@article{ThomaThomessenGardietal.2023, author = {Thoma, Andreas and Thomessen, Karolin and Gardi, Alessandro and Fisher, A. and Braun, Carsten}, title = {Prioritising paths: An improved cost function for local path planning for UAV in medical applications}, series = {The Aeronautical Journal}, journal = {The Aeronautical Journal}, number = {First View}, publisher = {Cambridge University Press}, address = {Cambridge}, issn = {0001-9240 (Print)}, doi = {10.1017/aer.2023.68}, pages = {1 -- 18}, year = {2023}, abstract = {Even the shortest flight through unknown, cluttered environments requires reliable local path planning algorithms to avoid unforeseen obstacles. The algorithm must evaluate alternative flight paths and identify the best path if an obstacle blocks its way. Commonly, weighted sums are used here. This work shows that weighted Chebyshev distances and factorial achievement scalarising functions are suitable alternatives to weighted sums if combined with the 3DVFH* local path planning algorithm. Both methods considerably reduce the failure probability of simulated flights in various environments. The standard 3DVFH* uses a weighted sum and has a failure probability of 50\% in the test environments. A factorial achievement scalarising function, which minimises the worst combination of two out of four objective functions, reaches a failure probability of 26\%; A weighted Chebyshev distance, which optimises the worst objective, has a failure probability of 30\%. These results show promise for further enhancements and to support broader applicability.}, language = {en} } @article{FalkenbergKohnBottetal.2023, author = {Falkenberg, Fabian and Kohn, Sophie and Bott, Michael and Bongaerts, Johannes and Siegert, Petra}, title = {Biochemical characterisation of a novel broad pH spectrum subtilisin from Fictibacillus arsenicus DSM 15822ᵀ}, series = {FEBS Open Bio}, volume = {13}, journal = {FEBS Open Bio}, number = {11}, publisher = {Wiley}, address = {Hoboken, NJ}, issn = {2211-5463}, doi = {10.1002/2211-5463.13701}, pages = {2035 -- 2046}, year = {2023}, abstract = {Subtilisins from microbial sources, especially from the Bacillaceae family, are of particular interest for biotechnological applications and serve the currently growing enzyme market as efficient and novel biocatalysts. Biotechnological applications include use in detergents, cosmetics, leather processing, wastewater treatment and pharmaceuticals. To identify a possible candidate for the enzyme market, here we cloned the gene of the subtilisin SPFA from Fictibacillus arsenicus DSM 15822ᵀ (obtained through a data mining-based search) and expressed it in Bacillus subtilis DB104. After production and purification, the protease showed a molecular mass of 27.57 kDa and a pI of 5.8. SPFA displayed hydrolytic activity at a temperature optimum of 80 °C and a very broad pH optimum between 8.5 and 11.5, with high activity up to pH 12.5. SPFA displayed no NaCl dependence but a high NaCl tolerance, with decreasing activity up to concentrations of 5 m NaCl. The stability enhanced with increasing NaCl concentration. Based on its substrate preference for 10 synthetic peptide 4-nitroanilide substrates with three or four amino acids and its phylogenetic classification, SPFA can be assigned to the subgroup of true subtilisins. Moreover, SPFA exhibited high tolerance to 5\% (w/v) SDS and 5\% H₂O₂ (v/v). The biochemical properties of SPFA, especially its tolerance of remarkably high pH, SDS and H₂O₂, suggest it has potential for biotechnological applications.}, language = {en} } @article{RuebbelkeVoegeleGrajewskietal.2023, author = {R{\"u}bbelke, Dirk and V{\"o}gele, Stefan and Grajewski, Matthias and Zobel, Luzy}, title = {Cross border adjustment mechanism: Initial data for the assessment of hydrogen-based steel production}, series = {Data in Brief}, volume = {47}, journal = {Data in Brief}, number = {Article 108907}, publisher = {Elsevier}, address = {Amsterdam}, issn = {2352-3409}, doi = {10.1016/j.dib.2023.108907}, pages = {1 -- 5}, year = {2023}, abstract = {Ambitious climate targets affect the competitiveness of industries in the international market. To prevent such industries from moving to other countries in the wake of increased climate protection efforts, cost adjustments may become necessary. Their design requires knowledge of country-specific production costs. Here, we present country-specific cost figures for different production routes of steel, paying particular attention to transportation costs. The data can be used in floor price models aiming to assess the competitiveness of different steel production routes in different countries (R{\"u}bbelke, 2022).