@article{AltherrBroetzDietrichetal.2018,
  author    = {Altherr, Lena and Br{\"o}tz, Nicolas and Dietrich, Ingo and Gally, Tristan and Geßner, Felix and Kloberdanz, Hermann and Leise, Philipp and Pelz, Peter Franz and Schlemmer, Pia and Schmitt, Andreas},
  title     = {Resilience in mechanical engineering - a concept for controlling uncertainty during design, production and usage phase of load-carrying structures},
  series = {Applied Mechanics and Materials},
  volume    = {885},
  journal   = {Applied Mechanics and Materials},
  publisher = {Trans Tech Publications},
  address   = {B{\"a}ch},
  isbn      = {1662-7482},
  doi       = {10.4028/www.scientific.net/AMM.885.187},
  pages     = {187 -- 198},
  year      = {2018},
  abstract  = {Resilience as a concept has found its way into different disciplines to describe the ability of an individual or system to withstand and adapt to changes in its environment. In this paper, we provide an overview of the concept in different communities and extend it to the area of mechanical engineering. Furthermore, we present metrics to measure resilience in technical systems and illustrate them by applying them to load-carrying structures. By giving application examples from the Collaborative Research Centre (CRC) 805, we show how the concept of resilience can be used to control uncertainty during different stages of product life.},
  language  = {en}
}
@inproceedings{AlhwarinSchifferFerreinetal.2018,
  author    = {Alhwarin, Faraj and Schiffer, Stefan and Ferrein, Alexander and Scholl, Ingrid},
  title     = {Optimized KinectFusion Algorithm for 3D Scanning Applications},
  series = {Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 2: BIOIMAGING},
  booktitle = {Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 2: BIOIMAGING},
  isbn      = {978-989-758-278-3},
  doi       = {10.5220/0006594700500057},
  pages     = {50 -- 57},
  year      = {2018},
  language  = {en}
}
@inproceedings{AlhwarinFerreinScholl2018,
  author    = {Alhwarin, Faraj and Ferrein, Alexander and Scholl, Ingrid},
  title     = {CRVM: Circular Random Variable-based Matcher - A Novel Hashing Method for Fast NN Search in High-dimensional Spaces},
  series = {Proceedings of the 7th International Conference on Pattern Recognition Applications and Methods, ICPRAM 2018},
  booktitle = {Proceedings of the 7th International Conference on Pattern Recognition Applications and Methods, ICPRAM 2018},
  isbn      = {978-989-758-276-9},
  doi       = {10.5220/0006692802140221},
  pages     = {214 -- 221},
  year      = {2018},
  language  = {en}
}
@article{AlbannaKotliarLuekeetal.2018,
  author    = {Albanna, Walid and Kotliar, Konstantin and L{\"u}ke, Jan Niklas and Alpdogan, Serdar and Conzen, Catharina and Lindauer, Ute and Clusmann, Hans and Hescheler, J{\"u}rgen and Vilser, Walthard and Schneider, Toni and Schubert, Gerrit Alexander},
  title     = {Non-invasive evaluation of neurovascular coupling in the murine retina by dynamic retinal vessel analysis},
  series = {Plos one},
  volume    = {13},
  journal   = {Plos one},
  number    = {10},
  publisher = {PLOS},
  address   = {San Francisco},
  doi       = {10.1371/journal.pone.0204689},
  pages     = {e0204689},
  year      = {2018},
  abstract  = {Background Impairment of neurovascular coupling (NVC) was recently reported in the context of subarachnoid hemorrhage and may correlate with disease severity and outcome. However, previous techniques to evaluate NVC required invasive procedures. Retinal vessels may represent an alternative option for non-invasive assessment of NVC. Methods A prototype of an adapted retinal vessel analyzer was used to assess retinal vessel diameter in mice. Dynamic vessel analysis (DVA) included an application of monochromatic flicker light impulses in predefined frequencies for evaluating NVC. All retinae were harvested after DVA and electroretinograms were performed. Results A total of 104 retinal scans were conducted in 21 male mice (90 scans). Quantitative arterial recordings were feasible only in a minority of animals, showing an emphasized reaction to flicker light impulses (8 mice; 14 scans). A characteristic venous response to flicker light, however, could observed in the majority of animals. Repeated measurements resulted in a significant decrease of baseline venous diameter (7 mice; 7 scans, p < 0.05). Ex-vivo electroretinograms, performed after in-vivo DVA, demonstrated a significant reduction of transretinal signaling in animals with repeated DVA (n = 6, p < 0.001). Conclusions To the best of our knowledge, this is the first non-invasive study assessing murine retinal vessel response to flicker light with characteristic changes in NVC. The imaging system can be used for basic research and enables the investigation of retinal vessel dimension and function in control mice and genetically modified animals.},
  language  = {en}
}
@article{AboulnagaZouSelmeretal.2018,
  author    = {Aboulnaga, E. A. and Zou, H. and Selmer, Thorsten and Xian, M.},
  title     = {Development of a plasmid-based, tunable, tolC-derived expression system for application in Cupriavidus necator H16},
  series = {Journal of Biotechnology},
  volume    = {274},
  journal   = {Journal of Biotechnology},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0168-1656},
  doi       = {10.1016/j.jbiotec.2018.03.007},
  pages     = {15 -- 27},
  year      = {2018},
  abstract  = {Cupriavidus necator H16 gains increasing attention in microbial research and biotechnological application due to its diverse metabolic features. Here we present a tightly controlled gene expression system for C. necator including the pBBR1-vector that contains hybrid promoters originating from C. necator native tolC-promoter in combination with a synthetic tetO-operator. The expression of the reporter gene from these plasmids relies on the addition of the exogenous inducer doxycycline (dc). The novel expression system offers a combination of advantageous features as; (i) high and dose-dependent recombinant protein production, (ii) tight control with a high dynamic range (On/Off ratio), which makes it applicable for harmful pathways or for toxic protein production, (iii) comparable cheap inducer (doxycycline, dc), (iv) effective at low inducer concentration, that makes it useful for large scale application, (v) rapid, diffusion controlled induction, and (vi) the inducer does not interfere within the cell metabolism. As applications of the expression system in C. necator H16, the growth ability on glycerol was enhanced by constitutively expressing the E. coli glpk gene-encoding for glycerol kinase. Likewise, we used the system to overcome the expression toxicity of mevalonate pathway in C. necator H16. With this system, the mevalonate-genes were successfully introduced in the host and the recombinant strains could produce about 200 mg/l mevalonate.},
  language  = {en}
}