@article{EngelmannPourshahidiShalabyetal.2022, author = {Engelmann, Ulrich M. and Pourshahidi, Mohammad Ali and Shalaby, Ahmed and Krause, Hans-Joachim}, title = {Probing particle size dependency of frequency mixing magnetic detection with dynamic relaxation simulation}, series = {Journal of Magnetism and Magnetic Materials}, volume = {563}, journal = {Journal of Magnetism and Magnetic Materials}, number = {In progress, Art. No. 169965}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0304-8853}, doi = {10.1016/j.jmmm.2022.169965}, year = {2022}, abstract = {Biomedical applications of magnetic nanoparticles (MNP) fundamentally rely on the particles' magnetic relaxation as a response to an alternating magnetic field. The magnetic relaxation complexly depends on the interplay of MNP magnetic and physical properties with the applied field parameters. It is commonly accepted that particle core size is a major contributor to signal generation in all the above applications, however, most MNP samples comprise broad distribution spanning nm and more. Therefore, precise knowledge of the exact contribution of individual core sizes to signal generation is desired for optimal MNP design generally for each application. Specifically, we present a magnetic relaxation simulation-driven analysis of experimental frequency mixing magnetic detection (FMMD) for biosensing to quantify the contributions of individual core size fractions towards signal generation. Applying our method to two different experimental MNP systems, we found the most dominant contributions from approx. 20 nm sized particles in the two independent MNP systems. Additional comparison between freely suspended and immobilized MNP also reveals insight in the MNP microstructure, allowing to use FMMD for MNP characterization, as well as to further fine-tune its applicability in biosensing.}, language = {en} } @article{EngelmannBuhlDraacketal.2018, author = {Engelmann, Ulrich M. and Buhl, Eva Miriam and Draack, Sebastian and Viereck, Thilo and Frank, and Schmitz-Rode, Thomas and Slabu, Ioana}, title = {Magnetic relaxation of agglomerated and immobilized iron oxide nanoparticles for hyperthermia and imaging applications}, series = {IEEE Magnetic Letters}, volume = {9}, journal = {IEEE Magnetic Letters}, number = {Article number 8519617}, publisher = {IEEE}, address = {New York, NY}, issn = {1949-307X}, doi = {10.1109/LMAG.2018.2879034}, year = {2018}, abstract = {Magnetic nanoparticles (MNPs) are used as therapeutic and diagnostic agents for local delivery of heat and image contrast enhancement in diseased tissue. Besides magnetization, the most important parameter that determines their performance for these applications is their magnetic relaxation, which can be affected when MNPs immobilize and agglomerate inside tissues. In this letter, we investigate different MNP agglomeration states for their magnetic relaxation properties under excitation in alternating fields and relate this to their heating efficiency and imaging properties. With focus on magnetic fluid hyperthermia, two different trends in MNP heating efficiency are measured: an increase by up to 23\% for agglomerated MNP in suspension and a decrease by up to 28\% for mixed states of agglomerated and immobilized MNP, which indicates that immobilization is the dominant effect. The same comparatively moderate effects are obtained for the signal amplitude in magnetic particle spectroscopy.