@incollection{HoffschmidtAlexopoulosRauetal.2012, author = {Hoffschmidt, Bernhard and Alexopoulos, Spiros and Rau, Christoph and Sattler, Johannes Christoph and Anthrakidis, Anette and Teixeira Boura, Cristiano Jos{\´e} and O'Connor, P. and Hilger, Patrick}, title = {Concentrating solar power}, series = {Comprehensive renewable energy / ed. Ali Sayigh. Vol. 3: Solar thermal systems: components and applications}, volume = {3}, booktitle = {Comprehensive renewable energy / ed. Ali Sayigh. Vol. 3: Solar thermal systems: components and applications}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {978-0-08-087872-0}, doi = {10.1016/B978-0-08-087872-0.00319-X}, pages = {595 -- 636}, year = {2012}, language = {en} } @article{BeckerDelfmannEggertetal.2012, author = {Becker, J{\"o}rg and Delfmann, Patrick and Eggert, Mathias and Schwittay, Sebastian}, title = {Generalizability and Applicability of Model-Based Business Process Compliance-Checking Approaches — A State-of-the-Art Analysis and Research Roadmap}, series = {Business Research : BuR}, volume = {5}, journal = {Business Research : BuR}, number = {2}, publisher = {Springer}, address = {Heidelberg}, issn = {1866-8658}, doi = {10.1007/BF03342739}, pages = {221 -- 247}, year = {2012}, abstract = {With a steady increase of regulatory requirements for business processes, automation support of compliance management is a field garnering increasing attention in Information Systems research. Several approaches have been developed to support compliance checking of process models. One major challenge for such approaches is their ability to handle different modeling techniques and compliance rules in order to enable widespread adoption and application. Applying a structured literature search strategy, we reflect and discuss compliance-checking approaches in order to provide an insight into their generalizability and evaluation. The results imply that current approaches mainly focus on special modeling techniques and/or a restricted set of types of compliance rules. Most approaches abstain from real-world evaluation which raises the question of their practical applicability. Referring to the search results, we propose a roadmap for further research in model-based business process compliance checking.}, language = {en} } @incollection{LohseStroetmann2012, author = {Lohse, Wolfram and Stroetmann, Richard}, title = {Stahlbau}, series = {Wendehorst Bautechnische Zahlentafeln}, booktitle = {Wendehorst Bautechnische Zahlentafeln}, editor = {Vismann, Ulrich}, edition = {34}, publisher = {Vieweg + Teubner}, address = {Wiesbaden}, isbn = {978-3-8348-0960-5}, doi = {10.1007/978-3-8348-8613-2_13}, pages = {777 -- 1019}, year = {2012}, language = {de} } @inproceedings{OertelBungSchlenkhoff2012, author = {Oertel, Mario and Bung, Daniel Bernhard and Schlenkhoff, Andreas}, title = {Blocksteinrampen in Riegelbauweise : Neue Bemessungsans{\"a}tze}, series = {Staubauwerke : planen, bauen, betreiben; 35. Dresdner Wasserbaukolloquium 2012, 08. - 09. M{\"a}rz 2012}, booktitle = {Staubauwerke : planen, bauen, betreiben; 35. Dresdner Wasserbaukolloquium 2012, 08. - 09. M{\"a}rz 2012}, editor = {Carstensen, Dirk}, publisher = {Selbstverl. der Techn. Univ.