@incollection{FinkenbergerBaumeisterKoch2019,
  author    = {Finkenberger, Isabel Maria and Baumeister, Eva-Maria and Koch, Christian},
  title     = {Komplement und Verst{\"a}rker : der Diskurs geht weiter},
  series = {Komplement und Verst{\"a}rker : zum Verh{\"a}ltnis von Stadtplanung, k{\"u}nstlerischen Praktiken und Kulturinstitutionen},
  booktitle = {Komplement und Verst{\"a}rker : zum Verh{\"a}ltnis von Stadtplanung, k{\"u}nstlerischen Praktiken und Kulturinstitutionen},
  publisher = {JOVIS Verlag},
  address   = {Berlin},
  isbn      = {978-3-86859-578-9},
  pages     = {40 -- 49},
  year      = {2019},
  language  = {de}
}
@article{Fabo2022,
  author    = {Fabo, Sabine},
  title     = {Das Parasit{\"a}re in der Pandemie},
  series = {Parasite Art},
  journal   = {Parasite Art},
  number    = {Issue 2},
  editor    = {Wirth, Jacob},
  publisher = {Parasite Art},
  pages     = {8 -- 11},
  year      = {2022},
  language  = {de}
}
@incollection{Kurz2021,
  author    = {Kurz, Melanie},
  title     = {Zur Multikausalit{\"a}t von Designentscheidungen - eine Beispielsammlung},
  series = {Designentscheidungen: {\"u}ber Begr{\"u}ndungen im Entwurfsprozess},
  booktitle = {Designentscheidungen: {\"u}ber Begr{\"u}ndungen im Entwurfsprozess},
  publisher = {avedition},
  address   = {Stuttgart},
  isbn      = {978-3-89986-353-6},
  pages     = {22 -- 43},
  year      = {2021},
  language  = {de}
}
@article{DrummEmhardtKoketal.2020,
  author    = {Drumm, Christian and Emhardt, Selina N. and Kok, Ellen M. and Jarodzka, Halzka and Brand-Gruwel, Saskia and van Gog, Tamara},
  title     = {How Experts Adapt Their Gaze Behavior When Modeling a Task to Novices},
  series = {Cognitive science},
  volume    = {44},
  journal   = {Cognitive science},
  number    = {9},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1551-6709},
  doi       = {10.1111/cogs.12893},
  pages     = {26},
  year      = {2020},
  abstract  = {Domain experts regularly teach novice students how to perform a task. This often requires them to adjust their behavior to the less knowledgeable audience and, hence, to behave in a more didactic manner. Eye movement modeling examples (EMMEs) are a contemporary educational tool for displaying experts' (natural or didactic) problem-solving behavior as well as their eye movements to learners. While research on expert-novice communication mainly focused on experts' changes in explicit, verbal communication behavior, it is as yet unclear whether and how exactly experts adjust their nonverbal behavior. This study first investigated whether and how experts change their eye movements and mouse clicks (that are displayed in EMMEs) when they perform a task naturally versus teach a task didactically. Programming experts and novices initially debugged short computer codes in a natural manner. We first characterized experts' natural problem-solving behavior by contrasting it with that of novices. Then, we explored the changes in experts' behavior when being subsequently instructed to model their task solution didactically. Experts became more similar to novices on measures associated with experts' automatized processes (i.e., shorter fixation durations, fewer transitions between code and output per click on the run button when behaving didactically). This adaptation might make it easier for novices to follow or imitate the expert behavior. In contrast, experts became less similar to novices for measures associated with more strategic behavior (i.e., code reading linearity, clicks on run button) when behaving didactically.},
  language  = {en}
}
@unpublished{BornheimGriegerBlanecketal.2023,
  author    = {Bornheim, Tobias and Grieger, Niklas and Blaneck, Patrick Gustav and Bialonski, Stephan},
  title     = {Preprint: Speaker attribution in German parliamentary debates with QLoRA-adapted large language models},
  series = {Journal for Language Technology and Computational Linguistics},
  journal   = {Journal for Language Technology and Computational Linguistics},
  doi       = {10.48550/arXiv.2309.09902},
  pages     = {8 Seiten},
  year      = {2023},
  abstract  = {The growing body of political texts opens up new opportunities for rich insights into political dynamics and ideologies but also increases the workload for manual analysis. Automated speaker attribution, which detects who said what to whom in a speech event and is closely related to semantic role labeling, is an important processing step for computational text analysis. We study the potential of the large language model family Llama 2 to automate speaker attribution in German parliamentary debates from 2017-2021. We fine-tune Llama 2 with QLoRA, an efficient training strategy, and observe our approach to achieve competitive performance in the GermEval 2023 Shared Task On Speaker Attribution in German News Articles and Parliamentary Debates. Our results shed light on the capabilities of large language models in automating speaker attribution, revealing a promising avenue for computational analysis of political discourse and the development of semantic role labeling systems.},
  language  = {en}
}
@techreport{FischedickSchoofHebeletal.2018,
  type      = {Working Paper},
  author    = {Fischedick, Manfred and Schoof, Ren{\´e} and Hebel, Christoph and Merkens, Torsten},
  title     = {Sektorenkopplung als Herausforderung und Chance f{\"u}r das Energieland NRW : Handlungsoptionen und Ergebnispapier der Expertengruppe AG 4 „Sektoren- kopplung" im Netzwerk Netze und Speicher der EnergieAgentur.NRW im Auftrag des Landes Nordrhein-Westfalen / EnergieAgentur.NRW GmbH},
  pages     = {68 Seiten},
  year      = {2018},
  language  = {de}
}
@inproceedings{BornheimGriegerBialonski2021,
  author    = {Bornheim, Tobias and Grieger, Niklas and Bialonski, Stephan},
  title     = {FHAC at GermEval 2021: Identifying German toxic, engaging, and fact-claiming comments with ensemble learning},
  series = {Proceedings of the GermEval 2021 Workshop on the Identification of Toxic, Engaging, and Fact-Claiming Comments : 17th Conference on Natural Language Processing KONVENS 2021},
  booktitle = {Proceedings of the GermEval 2021 Workshop on the Identification of Toxic, Engaging, and Fact-Claiming Comments : 17th Conference on Natural Language Processing KONVENS 2021},
  publisher = {Heinrich Heine University},
  address   = {D{\"u}sseldorf},
  doi       = {10.48415/2021/fhw5-x128},
  pages     = {105 -- 111},
  year      = {2021},
  language  = {en}
}
@book{WagemannTippkoetter2019,
  author    = {Wagemann, Kurt and Tippk{\"o}tter, Nils},
  title     = {Biorefineries / Kurt Wagemann, Nils Tippk{\"o}tter (editors)},
  series = {Advances in biochemical engineering/biotechnology book series (ABE)},
  journal   = {Advances in biochemical engineering/biotechnology book series (ABE)},
  publisher = {Springer},
  address   = {Cham (Switzerland)},
  isbn      = {978-3-319-97117-9},
  doi       = {10.1007/978-3-319-97119-3},
  pages     = {VI, 549 Seiten},
  year      = {2019},
  language  = {en}
}
@incollection{Kurz2022,
  author    = {Kurz, Melanie},
  title     = {Vom Werkbundstreit bis zur Papierformatnormung - welche Rolle der Chemie-Nobelpreistr{\"a}ger Friedrich Wilhelm Ostwald bei Typisierungsbestrebungen im Design spielt},
  series = {Raster, Regeln, Ratio : Systematiken und Normungen des 20. Jahrhunderts},
  volume    = {2022},
  booktitle = {Raster, Regeln, Ratio : Systematiken und Normungen des 20. Jahrhunderts},
  publisher = {avedition},
  address   = {Stuttgart},
  isbn      = {978-3-89986-380-2},
  pages     = {6 -- 17},
  year      = {2022},
  language  = {de}
}
@incollection{Fabo2022,
  author    = {Fabo, Sabine},
  title     = {Pandemische Momente},
  series = {Interaktion - Emotion - Desinfektion ; Kunst und Museum in Zeiten von Corona / Birgit Richard, Jana M{\"u}ller, Niklas von Reischach (Hrsg.)},
  booktitle = {Interaktion - Emotion - Desinfektion ; Kunst und Museum in Zeiten von Corona / Birgit Richard, Jana M{\"u}ller, Niklas von Reischach (Hrsg.)},
  publisher = {Campus},
  address   = {Frankfurt ; New York},
  isbn      = {978-3-593-51520-5 (Print)},
  pages     = {137 -- 140},
  year      = {2022},
  language  = {de}
}
@incollection{Kurz2019,
  author    = {Kurz, Melanie},
  title     = {Betrifft Design : von historischen Zukunftsperspektiven zu gegenw{\"a}rtigen Vergangenheitssehns{\"u}chten},
  series = {Positionen des Neuen : Zukunft im Design},
  booktitle = {Positionen des Neuen : Zukunft im Design},
  publisher = {avedition},
  address   = {Stuttgart},
  isbn      = {978-3-89986-301-7},
  pages     = {136 -- 144},
  year      = {2019},
  language  = {de}
}
@incollection{Finkenberger2018,
  author    = {Finkenberger, Isabel Maria},
  title     = {Schwellenreiten},
  series = {Prozesse reflexiven Entwerfens : Entwerfen und Forschen in Architektur und Landschaft},
  booktitle = {Prozesse reflexiven Entwerfens : Entwerfen und Forschen in Architektur und Landschaft},
  editor    = {Buchert, Margitta},
  publisher = {JOVIS Verlag},
  address   = {Berlin},
  isbn      = {978-3-86859-558-1},
  pages     = {208 -- 226},
  year      = {2018},
  language  = {de}
}
@book{Kurz2018,
  author    = {Kurz, Melanie},
  title     = {Designstreit : exemplarische Kontroversen {\"u}ber Gestaltung},
  publisher = {Wilhelm Fink},
  address   = {Paderborn},
  isbn      = {978-3-7705-6294-7 (Druckausgabe)},
  pages     = {304 Seiten},
  year      = {2018},
  abstract  = {Die Geschichte des Designs ist ges{\"a}umt von Auseinandersetzungen. Debattiert wird unter Berufsgenossen, in Interessensverb{\"a}nden, zwischen Wettbewerbern und nicht zuletzt an Hochschulen; als Foren dienen zum Beispiel Zeitungen, Konferenzen oder Gerichtss{\"a}le. Doch welche Gr{\"u}nde gibt es f{\"u}r Streit {\"u}ber Design? Die Kontroversen beschr{\"a}nken sich keineswegs auf die {\"A}sthetik von Artefakten. Auch haben wir es trotz der Vielfalt an Streitf{\"a}llen nicht mit einem un{\"u}berschaubaren Feld von zusammenhanglosen Einzelereignissen zu tun. Wie das vorliegende Buch anhand historischer Kontroversen zeigt, lassen sich im Bereich der Gestaltung Streitkategorien identifizieren. Die Diskursanalyse verr{\"a}t, dass sich die Konfliktursachen im Verlauf der Designhistorie kaum ver{\"a}ndern. So haben die angef{\"u}hrten Dispute erstaunliche {\"A}hnlichkeit mit aktuellen Debatten im Fach. Sie sind Lehrst{\"u}cke und k{\"o}nnen dazu anregen, eine Streitkultur im Design zu etablieren, die sich davon distanziert, den Meinungsgegner in ein politisches Lager zu ›verr{\"a}umen‹.},
  language  = {de}
}
@book{KurzSchwer2022,
  author    = {Kurz, Melanie and Schwer, Thilo},
  title     = {Geschichte des Designs},
  edition   = {1. Auflage},
  publisher = {Beck},
  address   = {M{\"u}nchen},
  isbn      = {978-3-406-78813-0},
  pages     = {128 Seiten},
  year      = {2022},
  abstract  = {Dieser Band bietet einen kompakten {\"U}berblick {\"u}ber die wichtigsten Stationen des Produktdesigns vom Beginn der Industrialisierung bis heute. Im Zentrum stehen ikonische Alltagsgegenst{\"a}nde vom Thonet-Stuhl bis zum iPhone. Anschaulich und kenntnisreich nehmen Melanie Kurz und Thilo Schwer dabei auch die gesellschaftspolitische Situation, in der die Objekte entstanden sind, in den Blick.},
  language  = {de}
}
@incollection{FinkenbergerBaumeister2017,
  author    = {Finkenberger, Isabel Maria and Baumeister, Eva-Maria},
  title     = {Working in between : Die Stadt von der anderen Seite sehen : Where Urban Planning Meets Artistic Practice},
  series = {New Stakeholders of Urban Change : A Question of Culture and Attitude?. - (Perspectives in Metropolitan Research ; IV)},
  booktitle = {New Stakeholders of Urban Change : A Question of Culture and Attitude?. - (Perspectives in Metropolitan Research ; IV)},
  editor    = {Berger, Hilke Marit and Ziemer, Gesa},
  publisher = {JOVIS Verlag},
  address   = {Berlin},
  isbn      = {978-3-86859-487-4},
  pages     = {119 -- 129},
  year      = {2017},
  language  = {de}
}
@article{Finkenberger2019,
  author    = {Finkenberger, Isabel Maria},
  title     = {Bodenpolitik als Instrument strategischer Transformation},
  series = {UrbanLab-Magazin : Fachzeitschrift f{\"u}r Stadt- und Quartierplanung},
  volume    = {2019},
  journal   = {UrbanLab-Magazin : Fachzeitschrift f{\"u}r Stadt- und Quartierplanung},
  number    = {05},
  pages     = {18 -- 25},
  year      = {2019},
  language  = {de}
}
@article{FinkenbergerVeil2020,
  author    = {Finkenberger, Isabel Maria and Veil, Katja},
  title     = {R{\"a}umliche Transformation},
  series = {RaumPlanung : Fachzeitschrift f{\"u}r r{\"a}umliche Planung und Forschung},
  volume    = {205},
  journal   = {RaumPlanung : Fachzeitschrift f{\"u}r r{\"a}umliche Planung und Forschung},
  number    = {1},
  publisher = {IfR (Informationskreis f{\"u}r Raumplanung)},
  address   = {Dortmund},
  issn      = {0176-7534},
  pages     = {6 -- 11},
  year      = {2020},
  language  = {de}
}
@incollection{Fabo2022,
  author    = {Fabo, Sabine},
  title     = {Pl{\"u}schviren - Zur Konstruktion von N{\"a}he in Zeiten der Pandemie},
  series = {Interaktion - Emotion - Desinfektion ; Kunst und Museum in Zeiten von Corona / Birgit Richard, Jana M{\"u}ller, Niklas von Reischach (Hrsg.)},
  booktitle = {Interaktion - Emotion - Desinfektion ; Kunst und Museum in Zeiten von Corona / Birgit Richard, Jana M{\"u}ller, Niklas von Reischach (Hrsg.)},
  publisher = {Campus},
  address   = {Frankfurt ; New York},
  isbn      = {978-3-593-51520-5 (Print)},
  pages     = {45 -- 69},
  year      = {2022},
  language  = {de}
}
@book{KurzSchwer2021,
  author    = {Kurz, Melanie and Schwer, Thilo},
  title     = {Designentscheidungen : {\"u}ber Begr{\"u}ndungen im Entwurfsprozess / herausgegeben von Melanie Kurz und Thilo Schwer},
  series = {Schriften / Gesellschaft f{\"u}r Designgeschichte},
  journal   = {Schriften / Gesellschaft f{\"u}r Designgeschichte},
  publisher = {avedition},
  address   = {Stuttgart},
  isbn      = {978-3-89986-353-6},
  pages     = {143 Seiten : Illustrationen},
  year      = {2021},
  language  = {de}
}
@incollection{Fabo2017,
  author    = {Fabo, Sabine},
  title     = {Das Dokumentarische als offene Konstruktion},
  series = {Doris Frohnapfel, Documentary derivative},
  booktitle = {Doris Frohnapfel, Documentary derivative},
  publisher = {Totalverlag},
  address   = {K{\"o}ln},
  isbn      = {978-3-942040-03-7},
  pages     = {5 -- 23},
  year      = {2017},
  language  = {de}
}
@article{Kurz2018,
  author    = {Kurz, Melanie},
  title     = {Was heißt: Verantwortung im Design? Historische Positionen},
  series = {Boxhorn: das Magazin aus dem Fachbereich Gestaltung der FH Aachen},
  journal   = {Boxhorn: das Magazin aus dem Fachbereich Gestaltung der FH Aachen},
  number    = {34},
  address   = {Aachen},
  pages     = {26 -- 33},
  year      = {2018},
  language  = {de}
}
@article{AliaziziOezsoyluBakhshiSichanietal.2024,
  author    = {Aliazizi, Fereshteh and {\"O}zsoylu, Dua and Bakhshi Sichani, Soroush and Khorshid, Mehran and Glorieux, Christ and Robbens, Johan and Sch{\"o}ning, Michael Josef and Wagner, Patrick},
  title     = {Development and Calibration of a Microfluidic, Chip-Based Sensor System for Monitoring the Physical Properties of Water Samples in Aquacultures},
  series = {Micromachines},
  volume    = {15},
  journal   = {Micromachines},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2072-666X},
  doi       = {10.3390/mi15060755},
  year      = {2024},
  abstract  = {In this work, we present a compact, bifunctional chip-based sensor setup that measures the temperature and electrical conductivity of water samples, including specimens from rivers and channels, aquaculture, and the Atlantic Ocean. For conductivity measurements, we utilize the impedance amplitude recorded via interdigitated electrode structures at a single triggering frequency. The results are well in line with data obtained using a calibrated reference instrument. The new setup holds for conductivity values spanning almost two orders of magnitude (river versus ocean water) without the need for equivalent circuit modelling. Temperature measurements were performed in four-point geometry with an on-chip platinum RTD (resistance temperature detector) in the temperature range between 2 °C and 40 °C, showing no hysteresis effects between warming and cooling cycles. Although the meander was not shielded against the liquid, the temperature calibration provided equivalent results to low conductive Milli-Q and highly conductive ocean water. The sensor is therefore suitable for inline and online monitoring purposes in recirculating aquaculture systems.},
  language  = {en}
}
@phdthesis{Biewendt2022,
  author    = {Biewendt, Marcel},
  title     = {Socio-Economic challenges in sustainability and resource management},
  publisher = {Hungarian University of Agriculture and Life Sciences},
