study determining retinal microvascular function as surrogate for cerebral microvascular function and cognition in hemodialysis patients. The relationship between impairment in executive function and reduced arteriolar reaction to flicker light stimulation supports the involvement of cerebral small vessel disease as contributing factor for the development of cognitive impairment in this patient population and might be a target for noninvasive disease monitoring and therapeutic intervention.}, language = {en} } @article{KotliarOrtnerConradietal.2022, author = {Kotliar, Konstantin and Ortner, Marion and Conradi, Anna and Hacker, Patricia and Hauser, Christine and G{\"u}nthner, Roman and Moser, Michaela and Muggenthaler, Claudia and Diehl-Schmid, Janine and Priller, Josef and Schmaderer, Christoph and Grimmer, Timo}, title = {Altered retinal cerebral vessel oscillation frequencies in Alzheimer's disease compatible with impaired amyloid clearance}, series = {Neurobiology of Aging}, volume = {120}, journal = {Neurobiology of Aging}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0197-4580}, doi = {10.1016/j.neurobiolaging.2022.08.012}, pages = {117 -- 127}, year = {2022}, abstract = {Retinal vessels are similar to cerebral vessels in their structure and function. Moderately low oscillation frequencies of around 0.1 Hz have been reported as the driving force for paravascular drainage in gray matter in mice and are known as the frequencies of lymphatic vessels in humans. We aimed to elucidate whether retinal vessel oscillations are altered in Alzheimer's disease (AD) at the stage of dementia or mild cognitive impairment (MCI). Seventeen patients with mild-to-moderate dementia due to AD (ADD); 23 patients with MCI due to AD, and 18 cognitively healthy controls (HC) were examined using Dynamic Retinal Vessel Analyzer. Oscillatory temporal changes of retinal vessel diameters were evaluated using mathematical signal analysis. Especially at moderately low frequencies around 0.1 Hz, arterial oscillations in ADD and MCI significantly prevailed over HC oscillations and correlated with disease severity. The pronounced retinal arterial vasomotion at moderately low frequencies in the ADD and MCI groups would be compatible with the view of a compensatory upregulation of paravascular drainage in AD and strengthen the amyloid clearance hypothesis.}, language = {en} } @article{WerfelGuenthnerHapfelmeieretal.2022, author = {Werfel, Stanislas and G{\"u}nthner, Roman and Hapfelmeier, Alexander and Hanssen, Henner and Kotliar, Konstantin and Heemann, Uwe and Schmaderer, Christoph}, title = {Identification of cardiovascular high-risk groups from dynamic retinal vessel signals using untargeted machine learning}, series = {Cardiovascular Research}, volume = {118}, journal = {Cardiovascular Research}, number = {2}, editor = {Guzik, Tomasz J.}, publisher = {Oxford University Press}, address = {Oxford}, issn = {0008-6363}, doi = {10.1093/cvr/cvab040}, pages = {612 -- 621}, year = {2022}, abstract = {Dynamic retinal vessel analysis (DVA) provides a non-invasive way to assess microvascular function in patients and potentially to improve predictions of individual cardiovascular (CV) risk. The aim of our study was to use untargeted machine learning on DVA in order to improve CV mortality prediction and identify corresponding response alterations.}, language = {en} } @phdthesis{Biewendt2022, author = {Biewendt, Marcel}, title = {Socio-Economic challenges in sustainability and resource management}, publisher = {Hungarian University of Agriculture and Life Sciences}, pages = {160 Seiten}, year = {2022}, abstract = {This dissertation uses in first stage a macroeconomic investigation to examine the dependence, influence and corruption of socio-economic development through effects of sustainability and resource management. The conducted research found that the state's dependence on its citizens decreases when the state's sources of revenue are largely detached and independent of the citizens' financial resources. In this case, financial resources are taxes and duties provided by the citizens. One possible consequence is the restriction of state investment in its citizens. Both the qualitative literature review and the quantitative data analysis revealed a negative correlation between socio-economic development and the resource economy's share of GDP for the period under study. The microeconomic investigation was primarily conducted through an intensive literature review. It was shown that the rebound effect as such is already very well researched. However, it also became clear that avoidance strategies for the rebound effect and links to sustainability initiatives are scarce or non-existent. The need for a redesign of the impact analysis with regard to technological innovations and their influence on resource consumption and resource management has become clear on the basis of the present study. Further, emerging and developing countries in particular, which will be confronted in the foreseeable future not only with the fundamental problems of resource abundance in the overall economic context, but also with the issues of their sustainable use, should be confronted with these problems as early as possible in order to find solutions in a timely manner.}, language = {de} } @article{UysalCreutzFiratetal.2022, author = {Uysal, Karya and Creutz, Till and Firat, Ipek Seda and Artmann, Gerhard and Teusch, Nicole and Temiz Artmann, Ayseg{\"u}l}, title = {Bio-functionalized ultra-thin, large-area and waterproof silicone membranes for biomechanical cellular loading and compliance experiments}, series = {Polymers}, volume = {14}, journal = {Polymers}, number = {11}, publisher = {MDPI}, address = {Basel}, issn = {2073-4360}, pages = {2213}, year = {2022}, abstract = {Biocompatibility, flexibility and durability make polydimethylsiloxane (PDMS) membranes top candidates in biomedical applications. CellDrum technology uses large area, <10 µm thin membranes as mechanical stress sensors of thin cell layers. For this to be successful, the properties (thickness, temperature, dust, wrinkles, etc.) must be precisely controlled. The following parameters of membrane fabrication by means of the Floating-on-Water (FoW) method were investigated: (1) PDMS volume, (2) ambient temperature, (3) membrane deflection and (4) membrane mechanical compliance. Significant differences were found between all PDMS volumes and thicknesses tested (p < 0.01). They also differed from the calculated values. At room temperatures between 22 and 26 °C, significant differences in average thickness values were found, as well as a continuous decrease in thicknesses within a 4 °C temperature elevation. No correlation was found between the membrane thickness groups (between 3-4 µm) in terms of deflection and compliance. We successfully present a fabrication method for thin bio-functionalized membranes in conjunction with a four-step quality management system. The results highlight the importance of tight regulation of production parameters through quality control. The use of membranes described here could also become the basis for material testing on thin, viscous layers such as polymers, dyes and adhesives, which goes far beyond biological applications.}, language = {en} } @article{BergmannGoettenBraunetal.2022, author = {Bergmann, Ole and G{\"o}tten, Falk and Braun, Carsten and Janser, Frank}, title = {Comparison and evaluation of blade element methods against RANS simulations and test data}, series = {CEAS Aeronautical Journal}, volume = {13}, journal = {CEAS Aeronautical Journal}, publisher = {Springer}, address = {Wien}, issn = {1869-5590 (Online)}, doi = {10.1007/s13272-022-00579-1}, pages = {535 -- 557}, year = {2022}, abstract = {This paper compares several blade element theory (BET) method-based propeller simulation tools, including an evaluation against static propeller ground tests and high-fidelity Reynolds-Average Navier Stokes (RANS) simulations. Two proprietary propeller geometries for paraglider applications are analysed in static and flight conditions. The RANS simulations are validated with the static test data and used as a reference for comparing the BET in flight conditions. The comparison includes the analysis of varying 2D aerodynamic airfoil parameters and different induced velocity calculation methods. The evaluation of the BET propeller simulation tools shows the strength of the BET tools compared to RANS simulations. The RANS simulations underpredict static experimental data within 10\% relative error, while appropriate BET tools overpredict the RANS results by 15-20\% relative error. A variation in 2D aerodynamic data depicts the need for highly accurate 2D data for accurate BET results. The nonlinear BET coupled with XFOIL for the 2D aerodynamic data matches best with RANS in static operation and flight conditions. The novel BET tool PropCODE combines both approaches and offers further correction models for highly accurate static and flight condition results.