}, language = {en} } @article{EngelmannBuhlBaumannetal.2017, author = {Engelmann, Ulrich M. and Buhl, Eva Miriam and Baumann, Martin and Schmitz-Rode, Thomas and Slabu, Ioana}, title = {Agglomeration of magnetic nanoparticles and its effects on magnetic hyperthermia}, series = {Current Directions in Biomedical Engineering}, volume = {3}, journal = {Current Directions in Biomedical Engineering}, number = {2}, publisher = {De Gruyter}, address = {Berlin}, issn = {2364-5504}, doi = {10.1515/cdbme-2017-0096}, pages = {457 -- 460}, year = {2017}, language = {en} } @article{EngelHoltmannUlberetal.2018, author = {Engel, Mareike and Holtmann, Dirk and Ulber, Roland and Tippk{\"o}tter, Nils}, title = {Increased Biobutanol Production by Mediator-Less Electro-Fermentation}, series = {Biotechnology Journal}, volume = {14}, journal = {Biotechnology Journal}, number = {4}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1860-7314}, doi = {10.1002/biot.201800514}, year = {2018}, abstract = {A future bio-economy should not only be based on renewable raw materials but also in the raise of carbon yields of existing production routes. Microbial electrochemical technologies are gaining increased attention for this purpose. In this study, the electro-fermentative production of biobutanol with C. acetobutylicum without the use of exogenous mediators is investigated regarding the medium composition and the reactor design. It is shown that the use of an optimized synthetic culture medium allows higher product concentrations, increased biofilm formation, and higher conductivities compared to a synthetic medium supplemented with yeast extract. Moreover, the optimization of the reactor system results in a doubling of the maximum product concentrations for fermentation products. When a working electrode is polarized at -600 mV vs. Ag/AgCl, a shift from butyrate to acetone and butanol production is induced. This leads to an increased final solvent yield of Yᴀᴃᴇ = 0.202 gg⁻¹ (control 0.103 gg⁻¹), which is also reflected in a higher carbon efficiency of 37.6\% compared to 23.3\% (control) as well as a fourfold decrease in simplified E-factor to 0.43. The results are promising for further development of biobutanol production in bioelectrochemical systems in order to fulfil the principles of Green Chemistry.}, language = {en} } @article{EngelGemuendeHoltmannetal.2019, author = {Engel, Mareike and Gem{\"u}nde, Andre and Holtmann, Dirk and M{\"u}ller-Renno, Christine and Ziegler, Christiane and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {Clostridium acetobutylicum's connecting world: cell appendage formation in bioelectrochemical systems}, series = {ChemElectroChem}, volume = {7}, journal = {ChemElectroChem}, number = {2}, publisher = {Wiley}, address = {Weinheim}, issn = {2196-0216}, doi = {10.1002/celc.201901656}, pages = {414 -- 420}, year = {2019}, abstract = {Bacterial cell appendix formation supports cell-cell interaction, cell adhesion and cell movement. Additionally, in bioelectrochemical systems (BES), cell appendages have been shown to participate in extracellular electron transfer. In this work, the cell appendix formation of Clostridium acetobutylicum in biofilms of a BES are imaged and compared with conventional biofilms. Under all observed conditions, the cells possess filamentous appendages with a higher number and density in the BES. Differences in the amount of extracellular polymeric substance in the biofilms of the electrodes lead to the conclusion that the cathode can be used as electron donor and the anode as electron acceptor by C. acetobutylicum. When using conductive atomic force microscopy, a current response of about 15 nA is found for the cell appendages from the BES. This is the first report of conductivity for clostridial cell appendices and represents the basis for further studies on their role for biofilm formation and electron transfer.}, language = {en} } @article{EngelBayerHoltmannetal.2019, author = {Engel, Mareike and Bayer, Hendrik and Holtmann, Dirk and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {Flavin secretion of Clostridium acetobutylicum in a bioelectrochemical system - Is an iron limitation involved?