  pages     = {160 Seiten},
  year      = {2022},
  abstract  = {This dissertation uses in first stage a macroeconomic investigation to examine the dependence, influence and corruption of socio-economic development through effects of sustainability and resource management. The conducted research found that the state's dependence on its citizens decreases when the state's sources of revenue are largely detached and independent of the citizens' financial resources. In this case, financial resources are taxes and duties provided by the citizens. One possible consequence is the restriction of state investment in its citizens. Both the qualitative literature review and the quantitative data analysis revealed a negative correlation between socio-economic development and the resource economy's share of GDP for the period under study. The microeconomic investigation was primarily conducted through an intensive literature review. It was shown that the rebound effect as such is already very well researched. However, it also became clear that avoidance strategies for the rebound effect and links to sustainability initiatives are scarce or non-existent. The need for a redesign of the impact analysis with regard to technological innovations and their influence on resource consumption and resource management has become clear on the basis of the present study. Further, emerging and developing countries in particular, which will be confronted in the foreseeable future not only with the fundamental problems of resource abundance in the overall economic context, but also with the issues of their sustainable use, should be confronted with these problems as early as possible in order to find solutions in a timely manner.},
  language  = {de}
}
@misc{LippoldtRingbeckHuening2023,
  author    = {Lippoldt, Mario and Ringbeck, Thorsten and H{\"u}ning, Felix},
  title     = {Verfahren und System zur Erkennung von unerlaubten Fahrzeug-{\"U}berholvorg{\"a}ngen in einer {\"U}berholverbotszone eines Fahrwegs},
  year      = {2023},
  language  = {de}
}
@misc{BiewendtBlaschkeBoehnert2019,
  author    = {Biewendt, Marcel and Blaschke, Florian and B{\"o}hnert, Arno},
  title     = {The rebound effect: a critical and systematic review on the current state of affairs},
  series = {Abstracts of the International Conference on Sustainable Economy and Agriculture},
  journal   = {Abstracts of the International Conference on Sustainable Economy and Agriculture},
  editor    = {Koponicsne Gy{\"o}rke, Diana},
  publisher = {Universit{\"a}t Kaposv{\´a}r},
  address   = {Kaposv{\´a}r},
  isbn      = {978-615-5599-72-9},
  pages     = {101 -- 101},
  year      = {2019},
  language  = {en}
}
@article{BayerTemizArtmannDigeletal.2020,
  author    = {Bayer, Robin and Temiz Artmann, Ayseg{\"u}l and Digel, Ilya and Falkenstein, Julia and Artmann, Gerhard and Creutz, Till and Hescheler, J{\"u}rgen},
  title     = {Mechano-pharmacological testing of L-Type Ca²⁺ channel modulators via human vascular celldrum model},
  series = {Cellular Physiology and Biochemistry},
  volume    = {54},
  journal   = {Cellular Physiology and Biochemistry},
  publisher = {Cell Physiol Biochem Press},
  address   = {D{\"u}sseldorf},
  issn      = {1421-9778},
  doi       = {10.33594/000000225},
  pages     = {371 -- 383},
  year      = {2020},
  abstract  = {Background/Aims: This study aimed to establish a precise and well-defined working model, assessing pharmaceutical effects on vascular smooth muscle cell monolayer in-vitro. It describes various analysis techniques to determine the most suitable to measure the biomechanical impact of vasoactive agents by using CellDrum technology. Methods: The so-called CellDrum technology was applied to analyse the biomechanical properties of confluent human aorta muscle cells (haSMC) in monolayer. The cell generated tensions deviations in the range of a few N/m² are evaluated by the CellDrum technology. This study focuses on the dilative and contractive effects of L-type Ca²⁺ channel agonists and antagonists, respectively. We analyzed the effects of Bay K8644, nifedipine and verapamil. Three different measurement modes were developed and applied to determine the most appropriate analysis technique for the study purpose. These three operation modes are called, particular time mode" (PTM), "long term mode" (LTM) and "real-time mode" (RTM). Results: It was possible to quantify the biomechanical response of haSMCs to the addition of vasoactive agents using CellDrum technology. Due to the supplementation of 100nM Bay K8644, the tension increased approximately 10.6\% from initial tension maximum, whereas, the treatment with nifedipine and verapamil caused a significant decrease in cellular tension: 10nM nifedipine decreased the biomechanical stress around 6,5\% and 50nM verapamil by 2,8\%, compared to the initial tension maximum. Additionally, all tested measurement modes provide similar results while focusing on different analysis parameters. Conclusion: The CellDrum technology allows highly sensitive biomechanical stress measurements of cultured haSMC monolayers. The mechanical stress responses evoked by the application of vasoactive calcium channel modulators were quantified functionally (N/m²). All tested operation modes resulted in equal findings, whereas each mode features operation-related data analysis.},
  language  = {en}
}
@article{UysalCreutzFiratetal.2022,
  author    = {Uysal, Karya and Creutz, Till and Firat, Ipek Seda and Artmann, Gerhard and Teusch, Nicole and Temiz Artmann, Ayseg{\"u}l},
  title     = {Bio-functionalized ultra-thin, large-area and waterproof silicone membranes for biomechanical cellular loading and compliance experiments},
  series = {Polymers},
  volume    = {14},
  journal   = {Polymers},
  number    = {11},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2073-4360},
  pages     = {2213},
  year      = {2022},
  abstract  = {Biocompatibility, flexibility and durability make polydimethylsiloxane (PDMS) membranes top candidates in biomedical applications. CellDrum technology uses large area, <10 µm thin membranes as mechanical stress sensors of thin cell layers. For this to be successful, the properties (thickness, temperature, dust, wrinkles, etc.) must be precisely controlled. The following parameters of membrane fabrication by means of the Floating-on-Water (FoW) method were investigated: (1) PDMS volume, (2) ambient temperature, (3) membrane deflection and (4) membrane mechanical compliance. Significant differences were found between all PDMS volumes and thicknesses tested (p < 0.01). They also differed from the calculated values. At room temperatures between 22 and 26 °C, significant differences in average thickness values were found, as well as a continuous decrease in thicknesses within a 4 °C temperature elevation. No correlation was found between the membrane thickness groups (between 3-4 µm) in terms of deflection and compliance. We successfully present a fabrication method for thin bio-functionalized membranes in conjunction with a four-step quality management system. The results highlight the importance of tight regulation of production parameters through quality control. The use of membranes described here could also become the basis for material testing on thin, viscous layers such as polymers, dyes and adhesives, which goes far beyond biological applications.},
  language  = {en}
}
@article{RaffeisAdjeiKyeremehVroomenetal.2020,
  author    = {Raffeis, Iris and Adjei-Kyeremeh, Frank and Vroomen, Uwe and Westhoff, Elmar and Bremen, Sebastian and Hohoi, Alexandru and B{\"u}hrig-Polaczek, Andreas},
  title     = {Qualification of a Ni-Cu alloy for the laser powder bed fusion process (LPBF): Its microstructure and mechanical properties},
  series = {Applied Sciences},
  volume    = {10},
  journal   = {Applied Sciences},
  number    = {Art. 3401},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2076-3417},
  doi       = {10.3390/app10103401},
  pages     = {1 -- 15},
  year      = {2020},
  abstract  = {As researchers continue to seek the expansion of the material base for additive manufacturing, there is a need to focus attention on the Ni-Cu group of alloys which conventionally has wide industrial applications. In this work, the G-NiCu30Nb casting alloy, a variant of the Monel family of alloys with Nb and high Si content is, for the first time, processed via the laser powder bed fusion process (LPBF). Being novel to the LPBF processes, optimum LPBF parameters were determined, and hardness and tensile tests were performed in as-built conditions and after heat treatment at 1000 °C. Microstructures of the as-cast and the as-built condition were compared. Highly dense samples (99.8\% density) were achieved after varying hatch distance (80 µm and 140 µm) with scanning speed (550 mm/s-1500 mm/s). There was no significant difference in microhardness between varied hatch distance print sets. Microhardness of the as-built condition (247 HV0.2) exceeded the as-cast microhardness (179 HV0.2.). Tensile specimens built in vertical (V) and horizontal (H) orientations revealed degrees of anisotropy and were superior to conventionally reported figures. Post heat treatment increased ductility from 20\% to 31\% (V), as well as from 16\% to 25\% (H), while ultimate tensile strength (UTS) and yield strength (YS) were considerably reduced.},
  language  = {en}
}
@article{UysalFiratCreutzetal.2022,
  author    = {Uysal, Karya and Firat, Ipek Serat and Creutz, Till and Aydin, Inci Cansu and Artmann, Gerhard and Teusch, Nicole and Temiz Artmann, Ayseg{\"u}l},
  title     = {A novel in vitro wound healing assay using free-standing, ultra-thin PDMS membranes},
  series = {membranes},
  volume    = {2023},
  journal   = {membranes},
  number    = {13(1)},
  publisher = {MDPI},
  address   = {Basel},
  doi       = {10.3390/membranes13010022},
  pages     = {Artikel 22},
  year      = {2022},
  abstract  = {Advances in polymer science have significantly increased polymer applications in life sciences. We report the use of free-standing, ultra-thin polydimethylsiloxane (PDMS) membranes, called CellDrum, as cell culture substrates for an in vitro wound model. Dermal fibroblast monolayers from 28- and 88-year-old donors were cultured on CellDrums. By using stainless steel balls, circular cell-free areas were created in the cell layer (wounding). Sinusoidal strain of 1 Hz, 5\% strain, was applied to membranes for 30 min in 4 sessions. The gap circumference and closure rate of un-stretched samples (controls) and stretched samples were monitored over 4 days to investigate the effects of donor age and mechanical strain on wound closure. A significant decrease in gap circumference and an increase in gap closure rate were observed in trained samples from younger donors and control samples from older donors. In contrast, a significant decrease in gap closure rate and an increase in wound circumference were observed in the trained samples from older donors. Through these results, we propose the model of a cell monolayer on stretchable CellDrums as a practical tool for wound healing research. The combination of biomechanical cell loading in conjunction with analyses such as gene/protein expression seems promising beyond the scope published here.},
  language  = {en}
}
@inproceedings{KaschSchmidtEichleretal.2020,
  author    = {Kasch, Susanne and Schmidt, Thomas and Eichler, Fabian and Thurn, Laura and Jahn, Simon and Bremen, Sebastian},
  title     = {Solution approaches and process concepts for powder bed-based melting of glass},
  series = {Industrializing Additive Manufacturing. Proceedings of AMPA2020},
  booktitle = {Industrializing Additive Manufacturing. Proceedings of AMPA2020},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-54333-4 (Print)},
  doi       = {10.1007/978-3-030-54334-1_7},
  pages     = {82 -- 95},
  year      = {2020},
  abstract  = {In the study, the process chain of additive manufacturing by means of powder bed fusion will be presented based on the material glass. In order to reliably process components additively, new concepts with different solutions were developed and investigated. Compared to established metallic materials, the properties of glass materials differ significantly. Therefore, the process control was adapted to the material glass in the investigations. With extensive parameter studies based on various glass powders such as borosilicate glass and quartz glass, scientifically proven results on powder bed fusion of glass are presented. Based on the determination of the particle properties with different methods, extensive investigations are made regarding the melting behavior of glass by means of laser beams. Furthermore, the experimental setup was steadily expanded. In addition to the integration of coaxial temperature measurement and regulation, preheating of the building platform is of major importance. This offers the possibility to perform 3D printing at the transformation temperatures of the glass materials. To improve the component's properties, the influence of a subsequent heat treatment was also investigated. The experience gained was incorporated into a new experimental system, which allows a much better exploration of the 3D printing of glass. Currently, studies are being conducted to improve surface texture, building accuracy, and geometrical capabilities using three-dimensional specimen. The contribution shows the development of research in the field of 3D printing of glass, gives an insight into the machine and process engineering as well as an outlook on the possibilities and applications.},
  language  = {en}
}
@inproceedings{WeissHeslenfeldSaeweetal.2022,
  author    = {Weiss, Christian and Heslenfeld, Jonas and Saewe, Jasmin Kathrin and Bremen, Sebastian and H{\"a}fner, Constantin Leon},
  title     = {Investigation on the influence of powder humidity in Laser Powder Bed Fusion (LPBF)},
  series = {Procedia CIRP 12th CIRP Conference on Photonic Technologies [LANE 2022]},
  volume    = {111},
  booktitle = {Procedia CIRP 12th CIRP Conference on Photonic Technologies [LANE 2022]},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2212-8271},
  doi       = {10.1016/j.procir.2022.08.102},
  pages     = {115 -- 120},
  year      = {2022},
  abstract  = {In the Laser Powder Bed Fusion (LPBF) process, parts are built out of metal powder material by exposure of a laser beam. During handling operations of the powder material, several influencing factors can affect the properties of the powder material and therefore directly influence the processability during manufacturing. Contamination by moisture due to handling operations is one of the most critical aspects of powder quality. In order to investigate the influences of powder humidity on LPBF processing, four materials (AlSi10Mg, Ti6Al4V, 316L and IN718) are chosen for this study. The powder material is artificially humidified, subsequently characterized, manufactured into cubic samples in a miniaturized process chamber and analyzed for their relative density. The results indicate that the processability and reproducibility of parts made of AlSi10Mg and Ti6Al4V are susceptible to humidity, while IN718 and 316L are barely influenced.},
  language  = {en}
}
@article{TemizArtmannKurulgandemirciFıratetal.2021,
  author    = {Temiz Artmann, Ayseg{\"u}l and Kurulgan demirci, Eylem and F{\i}rat, Ipek Seda and Oflaz, Hakan and Artmann, Gerhard},
  title     = {Recombinant activated protein C (rhAPC) affects lipopolysaccharide-induced mechanical compliance changes and beat frequency of mESC-derived cardiomyocyte monolayers},
  series = {SHOCK},
  journal   = {SHOCK},
  publisher = {Wolters Kluwer},
  address   = {K{\"o}ln},
  issn      = {1540-0514},
  doi       = {10.1097/SHK.0000000000001845},
  year      = {2021},
  language  = {en}
}
@article{KaschSchmidtJahnetal.2021,
  author    = {Kasch, Susanne and Schmidt, Thomas and Jahn, Simon and Eichler, Fabian and Thurn, Laura and Bremen, Sebastian},
  title     = {L{\"o}sungsans{\"a}tze und Verfahrenskonzepte zum Laserstrahlschmelzen von Glas},
  series = {Schweissen und Schneiden},
  volume    = {73},
  journal   = {Schweissen und Schneiden},
  number    = {Heft 1-2},
  publisher = {DVS Verlag},
  address   = {D{\"u}sseldorf},
  isbn      = {0036-7184},
  pages     = {32 -- 39},
  year      = {2021},
  language  = {de}
}
@article{GossmannFrotscherLinderetal.2016,
  author    = {Goßmann, Matthias and Frotscher, Ralf and Linder, Peter and Bayer, Robin and Epple, U. and Staat, Manfred and Temiz Artmann, Ayseg{\"u}l and Artmann, Gerhard},
  title     = {Mechano-pharmacological characterization of cardiomyocytes derived from human induced pluripotent stem cells},
  series = {Cellular physiology and biochemistry},
  volume    = {38},
  journal   = {Cellular physiology and biochemistry},