}, language = {en} } @inproceedings{Gaigall2022, author = {Gaigall, Daniel}, title = {On Consistent Hypothesis Testing In General Hilbert Spaces}, series = {Proceedings of the 4th International Conference on Statistics: Theory and Applications (ICSTA'22)}, booktitle = {Proceedings of the 4th International Conference on Statistics: Theory and Applications (ICSTA'22)}, publisher = {Avestia Publishing}, address = {Orl{\´e}ans, Kanada}, doi = {10.11159/icsta22.157}, pages = {Paper No. 157}, year = {2022}, abstract = {Inference on the basis of high-dimensional and functional data are two topics which are discussed frequently in the current statistical literature. A possibility to include both topics in a single approach is working on a very general space for the underlying observations, such as a separable Hilbert space. We propose a general method for consistently hypothesis testing on the basis of random variables with values in separable Hilbert spaces. We avoid concerns with the curse of dimensionality due to a projection idea. We apply well-known test statistics from nonparametric inference to the projected data and integrate over all projections from a specific set and with respect to suitable probability measures. In contrast to classical methods, which are applicable for real-valued random variables or random vectors of dimensions lower than the sample size, the tests can be applied to random vectors of dimensions larger than the sample size or even to functional and high-dimensional data. In general, resampling procedures such as bootstrap or permutation are suitable to determine critical values. The idea can be extended to the case of incomplete observations. Moreover, we develop an efficient algorithm for implementing the method. Examples are given for testing goodness-of-fit in a one-sample situation in [1] or for testing marginal homogeneity on the basis of a paired sample in [2]. Here, the test statistics in use can be seen as generalizations of the well-known Cram{\´e}rvon-Mises test statistics in the one-sample and two-samples case. The treatment of other testing problems is possible as well. By using the theory of U-statistics, for instance, asymptotic null distributions of the test statistics are obtained as the sample size tends to infinity. Standard continuity assumptions ensure the asymptotic exactness of the tests under the null hypothesis and that the tests detect any alternative in the limit. Simulation studies demonstrate size and power of the tests in the finite sample case, confirm the theoretical findings, and are used for the comparison with concurring procedures. A possible application of the general approach is inference for stock market returns, also in high data frequencies. In the field of empirical finance, statistical inference of stock market prices usually takes place on the basis of related log-returns as data. In the classical models for stock prices, i.e., the exponential L{\´e}vy model, Black-Scholes model, and Merton model, properties such as independence and stationarity of the increments ensure an independent and identically structure of the data. Specific trends during certain periods of the stock price processes can cause complications in this regard. In fact, our approach can compensate those effects by the treatment of the log-returns as random vectors or even as functional data.}, language = {en} } @incollection{EngelmannBaumann2022, author = {Engelmann, Ulrich M. and Baumann, Martin}, title = {Moderationsexpertise f{\"u}r QMBs - das Mindset}, series = {Qualit{\"a}tsmanagement im Gesundheitswesen}, booktitle = {Qualit{\"a}tsmanagement im Gesundheitswesen}, editor = {Herbig, Nicola and Poppelreuter, Stefan}, edition = {59. Update}, publisher = {T{\"U}V-Verlag}, address = {K{\"o}ln}, isbn = {978-3-8249-0714-4}, pages = {Kapitel 10814}, year = {2022}, abstract = {Teamsitzungen, Arbeitsgruppentreffen, Kickoffs und Meetings - sie alle werden mit dem Ziel durchgef{\"u}hrt, innerhalb einer vorgegebenen Zeitspanne ein gemeinsames Arbeitsziel zu erreichen. Damit die Zielerreichung auch bei komplexeren Arbeitsauftr{\"a}gen nicht vom Zufall abh{\"a}ngt, empfiehlt es sich, die Leitung des Ablaufs einem Moderator zu {\"u}bertragen. In diesem Beitrag einer mehrteiligen Serie wird beschrieben, {\"u}ber welches Mindset der Moderator verf{\"u}gen sollte, welche grunds{\"a}tzlichen Methoden hilfreich sind und was bei der Onlinemoderation im Besonderen zu beachten ist.}, language = {de} } @inproceedings{Maurer2022, author = {Maurer, Florian}, title = {Framework to provide a simulative comparison of different energy market designs}, series = {Energy Informatics}, volume = {5}, booktitle = {Energy Informatics}, number = {2, Article number: 12}, publisher = {Springer Nature}, issn = {2520-8942}, doi = {10.1186/s42162-022-00215-6}, pages = {18 -- 20}, year = {2022}, abstract = {Useful market simulations are key to the evaluation of diferent market designs existing of multiple market mechanisms or rules. Yet a simulation framework which has a comparison of diferent market mechanisms in mind was not found. The need to create an objective view on different sets of market rules while investigating meaningful agent strategies concludes that such a simulation framework is needed to advance the research on this subject. An overview of diferent existing market simulation models is given which also shows the research gap and the missing capabilities of those systems. Finally, a methodology is outlined how a novel market simulation which can answer the research questions can be developed.}, language = {en} } @inproceedings{HorikawaAshikagaYamaguchietal.2022, author = {Horikawa, Atsushi and Ashikaga, Mitsugu and Yamaguchi, Masato and Ogino, Tomoyuki and Aoki, Shigeki and Wirsum, Manfred and Funke, Harald and Kusterer, Karsten}, title = {Combined heat and power supply demonstration of Micro-Mix Hydrogen Combustion Applied to M1A-17 Gas Turbine}, series = {Proceedings of ASME Turbo Expo 2022: Turbomachinery Technical Conference and Exposition (GT2022) (Volume 3A)}, booktitle = {Proceedings of ASME Turbo Expo 2022: Turbomachinery Technical Conference and Exposition (GT2022) (Volume 3A)}, publisher = {American Society of Mechanical Engineers}, address = {Fairfield}, isbn = {978-0-7918-8599-4}, doi = {10.1115/GT2022-81620}, pages = {7 Seiten}, year = {2022}, abstract = {Kawasaki Heavy Industries, Ltd. (KHI), Aachen University of Applied Sciences, and B\&B-AGEMA GmbH have investigated the potential of low NOx micro-mix (MMX) hydrogen combustion and its application to an industrial gas turbine combustor. Engine demonstration tests of a MMX combustor for the M1A-17 gas turbine with a co-generation system were conducted in the hydrogen-fueled power generation plant in Kobe City, Japan. This paper presents the results of the commissioning test and the combined heat and power (CHP) supply demonstration. In the commissioning test, grid interconnection, loading tests and load cut-off tests were successfully conducted. All measurement results satisfied the Japanese environmental regulation values. Dust and soot as well as SOx were not detected. The NOx emissions were below 84 ppmv at 15 \% O2. The noise level at the site boundary was below 60 dB. The vibration at the site boundary was below 45 dB. During the combined heat and power supply demonstration, heat and power were supplied to neighboring public facilities with the MMX combustion technology and 100 \% hydrogen fuel. The electric power output reached 1800 kW at which the NOx emissions were 72 ppmv at 15 \% O2, and 60 \%RH. Combustion instabilities were not observed. The gas turbine efficiency was improved by about 1 \% compared to a non-premixed type combustor with water injection as NOx reduction method. During a total equivalent operation time of 1040 hours, all combustor parts, the M1A-17 gas turbine as such, and the co-generation system were without any issues.}, language = {en} } @inproceedings{Butenweg2022, author = {Butenweg, Christoph}, title = {Seismic design and evaluation of industrial facilities}, series = {The Third European Conference on Earthquake Engineering and Seismology}, booktitle = {The Third European Conference on Earthquake Engineering and Seismology}, editor = {Vacareanu, Radu and Ionescu, Constantin}, publisher = {Springer}, address = {Cham}, isbn = {978-3-031-15103-3}, issn = {2524-342X}, doi = {10.1007/978-3-031-15104-0}, pages = {449 -- 464}, year = {2022}, abstract = {Industrial facilities must be thoroughly designed to withstand seismic actions as they exhibit an increased loss potential due to the possibly wideranging damage consequences and the valuable process engineering equipment. Past earthquakes showed the social and political consequences of seismic damage to industrial facilities and sensitized the population and politicians worldwide for the possible hazard emanating from industrial facilities. However, a holistic approach for the seismic design of industrial facilities can presently neither be found in national nor in international standards. The introduction of EN 1998-4 of the new generation of Eurocode 8 will improve the normative situation with specific seismic design rules for silos, tanks and pipelines and secondary process components. The article presents essential aspects of the seismic design of industrial facilities based on the new generation of Eurocode 8 using the example of tank structures and secondary process components. The interaction effects of the process components with the primary structure are illustrated by means of the experimental results of a shaking table test of a three story moment resisting steel frame with different process components. Finally, an integrated approach of digital plant models based on building information modelling (BIM) and structural health monitoring (SHM) is presented, which provides not only a reliable decision-making basis for operation, maintenance and repair but also an excellent tool for rapid assessment of seismic damage.}, language = {en} } @inproceedings{MorandiButenwegBreisetal.2022, author = {Morandi, Paolo and Butenweg, Christoph and Breis, Khaled and Beyer, Katrin and Magenes, Guido}, title = {Behaviour factor q for the seismic design of URM buildings}, series = {The Third European Conference on Earthquake Engineering and Seismology}, booktitle = {The Third European Conference on Earthquake Engineering and Seismology}, editor = {Arion, Christian and Scupin, Alexandra and Ţigănescu, Alexandru}, isbn = {978-973-100-533-1}, pages = {1184 -- 1194}, year = {2022}, abstract = {Recent earthquakes showed that low-rise URM buildings following codecompliant seismic design and details behaved in general very well without substantial damages. Although advances in simulation tools make nonlinear calculation methods more readily accessible to designers, linear analyses will still be the standard design method for years to come. The present paper aims to improve the linear seismic design method by providing a proper definition of the q-factor of URM buildings. Values of q-factors are derived for low-rise URM buildings with rigid diaphragms, with reference to modern structural configurations realized in low to moderate seismic areas of Italy and Germany. The behaviour factor components for deformation and energy dissipation capacity and for overstrength due to the redistribution of forces are derived by means of pushover analyses. As a result of the investigations, rationally based values of the behaviour factor q to be used in linear analyses in the range of 2.0 to 3.0 are proposed.