@article{BhattaraiHorbachStaatetal.2022, author = {Bhattarai, Aroj and Horbach, Andreas and Staat, Manfred and Kowalczyk, Wojciech and Tran, Thanh Ngoc}, title = {Virgin passive colon biomechanics and a literature review of active contraction constitutive models}, series = {Biomechanics}, volume = {2}, journal = {Biomechanics}, number = {2}, publisher = {MDPI}, address = {Basel}, issn = {2673-7078}, doi = {10.3390/biomechanics2020013}, pages = {138 -- 157}, year = {2022}, abstract = {The objective of this paper is to present our findings on the biomechanical aspects of the virgin passive anisotropic hyperelasticity of the porcine colon based on equibiaxial tensile experiments. Firstly, the characterization of the intestine tissues is discussed for a nearly incompressible hyperelastic fiber-reinforced Holzapfel-Gasser-Ogden constitutive model in virgin passive loading conditions. The stability of the evaluated material parameters is checked for the polyconvexity of the adopted strain energy function using positive eigenvalue constraints of the Hessian matrix with MATLAB. The constitutive material description of the intestine with two collagen fibers in the submucosal and muscular layer each has been implemented in the FORTRAN platform of the commercial finite element software LS-DYNA, and two equibiaxial tensile simulations are presented to validate the results with the optical strain images obtained from the experiments. Furthermore, this paper also reviews the existing models of the active smooth muscle cells, but these models have not been computationally studied here. The review part shows that the constitutive models originally developed for the active contraction of skeletal muscle based on Hill's three-element model, Murphy's four-state cross-bridge chemical kinetic model and Huxley's sliding-filament hypothesis, which are mainly used for arteries, are appropriate for numerical contraction numerical analysis of the large intestine.}, language = {en} } @article{UllrichGrottkeRossaintetal.2010, author = {Ullrich, Sebastian and Grottke, Oliver and Rossaint, Rolf and Staat, Manfred and Deserno, Thomas M. and Kuhlen, Torsten}, title = {Virtual Needle Simulation with Haptics for Regional Anaesthesia}, pages = {1 -- 3}, year = {2010}, language = {en} } @book{DigelZhubanovaAkimbekov2012, author = {Digel, Ilya and Zhubanova, Azhar Ahmetovna and Akimbekov, Nuraly S.}, title = {Visual Virology}, address = {Almaty}, isbn = {978-601-247-298-1}, pages = {144 S. : zahlr. Ill.}, year = {2012}, language = {en} } @article{MiyamotoBingWagneretal.2015, author = {Miyamoto, Ko-ichiro and Bing, Yu and Wagner, Torsten and Yoshinobu, Tatsuo and Sch{\"o}ning, Michael Josef}, title = {Visualization of Defects on a Cultured Cell Layer by Utilizing Chemical Imaging Sensor}, series = {Procedia Engineering}, volume = {120}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2015.08.806}, pages = {936 -- 939}, year = {2015}, abstract = {The chemical imaging sensor is a field-effect sensor which is able to visualize both the distribution of ions (in LAPS mode) and the distribution of impedance (in SPIM mode) inthe sample. In this study, a novel wound-healing assay is proposed, in which the chemical imaging sensor operated in SPIM mode is applied to monitor the defect of a cell layer brought into proximity of the sensing surface.A reduced impedance inside the defect, which was artificially formed ina cell layer, was successfully visualized in a photocurrent image.}, language = {en} } @article{MiyamotoHirayamaWagneretal.2013, author = {Miyamoto, Ko-ichiro and Hirayama, Yuji and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo}, title = {Visualization of enzymatic reaction in a microfluidic channel using chemical imaging sensor}, series = {Electrochimica acta}, journal = {Electrochimica acta}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-3859 (E-Journal); 0013-4686 (Print)}, pages = {Publ. online}, year = {2013}, language = {en} } @incollection{AkimbekovDigelSherelkhanetal.2022, author = {Akimbekov, Nuraly S. and Digel, Ilya and Sherelkhan, Dinara K. and Razzaque, Mohammed S.}, title = {Vitamin D and Phosphate Interactions in Health and Disease}, series = {Phosphate Metabolism}, booktitle = {Phosphate Metabolism}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-91621-3}, doi = {10.1007/978-3-030-91623-7_5}, pages = {37 -- 46}, year = {2022}, abstract = {Vitamin D plays an essential role in calcium and inorganic phosphate (Pi) homeostasis, maintaining their optimal levels to assure adequate bone mineralization. Vitamin D, as calcitriol (1,25(OH)2D), not only increases intestinal calcium and phosphate absorption but also facilitates their renal reabsorption, leading to elevated serum calcium and phosphate levels. The interaction of 1,25(OH)2D with its receptor (VDR) increases the efficiency of intestinal absorption of calcium to 30-40\% and phosphate to nearly 80\%. Serum phosphate levels can also influence 1,25 (OH)2D and fibroblast growth factor 23 (FGF23) levels, i.e., higher phosphate concentrations suppress vitamin D activation and stimulate parathyroid hormone (PTH) release, while a high FGF23 serum level leads to reduced vitamin D synthesis. In the vitamin D-deficient state, the intestinal calcium absorption decreases and the secretion of PTH increases, which in turn causes the stimulation of 1,25(OH)2D production, resulting in excessive urinary phosphate loss. Maintenance of phosphate homeostasis is essential as hyperphosphatemia is a risk factor of cardiovascular calcification, chronic kidney diseases (CKD), and premature aging, while hypophosphatemia is usually associated with rickets and osteomalacia. This chapter elaborates on the possible interactions between vitamin D and phosphate in health and disease.