  number    = {3},
  publisher = {Karger},
  address   = {Basel},
  issn      = {1421-9778 (Online)},
  doi       = {10.1159/000443124},
  pages     = {1182 -- 1198},
  year      = {2016},
  abstract  = {Background/Aims: Common systems for the quantification of cellular contraction rely on animal-based models, complex experimental setups or indirect approaches. The herein presented CellDrum technology for testing mechanical tension of cellular monolayers and thin tissue constructs has the potential to scale-up mechanical testing towards medium-throughput analyses. Using hiPS-Cardiac Myocytes (hiPS-CMs) it represents a new perspective of drug testing and brings us closer to personalized drug medication. Methods: In the present study, monolayers of self-beating hiPS-CMs were grown on ultra-thin circular silicone membranes and deflect under the weight of the culture medium. Rhythmic contractions of the hiPS-CMs induced variations of the membrane deflection. The recorded contraction-relaxation-cycles were analyzed with respect to their amplitudes, durations, time integrals and frequencies. Besides unstimulated force and tensile stress, we investigated the effects of agonists and antagonists acting on Ca²⁺ channels (S-Bay K8644/verapamil) and Na⁺ channels (veratridine/lidocaine). Results: The measured data and simulations for pharmacologically unstimulated contraction resembled findings in native human heart tissue, while the pharmacological dose-response curves were highly accurate and consistent with reference data. Conclusion: We conclude that the combination of the CellDrum with hiPS-CMs offers a fast, facile and precise system for pharmacological, toxicological studies and offers new preclinical basic research potential.},
  language  = {en}
}
@article{LuftLuftArntz2023,
  author    = {Luft, Angela and Luft, Nils and Arntz, Kristian},
  title     = {A basic description logic for service-oriented architecture in factory planning and operational control in the age of industry 4.0},
  series = {Applied Sciences},
  volume    = {2023},
  journal   = {Applied Sciences},
  number    = {13},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2076-3417},
  doi       = {10.3390/app13137610},
  pages     = {23 Seiten},
  year      = {2023},
  abstract  = {Manufacturing companies across multiple industries face an increasingly dynamic and unpredictable environment. This development can be seen on both the market and supply side. To respond to these challenges, manufacturing companies must implement smart manufacturing systems and become more flexible and agile. The flexibility in operational planning regarding the scheduling and sequencing of customer orders needs to be increased and new structures must be implemented in manufacturing systems' fundamental design as they constitute much of the operational flexibility available. To this end, smart and more flexible solutions for production planning and control (PPC) are developed. However, scheduling or sequencing is often only considered isolated in a predefined stable environment. Moreover, their orientation on the fundamental logic of the existing IT solutions and their applicability in a dynamic environment is limited. This paper presents a conceptual model for a task-based description logic that can be applied to factory planning, technology planning, and operational control. By using service-oriented architectures, the goal is to generate smart manufacturing systems. The logic is designed to allow for easy and automated maintenance. It is compatible with the existing resource and process allocation logic across operational and strategic factory and production planning.},
  language  = {en}
}
@article{ArinkinDigelPorstetal.2014,
  author    = {Arinkin, Vladimir and Digel, Ilya and Porst, Dariusz and Temiz Artmann, Ayseg{\"u}l and Artmann, Gerhard},
  title     = {Phenotyping date palm varieties via leaflet cross-sectional imaging and artificial neural network application},
  series = {BMC bioinformatics},
  volume    = {15},
  journal   = {BMC bioinformatics},
  number    = {55},
  issn      = {1471-2105},
  doi       = {10.1186/1471-2105-15-55},
  pages     = {1 -- 8},
  year      = {2014},
  abstract  = {Background True date palms (Phoenix dactylifera L.) are impressive trees and have served as an indispensable source of food for mankind in tropical and subtropical countries for centuries. The aim of this study is to differentiate date palm tree varieties by analysing leaflet cross sections with technical/optical methods and artificial neural networks (ANN). Results Fluorescence microscopy images of leaflet cross sections have been taken from a set of five date palm tree cultivars (Hewlat al Jouf, Khlas, Nabot Soltan, Shishi, Um Raheem). After features extraction from images, the obtained data have been fed in a multilayer perceptron ANN with backpropagation learning algorithm. Conclusions Overall, an accurate result in prediction and differentiation of date palm tree cultivars was achieved with average prediction in tenfold cross-validation is 89.1\% and reached 100\% in one of the best ANN.},
  language  = {en}
}
@article{KowalewskiBragardHueningetal.2023,
  author    = {Kowalewski, Paul and Bragard, Michael and H{\"u}ning, Felix and De Doncker, Rik W.},
  title     = {An inexpensive Wiegand-sensor-based rotary encoder without rotating magnets for use in electrical drives},
  series = {IEEE Transactions on Instrumentation and Measurement},
  volume    = {72},
  journal   = {IEEE Transactions on Instrumentation and Measurement},
  publisher = {IEEE},
  address   = {New York},
  issn      = {0018-9456 (Print)},
  doi       = {10.1109/TIM.2023.3326166},
  pages     = {10 Seiten},
  year      = {2023},
  abstract  = {This paper introduces an inexpensive Wiegand-sensor-based rotary encoder that avoids rotating magnets and is suitable for electrical-drive applications. So far, Wiegand-sensor-based encoders usually include a magnetic pole wheel with rotating permanent magnets. These encoders combine the disadvantages of an increased magnet demand and a limited maximal speed due to the centripetal force acting on the rotating magnets. The proposed approach reduces the total demand of permanent magnets drastically. Moreover, the rotating part is manufacturable from a single piece of steel, which makes it very robust and cheap. This work presents the theoretical operating principle of the proposed approach and validates its benefits on a hardware prototype. The presented proof-of-concept prototype achieves a mechanical resolution of 4.5 ° by using only 4 permanent magnets, 2Wiegand sensors and a rotating steel gear wheel with 20 teeth.},
  language  = {en}
}
@article{MiciliValterOflazetal.2013,
  author    = {Micili, Serap C. and Valter, Markus and Oflaz, Hakan and Ozogul, Candan and Linder, Peter and F{\"o}ckler, Nicole and Artmann, Gerhard and Digel, Ilya and Temiz Artmann, Ayseg{\"u}l},
  title     = {Optical coherence tomography : a potential tool to predict premature rupture of fetal membranes},
  series = {Proceedings of the Institution of Mechanical Engineers. Part H : Journal of engineering in medicine},
  volume    = {Vol. 227},
  journal   = {Proceedings of the Institution of Mechanical Engineers. Part H : Journal of engineering in medicine},
  number    = {No. 4},
  publisher = {Sage},
  address   = {London},
  issn      = {0046-2039 (Print) ; 2041-3033 (E-Journal)},
  pages     = {393 -- 401},
  year      = {2013},
  language  = {en}
}
@article{SeifarthGrosseGrossmannetal.2017,
  author    = {Seifarth, Volker and Grosse, Joachim O. and Grossmann, Matthias and Janke, Heinz Peter and Arndt, Patrick and Koch, Sabine and Epple, Matthias and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l},
  title     = {Mechanical induction of bi-directional orientation of primary porcine bladder smooth muscle cells in tubular fibrin-poly(vinylidene fluoride) scaffolds for ureteral and urethral repair using cyclic and focal balloon catheter stimulation},
  series = {Journal of Biomaterials Applications},
  volume    = {32},
  journal   = {Journal of Biomaterials Applications},
  number    = {3},
  publisher = {Sage},
  address   = {London},
  issn      = {1530-8022},
  doi       = {10.1177/0885328217723178},
  pages     = {321 -- 330},
  year      = {2017},
  language  = {en}
}
@article{SeifarthGossmannGrosseetal.2015,
  author    = {Seifarth, Volker and Goßmann, Matthias and Grosse, J. O. and Becker, C. and Heschel, I. and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l},
  title     = {Development of a Bioreactor to Culture Tissue Engineered Ureters Based on the Application of Tubular OPTIMAIX 3D Scaffolds},
  series = {Urologia Internationalis},
  volume    = {2015},
  journal   = {Urologia Internationalis},
  number    = {95},
  publisher = {Karger},
  address   = {Basel},
  issn      = {0042-1138},
  doi       = {10.1159/000368419},
  pages     = {106 -- 113},
  year      = {2015},
  language  = {en}
}
@masterthesis{Zeyen2024,
  type      = {Bachelor Thesis},
  author    = {Zeyen, Kim},
  title     = {Seeds : Konzeption und Gestaltung eines Toolkits f{\"u}r die Entwicklung nachhaltiger Webdesigns},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {197 Seiten},
  year      = {2024},
  abstract  = {Die Menschheit lebt {\"u}ber ihre Verhältnisse: Permanent {\"u}bersteigt unser Verbrauch die uns j{\"a}hrlich zur Verf{\"u}gung stehenden Ressourcen. Der Energiebedarf digitaler Anwendungen wird dabei meist unterschätzt. Wie Interaction-Designer:innen einen Beitrag zur Entwicklung nachhaltiger Websites leisten können, ist aktuell nur durch aufwendige Recherche zu beantworten. Die Bachelorarbeit »Seeds« stellt einen Schritt im Prozess zu mehr Nachhaltigkeit dar. Sie umfasst ein Toolkit, bestehend aus einer Website und einem Plugin f{\"u}r g{\"a}ngige Designtools. Dieses b{\"u}ndelt alle Informationen, um das Internet barriereärmer, sozialer, ethischer und eben auch ökologisch verträglicher zu gestalten. W{\"a}hrend die Website eine Anlaufstelle f{\"u}r den Wissensaufbau darstellt, unterst{\"u}tzt das Plugin bei der Entwicklung eigener Designs, ohne dass Gestalter:innen den Designprozess verlassen m{\"u}ssen.},
  language  = {de}
}
@masterthesis{Esser2024,
  type      = {Bachelor Thesis},
  author    = {Esser, Julius},
  title     = {Ecosystems : Neuinterpretation von Elementen der Savanne zu Objekten zwischen Kunst und Design.},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {390 Seiten},
  year      = {2024},
  abstract  = {Das Projekt „Ecosystems" (deutsch {\"O}kosysteme) beschreibt die zusammenh{\"a}ngende Entwicklung eines Produktsystems, inspiriert von einzelnen Elementen der afrikanischen Savanne. Das {\"O}kosystem und alle damit verbundenen Strukturen werden als Grundlage f{\"u}r die Konzeption der Objekte genutzt und fortlaufend weitgehend abstrahiert. Die Produktkollektion, bestehend aus sechs verschiedenen M{\"o}beln und Objekten, stellt zusammen das {\"O}kosystem der afrikanischen Savanne dar. Elemente der Savanne k{\"o}nnen ganz unterschiedlicher Natur sein. Sowohl die bekannten Tiere, wie die sogenannten Big Five, kleine Savannenbewohner:innen oder unterschiedliche Pflanzen bilden zusammen die Grundlage f{\"u}r das {\"O}kosystem. Jedes Objekt bezieht die Inspiration dabei aus einem anderen Element der Savanne. Die Grundlage der Objekte bildet dabei nicht allein das optische Erscheinungsbild der Tiere und Pflanzen, sondern vielmehr die damit verbundenen Emotionen und Reaktionen.},
  language  = {de}
}
@masterthesis{Bonsu2024,
  type      = {Bachelor Thesis},
  author    = {Bonsu, Joel},
  title     = {HypnoStress : Implementierung eines Stressmanagement-Controllers f{\"u}r den schulischen Alltag in der Grundschule.},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {145 Seiten},
  year      = {2024},
  abstract  = {In der heutigen Welt sind Kinder in zunehmendem Maße Stress aus verschiedenen Quellen wie schulischen Anforderungen, famili{\"a}rem Druck und ungewohnten Situationen ausgesetzt. Dieser Aspekt wird von vielen Erwachsenen oft vernachl{\"a}ssigt. Das kann dazu f{\"u}hren, dass sich bei Kindern Frustration und {\"A}rger aufstauen. Insbesondere das schulische Umfeld stellt ein erhebliches Stresspotenzial dar, da von den Kindern hohe Leistungen erwartet werden. Leistungsdruck, soziale Erwartungen und Frustration tragen zu diesem Eindruck bei. Auch der Unterricht bildet da keine Ausnahme und ist aufgrund seiner zentralen Bedeutung eine potenzielle Stressquelle. Als spezialisierter Begleiter bietet HypnoStress den Kindern die M{\"o}glichkeit, mit hypnosebasierten Techniken die Stressoren des Alltags zu bew{\"a}ltigen und sich auf neue Herausforderungen vorzubereiten.},
  language  = {de}
}
@masterthesis{Wiese2024,
  type      = {Bachelor Thesis},
  author    = {Wiese, Katharina},
  title     = {Drink me},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {39 Seiten},
  year      = {2024},
  abstract  = {„Drink me" ist ein Kurzfilm {\"u}ber drei Freunde auf einer Party, auf der ein mysteri{\"o}ses Getr{\"a}nk verteilt wird, das die Partyg{\"a}ste in einen besonderen Rausch versetzt. Die Farben fangen an zu leuchten, die Musik wird klarer, alles f{\"u}hlt sich intensiver an. Bis sich die Wahrnehmung der Protagonistin Ally pl{\"o}tzlich ver{\"a}ndert: Vom bunt leuchtenden Rauschzustand zur scheinbaren Realit{\"a}t: Einem grauen, kalten Bunker voller abgewrackter Gestalten. Ally versucht die Party zu verlassen, doch w{\"a}hrend ihre Wahrnehmungen immer weiter verschwimmen, verliert sie gleichzeitig allm{\"a}hlich ihr Bewusstsein. Der Film bietet durch die Darstellung der verschiedenen Wahrnehmungszust{\"a}nde und das Verschwimmen derer ein visuell besonders spannendes Erlebnis.},
  language  = {de}
}
@masterthesis{Naujoks2024,
  type      = {Bachelor Thesis},
  author    = {Naujoks, Christian},
  title     = {Tracking healthy habits : Digitale Anwendung zur F{\"o}rderung von gesunder Ern{\"a}hrung und Verhalten},
  publisher = {FH Aachen},
  address   = {Aachen},
  pages     = {293 Seiten},
  year      = {2024},
  abstract  = {"Tracking healthy habits" ist eine App, die darauf abzielt, ges{\"u}ndere Essgewohnheiten und mehr Bewegung zu f{\"o}rdern, indem sie verschiedene messbare Metriken erfasst. Die Anwendung legt einen besonderen Schwerpunkt auf das Verfolgen von Kalorien, um Nutzer:innen dabei zu helfen, ihre t{\"a}gliche Kalorienaufnahme zu kontrollieren und ein besseres Verst{\"a}ndnis f{\"u}r Lebensmittel zu entwickeln. Ein {\"u}berm{\"a}ßiger Konsum ungesunder Lebensmittel und Bewegungsmangel k{\"o}nnen sich negativ auf den geistigen und k{\"o}rperlichen Zustand auswirken. Daher unterst{\"u}tzt diese App Nutzer:innen dabei, ges{\"u}ndere Gewohnheiten zu entwickeln und Disziplin zu f{\"o}rdern. Die Hauptziele von "Tracking Healthy Habits" sind die F{\"o}rderung ges{\"u}nderer Essgewohnheiten, die Unterst{\"u}tzung langfristiger Verhaltens{\"a}nderungen durch kontinuierliches Monitoring und die Verbesserung der k{\"o}rperlichen sowie geistigen Gesundheit.},
  language  = {de}
}
@masterthesis{Plevako2024,
  type      = {Bachelor Thesis},
  author    = {Plevako, Ludmilla},
  title     = {Ekatharina : Leben in der Trudarmee},
  publisher = {FH Aachen},
  address   = {Aachen},
  pages     = {59 Seiten},
  year      = {2024},
  abstract  = {Harte Arbeit, Hunger, Unterk{\"u}hlung und Ungewissheit - dies war der normale Alltag der Trudarmee im 2. Weltkrieg. Ekatharina, eine deutsche Sowjetb{\"u}rgerin, wurde wie viele andere gegen ihren Willen in diese Armee eingezogen. Die Bachelorarbeit „Ekatharina - Leben in der Trudarmee" behandelt den Lebensabschnitt einer {\"U}berlebenden, der Urgroßmutter der Autorin, in Form eines Graphic Novels. In der Trudarmee, auch Arbeitsarmee genannt, musste sie unter schweren Bedingungen Zwangsarbeit verrichten, wie arbeiten in der Schmiede, B{\"a}ume f{\"a}llen oder St{\"a}mme schleppen. Das Projekt soll nicht nur die Erinnerungen und das kulturelle Gut bewahren, es soll auch die Familiengeschichte erforschen, die Vergangenheit verst{\"a}ndlich gestalten und die beteiligten Personen in Ehren halten.},
  language  = {de}
}
@inproceedings{SchulzeBuxlohGross2021,
  author    = {Schulze-Buxloh, Lina and Groß, Rolf Fritz},
  title     = {Interdisciplinary Course Smart Building Engineering: A new approach of teaching freshmen in remote teamwork project under pandemic restrictions},
  series = {New Perspectives in Science Education - International Conference},
  booktitle = {New Perspectives in Science Education - International Conference},
  publisher = {Filodiritto},
  address   = {Bologna},
  pages     = {4 Seiten},
  year      = {2021},