}, language = {en} } @article{CheenakulaGriebelMontagetal.2023, author = {Cheenakula, Dheeraja and Griebel, Kai and Montag, David and Gr{\"o}mping, Markus}, title = {Concept development of a mainstream deammonification and comparison with conventional process in terms of energy, performance and economical construction perspectives}, series = {Frontiers in Microbiology}, volume = {14}, journal = {Frontiers in Microbiology}, number = {11155235}, editor = {Huang, Xiaowu}, publisher = {Frontiers}, issn = {1664-302X}, doi = {10.3389/fmicb.2023.1155235}, pages = {1 -- 15}, year = {2023}, abstract = {Deammonification for nitrogen removal in municipal wastewater in temperate and cold climate zones is currently limited to the side stream of municipal wastewater treatment plants (MWWTP). This study developed a conceptual model of a mainstream deammonification plant, designed for 30,000 P.E., considering possible solutions corresponding to the challenging mainstream conditions in Germany. In addition, the energy-saving potential, nitrogen elimination performance and construction-related costs of mainstream deammonification were compared to a conventional plant model, having a single-stage activated sludge process with upstream denitrification. The results revealed that an additional treatment step by combining chemical precipitation and ultra-fine screening is advantageous prior the mainstream deammonification. Hereby chemical oxygen demand (COD) can be reduced by 80\% so that the COD:N ratio can be reduced from 12 to 2.5. Laboratory experiments testing mainstream conditions of temperature (8-20°C), pH (6-9) and COD:N ratio (1-6) showed an achievable volumetric nitrogen removal rate (VNRR) of at least 50 gN/(m3∙d) for various deammonifying sludges from side stream deammonification systems in the state of North Rhine-Westphalia, Germany, where m3 denotes reactor volume. Assuming a retained Norganic content of 0.0035 kgNorg./(P.E.∙d) from the daily loads of N at carbon removal stage and a VNRR of 50 gN/(m3∙d) under mainstream conditions, a resident-specific reactor volume of 0.115 m3/(P.E.) is required for mainstream deammonification. This is in the same order of magnitude as the conventional activated sludge process, i.e., 0.173 m3/(P.E.) for an MWWTP of size class of 4. The conventional plant model yielded a total specific electricity demand of 35 kWh/(P.E.∙a) for the operation of the whole MWWTP and an energy recovery potential of 15.8 kWh/(P.E.∙a) through anaerobic digestion. In contrast, the developed mainstream deammonification model plant would require only a 21.5 kWh/(P.E.∙a) energy demand and result in 24 kWh/(P.E.∙a) energy recovery potential, enabling the mainstream deammonification model plant to be self-sufficient. The retrofitting costs for the implementation of mainstream deammonification in existing conventional MWWTPs are nearly negligible as the existing units like activated sludge reactors, aerators and monitoring technology are reusable. However, the mainstream deammonification must meet the performance requirement of VNRR of about 50 gN/(m3∙d) in this case.}, language = {en} } @masterthesis{Mok2023, type = {Bachelor Thesis}, author = {Mok, Pia Peixia}, title = {Flowcean Qi : a gentle Reminder to take a deep breath.}, publisher = {FH Aachen}, address = {Aachen}, pages = {84 Seiten}, year = {2023}, abstract = {Atmen tut jeder, automatisch. Es wird nicht auf die Ausf{\"u}hrung geachtet. Doch was, wenn nur ein wenig Feinschliff an unserer Atmung bereits Großes f{\"u}r unsere Gesundheit bewirkt? Von etlichen unterschiedlichen Studien wurde bezeugt, dass Atmung und Empfinden eins sind. Das pers{\"o}nliche Empfinden ist unser Portal zur Außenwelt. Die Art wie wir auf {\"a}ußerliche Reize reagieren, wie achtsam wir im Tun und Denken sind, spiegelt unsere Innenwelt und k{\"o}rperliches Wohlbefinden wieder. FLOWCEAN QI dient dazu, Stress- und Angstst{\"o}rungen im Alltagsleben f{\"u}r Berufst{\"a}tige mit hohem Stressfaktor zu reduzieren. Vor allem, um das Gesundheitssystem zu entlasten und die Psyche der Menschen gesund wieder aufzubauen. Sind Berufst{\"a}tige viel gelassener, steigen auch Leistung und Produktivit{\"a}t. Es ist immer wichtig, die Kernursache von Problemen zu finden und zu l{\"o}sen. So k{\"o}nnen auch vielerlei andere auf die Psyche zur{\"u}ckzuf{\"u}hrende Probleme der Gesellschaft gel{\"o}st werden. FLOWCEAN QI agiert durch modernste Technologie aktiv mit dem Nutzer. Die KI-Assistenz gestaltet das