}, language = {en} } @article{KaulenSchwabedalSchneideretal.2022, author = {Kaulen, Lars and Schwabedal, Justus T. C. and Schneider, Jules and Ritter, Philipp and Bialonski, Stephan}, title = {Advanced sleep spindle identification with neural networks}, series = {Scientific Reports}, volume = {12}, journal = {Scientific Reports}, number = {Article number: 7686}, publisher = {Springer Nature}, address = {London}, issn = {2045-2322}, doi = {10.1038/s41598-022-11210-y}, pages = {1 -- 10}, year = {2022}, abstract = {Sleep spindles are neurophysiological phenomena that appear to be linked to memory formation and other functions of the central nervous system, and that can be observed in electroencephalographic recordings (EEG) during sleep. Manually identified spindle annotations in EEG recordings suffer from substantial intra- and inter-rater variability, even if raters have been highly trained, which reduces the reliability of spindle measures as a research and diagnostic tool. The Massive Online Data Annotation (MODA) project has recently addressed this problem by forming a consensus from multiple such rating experts, thus providing a corpus of spindle annotations of enhanced quality. Based on this dataset, we present a U-Net-type deep neural network model to automatically detect sleep spindles. Our model's performance exceeds that of the state-of-the-art detector and of most experts in the MODA dataset. We observed improved detection accuracy in subjects of all ages, including older individuals whose spindles are particularly challenging to detect reliably. Our results underline the potential of automated methods to do repetitive cumbersome tasks with super-human performance.}, language = {en} } @incollection{AkimbekovDigelRazzaque2022, author = {Akimbekov, Nuraly S. and Digel, Ilya and Razzaque, Mohammed S.}, title = {Role of vitamins in maintaining structure and function of intestinal microbiome}, series = {Comprehensive Gut Microbiota}, booktitle = {Comprehensive Gut Microbiota}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {978-0-12-822036-8}, doi = {10.1016/B978-0-12-819265-8.00043-7}, pages = {320 -- 334}, year = {2022}, abstract = {The recent advances in microbiology have shed light on understanding the role of vitamins beyond the nutritional range. Vitamins are critical in contributing to healthy biodiversity and maintaining the proper function of gut microbiota. The sharing of vitamins among bacterial populations promotes stability in community composition and diversity; however, this balance becomes disturbed in various pathologies. Here, we overview and analyze the ability of different vitamins to selectively and specifically induce changes in the intestinal microbial community. Some schemes and regularities become visible, which may provide new insights and avenues for therapeutic management and functional optimization of the gut microbiota.}, language = {en} } @incollection{GkatzogiasVeljkovivPohorylesetal.2022, author = {Gkatzogias, Konstantinos and Veljkoviv, Ana and Pohoryles, Daniel A. and Tsionis, Georgios and Bournas, Dionysios A. and Crowley, Helen and Norl{\´e}n, Hedvig and Butenweg, Christoph and Gervasio, Helena and Manfredi, Vincenzo and Masi, Angelo and Zaharieva, Roumiana}, title = {Policy practice and regional impact assessment for building renovation}, series = {REEBUILD Integrated Techniques for the Seismic Strengthening \& Energy Efficiency of Existing Buildings}, booktitle = {REEBUILD Integrated Techniques for the Seismic Strengthening \& Energy Efficiency of Existing Buildings}, editor = {Gkatzogias, Konstantinos and Tsionis, Georgios}, publisher = {Publications Office of the European Union}, address = {Luxembourg}, isbn = {978-92-76-60454-9}, issn = {1831-9424}, doi = {10.2760/883122}, pages = {1 -- 68}, year = {2022}, abstract = {The work presented in this report provides scientific support to building renovation policies in the EU by promoting a holistic point of view on the topic. Integrated renovation can be seen as a nexus between European policies on disaster resilience, energy efficiency and circularity in the building sector. An overview of policy measures for the seismic and energy upgrading of buildings across EU Member States identified only a few available measures for combined upgrading. Regulatory framework, financial instruments and digital tools similar to those for energy renovation, together with awareness and training may promote integrated renovation. A framework for regional prioritisation of building renovation was put forward, considering seismic risk, energy efficiency, and socioeconomic vulnerability independently and in an integrated way. Results indicate that prioritisation of building renovation is a multidimensional problem. Depending on priorities, different integrated indicators should be used to inform policies and accomplish the highest relative or most spread impact across different sectors. The framework was further extended to assess the impact of renovation scenarios across the EU with a focus on priority regions. Integrated renovation can provide a risk-proofed, sustainable, and inclusive built environment, presenting an economic benefit in the order of magnitude of the highest benefit among the separate interventions. Furthermore, it presents the unique capability of reducing fatalities and energy consumption at the same time and, depending on the scenario, to a greater extent.}, language = {en} } @incollection{WeberBomholtButenweg2022, author = {Weber, Felix and Bomholt, Frederik and Butenweg, Christoph}, title = {Erdbeben- und Schwingungsschutz von Bauwerken}, series = {2023 BetonKalender: Wasserundurchl{\"a}ssiger Beton, Br{\"u}ckenbau}, booktitle = {2023 BetonKalender: Wasserundurchl{\"a}ssiger Beton, Br{\"u}ckenbau}, editor = {Bergmeister, Konrad and Fingerloos, Frank and W{\"o}rner, Johann-Dietrich}, publisher = {Ernst \& Sohn}, address = {Berlin}, isbn = {9783433611180}, doi = {10.1002/9783433611180.ch16}, pages = {779 -- 859}, year = {2022}, abstract = {Dieser Beitrag beschreibt die herk{\"o}mmlichen Maßnahmen wie die Kapazit{\"a}tsbemessung der Tragwerksstruktur, die Isolation des Bauwerks mittels Basisisolatoren, die D{\"a}mpfungserh{\"o}hung der Struktur mittels Inter-Story-D{\"a}mpfern und die Schwingungsreduktion mittels Schwingungstilgern gegen Einwirkungen durch Erdbeben, Wind, Verkehr und Personen auf die Bauwerke. Erg{\"a}nzend wird die erdbebengerechte Auslegung und Isolation von nichttragenden Bauteilen behandelt. F{\"u}r die betrachteten Systeme werden die Bewegungsdifferenzialgleichungen unter Ber{\"u}cksichtigung der wesentlichen Nichtlinearit{\"a}ten angegeben. Die vorgestellten Weiterentwicklungen in den Bereichen der Basisisolatoren, D{\"a}mpfern und Schwingungstilgern zeigen, dass das modellbasierte Design mittels Simulation ein sehr effektives, {\"o}konomisches und dank der heutigen Computerleistung auch zeiteffizientes Werkzeug darstellt.}, language = {de} } @inproceedings{EggertKriska2022, author = {Eggert, Mathias and Kriska, Melina}, title = {Gamification for software development processes - relevant affordances and design principles}, series = {Proceedings of the 55th Hawaii International Conference on System Sciences}, booktitle = {Proceedings of the 55th Hawaii International Conference on System Sciences}, publisher = {HICSS Publishing}, address = {Honolulu}, isbn = {978-0-9981331-5-7}, doi = {10.24251/HICSS.2022.200}, pages = {1614 -- 1623}, year = {2022}, abstract = {A Gamified Information System (GIS) implements game concepts and elements, such as affordances and game design principles to motivate people. Based on the idea to develop a GIS to increase the motivation of software developers to perform software quality tasks, the research work at hand aims at investigating relevant requirements from that target group. Therefore, 14 interviews with software development experts are conducted and analyzed. According to the results, software developers prefer the affordances points, narrative storytelling in a multiplayer and a round-based setting. Furthermore, six design principles for the development of a GIS are derived.}, language = {en} } @article{HeinEubanksLingametal.2022, author = {Hein, Andreas M. and Eubanks, T. Marshall and Lingam, Manasvi and Hibberd, Adam and Fries, Dan and Schneider, Jean and Kervella, Pierre and Kennedy, Robert and Perakis, Nikolaos and Dachwald, Bernd}, title = {Interstellar now! Missions to explore nearby interstellar objects}, series = {Advances in Space Research}, volume = {69}, journal = {Advances in Space Research}, number = {1}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0273-1177}, doi = {10.1016/j.asr.2021.06.052}, pages = {402 -- 414}, year = {2022}, abstract = {The recently discovered first hyperbolic objects passing through the Solar System, 1I/'Oumuamua and 2I/Borisov, have raised the question about near term missions to Interstellar Objects. In situ spacecraft exploration of these objects will allow the direct determination of both their structure and their chemical and isotopic composition, enabling an entirely new way of studying small bodies from outside our solar system. In this paper, we map various Interstellar Object classes to mission types, demonstrating that missions to a range of Interstellar Object classes are feasible, using existing or near-term technology. We describe flyby, rendezvous and sample return missions to interstellar objects, showing various ways to explore these bodies characterizing their surface, dynamics, structure and composition. Their direct exploration will constrain their formation and history, situating them within the dynamical and chemical evolution of the Galaxy. These mission types also provide the opportunity to explore solar system bodies and perform measurements in the far outer solar system.}, language = {en} } @incollection{AkimbekovDigelSherelkhanetal.2022, author = {Akimbekov, Nuraly S. and Digel, Ilya and Sherelkhan, Dinara K. and Razzaque, Mohammed S.}, title = {Vitamin D and Phosphate Interactions in Health and Disease}, series = {Phosphate Metabolism}, booktitle = {Phosphate Metabolism}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-91621-3}, doi = {10.1007/978-3-030-91623-7_5}, pages = {37 -- 46}, year = {2022}, abstract = {Vitamin D plays an essential role in calcium and inorganic phosphate (Pi) homeostasis, maintaining their optimal levels to assure adequate bone mineralization. Vitamin D, as calcitriol (1,25(OH)2D), not only increases intestinal calcium and phosphate absorption but also facilitates their renal reabsorption, leading to elevated serum calcium and phosphate levels. The interaction of 1,25(OH)2D with its receptor (VDR) increases the efficiency of intestinal absorption of calcium to 30-40\% and phosphate to nearly 80\%. Serum phosphate levels can also influence 1,25 (OH)2D and fibroblast growth factor 23 (FGF23) levels, i.e., higher phosphate concentrations suppress vitamin D activation and stimulate parathyroid hormone (PTH) release, while a high FGF23 serum level leads to reduced vitamin D synthesis. In the vitamin D-deficient state, the intestinal calcium absorption decreases and the secretion of PTH increases, which in turn causes the stimulation of 1,25(OH)2D production, resulting in excessive urinary phosphate loss. Maintenance of phosphate homeostasis is essential as hyperphosphatemia is a risk factor of cardiovascular calcification, chronic kidney diseases (CKD), and premature aging, while hypophosphatemia is usually associated with rickets and osteomalacia. This chapter elaborates on the possible interactions between vitamin D and phosphate in health and disease.