}, address = {Dresden}, organization = {Technische Universit{\"a}t Dresden, Fakult{\"a}t Bauingenieurwesen}, isbn = {978-3-86780-261-1}, pages = {317 -- 326}, year = {2012}, language = {de} } @inproceedings{RitzTerhaarWallenborn2012, author = {Ritz, Thomas and Terhaar, Kristin and Wallenborn, Ramona}, title = {HMI f{\"u}r eCarSharing : ein Baustein f{\"u}r nachhaltige Mobilit{\"a}t}, series = {Mensch \& Computer 2012 - Workshopband : 12. Fach{\"u}bergreifende Konferenz f{\"u}r interaktive und kooperative Medien ; interaktiv informiert - allgegenw{\"a}rtig und allumfassend!?}, booktitle = {Mensch \& Computer 2012 - Workshopband : 12. Fach{\"u}bergreifende Konferenz f{\"u}r interaktive und kooperative Medien ; interaktiv informiert - allgegenw{\"a}rtig und allumfassend!?}, editor = {Reiterer, Harald}, publisher = {Oldenbourg}, address = {M{\"u}nchen}, isbn = {978-3-486-71990-1 (Print)}, doi = {10.1524/9783486719918.341}, pages = {381 -- 388}, year = {2012}, language = {de} } @article{Baehr2012, author = {B{\"a}hr, Brigitte}, title = {[Gert Hoepner] im Interview zum Thema ; Verpackungspolitik - mehr als H{\"u}lle}, series = {Packaging journal : Technologie, Logistik, Marketing, Produkte}, journal = {Packaging journal : Technologie, Logistik, Marketing, Produkte}, number = {5}, publisher = {Ella Verlag}, address = {H{\"u}rth}, issn = {1610-0336}, pages = {78 -- 80}, year = {2012}, language = {de} } @article{LempiaeinenCouttetBolognanietal.2012, author = {Lempi{\"a}inen, Harri and Couttet, Philippe and Bolognani, Federico and M{\"u}ller, Arne and Dubost, Val{\´e}rie and Luisier, Rapha{\"e}lle and Rio-Espinola, Alberto del and Vitry, Veronique and Unterberger, Elif B. and Thomson, John P. and Treindl, Fridolin and Metzger, Ute and Wrzodek, Clemens and Hahne, Florian and Zollinger, Tulipan and Brasa, Sarah and Kalteis, Magdalena and Marcellin, Magali and Giudicelli, Fanny and Braeuning, Albert and Morawiec, Laurent and Zamurovic, Natasa and L{\"a}ngle, Ulrich and Scheer, Nico and Sch{\"u}beler, Dirk and Goodman, Jay and Chibout, Salah-Dine and Marlowe, Jennifer and Theil, Dietlinde and Heard, David J. and Grenet, Olivier and Zell, Andreas and Templin, Markus F. and Meehan, Richard R. and Wolf, Roland C. and Elcombe, Clifford R. and Schwarz, Michael and Moulin, Pierre and Terranova, R{\´e}mi and Moggs, Jonathan G.}, title = {Identification of Dlk1-Dio3 imprinted gene cluster non-coding RNAs as novel candidate biomarkers for liver tumor promotion}, series = {Toxicological Sciences}, volume = {131}, journal = {Toxicological Sciences}, number = {2}, publisher = {Oxford University Press}, address = {Oxford}, issn = {1094-2025}, doi = {10.1093/toxsci/kfs303}, pages = {375 -- 386}, year = {2012}, abstract = {The molecular events during nongenotoxic carcinogenesis and their temporal order are poorly understood but thought to include long-lasting perturbations of gene expression. Here, we have investigated the temporal sequence of molecular and pathological perturbations at early stages of phenobarbital (PB) mediated liver tumor promotion in vivo. Molecular profiling (mRNA, microRNA [miRNA], DNA methylation, and proteins) of mouse liver during 13 weeks of PB treatment revealed progressive increases in hepatic expression of long noncoding RNAs and miRNAs originating from the Dlk1-Dio3 imprinted gene cluster, a locus that has recently been associated with stem cell pluripotency in mice and various neoplasms in humans. PB induction of the Dlk1-Dio3 cluster noncoding RNA (ncRNA) Meg3 was localized to glutamine synthetase-positive hypertrophic perivenous hepatocytes, sug- gesting a role for β-catenin signaling in the dysregulation of Dlk1-Dio3 ncRNAs. The carcinogenic relevance of Dlk1-Dio3 locus ncRNA induction was further supported by in vivo genetic dependence on constitutive androstane receptor and β-catenin pathways. Our data identify Dlk1-Dio3 ncRNAs as novel candidate early biomarkers for mouse liver tumor promotion and provide new opportunities for assessing the carcinogenic potential of novel compounds.