Lernen der Atemtechniken spaßiger, was wiederum den Lerneffekt verbessert. Der Beamer wird im Innenbereich platziert und der Tracker begleitet einen unterwegs und zeichnet die Datenanalyse auf. F{\"u}r mehr Datenschutz ist das Armband ein reines offline Produkt. F{\"o}rmlich sollte es dem Nutzer nah sein, naturverbunden, vertrauensw{\"u}rdig und beruhigend wirken. FLOWCEAN QI basiert gestalterisch auf eine antike japanische Philosophie namens „Kintsugi". Nach der japanischen Philosophie Kintsugi werden zerbrochene Teegl{\"a}ser wiederzusammengeklebt statt weggeworfen. Die in Teile getrennten Elemente werden glatt und geschmeidig wieder zusammengef{\"u}gt. Sie formen ein neues Ganzes, dass die Sch{\"o}nheit des Originals meist {\"u}bertrifft. Die {\"A}sthetik hinter „Kintsugi" nennt man „Wabi-Sabi". Es bedeutet, die Sch{\"o}nheit im Verg{\"a}nglichen, Alten oder Fehlerhaften zu verstehen. Die Philosophie dahinter wird metaphorisch auf das Design abgebildet und auf unsere Gesundheit {\"u}bertragen. Statt letztere zu ignorieren, schenken wir ihr unsere volle Aufmerksamkeit. Ziel der Produkte ist, uns stets an sie zu erinnern, sodass wir t{\"a}glich an unserem Wohlbefinden arbeiten k{\"o}nnen.}, language = {de} } @masterthesis{Oezmen2023, type = {Bachelor Thesis}, author = {{\"O}zmen, Emel}, title = {ALIGN : ein adaptives Regalsystem}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {119 Seiten}, year = {2023}, abstract = {„ALIGN" ist ein smartes M{\"o}belsystem, das den individuellen Lebensstil und die Werte der heutigen Gesellschaft widerspiegelt. Es bietet ausreichend Stauraum und erm{\"o}glicht es, Objekte gezielt in Szene zu setzen oder in den Hintergrund zu r{\"u}cken. Das vielseitige System passt sich an unterschiedliche Raum- und Nutzungsszenarien an. Es erm{\"o}glicht die individuelle Gestaltung des Wohnraums nach pers{\"o}nlichen Vorlieben und hilft, den Herausforderungen des modernen Lebens gerecht zu werden. „ALIGN" - eine passende L{\"o}sung f{\"u}r jedes Problem.}, language = {de} } @article{RingersBialonskiEgeetal.2023, author = {Ringers, Christa and Bialonski, Stephan and Ege, Mert and Solovev, Anton and Hansen, Jan Niklas and Jeong, Inyoung and Friedrich, Benjamin M. and Jurisch-Yaksi, Nathalie}, title = {Novel analytical tools reveal that local synchronization of cilia coincides with tissue-scale metachronal waves in zebrafish multiciliated epithelia}, series = {eLife}, volume = {12}, journal = {eLife}, publisher = {eLife Sciences Publications}, issn = {2050-084X}, doi = {10.7554/eLife.77701}, pages = {27 Seiten}, year = {2023}, abstract = {Motile cilia are hair-like cell extensions that beat periodically to generate fluid flow along various epithelial tissues within the body. In dense multiciliated carpets, cilia were shown to exhibit a remarkable coordination of their beat in the form of traveling metachronal waves, a phenomenon which supposedly enhances fluid transport. Yet, how cilia coordinate their regular beat in multiciliated epithelia to move fluids remains insufficiently understood, particularly due to lack of rigorous quantification. We combine experiments, novel analysis tools, and theory to address this knowledge gap. To investigate collective dynamics of cilia, we studied zebrafish multiciliated epithelia in the nose and the brain. We focused mainly on the zebrafish nose, due to its conserved properties with other ciliated tissues and its superior accessibility for non-invasive imaging. We revealed that cilia are synchronized only locally and that the size of local synchronization domains increases with the viscosity of the surrounding medium. Even though synchronization is local only, we observed global patterns of traveling metachronal waves across the zebrafish multiciliated epithelium. Intriguingly, these global wave direction patterns are conserved across individual fish, but different for left and right noses, unveiling a chiral asymmetry of metachronal coordination. To understand the implications of synchronization for fluid pumping, we used a computational model of a regular array of cilia. We found that local metachronal synchronization prevents steric collisions, i.e., cilia colliding with each other, and improves fluid pumping in dense cilia carpets, but hardly affects the direction of fluid flow. In conclusion, we show that local synchronization together with tissue-scale cilia alignment coincide and generate metachronal wave patterns in multiciliated epithelia, which enhance their physiological function of fluid pumping.