}, language = {en} } @inproceedings{ZaehlBiewendtWolfetal.2022, author = {Z{\"a}hl, Philipp M. and Biewendt, Marcel and Wolf, Martin R. and Eggert, Mathias}, title = {Requirements for competence developing games in the environment of SE Competence Development}, series = {AKWI-Tagungsband zur 35. AKWI-Jahrestagung}, booktitle = {AKWI-Tagungsband zur 35. AKWI-Jahrestagung}, publisher = {GITO}, address = {Berlin}, isbn = {978-3-95545-409-8}, doi = {10.30844/AKWI_2022_05}, pages = {73 -- 88}, year = {2022}, abstract = {Many of today's factors make software development more and more complex, such as time pressure, new technologies, IT security risks, et cetera. Thus, a good preparation of current as well as future software developers in terms of a good software engineering education becomes progressively important. As current research shows, Competence Developing Games (CDGs) and Serious Games can offer a potential solution. This paper identifies the necessary requirements for CDGs to be conducive in principle, but especially in software engineering (SE) education. For this purpose, the current state of research was summarized in the context of a literature review. Afterwards, some of the identified requirements as well as some additional requirements were evaluated by a survey in terms of subjective relevance.}, language = {en} } @article{KubalskiButenwegElDeib2022, author = {Kubalski, Thomas and Butenweg, Christoph and El-Deib, Khaled}, title = {Vereinfachte Ber{\"u}cksichtigung der Rahmentragwirkung in Mauerwerksgeb{\"a}uden}, series = {Bautechnik}, volume = {99}, journal = {Bautechnik}, number = {12}, editor = {Jesse, Dirk}, publisher = {Ernst \& Sohn}, address = {Berlin}, issn = {0932-8351}, doi = {10.1002/bate.202200081}, pages = {865 -- 928}, year = {2022}, abstract = {Aufgrund der gestiegenen Anforderungen durch h{\"o}here Ein-wirkungen aus Wind und Erdbeben ist eine Verbesserung und Optimierung der Berechnungs- und Bemessungsans{\"a}tze f{\"u}r Mauerwerksbauten erforderlich. Eine bessere Ausnutzung der Tragwerksreserven ist durch die Ber{\"u}cksichtigung der Rah-mentragwirkung mit einer Aktivierung der Deckenscheiben in den Rechenmodellen m{\"o}glich, die in der Praxis aufgrund der Komplexit{\"a}t der Wand-Decken-Interaktion bislang nicht aus-genutzt wird. Im vorliegenden Aufsatz wird ein vereinfachter Ansatz auf Grundlage der mitwirkenden Plattenbreite von Schubw{\"a}nden aus Mauerwerk vorgestellt, der die wesentli-chen Einfl ussfaktoren in parametrisierten Tabellen erfasst. Damit steht den Tragwerksplanern ein einfach anwendbares Werkzeug zur Verf{\"u}gung, um die Rahmentragwirkung in der Mauerwerksbemessung anzusetzen.}, language = {de} } @inproceedings{WeissHeslenfeldSaeweetal.2022, author = {Weiss, Christian and Heslenfeld, Jonas and Saewe, Jasmin Kathrin and Bremen, Sebastian and H{\"a}fner, Constantin Leon}, title = {Investigation on the influence of powder humidity in Laser Powder Bed Fusion (LPBF)}, series = {Procedia CIRP 12th CIRP Conference on Photonic Technologies [LANE 2022]}, volume = {111}, booktitle = {Procedia CIRP 12th CIRP Conference on Photonic Technologies [LANE 2022]}, publisher = {Elsevier}, address = {Amsterdam}, issn = {2212-8271}, doi = {10.1016/j.procir.2022.08.102}, pages = {115 -- 120}, year = {2022}, abstract = {In the Laser Powder Bed Fusion (LPBF) process, parts are built out of metal powder material by exposure of a laser beam. During handling operations of the powder material, several influencing factors can affect the properties of the powder material and therefore directly influence the processability during manufacturing. Contamination by moisture due to handling operations is one of the most critical aspects of powder quality. In order to investigate the influences of powder humidity on LPBF processing, four materials (AlSi10Mg, Ti6Al4V, 316L and IN718) are chosen for this study. The powder material is artificially humidified, subsequently characterized, manufactured into cubic samples in a miniaturized process chamber and analyzed for their relative density. The results indicate that the processability and reproducibility of parts made of AlSi10Mg and Ti6Al4V are susceptible to humidity, while IN718 and 316L are barely influenced.}, language = {en} } @inproceedings{EggertDyong2022, author = {Eggert, Mathias and Dyong, Julian}, title = {Applying process mining in small and medium sized IT enterprises - challenges and guidelines}, series = {Business Process Management, 20th International Conference, BPM 2022, Proceedings}, booktitle = {Business Process Management, 20th International Conference, BPM 2022, Proceedings}, publisher = {Springer}, address = {Cham}, isbn = {978-3-031-16103-2}, doi = {10.1007/978-3-031-16103-2_11}, pages = {125 -- 142}, year = {2022}, abstract = {Process mining gets more and more attention even outside large enterprises and can be a major benefit for small and medium sized enterprises (SMEs) to gain competitive advantages. Applying process mining is challenging, particularly for SMEs because they have less resources and process maturity. So far, IS researchers analyzed process mining challenges with a focus on larger companies. This paper investigates the application of process mining by means of a case study and sheds light into the particular challenges of an IT SME. The results reveal 13 SME process mining challenges and seven guidelines to address them. In this way, the paper contributes to the understanding of process mining application in SME and shows similarities and differences to larger companies.}, language = {en} } @article{vonHaefenKrautwaldStolleetal.2022, author = {von H{\"a}fen, Hajo and Krautwald, Clemens and Stolle, Jacob and Bung, Daniel Bernhard and Goseberg, Nils}, title = {Overland flow of broken solitary waves over a two-dimensional coastal plane}, series = {Coastal Engineering}, volume = {175}, journal = {Coastal Engineering}, number = {August}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1872-7379}, doi = {10.1016/j.coastaleng.2022.104125}, pages = {14 Seiten}, year = {2022}, abstract = {Landslides, rock falls or related subaerial and subaqueous mass slides can generate devastating impulse waves in adjacent waterbodies. Such waves can occur in lakes and fjords, or due to glacier calving in bays or at steep ocean coastlines. Infrastructure and residential houses along coastlines of those waterbodies are often situated on low elevation terrain, and are potentially at risk from inundation. Impulse waves, running up a uniform slope and generating an overland flow over an initially dry adjacent horizontal plane, represent a frequently found scenario, which needs to be better understood for disaster planning and mitigation. This study presents a novel set of large-scale flume test focusing on solitary waves propagating over a 1:14.5 slope and breaking onto a horizontal section. Examining the characteristics of overland flow, this study gives, for the first time, insight into the fundamental process of overland flow of a broken solitary wave: its shape and celerity, as well as its momentum when wave breaking has taken place beforehand.}, language = {en} } @article{FalkenbergRahbaFischeretal.2022, author = {Falkenberg, Fabian and Rahba, Jade and Fischer, David and Bott, Michael and Bongaerts, Johannes and Siegert, Petra}, title = {Biochemical characterization of a novel oxidatively stable, halotolerant, and high-alkaline subtilisin from Alkalihalobacillus okhensis Kh10-101T}, series = {FEBS Open Bio}, volume = {12}, journal = {FEBS Open Bio}, number = {10}, publisher = {Wiley}, address = {Hoboken, NJ}, issn = {2211-5463}, doi = {10.1002/2211-5463.13457}, pages = {1729 -- 1746}, year = {2022}, abstract = {Halophilic and halotolerant microorganisms represent a promising source of salt-tolerant enzymes suitable for various biotechnological applications where high salt concentrations would otherwise limit enzymatic activity. Considering the current growing enzyme market and the need for more efficient and new biocatalysts, the present study aimed at the characterization of a high-alkaline subtilisin from Alkalihalobacillus okhensis Kh10-101T. The protease gene was cloned and expressed in Bacillus subtilis DB104. The recombinant protease SPAO with 269 amino acids belongs to the subfamily of high-alkaline subtilisins. The biochemical characteristics of purified SPAO were analyzed in comparison with subtilisin Carlsberg, Savinase, and BPN'. SPAO, a monomer with a molecular mass of 27.1 kDa, was active over a wide range of pH 6.0-12.0 and temperature 20-80 °C, optimally at pH 9.0-9.5 and 55 °C. The protease is highly oxidatively stable to hydrogen peroxide and retained 58\% of residual activity when incubated at 10 °C with 5\% (v/v) H2O2 for 1 h while stimulated at 1\% (v/v) H2O2. Furthermore, SPAO was very stable and active at NaCl concentrations up to 5.0 m. This study demonstrates the potential of SPAO for biotechnological applications in the future.