@article{FalkenbergBottBongaertsetal.2022,
  author    = {Falkenberg, Fabian and Bott, Michael and Bongaerts, Johannes and Siegert, Petra},
  title     = {Phylogenetic survey of the subtilase family and a data-mining-based search for new subtilisins from Bacillaceae},
  series = {Frontiers in Microbiology},
  volume    = {2022},
  journal   = {Frontiers in Microbiology},
  number    = {13},
  publisher = {Frontiers},
  address   = {Lausanne},
  issn      = {1664-302X},
  doi       = {10.3389/fmicb.2022.1017978},
  pages     = {Artikel 13:1017978},
  year      = {2022},
  abstract  = {The subtilase family (S8), a member of the clan SB of serine proteases are ubiquitous in all kingdoms of life and fulfil different physiological functions. Subtilases are divided in several groups and especially subtilisins are of interest as they are used in various industrial sectors. Therefore, we searched for new subtilisin sequences of the family Bacillaceae using a data mining approach. The obtained 1,400 sequences were phylogenetically classified in the context of the subtilase family. This required an updated comprehensive overview of the different groups within this family. To fill this gap, we conducted a phylogenetic survey of the S8 family with characterised holotypes derived from the MEROPS database. The analysis revealed the presence of eight previously uncharacterised groups and 13 subgroups within the S8 family. The sequences that emerged from the data mining with the set filter parameters were mainly assigned to the subtilisin subgroups of true subtilisins, high-alkaline subtilisins, and phylogenetically intermediate subtilisins and represent an excellent source for new subtilisin candidates.},
  language  = {en}
}
@book{Lauth2023,
  author    = {Lauth, Jakob},
  title     = {Physical chemistry in a nutshell: Basics for engineers and scientists},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {978-3-662-67636-3 (Softcover)},
  doi       = {10.1007/978-3-662-67637-0},
  pages     = {XIII, 248 Seiten},
  year      = {2023},
  abstract  = {This book is based on a multimedia course for biological and chemical engineers, which is designed to trigger students' curiosity and initiative. A solid basic knowledge of thermodynamics and kinetics is necessary for understanding many technical, chemical, and biological processes. The one-semester basic lecture course was divided into 12 workshops (chapters). Each chapter covers a practically relevant area of physical chemistry and contains the following didactic elements that make this book particularly exciting and understandable: - Links to Videos at the start of each chapter as preparation for the workshop - Key terms (in bold) for further research of your own - Comprehension questions and calculation exercises with solutions as learning checks - Key illustrations as simple, easy-to-replicate blackboard pictures Humorous cartoons for each workshop (by Faelis) additionally lighten up the text and facilitate the learning process as a mnemonic. To round out the book, the appendix includes a summary of the most popular experiments in basic physical chemistry courses, as well as suggestions for designing workshops with exhibits, experiments, and "questions of the day." Suitable for students minoring in chemistry; chemistry majors are sure to find this slimmed-down, didactically valuable book helpful as well. The book is excellent for self-study.},
  language  = {en}
}
@article{AggarwalSinghSinghetal.2011,
  author    = {Aggarwal, Prerna and Singh, Virendra and Singh, Arjun and Scherer, Ulrich W. and Singh, Tejvir and Singla, Madan L. and Srivastava, Alok},
  title     = {Physico-chemical transformations in swift heavy ion modified poly(ethyleneterephthalate)},