}, language = {en} } @article{LuftBremenLuft2023, author = {Luft, Angela and Bremen, Sebastian and Luft, Nils}, title = {A cost/benefit and flexibility evaluation framework for additive technologies in strategic factory planning}, series = {Processes}, volume = {11}, journal = {Processes}, number = {7}, publisher = {MDPI}, address = {Basel}, issn = {2227-9717}, doi = {10.3390/pr11071968}, pages = {Artikel 1968}, year = {2023}, abstract = {There is a growing demand for more flexibility in manufacturing to counter the volatility and unpredictability of the markets and provide more individualization for customers. However, the design and implementation of flexibility within manufacturing systems are costly and only economically viable if applicable to actual demand fluctuations. To this end, companies are considering additive manufacturing (AM) to make production more flexible. This paper develops a conceptual model for the impact quantification of AM on volume and mix flexibility within production systems in the early stages of the factory-planning process. Together with the model, an application guideline is presented to help planners with the flexibility quantification and the factory design process. Following the development of the model and guideline, a case study is presented to indicate the potential impact additive technologies can have on manufacturing flexibility Within the case study, various scenarios with different production system configurations and production programs are analyzed, and the impact of the additive technologies on volume and mix flexibility is calculated. This work will allow factory planners to determine the potential impacts of AM on manufacturing flexibility in an early planning stage and design their production systems accordingly.}, language = {en} } @book{SeptZillingerWiechertetal.2023, author = {Sept, Marcel and Zillinger, Christina and Wiechert, Johanna and Thelen, Marius}, title = {Aachener Online-Schriften Wirtschaft und Recht. Band 6. 01/2023}, editor = {Kroll-Ludwigs, Kathrin and Bassen-Metz, Yasmine and Bernecker, Andreas and Eggert, Mathias and Fritz, Thomas and Golland, Alexander and H{\"o}hne, Tim and Tran, Duc Hung and Vogt, J{\"u}rgen}, publisher = {FH Aachen / Fachbereich Wirtschaftswissenschaften}, address = {Aachen}, publisher = {Fachhochschule Aachen}, pages = {265 Seiten}, year = {2023}, abstract = {Inhaltsverzeichnis - Bachelorarbeiten 1. Zukunft der Rente - Kann eine Erwerbst{\"a}tigenversicherung das demografische Problem nachhaltig l{\"o}sen? - Marcel Sept | Seite 4-73 2. Die versammlungsgebundenen Aktion{\"a}rsrechte in der neuen virtuellen Hauptversammlung - eine Bewertung aus Unternehmer- und Aktion{\"a}rssicht - Christina Zillinger | Seite 74-130 3. Praxisleitfaden f{\"u}r den Arbeitgeber zum gesetzlichen Sonderk{\"u}ndigungsschutz - Was muss der Arbeitgeber tun, um durch Gesetz besonders gesch{\"u}tzten Arbeitnehmern k{\"u}ndigen zu k{\"o}nnen? - Johanna Wiechert | Seite 131-195 4. Die Steuerverg{\"u}nstigung bei Umstrukturierungen im Konzern nach \S 6a GrEStG im Lichte der aktuellen Rechtsprechung - Marius Thelen | Seite 196-265}, language = {de} } @article{HoffstadtCheenakulaNikolauszetal.2023, author = {Hoffstadt, Kevin and Cheenakula, Dheeraja and Nikolausz, Marcell and Krafft, Simone and Harms, Hauke and Kuperjans, Isabel}, title = {Design and construction of a new reactor for flexible biomethanation of hydrogen}, series = {Fermentation}, volume = {9}, journal = {Fermentation}, number = {8}, publisher = {MDPI}, address = {Basel}, issn = {2311-5637}, doi = {10.3390/fermentation9080774}, pages = {1 -- 16}, year = {2023}, abstract = {The increasing share of renewable electricity in the grid drives the need for sufficient storage capacity. Especially for seasonal storage, power-to-gas can be a promising approach. Biologically produced methane from hydrogen produced from surplus electricity can be used to substitute natural gas in the existing infrastructure. Current reactor types are not or are poorly optimized for flexible methanation. Therefore, this work proposes a new reactor type with a plug flow reactor (PFR) design. Simulations in COMSOL Multiphysics ® showed promising properties for operation in laminar flow. An experiment was conducted to support the simulation results and to determine the gas fraction of the novel reactor, which was measured to be 29\%. Based on these simulations and experimental results, the reactor was constructed as a 14 m long, 50 mm diameter tube with a meandering orientation. Data processing was established, and a step experiment was performed. In addition, a kLa of 1 h-1 was determined. The results revealed that the experimental outcomes of the type of flow and gas fractions are in line with the theoretical simulation. The new design shows promising properties for flexible methanation and will be tested.