}, language = {en} } @article{TopcuMadabhushiStaat2022, author = {Top{\c{c}}u, Murat and Madabhushi, Gopal S.P. and Staat, Manfred}, title = {A generalized shear-lag theory for elastic stress transfer between matrix and fibres having a variable radius}, series = {International Journal of Solids and Structures}, volume = {239-240}, journal = {International Journal of Solids and Structures}, number = {Art. No. 111464}, publisher = {Elsevier}, address = {New York, NY}, issn = {0020-7683}, doi = {10.1016/j.ijsolstr.2022.111464}, year = {2022}, abstract = {A generalized shear-lag theory for fibres with variable radius is developed to analyse elastic fibre/matrix stress transfer. The theory accounts for the reinforcement of biological composites, such as soft tissue and bone tissue, as well as for the reinforcement of technical composite materials, such as fibre-reinforced polymers (FRP). The original shear-lag theory proposed by Cox in 1952 is generalized for fibres with variable radius and with symmetric and asymmetric ends. Analytical solutions are derived for the distribution of axial and interfacial shear stress in cylindrical and elliptical fibres, as well as conical and paraboloidal fibres with asymmetric ends. Additionally, the distribution of axial and interfacial shear stress for conical and paraboloidal fibres with symmetric ends are numerically predicted. The results are compared with solutions from axisymmetric finite element models. A parameter study is performed, to investigate the suitability of alternative fibre geometries for use in FRP.}, language = {en} } @article{BhattaraiHorbachStaatetal.2022, author = {Bhattarai, Aroj and Horbach, Andreas and Staat, Manfred and Kowalczyk, Wojciech and Tran, Thanh Ngoc}, title = {Virgin passive colon biomechanics and a literature review of active contraction constitutive models}, series = {Biomechanics}, volume = {2}, journal = {Biomechanics}, number = {2}, publisher = {MDPI}, address = {Basel}, issn = {2673-7078}, doi = {10.3390/biomechanics2020013}, pages = {138 -- 157}, year = {2022}, abstract = {The objective of this paper is to present our findings on the biomechanical aspects of the virgin passive anisotropic hyperelasticity of the porcine colon based on equibiaxial tensile experiments. Firstly, the characterization of the intestine tissues is discussed for a nearly incompressible hyperelastic fiber-reinforced Holzapfel-Gasser-Ogden constitutive model in virgin passive loading conditions. The stability of the evaluated material parameters is checked for the polyconvexity of the adopted strain energy function using positive eigenvalue constraints of the Hessian matrix with MATLAB. The constitutive material description of the intestine with two collagen fibers in the submucosal and muscular layer each has been implemented in the FORTRAN platform of the commercial finite element software LS-DYNA, and two equibiaxial tensile simulations are presented to validate the results with the optical strain images obtained from the experiments. Furthermore, this paper also reviews the existing models of the active smooth muscle cells, but these models have not been computationally studied here. The review part shows that the constitutive models originally developed for the active contraction of skeletal muscle based on Hill's three-element model, Murphy's four-state cross-bridge chemical kinetic model and Huxley's sliding-filament hypothesis, which are mainly used for arteries, are appropriate for numerical contraction numerical analysis of the large intestine.}, language = {en} } @article{Golland2022, author = {Golland, Alexander}, title = {Aufsicht und Rechtsdurchsetzung bei unzul{\"a}ssigem Einsatz von Cookies \& Co. unter Geltung des TTDSG}, series = {DSB Datenschutz-Berater}, volume = {46}, journal = {DSB Datenschutz-Berater}, number = {1}, publisher = {DFV Mediengruppe}, address = {Frankfurt a.M.}, isbn = {0170-7256}, pages = {14 -- 16}, year = {2022}, language = {de} } @incollection{HoffschmidtAlexopoulosGoettscheetal.2022, author = {Hoffschmidt, Bernhard and Alexopoulos, Spiros and G{\"o}ttsche, Joachim and Sauerborn, Markus and Kaufhold, O.}, title = {High Concentration Solar Collectors}, series = {Comprehensive Renewable Energy (Second Edition) / Volume 3: Solar Thermal Systems: Components and Applications}, booktitle = {Comprehensive Renewable Energy (Second Edition) / Volume 3: Solar Thermal Systems: Components and Applications}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {978-0-12-819734-9}, doi = {10.1016/B978-0-12-819727-1.00058-3}, pages = {198 -- 245}, year = {2022}, abstract = {Solar thermal concentrated power is an emerging technology that provides clean electricity for the growing energy market. To the solar thermal concentrated power plant systems belong the parabolic trough, the Fresnel collector, the solar dish, and the central receiver system. For high-concentration solar collector systems, optical and thermal analysis is essential. There exist a number of measurement techniques and systems for the optical and thermal characterization of the efficiency of solar thermal concentrated systems. For each system, structure, components, and specific characteristics types are described. The chapter presents additionally an outline for the calculation of system performance and operation and maintenance topics. One main focus is set to the models of components and their construction details as well as different types on the market. In the later part of this article, different criteria for the choice of technology are analyzed in detail.}, language = {en} } @article{MarinkovićButenweg2022, author = {Marinković, Marko and Butenweg, Christoph}, title = {Experimental testing of decoupled masonry infills with steel anchors for out-of-plane support under combined in-plane and out-of-plane seismic loading}, series = {Construction and Building Materials}, volume = {318}, journal = {Construction and Building Materials}, number = {1}, editor = {Ford, Michael C.}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1879-0526}, doi = {10.1016/j.conbuildmat.2021.126041}, year = {2022}, abstract = {Because of simple construction process, high energy efficiency, significant fire resistance and excellent sound isolation, masonry infilled reinforced concrete (RC) frame structures are very popular in most of the countries in the world, as well as in seismic active areas. However, many RC frame structures with masonry infills were seriously damaged during earthquake events, as the traditional infills are generally constructed with direct contact to the RC frame which brings undesirable infill/frame interaction. This interaction leads to the activation of the equivalent diagonal strut in the infill panel, due to the RC frame deformation, and combined with seismically induced loads perpendicular to the infill panel often causes total collapses of the masonry infills and heavy damages to the RC frames. This fact was the motivation for developing different approaches for improving the behaviour of masonry infills, where infill isolation (decoupling) from the frame has been more intensively studied in the last decade. In-plane isolation of the infill wall reduces infill activation, but causes the need for additional measures to restrain out-of-plane movements. This can be provided by installing steel anchors, as proposed by some researchers. Within the framework of European research project INSYSME (Innovative Systems for Earthquake Resistant Masonry Enclosures in Reinforced Concrete Buildings) the system based on a use of elastomers for in-plane decoupling and steel anchors for out-of-plane restrain was tested. This constructive solution was tested and deeply investigated during the experimental campaign where traditional and decoupled masonry infilled RC frames with anchors were subjected to separate and combined in-plane ‬and out-of-plane loading. Based on a detailed evaluation and comparison of the test results, the performance and effectiveness of the developed system are illustrated.}, language = {en} } @article{TranTrinhDaoetal.2022, author = {Tran, Ngoc Trinh and Trinh, Tu Luc and Dao, Ngoc Tien and Giap, Van Tan and Truong, Manh Khuyen and Dinh, Thuy Ha and Staat, Manfred}, title = {FEM shakedown analysis of structures under random strength with chance constrained programming}, series = {Vietnam Journal of Mechanics}, volume = {44}, journal = {Vietnam Journal of Mechanics}, number = {4}, publisher = {Vietnam Academy of Science and Technology (VAST)}, issn = {0866-7136}, doi = {10.15625/0866-7136/17943}, pages = {459 -- 473}, year = {2022}, abstract = {Direct methods, comprising limit and shakedown analysis, are a branch of computational mechanics. They play a significant role in mechanical and civil engineering design. The concept of direct methods aims to determine the ultimate load carrying capacity of structures beyond the elastic range. In practical problems, the direct methods lead to nonlinear convex optimization problems with a large number of variables and constraints. If strength and loading are random quantities, the shakedown analysis can be formulated as stochastic programming problem. In this paper, a method called chance constrained programming is presented, which is an effective method of stochastic programming to solve shakedown analysis problems under random conditions of strength. In this study, the loading is deterministic, and the strength is a normally or lognormally distributed variable.}, language = {en} } @incollection{HebelHerrmannRitzetal.2022, author = {Hebel, Christoph and Herrmann, Ulf and Ritz, Thomas and R{\"o}th, Thilo and Anthrakidis, Anette and B{\"o}ker, J{\"o}rg and Franzke, Till and Grodzki, Thomas and Merkens, Torsten and Sch{\"o}ttler, Mirjam}, title = {FlexSHARE - Methodisches Framework zur innovativen Gestaltung der urbanen Mobilit{\"a}t durch Sharing- Angebote}, series = {Transforming Mobility - What Next?}, booktitle = {Transforming Mobility - What Next?}, publisher = {Springer Gabler}, address = {Wiesbaden}, isbn = {978-3-658-36429-8}, doi = {10.1007/978-3-658-36430-4_10}, pages = {153 -- 169}, year = {2022}, abstract = {Das Ziel des INTERREG-Projektes „SHAREuregio" (FKZ: 34.EFRE-0300134) ist es, grenz{\"u}berschreitende Mobilit{\"a}t in der Euregio Rhein-Maas-Nord zu erm{\"o}glichen und zu f{\"o}rdern. Dazu soll ein elektromobiles Car- und Bikesharing- System entwickelt und in der Stadt M{\"o}nchengladbach, im Kreis Viersen sowie in den Gemeinden Roermond und Venlo (beide NL) zusammen mit den Partnern Wirtschaftsf{\"o}rderung M{\"o}nchengladbach, Wirtschaftsf{\"o}rderung f{\"u}r den Kreis Viersen, NEW AG, Goodmoovs (NL), Greenflux (NL) und der FH Aachen implementiert werden. Zun{\"a}chst richtet sich das Angebot, bestehend aus 40 Elektroautos und 40 Elektrofahrr{\"a}dern, an Unternehmen und wird nach einer Erprobungsphase, mit einer gr{\"o}ßeren Anzahl an Fahrzeugen, auch f{\"u}r Privatpersonen verf{\"u}gbar gemacht werden. Die Fahrzeuge stehen bei den jeweiligen Anwendungspartnern in Deutschland und den Niederlanden. Im Rahmen dieses Projektes hat die FH Aachen „FlexSHARE" entwickelt - ein methodisches Framework zur innovativen Gestaltung urbaner Sharing- Angebote. Das Framework erm{\"o}glicht es, anhand von messbaren Kenngr{\"o}ßen, bedarfsgerechte und auf die Region abgestimmte Sharing-Systeme zu entwickeln.