@article{ArreolaKeusgenWagneretal.2019, author = {Arreola, Julio and Keusgen, Michael and Wagner, Torsten and Sch{\"o}ning, Michael Josef}, title = {Combined calorimetric gas- and spore-based biosensor array for online monitoring and sterility assurance of gaseous hydrogen peroxide in aseptic filling machines}, series = {Biosensors and Bioelectronics}, volume = {143}, journal = {Biosensors and Bioelectronics}, number = {111628}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0956-5663}, doi = {10.1016/j.bios.2019.111628}, year = {2019}, language = {en} } @article{KromeHoeftSander2019, author = {Krome, Cornelia and H{\"o}ft, Jan and Sander, Volker}, title = {Clustering time series applied to energy markets}, series = {Energy Informatics}, volume = {2}, journal = {Energy Informatics}, number = {Article numer 17}, publisher = {Springer}, address = {Berlin}, issn = {2520-8942}, doi = {10.1186/s42162-019-0076-0}, pages = {1 -- 20}, year = {2019}, language = {en} } @article{QuittmannAbelAlbrachtetal.2020, author = {Quittmann, Oliver J. and Abel, Thomas and Albracht, Kirsten and Meskemper, Joshua and Foitschik, Tina and Str{\"u}der, Heiko K.}, title = {Biomechanics of handcycling propulsion in a 30-min continuous load test at lactate threshold: Kinetics, kinematics, and muscular activity in able-bodied participants}, series = {European Journal of Applied Physiology}, journal = {European Journal of Applied Physiology}, number = {120}, publisher = {Springer}, address = {Heidelberg}, issn = {1439-6327}, doi = {10.1007/s00421-020-04373-x}, pages = {1403 -- 1415}, year = {2020}, abstract = {Purpose This study aims to investigate the biomechanics of handcycling during a continuous load trial (CLT) to assess the mechanisms underlying fatigue in upper body exercise. Methods Twelve able-bodied triathletes performed a 30-min CLT at a power output corresponding to lactate threshold in a racing recumbent handcycle mounted on a stationary ergometer. During the CLT, ratings of perceived exertion (RPE), tangential crank kinetics, 3D joint kinematics, and muscular activity of ten muscles of the upper extremity and trunk were examined using motion capturing and surface electromyography. Results During the CLT, spontaneously chosen cadence and RPE increased, whereas crank torque decreased. Rotational work was higher during the pull phase. Peripheral RPE was higher compared to central RPE. Joint range of motion decreased for elbow-flexion and radial-duction. Integrated EMG (iEMG) increased in the forearm flexors, forearm extensors, and M. deltoideus (Pars spinalis). An earlier onset of activation was found for M. deltoideus (Pars clavicularis), M. pectoralis major, M. rectus abdominis, M. biceps brachii, and the forearm flexors. Conclusion Fatigue-related alterations seem to apply analogously in handcycling and cycling. The most distal muscles are responsible for force transmission on the cranks and might thus suffer most from neuromuscular fatigue. The findings indicate that peripheral fatigue (at similar lactate values) is higher in handcycling compared to leg cycling, at least for inexperienced participants. An increase in cadence might delay peripheral fatigue by a reduced vascular occlusion. We assume that the gap between peripheral and central fatigue can be reduced by sport-specific endurance training.}, language = {en} } @article{DantismRoehlenDahmenetal.2020, author = {Dantism, Shahriar and R{\"o}hlen, Desiree and Dahmen, Markus and Wagner, Torsten and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {LAPS-based monitoring of metabolic responses of bacterial cultures in a paper fermentation broth}, series = {Sensors and Actuators B: Chemical}, volume = {320}, journal = {Sensors and Actuators B: Chemical}, number = {Art. 128232}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2020.128232}, year = {2020}, abstract = {As an alternative renewable energy source, methane production in biogas plants is gaining more and more attention. Biomass in a bioreactor contains different types of microorganisms, which should be considered in terms of process-stability control. Metabolically inactive microorganisms within the fermentation process can lead to undesirable, time-consuming and cost-intensive interventions. Hence, monitoring of the cellular metabolism of bacterial