  abstract  = {In the context of the Corona pandemic and its impact on teaching like digital lectures and exercises a new concept especially for freshmen in demanding courses of Smart Building Engineering became necessary. As there were hardly any face-to-face events at the university, the new teaching concept should enable a good start into engineering studies under pandemic conditions anyway and should also replace the written exam at the end. The students should become active themselves in small teams instead of listening passively to a lecture broadcast online with almost no personal contact. For this purpose, a role play was developed in which the freshmen had to work out a complete solution to the realistic problem of designing, construction planning and implementing a small guesthouse. Each student of the team had to take a certain role like architect, site manager, BIM-manager, electrician and the technitian for HVAC installations. Technical specifications must be complied with, as well as documentation, time planning and cost estimate. The final project folder had to contain technical documents like circuit diagrams for electrical components, circuit diagrams for water and heating, design calculations and components lists. On the other hand construction schedule, construction implementation plan, documentation of the construction progress and minutes of meetings between the various trades had to be submitted as well. In addition to the project folder, a model of the construction project must also be created either as a handmade model or as a digital 3D-model using Computer-aided design (CAD) software. The first steps in the field of Building information modelling (BIM) had also been taken by creating a digital model of the building showing the current planning status in real time as a digital twin. This project turned out to be an excellent training of important student competencies like teamwork, communication skills, and self -organisation and also increased motivation to work on complex technical questions. The aim of giving the student a first impression on the challenges and solutions in building projects with many different technical trades and their points of view was very well achieved and should be continued in the future.},
  language  = {en}
}
@inproceedings{SchulzeBuxlohGross2021,
  author    = {Schulze-Buxloh, Lina and Groß, Rolf Fritz},
  title     = {Miniature urban farming plant: a complex educational "Toy" for engineering students},
  series = {The Future of Education 11th Edition 2021},
  booktitle = {The Future of Education 11th Edition 2021},
  pages     = {4 Seiten},
  year      = {2021},
  abstract  = {Urban farming is an innovative and sustainable way of food production and is becoming more and more important in smart city and quarter concepts. It also enables the production of certain foods in places where they usually dare not produced, such as production of fish or shrimps in large cities far away from the coast. Unfortunately, it is not always possible to show students such concepts and systems in real life as part of courses: visits of such industry plants are sometimes not possible because of distance or are permitted by the operator for hygienic reasons. In order to give the students the opportunity of getting into contact with such an urban farming system and its complex operation, an industrial urban farming plant was set up on a significantly smaller scale. Therefore, all needed technical components like water aeriation, biological and mechanical filtration or water circulation have been replaced either by aquarium components or by self-designed parts also using a 3D-printer. Students from different courses like mechanical engineering, smart building engineering, biology, electrical engineering, automation technology and civil engineering were involved in this project. This "miniature industrial plant" was also able to start operation and has now been running for two years successfully. Due to Corona pandemic, home office and remote online lectures, the automation of this miniature plant should be brought to a higher level in future for providing a good control over the system and water quality remotely. The aim of giving the student a chance to get to know the operation of an urban farming plant was very well achieved and the students had lots of fun in "playing" and learning with it in a realistic way.},
  language  = {en}
}
@inproceedings{AltherrDoeringFrauenrathetal.2024,
  author    = {Altherr, Lena and D{\"o}ring, Bernd and Frauenrath, Tobias and Groß, Rolf and Mohan, Nijanthan and Oyen, Marc and Schnittcher, Lukas and Voß, Norbert},
  title     = {DiggiTwin: ein interdisziplin{\"a}res Projekt zur Nutzung digitaler Zwillinge auf dem Weg zu einem klimaneutralen Geb{\"a}udebestand},
  series = {Tagungsband AALE 2024 : Fit f{\"u}r die Zukunft: praktische L{\"o}sungen f{\"u}r die industrielle Automation},
  booktitle = {Tagungsband AALE 2024 : Fit f{\"u}r die Zukunft: praktische L{\"o}sungen f{\"u}r die industrielle Automation},
  editor    = {Reiff-Stephan, J{\"o}rg and J{\"a}kel, Jens and Schwarz, Andr{\´e}},
  publisher = {le-tex publishing services GmbH},
  address   = {Leipzig},
  isbn      = {978-3-910103-02-3},
  doi       = {10.33968/2024.67},
  pages     = {341 -- 346},
  year      = {2024},
  abstract  = {Im Hinblick auf die Klimaziele der Bundesrepublik Deutschland konzentriert sich das Projekt Diggi Twin auf die nachhaltige Geb{\"a}udeoptimierung. Grundlage f{\"u}r eine ganzheitliche Geb{\"a}ude{\"u}berwachung und -optimierung bildet dabei die Digitalisierung und Automation im Sinne eines Smart Buildings. Das interdisziplin{\"a}re Projekt der FH Aachen hat das Ziel, ein bestehendes Hochschulgeb{\"a}ude und einen Neubau an klimaneutrale Standards anzupassen. Im Rahmen des Projekts werden bekannte Verfahren, wie das Building Information Modeling (BIM), so erweitert, dass ein digitaler Geb{\"a}udezwilling entsteht. Dieser kann zur Optimierung des Geb{\"a}udebetriebs herangezogen werden, sowie als Basis f{\"u}r eine Erweiterung des Bewertungssystems Nachhaltiges Bauen (BNB) dienen. Mithilfe von Sensortechnologie und k{\"u}nstlicher Intelligenz kann so ein pr{\"a}zises Monitoring wichtiger Geb{\"a}udedaten erfolgen, um ungenutzte Energieeinsparpotenziale zu erkennen und zu nutzen. Das Projekt erforscht und setzt methodische Erkenntnisse zu BIM und digitalen Geb{\"a}udezwillingen praxisnah um, indem es spezifische Fragen zur Energie- und Ressourceneffizienz von Geb{\"a}uden untersucht und konkrete L{\"o}sungen f{\"u}r die Geb{\"a}udeoptimierung entwickelt.},
  language  = {de}
}
@inproceedings{SchulzeBuxlohGrossUlbrich2021,
  author    = {Schulze-Buxloh, Lina and Groß, Rolf Fritz and Ulbrich, Michelle},
  title     = {Digital planning using building information modelling and virtual reality: new approach for students' remote practical training under lockdown conditions in the course of smart building engineering},
  series = {Proceedings of International Conference on Education in Mathematics, Science and Technology 2021},
  booktitle = {Proceedings of International Conference on Education in Mathematics, Science and Technology 2021},
  publisher = {ISTES Organization},
  address   = {San Antonio, TX},
  isbn      = {978-1-952092-17-6},
  pages     = {118 -- 123},
  year      = {2021},
  abstract  = {The worldwide Corona pandemic has severely restricted student projects in the higher semesters of engineering courses. In order not to delay the graduation, a new concept had to be developed for projects under lockdown conditions. Therefore, unused rooms at the university should be digitally recorded in order to develop a new usage concept as laboratory rooms. An inventory of the actual state of the rooms was done first by taking photos and listing up all flaws and peculiarities. After that, a digital site measuring was done with a 360° laser scanner and these recorded scans were linked to a coherent point cloud and transferred to a software for planning technical building services and supporting Building Information Modelling (BIM). In order to better illustrate the difference between the actual and target state, two virtual reality models were created for realistic demonstration. During the project, the students had to go through the entire digital planning phases. Technical specifications had to be complied with, as well as documentation, time planning and cost estimate. This project turned out to be an excellent alternative to on-site practical training under lockdown conditions and increased the students' motivation to deal with complex technical questions.},
  language  = {en}
}
@incollection{DuffnerUibelPetersonetal.2023,
  author    = {Duffner, Markus and Uibel, Thomas and Peterson, Leif Arne and Moorkamp, Wilfried},
  title     = {Cross Layers Light - Ein ressourceneffizientes und recyclebares Holz-Wandsystem},
  series = {Bauphysik Kalender 2023: Nachhaltigkeit},
  booktitle = {Bauphysik Kalender 2023: Nachhaltigkeit},
  editor    = {Fouad, Nabil A.},
  publisher = {Ernst \& Sohn},
  address   = {Berlin},
  isbn      = {9783433033890 (Print)},
  doi       = {10.1002/9783433611289.ch13},
  pages     = {483 -- 501},
  year      = {2023},
  abstract  = {Ein neues tragendes, lagenweise aufgebautes Holzbau-Wandsystem und seine {\"o}konomische und statische Entwicklung werden vorgestellt. Randbedingungen wie Nachhaltigkeit, Ressourceneffizienz und eine beanspruchungsadaptive Konstruktionsweise sind f{\"u}r diese innovative Bauteilentwicklung von zentraler Bedeutung. Eine wesentliche Herausforderung ist die Herstellung der Verbindung der Lagen untereinander zu einem bauphysikalisch und statisch leistungsf{\"a}higen Wandsystem. Die Tragf{\"a}higkeit und Steifigkeit verschiedener Verbindungsvarianten wurden ebenso wie die Eigenschaften der Wandelemente analytisch, numerisch und experimentell untersucht.},
  language  = {de}
}
@misc{SchulzeBuxlohGrossCheng2020,
  author    = {Schulze-Buxloh, Lina and Groß, Rolf Fritz and Cheng, Kevin Toni},
  title     = {Development and manufacturing of an interactive three-dimensional phase diagram of carbon dioxide for teaching sessions in thermodynamics},
  series = {Proceedings of the International Conference The Future of Education 2020},
  journal   = {Proceedings of the International Conference The Future of Education 2020},
  year      = {2020},
  language  = {en}
}
@inproceedings{BedburMoorkampPetersonetal.2020,
  author    = {Bedbur, Christian and Moorkamp, Wilfried and Peterson, Leif Arne and Uibel, Thomas},
  title     = {Holzbr{\"u}cken mit Natursteinbel{\"a}gen - Untersuchungen zur Aktivierung der Verbundwirkung},
  series = {Doktorandenkolloquium Holzbau Forschung + Praxis 2020},
  booktitle = {Doktorandenkolloquium Holzbau Forschung + Praxis 2020},
  editor    = {Kuhlmann, Ulrike},
  publisher = {Universit{\"a}t Stuttgart, Institut f{\"u}r Konstruktion und Entwurf},
  address   = {Stuttgart},
  pages     = {53 -- 60},
  year      = {2020},
  language  = {de}
}
@inproceedings{MohanGrossMenzeletal.2021,
  author    = {Mohan, Nijanthan and Groß, Rolf Fritz and Menzel, Karsten and Theis, Fabian},
  title     = {Opportunities and Challenges in the Implementation of Building Information Modeling for Prefabrication of Heating, Ventilation and Air Conditioning Systems in Small and Medium-Sized Contracting Companies in Germany - A Case Study},
  series = {WIT Transactions on The Built Environment, Vol. 205},
  booktitle = {WIT Transactions on The Built Environment, Vol. 205},
  publisher = {WIT Press},
  address   = {Southampton},
  issn      = {1743-3509},
  doi       = {10.2495/BIM210101},
  pages     = {117 -- 126},
  year      = {2021},
  abstract  = {Even though BIM (Building Information Modelling) is successfully implemented in most of the world, it is still in the early stages in Germany, since the stakeholders are sceptical of its reliability and efficiency. The purpose of this paper is to analyse the opportunities and obstacles to implementing BIM for prefabrication. Among all other advantages of BIM, prefabrication is chosen for this paper because it plays a vital role in creating an impact on the time and cost factors of a construction project. The project stakeholders and participants can explicitly observe the positive impact of prefabrication, which enables the breakthrough of the scepticism factor among the small-scale construction companies. The analysis consists of the development of a process workflow for implementing prefabrication in building construction followed by a practical approach, which was executed with two case studies. It was planned in such a way that, the first case study gives a first-hand experience for the workers at the site on the BIM model so that they can make much use of the created BIM model, which is a better representation compared to the traditional 2D plan. The main aim of the first case study is to create a belief in the implementation of BIM Models, which was succeeded by the execution of offshore prefabrication in the second case study. Based on the case studies, the time analysis was made and it is inferred that the implementation of BIM for prefabrication can reduce construction time, ensures minimal wastes, better accuracy, less problem-solving at the construction site. It was observed that this process requires more planning time, better communication between different disciplines, which was the major obstacle for successful implementation. This paper was carried out from the perspective of small and medium-sized mechanical contracting companies for the private building sector in Germany.},
  language  = {en}
}
@article{AngermannGuenthnerHanssenetal.2022,
  author    = {Angermann, Susanne and G{\"u}nthner, Roman and Hanssen, Henner and Lorenz, Georg and Braunisch, Matthias C. and Steubl, Dominik and Matschkal, Julia and Kemmner, Stephan and Hausinger, Renate and Block, Zenonas and Haller, Bernhard and Heemann, Uwe and Kotliar, Konstantin and Grimmer, Timo and Schmaderer, Christoph},
  title     = {Cognitive impairment and microvascular function in end-stage renal disease},
  series = {International Journal of Methods in Psychiatric Research (MPR)},
  volume    = {31},
  journal   = {International Journal of Methods in Psychiatric Research (MPR)},
  number    = {2},
  publisher = {Wiley},
  issn      = {1049-8931 (Print)},
  doi       = {10.1002/mpr.1909},
  pages     = {1 -- 10},
  year      = {2022},
  abstract  = {Objective Hemodialysis patients show an approximately threefold higher prevalence of cognitive impairment compared to the age-matched general population. Impaired microcirculatory function is one of the assumed causes. Dynamic retinal vessel analysis is a quantitative method for measuring neurovascular coupling and microvascular endothelial function. We hypothesize that cognitive impairment is associated with altered microcirculation of retinal vessels. Methods 152 chronic hemodialysis patients underwent cognitive testing using the Montreal Cognitive Assessment. Retinal microcirculation was assessed by Dynamic Retinal Vessel Analysis, which carries out an examination recording retinal vessels' reaction to a flicker light stimulus under standardized conditions. Results In unadjusted as well as in adjusted linear regression analyses a significant association between the visuospatial executive function domain score of the Montreal Cognitive Assessment and the maximum arteriolar dilation as response of retinal arterioles to the flicker light stimulation was obtained. Conclusion This is the first study determining retinal microvascular function as surrogate for cerebral microvascular function and cognition in hemodialysis patients. The relationship between impairment in executive function and reduced arteriolar reaction to flicker light stimulation supports the involvement of cerebral small vessel disease as contributing factor for the development of cognitive impairment in this patient population and might be a target for noninvasive disease monitoring and therapeutic intervention.},
  language  = {en}
}
@inproceedings{DuranParedesMottaghyHerrmannetal.2020,
  author    = {Duran Paredes, Ludwin and Mottaghy, Darius and Herrmann, Ulf and Groß, Rolf Fritz},
  title     = {Online ground temperature and soil moisture monitoring of a shallow geothermal system with non-conventional components},
  series = {EGU General Assembly 2020},
  booktitle = {EGU General Assembly 2020},
  year      = {2020},