}, language = {en} } @inproceedings{SchwagerAngeleSchwarzboezletal.2023, author = {Schwager, Christian and Angele, Florian and Schwarzb{\"o}zl, Peter and Teixeira Boura, Cristiano Jos{\´e} and Herrmann, Ulf}, title = {Model predictive assistance for operational decision making in molten salt receiver systems}, series = {SolarPACES: Solar Power \& Chemical Energy Systems}, booktitle = {SolarPACES: Solar Power \& Chemical Energy Systems}, number = {2815 / 1}, publisher = {AIP conference proceedings / American Institute of Physics}, address = {Melville, NY}, isbn = {978-0-7354-4623-6}, issn = {1551-7616 (online)}, doi = {10.1063/5.0151514}, pages = {8 Seiten}, year = {2023}, abstract = {Despite the challenges of pioneering molten salt towers (MST), it remains the leading technology in central receiver power plants today, thanks to cost effective storage integration and high cost reduction potential. The limited controllability in volatile solar conditions can cause significant losses, which are difficult to estimate without comprehensive modeling [1]. This paper presents a Methodology to generate predictions of the dynamic behavior of the receiver system as part of an operating assistance system (OAS). Based on this, it delivers proposals if and when to drain and refill the receiver during a cloudy period in order maximize the net yield and quantifies the amount of net electricity gained by this. After prior analysis with a detailed dynamic two-phase model of the entire receiver system, two different reduced modeling approaches where developed and implemented in the OAS. A tailored decision algorithm utilizes both models to deliver the desired predictions efficiently and with appropriate accuracy.}, language = {en} } @article{BergPostweilerSteuerDankertLeichtScholten2023, author = {Berg-Postweiler, Julia and Steuer-Dankert, Linda and Leicht-Scholten, Carmen}, title = {One size does not fit all: Applying antibias trainings in academia}, series = {The International Journal of Organizational Diversity}, volume = {24}, journal = {The International Journal of Organizational Diversity}, number = {1}, publisher = {Common Ground Research Networks}, issn = {2328-6261 (Print)}, doi = {10.18848/2328-6261/CGP/v24i01/1-23}, pages = {1 -- 23}, year = {2023}, abstract = {Antibias training is increasingly demanded and practiced in academia and industry to increase employees' sensitivity to discrimination, racism, and diversity. Under the heading of "Diversity Management," antibias trainings are mainly offered as one-off workshops intending to raise awareness of unconscious biases, create a diversity-affirming corporate culture, promote awareness of the potential of diversity, and ultimately enable the reflection of diversity in development processes. However, coming from childhood education, research and scientific articles on the sustainable effectiveness of antibias in adulthood, especially in academia, are very scarce. In order to fill this research gap, the article aims to explore how sustainable the effects of individual antibias trainings on participants' behavior are. In order to investigate this, participant observation in a qualitative pre-post setting was conducted, analyzing antibias training in an academic context. Two observers actively participated in the training sessions and documented the activities and reflection processes of the participants. Overall, the results question the effectiveness of single antibias trainings and show that a target-group adaptive approach is mandatory owing to the background of the approach in early childhood education. Therefore, antibias work needs to be adapted to the target group's needs and realities of life. Furthermore, the study reveals that single antibias trainings must be embedded in a holistic diversity management approach to stimulate sustainable reflection processes among the target group. This article is one of the first to scientifically evaluate antibias training effectiveness, especially in engineering sciences and the university context.