}, language = {de} } @inproceedings{WeldenSeverinsPoghossianetal.2022, author = {Welden, Melanie and Severins, Robin and Poghossian, Arshak and Wege, Christina and Siegert, Petra and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Studying the immobilization of acetoin reductase with Tobacco mosaic virus particles on capacitive field-effect sensors}, series = {2022 IEEE International Symposium on Olfaction and Electronic Nose (ISOEN)}, booktitle = {2022 IEEE International Symposium on Olfaction and Electronic Nose (ISOEN)}, publisher = {IEEE}, isbn = {978-1-6654-5860-3 (Online)}, doi = {10.1109/ISOEN54820.2022.9789657}, pages = {4 Seiten}, year = {2022}, abstract = {A capacitive electrolyte-insulator-semiconductor (EISCAP) biosensor modified with Tobacco mosaic virus (TMV) particles for the detection of acetoin is presented. The enzyme acetoin reductase (AR) was immobilized on the surface of the EISCAP using TMV particles as nanoscaffolds. The study focused on the optimization of the TMV-assisted AR immobilization on the Ta 2 O 5 -gate EISCAP surface. The TMV-assisted acetoin EISCAPs were electrochemically characterized by means of leakage-current, capacitance-voltage, and constant-capacitance measurements. The TMV-modified transducer surface was studied via scanning electron microscopy.}, language = {en} } @masterthesis{Wojcieszak2022, type = {Bachelor Thesis}, author = {Wojcieszak, Marc David}, title = {Da Capo - The Town of Music}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {43 Seiten}, year = {2022}, abstract = {In dem Film geht es um die Musikstadt "Da Capo", in der jedes Genre sein eigenes Viertel hat. Unser Protagonist wurde im falschen Viertel geboren und muss sich nun heraus musizieren.}, language = {de} } @masterthesis{Wick2022, type = {Bachelor Thesis}, author = {Wick, Dorian}, title = {bulk : Konzeption und Gestaltung einer mobilen Anwendung eines nachhaltigen Unverpackt-Lieferservice}, publisher = {FH Aachen}, address = {Aachen}, pages = {171 Seiten}, year = {2022}, abstract = {Die Welt wird wortw{\"o}rtlich von Plastik {\"u}berschwemmt- und trotzdem ist kein Ende des trivialen Verpackungsmaterials in Sicht. Die, die sich den Konsequenzen ihres Konsumverhaltens bewusst sind, haben immer noch keinen fl{\"a}chendeckenden Zugang zu Unverpacktl{\"a}den und es mangelt schlicht an praktischen Alternativen. Hier kn{\"u}pft die App „bulk" an und schl{\"a}gt ausschließlich unverpackte Lebensmittel vor - bequem bis zur Haust{\"u}r geliefert. Das Angebot ist qualitativ hochwertig und meist regional. F{\"u}r ein positives Kauferlebnis veranschaulicht „bulk", wie viel Plastik mit den Produkten im Vergleich zu einem konventionellen Wocheneinkauf eingespart werden kann. Das gibt Nutzer:Innen eine Grundlage, ihre Entscheidungen kritisch zu hinterfragen und schult den Blick f{\"u}r den Impact sich summierender Kleinigkeiten.}, language = {de} } @masterthesis{Eberhardt2022, type = {Bachelor Thesis}, author = {Eberhardt, Dag Norman}, title = {"I Was Here!"}, publisher = {FH Aachen}, address = {Aachen}, pages = {77 Seiten}, year = {2022}, abstract = {Die Menschheit erlebt aktuell Zeiten drastischen Wandels. Deswegen k{\"o}nnte es wohltun, einen Blick in die Vergangenheit zu werfen und sich darauf zu besinnen, wo die Menschen herkommen, wer sie waren und was seitdem bereits erreicht wurde. In dieser Grafiknovelle wird ein kleiner Steinzeitjunge namens Muami begleitet, der vor 35.000 Jahren die Verg{\"a}nglichkeit des Lebens kennenlernt. Im Verlauf des folgenden Jahres erfindet er die Selbstverewigung in der H{\"o}hlenmalerei. Mit seiner Figur soll aufgezeigt werden, dass die fr{\"u}hen Europ{\"a}er eben keine primitiven Halbaffen, sondern intelligente und außerdem zutiefst kreative Menschen waren. Trotz ihrer rauen Umwelt waren ihre Sorgen und Freuden den unseren gar nicht so un{\"a}hnlich. „I Was Here!" ist ein Versuch, ein authentisches Portr{\"a}t jener Menschen zu schaffen und dabei ihrer Welt, ihrem Leben und ihrer Kunst gerecht zu werden.}, language = {de} } @masterthesis{Wolters2022, type = {Bachelor Thesis}, author = {Wolters, Marina}, title = {Zeitfenster : Prototyp einer animierten Installation zum Thema Mesokosmos und Lebensraum Erde}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {171 Seiten}, year = {2022}, abstract = {Der Prototyp des Projekts "Zeitfenster" stellt eine Installation dar, inspiriert vom Museum f{\"u}r Naturkunde Berlin. Die Installation besteht aus einer Animation, die an die Fenster des Dinosauriersaals im Museum pojiziert wird. Die Animation zeigt in einer Art Zeitreise, wie das Erbe der Natur aussieht und was der Mensch daraus macht. In der Zeit des Klimawandels setzt sich Design vermehrt f{\"u}r die Aufkl{\"a}rung des Naturschutzes ein. Die Animation soll die Zuschauer, ob Jung oder Alt, f{\"u}r die Verbindung zwischen dem Menschen und der Erde sensibilisieren. Dies wird erreicht, indem sich die Installation die atemberaubende Atmosph{\"a}re des Dinosauriersaals zu Nutze macht. Die Fenster des Saals erlauben es, die Bildnisse in beeindruckender Lebensgr{\"o}ße darzustellen. Im Fokus steht, dass der Prototyp ein Erlebnis konzipiert, welches nur durch das Zusammenspiel der verschiedenen Medien m{\"o}glich ist.}, language = {de} } @masterthesis{Switalla2022, type = {Bachelor Thesis}, author = {Switalla, Justin}, title = {Applause : Entwicklung eines Dokumentationssystems f{\"u}r die station{\"a}re Altenpflege - Konzeption einer zukunftsgewandten Dokumentationsl{\"o}sung}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {213 Seiten}, year = {2022}, abstract = {Der Personalmangel in der Pflege ist vor allem durch die Pandemie in den Fokus der {\"O}ffentlichkeit ger{\"u}ckt. Diese Situation wird sich in den n{\"a}chsten Jahren aufgrund der steigenden Pflegequote in Folge des demografischen Wandels weiter zuspitzen. Das Dokumentieren der durchgef{\"u}hrten T{\"a}tigkeiten nimmt dabei viel Zeit in Anspruch, die nicht den Bewohner:innen zugutekommt. Das Dokumentationssystem „Applause" soll Pflege- und Betreuungskr{\"a}fte in ihrer Arbeit unterst{\"u}tzen und durch die einfache Nutzerf{\"u}hrung den Schulungsaufwand reduzieren. Durch die Integration von modernen medizinischen Sensoren kann innerhalb des Systems der aktuelle Gesundheitsstatus der Bewohner:innen eingesehen werden. Zus{\"a}tzlich wird die interne sowie externe Kommunikation innerhalb des Dokumentationssystems abgebildet. Bei Letzterer wird mittels einer datenschutzkonformen Software die auf Fax basierende Kommunikation abgel{\"o}st.}, language = {de} } @article{MolinnusIkenJohnenetal.2022, author = {Molinnus, Denise and Iken, Heiko and Johnen, Anna Lynn and Richstein, Benjamin and Hellmich, Lena and Poghossian, Arshak and Knoch, Joachim and Sch{\"o}ning, Michael Josef}, title = {Miniaturized pH-Sensitive Field-Effect Capacitors with Ultrathin Ta₂O₅ Films Prepared by Atomic Layer Deposition}, series = {physica status solidi (a) applications and materials science}, volume = {219}, journal = {physica status solidi (a) applications and materials science}, number = {8}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.202100660}, pages = {7 Seiten}, year = {2022}, abstract = {Miniaturized electrolyte-insulator-semiconductor capacitors (EISCAPs) with ultrathin gate insulators have been studied in terms of their pH-sensitive sensor characteristics: three different EISCAP systems consisting of Al-p-Si-Ta2O5(5 nm), Al-p-Si-Si3N4(1 or 2 nm)-Ta2O5 (5 nm), and Al-p-Si-SiO2(3.6 nm)-Ta2O5(5 nm) layer structures are characterized in buffer solution with different pH values by means of capacitance-voltage and constant capacitance method. The SiO2 and Si3N4 gate insulators are deposited by rapid thermal oxidation and rapid thermal nitridation, respectively, whereas the Ta2O5 film is prepared by atomic layer deposition. All EISCAP systems have a clear pH response, favoring the stacked gate insulators SiO2-Ta2O5 when considering the overall sensor characteristics, while the Si3N4(1 nm)-Ta2O5 stack delivers the largest accumulation capacitance (due to the lower equivalent oxide thickness) and a higher steepness in the slope of the capacitance-voltage curve among the studied stacked gate insulator systems.}, language = {en} } @misc{Leontieva2022, type = {Master Thesis}, author = {Leontieva, Ksenia Andreevna}, title = {Die Facetten Hamburgs}, publisher = {FH Aachen}, address = {Aachen}, pages = {137 Seiten}, year = {2022}, abstract = {Im Rahmen dieser Masterarbeit entsteht ein neues Erscheinungsbild f{\"u}r die "Stiftung Historische Museen Hamburg". Dabei wurde ein medien{\"u}bergreifendes Gestaltungskonzept entwickelt, welches dazu dienen soll, die Stiftung und deren musealen Einrichtungen modern, aussagekr{\"a}ftig und repr{\"a}sentativ neu aufleben zu lassen, als auch das Interesse unserer Gesellschaft f{\"u}r Kunst, Kultur und Geschichte zu wecken und damit die Zielgruppe zu erweitern. Hierzu wurde das Corporate Design neu entwickelt, minimalisiert und modernisiert. Durch den aufger{\"a}umten und organisierten digitalen Auftritt gelangen Interessenten schneller und gezielter zu Informationen {\"u}ber die Stiftung, die einzelnen Museen und deren Programm und Ausstellungen. Zus{\"a}tzlich dienen als weiterf{\"u}hrende Informationsquellen neu getslatete analoge Medien in Form von Plakaten, Flyern, Brosch{\"u}ren und Eintrittskarten. Weitestgehend wurde das Corporate Design in den urbanen Lebensraum der Stadt Hamburg integriert und neu interpretiert. Aus dem Gestaltungskonzept l{\"a}sst sich ebenfalls ein neues Leitsystem zur besseren Orientierung in den Museen ableiten. Das Designkonzept zieht sich wie ein roter Faden durch alle Medien, um eine Einheit und einen Wiedererkennungswert zu schaffen und seri{\"o}s und informativ zu wirken. Das Projekt ist rein fiktiv.}, language = {de} } @masterthesis{Krebs2022, type = {Bachelor Thesis}, author = {Krebs, Benedikt}, title = {Das Online-Ich : Erlebnis-Installation zur Reflexion {\"u}ber das digitale Selbst}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {38 Seiten}, year = {2022}, abstract = {Soziale Netzwerke geh{\"o}ren zu den gr{\"o}ßten Konzernen der Welt. Hier werden min{\"u}tlich Millionen von Nachrichten verschickt. Das Internet spielt eine stetig wachsende Rolle in der zwischenmenschlichen Kommunikation. Und doch funktioniert dort nicht nur die Sprache anders, auch die Pers{\"o}nlichkeit der Menschen kann sich auch ver{\"a}ndern. Diese Arbeit besch{\"a}ftigt sich mit dem „Online-Ich", das jeder in sich tragen soll. H{\"a}ufig ist dieses offener, hilfsbereiter und selbstloser, aber eben auch reizbarer, aggressiver und energetischer. Um auf diese Ver{\"a}nderung aufmerksam zu machen, werden die analoge und digitale Pers{\"o}nlichkeit verglichen. Dazu sch{\"o}pft die Arbeit aus den vielf{\"a}ltigen M{\"o}glichkeiten von Virtual Reality, um Betrachtende in die Arbeit miteinzubeziehen.