@article{SchererHoerHertel1998, author = {Scherer, Ulrich W. and H{\"o}r, G. and Hertel, A.}, title = {Positronen-Emissions-Tomographie des Herzens / G. H{\"o}r, A. Hertel, U. W. Scherer}, series = {Herzerkrankungen und Interventionsm{\"o}glichkeiten / F. Unger [Hrsg.]}, journal = {Herzerkrankungen und Interventionsm{\"o}glichkeiten / F. Unger [Hrsg.]}, publisher = {Springer}, address = {Berlin}, isbn = {3-540-62916-5}, pages = {236 -- 263}, year = {1998}, language = {de} } @article{OosterhuisOehlschlaegerBergetal.2011, author = {Oosterhuis, Koen and {\"O}hlschl{\"a}ger, Peter and Berg, Joost H. van den and Toebes, Mireille and Gomez, Raquel and Schumacher, Ton N. and Haanen, John B.}, title = {Preclinical development of highly effective and safe DNA vaccines directed against HPV 16 E6 and E7}, series = {International Journal of Cancer}, volume = {129}, journal = {International Journal of Cancer}, number = {2}, publisher = {Wiley}, address = {Weinheim}, isbn = {1097-0215}, pages = {397 -- 406}, year = {2011}, language = {en} } @article{HenkenOosterhuisOehlschlaegeretal.2012, author = {Henken, F. E. and Oosterhuis, K. and {\"O}hlschl{\"a}ger, Peter and Bosch, L. and Hooijberg, E. and Haanen, J. B. A. G. and Steenbergen, R. D. M.}, title = {Preclinical safety evaluation of DNA vaccines encoding modified HPV16 E6 and E7}, series = {Vaccine}, volume = {30}, journal = {Vaccine}, number = {28}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0264-410X}, doi = {10.1016/j.vaccine.2012.04.013}, pages = {4259 -- 4266}, year = {2012}, abstract = {Persistent infection with high-risk human papillomaviruses (hrHPV) can result in the formation of anogenital cancers. As hrHPV proteins E6 and E7 are required for cancer initiation and maintenance, they are ideal targets for immunotherapeutic interventions. Previously, we have described the development of DNA vaccines for the induction of HPV16 E6 and E7 specific T cell immunity. These vaccines consist of 'gene-shuffled' (SH) versions of HPV16 E6 and E7 that were fused to Tetanus Toxin Fragment C domain 1 (TTFC) and were named TTFC-E6SH and TTFC-E7SH. Gene-shuffling was performed to avoid the risk of inducing malignant transformation at the vaccination site. Here, we describe the preclinical safety evaluation of these candidate vaccines by analysis of their transforming capacity in vitro using established murine fibroblasts (NIH 3T3 cells) and primary human foreskin keratinocytes (HFKs). We demonstrate that neither ectopic expression of TTFC-E6SH and TTFC-E7SH alone or in combination enabled NIH 3T3 cells to form colonies in soft agar. In contrast, expression of HPV16 E6WT and E7WT alone or in combination resulted in effective transformation. Similarly, retroviral transduction of HFKs from three independent donors with both TTFC-E6SH and TTFC-E7SH alone or in combination did not show any signs of immortalization. In contrast, the combined expression of E6WT and E7WT induced immortalization in HFKs from all donors. Based on these results we consider it justified to proceed to clinical evaluation of DNA vaccines encoding TTFC-E6SH and TTFC-E7SH in patients with HPV16 associated (pre)malignancies.}, language = {en} } @book{LauthHarreusGoetzetal.1999, author = {Lauth, Jakob and Harreus, Albrecht and G{\"o}tz, Norbert and Rang, Harald [u.a.]}, title = {Preparation O-(2-Hydroxyalkyl)Oximes = of Verfahren zur Herstellung von O-(2-Hydroxy)Oximen : Europ{\"a}ische Patentschrift EP0775107B1 ; Ver{\"o}ffentlichungstag im Patentblatt: 18.11.1999 / Anmelder: BASF AG, 67063 Ludwigshafen. Erfinder: Albrecht Harreus ; Norbert G{\"o}tz ; Harald Rang ... G{\"u}nter Lauth}, publisher = {Europ{\"a}isches Patentamt}, address = {[M{\"u}nchen u.a.]}, pages = {8 S. : graph. Darst.}, year = {1999}, language = {en} } @misc{LauthWolfBurkhart1998, author = {Lauth, Jakob and Wolf, Gerhard and Burkhart, Bernd}, title = {Preparation of alkoxylation products in the presence of mixed hydroxides modified with additives : United States Patent ; patent number 5,741,947 ; date of patent: Apr. 21, 1998 / assignee: BASF Aktiengesellschaft. Inventors: Gerhard Wolf ; Bernd Burkhart ; Guenter Lauth ...