}, language = {en} } @inproceedings{SteuerDankert2023, author = {Steuer-Dankert, Linda}, title = {Training future skills - sustainability, interculturality \& innovation in a digital design thinking format}, series = {Proceedings of the 19th International CDIO Conference}, booktitle = {Proceedings of the 19th International CDIO Conference}, pages = {12 Seiten}, year = {2023}, abstract = {The complex questions of today for a world of tomorrow are characterized by their global impact. Solutions must therefore not only be sustainable in the sense of the three pillars of sustainability (economic, environmental, and social) but must also function globally. This goes hand in hand with the need for intercultural acceptance of developed services and products. To achieve this, engineers, as the problem solvers of the future, must be able to work in intercultural teams on appropriate solutions, and be sensitive to intercultural perspectives. To equip the engineers of the future with the so-called future skills, teaching concepts are needed in which students can acquire these methods and competencies in application-oriented formats. The presented course "Applying Design Thinking - Sustainability, Innovation and Interculturality" was developed to teach future skills from the competency areas Digital Key Competencies, Classical Competencies and Transformative Competencies. The CDIO Standard 3.0, in particular the standards 5, 6, 7 and 8, was used as a guideline. The course aims to prepare engineering students from different disciplines and cultures for their future work in an international environment by combining a digital teaching format with an interdisciplinary, transdisciplinary and intercultural setting for solving sustainability challenges. The innovative moment lies in the digital application of design thinking and the inclusion of intercultural as well as trans- and interdisciplinary perspectives in innovation development processes. In this paper, the concept of the course will be presented in detail and the particularities of a digital implementation of design thinking will be addressed. Subsequently, the potentials and challenges will be reflected and practical advice for integrating design thinking in engineering education will be given.}, language = {en} } @misc{HilleStumpfMayntzetal.2023, author = {Hille, Sebastian and Stumpf, Eike and Mayntz, Joscha and Dahmann, Peter}, title = {Prediction of sound exposure caused by a landing motor glider with recuperating propellers}, series = {AIAA SCITECH 2023 Forum}, journal = {AIAA SCITECH 2023 Forum}, publisher = {AIAA}, address = {Reston, Va.}, doi = {10.2514/6.2023-0211}, year = {2023}, abstract = {This paper presents an approach to predicting the sound exposure on the ground caused by a landing aircraft with recuperating propellers. The noise source along the trajectory of a flight specified for a steeper approach is simulated based on measurements of sound power levels and additional parameters of a single propeller placed in a wind tunnel. To validate the measured data/measurement results, these simulations are also supported by overflight measurements of a test aircraft. It is shown that the simple source models of propellers do not provide fully satisfactory results since the sound levels are estimated too low. Nevertheless, with a further reference comparison, margins for an acceptable increase in the sound power level of the aircraft on its now steeper approach path could be estimated. Thus, in this case, a +7 dB increase in SWL would not increase the SEL compared to the conventional approach within only 2 km ahead of the airfield.}, language = {en} } @inproceedings{LahrsKrisamHerrmann2023, author = {Lahrs, Lennart and Krisam, Pierre and Herrmann, Ulf}, title = {Envisioning a collaborative energy system planning platform for the energy transition at the district level}, series = {ECOS 2023. The 36th International Conference on Efficiency, Cost, Optimization, Simulation and Environmental Impact of Energy Systems}, booktitle = {ECOS 2023. The 36th International Conference on Efficiency, Cost, Optimization, Simulation and Environmental Impact of Energy Systems}, publisher = {Procedings of ECOS 2023}, doi = {10.52202/069564-0284}, pages = {3163 -- 3170}, year = {2023}, abstract = {Residential and commercial buildings account for more than one-third of global energy-related greenhouse gas emissions. Integrated multi-energy systems at the district level are a promising way to reduce greenhouse gas emissions by exploiting economies of scale and synergies between energy sources. Planning district energy systems comes with many challenges in an ever-changing environment. Computational modelling established itself as the state-of-the-art method for district energy system planning. Unfortunately, it is still cumbersome to combine standalone models to generate insights that