}, language = {de} } @article{HeuermannEmmrichBongartz2022, author = {Heuermann, Holger and Emmrich, Thomas and Bongartz, Simon}, title = {Microwave spark plug to support ignitions with high compression ratios}, series = {IEEE Transactions on Plasma Science}, journal = {IEEE Transactions on Plasma Science}, number = {Early Access}, publisher = {IEEE}, issn = {1939-9375}, doi = {10.1109/TPS.2022.3183690}, pages = {1 -- 6}, year = {2022}, abstract = {Upcoming gasoline engines should run with a larger number of fuels beginning from petrol over methanol up to gas by a wide range of compression ratios and a homogeneous charge. In this article, the microwave (MW) spark plug, based on a high-speed frequency hopping system, is introduced as a solution, which can support a nitrogen compression ratio up to 1:39 in a chamber and more. First, an overview of the high-speed frequency hopping MW ignition and operation system as well as the large number of applications are presented. Both gives an understanding of this new base technology for MW plasma generation. Focus of the theoretical part is the explanation of the internal construction of the spark plug, on the achievable of the high voltage generation as well as the high efficiency to hold the plasma. In detail, the development process starting with circuit simulations and ending with the numerical multiphysics field simulations is described. The concept is evaluated with a reference prototype covering the frequency range between 2.40 and 2.48 GHz and working over a large power range from 20 to 200 W. A larger number of different measurements starting by vector hot-S11 measurements and ending by combined working scenarios out of hot temperature, high pressure and charge motion are winding up the article. The limits for the successful pressure tests were given by the pressure chamber. Pressures ranged from 1 to 39 bar and charge motion up to 25 m/s as well as temperatures from 30◦ to 125◦.}, language = {en} } @masterthesis{Traut2022, type = {Bachelor Thesis}, author = {Traut, Eva Melina}, title = {Vom {\"O}ko-Dino zur Lifestyle-Marke : Rebranding f{\"u}r die Bio-Lebensmittelmarke Alnatura}, publisher = {FH Aachen}, address = {Aachen}, pages = {49 Seiten}, year = {2022}, abstract = {Das Thema „Bio" ist auf dem Markt l{\"a}ngst zu einem Mainstream geworden und vor allem bei j{\"u}ngeren Zielgruppen sehr gefragt. Umso wichtiger ist es f{\"u}r Bio-Marken wie ALNATURA, sich zu definieren, um neben innovativen, nachhaltigen Start-up-Marken noch aufzufallen. Aktuell ist ALNATURA vorwiegend aufgrund der hochwertigen Produkte sowie einer transparenten Kommunikation bekannt. Jedoch fehlt es den Produkten an einheitlichem Design mit Wiedererkennungswert. Diese Arbeit zeigt einen Ansatz f{\"u}r ein neues, zeitgem{\"a}ßes Gestaltungskonzept. Im Zuge dessen wurde das Unternehmenslogo modifiziert sowie Farben, Schrift und Gestaltungsraster neu definiert. Um das neue Image der Marke bekannt zu machen, wurde zudem eine Plakatkampagne entwickelt. Das Projekt zeigt, wie sich eine Bio-Marke weg vom {\"O}ko-Image und hin zu einer modernen Lifestyle-Marke mit Relevanz entwickeln kann.}, language = {de} } @masterthesis{Lebrecht2022, type = {Bachelor Thesis}, author = {Lebrecht, Rike-Charlotte}, title = {Inga : ein modulares hydroponisches System f{\"u}r Endverbraucher}, publisher = {FH Aachen}, address = {Aachen}, year = {2022}, abstract = {In dieser Arbeit wurde sich mit der Frage auseinandergesetzt, wie sich der Nahrungsmittelanbau im urbanen Raum entwickeln k{\"o}nnte. Eine spannende Alternative zu traditionellen Anbaumethoden ist die Hydroponik, der Anbau von Pflanzen ohne Erde. Basierend auf dieser Technologie wurde in diesem Projekt ein Indoor-Garden-System gestaltet, welches den Nahrungsmittelanbau zur{\"u}ck zur Verbraucher:In bringt und zu einem bewussteren Umgang mit Lebensmitteln anregen soll. Denn mit „INGA" kann frisches, pestizidfreies Blattgem{\"u}se ganz einfach zu Hause selbst angebaut werden. Das hydroponische System schafft mithilfe einer N{\"a}hrstoffl{\"o}sung und k{\"u}nstlichem Licht optimale Wachstumsbedingungen f{\"u}r die Pflanzen - ganz unabh{\"a}ngig von {\"o}rtlichen Gegebenheiten. Mithilfe seiner Modularit{\"a}t k{\"o}nnen Nutzer:Innen „INGA" nach Belieben konfigurieren. Damit wird es einer breiten Zielgruppe mit unterschiedlichen Bed{\"u}rfnissen gerecht und erm{\"o}glicht pestizidfreie Nahrung - auch in den St{\"a}dten.}, language = {de} } @masterthesis{Lesmeister2022, type = {Bachelor Thesis}, author = {Lesmeister, David}, title = {VIUR : urbanes Lagerfeuer}, publisher = {FH Aachen}, address = {Aachen}, pages = {131 Seiten}, year = {2022}, abstract = {Es kann ganze Lebensr{\"a}ume ausl{\"o}schen, und doch w{\"a}re unsere Welt nicht die gleiche ohne Feuer. Feuer spielt eine wichtige Rolle in der menschlichen Evolution und diente unseren Vorfahren zum Schutz vor wilden Tieren, Kochen und zum W{\"a}rmen. Auch Gespr{\"a}che am Lagerfeuer sollen einen erheblichen Einfluss auf die soziale und kulturelle Evolution des Menschen gehabt haben. Kein Wunder also, dass die Menschen bis heute mit Feuer ein Gef{\"u}hl von Gemeinschaft und Geborgenheit verbinden. Genau diese Wirkung greift „VIUR" auf und macht Feuer alltagstauglich f{\"u}r eine Welt, die von Urbanisierung und Digitalisierung gepr{\"a}gt ist. Entstanden ist ein Hybrid aus einem Tischfeuer und einem Grill. Somit entsteht sowohl das sinnliche Erlebnis einer Feuerstelle als auch die M{\"o}glichkeit, kleine Speisen zuzubereiten. Die smarte Konstruktion und ein Sicherheitsbrennstoff, mit dem sich kaum Rauch entwickeln kann, erm{\"o}glicht die Nutzung im kleinen Garten, aber eben auch auf einem Stadtbalkon. So kann das Lagerfeuer wieder seinen Zauber entfalten.}, language = {de} } @masterthesis{NiggeMans2022, type = {Bachelor Thesis}, author = {Nigge-Mans, Leonard}, title = {Entwicklung einer Arbeitsplatzleuchte}, publisher = {FH Aachen}, address = {Aachen}, pages = {74 Seiten}, year = {2022}, abstract = {F{\"u}r manche mag es banal wirken, doch f{\"u}r Gestalter:innen ist sie unverzichtbar: eine wirklich gute Leuchte f{\"u}r den Arbeitsplatz. Sie hat n{\"a}mlich einen enormen Einfluss auf die Konzentration und den Komfort. Zudem erm{\"o}glicht gutes Licht erst ein sauberes und farbechtes Ergebnis. Daf{\"u}r wurde in diesem Projekt die perfekte Leuchte entwickelt. Sie leuchtet die Arbeitsfl{\"a}che ideal aus und unterst{\"u}tzt das Lesen, Schreiben oder die Arbeit mit technischen Ger{\"a}ten. Durch f{\"u}nf Drehpunkte ist die Leuchte in alle Richtungen zu bewegen und l{\"a}sst sich somit individuell auf ihre Aufgaben anpassen. Außerdem wurde Wert daraufgelegt, bestehende Normen und Vorschiften einzuhalten, um den Arbeit- und Gesundheitsschutz zu gew{\"a}hrleisten. Feierabend? Durch die Dim-Funktion wird die Arbeitsleuchte zu einer gem{\"u}tlichen Lichtquelle. Unter anderem durch die unsichtbare Stromf{\"u}hrung {\"u}berzeugt die Lampe mit ihrer minimalistischen Designsprache und l{\"a}sst sich in unterschiedlichste R{\"a}ume integrieren.}, language = {de} } @masterthesis{Geilhausen2022, type = {Bachelor Thesis}, author = {Geilhausen, Ayleen}, title = {SUE : Restauranterlebnisse neu gestalten}, publisher = {FH Aachen}, address = {Aachen}, pages = {121 Seiten}, year = {2022}, abstract = {Gastronomiebetriebe, insbesondere diese ohne zeitgem{\"a}ße und durchdachte Konzepte wurden durch die Pandemie stark getroffen. W{\"a}hrend große Fast-Food-Ketten bereits vor der Pandemie digitale L{\"o}sungen einsetzten, stehen nun auch andere Restaurantbetreiber:innen vor der Herausforderung der Digitalisierung. Gerade die Pandemie hat an dieser Stelle verdeutlicht, welche Restaurants ihre Prozesse im Sinne der User Experience durchdacht haben und welche nicht. Die Tisch-Stuhl-Kombination der „SUE"-Serie bietet Restaurants, smarte und elegante Gastronomiem{\"o}bel, die je nach Konzept in Materialit{\"a}t und Farbe frei anpassbar sind. Wandelbarkeit, Komfort und die Integration digitaler L{\"o}sungen sind die Kernkompetenzen und Anforderungen, die das Gastronomie-Interior in Zukunft erf{\"u}llen muss. Der smarte Bistrotisch und der wandelbare Stuhl der „SUE"-Serie zeigt einen digitalisierten und anpassbaren L{\"o}sungsansatz.}, language = {de} } @masterthesis{Braun2022, type = {Bachelor Thesis}, author = {Braun, Linus}, title = {Faces - Lebenswerte Mobilit{\"a}t in St{\"a}dten}, publisher = {FH Aachen}, address = {Aachen}, pages = {173 Seiten}, year = {2022}, abstract = {Mobilit{\"a}t stellt oftmals ein Problem in St{\"a}dten dar. Es sind Staus, Abgase, Platzmangel, die sich negativ auf die urbane Lebensqualit{\"a}t auswirken. Dies sind externe Auswirkungen der von Autos dominierten Mobilit{\"a}t. Ziel von „Faces" war es, eine effiziente und vor allem attraktive Alternative zum Automobil zu bieten. Daf{\"u}r denkt das Projekt die Straßenbahn neu. Durch kompaktes Design und die Verwendung autonomer Systeme wird eine h{\"o}here Taktung erm{\"o}glicht. Zudem werden die Bahnen flexibler und k{\"o}nnen den Einsatz am Mobilit{\"a}tsbedarf anpassen. Um den Bed{\"u}rfnissen der Fahrg{\"a}ste gerecht zu werden, l{\"a}sst sich das modulare Interior an die Reisedistanz anpassen. Hier wird ein Mobilit{\"a}tskonzept gezeichnet, das einem mit einem hoffnungsvollen Blick auf das Leben in den St{\"a}dten der Zukunft zur{\"u}ckl{\"a}sst.}, language = {de} } @masterthesis{Bortmann2022, type = {Bachelor Thesis}, author = {Bortmann, Alevtina}, title = {Produktion eines „Corporate Identity"- Werbefilms f{\"u}r ein IoT Technologieunternehmen}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {45 Seiten}, year = {2022}, abstract = {Mit einem Werbefilm kann man seine Zielgruppe schnell und einfach in wenigen Minuten erreichen, indem man sich als Unternehmen auf eine freundliche Art und Weise vorstellt und somit Vertrauen und Kontakt zu der Zielgruppe herstellt. Außerdem bietet ein Werbefilm eine gute M{\"o}glichkeit sein Unternehmen als modernes und leistungsstarkes Unternehmen zu pr{\"a}sentieren, um potenzielle Kunden oder sogar neue Mitarbeiter zu werben. Mit einem {\"u}berzeugendem Werbefilm, der richtigen Musik und Animation, bleibt ein Werbefilm im Ged{\"a}chtnis der Zuschauer, viel besser als es Printwerbung in Form von einem Flyer oder einer Brosch{\"u}re erf{\"u}llen kann. Zus{\"a}tzlich kann man seine Reichweite im Social-Media Bereich um weitere Kan{\"a}le erweitern. Dies wiederum erm{\"o}glicht dem Unternehmen seinen Kundenstamm zu st{\"a}rken und auszubauen.