}, language = {en} } @phdthesis{Bragard2012, author = {Bragard, Michael}, title = {The integrated emitter turn-off thyristor : an innovative MOS-gated high-power device. - (Aachener Beitr{\"a}ge des ISEA ; 62)}, publisher = {Shaker}, address = {Aachen}, isbn = {978-3-8440-1152-4}, pages = {III, 164 S. : Ill., graph. Darst.}, year = {2012}, abstract = {This thesis introduces the Integrated Emitter Turn-Off (IETO) Thyristor as a new high-power device. Known state-of-the-art research activities like the Dual GCT, the ETO thyristor and the ICT were presented and critically reviewed. A comparison with commercialized solutions identifies the pros and cons of each type of device family. Based on this analysis, the IETO structure is proposed, covering most benefits of each device class. In particular the combination of a MOS-assisted turn-off with a thyristor-based device allows a voltage-controlled MOS switching and the low on-state voltage of the thyristors. The following synthesis of an IETO device stands on a three-dimensional field of optimization spanned by electric, mechanical and thermal aspects. From an electric point of view, the lowest possible parasitic inductance and resistance within the commutation path are optimization criteria. The mechanical construction has to withstand the required contact pressure of multiple kilo Newtons. Finally, thermal borders limit the maximum average current of the device. FEM simulations covering these three aspects are performed for several design proposals. An IETO prototype is constructed and measurements on various test benches attest thermal, mechanical and electric performance. A local decoupling of the external driver stage and the presspack housing is presented by a cable connection. This separation enables a thermal and mechanical independence, which is advantageous in terms of vibrations and thermal cycles including increased reliability. The electric pulse performance of the prototype device is a factor of 3.1 above today''s solutions. In single-pulse measurements, a current up to 1600 A was successfully turned off at 115°C with an active silicon area of 823 mm². One reason for this increased turn-off capability is the extremely low-inductive construction. Additional functionality of the IETO thyristor like over-current self-protection and defined short-circuit failure state are successfully verified.}, language = {en} } @incollection{Fabo2012, author = {Fabo, Sabine}, title = {Die Kunst der Irritation und ihr Mehrwert}, series = {Vielen Dank f{\"u}r Ihren Einkauf : Konsumkultur aus Sicht von Design, Kunst und Medien}, booktitle = {Vielen Dank f{\"u}r Ihren Einkauf : Konsumkultur aus Sicht von Design, Kunst und Medien}, publisher = {Transcript Verlag}, address = {Bielefeld}, isbn = {978-3-8376-2170-9}, pages = {112 -- 145}, year = {2012}, language = {de} } @article{Wolf2012, author = {Wolf, Martin R.