  series = {Radiation Physics and Chemistry},
  journal   = {Radiation Physics and Chemistry},
  publisher = {Pergamon Press},
  address   = {Oxford},
  isbn      = {0969-806X},
  pages     = {1 -- 28},
  year      = {2011},
  language  = {en}
}
@article{SmithBaumannWilsonetal.1987,
  author    = {Smith, Walker O. and Baumann, Marcus and Wilson, David L. and Aletsee, Ludwig},
  title     = {Phytoplankton biomass and productivity in the marginal ice zone of the Fram Strait during summer 1984},
  series = {Journal of geophysical research},
  volume    = {Vol. 92},
  journal   = {Journal of geophysical research},
  number    = {Iss. C7},
  issn      = {2156-2202 (E-Journal); 2169-9291 (E-Journal); 0148-0227 (Print); 2169-9275 (Print)},
  pages     = {6777 -- 6786},
  year      = {1987},
  language  = {en}
}
@article{BaumannGoeyensSemenehetal.1998,
  author    = {Baumann, Marcus and Goeyens, L. and Semeneh, M. and Elskens, M.},
  title     = {Phytoplankton nutrient utilisation and nutrient signature in the Southern Ocean / Goeyens, L. ; Semeneh, M. ; Baumann, M.E.M. ; Elskens, M. ; Shopova, D. ; Dehairs, F.},
  series = {Journal of Marine Systems. 17 (1998), H. 1-4},
  journal   = {Journal of Marine Systems. 17 (1998), H. 1-4},
  isbn      = {0924-7963},
  pages     = {143 -- 157},
  year      = {1998},
  language  = {en}
}
@article{BiselliZengDinteretal.1997,
  author    = {Biselli, Manfred and Zeng, Steffen and Dinter, Andre and Eisenkr{\"a}tzer, Detlef},
  title     = {Pilot Scale Expression and Purification of Soluble Protein A Tagged \&\#946;1,6N-Acetylglucosaminyltransferase in CHO Cells / Zeng, Steffen ; Dinter, Andre ; Eisenkr{\"a}tzer, Detlef ; Biselli, Manfred ; Wandrey, Christian ; Berger, Eric G.},
  series = {Biochemical and Biophysical Research Communications. 237 (1997), H. 3},
  journal   = {Biochemical and Biophysical Research Communications. 237 (1997), H. 3},
  isbn      = {0006-291X},
  pages     = {653 -- 658},
  year      = {1997},
  language  = {en}
}
@article{BaumannHircheKattneretal.1991,
  author    = {Baumann, Marcus and Hirche, H.-J. and Kattner, G. and Gradinger, R.},
  title     = {Plankton distribution and the impact of copepod grazing on primary production in Fram Strait, Greenland Sea / Hirche, H.-J. ; Baumann, M.E.M. ; Kattner, G.; Gradinger, R.},
  series = {Journal of Marine Systems. 2 (1991), H. 3-4},
  journal   = {Journal of Marine Systems. 2 (1991), H. 3-4},
  isbn      = {0924-7963},
  pages     = {477 -- 494},
  year      = {1991},
  language  = {en}
}
@article{MichalakNacerddinePietersenetal.2013,
  author    = {Michalak, Ewa Malgorzata and Nacerddine, Karim and Pietersen, Alexandra and Beuger, Vincent and Pawlitzky, Inka and Cornelissen-Steijger, Paulien and Wientjens, Ellen and Tanger, Ellen and Seibler, Jost and Lohuizen, Maarten van and Jonkers, Jos},
  title     = {Polycomb group gene Ezh2 regulates mammary gland morphogenesis and maintains the luminal progenitor pool},
  series = {Stem Cells},
  volume    = {Vol 31},
  journal   = {Stem Cells},
  number    = {9},
  publisher = {Oxford University Press},
  address   = {Oxford},
  issn      = {1549-4918},
  doi       = {10.1002/stem.1437},
  pages     = {1910 -- 1920},
  year      = {2013},
  language  = {en}
}
@article{MangKricheldorfJonte1985,
  author    = {Mang, Thomas and Kricheldorf, Hans R. and Jont{\´e}, J. Michael},
  title     = {Polylactones, 2. Copolymerization of glycolide with \&\#946;-propiolactone, \&\#967;-butyrolactone or \&\#948;-valerolactone / Kricheldorf, Hans R. ; Mang, Thomas ; Jont{\´e}, J. Michael},
  series = {Die makromolekulare Chemie. 186 (1985), H. 5},
  journal   = {Die makromolekulare Chemie. 186 (1985), H. 5},
  isbn      = {1022-1352},
  pages     = {955 -- 976},
  year      = {1985},