}, language = {de} } @masterthesis{Voth2022, type = {Bachelor Thesis}, author = {Voth, Emily}, title = {KiWA : Die Garderobe f{\"u}r kleine Selbstst{\"a}ndige}, publisher = {FH Aachen}, address = {Aachen}, pages = {117 Seiten}, year = {2022}, abstract = {Kindertagesst{\"a}tten bieten Kleinkindern den Zugang zu unbeschwertem und spielerischem Lernen. Was also, wenn schon der Eingangsbereich die Reiz{\"u}berflutung bereit h{\"a}lt, der Stauraum der Entfaltung der Kinder nicht gerecht wird und ihre Eigenst{\"a}ndigkeit ungef{\"o}rdert bleibt? Es kommt zu unzufriedenen Kindern und Frustration aller Beteilligten. "KIWA" ist das Garderobensystem f{\"u}r Kinder zur St{\"a}rkung der heranwachsenden Selbstst{\"a}ndigkeit. Mithilfe von pers{\"o}nlichen Wiedererkennungsmerkmalen wird Eigenverantwortung geschult. Leicht und sicher zu erreichender Stauraum sorgt f{\"u}r Ordnung. Spielerisches lernen trotz Ordnung.}, language = {de} } @article{MonakhovaDiehl2022, author = {Monakhova, Yulia and Diehl, Bernd W.K.}, title = {Multinuclear NMR screening of pharmaceuticals using standardization by 2H integral of a deuterated solvent}, series = {Journal of Pharmaceutical and Biomedical Analysis}, volume = {209}, journal = {Journal of Pharmaceutical and Biomedical Analysis}, number = {Article number: 114530}, publisher = {Elsevier}, isbn = {0731-7085}, doi = {10.1016/j.jpba.2021.114530}, year = {2022}, abstract = {NMR standardization approach that uses the 2H integral of deuterated solvent for quantitative multinuclear analysis of pharmaceuticals is described. As a proof of principle, the existing NMR procedure for the analysis of heparin products according to US Pharmacopeia monograph is extended to the determination of Na+ and Cl- content in this matrix. Quantification is performed based on the ratio of a 23Na (35Cl) NMR integral and 2H NMR signal of deuterated solvent, D2O, acquired using the specific spectrometer hardware. As an alternative, the possibility of 133Cs standardization using the addition of Cs2CO3 stock solution is shown. Validation characteristics (linearity, repeatability, sensitivity) are evaluated. A holistic NMR profiling of heparin products can now also be used for the quantitative determination of inorganic compounds in a single analytical run using a single sample. In general, the new standardization methodology provides an appealing alternative for the NMR screening of inorganic and organic components in pharmaceutical products.}, language = {en} } @article{MolinnusJanusFangetal.2022, author = {Molinnus, Denise and Janus, Kevin Alexander and Fang, Anyelina C. and Drinic, Aleksander and Achtsnicht, Stefan and K{\"o}pf, Marius and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Thick-film carbon electrode deposited onto a biodegradable fibroin substrate for biosensing applications}, series = {Physica status solidi (a)}, volume = {219}, journal = {Physica status solidi (a)}, number = {23}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.202200100}, pages = {1 -- 9}, year = {2022}, abstract = {This study addresses a proof-of-concept experiment with a biocompatible screen-printed carbon electrode deposited onto a biocompatible and biodegradable substrate, which is made of fibroin, a protein derived from silk of the Bombyx mori silkworm. To demonstrate the sensor performance, the carbon electrode is functionalized as a glucose biosensor with the enzyme glucose oxidase and encapsulated with a silicone rubber to ensure biocompatibility of the contact wires. The carbon electrode is fabricated by means of thick-film technology including a curing step to solidify the carbon paste. The influence of the curing temperature and curing time on the electrode morphology is analyzed via scanning electron microscopy. The electrochemical characterization of the glucose biosensor is performed by amperometric/voltammetric measurements of different glucose concentrations in phosphate buffer. Herein, systematic studies at applied potentials from 500 to 1200 mV to the carbon working electrode (vs the Ag/AgCl reference electrode) allow to determine the optimal working potential. Additionally, the influence of the curing parameters on the glucose sensitivity is examined over a time period of up to 361 days. The sensor shows a negligible cross-sensitivity toward ascorbic acid, noradrenaline, and adrenaline. The developed biocompatible biosensor is highly promising for future in vivo and epidermal applications.}, language = {en} } @article{EngelmannPourshahidiShalabyetal.2022, author = {Engelmann, Ulrich M. and Pourshahidi, Mohammad Ali and Shalaby, Ahmed and Krause, Hans-Joachim}, title = {Probing particle size dependency of frequency mixing magnetic detection with dynamic relaxation simulation}, series = {Journal of Magnetism and Magnetic Materials}, volume = {563}, journal = {Journal of Magnetism and Magnetic Materials}, number = {In progress, Art. No. 169965}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0304-8853}, doi = {10.1016/j.jmmm.2022.169965}, year = {2022}, abstract = {Biomedical applications of magnetic nanoparticles (MNP) fundamentally rely on the particles' magnetic relaxation as a response to an alternating magnetic field. The magnetic relaxation complexly depends on the interplay of MNP magnetic and physical properties with the applied field parameters. It is commonly accepted that particle core size is a major contributor to signal generation in all the above applications, however, most MNP samples comprise broad distribution spanning nm and more. Therefore, precise knowledge of the exact contribution of individual core sizes to signal generation is desired for optimal MNP design generally for each application. Specifically, we present a magnetic relaxation simulation-driven analysis of experimental frequency mixing magnetic detection (FMMD) for biosensing to quantify the contributions of individual core size fractions towards signal generation. Applying our method to two different experimental MNP systems, we found the most dominant contributions from approx. 20 nm sized particles in the two independent MNP systems. Additional comparison between freely suspended and immobilized MNP also reveals insight in the MNP microstructure, allowing to use FMMD for MNP characterization, as well as to further fine-tune its applicability in biosensing.}, language = {en} } @misc{Buechel2022, type = {Master Thesis}, author = {B{\"u}chel, Carolin}, title = {GYMLET : dein mobiles Freiluftstudio - Entwicklung eines serientauglichen Prototypen und einer Vermarktungsstrategie}, publisher = {FH Aachen}, address = {Aachen}, pages = {93 Seiten}, year = {2022}, abstract = {Sportvereine verlieren zunehmend Mitglieder. Grund daf{\"u}r ist der wachsende Wunsch nach unabh{\"a}ngigen Trainingsm{\"o}glichkeiten. GYMLET bietet den Sportler:innen die M{\"o}glichkeit, ihre Fitness funktional, selbstorganisiert und unabh{\"a}ngig zu trainieren. Dabei kann durch den selbstbestimmten Trainingsort neben der k{\"o}rperlichen Fitness vor allem die Motivation zur sportlichen Aktivit{\"a}t und das Wohlbefinden gesteigert werden. Unterst{\"u}tzt wird das Trainingssystem durch eine App, welche den Sportler:innen neben Nutzungsm{\"o}glichkeiten als Coach und Trainingsplaner dient. Um diese Trainingsm{\"o}glichkeit an die Zielgruppe heranzutragen, ist eine Kampagnenstrategie aus zwei Phasen entstanden. In dieser sollen Postings und Clips {\"u}ber Instagram und Youtube ver{\"o}ffentlicht werden. Zus{\"a}tzlich werden Zeitschriften und m{\"o}gliche Kooperationen mit Therapeuten oder Freizeitunterk{\"u}nften zur Ver{\"o}ffentlichung der Kampagne genutzt.}, language = {de} } @masterthesis{Victoria2022, type = {Bachelor Thesis}, author = {Victoria, Jacqueline}, title = {IN BETWEEN : An attempt to capture emotions}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {83 Seiten}, year = {2022}, abstract = {Emotionen durchlebt jeder Mensch. Von unserer Geburt bis zu unserem Tod. Der Psychologe Paul Eckman hat sechs grundlegende Emotionen identifiziert. Gl{\"u}ck, Traurigkeit, Ekel, Angst, {\"U}berraschung und Wut. Emotionen k{\"o}nnen in positive und negative, aber auch in die weniger beachtete neutrale Emotion unterteilt werden. Emotionen werden st{\"a}ndig und wechselnd erlebt und sind deshalb vorstellbar als "Spektrum" oder als "Unendlichkeitschleife". Wie Menschen Emotionen erfahren, ist unterschiedlich. Sie sind abstrakt. Das Fotobuch "In Between" will das Emotionsspektrum und das Abstrakte mithilfe einer Kurzgeschichte sichtbar machen. Das Editorial und die fotografische Gestaltung greifen das Konzept der endlosen Schleife unserer Gef{\"u}hlswelt auf und machen sie erlebbar.}, language = {de} } @masterthesis{Frank2022, type = {Bachelor Thesis}, author = {Frank, Jemima Leonie}, title = {Falling in love with the female gaze}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {81 Seiten}, year = {2022}, abstract = {Der „Male Gaze" bezeichnet das typische Erleben der Umwelt aus m{\"a}nnlicher Perspektive und pr{\"a}gt in den sogenannten Mainstream-Medien die Gestaltung von Film, Fernsehen und Werbung. Dadurch werden von dargestellten Personen h{\"a}ufig die k{\"o}rperlichen Aspekte hervorgehoben. Im Gegensatz dazu gilt das weibliche Pendant, der „Female Gaze", als besonders emotionsbetont. Weil Medien einen enormen Einfluss auf gesellschaftliches und individuelles Denken haben, stellt die Dominanz des „Male Gaze" eine Unausgeglichenheit dar, die sich in verschiedenen Bereichen des gesellschaftlichen Lebens widerspiegelt. Deswegen m{\"o}chte dieses Projekt die Medien um die weibliche Sichtweise erweitern und damit die dort transportierten Bilder diverser und ausgewogener machen. Die Fotografie fokussiert sich dabei auf die Gef{\"u}hlswelt der Protagonistin, womit die Betrachter:Innen schrittweise in ihre Position hineinversetzt werden sollen. Mit Augen des Mitgef{\"u}hls und eigenem Sch{\"o}nheitsbegriff l{\"a}sst „Falling in love with the female gaze" endlich auch die Frau zu Wort kommen.}, language = {de} }