}, title = {Von Security Awareness zum Secure Behaviour}, series = {Hakin9 Extra - IT-Forensik}, volume = {2012}, journal = {Hakin9 Extra - IT-Forensik}, number = {5}, publisher = {Software Wydawnictwo}, address = {Warszawa}, issn = {1733-7186}, pages = {18 -- 19}, year = {2012}, abstract = {Security Awareness ist derzeit ein viel diskutiertes Thema. Es reicht nicht, einfach nur ein paar technische Systeme (z.B. Firewalls) zu installieren, um ein angemessenes Schutzniveau zu erzielen. Neben einer guten Organisation von IT Security ist es auch notwendig, den Mitarbeiter einzubinden. Der vielzitierte "Faktor Mensch" ist derjenige, der die Technik korrekt anwenden muss und der durch falsches Verhalten technische und organisatorische Schutzmaßnahmen aushebeln kann. Deshalb reicht es nicht aus, wenn sich der Mitarbeiter der Gefahren bewusst ("aware") ist, er muss auch dementsprechend "sicher" handeln.}, language = {de} } @article{RiglingElkinDobbertinetal.2012, author = {Rigling, Andreas and Elkin, Ch{\´e} and Dobbertin, Matthias and Eilmann, Britta and Giuggiola, Arnaud and Wohlgemuth, Thomas and Bugmann, Harald}, title = {Wald und Klimawandel in der inneralpinen Trockenregion Visp}, series = {Schweizerische Zeitschrift f{\"u}r Forstwesen}, volume = {163}, journal = {Schweizerische Zeitschrift f{\"u}r Forstwesen}, number = {12}, publisher = {Schweizerischer Forstverein}, address = {Z{\"u}rich}, issn = {2235-1469 (Online)}, doi = {10.3188/szf.2012.0481}, pages = {481 -- 492}, year = {2012}, abstract = {Der Temperaturanstieg der vergangenen Jahrzehnte war in Gebirgsregionen besonders ausgepr{\"a}gt. Sollte sich dieser Temperaturtrend im 21. Jahrhundert fortsetzen, dann d{\"u}rf-ten sich auch die H{\"a}ufigkeit und Intensit{\"a}t von Niederschl{\"a}-gen und Trockenperioden ver{\"a}ndern, was die Waldwirtschaft vor grosse Herausforderungen stellen wird. Trockenheit ist ein entscheidender Faktor f{\"u}r die Wald{\"o}kosysteme der inner-alpinen T{\"a}ler, wo seit Jahren trockenheitsbedingtes Baum-sterben festgestellt wird. Der vorliegende Beitrag hat zum Ziel, die Sensitivit{\"a}t der verschiedenen Wald{\"o}kosysteme ge-gen{\"u}ber Klimawandel und alternative, teilweise extreme Bewirtschaftungsvarianten in der Region Visp zu testen. Me-thodische Ans{\"a}tze wie Monitoring, Feldexperimente und dy-namische Modellierung wurden kombiniert, und es wurden verschiedene {\"O}kosystemleistungen ber{\"u}cksichtigt, so Holz-produktion, Schutz vor Naturgefahren, Kohlenstoffspeiche-rung und Aspekte der Biodiversit{\"a}t. Die Resultate deuten da-rauf hin, dass auf den Trockenstandorten der Tieflagen die einheimischen Baumarten an ihre physiologischen Grenzen stossen und l{\"a}ngerfristig {\"u}ber alternative Baumarten nach-gedacht werden sollte. In den mittleren Lagen d{\"u}rften Tro-ckenheit und Schadinsekten wie die Borkenk{\"a}fer die zuk{\"u}nf-tige Waldentwicklung steuern. In den Hochlagen hingegen werden sich die W{\"a}lder ausdehnen und besser wachsen als heute. Alle untersuchten {\"O}kosystemleistungen werden ge-bietsweise starken Ver{\"a}nderungen unterworfen sein. Die dis-kutierten Bewirtschaftungsvarianten scheinen dazu geeignet, die Wasserverf{\"u}gbarkeit der Best{\"a}nde, haupts{\"a}chlich in tief-eren Lagen, zu erh{\"o}hen und dadurch die Widerstandskraft der B{\"a}ume gegen{\"u}ber Trockenperioden vor{\"u}bergehend zu st{\"a}rken. Es ist aber davon ausgehen, dass nur verh{\"a}ltnism{\"a}s-sig starke Eingriffe wesentliche Effekte erzielen k{\"o}nnen. Die Verkn{\"u}pfung von Umweltmonitoring, Feldexperimenten und Modellierung unter Miteinbezug von {\"O}kosystemleistungen ist vielversprechend, da sie eine differenzierte Absch{\"a}tzung des zuk{\"u}nftigen Landschaftswandels und seiner Effekte auf die Waldleistungen erm{\"o}glicht.