@article{JansenBehbahaniLaumenetal.2010, author = {Jansen, S. V. and Behbahani, Mehdi and Laumen, M. and Kaufmann, T. and Hormes, M. and Behr, M. and Schmitz-Rode, T. and Steinseifer, U.}, title = {Investigation of Steady Flow Through a Realistic Model of the Thoracic Human Aorta Using 3D Stereo PIV and CFD-Simulation}, series = {ASAIO Journal}, volume = {56}, journal = {ASAIO Journal}, number = {2}, publisher = {Lippincott Williams \& Wilkins}, address = {Philadelphia}, doi = {10.1097/01.mat.0000369377.65122.a3}, pages = {98}, year = {2010}, language = {en} } @article{BehbahaniNamWalugaetal.2010, author = {Behbahani, Mehdi and Nam, J. and Waluga, C. and Behr, M. and Pasquali, M. and Mottaghy, K.}, title = {Modeling and Numerical Analysis of Platelet Activation, Adhesion and Aggregation in Artificial Organs}, volume = {56}, number = {2}, publisher = {Lippincott Williams \& Wilkins}, address = {Philadelphia}, doi = {10.1097/01.mat.0000369377.65122.a3}, pages = {85}, year = {2010}, language = {en} } @book{Pettrak2014, author = {Pettrak, J{\"u}rgen}, title = {Nutzung nachwachsender Rohstoffe bei der Herstellung thermoplastischer Elastomere aus Folgeprodukten der Olefinmetathese}, publisher = {Attenkofer}, address = {Straubing}, isbn = {978-3-942742-35-1}, pages = {147 Seiten}, year = {2014}, language = {de} } @article{BaroudWuBohneretal.2003, author = {Baroud, Gamal and Wu, J.Z. and Bohner, M and Sponagel, Stefan and Steffen, T.}, title = {How to determine the permeability for cement infiltration into osteoporotic cancellous bone}, series = {Medical Engineering \& Physics. 25 (2003), H. 4}, journal = {Medical Engineering \& Physics. 25 (2003), H. 4}, issn = {1350-4533}, pages = {283 -- 288}, year = {2003}, abstract = {Cement augmentation is an emerging surgical procedure in which bone cement is used to infiltrate and reinforce osteoporotic vertebrae. Although this infiltration procedure has been widely applied, it is performed empirically and little is known about the flow characteristics of cement during the injection process. We present a theoretical and experimental approach to investigate the intertrabecular bone permeability during the infiltration procedure. The cement permeability was considered to be dependent on time, bone porosity, and cement viscosity in our analysis. In order to determine the time-dependent permeability, ten cancellous bone cores were harvested from osteoporotic vertebrae, infiltrated with acrylic cement at a constant flow rate, and the pressure drop across the cores during the infiltration was measured. The viscosity dependence of the permeability was determined based on published experimental data. The theoretical model for the permeability as a function of bone porosity and time was then fit to the testing data. Our findings suggest that the intertrabecular bone permeability depends strongly on time. For instance, the initial permeability (60.89 mm4/N.s) reduced to approximately 63\% of its original value within 18 seconds. This study is the first to analyze cement flow through osteoporotic bone. The theoretical and experimental models provided in this paper are generic. Thus, they can be used to systematically study and optimize the infiltration process for clinical practice.