  abstract  = {We present first results from a newly developed monitoring station for a closed loop geothermal heat pump test installation at our campus, consisting of helix coils and plate heat exchangers, as well as an ice-store system. There are more than 40 temperature sensors and several soil moisture content sensors distributed around the system, allowing a detailed monitoring under different operating conditions.In the view of the modern development of renewable energies along with the newly concepts known as Internet of Things and Industry 4.0 (high-tech strategy from the German government), we created a user-friendly web application, which will connect the things (sensors) with the open network (www). Besides other advantages, this allows a continuous remote monitoring of the data from the numerous sensors at an arbitrary sampling rate.Based on the recorded data, we will also present first results from numerical simulations, taking into account all relevant heat transport processes.The aim is to improve the understanding of these processes and their influence on the thermal behavior of shallow geothermal systems in the unsaturated zone. This will in turn facilitate the prediction of the performance of these systems and therefore yield an improvement in their dimensioning when designing a specific shallow geothermal installation.},
  language  = {en}
}
@article{KotliarOrtnerConradietal.2022,
  author    = {Kotliar, Konstantin and Ortner, Marion and Conradi, Anna and Hacker, Patricia and Hauser, Christine and G{\"u}nthner, Roman and Moser, Michaela and Muggenthaler, Claudia and Diehl-Schmid, Janine and Priller, Josef and Schmaderer, Christoph and Grimmer, Timo},
  title     = {Altered retinal cerebral vessel oscillation frequencies in Alzheimer's disease compatible with impaired amyloid clearance},
  series = {Neurobiology of Aging},
  volume    = {120},
  journal   = {Neurobiology of Aging},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0197-4580},
  doi       = {10.1016/j.neurobiolaging.2022.08.012},
  pages     = {117 -- 127},
  year      = {2022},
  abstract  = {Retinal vessels are similar to cerebral vessels in their structure and function. Moderately low oscillation frequencies of around 0.1 Hz have been reported as the driving force for paravascular drainage in gray matter in mice and are known as the frequencies of lymphatic vessels in humans. We aimed to elucidate whether retinal vessel oscillations are altered in Alzheimer's disease (AD) at the stage of dementia or mild cognitive impairment (MCI). Seventeen patients with mild-to-moderate dementia due to AD (ADD); 23 patients with MCI due to AD, and 18 cognitively healthy controls (HC) were examined using Dynamic Retinal Vessel Analyzer. Oscillatory temporal changes of retinal vessel diameters were evaluated using mathematical signal analysis. Especially at moderately low frequencies around 0.1 Hz, arterial oscillations in ADD and MCI significantly prevailed over HC oscillations and correlated with disease severity. The pronounced retinal arterial vasomotion at moderately low frequencies in the ADD and MCI groups would be compatible with the view of a compensatory upregulation of paravascular drainage in AD and strengthen the amyloid clearance hypothesis.},
  language  = {en}
}
@incollection{MoorkampPetersonUibel2022,
  author    = {Moorkamp, Wilfried and Peterson, Leif Arne and Uibel, Thomas},
  title     = {Nachhaltige Holzbr{\"u}cken f{\"u}r Geh- und Radwege},
  series = {Bauphysik Kalender 2022: Holzbau, 22. Jahrgang},
  booktitle = {Bauphysik Kalender 2022: Holzbau, 22. Jahrgang},
  editor    = {Fouad, Nabil A.},
  publisher = {Ernst \& Sohn},
  address   = {Berlin},
  isbn      = {9783433033609 (Print)},
  doi       = {10.1002/9783433611081.ch17},
  pages     = {574 -- 592},
  year      = {2022},
  abstract  = {Am Lehr- und Forschungsgebiet Holzbau der Fachhochschule Aachen wurden im Rahmen des Forschungsvorhabens „Nachhaltige Standardbr{\"u}cken in Holzbauweise" Standardtypen f{\"u}r Geh- und Radwegbr{\"u}cken entwickelt. Die Br{\"u}cken sind durch konsequente Umsetzungen von Maßnahmen des konstruktiven Holzschutzes f{\"u}r eine Nutzung von mehr als 80~Jahren konzipiert. Innovative L{\"o}sungen f{\"u}r Bauteile und Anschl{\"u}sse sowie Materialalternativen im Bereich des Belages und der Gel{\"a}nder erm{\"o}glichen eine wartungsarme Konstruktion und tragen somit zur Wirtschaftlichkeit und Nachhaltigkeit bei. Um den Einsatz der entwickelten Standardbr{\"u}ckentypen in der Praxis zu erleichtern, wurden Leistungsverzeichnisse, Musterstatiken, Musterzeichnungen und umfangreiche Detailkataloge als Unterst{\"u}tzung f{\"u}r Planer und Bauherren erstellt. Damit die Randbedingungen f{\"u}r eine lange Lebensdauer w{\"a}hrend der Nutzung der Br{\"u}cke erhalten bleiben, wurden Leitf{\"a}den f{\"u}r die Pflege und Wartung sowie f{\"u}r die Br{\"u}ckenpr{\"u}fung erarbeitet. Der Beitrag gibt Einblicke in das Forschungsvorhaben und seine Resultate.},
  language  = {de}
}
@article{NeumaierWeissVeldemanetal.2021,
  author    = {Neumaier, Felix and Weiss, Miriam and Veldeman, Michael and Kotliar, Konstantin and Wiesmann, Martin and Schulze-Steinen, Henna and H{\"o}llig, Anke and Clusmann, Hans and Schubert, Gerrit Alexander and Albanna, Walid},
  title     = {Changes in endogenous daytime melatonin levels after aneurysmal subarachnoid hemorrhage - preliminary findings from an observational cohort study},
  series = {Clinical Neurology and Neurosurgery},
  volume    = {208},
  journal   = {Clinical Neurology and Neurosurgery},
  number    = {Article No.: 106870},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0303-8467},
  doi       = {10.1016/j.clineuro.2021.106870},
  year      = {2021},
  abstract  = {Aneurysmal subarachnoid hemorrhage (aSAH) is associated with early and delayed brain injury due to several underlying and interrelated processes, which include inflammation, oxidative stress, endothelial, and neuronal apoptosis. Treatment with melatonin, a cytoprotective neurohormone with anti-inflammatory, anti-oxidant and anti-apoptotic effects, has been shown to attenuate early brain injury (EBI) and to prevent delayed cerebral vasospasm in experimental aSAH models. Less is known about the role of endogenous melatonin for aSAH outcome and how its production is altered by the pathophysiological cascades initiated during EBI. In the present observational study, we analyzed changes in melatonin levels during the first three weeks after aSAH.},
  language  = {en}
}
@incollection{MoorkampPetersonUibel2023,
  author    = {Moorkamp, Wilfried and Peterson, Leif Arne and Uibel, Thomas},
  title     = {Standardholzbr{\"u}cken f{\"u}r kommunale Geh- und Radwege},
  series = {Strukturen, Formen und Prinzipien : Festschrift zum 60. Geburtstag von Univ.-Prof. Dr.-Ing. Martin Trautz},
  booktitle = {Strukturen, Formen und Prinzipien : Festschrift zum 60. Geburtstag von Univ.-Prof. Dr.-Ing. Martin Trautz},
  editor    = {Wehren, Cedric},
  publisher = {RWTH Aachen},
  address   = {Aachen},
  isbn      = {978-3-95886-500-6},
  pages     = {140 -- 165},
  year      = {2023},
  language  = {de}
}
@book{UibelPeterson2023,
  author    = {Uibel, Thomas and Peterson, Leif Arne},
  title     = {Tagungsband Aachener Holzbautagung 2023},
  editor    = {Uibel, Thomas and Peterson, Leif Arne},
  publisher = {FH Aachen},
  address   = {Aachen},
  issn      = {2197-4489},
  year      = {2023},
  language  = {de}
}
@article{AlnemerKotliarNeuhausetal.2023,
  author    = {Alnemer, Momin Sami Mohammad and Kotliar, Konstantin and Neuhaus, Valentin and Pape, Hans-Christoph and Ciritsis, Bernhard D.},
  title     = {Cost-effectiveness analysis of surgical proximal femur fracture prevention in elderly: a Markov cohort simulation model},
  series = {Cost Effectiveness and Resource Allocation},
  journal   = {Cost Effectiveness and Resource Allocation},
  number    = {21, Article number: 77},
  publisher = {Springer Nature},
  issn      = {1478-7547},
  doi       = {10.1186/s12962-023-00482-4},
  pages     = {12 Seiten},
  year      = {2023},
  abstract  = {Background Hip fractures are a common and costly health problem, resulting in significant morbidity and mortality, as well as high costs for healthcare systems, especially for the elderly. Implementing surgical preventive strategies has the potential to improve the quality of life and reduce the burden on healthcare resources, particularly in the long term. However, there are currently limited guidelines for standardizing hip fracture prophylaxis practices. Methods This study used a cost-effectiveness analysis with a finite-state Markov model and cohort simulation to evaluate the primary and secondary surgical prevention of hip fractures in the elderly. Patients aged 60 to 90 years were simulated in two different models (A and B) to assess prevention at different levels. Model A assumed prophylaxis was performed during the fracture operation on the contralateral side, while Model B included individuals with high fracture risk factors. Costs were obtained from the Centers for Medicare \& Medicaid Services, and transition probabilities and health state utilities were derived from available literature. The baseline assumption was a 10\% reduction in fracture risk after prophylaxis. A sensitivity analysis was also conducted to assess the reliability and variability of the results. Results With a 10\% fracture risk reduction, model A costs between \$8,850 and \$46,940 per quality-adjusted life-year (\$/QALY). Additionally, it proved most cost-effective in the age range between 61 and 81 years. The sensitivity analysis established that a reduction of ≥ 2.8\% is needed for prophylaxis to be definitely cost-effective. The cost-effectiveness at the secondary prevention level was most sensitive to the cost of the contralateral side's prophylaxis, the patient's age, and fracture treatment cost. For high-risk patients with no fracture history, the cost-effectiveness of a preventive strategy depends on their risk profile. In the baseline analysis, the incremental cost-effectiveness ratio at the primary prevention level varied between \$11,000/QALY and \$74,000/QALY, which is below the defined willingness to pay threshold. Conclusion Due to the high cost of hip fracture treatment and its increased morbidity, surgical prophylaxis strategies have demonstrated that they can significantly relieve the healthcare system. Various key assumptions facilitated the modeling, allowing for adequate room for uncertainty. Further research is needed to evaluate health-state-associated risks.},
  language  = {en}
}
@article{KuchlerGuenthnerRibeiroetal.2023,
  author    = {Kuchler, Timon and G{\"u}nthner, Roman and Ribeiro, Andrea and Hausinger, Renate and Streese, Lukas and W{\"o}hnl, Anna and Kesseler, Veronika and Negele, Johanna and Assali, Tarek and Carbajo-Lozoya, Javier and Lech, Maciej and Adorjan, Kristina and Stubbe, Hans Christian and Hanssen, Henner and Kotliar, Konstantin and Haller, Berhard and Heemann, Uwe and Schmaderer, Christoph},
  title     = {Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation},
  volume    = {26},
  publisher = {Springer Nature},
  address   = {Dordrecht},
  doi       = {10.1007/s10456-023-09885-6},
  pages     = {547 -- 563},
  year      = {2023},
  abstract  = {Background Post-COVID-19 syndrome (PCS) is a lingering disease with ongoing symptoms such as fatigue and cognitive impairment resulting in a high impact on the daily life of patients. Understanding the pathophysiology of PCS is a public health priority, as it still poses a diagnostic and treatment challenge for physicians. Methods In this prospective observational cohort study, we analyzed the retinal microcirculation using Retinal Vessel Analysis (RVA) in a cohort of patients with PCS and compared it to an age- and gender-matched healthy cohort (n = 41, matched out of n = 204). Measurements and main results PCS patients exhibit persistent endothelial dysfunction (ED), as indicated by significantly lower venular flicker-induced dilation (vFID; 3.42\% ± 1.77\% vs. 4.64\% ± 2.59\%; p = 0.02), narrower central retinal artery equivalent (CRAE; 178.1 [167.5-190.2] vs. 189.1 [179.4-197.2], p = 0.01) and lower arteriolar-venular ratio (AVR; (0.84 [0.8-0.9] vs. 0.88 [0.8-0.9], p = 0.007). When combining AVR and vFID, predicted scores reached good ability to discriminate groups (area under the curve: 0.75). Higher PCS severity scores correlated with lower AVR (R = - 0.37 p = 0.017). The association of microvascular changes with PCS severity were amplified in PCS patients exhibiting higher levels of inflammatory parameters. Conclusion Our results demonstrate that prolonged endothelial dysfunction is a hallmark of PCS, and impairments of the microcirculation seem to explain ongoing symptoms in patients. As potential therapies for PCS emerge, RVA parameters may become relevant as clinical biomarkers for diagnosis and therapy management.},
  language  = {en}
}
@article{KuertenKotliarFuestetal.2021,
  author    = {Kuerten, David and Kotliar, Konstantin and Fuest, Matthias and Walter, Peter and Hollstein, Muriel and Plange, Niklas},
  title     = {Does hemispheric vascular regulation differ significantly in glaucoma patients with altitudinal visual field asymmetry? A single-center, prospective study},
  series = {International Ophthalmology},
  volume    = {41},
  journal   = {International Ophthalmology},
  number    = {41},
  editor    = {Neri, Piergiorgio},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {1573-2630},
  doi       = {10.1007/s10792-021-01876-0},
  pages     = {3109 -- 3119},
  year      = {2021},
  abstract  = {Purpose Vascular risk factors and ocular perfusion are heatedly discussed in the pathogenesis of glaucoma. The retinal vessel analyzer (RVA, IMEDOS Systems, Germany) allows noninvasive measurement of retinal vessel regulation. Significant differences especially in the veins between healthy subjects and patients suffering from glaucoma were previously reported. In this pilot-study we investigated if localized vascular regulation is altered in glaucoma patients with altitudinal visual field defect asymmetry. Methods 15 eyes of 12 glaucoma patients with advanced altitudinal visual field defect asymmetry were included. The mean defect was calculated for each hemisphere separately (-20.99 ± 10.49 pro- found hemispheric visual field defect vs -7.36 ± 3.97 dB less profound hemisphere). After pupil dilation, RVA measurements of retinal arteries and veins were conducted using the standard protocol. The superior and inferior retinal vessel reactivity were measured consecutively in each eye. Results Significant differences were recorded in venous vessel constriction after flicker light stimulation and overall amplitude of the reaction (p \ 0.04 and p \ 0.02 respectively) in-between the hemispheres spheres. Vessel reaction was higher in the hemisphere corresponding to the more advanced visual field defect. Arterial diameters reacted similarly, failing to reach statistical significance. Conclusion Localized retinal vessel regulation is significantly altered in glaucoma patients with asymmetri altitudinal visual field defects. Veins supplying the hemisphere concordant to a less profound visual field defect show diminished diameter changes. Vascular dysregulation might be particularly important in early glaucoma stages prior to a significant visual field defect.},
  language  = {en}
}
@article{AlbannaConzenWeissetal.2021,
  author    = {Albanna, Walid and Conzen, Catharina and Weiss, Miriam and Seyfried, Katharina and Kotliar, Konstantin and Schmidt, Tobias Philip and Kuerten, David and Hescheler, J{\"u}rgen and Bruecken, Anne and Schmidt-Trucks{\"a}ss, Arno and Neumaier, Felix and Wiesmann, Martin and Clusmann, Hans and Schubert, Gerrit Alexander},
  title     = {Non-invasive assessment of neurovascular coupling after aneurysmal subarachnoid hemorrhage: a prospective observational trial using retinal vessel analysis},
  series = {Frontiers in Neurology},
  volume    = {12},
  journal   = {Frontiers in Neurology},
  number    = {12},
  issn      = {1664-2295},
  doi       = {10.3389/fneur.2021.690183},
  pages     = {1 -- 15},
  year      = {2021},
  abstract  = {Delayed cerebral ischemia (DCI) is a common complication after aneurysmal subarachnoid hemorrhage (aSAH) and can lead to infarction and poor clinical outcome. The underlying mechanisms are still incompletely understood, but animal models indicate that vasoactive metabolites and inflammatory cytokines produced within the subarachnoid space may progressively impair and partially invert neurovascular coupling (NVC) in the brain. Because cerebral and retinal microvasculature are governed by comparable regulatory mechanisms and may be connected by perivascular pathways, retinal vascular changes are increasingly recognized as a potential surrogate for altered NVC in the brain. Here, we used non-invasive retinal vessel analysis (RVA) to assess microvascular function in aSAH patients at different times after the ictus.},
  language  = {en}
}
@incollection{Kotliar2021,
  author    = {Kotliar, Konstantin},
  title     = {Ocular rigidity: clinical approach},
  series = {Ocular Rigidity, Biomechanics and Hydrodynamics of the Eye},
  booktitle = {Ocular Rigidity, Biomechanics and Hydrodynamics of the Eye},