}, language = {de} } @misc{SchumannRoginSchneideretal.2012, author = {Schumann, C. and Rogin, S. and Schneider, H. and Oster, J. and Tippk{\"o}tter, Nils and Kampeis, P.}, title = {Steuerung von HGMS-Prozessen mittels Durchflusszytometrie}, series = {Chemie Ingenieur Technik}, volume = {84}, journal = {Chemie Ingenieur Technik}, number = {8}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201250125}, pages = {1370}, year = {2012}, abstract = {Die Hochgradientenmagnetseparation (HGMS) ist eine Methode zur Aufreinigung von biopharmazeutischen Produkten. Mit dieser Methode l{\"a}sst sich in nur einem Schritt eine Fest/Fest/Fl{\"u}ssig-Trennung erzielen, was zu einer erheblichen Zeit- und Kostenersparnis im Downstreaming f{\"u}hrt. Dennoch steht ihr industrieller Einsatz noch aus, was u. a. am Mangel an Analysenmethoden liegt, um die HGMS quantifizierbar zu machen. Gerade in der Pharmaproduktion werden Prozesse gebraucht, die gem{\"a}ß den einschl{\"a}gigen Vorschriften (cGMP) validiert und deren verfahrenstechnische Anlagenteile qualifiziert werden k{\"o}nnen. Die Schwierigkeit ist die Messung der magnetischen Mikrosorbentien in der Suspension, in der auch Zellen oder Zelltr{\"u}mmer vorliegen. Im Rahmen eines Forschungsprojektes im „Zentralen Innovationsprogramm Mittelstand" des BMWi wurden verschiedene Analysenmethoden untersucht. Die Durchflusszytometrie erm{\"o}glicht eine Charakterisierung von Partikeln und eine simultane quantitative Messung. Durch die multiparametrige Messung kann zwischen Zellen, Zelltr{\"u}mmern und Magnetpartikeln unterschieden werden. Die At-line-Einbindung des Durchflusszytometers ist durch den Einsatz einer externen Pumpe m{\"o}glich. {\"U}ber eine automatisierte Messwertanalyse kann der HGMS-Prozess mittels der Durchflusszytometrie gesteuert werden.}, language = {de} } @misc{LindelGreiserWaxmanetal.2012, author = {Lindel, Tomasz Dawid and Greiser, Andreas and Waxman, Patrick and Dietterle, Martin and Seifert, Frank and Fontius, Ulrich and Renz, Wolfgang and Dieringer, Matthias A. and Frauenrath, Tobias and Schulz-Menger, Jeanette and Niendorf, Thoralf and Ittermann, Bernd}, title = {Cardiac CINE MRI at 7 T using a transmit array}, series = {2012 ISMRM Annual Meeting Proceedings}, journal = {2012 ISMRM Annual Meeting Proceedings}, issn = {1545-4428}, year = {2012}, abstract = {With its need for high SNR and short acquisition times, Cardiac MRI (CMR) is an intriguing target application for ultrahigh field MRI. Due to the sheer size of the upper torso, however, the known RF issues of 7T MRI are also most prominent in CMR. Recent years brought substantial progress but the full potential of the ultrahigh field for CMR is yet to be exploited. Parallel transmission (pTx) is a promising approach in this context and several groups have already reported B1 shimming for 7T CMR. In such a static pTx application amplitudes and phases of all Tx channels are adjusted individually but otherwise imaging techniques established in current clinical practice 1.5 T and 3 T are applied. More advanced forms of pTx as spatially selective excitation (SSE) using Transmit SENSE promise additional benefits like faster imaging with reduced fields of view or improved SAR control. SSE requires the full dynamic capabilities of pTx, however, and for the majority of today's implemented pTx hardware the internal synchronization of the Tx array does not easily permit external triggering as needed for CMR. Here we report a software solution to this problem and demonstrate the feasibility of CINE CMR at 7 T using a Tx array.