  language  = {en}
}
@article{MangKricheldorfJonte1984,
  author    = {Mang, Thomas and Kricheldorf, Hans R. and Jont{\´e}, J. Michael},
  title     = {Polylactones. 1. Copolymerizations of glycolide and \&beta-caprolactone / Kricheldorf, Hans R. ; Mang, Thomas ; Jont{\´e}, J. Michael},
  series = {Macromolecules. 17 (1984), H. 10},
  journal   = {Macromolecules. 17 (1984), H. 10},
  isbn      = {0024-9297},
  pages     = {2173 -- 2181},
  year      = {1984},
  language  = {en}
}
@article{Mang2004,
  author    = {Mang, Thomas},
  title     = {Polymer Magnetic Particles for Isolating Biomolecules, Especially Nucleic Acids},
  series = {Biomedizinische Technik = Biomedical Engineering. 49 (2004), H. 2},
  journal   = {Biomedizinische Technik = Biomedical Engineering. 49 (2004), H. 2},
  isbn      = {0013-5585},
  pages     = {1008 -- 1009},
  year      = {2004},
  language  = {en}
}
@article{OosterhuisOehlschlaegerBergetal.2011,
  author    = {Oosterhuis, Koen and {\"O}hlschl{\"a}ger, Peter and Berg, Joost H. van den and Toebes, Mireille and Gomez, Raquel and Schumacher, Ton N. and Haanen, John B.},
  title     = {Preclinical development of highly effective and safe DNA vaccines directed against HPV 16 E6 and E7},
  series = {International Journal of Cancer},
  volume    = {129},
  journal   = {International Journal of Cancer},
  number    = {2},
  publisher = {Wiley},
  address   = {Weinheim},
  isbn      = {1097-0215},
  pages     = {397 -- 406},
  year      = {2011},
  language  = {en}
}
@article{HenkenOosterhuisOehlschlaegeretal.2012,
  author    = {Henken, F. E. and Oosterhuis, K. and {\"O}hlschl{\"a}ger, Peter and Bosch, L. and Hooijberg, E. and Haanen, J. B. A. G. and Steenbergen, R. D. M.},
  title     = {Preclinical safety evaluation of DNA vaccines encoding modified HPV16 E6 and E7},
  series = {Vaccine},
  volume    = {30},
  journal   = {Vaccine},
  number    = {28},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0264-410X},
  doi       = {10.1016/j.vaccine.2012.04.013},
  pages     = {4259 -- 4266},
  year      = {2012},
  abstract  = {Persistent infection with high-risk human papillomaviruses (hrHPV) can result in the formation of anogenital cancers. As hrHPV proteins E6 and E7 are required for cancer initiation and maintenance, they are ideal targets for immunotherapeutic interventions. Previously, we have described the development of DNA vaccines for the induction of HPV16 E6 and E7 specific T cell immunity. These vaccines consist of 'gene-shuffled' (SH) versions of HPV16 E6 and E7 that were fused to Tetanus Toxin Fragment C domain 1 (TTFC) and were named TTFC-E6SH and TTFC-E7SH. Gene-shuffling was performed to avoid the risk of inducing malignant transformation at the vaccination site. Here, we describe the preclinical safety evaluation of these candidate vaccines by analysis of their transforming capacity in vitro using established murine fibroblasts (NIH 3T3 cells) and primary human foreskin keratinocytes (HFKs). We demonstrate that neither ectopic expression of TTFC-E6SH and TTFC-E7SH alone or in combination enabled NIH 3T3 cells to form colonies in soft agar. In contrast, expression of HPV16 E6WT and E7WT alone or in combination resulted in effective transformation. Similarly, retroviral transduction of HFKs from three independent donors with both TTFC-E6SH and TTFC-E7SH alone or in combination did not show any signs of immortalization. In contrast, the combined expression of E6WT and E7WT induced immortalization in HFKs from all donors. Based on these results we consider it justified to proceed to clinical evaluation of DNA vaccines encoding TTFC-E6SH and TTFC-E7SH in patients with HPV16 associated (pre)malignancies.},
  language  = {en}
}
@book{LauthHarreusGoetzetal.1999,