}, subject = {Osteoporose}, language = {en} } @article{RhodenBallGrajewskietal.2023, author = {Rhoden, Imke and Ball, Christopher Stephen and Grajewski, Matthias and Kuckshinrich, Wilhelm}, title = {Reverse engineering of stakeholder preferences - A multi-criteria assessment of the German passenger car sector}, series = {Renewable and Sustainable Energy Reviews}, volume = {181}, journal = {Renewable and Sustainable Energy Reviews}, number = {July 2023}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1364-0321}, doi = {10.1016/j.rser.2023.113352}, pages = {Article number: 113352}, year = {2023}, abstract = {Germany is a frontrunner in setting frameworks for the transition to a low-carbon system. The mobility sector plays a significant role in this shift, affecting different people and groups on multiple levels. Without acceptance from these stakeholders, emission targets are out of reach. This research analyzes how the heterogeneous preferences of various stakeholders align with the transformation of the mobility sector, looking at the extent to which the German transformation paths are supported and where stakeholders are located. Under the research objective of comparing stakeholders' preferences to identify which car segments require additional support for a successful climate transition, a status quo of stakeholders and car performance criteria is the foundation for the analysis. Stakeholders' hidden preferences hinder the derivation of criteria weightings from stakeholders; therefore, a ranking from observed preferences is used. This study's inverse multi-criteria decision analysis means that weightings can be predicted and used together with a recalibrated performance matrix to explore future preferences toward car segments. Results show that stakeholders prefer medium-sized cars, with the trend pointing towards the increased potential for alternative propulsion technologies and electrified vehicles. These insights can guide the improved targeting of policy supporting the energy and mobility transformation. Additionally, the method proposed in this work can fully handle subjective approaches while incorporating a priori information. A software implementation of the proposed method completes this work and is made publicly available.}, language = {en} } @article{VoegeleJosyabhatlaBalletal.2023, author = {V{\"o}gele, Stefan and Josyabhatla, Vishnu Teja and Ball, Christopher Stephen and Rhoden, Imke and Grajewski, Matthias and R{\"u}bbelke, Dirk and Kuckshinrichs, Wilhelm}, title = {Robust assessment of energy scenarios from stakeholders' perspectives}, series = {Energy}, journal = {Energy}, number = {In Press, Article 128326}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-6785 (Online)}, doi = {10.1016/j.energy.2023.128326}, year = {2023}, abstract = {Using scenarios is vital in identifying and specifying measures for successfully transforming the energy system. Such transformations can be particularly challenging and require the support of a broader set of stakeholders. Otherwise, there will be opposition in the form of reluctance to adopt the necessary technologies. Usually, processes for considering stakeholders' perspectives are very time-consuming and costly. In particular, there are uncertainties about how to deal with modifications in the scenarios. In principle, new consulting processes will be required. In our study, we show how multi-criteria decision analysis can be used to analyze stakeholders' attitudes toward transition paths. Since stakeholders differ regarding their preferences and time horizons, we employ a multi-criteria decision analysis approach to identify which stakeholders will support or oppose a transition path. We provide a flexible template for analyzing stakeholder preferences toward transition paths. This flexibility comes from the fact that our multi-criteria decision aid-based approach does not involve intensive empirical work with stakeholders. Instead, it involves subjecting assumptions to robustness analysis, which can help identify options to influence stakeholders' attitudes toward transitions.}, language = {en} } @article{BehbahaniProbstMaietal.2010, author = {Behbahani, Mehdi and Probst, M. and Mai, A. and Tran, L. and Vonderstein, K. and Keschenau, P. and Linde, T. and Steinseifer, U. and Behr, M. and Mottaghy, K.