surpass their original purpose. Ideally, planning processes could be solved by using modular tools that easily incorporate the variety of competing and complementing computational models. Our contribution is a vision for a collaborative development and application platform for multi-energy system planning tools at the district level. We present challenges of district energy system planning identified in the literature and evaluate whether this platform can help to overcome these challenges. Further, we propose a toolkit that represents the core technical elements of the platform. Lastly, we discuss community management and its relevance for the success of projects with collaboration and knowledge sharing at their core.}, language = {en} } @incollection{StollenwerkFranzkeMaureretal.2023, author = {Stollenwerk, Dominik and Franzke, Till and Maurer, Florian and Reinkensmeier, Sebastian and Kim, Franken and Tambornino, Philipp and Haas, Florian and Rieke, Christian and Hermanuz, Andreas and Borchert, J{\"o}rg and Ritz, Thomas and Sander, Volker}, title = {Smarte Lades{\"a}ulen : Netz- und Marktdienliches {\"o}ffentliches Laden}, series = {Towards the New Normal in Mobility : Technische und betriebswirtschaftliche Aspekte}, booktitle = {Towards the New Normal in Mobility : Technische und betriebswirtschaftliche Aspekte}, editor = {Proff, Heike}, publisher = {Springer Gabler}, address = {Wiesbaden}, isbn = {978-3-658-39437-0 (Print)}, doi = {10.1007/978-3-658-39438-7_18}, pages = {287 -- 304}, year = {2023}, abstract = {Stand 01.01.2022 sind in Deutschland 618.460 elektrisch angetriebene KFZ zugelassen. Insgesamt sind derzeit 48.540.878 KFZ zugelassen, was einer Elektromobilit{\"a}tsquote von ca. 1,2 \% entspricht. Derzeit werden Elektromobile {\"u}ber Ladestationen oder Steckdosen mit dem Stromnetz verbunden und {\"u}blicherweise mit der vollen Ladekapazit{\"a}t des Anschlusses aufgeladen, bis das Batteriemanagementsystem des Fahrzeugs abh{\"a}ngig vom Ladezustand der Batterie die Ladeleistung reduziert.}, language = {de} } @article{HaegerGrankinWagner2023, author = {Haeger, Gerrit and Grankin, Alina and Wagner, Michaela}, title = {Construction of an Aspergillus oryzae triple amylase deletion mutant as a chassis to evaluate industrially relevant amylases using multiplex CRISPR/Cas9 editing technology}, series = {Applied Research}, journal = {Applied Research}, number = {Early View}, publisher = {Wiley-VCH}, issn = {2702-4288}, doi = {10.1002/appl.202200106}, pages = {1 -- 15}, year = {2023}, abstract = {Aspergillus oryzae is an industrially relevant organism for the secretory production of heterologous enzymes, especially amylases. The activities of potential heterologous amylases, however, cannot be quantified directly from the supernatant due to the high background activity of native α-amylase. This activity is caused by the gene products of amyA, amyB, and amyC. In this study, an in vitro CRISPR/Cas9 system was established in A. oryzae to delete these genes simultaneously. First, pyrG of A. oryzae NSAR1 was mutated by exploiting NHEJ to generate a counter-selection marker. Next, all amylase genes were deleted simultaneously by co-transforming a repair template carrying pyrG of Aspergillus nidulans and flanking sequences of amylase gene loci. The rate of obtained triple knock-outs was 47\%. We showed that triple knockouts do not retain any amylase activity in the supernatant. The established in vitro CRISPR/Cas9 system was used to achieve sequence-specific knock-in of target genes. The system was intended to incorporate a single copy of the gene of interest into the desired host for the development of screening methods. Therefore, an integration cassette for the heterologous Fpi amylase was designed to specifically target the amyB locus. The site-specific integration rate of the plasmid was 78\%, with exceptional additional integrations. Integration frequency was assessed via qPCR and directly correlated with heterologous amylase activity. Hence, we could compare the efficiency between two different signal peptides. In summary, we present a strategy to exploit CRISPR/Cas9 for gene mutation, multiplex knock-out, and the targeted knock-in of an expression cassette in A. oryzae. Our system provides straightforward strain engineering and paves the way for development of fungal screening systems.