populations in a fermentation broth is crucial to improve the biogas production, operation efficiency, and sustainability. In this work, the extracellular acidification of bacteria in a paper-fermentation broth is monitored after glucose uptake, utilizing a differential light-addressable potentiometric sensor (LAPS) system. The LAPS system is loaded with three different model microorganisms (Escherichia coli, Corynebacterium glutamicum, and Lactobacillus brevis) and the effect of the fermentation broth at different process stages on the metabolism of these bacteria is studied. In this way, different signal patterns related to the metabolic response of microorganisms can be identified. By means of calibration curves after glucose uptake, the overall extracellular acidification of bacterial populations within the fermentation process can be evaluated.}, language = {en} } @article{HueningDeMatteis2020, author = {H{\"u}ning, Felix and De Matteis, Stefan}, title = {Entwicklung eines taktilen HMI f{\"u}r sehbehinderte und blinde Nutzerinnen und Nutzer}, series = {Blind - sehbehindert}, volume = {140}, journal = {Blind - sehbehindert}, number = {2}, publisher = {Edition Bentheim}, address = {W{\"u}rzburg}, issn = {0176-7836}, pages = {9 -- 19}, year = {2020}, language = {de} } @article{RichterWichernGroempingetal.2020, author = {Richter, L. and Wichern, M. and Gr{\"o}mping, Markus and Robecke, U. and Haberkamp, J.}, title = {Ammonium recovery from process water of digested sludge dewatering by membrane contactors}, series = {Water Practice and Technology}, volume = {15}, journal = {Water Practice and Technology}, number = {1}, publisher = {IWA Publishing}, address = {London}, issn = {1751-231X}, doi = {10.2166/wpt.2020.002}, pages = {84 -- 91}, year = {2020}, abstract = {Membrane contactors are a promising alternative for nitrogen removal and recovery from process water compared to other physicochemical and biological sidestream treatment processes. M{\"u}nster wastewater treatment plant (WWTP) is the first municipal WWTP in Germany operating a full-scale membrane contactor system to improve the nitrogen elimination and recovery efficiency. Factors influencing the operation and membrane performance are investigated in an accompanying research project. Additional operational aspects of the applied membrane modules are investigated in detail using a bench-scale membrane contactor. First results of the full-scale application demonstrate a high nitrogen removal efficiency of >95\%.}, language = {de} } @article{MalikAbdievaUalievaetal.2019, author = {Malik, A. M. and Abdieva, G. Zh. and Ualieva, P. S. and Zhubanova, A. A. and Temiz Artmann, Ayseg{\"u}l}, title = {CКPИНИНГ МИКPOOPГAНИЗМOВ-ДECТPУКТOPOВ XЛOРOPГAНИЧECКИX ЗAГPЯЗНИТEЛEЙ}, series = {Eurasian Journal of Ecology}, volume = {61}, journal = {Eurasian Journal of Ecology}, number = {4}, issn = {2617-7358}, pages = {61 -- 71}, year = {2019}, language = {ru} } @article{SchmidtTurgutLeetal.2020, author = {Schmidt, Aaron C. and Turgut, Hatice and Le, Dao and Beloqui, Ana and Delaittre, Guillaume}, title = {Making the best of it: nitroxide-mediated polymerization of methacrylates via the copolymerization approach with functional styrenics}, series = {Polymer Chemistry}, volume = {11}, journal = {Polymer Chemistry}, number = {2}, publisher = {Royal Society of Chemistry (RSC)}, address = {Cambridge}, doi = {10.1039/C9PY01458F}, pages = {593 -- 604}, year = {2020}, abstract = {The SG1-mediated solution polymerization of methyl methacrylate (MMA) and oligo(ethylene glycol) methacrylate (OEGMA, Mₙ = 300 g mol⁻¹) in the presence of a small amount of functional/reactive styrenic comonomer is investigated. Moieties such as pentafluorophenyl ester, triphenylphosphine, azide, pentafluorophenyl, halide, and pyridine are considered. A comonomer fraction as low as 5 mol\% typically results in a controlled/living behavior, at least up to 50\% conversion. Chain extensions with styrene for both systems were successfully performed. Variation of physical properties such as refractive index (for MMA) and phase transition temperature (for OEGMA) were evaluated by comparing to 100\% pure homopolymers. The introduction of an activated ester styrene derivative in the polymerization of OEGMA allows for the synthesis of reactive and hydrophilic polymer brushes with defined thickness. Finally, using the example of pentafluorostyrene as controlling comonomer, it is demonstrated that functional PMMA-b-PS are able to maintain a phase separation ability, as evidenced by the formation of nanostructured thin films.