}, title = {The influence of high shear on thrombosis and hemolysis in artificial organs}, series = {The International Journal of Artificial Organs}, volume = {33}, journal = {The International Journal of Artificial Organs}, number = {7}, publisher = {Sage}, address = {Thousand Oaks}, issn = {0391-3988}, pages = {426 -- 426}, year = {2010}, language = {en} } @article{BallVoegeleGrajewskietal.2021, author = {Ball, Christopher Stephen and V{\"o}gele, Stefan and Grajewski, Matthias and Kuckshinrichs, Wilhelm}, title = {E-mobility from a multi-actor point of view: Uncertainties and their impacts}, series = {Technological Forecasting and Social Change}, volume = {170}, journal = {Technological Forecasting and Social Change}, number = {Art. 120925}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {0040-1625}, doi = {10.1016/j.techfore.2021.120925}, year = {2021}, language = {en} } @article{MiyamotoKanekoMatsuoetal.2010, author = {Miyamoto, Ko-ichiro and Kaneko, Kazumi and Matsuo, Akira and Wagner, Torsten and Kanoh, Shin`ichiro and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo}, title = {Miniaturized chemical imaging sensor system using an OLED display panel}, series = {Procedia Engineering}, volume = {5}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2010.09.160}, pages = {516 -- 519}, year = {2010}, abstract = {The chemical imaging sensor is a semiconductor-based chemical sensor that can visualize the two-dimensional distribution of specific ions or molecules in the solution. In this study, we developed a miniaturized chemical imaging sensor system with an OLED display panel as a light source that scans the sensor plate. In the proposed configuration, the display panel is placed directly below the sensor plate and illuminates the back surface. The measured area defined by illumination can be arbitrarily customized to fit the size and the shape of the sample to be measured. The waveform of the generated photocurrent, the currentvoltage characteristics and the pH sensitivity were investigated and pH imaging with this miniaturized system was demonstrated.}, language = {en} } @article{PoghossianWagnerSchoening2010, author = {Poghossian, Arshak and Wagner, Holger and Sch{\"o}ning, Michael Josef}, title = {Automatisiertes „wafer level"-Testsystem zur Charakterisierung von siliziumbasierten Chemo- und Biosensoren}, series = {Tagungsband: Sensoren und Messsysteme 2010}, journal = {Tagungsband: Sensoren und Messsysteme 2010}, publisher = {VDE Verlag}, address = {Berlin}, isbn = {978-3-8007-3260-9}, pages = {89 -- 92}, year = {2010}, abstract = {Es wurde ein automatisiertes, computerunterst{\"u}tztes Testsystem f{\"u}r die Funktionspr{\"u}fung und Charakterisierung von (bio-)chemischen Sensoren auf Waferebene entwickelt und in einen konventionellen Spitzenmessplatz integriert. Das System erm{\"o}glicht die Charakterisierung und Identifizierung „funktionstauglicher" Sensoren bereits auf Waferebene zwischen den einzelnen Herstellungsschritten, wodurch weitere, bisher {\"u}bliche Verarbeitungsschritte wie das Fixieren, Bonden und Verkapseln f{\"u}r die defekten oder nicht funktionstauglichen Sensorstrukturen entf{\"a}llt. Außerdem bietet eine speziell entworfene miniaturisierte Durchflussmesszelle die M{\"o}glichkeit, bereits auf Waferlevel die Sensitivit{\"a}t, Drift, Hysterese und Ansprechzeit der (bio-)chemischen Sensoren zu charakterisieren. Das System wurde exemplarisch mit kapazitiven, pH-sensitiven EIS- (Elektrolyt-Isolator-Silizium) Strukturen und ISFET- (ionensensitiver Feldeffekttransistor) Strukturen mit verschiedenen Geometrien und Gate-Layouts getestet.