}, language = {en} } @incollection{Fabo2012, author = {Fabo, Sabine}, title = {Einf{\"u}hrung}, series = {Vielen Dank f{\"u}r Ihren Einkauf : Konsumkultur aus Sicht von Design, Kunst und Medien}, booktitle = {Vielen Dank f{\"u}r Ihren Einkauf : Konsumkultur aus Sicht von Design, Kunst und Medien}, publisher = {Transcript Verlag}, address = {Bielefeld}, isbn = {978-3-8376-2170-9}, pages = {9 -- 13}, year = {2012}, language = {de} } @article{FerreinMeyer2012, author = {Ferrein, Alexander and Meyer, Thomas}, title = {A Brief Overview of Artificial Intelligence in South Africa}, series = {AI Magazine}, volume = {33}, journal = {AI Magazine}, number = {1}, publisher = {AAAI}, address = {Menlo Park}, issn = {0738-4602}, doi = {10.1609/aimag.v33i1.2357}, pages = {99 -- 101}, year = {2012}, abstract = {South Africa in recent years is the establishment of a number of research hubs involved in AI activities ranging from mobile robotics and computational intelligence, to knowledge representation and reasoning, and human language technologies. In this survey we take the reader through a quick tour of the research being conducted at these hubs, and touch on an initiative to maintain and extend the current level of interest in AI research in the country.}, language = {en} } @article{BragardvanHoekDeDoncker2012, author = {Bragard, Michael and van Hoek, H. and De Doncker, R. W.}, title = {A major design step in IETO concept realization that allows overcurrent protection and pushes limits of switching performance}, series = {IEEE transactions on power electronics}, volume = {27}, journal = {IEEE transactions on power electronics}, number = {9}, publisher = {IEEE}, address = {New York}, issn = {0885-8993}, doi = {10.1109/TPEL.2012.2189136}, pages = {4163 -- 4171}, year = {2012}, abstract = {This paper presents the latest prototype of the integrated emitter turn-off thyristor concept, which potentially ranks among thyristor high-power devices like the gate turn-off thyristor and the integrated gate-commutated thyristor (IGCT). Due to modifications of the external driver stage and mechanical press-pack design optimization, this prototype allows for full device characterization. The turn-off capability was increased to 1600 A with an active silicon area of 823mm2 . This leads to a transient peak power of 672.1kW/cm² . Within this paper, measurements and concept assessment are presented and a comparison to state-of-the-art IGCT devices is provided.}, language = {en} } @misc{TippkoetterUlber2012, author = {Tippk{\"o}tter, Nils and Ulber, Roland}, title = {Rezension zu: Encyclopedia of Industrial Biotechnology, Vol. 1-7. By MC Flickinger.}, series = {Chemie Ingenieur Technik}, volume = {6}, journal = {Chemie Ingenieur Technik}, number = {84}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201290052}, pages = {936}, year = {2012}, language = {en} } @misc{TippkoetterStaubSohlingetal.2012, author = {Tippk{\"o}tter, Nils and Staub, C. and Sohling, U. and Ruf, N. and Ulber, Roland}, title = {Adsorptive Aufreinigung von Molkeproteinen}, series = {Chemie Ingenieur Technik}, volume = {84}, journal = {Chemie Ingenieur Technik}, number = {8}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201250395}, pages = {1285}, year = {2012}, abstract = {In der Molkeverarbeitung dominieren Membranfiltrationsverfahren die Prozessf{\"u}hrung. Hierbei werden {\"u}blicherweise Aufkonzentrierungen der Proteine und