}, language = {en} } @article{KrollLudwigs2019, author = {Kroll-Ludwigs, Kathrin}, title = {Vernachl{\"a}ssigung des unionsrechtlichen Anerkennungsprinzips durch den BGH}, series = {NJW Neue Juristische Wochenschrift}, journal = {NJW Neue Juristische Wochenschrift}, number = {32}, publisher = {Beck}, address = {M{\"u}nchen}, issn = {0341-1915}, pages = {2277 -- 2279}, year = {2019}, language = {de} } @article{RoethSlabuKessleretal.2019, author = {Roeth, A.A. and Slabu, I. and Kessler, A. and Engelmann, Ulrich M.}, title = {Local treatment of pancreatic cancer with magnetic nanoparticles}, series = {HPB}, volume = {21}, journal = {HPB}, number = {Supplement 3}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1365-182X}, doi = {10.1016/j.hpb.2019.10.959}, pages = {S868 -- S869}, year = {2019}, language = {en} } @article{WilbringEnningPfaffetal.2020, author = {Wilbring, Daniela and Enning, Manfred and Pfaff, Raphael and Schmidt, Bernd}, title = {Neue Perspektiven f{\"u}r die Bahn in der Produktions- und Distributionslogistik durch Prozessautomation}, series = {ETR - Eisenbahntechnische Rundschau}, volume = {69}, journal = {ETR - Eisenbahntechnische Rundschau}, number = {3}, issn = {0013-2845}, pages = {15 -- 19}, year = {2020}, language = {de} } @article{WeldenSchoeningWagneretal.2020, author = {Welden, Rene and Sch{\"o}ning, Michael Josef and Wagner, Patrick H. and Wagner, Torsten}, title = {Light-Addressable Electrodes for Dynamic and Flexible Addressing of Biological Systems and Electrochemical Reactions}, series = {Sensors}, volume = {20}, journal = {Sensors}, number = {6}, publisher = {MDPI}, address = {Basel}, issn = {1424-8220}, doi = {10.3390/s20061680}, pages = {Artikel 1680}, year = {2020}, abstract = {In this review article, we are going to present an overview on possible applications of light-addressable electrodes (LAE) as actuator/manipulation devices besides classical electrode structures. For LAEs, the electrode material consists of a semiconductor. Illumination with a light source with the appropiate wavelength leads to the generation of electron-hole pairs which can be utilized for further photoelectrochemical reaction. Due to recent progress in light-projection technologies, highly dynamic and flexible illumination patterns can be generated, opening new possibilities for light-addressable electrodes. A short introduction on semiconductor-electrolyte interfaces with light stimulation is given together with electrode-design approaches. Towards applications, the stimulation of cells with different electrode materials and fabrication designs is explained, followed by analyte-manipulation strategies and spatially resolved photoelectrochemical deposition of different material types.}, language = {en} } @article{KerresGredigkHoffmannJatheetal.2020, author = {Kerres, Karsten and Gredigk-Hoffmann, Sylvia and Jathe, R{\"u}diger and Orlik, Stefan and Sariyildiz, Mustafa and Schmidt, Torsten and Sympher, Klaus-Jochen and Uhlenbroch, Adrian}, title = {Future approaches for sewer system condition assessment}, series = {Water Practice \& Technology}, journal = {Water Practice \& Technology}, number = {15 (2)}, publisher = {IWA Publishing}, address = {London}, issn = {1751-231X}, doi = {10.2166/wpt.2020.027}, pages = {386 -- 393}, year = {2020}, abstract = {Different analytical approaches exist to describe the structural substance or wear reserve of sewer systems. The aim is to convert engineering assessments of often complex defect patterns into computational algorithms and determine a substance class for a sewer section or manhole. This analytically determined information is essential for strategic rehabilitation planning processes up to network level, as it corresponds to the most appropriate rehabilitation type and can thus provide decision-making support. Current calculation methods differ clearly from each other in parts, so that substance classes determined by the different approaches are only partially comparable with each other. The objective of the German R\&D cooperation project 