  author    = {Lauth, Jakob and Harreus, Albrecht and G{\"o}tz, Norbert and Rang, Harald [u.a.]},
  title     = {Preparation O-(2-Hydroxyalkyl)Oximes = of Verfahren zur Herstellung von O-(2-Hydroxy)Oximen : Europ{\"a}ische Patentschrift EP0775107B1 ; Ver{\"o}ffentlichungstag im Patentblatt: 18.11.1999 / Anmelder: BASF AG, 67063 Ludwigshafen. Erfinder: Albrecht Harreus ; Norbert G{\"o}tz ; Harald Rang ... G{\"u}nter Lauth},
  publisher = {Europ{\"a}isches Patentamt},
  address   = {[M{\"u}nchen u.a.]},
  pages     = {8 S. : graph. Darst.},
  year      = {1999},
  language  = {en}
}
@misc{LauthWolfBurkhart1998,
  author    = {Lauth, Jakob and Wolf, Gerhard and Burkhart, Bernd},
  title     = {Preparation of alkoxylation products in the presence of mixed hydroxides modified with additives : United States Patent ; patent number 5,741,947 ; date of patent: Apr. 21, 1998 / assignee: BASF Aktiengesellschaft. Inventors: Gerhard Wolf ; Bernd Burkhart ; Guenter Lauth ...},
  publisher = {[United States Trademark and Patent Office]},
  address   = {[Alexandria, VA]},
  pages     = {8 S.},
  year      = {1998},
  language  = {en}
}
@misc{LauthMuellerHoelderich1994,
  author    = {Lauth, Jakob and M{\"u}ller, Ulrich and Hoelderich, Wolfgang},
  title     = {Preparation of aluminophosphates and silicoaluminophosphates having the AEL structure using 1,2-bis-( 4-pyridyl)-ethane : United States Patent ; patent number 5,324,493 ; date of patent: Jun. 28, 1994 / assignee: BASF Aktiengesellschaft. Inventors: Ulrich Mueller ; Wolfgang Hoelderich ; Guenter Lauth},
  publisher = {[United States Trademark and Patent Office]},
  address   = {[Alexandria, VA]},
  pages     = {6 S. : Ill.},
  year      = {1994},
  language  = {en}
}
@misc{LauthDingerdissenHenne1998,
  author    = {Lauth, Jakob and Dingerdissen, Uwe and Henne, Andreas},
  title     = {Preparation of amines : United States Patent ; patent number 5,817,871 ; date of patent: Oct. 6, 1998 / Assignee: BASF Aktiengesellschaft. Inventors: Uwe Dingerdissen ; Gunter Lauth ; Andreas Henne ....},
  publisher = {[United States Trademark and Patent Office]},
  address   = {[Alexandria, VA]},
  pages     = {6 S. : Ill.},
  year      = {1998},
  language  = {en}
}
@misc{LauthDingerdissenTruebenbachetal.1997,
  author    = {Lauth, Jakob and Dingerdissen, Uwe and Tr{\"u}benbach, Peter and Steuerle, Ulrich},
  title     = {Preparation of aziridines : United States Patent ; patent number 5,693,825 ; date of patent: Dec. 2, 1997 / assignee: BASF Aktiengesellschaft. Inventors: Uwe Dingerdissen ; Gunter Lauth ; Peter Trubenbach ; Ulrich Steuerle},
  publisher = {United States Patent and Trademark Office},
  address   = {[Alexandria, VA]},
  pages     = {6 S. : Ill.},
  year      = {1997},
  language  = {en}
}
@article{BiselliSchmidWandrey1988,
  author    = {Biselli, Manfred and Schmid, Georg and Wandrey, Christian},
  title     = {Preparation of cellodextrins and isolation of oligomeric side components and their characterization / Schmid, Georg ; Biselli, Manfred ; Wandrey, Christian},
  series = {Analytical Biochemistry. 175 (1988)},
  journal   = {Analytical Biochemistry. 175 (1988)},
  isbn      = {0003-2697},
  pages     = {573 -- 583},
  year      = {1988},
  language  = {en}
}
@misc{LauthHarreusGoetzetal.1997,
  author    = {Lauth, Jakob and Harreus, Albrecht and Goetz, Norbert and Rang, Harald},
  title     = {Preparation of O-(2-hydroxyalkyl) oximes : [South African Patent ] publication number: ZA9506402 ; publication date: 1997-02-03 / applicant: BASF AG. Inventor: Harreus, Albrecht ; Goetz, Norbert ; Rang, Harald .... Lauth, Guenter ...},
  publisher = {[South African Companies and Intellectual Property Registration Office]},
  address   = {[Pretoria]},
  year      = {1997},
  language  = {en}
}