}, publisher = {[United States Trademark and Patent Office]}, address = {[Alexandria, VA]}, pages = {8 S.}, year = {1998}, language = {en} } @misc{LauthMuellerHoelderich1994, author = {Lauth, Jakob and M{\"u}ller, Ulrich and Hoelderich, Wolfgang}, title = {Preparation of aluminophosphates and silicoaluminophosphates having the AEL structure using 1,2-bis-( 4-pyridyl)-ethane : United States Patent ; patent number 5,324,493 ; date of patent: Jun. 28, 1994 / assignee: BASF Aktiengesellschaft. Inventors: Ulrich Mueller ; Wolfgang Hoelderich ; Guenter Lauth}, publisher = {[United States Trademark and Patent Office]}, address = {[Alexandria, VA]}, pages = {6 S. : Ill.}, year = {1994}, language = {en} } @misc{LauthDingerdissenHenne1998, author = {Lauth, Jakob and Dingerdissen, Uwe and Henne, Andreas}, title = {Preparation of amines : United States Patent ; patent number 5,817,871 ; date of patent: Oct. 6, 1998 / Assignee: BASF Aktiengesellschaft. Inventors: Uwe Dingerdissen ; Gunter Lauth ; Andreas Henne ....}, publisher = {[United States Trademark and Patent Office]}, address = {[Alexandria, VA]}, pages = {6 S. : Ill.}, year = {1998}, language = {en} } @misc{LauthDingerdissenTruebenbachetal.1997, author = {Lauth, Jakob and Dingerdissen, Uwe and Tr{\"u}benbach, Peter and Steuerle, Ulrich}, title = {Preparation of aziridines : United States Patent ; patent number 5,693,825 ; date of patent: Dec. 2, 1997 / assignee: BASF Aktiengesellschaft. Inventors: Uwe Dingerdissen ; Gunter Lauth ; Peter Trubenbach ; Ulrich Steuerle}, publisher = {United States Patent and Trademark Office}, address = {[Alexandria, VA]}, pages = {6 S. : Ill.}, year = {1997}, language = {en} } @article{BiselliSchmidWandrey1988, author = {Biselli, Manfred and Schmid, Georg and Wandrey, Christian}, title = {Preparation of cellodextrins and isolation of oligomeric side components and their characterization / Schmid, Georg ; Biselli, Manfred ; Wandrey, Christian}, series = {Analytical Biochemistry. 175 (1988)}, journal = {Analytical Biochemistry. 175 (1988)}, isbn = {0003-2697}, pages = {573 -- 583}, year = {1988}, language = {en} } @misc{LauthHarreusGoetzetal.1997, author = {Lauth, Jakob and Harreus, Albrecht and Goetz, Norbert and Rang, Harald}, title = {Preparation of O-(2-hydroxyalkyl) oximes : [South African Patent ] publication number: ZA9506402 ; publication date: 1997-02-03 / applicant: BASF AG. Inventor: Harreus, Albrecht ; Goetz, Norbert ; Rang, Harald .... Lauth, Guenter ...}, publisher = {[South African Companies and Intellectual Property Registration Office]}, address = {[Pretoria]}, year = {1997}, language = {en} } @misc{Lauth1995, author = {Lauth, Jakob}, title = {Preparation of O-(2-hydroxyalkyl) oximes : patent application CA 2196452 ; filing date: 1995-07-28 ; national entry: 1997-01-30 / applicants: BASF Aktiengesellschaft. Inventors: Harreus, Albrecht ; Gotz, Norbert ; Rang, Harald ... Lauth, Guenther ...}, publisher = {Canadian International Property Office}, address = {[Gatineau, Quebec]}, pages = {15 S. : Ill.}, year = {1995}, language = {en} } @article{KotterHammon1986, author = {Kotter, Michael and Hammon, U.}, title = {Preparation of pellets with well-defined pore structure / U. Hammon ; A. Kotter}, series = {International chemical engineering. 26 (1986), H. 4}, journal = {International chemical engineering. 26 (1986), H. 4}, isbn = {0020-6318}, pages = {563 -- 573}, year = {1986}, language = {en} } @article{NaithaniKlostermeyerLangeetal.1971, author = {Naithani, V. K and Klostermeyer, Henning and Lange, H. R. and [u.a.], and Berndt, Heinz and [u.a.],}, title = {Preparation of peptide derivatives for porcine proinsulin-synthesis}, series = {Biological Chemistry}, volume = {352}, journal = {Biological Chemistry}, number = {1}, publisher = {De Gruyter}, issn = {1437-4315}, doi = {10.1515/bchm2.1971.352.1.1}, pages = {2 -- 3}, year = {1971}, language = {en} } @unpublished{GreinerJerominSitholeetal.2023, author = {Greiner, Lasse and Jeromin, G{\"u}nter Erich and Sithole, Patience and Petersen, Soenke}, title = {Preprint: Studies on the enzymatic reduction of levulinic acid using Chiralidon-R and Chiralidon-S}, series = {ChemRxiv}, journal = {ChemRxiv}, doi = {10.26434/chemrxiv-2023-jlvcv}, pages = {13 Seiten}, year = {2023}, abstract = {The enzymatic reduction of levulinic acid by the chiral catalysts Chiralidon-R and Chiralidon-S which are commercially available superabsorbed alcohol dehydrogenases is described. The Chiralidon®-R/S reduces the levulinic acid to the (R,S)-4-hydroxy valeric acid and the (R)- or (S)- gamma-valerolactone.