'SubKanS' is to develop a methodology for classifying the specific defect patterns resulting from the interaction of all the individual defects, and their severities and locations. The methodology takes into account the structural substance of sewer sections and manholes, based on real data and theoretical considerations analogous to the condition classification of individual defects. The result is a catalogue of defect patterns and characteristics, as well as associated structural substance classifications of sewer systems (substance classes). The methodology for sewer system substance classification is developed so that the classification of individual defects can be transferred into a substance class of the sewer section or manhole, eventually taking into account further information (e.g. pipe material, nominal diameter, etc.). The result is a validated methodology for automated sewer system substance classification.}, language = {en} } @article{Koehler2020, author = {K{\"o}hler, Klemens}, title = {A conflict theory perspective of IT attacks - consequences for IT security education}, number = {Preprint}, year = {2020}, abstract = {Cyberspace is "the environment formed by physical and non-physical components to store, modify, and exchange data using computer networks" (NATO CCDCOE). Beyond that, it is an environment where people interact. IT attacks are hostile, non-cooperative interactions that can be described with conflict theory. Applying conflict theory to IT security leads to different objectives for end-user education, requiring different formats like agency-based competence developing games.}, language = {en} } @article{JildehKirchnerOberlaenderetal.2020, author = {Jildeh, Zaid B. and Kirchner, Patrick and Oberl{\"a}nder, Jan and Vahidpour, Farnoosh and Wagner, Patrick H. and Sch{\"o}ning, Michael Josef}, title = {Development of a package-sterilization process for aseptic filling machines: A numerical approach and validation for surface treatment with hydrogen peroxide}, series = {Sensor and Actuators A: Physical}, volume = {303}, journal = {Sensor and Actuators A: Physical}, number = {111691}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0924-4247}, doi = {10.1016/j.sna.2019.111691}, year = {2020}, abstract = {Within the present work a sterilization process by a heated gas mixture that contains hydrogen peroxide (H₂O₂) is validated by experiments and numerical modeling techniques. The operational parameters that affect the sterilization efficacy are described alongside the two modes of sterilization: gaseous and condensed H₂O₂. Measurements with a previously developed H₂O₂ gas sensor are carried out to validate the applied H₂O₂ gas concentration during sterilization. We performed microbiological tests at different H₂O₂ gas concentrations by applying an end-point method to carrier strips, which contain different inoculation loads of Geobacillus stearothermophilus spores. The analysis of the sterilization process of a pharmaceutical glass vial is performed by numerical modeling. The numerical model combines heat- and advection-diffusion mass transfer with vapor-pressure equations to predict the location of condensate formation and the concentration of H₂O₂ at the packaging surfaces by changing the gas temperature. For a sterilization process of 0.7 s, a H₂O₂ gas concentration above 4\% v/v is required to reach a log-count reduction above six. The numerical results showed the location of H₂O₂ condensate formation, which decreases with increasing sterilant-gas temperature. The model can be transferred to different gas nozzle- and packaging geometries to assure the absence of H₂O₂ residues.}, language = {en} } @article{AttarMerkKotliaretal.2019, author = {Attar, Mandana Hossein Zadeh and Merk, Hans F. and Kotliar, Konstantin and Wurpts, Gerda and R{\"o}seler, Stefani and Moll-Slodowy, Silke and Plange, Johann and Baron, Jens Malte and Balakirski, Galina}, title = {The CD63 basophil activation test as a diagnostic tool for assessing autoimmunity in patients with chronic spontaneous urticaria}, series = {European Journal of Dermatology}, volume = {29}, journal = {European Journal of Dermatology}, number = {6}, doi = {10.1684/ejd.2019.3680}, pages = {614 -- 618}, year = {2019}, language = {en} } @article{CosmaKesslerGebhardtetal.2020, author = {Cosma, Cosmin and Kessler, Julia and Gebhardt, Andreas and Campbell, Ian and Balc, Nicolae}, title = {Improving the Mechanical Strength of Dental Applications and Lattice Structures SLM Processed}, series = {Materials}, volume = {13}, journal = {Materials}, number = {4}, publisher = {MDPI}, address = {Basel}, issn = {1996-1944}, doi = {10.3390/ma13040905}, pages = {1 -- 18}, year = {2020}, abstract = {To manufacture custom medical parts or scaffolds with reduced defects and high mechanical characteristics, new research on optimizing the selective laser melting (SLM) parameters are needed. In this work, a biocompatible powder, 316L stainless steel, is characterized to understand the particle size, distribution, shape and flowability. Examination revealed that the 316L particles are smooth, nearly spherical, their mean diameter is 39.09 μm and just 10\% of them hold a diameter less than 21.18 μm. SLM parameters under consideration include laser power up to 200 W, 250-1500 mm/s scanning speed, 80 μm hatch spacing, 35 μm layer thickness and a preheated platform. The effect of these on processability is evaluated. More than 100 samples are SLM-manufactured with different process parameters. The tensile results show that is possible to raise the ultimate tensile strength up to 840 MPa, adapting the SLM parameters for a stable processability, avoiding the technological defects caused by residual stress. Correlating with other recent studies on SLM technology, the tensile strength is 20\% improved. To validate the SLM parameters and conditions established, complex bioengineering applications such as dental bridges and macro-porous grafts are SLM-processed, demonstrating the potential to manufacture medical products with increased mechanical resistance made of 316L.}, language = {en} } @article{Pietsch2015, author = {Pietsch, Wolfram}, title = {Augmenting voice of the customer analysis by analysis of belief}, series = {QFD-Forum}, journal = {QFD-Forum}, number = {30}, issn = {1431-6951}, pages = {1 -- 5}, year = {2015}, language = {en} } @article{MennickenPeterKaulenetal.2020, author = {Mennicken, Max and Peter, Sophia K. and Kaulen, Corinna and Simon, Ulrich and Karth{\"a}user, Silvia}, title = {Transport through Redox-Active Ru-Terpyridine Complexes Integrated in Single Nanoparticle Devices}, series = {The Journal of Physical Chemistry C}, volume = {124}, journal = {The Journal of Physical Chemistry C}, number = {8}, publisher = {ACS Publications}, address = {Washington, DC}, issn = {1932-7455}, doi = {10.1021/acs.jpcc.9b11716}, pages = {4881 -- 4889}, year = {2020}, abstract = {Transition metal complexes are electrofunctional molecules due to their high conductivity and their intrinsic switching ability involving a metal-to-ligand charge transfer. Here, a method is presented to contact reliably a few to single redox-active Ru-terpyridine complexes in a CMOS compatible nanodevice and preserve their electrical functionality. Using hybrid materials from 14 nm gold nanoparticles (AuNP) and bis-{4′-[4-(mercaptophenyl)-2,2′:6′,2″-terpyridine]}-ruthenium(II) complexes a device size of 30² nm² inclusive nanoelectrodes is achieved. Moreover, this method bears the opportunity for further downscaling. The Ru-complex AuNP devices show symmetric and asymmetric current versus voltage curves with a hysteretic characteristic in two well separated conductance ranges. By theoretical approximations based on the single-channel Landauer model, the charge transport through the formed double-barrier tunnel junction is thoroughly analyzed and its sensibility to the molecule/metal contact is revealed. It can be verified that tunneling transport through the HOMO is the main transport mechanism while decoherent hopping transport is present to a minor extent.}, language = {en} } @article{PilasSelmerKeusgenetal.2019, author = {Pilas, Johanna and Selmer, Thorsten and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Screen-printed carbon electrodes modified with graphene oxide for the design of a reagent-free NAD+-dependent biosensor array}, series = {Analytical Chemistry}, volume = {91}, journal = {Analytical Chemistry}, number = {23}, publisher = {ACS Publications}, address = {Washington}, doi = {10.1021/acs.analchem.9b04481}, pages = {15293 -- 15299}, year = {2019}, language = {en} }