}, series = {Bioelectrochemistry}, journal = {Bioelectrochemistry}, number = {In Press, Accepted Manuscript}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1567-5394}, doi = {10.1016/j.bioelechem.2019.05.014}, year = {2019}, language = {en} } @article{EmontsBuyel2023, author = {Emonts, Jessica and Buyel, Johannes Felix}, title = {An overview of descriptors to capture protein properties - Tools and perspectives in the context of QSAR modeling}, series = {Computational and Structural Biotechnology Journal}, journal = {Computational and Structural Biotechnology Journal}, number = {21}, publisher = {Research Network of Computational and Structural Biotechnology}, address = {Gotenburg}, issn = {2001-0370 (online-ressource)}, doi = {10.1016/j.csbj.2023.05.022}, pages = {3234 -- 3247}, year = {2023}, abstract = {Proteins are important ingredients in food and feed, they are the active components of many pharmaceutical products, and they are necessary, in the form of enzymes, for the success of many technical processes. However, production can be challenging, especially when using heterologous host cells such as bacteria to express and assemble recombinant mammalian proteins. The manufacturability of proteins can be hindered by low solubility, a tendency to aggregate, or inefficient purification. Tools such as in silico protein engineering and models that predict separation criteria can overcome these issues but usually require the complex shape and surface properties of proteins to be represented by a small number of quantitative numeric values known as descriptors, as similarly used to capture the features of small molecules. Here, we review the current status of protein descriptors, especially for application in quantitative structure activity relationship (QSAR) models. First, we describe the complexity of proteins and the properties that descriptors must accommodate. Then we introduce descriptors of shape and surface properties that quantify the global and local features of proteins. Finally, we highlight the current limitations of protein descriptors and propose strategies for the derivation of novel protein descriptors that are more informative.}, language = {en} } @article{EmonsHuellenkremerSchoening2001, author = {Emons, H. and H{\"u}llenkremer, B. and Sch{\"o}ning, Michael Josef}, title = {Detection of metal ions in aqueous solutions by voltohmmetry}, series = {Fresenius' Journal of Analytical Chemistry. 369 (2001), H. 1}, journal = {Fresenius' Journal of Analytical Chemistry. 369 (2001), H. 1}, isbn = {0937-0633}, pages = {42 -- 46}, year = {2001}, language = {en} } @article{EmonsGlueckSchoening2001, author = {Emons, H. and Gl{\"u}ck, O. and Sch{\"o}ning, Michael Josef}, title = {Voltohmmetry - An alternative detection principle at ultrathin metal electrodes in solution}, series = {Chemical and biological sensors and analytical methods : proceedings of the international symposium / Sensor, Physical Electrochemistry, and Organic and Biological Electrochemistry Divisions. Ed.: M. Butler}, journal = {Chemical and biological sensors and analytical methods : proceedings of the international symposium / Sensor, Physical Electrochemistry, and Organic and Biological Electrochemistry Divisions. Ed.: M. Butler}, publisher = {Electrochemical Society}, address = {Pennington, NJ}, isbn = {1-56677-351-2}, pages = {1 -- 3}, year = {2001}, language = {en} } @article{EmonsGlueckHuellenkremeretal.2001, author = {Emons, H. and Gl{\"u}ck, O. and H{\"u}llenkremer, B. and Sch{\"o}ning, Michael Josef}, title = {Voltohmmetry as an alternative detection method at polycrystalline metal film electrodes}, series = {Electroanalysis. 13 (2001), H. 8-9}, journal = {Electroanalysis. 13 (2001), H. 8-9}, isbn = {1040-0397}, pages = {677 -- 680}, year = {2001}, language = {en} } @article{EmonsBaadeSchoening2000, author = {Emons, H. and Baade, A. and Sch{\"o}ning, Michael Josef}, title = {Voltammetric determination of heavy metals in microvolumes of rain water}, series = {Electroanalysis. 12 (2000), H. 15}, journal = {Electroanalysis. 12 (2000), H. 15}, isbn = {1040-0397}, pages = {1171 -- 1176}, year = {2000}, language = {en} } @article{EmigHebelSchwark2022, author = {Emig, J. and Hebel, Christoph and Schwark, A.