  editor    = {Pallikaris, I. and Tsilimbaris, M. K. and Dastiridou, A. I.},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-64422-2},
  doi       = {10.1007/978-3-030-64422-2_2},
  pages     = {15 -- 43},
  year      = {2021},
  abstract  = {The term ocular rigidity is widely used in clinical ophthalmology. Generally it is assumed as a resistance of the whole eyeball to mechanical deformation and relates to biomechanical properties of the eye and its tissues. Basic principles and formulas for clinical tonometry, tonography and pulsatile ocular blood flow measurements are based on the concept of ocular rigidity. There is evidence for altered ocular rigidity in aging, in several eye diseases and after eye surgery. Unfortunately, there is no consensual view on ocular rigidity: it used to make a quite different sense for different people but still the same name. Foremost there is no clear consent between biomechanical engineers and ophthalmologists on the concept. Moreover ocular rigidity is occasionally characterized using various parameters with their different physical dimensions. In contrast to engineering approach, clinical approach to ocular rigidity claims to characterize the total mechanical response of the eyeball to its deformation without any detailed considerations on eye morphology or material properties of its tissues. Further to the previous chapter this section aims to describe clinical approach to ocular rigidity from the perspective of an engineer in an attempt to straighten out this concept, to show its advantages, disadvantages and various applications.},
  language  = {en}
}
@inproceedings{IomdinaKiselevaKotliaretal.2020,
  author    = {Iomdina, Elena N. and Kiseleva, Anna A. and Kotliar, Konstantin and Luzhnov, Petr V.},
  title     = {Quantification of Choroidal Blood Flow Using the OCT-A System Based on Voxel Scan Processing},
  series = {Proceedings of the International Conference on Biomedical Innovations and Applications- BIA 2020},
  booktitle = {Proceedings of the International Conference on Biomedical Innovations and Applications- BIA 2020},
  publisher = {IEEE},
  address   = {New York, NY},
  isbn      = {978-1-7281-7073-2},
  doi       = {10.1109/BIA50171.2020.9244511},
  pages     = {41 -- 44},
  year      = {2020},
  abstract  = {The paper presents a method for the quantitative assessment of choroidal blood flow using an OCT-A system. The developed technique for processing of OCT-A scans is divided into two stages. At the first stage, the identification of the boundaries in the selected portion was performed. At the second stage, each pixel mark on the selected layer was represented as a volume unit, a voxel, which characterizes the region of moving blood. Three geometric shapes were considered to represent the voxel. On the example of one OCT-A scan, this work presents a quantitative assessment of the blood flow index. A possible modification of two-stage algorithm based on voxel scan processing is presented.},
  language  = {en}
}
@article{WerfelGuenthnerHapfelmeieretal.2022,
  author    = {Werfel, Stanislas and G{\"u}nthner, Roman and Hapfelmeier, Alexander and Hanssen, Henner and Kotliar, Konstantin and Heemann, Uwe and Schmaderer, Christoph},
  title     = {Identification of cardiovascular high-risk groups from dynamic retinal vessel signals using untargeted machine learning},
  series = {Cardiovascular Research},
  volume    = {118},
  journal   = {Cardiovascular Research},
  number    = {2},
  editor    = {Guzik, Tomasz J.},
  publisher = {Oxford University Press},
  address   = {Oxford},
  issn      = {0008-6363},
  doi       = {10.1093/cvr/cvab040},
  pages     = {612 -- 621},
  year      = {2022},
  abstract  = {Dynamic retinal vessel analysis (DVA) provides a non-invasive way to assess microvascular function in patients and potentially to improve predictions of individual cardiovascular (CV) risk. The aim of our study was to use untargeted machine learning on DVA in order to improve CV mortality prediction and identify corresponding response alterations.},
  language  = {en}
}
@article{MalanHamerKaeneletal.2020,
  author    = {Malan, Leone and Hamer, Mark and K{\"a}nel, Roland von and Kotliar, Konstantin and Wyk, Roelof D. van and Lambert, Gavin W. and Vilser, Walthard and Ziemssen, Tjalf and Schlaich, Markus P. and Smith, Wayne and Magnusson, Martin and Wentzel, Annemarie and Myburgh, Carlien E. and Steyn, Hendrik S. and Malan, Nico T.},
  title     = {Delayed retinal vein recovery responses indicate both non-adaptation to stress as well as increased risk for stroke: the SABPA study},
  series = {Cardiovascular Journal of Africa},
  volume    = {26},
  journal   = {Cardiovascular Journal of Africa},
  number    = {31},
  publisher = {Clinics Cardive Publishing},
  address   = {Durbanville},
  issn      = {1680-0745},
  doi       = {10.5830/CVJA-2020-031},
  pages     = {1 -- 12},
  year      = {2020},
  language  = {en}
}
@article{StreeseKotliarDeiserothetal.2020,
  author    = {Streese, Lukas and Kotliar, Konstantin and Deiseroth, Arne and Infanger, Denis and Gugleta, Konstantin and Schmaderer, Christoph and Hanssen, Henner},
  title     = {Retinal endothelial function in cardiovascular risk patients: A randomized controlled exercise trial},
  series = {Scandinavian Journal of Medicine and Science in Sports},
  volume    = {30},
  journal   = {Scandinavian Journal of Medicine and Science in Sports},
  number    = {2},
  publisher = {Wiley},
  address   = {Oxford},
  issn      = {1600-0838},
  doi       = {10.1111/sms.13560},
  pages     = {272 -- 280},
  year      = {2020},
  abstract  = {The aim of this study was to investigate, for the first time, the effects of high-intensity interval training (HIIT) on retinal microvascular endothelial function in cardiovascular (CV) risk patients. In the randomized controlled trial, middle-aged and previously sedentary patients with increased CV risk (aged 58 ± 6 years) with ≥ two CV risk factors were randomized into a 12-week HIIT (n = 33) or control group (CG, n = 36) with standard physical activity recommendations. A blinded examiner measured retinal endothelial function by flicker light-induced maximal arteriolar (ADmax) and venular (VDmax) dilatation as well as the area under the arteriolar (AFarea) and venular (VFarea) flicker curve using a retinal vessel analyzer. Standardized assessments of CV risk factors, cardiorespiratory fitness, and retinal endothelial function were performed before and after HIIT. HIIT reduced body mass index, fat mass, and low-density lipoprotein and increased muscle mass and peak oxygen uptake (VO2peak). Both ADmax (pre: 2.7 ± 2.1\%, post: 3.0 ± 2.2\%, P = .018) and AFarea (pre: 32.6 ± 28.4\%*s, post: 37.7 ± 30.6\%*s, P = .016) increased after HIIT compared with CG (ADmax, pre: 3.2 ± 1.8\%, post: 2.9 ± 1.8\%, P = .254; AFarea, pre: 41.6 ± 28.5\%*s, post: 37.8 ± 27.0\%*s, P = .186). Venular function remained unchanged after HIIT. There was a significant association between ∆-change VO2peak and ∆-changes ADmax and AFarea (P = .026, R² = 0.073; P = .019, R² = 0.081, respectively). 12-weeks of HIIT improved retinal endothelial function in middle-aged patients with increased CV risk independent of the reduction in classical CV risk factors. Exercise has the potential to reverse or at least postpone progression of small vessel disease in older adults with increased CV risk under standard medication. Dynamic retinal vessel analysis seems to be a sensitive tool to detect treatment effects of exercise interventions on retinal microvascular endothelial function in middle-aged individuals with increased CV risk.},
  language  = {en}
}
@article{HamouKotliarTanetal.2020,
  author    = {Hamou, Hussam Aldin and Kotliar, Konstantin and Tan, Sonny Kian and Weiß, Christel and Blume, Christian and Clusmann, Hans and Schubert, Gerrit Alexander and Albanna, Walid},
  title     = {Surgical nuances and placement of subgaleal drains for supratentorial procedures—a prospective analysis of efficacy and outcome in 150 craniotomies},
  series = {Acta Neurochirurgica},
  volume    = {2020},
  journal   = {Acta Neurochirurgica},
  number    = {162},
  publisher = {Springer Nature},
  address   = {Cham},
  issn      = {0942-0940},
  doi       = {10.1007/s00701-019-04196-6},
  pages     = {729 -- 736},
  year      = {2020},
  abstract  = {Background For supratentorial craniotomy, surgical access, and closure technique, including placement of subgaleal drains, may vary considerably. The influence of surgical nuances on postoperative complications such as cerebrospinal fluid leakage or impaired wound healing overall remains largely unclear. With this study, we are reporting our experiences and the impact of our clinical routines on outcome in a prospectively collected data set. Method We prospectively observed 150 consecutive patients undergoing supratentorial craniotomy and recorded technical variables (type/length of incision, size of craniotomy, technique of dural and skin closure, type of dressing, and placement of subgaleal drains). Outcome variables (subgaleal hematoma/CSF collection, periorbital edema, impairment of wound healing, infection, and need for operative revision) were recorded at time of discharge and at late follow-up. Results Early subgaleal fluid collection was observed in 36.7\% (2.8\% at the late follow-up), and impaired wound healing was recorded in 3.3\% of all cases, with an overall need for operative revision of 6.7\%. Neither usage of dural sealants, lack of watertight dural closure, and presence of subgaleal drains, nor type of skin closure or dressing influenced outcome. Curved incisions, larger craniotomy, and tumor size, however, were associated with an increase in early CSF or hematoma collection (p < 0.0001, p = 0.001, p < 0.01 resp.), and larger craniotomy size was associated with longer persistence of subgaleal fluid collections (p < 0.05). Conclusions Based on our setting, individual surgical nuances such as the type of dural closure and the use of subgaleal drains resulted in a comparable complication rate and outcome. Subgaleal fluid collections were frequently observed after supratentorial procedures, irrespective of the closing technique employed, and resolve spontaneously in the majority of cases without significant sequelae. Our results are limited due to the observational nature in our single-center study and need to be validated by supportive prospective randomized design.},
  language  = {en}
}
@article{RamoshabaHuismanLammertynetal.2020,
  author    = {Ramoshaba, Nthai E. and Huisman, Hugo W. and Lammertyn, Leandi and Kotliar, Konstantin and Schutte, Aletta E. and Smith, Wayne},
  title     = {Retinal microvasculature and masked hypertension in young adults: the African-PREDICT study},
  series = {Hypertension Research},
  journal   = {Hypertension Research},
  number    = {43},
  publisher = {Springer Nature},
  address   = {Osaka},
  issn      = {1348-4214},
  doi       = {10.1038/s41440-020-0487-0},
  pages     = {1231 -- 1238},
  year      = {2020},
  abstract  = {Masked hypertension is known to induce microvascular complications. However, it is unclear whether early microvascular changes are already occurring in young, otherwise healthy adults. We therefore investigated whether retinal microvascular calibers and acute responses to a flicker stimulus are related to masked hypertension. We used the baseline data of 889 participants aged 20-30 years who were taking part in the African Prospective study on the Early Detection and Identification of Cardiovascular Disease and Hypertension. Clinic and 24-h ambulatory blood pressure were measured. The central retinal artery equivalent (CRAE) and central retinal vein equivalent were calculated from fundus images, and retinal vessel dilation was determined in response to flicker light-induced provocation. A smaller CRAE was observed in those with masked hypertension vs. those with normotension (157.1 vs. 161.2 measuring units, P < 0.001). In forward multivariable-adjusted regression analysis, only CRAE was negatively related to masked hypertension [adjusted R² = 0.267, β = -0.097 (95\% CI = -0.165; -0.029), P = 0.005], but other retinal microvascular parameters were not associated with masked hypertension. In multivariable logistic regression analyses, masked hypertension [OR = 2.333, (95\% CI = 1.316; 4.241), P = 0.004] was associated with a narrower CRAE. In young healthy adults, masked hypertension was associated with retinal arteriolar narrowing, thereby reflecting early microvascular alterations known to predict cardiovascular outcomes in later life.},
  language  = {en}
}
@article{SmithKotliarLammertynetal.2020,
  author    = {Smith, Wayne and Kotliar, Konstantin and Lammertyn, Leandi and Ramoshaba, Nthai E. and Vilser, Walthard and Huisman, Hugo W. and Schutte, Aletta E.},
  title     = {Retinal vessel caliber and caliber responses in true normotensive black and white adults: The African-PREDICT study},
  series = {Microvascular Research},
  volume    = {128},
  journal   = {Microvascular Research},
  number    = {Article 103937},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0026-2862},
  doi       = {10.1016/j.mvr.2019.103937},
  year      = {2020},
  abstract  = {Purpose Globally, a detrimental shift in cardiovascular disease risk factors and a higher mortality level are reported in some black populations. The retinal microvasculature provides early insight into the pathogenesis of systemic vascular diseases, but it is unclear whether retinal vessel calibers and acute retinal vessel functional responses differ between young healthy black and white adults. Methods We included 112 black and 143 white healthy normotensive adults (20-30 years). Retinal vessel calibers (central retinal artery and vein equivalent (CRAE and CRVE)) were calculated from retinal images and vessel caliber responses to flicker light induced provocation (FLIP) were determined. Additionally, ambulatory blood pressure (BP), anthropometry and blood samples were collected. Results The groups displayed similar 24 h BP profiles and anthropometry (all p > .24). Black participants demonstrated a smaller CRAE (158 ± 11 vs. 164 ± 11 MU, p < .001) compared to the white group, whereas CRVE was similar (p = .57). In response to FLIP, artery maximal dilation was greater in the black vs. white group (5.6 ± 2.1 vs. 3.3 ± 1.8\%; p < .001). Conclusions Already at a young age, healthy black adults showed narrower retinal arteries relative to the white population. Follow-up studies are underway to show if this will be related to increased risk for hypertension development. The reason for the larger vessel dilation responses to FLIP in the black population is unclear and warrants further investigation.},
  language  = {en}
}
@article{FayyaziSardarThomasetal.2023,
  author    = {Fayyazi, Mojgan and Sardar, Paramjotsingh and Thomas, Sumit Infent and Daghigh, Roonak and Jamali, Ali and Esch, Thomas and Kemper, Hans and Langari, Reza and Khayyam, Hamid},
  title     = {Artificial intelligence/machine learning in energy management systems, control, and optimization of hydrogen fuel cell vehicles},
  volume    = {15},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  doi       = {10.3390/su15065249},
  pages     = {38},
  year      = {2023},
  abstract  = {Environmental emissions, global warming, and energy-related concerns have accelerated the advancements in conventional vehicles that primarily use internal combustion engines. Among the existing technologies, hydrogen fuel cell electric vehicles and fuel cell hybrid electric vehicles may have minimal contributions to greenhouse gas emissions and thus are the prime choices for environmental concerns. However, energy management in fuel cell electric vehicles and fuel cell hybrid electric vehicles is a major challenge. Appropriate control strategies should be used for effective energy management in these vehicles. On the other hand, there has been significant progress in artificial intelligence, machine learning, and designing data-driven intelligent controllers. These techniques have found much attention within the community, and state-of-the-art energy management technologies have been developed based on them. This manuscript reviews the application of machine learning and intelligent controllers for prediction, control, energy management, and vehicle to everything (V2X) in hydrogen fuel cell vehicles. The effectiveness of data-driven control and optimization systems are investigated to evolve, classify, and compare, and future trends and directions for sustainability are discussed.},
  language  = {en}
}
@inproceedings{VeettilRakshitSchopenetal.2022,
  author    = {Veettil, Yadu Krishna Morassery and Rakshit, Shantam and Schopen, Oliver and Kemper, Hans and Esch, Thomas and Shabani, Bahman},
  title     = {Automated Control System Strategies to Ensure Safety of PEM Fuel Cells Using Kalman Filters},