}, language = {de} } @article{KirchnerOberlaenderFriedrichetal.2010, author = {Kirchner, Patrick and Oberl{\"a}nder, Jan and Friedrich, Peter and Rysstad, Gunnar and Berger, J{\"o}rg and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Realization of a calorimetric gas sensor on polyimide foil for applications in aseptic food industry}, series = {Procedia Engineering}, volume = {5}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2010.09.098}, pages = {264 -- 267}, year = {2010}, abstract = {A calorimetric gas sensor is presented for the monitoring of gas-phase H2O2 at elevated temperature during sterilization processes in aseptic food industry. The sensor consists of two temperature-sensitive thin-film resistances built up on a polyimide foil with a thickness of 25 μm, which are passivated with a layer of SU-8 photo resist and catalytically activated with manganese(IV) oxide. Instead of an active heating structure, the calorimetric sensor utilizes the elevated temperature of an evaporated H2O2 aerosol. In an experimental set-up, the sensor has shown a sensitivity of 4.78 °C/(\%v/v) in a H2O2 concentration range of 0 to 10\% v/v at an evaporation temperature of 240 ∘C. Furthermore, the sensor possesses the same, unchanged sensor signal even at varied evaporation temperatures of the gas stream. The sensor characterization demonstrates the suitability of the calorimetric gas sensor for monitoring the efficiency of sterilization processes.}, language = {en} } @article{BohrnStuetzFleischeretal.2010, author = {Bohrn, Ulrich and St{\"u}tz, Evamaria and Fleischer, Maximilian and Sch{\"o}ning, Michael Josef}, title = {Real-time detection of CO by eukaryotic cells}, series = {Procedia Engineering}, volume = {5}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, pages = {17 -- 20}, year = {2010}, abstract = {In this contribution, we focus on the detection of toxic gases with living eukaryotic cells. A cell-based gas sensor system, able to measure the effects of direct exposure of gases to cells in real-time, was set up. Impedance data as well as oxygen consumption of Chinese hamster lung fibroblast cells (V79) were analysed upon exposure to carbon monoxide (CO). The CO (diluted in wet synthetic air) affects the cell respiration as indicated by an attenuated respiration signal after the CO exposure as well as an instant increase of the capacitive part of the impedance signal during the gas exposure.}, language = {en} } @article{SponagelBaroudFalketal.2004, author = {Sponagel, Stefan and Baroud, Gamal and Falk, R. and Crookshank, M.}, title = {Experimental and theoretical investigation of directional permeability of human vertebral cancellous bone for cement infiltration. G. Baroud, R. Falk, M. Crookshank, S. Sponagel, T. Steffen}, series = {Journal of Biomechanics. 37 (2004), H. 2}, journal = {Journal of Biomechanics. 37 (2004), H. 2}, isbn = {0021-9290}, pages = {189 -- 196}, year = {2004}, language = {en} } @article{KirchnerSpelthahnSchoeningetal.2010, author = {Kirchner, Patrick and Spelthahn, Heiko and Sch{\"o}ning, Michael Josef and Henkel, Hartmut and Schneider, Andreas and Friedrich, Peter and Kolstad, Jens and Berger, J{\"o}rg}, title = {Realisierung eines Polyimid-basierten kalorimetrischen Gassensors zur Inline-{\"U}berwachung der H2O2-Konzentration in aseptischen Abf{\"u}llsystemen}, series = {Tagungsband: Sensoren und Messsysteme 2010}, journal = {Tagungsband: Sensoren und Messsysteme 2010}, publisher = {VDE Verlag}, address = {Berlin}, isbn = {978-3-8007-3260-9}, pages = {607 -- 612}, year = {2010}, abstract = {In aseptischen Abf{\"u}llsystemen wird Wasserstoffperoxid in der Gasphase aufgrund der stark oxidativen Wirkung zur Packstoffentkeimung eingesetzt. Dabei wird die Effizienz der Entkeimung im Wesentlichen von der vorliegenden H2O2-Konzentration im Packstoff bestimmt. Zur Inline-{\"U}berwachung der H2O2-Konzentration wurde ein kalorimetrischer Gassensor auf Basis einer flexiblen Polyimidfolie aus temperatursensitiven D{\"u}nnschicht-Widerst{\"a}nden und Mangan(IV)-oxid als katalytische Transducerschicht realisiert. Der Sensor weist ein lineares Ansprechverhalten mit einer Sensitivit{\"a}t von 7,15 °C/Vol.