}, language = {en} } @misc{OPUS4-10805, title = {Pr{\"u}fungsordnung f{\"u}r die Bachelorstudieng{\"a}nge „Biotechnologie" und „Biotechnologie mit Praxis- oder Auslandssemester" im Fachbereich Chemie und Biotechnologie an der FH Aachen}, address = {Aachen}, organization = {FH Aachen}, pages = {12 Seiten}, year = {2023}, abstract = {\S 1 | Geltungsbereich der Pr{\"u}fungsordnung \S 2 | Ziel des Studiums, Zweck der Pr{\"u}fung, Abschlussgrad \S 3 | Beginn, Dauer, Umfang und Gliederung des Studiums \S 4 | Zugang zum Studium, Praktikum \S 5 | Pr{\"u}fungsausschuss \S 6 | Studien- und Pr{\"u}fungselemente \S 7 | Zulassung zu den Pr{\"u}fungen \S 8 | Durchf{\"u}hrung von Pr{\"u}fungen \S 9 | Verbesserungsversuch \S 10 | Anrechnung von Studienzeiten, Studien- und Pr{\"u}fungsleistungen \S 11 | Praxissemester \S 12 | Mobilit{\"a}tssemester (Auslandssemester) \S 13 | Bachelorprojekt\S 14 | Gesamtnote, Zeugnis, Bachelorurkunde \S 15 | Inkrafttreten, Ver{\"o}ffentlichung Anlage 1 | Studienplan Kernstudium Anlage 2 | Allgemeine Kompetenzen}, language = {de} } @article{Pfaff2023, author = {Pfaff, Raphael}, title = {Braking distance prediction for vehicle consist in low-speed on-sight operation: a Monte Carlo approach}, series = {Railway Engineering Science}, volume = {31}, journal = {Railway Engineering Science}, number = {2}, publisher = {SpringerOpen}, issn = {2662-4753 (eISSN)}, doi = {10.1007/s40534-023-00303-7}, pages = {135 -- 144}, year = {2023}, abstract = {The first and last mile of a railway journey, in both freight and transit applications, constitutes a high effort and is either non-productive (e.g. in the case of depot operations) or highly inefficient (e.g. in industrial railways). These parts are typically managed on-sight, i.e. with no signalling and train protection systems ensuring the freedom of movement. This is possible due to the rather short braking distances of individual vehicles and shunting consists. The present article analyses the braking behaviour of such shunting units. For this purpose, a dedicated model is developed. It is calibrated on published results of brake tests and validated against a high-definition model for low-speed applications. Based on this model, multiple simulations are executed to obtain a Monte Carlo simulation of the resulting braking distances. Based on the distribution properties and established safety levels, the risk of exceeding certain braking distances is evaluated and maximum braking distances are derived. Together with certain parameters of the system, these can serve in the design and safety assessment of driver assistance systems and automation of these processes.}, language = {en} } @inproceedings{NierlePieper2023, author = {Nierle, Elisabeth and Pieper, Martin}, title = {Measuring social impacts in engineering education to improve sustainability skills}, series = {European Society for Engineering Education (SEFI)}, booktitle = {European Society for Engineering Education (SEFI)}, doi = {10.21427/QPR4-0T22}, pages = {9 Seiten}, year = {2023}, abstract = {In times of social climate protection movements, such as Fridays for Future, the priorities of society, industry and higher education are currently changing. The consideration of sustainability challenges is increasing. In the context of sustainable development, social skills are crucial to achieving the United Nations Sustainable Development Goals (SDGs). In particular, the impact that educational activities have on people, communities and society is therefore coming to the fore. Research has shown that people with high levels of social competence are better able to manage stressful situations, maintain positive relationships and communicate effectively. They are also associated with better academic performance and career success. However, especially in engineering programs, the social pillar is underrepresented compared to the environmental and economic pillars. In response to these changes, higher education institutions should be more aware of their social impact - from individual forms of teaching to entire modules and degree programs. To specifically determine the potential for improvement and derive resulting change for further development, we present an initial framework for social impact measurement by transferring already established approaches from the business sector to the education sector. To demonstrate the applicability, we measure the key competencies taught in undergraduate engineering programs in Germany. The aim is to prepare the students for success in the modern world of work and their future contribution to sustainable development. Additionally, the university can include the results in its sustainability report. Our method can be applied to different teaching methods and enables their comparison.}, language = {en} }