  series = {Proceedings of the 7th International Conference and Exhibition on Sustainable Energy and Advanced Materials (ICE-SEAM 2021), Melaka, Malaysia},
  booktitle = {Proceedings of the 7th International Conference and Exhibition on Sustainable Energy and Advanced Materials (ICE-SEAM 2021), Melaka, Malaysia},
  editor    = {Bin Abdollah, Mohd Fadzli and Amiruddin, Hilmi and Singh, Amrik Singh Phuman and Munir, Fudhail Abdul and Ibrahim, Asriana},
  publisher = {Springer Nature},
  address   = {Singapore},
  isbn      = {978-981-19-3178-9},
  issn      = {2195-4356},
  doi       = {10.1007/978-981-19-3179-6_55},
  pages     = {296 -- 299},
  year      = {2022},
  abstract  = {Having well-defined control strategies for fuel cells, that can efficiently detect errors and take corrective action is critically important for safety in all applications, and especially so in aviation. The algorithms not only ensure operator safety by monitoring the fuel cell and connected components, but also contribute to extending the health of the fuel cell, its durability and safe operation over its lifetime. While sensors are used to provide peripheral data surrounding the fuel cell, the internal states of the fuel cell cannot be directly measured. To overcome this restriction, Kalman Filter has been implemented as an internal state observer. Other safety conditions are evaluated using real-time data from every connected sensor and corrective actions automatically take place to ensure safety. The algorithms discussed in this paper have been validated thorough Model-in-the-Loop (MiL) tests as well as practical validation at a dedicated test bench.},
  language  = {en}
}
@article{FissabreRottke2023,
  author    = {Fissabre, Anke and Rottke, Evelin},
  title     = {Das Quelle-Fertighaus : Einklang von Maß, Konstruktion und Entwurf},
  series = {architectura},
  volume    = {51},
  journal   = {architectura},
  number    = {1},
  editor    = {Bergdoll, Barry and Schwarting, Andreas and Tragbar, Klaus},
  publisher = {Deutscher Kunstverlag (DKV)},
  address   = {Berlin},
  issn      = {2569-1554},
  doi       = {10.1515/atc-2021-1005},
  pages     = {57 -- 78},
  year      = {2023},
  abstract  = {The steel prefabricated family house ›Quelle-Fertighaus‹ designed and constructed by the German company Quelle, is an innovative modular system commercialised in 1962. All aspects of the Quelle-Fertighaus are planned on the principle of minimal effort for maximal flexibility. The clever design of the ground plan based on a 4 m × 7 m module offers the flexibility for either one to three additional modules. The steel construction is innovative and unique, consisting of load-bearing portal frames acting as braces. The house design is furthermore characterised by a simple metrical grid layout and the practical placement of the foundation and basement, which allowed the very cost-effective production and the lowest price for a prefabricated family house in Germany during the postwar era. Nowadays its portal-frame-construction offers an interesting approach for its renovation and transformation according to present building demands.},
  language  = {de}
}
@article{NeumaierKotliarHaerenetal.2021,
  author    = {Neumaier, Felix and Kotliar, Konstantin and Haeren, Roel Hubert Louis and Temel, Yasin and L{\"u}ke, Jan Niklas and Seyam, Osama and Lindauer, Ute and Clusmann, Hans and Hescheler, J{\"u}rgen and Schubert, Gerrit Alexander and Schneider, Toni and Albanna, Walid},
  title     = {Retinal Vessel Responses to Flicker Stimulation Are Impaired in Ca v 2.3-Deficient Mice—An in- vivo Evaluation Using Retinal Vessel Analysis (RVA)},
  series = {Frontiers in Neurology},
  volume    = {12},
  journal   = {Frontiers in Neurology},
  publisher = {Frontiers},
  doi       = {10.3389/fneur.2021.659890},
  pages     = {1 -- 11},
  year      = {2021},
  language  = {en}
}
@inproceedings{SattlerAttiAlexopoulosetal.2022,
  author    = {Sattler, Johannes Christoph and Atti, Vikrama and Alexopoulos, Spiros and Teixeira Boura, Cristiano Jos{\´e} and Herrmann, Ulf and Dutta, Siddharth and Kioutsioukis, Ioannis},
  title     = {DNI forecast tool for the smart operation of a parabolic trough collector system with concrete thermal energy storage: Theory, results and outlook},
  series = {SolarPACES 2022 conference proceedings},
  booktitle = {SolarPACES 2022 conference proceedings},
  number    = {1},
  publisher = {TIB Open Publishing},
  address   = {Hannover},
  issn      = {2751-9899 (online)},
  doi       = {10.52825/solarpaces.v1i.731},
  pages     = {9 Seiten},
  year      = {2022},
  abstract  = {This work presents a basic forecast tool for predicting direct normal irradiance (DNI) in hourly resolution, which the Solar-Institut J{\"u}lich (SIJ) is developing within a research project. The DNI forecast data shall be used for a parabolic trough collector (PTC) system with a concrete thermal energy storage (C-TES) located at the company KEAN Soft Drinks Ltd in Limassol, Cyprus. On a daily basis, 24-hour DNI prediction data in hourly resolution shall be automatically produced using free or very low-cost weather forecast data as input. The purpose of the DNI forecast tool is to automatically transfer the DNI forecast data on a daily basis to a main control unit (MCU). The MCU automatically makes a smart decision on the operation mode of the PTC system such as steam production mode and/or C-TES charging mode. The DNI forecast tool was evaluated using historical data of measured DNI from an on-site weather station, which was compared to the DNI forecast data. The DNI forecast tool was tested using data from 56 days between January and March 2022, which included days with a strong variation in DNI due to cloud passages. For the evaluation of the DNI forecast reliability, three categories were created and the forecast data was sorted accordingly. The result was that the DNI forecast tool has a reliability of 71.4 \% based on the tested days. The result fulfils SIJ's aim to achieve a reliability of around 70 \%, but SIJ aims to still improve the DNI forecast quality.},
  language  = {en}
}
@inproceedings{SchopenKemperEsch2021,
  author    = {Schopen, Oliver and Kemper, Hans and Esch, Thomas},
  title     = {Development of a comparison methodology and evaluation matrix for electrically driven compressors in ICE and FC},
  series = {Proceedings of the 1st UNITED - Southeast Asia Automotive Interest Group (SAIG) International Conference},
  booktitle = {Proceedings of the 1st UNITED - Southeast Asia Automotive Interest Group (SAIG) International Conference},
  publisher = {FH Joanneum},
  address   = {Graz},
  isbn      = {978-3-902103-94-9},
  pages     = {45 -- 46},
  year      = {2021},
  abstract  = {In addition to electromobility and alternative drive systems, a focus is set on electrically driven compressors (EDC), with a high potential for increasing the efficiency of internal combustion engines (ICE) and fuel cells [01]. The primary objective is to increase the ICE torque, provided independently of the ICE speed by compressing the intake air and consequently the ICE filling level supported by the compressor. For operation independent from the ICE speed, the EDC compressor is decoupled from the turbine by using an electric compressor motor (CM) instead of the turbine. ICE performances can be increased by the use of EDC where individual compressor parameters are adapted to the respective application area [02] [03]. This task contains great challenges, increased by demands with regard to pollutant reduction while maintaining constant performance and reduced fuel consumption. The FH-Aachen is equipped with an EDC test bench which enables EDC-investigations in various configurations and operating modes. Characteristic properties of different compressors can be determined, which build the basis for a comparison methodology. Subject of this project is the development of a comparison methodology for EDC with an associated evaluation method and a defined overall evaluation method. For the application of this comparison methodology, corresponding series of measurements are carried out on the EDC test bench using an appropriate test device.},
  language  = {en}
}
@incollection{HoffschmidtAlexopoulosRauetal.2022,
  author    = {Hoffschmidt, Bernhard and Alexopoulos, Spiros and Rau, Christoph and Sattler, Johannes, Christoph and Anthrakidis, Anette and Teixeira Boura, Cristiano Jos{\´e} and O'Connor, B. and Chico Caminos, R.A. and Rend{\´o}n, C. and Hilger, P.},
  title     = {Concentrating solar power},
  series = {Comprehensive Renewable Energy (Second Edition) / Volume 3: Solar Thermal Systems: Components and Applications},
  booktitle = {Comprehensive Renewable Energy (Second Edition) / Volume 3: Solar Thermal Systems: Components and Applications},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {978-0-12-819734-9},
  pages     = {670 -- 724},
  year      = {2022},
  abstract  = {The focus of this chapter is the production of power and the use of the heat produced from concentrated solar thermal power (CSP) systems. The chapter starts with the general theoretical principles of concentrating systems including the description of the concentration ratio, the energy and mass balance. The power conversion systems is the main part where solar-only operation and the increase in operational hours. Solar-only operation include the use of steam turbines, gas turbines, organic Rankine cycles and solar dishes. The operational hours can be increased with hybridization and with storage. Another important topic is the cogeneration where solar cooling, desalination and of heat usage is described. Many examples of commercial CSP power plants as well as research facilities from the past as well as current installed and in operation are described in detail. The chapter closes with economic and environmental aspects and with the future potential of the development of CSP around the world.},
  language  = {en}
}
@incollection{HoffschmidtAlexopoulosRauetal.2021,
  author    = {Hoffschmidt, Bernhard and Alexopoulos, Spiros and Rau, Christoph and Sattler, Johannes, Christoph and Anthrakidis, Anette and Teixeira Boura, Cristiano Jos{\´e} and O'Connor, B. and Caminos, R.A. Chico and Rend{\´o}n, C. and Hilger, P.},
  title     = {Concentrating Solar Power},
  series = {Earth systems and environmental sciences},
  booktitle = {Earth systems and environmental sciences},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {978-0-12-409548-9},
  doi       = {10.1016/B978-0-12-819727-1.00089-3},
  year      = {2021},
  abstract  = {The focus of this chapter is the production of power and the use of the heat produced from concentrated solar thermal power (CSP) systems. The chapter starts with the general theoretical principles of concentrating systems including the description of the concentration ratio, the energy and mass balance. The power conversion systems is the main part where solar-only operation and the increase in operational hours. Solar-only operation include the use of steam turbines, gas turbines, organic Rankine cycles and solar dishes. The operational hours can be increased with hybridization and with storage. Another important topic is the cogeneration where solar cooling, desalination and of heat usage is described. Many examples of commercial CSP power plants as well as research facilities from the past as well as current installed and in operation are described in detail. The chapter closes with economic and environmental aspects and with the future potential of the development of CSP around the world.},
  language  = {en}
}
@inproceedings{HauggKreyerKemperetal.2020,
  author    = {Haugg, Albert Thomas and Kreyer, J{\"o}rg and Kemper, Hans and Hatesuer, Katerina and Esch, Thomas},
  title     = {Heat exchanger for ORC. adaptability and optimisation potentials},
  series = {IIR International Rankine 2020 Conference},
  booktitle = {IIR International Rankine 2020 Conference},
  doi       = {10.18462/iir.rankine.2020.1224},
  pages     = {10 Seiten},
  year      = {2020},
  abstract  = {The recovery of waste heat requires heat exchangers to extract it from a liquid or gaseous medium into another working medium, a refrigerant. In Organic Rankine Cycles (ORC) on Combustion Engines there are two major heat sources, the exhaust gas and the water/glycol fluid from the engine's cooling circuit. A heat exchanger design must be adapted to the different requirements and conditions resulting from the heat sources, fluids, system configurations, geometric restrictions, and etcetera. The Stacked Shell Cooler (SSC) is a new and very specific design of a plate heat exchanger, created by AKG, which allows with a maximum degree of freedom the optimization of heat exchange rate and the reduction of the related pressure drop. This optimization in heat exchanger design for ORC systems is even more important, because it reduces the energy consumption of the system and therefore maximizes the increase in overall efficiency of the engine.},
  language  = {en}
}
@inproceedings{SchopenShabaniEschetal.2022,
  author    = {Schopen, Oliver and Shabani, Bahman and Esch, Thomas and Kemper, Hans and Shah, Neel},
  title     = {Quantitative evaluation of health management designs for fuel cell systems in transport vehicles},
  series = {2nd UNITED-SAIG International Conference Proceedings},
  booktitle = {2nd UNITED-SAIG International Conference Proceedings},
  editor    = {Rahim, S.A. and As'arry, A. and Zuhri, M.Y.M. and Harmin, M.Y. and Rezali, K.A.M. and Hairuddin, A.A.},
  pages     = {1 -- 3},
  year      = {2022},
  abstract  = {Focusing on transport vehicles, mainly with regard to aviation applications, this paper presents compilation and subsequent quantitative evaluation of methods aimed at building an optimum integrated health management solution for fuel cell systems. The methods are divided into two different main types and compiled in a related scheme. Furthermore, different methods are analysed and evaluated based on parameters specific to the aviation context of this study. Finally, the most suitable method for use in fuel cell health management systems is identified and its performance and suitability is quantified.},
  language  = {en}
}
@inproceedings{SattlerChicoCaminosAttietal.2020,
  author    = {Sattler, Johannes Christoph and Chico Caminos, Ricardo Alexander and Atti, Vikrama Nagababu and {\"U}rlings, Nicolas and Dutta, Siddharth and Ruiz, Victor and Kalogirou, Soteris and Ktistis, Panayiotis and Agathokleous, Rafaela and Alexopoulos, Spiros and Teixeira Boura, Cristiano Jos{\´e} and Herrmann, Ulf},
  title     = {Dynamic simulation tool for a performance evaluation and sensitivity study of a parabolic trough collector system with concrete thermal energy storage},
  series = {AIP Conference Proceedings 2303},
  booktitle = {AIP Conference Proceedings 2303},
  publisher = {American Institute of Physics},
  address   = {Melville, NY},
  issn      = {0094-243X},
  doi       = {10.1063/5.0029277},
  pages     = {160004},
  year      = {2020},
  language  = {de}
}
@techreport{HebelMerkensFeyerletal.2021,
  author    = {Hebel, Christoph and Merkens, Torsten and Feyerl, G{\"u}nter and Kemper, Hans and Busse, Daniel},
  title     = {Elektromobilit{\"a}t - Verbundprojekt "COSTARTebus": Comprehensive strategy to accelerate the integration of electric-buses into existing public transport systems - Teilprojekt A : Berichtszeitraum: 01.01.2018-31.10.2020},
  publisher = {Fachhochschule Aachen},
  address   = {Aachen},
  pages     = {219 Seiten},
  year      = {2021},
  language  = {de}
}
@article{LuftBremenLuft2023,
  author    = {Luft, Angela and Bremen, Sebastian and Luft, Nils},
  title     = {A cost/benefit and flexibility evaluation framework for additive technologies in strategic factory planning},
  series = {Processes},
  volume    = {11},
  journal   = {Processes},
  number    = {7},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2227-9717},
  doi       = {10.3390/pr11071968},
  pages     = {Artikel 1968},
  year      = {2023},
  abstract  = {There is a growing demand for more flexibility in manufacturing to counter the volatility and unpredictability of the markets and provide more individualization for customers. However, the design and implementation of flexibility within manufacturing systems are costly and only economically viable if applicable to actual demand fluctuations. To this end, companies are considering additive manufacturing (AM) to make production more flexible. This paper develops a conceptual model for the impact quantification of AM on volume and mix flexibility within production systems in the early stages of the factory-planning process. Together with the model, an application guideline is presented to help planners with the flexibility quantification and the factory design process. Following the development of the model and guideline, a case study is presented to indicate the potential impact additive technologies can have on manufacturing flexibility Within the case study, various scenarios with different production system configurations and production programs are analyzed, and the impact of the additive technologies on volume and mix flexibility is calculated. This work will allow factory planners to determine the potential impacts of AM on manufacturing flexibility in an early planning stage and design their production systems accordingly.},