-\% in einem H2O2-Konzentrationsbereich von 0 bis 8 Vol.-\% auf. Weiterhin wurde zur Auslesung des Sensorsignals eine RFID-Elektronik, bestehend aus einem Sensor-Tag und einer Sende-/Empfangseinheit ausgelegt, sowie eine Abfolge des Messzyklus aufgestellt. Im weiteren Verlauf soll der kalorimetrische Gassensor mit der RFID-Elektronik gekoppelt und in eine Testverpackung zur Inline-{\"U}berwachung der H2O2-Konzentration in aseptischen Abf{\"u}llsystemen implementiert werden.}, language = {de} } @article{SpelthahnSchaffrathCoppeetal.2010, author = {Spelthahn, Heiko and Schaffrath, Sophie and Coppe, Thomas and Rufi, Frederic and Sch{\"o}ning, Michael Josef}, title = {Development of an electrolyte-insulator-semiconductor (EIS) based capacitive heavy metal sensor for the detection of Pb2+ und Cd2+ ions}, series = {Physica status solidi (a) : applications and material science}, volume = {207}, journal = {Physica status solidi (a) : applications and material science}, number = {4}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6300}, doi = {10.1002/pssa.200983306}, pages = {930 -- 934}, year = {2010}, abstract = {Chalcogenide glass materials as membranes for potentiometric sensors for chemical analysis in solutions have been studied since more than 20 years. In this work, an electrolyte-insulator-semiconductor structure was combined with chalcogenide glass membranes prepared by means of the pulsed laser deposition technique. Depending on the membrane composition a selectivity to different ions (Cd2+ and Pb2+) is achieved. The different sensor membranes have been physically characterised using microscopy, ellipsometry, profilometry, atomic force microscopy (AFM), scanning electron microscopy (SEM) and Rutherford backscattering spectrometry (RBS). The electrochemical behaviour has been investigated via capacitance/voltage (C/V) and constant capacitance (ConCap) measurements and results in a Cd2+ sensitivity of 23.1 ± 0.6 mV per decade in a linear range from 7 × 10-6 to 10-2 mol/l and 24.4 ± 0.5 mV per decade in a linear range from 5 × 10-6 to 10-2 mol/l for Pb2+, respectively.}, language = {en} } @article{WernerSpelthahnSchoeningetal.2010, author = {Werner, Frederik and Spelthahn, Heiko and Sch{\"o}ning, Michael Josef and Krumbe, Christoph and Wagner, Torsten and Yoshinobu, Tatsuo and Keusgen, Michael}, title = {Neue Ansteuerungselektronik f{\"u}r LAPS-basierte Biosensoren zur gleichzeitig ortsaufgel{\"o}sten Messung der pH-Konzentration}, series = {Tagungsband: Sensoren und Messsysteme 2010}, journal = {Tagungsband: Sensoren und Messsysteme 2010}, publisher = {VDE Verlag}, address = {Berlin}, isbn = {978-3-8007-3260-9}, pages = {109 -- 114}, year = {2010}, abstract = {Ein lichtadressierbarer potentiometrischer Sensor (LAPS) kann die Konzentration eines oder mehrerer Analyten ortsaufgel{\"o}st auf der Sensoroberfl{\"a}che nachweisen. Dazu wird mit einer modulierten Lichtquelle die Halbleiterstruktur des zu untersuchenden Bereiches angeregt und ein entsprechender Photostrom ausgelesen. Durch gleichzeitige Anregung mehrere Bereiche durch Lichtquellen mit unterschiedlichen Modulationsfrequenzen k{\"o}nnen diese auch zeitgleich ausgelesen werden. Mit der neuen, hier vorgestellten Ansteuerungselektronik integriert in einem "Field Programmable Gate Array" (FPGA) ist es m{\"o}glich, mehrere Leuchtquellen gleichzeitig mit unterschiedlichen, w{\"a}hrend der Laufzeit festlegbaren Frequenzen, Phasen und Lichtintensit{\"a}ten zu betreiben. Somit kann das Frequenzverhalten des Sensors untersucht und die Konzentration des Analyten {\"u}ber das Oberfl{\"a}chenpotential mit Hilfe von Strom/Spannungs-Kurven und Phase/Spannungs-Kurven bestimmt werden.