}, title = {Einsatzbereiche f{\"u}r Verkehrsnachfragemodelle}, series = {Straßenverkehrstechnik}, volume = {66}, journal = {Straßenverkehrstechnik}, number = {10}, publisher = {Kirschbaum Verlag GmbH}, address = {Bonn}, issn = {0039-2219}, doi = {10.53184/SVT10-2022-2}, pages = {727 -- 736}, year = {2022}, abstract = {In der Praxis bestehen vielf{\"a}ltige Einsatzbereiche f{\"u}r Verkehrsnachfragemodelle. Mit ihnen k{\"o}nnen Kenngr{\"o}ßen des Verkehrsangebots und der Verkehrsnachfrage f{\"u}r den heutigen Zustand wie auch f{\"u}r zuk{\"u}nftige Zust{\"a}nde bereitgestellt werden, um so die Grundlagen f{\"u}r verkehrsplanerische Entscheidungen zu liefern. Die neuen „Empfehlungen zum Einsatz von Verkehrsnachfragemodellen f{\"u}r den Personenverkehr" (EVNM-PV) (FGSV 2022) veranschaulichen anhand von typischen Planungsaufgaben, welche differenzierten Anforderungen daraus f{\"u}r die Modellkonzeption und -erstellung resultieren. Vor dem Hintergrund der konkreten Aufgabenstellung sowie deren spezifischer planerischer Anforderungen bildet die abzuleitende Modellspezifikation die verabredete Grundlage zwischen Auftraggeber und Modellersteller f{\"u}r die konkrete inhaltliche, fachliche Ausgestaltung des Verkehrsmodells.}, language = {de} } @article{EmhardtJarodzkaBrandGruweletal.2022, author = {Emhardt, Selina N. and Jarodzka, Halszka and Brand-Gruwel, Saskia and Drumm, Christian and Niehorster, Diederick C. and van Gog, Tamara}, title = {What is my teacher talking about? Effects of displaying the teacher's gaze and mouse cursor cues in video lectures on students' learning}, series = {Journal of Cognitive Psychology}, journal = {Journal of Cognitive Psychology}, publisher = {Routledge, Taylor \& Francis Group}, address = {Abingdon}, issn = {2044-5911}, doi = {10.1080/20445911.2022.2080831}, pages = {1 -- 19}, year = {2022}, abstract = {Eye movement modelling examples (EMME) are instructional videos that display a teacher's eye movements as "gaze cursor" (e.g. a moving dot) superimposed on the learning task. This study investigated if previous findings on the beneficial effects of EMME would extend to online lecture videos and compared the effects of displaying the teacher's gaze cursor with displaying the more traditional mouse cursor as a tool to guide learners' attention. Novices (N = 124) studied a pre-recorded video lecture on how to model business processes in a 2 (mouse cursor absent/present) × 2 (gaze cursor absent/present) between-subjects design. Unexpectedly, we did not find significant effects of the presence of gaze or mouse cursors on mental effort and learning. However, participants who watched videos with the gaze cursor found it easier to follow the teacher. Overall, participants responded positively to the gaze cursor, especially when the mouse cursor was not displayed in the video.}, language = {en} } @article{EmhardtJarodzkaBrandGruweletal.2020, author = {Emhardt, Selina and Jarodzka, Halszka and Brand-Gruwel, Saskia and Drumm, Christian and Gog, Tamara van}, title = {Introducing eye movement modeling examples for programming education and the role of teacher's didactic guidance}, series = {ETRA '20 Short Papers: ACM Symposium on Eye Tracking Research and Applications}, journal = {ETRA '20 Short Papers: ACM Symposium on Eye Tracking Research and Applications}, number = {Art. 52}, publisher = {ACM}, address = {New York}, doi = {10.1145/3379156.3391978}, pages = {1 -- 4}, year = {2020}, abstract = {In this article, we introduce how eye-tracking technology might become a promising tool to teach programming skills, such as debugging with 'Eye Movement Modeling Examples' (EMME). EMME are tutorial videos that visualize an expert's (e.g., a programming teacher's) eye movements during task performance to guide students' attention, e.g., as a moving dot or circle. We first introduce the general idea behind the EMME method and present studies that showed first promising results regarding the benefits of EMME to support programming education. However, we argue that the instructional design of EMME varies notably across them, as evidence-based guidelines on how to create effective EMME are often lacking. As an example, we present our ongoing research on the effects of different ways to instruct the EMME model prior to video creation. Finally, we highlight open questions for future investigations that could help improving the design of EMME for (programming) education.