}, language = {en} } @article{PrielmeierWoznyjLuedemann1984, author = {Prielmeier, Franz and Woznyj, M. and L{\"u}demann, H.-D.}, title = {Pressure Dependence of the Melting and Self Diffusion in 2,2-Dimethylpropane, 2,2-Dimethylpropionitrile, and 2-Methylpropanol-2 / M. Woznyj, F. X. Prielmeier, H.-D. L{\"u}demann}, series = {Zeitschrift f{\"u}r Naturforschung A, Journal of Physical Sciences. 39 (1984)}, journal = {Zeitschrift f{\"u}r Naturforschung A, Journal of Physical Sciences. 39 (1984)}, isbn = {0932-0784}, pages = {800}, year = {1984}, language = {en} } @article{PrielmeierLangLuedemann1984, author = {Prielmeier, Franz and Lang, E. W. and L{\"u}demann, H.-D.}, title = {Pressure dependence of the self-diffusion in liquid trifluoromethane / F. X. Prielmeier; E. W. Lang; H.-D. L{\"u}demann}, series = {Molecular Physics. 52 (1984), H. 5}, journal = {Molecular Physics. 52 (1984), H. 5}, isbn = {0026-8976}, pages = {1105 -- 1113}, year = {1984}, language = {en} } @inproceedings{MoehringWulfhorstRothetal.2016, author = {M{\"o}hring, S. and Wulfhorst, H. and Roth, J. and Tippk{\"o}tter, Nils}, title = {Pretreatment strategies for lignocellulosic biomass}, series = {New frontiers of biotech-processes (Himmelfahrtstagung) : 02-04 May 2016, Rhein-Mosel-Halle, Koblenz/Germany}, booktitle = {New frontiers of biotech-processes (Himmelfahrtstagung) : 02-04 May 2016, Rhein-Mosel-Halle, Koblenz/Germany}, publisher = {DECHEMA}, address = {Frankfurt am Main}, pages = {131}, year = {2016}, language = {en} } @inproceedings{Baumann1989, author = {Baumann, Marcus}, title = {Primary production and phytoplankton growth in the marginal ice zone of the Fram Strait and the interpretation of the field data with autecological experiments (Abstract)}, series = {Oceanography and biology of Arctic seas : selected papers from the ICES Symposium on Marine Sciences of the Arctic and Subarctic Regions, held in Santander, 28 - 30 September 1987. (Rapports et proc{\`e}s-verbaux des r{\´e}unions / Conseil International pour l'Exploration de la Mer ; 188)}, booktitle = {Oceanography and biology of Arctic seas : selected papers from the ICES Symposium on Marine Sciences of the Arctic and Subarctic Regions, held in Santander, 28 - 30 September 1987. (Rapports et proc{\`e}s-verbaux des r{\´e}unions / Conseil International pour l'Exploration de la Mer ; 188)}, editor = {Hempel, G.}, publisher = {International Council for the Exploration of the Sea}, address = {Copenhagen}, organization = {Symposium on Marine Sciences of the Arctic and Subarctic Regions <1987, Santander>}, pages = {128}, year = {1989}, language = {en} } @article{KotterRiekertSimoncic1986, author = {Kotter, Michael and Riekert, Lothar and Simoncic, V.}, title = {Pristup sintezi industrijskih katalizatora}, series = {Kemija u industriji : casopis kemicara i tehnologa Jugoslavije. 35 (1986)}, journal = {Kemija u industriji : casopis kemicara i tehnologa Jugoslavije. 35 (1986)}, isbn = {0022-9830}, pages = {79 -- 86}, year = {1986}, language = {de} } @article{ElbersMuratyan1991, author = {Elbers, Gereon and Muratyan, Simone}, title = {Problematik verkehrsbezogener Außenluftmessungen von Partikeln (Dieselruß)}, series = {+ Krebserzeugende Stoffe in der Umwelt : Herkunft, Messung, Risiko, Minimierung ; Kolloquium Mannheim, 23. bis 25. April 1991 / Kommission Reinhaltung der Luft im VDI und DIN}, journal = {+ Krebserzeugende Stoffe in der Umwelt : Herkunft, Messung, Risiko, Minimierung ; Kolloquium Mannheim, 23. bis 25. April 1991 / Kommission Reinhaltung der Luft im VDI und DIN}, publisher = {VDI-Verl.}, address = {D{\"u}sseldorf}, isbn = {3-18-090888-2}, pages = {143}, year = {1991}, language = {de} }