deren Trennung von dem Milchzucker Lactose durchgef{\"u}hrt. Der Prozess der adsorptiven Aufreinigung soll als kosteng{\"u}nstige Alternative zu den bisher gebr{\"a}uchlichen Verfahren dienen. Weiterhin er{\"o}ffnet sich durch das Verfahren die M{\"o}glichkeit, einzelne Proteinfraktionen w{\"a}hrend der Verarbeitung anzureichern. Als Proteinquellen wurden f{\"u}r die Untersuchungen Modellproteine, L{\"o}sungen aus Molkenproteinisolat, D{\"u}nnmolke und Molkekonzentrat verwendet. Die Eignung zur Proteinbindung wurden an Tonmaterialien, Silicaten und y-Aluminiumoxiden in Pulverform, in Form von Granulaten sowie Extrudaten als auch sph{\"a}rischen Partikeln {\"u}berpr{\"u}ft. Adsorbentien aus Bentonit/Silica und c-Aluminiumoxid k{\"o}nnen sowohl a-Lactalbumin (aLA) als auch b-Lactoglobulin (bLG) binden, wohingegen Materialien aus Siliciumoxid lediglich ein starkes Adsorptionsverhalten gegen{\"u}ber bLG zeigen. Mischmaterialien aus Siliciumoxid und a-Aluminiumoxid zeigen dasselbe Verhalten wie Materialien aus Siliciumoxid, weisen jedoch eine geringere Kapazit{\"a}t auf. Die Materialen wurden hinsichtlich ihres Einsatzes in chromatographischen Verfahren und Batch-Prozessen untersucht und ein Prozessentwurf f{\"u}r einen zweistufigen Batch-Prozess im R{\"u}hrkessel erarbeitet.}, language = {de} } @incollection{Fabo2012, author = {Fabo, Sabine}, title = {Gef{\"a}hrliche Liebschaften : Kunst zwischen Wderstand und Umarmung}, series = {Interventionen : Grenz{\"u}berschreitungen in {\"A}sthetik, Politik und {\"O}konomie}, booktitle = {Interventionen : Grenz{\"u}berschreitungen in {\"A}sthetik, Politik und {\"O}konomie}, editor = {Hartmann, Doreen and [u.a.],}, publisher = {Fink}, address = {M{\"u}nchen [u.a.]}, isbn = {978-3-7705-5283-2}, pages = {173 -- 189}, year = {2012}, language = {de} } @misc{TkachenkovonKnobelsdorffBrenkenhoffKleindienstetal.2012, author = {Tkachenko, Valeriy and von Knobelsdorff-Brenkenhoff, Florian and Kleindienst, Denise and Winter, Lukas and Rieger, Jan and Frauenrath, Tobias and Dieringer, Matthias A. and Santoro, Davide and Niendorf, Thoralf and Schulz-Menger, Jeanette}, title = {Cardiovasular MR at 7Tesla: assessment of the right ventricle}, series = {2012 ISMRM Annual Meeting Proceedings}, journal = {2012 ISMRM Annual Meeting Proceedings}, issn = {1545-4428}, year = {2012}, abstract = {The assessment of the right ventricle (RV) is a challenge in today's cardiology, but of growing clinical impact regarding patient prognosis in different cardiac diseases. The detection and differentiation of small wall motion abnormalities may help to enhance the differentiation of cardiomyopathies including Arrhythmogenic Rightventricular Cardiomyopathy. Cardiovascular magnetic resonance (CMR) at 1.5T is the accepted gold standard for RV quantification. The higher spatial resolution achievable at ultrahigh field strength (UHF) offers the potential to gain new insights into the structure and function of the RV. To approach this goal accurate RV chamber quantification at 7T has to be proven. Consequently this study examines the feasibility of assessment of RV dimensions and function at 7T using improved spatial resolution enabled by the intrinsic sensitivity gain of UHF CMR. For this purpose, a dedicated 16 channel TX/RX RF coil array is used together with 2D CINE fast gradient echo (FGRE) imaging. For comparison RV chamber quantification is conducted at 1.5T using a SSFP based state of the art clinical protocol.}, language = {en} }