}, language = {en} } @article{ElsenKraissKrumbiegeletal.1999, author = {Elsen, Ingo and Kraiss, Karl-Friedrich and Krumbiegel, Dirk and Walter, Peter and Wickel, Jochen}, title = {Visual information retrieval for 3D product identification: a midterm report}, series = {KI - K{\"u}nstliche Intelligenz}, volume = {13}, journal = {KI - K{\"u}nstliche Intelligenz}, number = {1}, publisher = {Springer}, address = {Berlin}, issn = {1610-1987}, pages = {64 -- 67}, year = {1999}, language = {en} } @article{ElsenKraiss1999, author = {Elsen, Ingo and Kraiss, Karl-Friedrich}, title = {System concept and realization of a scalable neurocomputing architecture}, series = {Systems Analysis Modelling Simulation}, volume = {35}, journal = {Systems Analysis Modelling Simulation}, number = {4}, publisher = {Gordon and Breach Science Publishers}, address = {Amsterdam}, issn = {0232-9298}, pages = {399 -- 419}, year = {1999}, abstract = {This paper describes the realization of a novel neurocomputer which is based on the concepts of a coprocessor. In contrast to existing neurocomputers the main interest was the realization of a scalable, flexible system, which is capable of computing neural networks of arbitrary topology and scale, with full independence of special hardware from the software's point of view. On the other hand, computational power should be added, whenever needed and flexibly adapted to the requirements of the application. Hardware independence is achieved by a run time system which is capable of using all available computing power, including multiple host CPUs and an arbitrary number of neural coprocessors autonomously. The realization of arbitrary neural topologies is provided through the implementation of the elementary operations which can be found in most neural topologies.}, language = {en} } @article{ElsenHartungHornetal.2001, author = {Elsen, Ingo and Hartung, Frank and Horn, Uwe and Kampmann, Markus and Peters, Liliane}, title = {Streaming technology in 3G mobile communication systems}, series = {Computer : innovative technology for computer professionals}, volume = {34}, journal = {Computer : innovative technology for computer professionals}, number = {9 Seiten}, editor = {Voas, Jeffrey}, publisher = {IEEE}, address = {New York}, issn = {0018-9162}, pages = {46 -- 52}, year = {2001}, abstract = {Third-generation mobile communication systems will combine standardized streaming with a range of unique services to provide high-quality Internet content that meets the specific needs of the rapidly growing mobile market.}, language = {en} } @article{EllrichLind2012, author = {Ellrich, Thomas and Lind, Thorsten Patric}, title = {Die 'kalte Zwangsverwaltung' durch den Insolvenzverwalter}, series = {Forderungs-Praktiker : WIKI}, journal = {Forderungs-Praktiker : WIKI}, number = {1}, publisher = {FCH}, address = {Heidelberg}, pages = {16 -- 21}, year = {2012}, language = {de} } @article{EllerwegRitzSchuhmann2009, author = {Ellerweg, Roland and Ritz, Thomas and Schuhmann, Stefan}, title = {Anwendungsentwicklung f{\"u}r iPhone und Windows Mobile : ein bisschen von allem}, series = {iX : Magazin f{\"u}r professionelle Informationstechnik}, journal = {iX : Magazin f{\"u}r professionelle Informationstechnik}, number = {3}, issn = {0935-9680 (Print)}, pages = {132 -- 135}, year = {2009}, language = {de} } @article{ElbersZangBuck1990, author = {Elbers, Gereon and Zang, Thorsten and Buck, Manfred}, title = {Ruß-Immissionsmessungen im Einflußbereich des Kraftfahrzeugverkehrs}, series = {Staub, Reinhaltung der Luft : air quality control. 50 (1990)}, journal = {Staub, Reinhaltung der Luft : air quality control. 50 (1990)}, isbn = {0039-0771}, pages = {93}, year = {1990}, language = {de} }