  language  = {en}
}
@article{AbbasHedwigBalcetal.2023,
  author    = {Abbas, Karim and Hedwig, Lukas and Balc, Nicolae and Bremen, Sebastian},
  title     = {Advanced FFF of PEEK: Infill strategies and material characteristics for rapid tooling},
  series = {Polymers},
  volume    = {2023},
  journal   = {Polymers},
  number    = {15},
  publisher = {MDPI},
  address   = {Basel},
  doi       = {10.3390/polym15214293},
  pages     = {Artikel 4293},
  year      = {2023},
  abstract  = {Traditional vulcanization mold manufacturing is complex, costly, and under pressure due to shorter product lifecycles and diverse variations. Additive manufacturing using Fused Filament Fabrication and high-performance polymers like PEEK offer a promising future in this industry. This study assesses the compressive strength of various infill structures (honeycomb, grid, triangle, cubic, and gyroid) when considering two distinct build directions (Z, XY) to enhance PEEK's economic and resource efficiency in rapid tooling. A comparison with PETG samples shows the behavior of the infill strategies. Additionally, a proof of concept illustrates the application of a PEEK mold in vulcanization. A peak compressive strength of 135.6 MPa was attained in specimens that were 100\% solid and subjected to thermal post-treatment. This corresponds to a 20\% strength improvement in the Z direction. In terms of time and mechanical properties, the anisotropic grid and isotropic cubic infill have emerged for use in rapid tooling. Furthermore, the study highlights that reducing the layer thickness from 0.15 mm to 0.1 mm can result in a 15\% strength increase. The study unveils the successful utilization of a room-temperature FFF-printed PEEK mold in vulcanization injection molding. The parameters and infill strategies identified in this research enable the resource-efficient FFF printing of PEEK without compromising its strength properties. Using PEEK in rapid tooling allows a cost reduction of up to 70\% in tool production.},
  language  = {en}
}
@incollection{AtmaneHirechKassmietal.2020,
  author    = {Atmane, Ilias and Hirech, Kamal and Kassmi, K. and Mahdi, Zahra and Alexopoulos, Spiros and Schwarzer, Klemens and Chayeb, H. and Bachiri, N.},
  title     = {Design and realization of a pilot solar desalination plant in Douar El Hamri in the province of Berkane (Morocco)},
  series = {Sustainable entrepreneurship, renewable energy-based projects, and digitalization},
  booktitle = {Sustainable entrepreneurship, renewable energy-based projects, and digitalization},
  editor    = {Omrane, Amina and Kassmi, Khalil and Akram, Muhammad Wasim and Khanna, Ashish and Mostafiz, Imtiaz},
  publisher = {CRC Press},
  address   = {Boca Raton, Fa.},
  isbn      = {9781000292541 (E-Book)},
  pages     = {18 Seiten},
  year      = {2020},
  abstract  = {Producing fresh water from saline water has become one of the most difficult challenges to overcome especially with the high demand and shortage of fresh water. In this context, as part of a collaboration with Germany, the authors propose a design and implementation of a pilot multi-stage solar desalination system (MSD), remotely controlled, at Douar Al Hamri in the rural town of Boughriba in the province of Berkane, Morocco. More specifically, they present their contribution on the remote control and supervision system, which makes the functioning of the MSD system reliable and guarantees the production of drinking water for the population of Douar. The results obtained show that the electronic cards and computer communication software implemented allow the acquisition of all electrical (currents, voltages, powers, yields), thermal (temperatures of each stage), and meteorological (irradiance and ambient temperature), remote control and maintenance (switching on, off, data transfer). By comparing with the literature carried out in the field of solar energy, the authors conclude that the MSD and electronic desalination systems realized during this work represent a contribution in terms of the reliability and durability of providing drinking water in rural and urban areas.},
  language  = {en}
}
@inproceedings{ElMoussaouiKassmiAlexopoulosetal.2021,
  author    = {El Moussaoui, Noureddine and Kassmi, Khalil and Alexopoulos, Spiros and Schwarzer, Klemens and Chayeb, Hamid and Bachiri, Najib},
  title     = {Simulation studies on a new innovative design of a hybrid solar distiller MSDH alimented with a thermal and photovoltaic energy},
  series = {Materialstoday: Proceedings},
  volume    = {45},
  booktitle = {Materialstoday: Proceedings},
  number    = {8},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2214-7853},
  doi       = {10.1016/j.matpr.2021.03.115},
  pages     = {7653 -- 7660},
  year      = {2021},
  abstract  = {In this paper, we present the structure, the simulation the operation of a multi-stage, hybrid solar desalination system (MSDH), powered by thermal and photovoltaic (PV) (MSDH) energy. The MSDH system consists of a lower basin, eight horizontal stages, a field of four flat thermal collectors with a total area of 8.4 m2, 3 Kw PV panels and solar batteries. During the day the system is heated by thermal energy, and at night by heating resistors, powered by solar batteries. These batteries are charged by the photovoltaic panels during the day. More specifically, during the day and at night, we analyse the temperature of the stages and the production of distilled water according to the solar irradiation intensity and the electric heating power, supplied by the solar batteries. The simulations were carried out in the meteorological conditions of the winter month (February 2020), presenting intensities of irradiance and ambient temperature reaching 824 W/m2 and 23 °C respectively. The results obtained show that during the day the system is heated by the thermal collectors, the temperature of the stages and the quantity of water produced reach 80 °C and 30 Kg respectively. At night, from 6p.m. the system is heated by the electric energy stored in the batteries, the temperature of the stages and the quantity of water produced reach respectively 90 °C and 104 Kg for an electric heating power of 2 Kw. Moreover, when the electric power varies from 1 Kw to 3 Kw the quantity of water produced varies from 92 Kg to 134 Kg. The analysis of these results and their comparison with conventional solar thermal desalination systems shows a clear improvement both in the heating of the stages, by 10\%, and in the quantity of water produced by a factor of 3.},
  language  = {en}
}
@article{AbbasBalcBremenetal.2022,
  author    = {Abbas, Karim and Balc, Nicolae and Bremen, Sebastian and Skupin, Marco},
  title     = {Crystallization and aging behavior of polyetheretherketone PEEK within rapid tooling and rubber molding},
  series = {Journal of Manufacturing and Materials Processing},
  volume    = {6},
  journal   = {Journal of Manufacturing and Materials Processing},
  number    = {5},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2504-4494},
  doi       = {10.3390/jmmp6050093},
  pages     = {1 -- 12},
  year      = {2022},
  abstract  = {In times of short product life cycles, additive manufacturing and rapid tooling are important methods to make tool development and manufacturing more efficient. High-performance polymers are the key to mold production for prototypes and small series. However, the high temperatures during vulcanization injection molding cause thermal aging and can impair service life. The extent to which the thermal stress over the entire process chain stresses the material and whether it leads to irreversible material aging is evaluated. To this end, a mold made of PEEK is fabricated using fused filament fabrication and examined for its potential application. The mold is heated to 200 ◦C, filled with rubber, and cured. A differential scanning calorimetry analysis of each process step illustrates the crystallization behavior and first indicates the material resistance. It shows distinct cold crystallization regions at a build chamber temperature of 90 ◦C. At an ambient temperature above Tg, crystallization of 30\% is achieved, and cold crystallization no longer occurs. Additional tensile tests show a decrease in tensile strength after ten days of thermal aging. The steady decrease in recrystallization temperature indicates degradation of the additives. However, the tensile tests reveal steady embrittlement of the material due to increasing crosslinking.},
  language  = {en}
}
@article{KurulganDemirciDemirciLinderetal.2012,
  author    = {Kurulgan Demirci, Eylem and Demirci, Taylan and Linder, Peter and Trzewik, J{\"u}rgen and Gierkowski, Jessica Ricarda and Gossmann, Matthias and Kayser, Peter and Porst, Dariusz and Digel, Ilya and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l},
  title     = {rhAPC reduces the endothelial cell permeability via a decrease of contractile tensions induced by endothelial cells},
  series = {Journal of Bioscience and Bioengineering},
  volume    = {113},
  journal   = {Journal of Bioscience and Bioengineering},
  number    = {2},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1347-4421},
  doi       = {10.1016/j.jbiosc.2012.03.019},
  pages     = {212 -- 219},
  year      = {2012},
  abstract  = {All cells generate contractile tension. This strain is crucial for mechanically controlling the cell shape, function and survival. In this study, the CellDrum technology quantifying cell's (the cellular) mechanical tension on a pico-scale was used to investigate the effect of lipopolysaccharide (LPS) on human aortic endothelial cell (HAoEC) tension. The LPS effect during gram-negative sepsis on endothelial cells is cell contraction causing endothelium permeability increase. The aim was to finding out whether recombinant activated protein C (rhAPC) would reverse the endothelial cell response in an in-vitro sepsis model. In this study, the established in-vitro sepsis model was confirmed by interleukin 6 (IL-6) levels at the proteomic and genomic levels by ELISA, real time-PCR and reactive oxygen species (ROS) activation by florescence staining. The thrombin cellular contraction effect on endothelial cells was used as a positive control when the CellDrum technology was applied. Additionally, the Ras homolog gene family, member A (RhoA) mRNA expression level was checked by real time-PCR to support contractile tension results. According to contractile tension results, the mechanical predominance of actin stress fibers was a reason of the increased endothelial contractile tension leading to enhanced endothelium contractility and thus permeability enhancement. The originality of this data supports firstly the basic measurement principles of the CellDrum technology and secondly that rhAPC has a beneficial effect on sepsis influenced cellular tension. The technology presented here is promising for future high-throughput cellular tension analysis that will help identify pathological contractile tension responses of cells and prove further cell in-vitro models.},
  language  = {en}
}
@book{ArtmannTemizArtmannZhubanovaetal.2018,
  author    = {Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Zhubanova, Azhar A. and Digel, Ilya},
  title     = {Biological, physical and technical basics of cell engineering},
  editor    = {Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Zhubanova, Azhar A. and Digel, Ilya},
  publisher = {Springer},
  address   = {Singapore},
  isbn      = {978-981-10-7903-0},
  pages     = {xxiv, 481 Seiten ; Illustrationen, Diagramme},
  year      = {2018},
  language  = {en}
}
@misc{OPUS4-7863,
  title     = {Dimensionen 2-2012 : Magazin der FH Aachen University of Applied Sciences},
  address   = {Aachen},
  organization    = {FH Aachen, University of Applied Sciences},
  pages     = {88 S.},
  year      = {2012},
  abstract  = {Thema 06 Alles ist jetzt | Zeit ist f{\"u}r uns allgegenw{\"a}rtig, sie bestimmt unser Leben. Eine kurze Reise in die Geschichte der Zeit. 10 Raumfahrt-Visionen von einst und heute | 25. Raumfahrtkolloquium des Fachbereichs Luft- und Raumfahrttechnik 12 Aufbruch in eine neue Welt | Essay von Prof. Dr. h.c. Jesco Freiherr von Puttkamer zum 100. Geburtstag von Wernher von Braun 16 Gesucht: Ein Impfstoff gegen Krebs | Prof. Dr. Peter {\"O}hlschl{\"a}ger forscht an Impfstoffen, die die Ausbreitung von Krebs bek{\"a}mpfen sollen 18 Gesichter der Zukunft | An der FH kommen menschen{\"a}hnliche Roboter zum Einsatz, die sogar Fußball spielen k{\"o}nnen 20 Sicher in der Luft | FH Aachen entwickelt mit der Sinn Spezialuhren GmbH technischen Standard f{\"u}r Fliegeruhren 24 Der „Eismaulwurf" gr{\"a}bt sich durch die Schweiz | IceMole soll bei der Untersuchung von unterirdischen Gletscherseen helfen Studium 26 Benzin im Blut | {\"U}ber die Arbeit im Aixtreme-Racing-Team hat Michael Roeske den Weg zu BMW Motorsport gefunden 28 Hervorragende Perspektiven | Duale Studieng{\"a}nge in Kooperation mit der Handwerkskammer 30 Frei wie ein Vogel | 24 Studierende lernen die Grundlagen des Segelfliegens kennen 32 Vom Autow{\"a}scher zum Ingenieur | Karriere mit f{\"u}nf Sternen 33 Miteinander arbeiten, praktisch {\"u}berzeugen | Das Projekt pro8 fordert Teamf{\"a}higkeit, Zeitmanagement, Pr{\"a}sentationstechniken und Fachwissen 34 Willkommene F{\"o}rderung | Studiengang Scientific Programming erh{\"a}lt Stiftungsprofessur 35 Von Zeltd{\"a}chern und Strohhalmen | Wettbewerb zur Erweiterung des CHIO-Gel{\"a}ndes 36 Mehr B{\"u}rgerbeteiligung in der St{\"a}dteregion | FH-Studentinnen entwickeln gemeinsam mit Prof. Dr. Claudia Mayer das Konzept 37 Ferngesteuertes Labor | Studierende k{\"o}nnen jetzt von zu Hause aus an Antriebs- und Steuerungskomponenten arbeiten 38 Der Koloss von J{\"u}lich | Teilnehmer der 27. Summer School Renewable Energy besuchen den Solarturm in J{\"u}lich 40 Meldungen/Studium International 42 Fliegende Ingenieure | Studium Luft- und Raumfahrttechnik wird mit einer Ausbildung zum Verkehrspiloten verkn{\"u}pft 44 Arbeitstagung Internationalisierung | Grenz{\"u}berschreitende Zusammenarbeit wird an der FH weiter ausgebaut 45 Meldungen/ International Benzin im Blut | Schon als Kind war Michael Roeske motorsportverr{\"u}ckt. {\"U}ber die Arbeit im Aixtreme-RacingTeam hat er den Weg zu BMW Motorsport gefunden FORSCHUNG UND TRANSFER 46 Der Hamster, der 1958 starb und Sp{\"u}rnase wurde | Der FH-Doktorand Ulrich Bohrn arbeitet mit lebenden Zellen 48 Leuchtende Weltneuheit | FH-Wissenschaftler entwickeln quecksilberfreie Energiesparlampe 50 Zellen erinnern sich | FH-Professor entdeckt neuen Effekt bei der Untersuchung roter Blutk{\"o}rperchen 52 Provokation allein reicht nicht mehr | Prof. Dr. Sabine Fabo erforscht die Arbeit moderner K{\"u}nstler 54 FH und LKA gemeinsam gegen Computerkriminalit{\"a}t | Neue Strategien zur Pr{\"a}vention und zur Strafverfolgung 55 Meldungen/Forschung und Transfer Personen 56 Der Tiger und sein Meister | Interview mit dem Aachener K{\"u}nstler Eric Peters 60 Interessen vereinigen | Honorarkonsulin Prof. Dr. Christiane Vaeßen setzt sich f{\"u}r grenz{\"u}berschreitende Kooperation ein 61 Die zwei Seelen | FH-Absolventin Monika Koch hat sich in der Region etabliert 62 Die FH Aachen trauert um Prof. Dr. Rolf-Dietmar Grap 63 Ein Mann der ersten Stunde | Die FH Aachen trauert um Kanzler a. D. Peter Michael Reusch 64 Neue Dekane treten ihr Amt an | Sechs der zehn FH-Fachbereiche stehen unter neuer Leitung 65 Mitglieder des Senats und der Fachbereichsr{\"a}te 68 Lehrpreis 2012, Lehrpr{\"a}mien 2011/12 69 Dienstjubil{\"a}en, B{\"u}cher /Neuauflagen 70 Neuberufene Professoren 71 Meldungen/Personen SERVICE 72 Platz f{\"u}r 1000 Studierende | Neues H{\"o}rsaalgeb{\"a}ude in der Eupener Straße feierlich er{\"o}ffnet 74 Der Blick geht nach vorn | FH peilt die Reauditierung als „familiengerechte Hochschule" an 75 So sch{\"o}n kann Helfen sein | „Menschen f{\"u}r Menschen"- Botschafterin Sara Nuru zu Gast an der FH 76 Wie w{\"a}rs mit MINT? | Die Wanderausstellung „Technik ist weiblich" begeistert M{\"a}dchen f{\"u}r Naturwissenschaften 77 Preis f{\"u}r Technologietransfer | TeTRRA-Projekt zeichnet FH-Absolventen aus 78 Meldungen/Service, Messen und Veranstaltungen 86 Ortswechsel /Zeitreise per Rad 87 Impressum},
  language  = {de}
}