}, language = {de} } @article{DigelWehlitzKayseretal.2018, author = {Digel, Ilya and Wehlitz, V. and Kayser, Peter and Figiel-Lange, A. and Bassam, Rasha and Rundstedt, F. von}, title = {Suspension depletion approach for exemption of infected Solanum jasminoides cells from pospiviroids}, series = {Plant Pathology}, volume = {67}, journal = {Plant Pathology}, number = {2}, publisher = {Wiley}, address = {Oxford}, issn = {1365-3059}, doi = {10.1111/ppa.12750}, pages = {358 -- 365}, year = {2018}, abstract = {Despite numerous studies, viroid elimination from infected plants remains a very challenging task. This study introduces for the first time a novel 'suspension depletion' approach for exemption of Solanum jasminoides plants from viroids. The proposed method implies initial establishment of suspension cultures of the infected plant cells. The suspended cells were then physically treated (mild thermotherapy, 33 °C), which presumably delayed the replication of the viroid. The viroid concentration in the treated biomass was monitored weekly using pospiviroid-specific PCR. After 10-12 weeks of continuous treatment, a sufficient decrease in viroid concentration was observed such that the infection became undetectable by PCR. The treated single cells then gave rise to microcolonies on a solid culture medium and the obtained viroid-negative clones were further promoted to regenerate into viroid-free plants. Three years of accumulated experimental data suggests feasibility, broad applicability, and good efficacy of the proposed approach.}, language = {en} } @article{BaeckerPoghossianSchoeningetal.2010, author = {B{\"a}cker, Matthias and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Schnitzler, Thomas and Biselli, Manfred and Zang, Werner and Wagner, Patrick}, title = {Entwicklung eines modularen festk{\"o}rperbasierten Sensorsystems f{\"u}r die {\"U}berwachung von Zellkulturfermentationen}, series = {Tagungsband: Sensoren und Messsysteme 2010}, journal = {Tagungsband: Sensoren und Messsysteme 2010}, publisher = {VDE Verlag}, address = {Berlin}, isbn = {978-3-8007-3260-9}, pages = {688 -- 698}, year = {2010}, abstract = {In diesem Beitrag werden Ergebnisse der Entwicklung eines modularen festk{\"o}rperbasierten Sensorsystems f{\"u}r die {\"U}berwachung von Zellkulturfermentationen pr{\"a}sentiert. Zur Messung der Elektrolytleitf{\"a}higkeit wurde das Layout von Interdigitalelektroden angepasst, um in vergleichsweise gut leitenden Elektrolyten zu messen. Durch Quervernetzung von Glucose-Oxidase mit Glutaraldehyd und Immobilisierung auf einer Platinelektrode wurde ein amperometrischer Glucosesensor mit einem linearen Messbereich von bis zu 2 mM und einer Sensitivit{\"a}t von 168 nA/mM realisiert.}, language = {de} } @article{StaatBaroudTopcuetal.2008, author = {Staat, Manfred and Baroud, Gamal and Topcu, M. and Sponagel, Stefan}, title = {Soft Materials in Technology and Biology - Characteristics, Properties, and Parameter Identification}, series = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)}, journal = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-540-75408-4}, pages = {253 -- 315}, year = {2008}, language = {en} } @article{TemizArtmannBaşkurtPekcetinetal.2000, author = {Temiz Artmann, Ayseg{\"u}l and Ba{\c{s}}kurt, Oǧuz Kerim and Pekcetin, C. and Kandemir, F.}, title = {Leukocyte activation, oxidant stress and red blood cell properties after acute, exhausting exercise in rats. Temiz, A.; Baskurt, O. K., Pekcetin, C.; Kandemir, F.; G{\"u}re, A.}, series = {Clinical Hemorheology and Microcirculation. 22 (2000), H. 4}, journal = {Clinical Hemorheology and Microcirculation. 22 (2000), H. 4}, isbn = {1386-0291}, pages = {253 -- 259}, year = {2000}, language = {en} }