}, language = {en} } @article{AkimbekovDigelSherelkhanetal.2020, author = {Akimbekov, Nuraly S. and Digel, Ilya and Sherelkhan, Dinara K. and Lutfor, Afzalunnessa B. and Razzaque, Mohammed S.}, title = {Vitamin D and the Host-Gut Microbiome: A Brief Overview}, series = {Acta Histochemica et Cytochemica}, volume = {53}, journal = {Acta Histochemica et Cytochemica}, number = {3}, publisher = {Japan Society of Histochemistry and Cytochemistry}, address = {Osaka}, issn = {1347-5800}, doi = {10.1267/ahc.20011}, pages = {33 -- 42}, year = {2020}, abstract = {There is a growing body of evidence for the effects of vitamin D on intestinal host-microbiome interactions related to gut dysbiosis and bowel inflammation. This brief review highlights the potential links between vitamin D and gut health, emphasizing the role of vitamin D in microbiological and immunological mechanisms of inflammatory bowel diseases. A comprehensive literature search was carried out in PubMed and Google Scholar using combinations of keywords "vitamin D," "intestines," "gut microflora," "bowel inflammation". Only articles published in English and related to the study topic are included in the review. We discuss how vitamin D (a) modulates intestinal microbiome function, (b) controls antimicrobial peptide expression, and (c) has a protective effect on epithelial barriers in the gut mucosa. Vitamin D and its nuclear receptor (VDR) regulate intestinal barrier integrity, and control innate and adaptive immunity in the gut. Metabolites from the gut microbiota may also regulate expression of VDR, while vitamin D may influence the gut microbiota and exert anti-inflammatory and immune-modulating effects. The underlying mechanism of vitamin D in the pathogenesis of bowel diseases is not fully understood, but maintaining an optimal vitamin D status appears to be beneficial for gut health. Future studies will shed light on the molecular mechanisms through which vitamin D and VDR interactions affect intestinal mucosal immunity, pathogen invasion, symbiont colonization, and antimicrobial peptide expression.}, language = {en} } @article{EmonsBaadeSchoening2000, author = {Emons, H. and Baade, A. and Sch{\"o}ning, Michael Josef}, title = {Voltammetric determination of heavy metals in microvolumes of rain water}, series = {Electroanalysis. 12 (2000), H. 15}, journal = {Electroanalysis. 12 (2000), H. 15}, isbn = {1040-0397}, pages = {1171 -- 1176}, year = {2000}, language = {en} } @article{EmonsGlueckHuellenkremeretal.2001, author = {Emons, H. and Gl{\"u}ck, O. and H{\"u}llenkremer, B. and Sch{\"o}ning, Michael Josef}, title = {Voltohmmetry as an alternative detection method at polycrystalline metal film electrodes}, series = {Electroanalysis. 13 (2001), H. 8-9}, journal = {Electroanalysis. 13 (2001), H. 8-9}, isbn = {1040-0397}, pages = {677 -- 680}, year = {2001}, language = {en} } @article{SchoeningHuellenkremerGluecketal.2001, author = {Sch{\"o}ning, Michael Josef and H{\"u}llenkremer, B. and Gl{\"u}ck, O. and L{\"u}th, H. and Emons, H.}, title = {Voltohmmetry - a novel sensing principle for heavy metal determination in aqueous solutions}, series = {Sensors and Actuators B. 78 (2001), H. 1-3}, journal = {Sensors and Actuators B. 78 (2001), H. 1-3}, isbn = {0925-4005}, pages = {275 -- 280}, year = {2001}, language = {en} } @article{EmonsGlueckSchoening2001, author = {Emons, H. and Gl{\"u}ck, O. and Sch{\"o}ning, Michael Josef}, title = {Voltohmmetry - An alternative detection principle at ultrathin metal electrodes in solution}, series = {Chemical and biological sensors and analytical methods : proceedings of the international symposium / Sensor, Physical Electrochemistry, and Organic and Biological Electrochemistry Divisions. Ed.: M. Butler}, journal = {Chemical and biological sensors and analytical methods : proceedings of the international symposium / Sensor, Physical Electrochemistry, and Organic and Biological Electrochemistry Divisions. Ed.: M. Butler}, publisher = {Electrochemical Society}, address = {Pennington, NJ}, isbn = {1-56677-351-2}, pages = {1 -- 3}, year = {2001}, language = {en} } @article{StaatBallmann1988, author = {Staat, Manfred and Ballmann, J.}, title = {Wave Propagation and Focussing in Plates}, series = {Impact loading and dynamic behaviour of materials : Papers presented at the International Conference on Impact Loading and Dynamic Behaviour of Materials, Vol. 2 / Chiem, C. Y.; Kunze, L. (u.a.) [eds]}, journal = {Impact loading and dynamic behaviour of materials : Papers presented at the International Conference on Impact Loading and Dynamic Behaviour of Materials, Vol. 2 / Chiem, C. Y.; Kunze, L. (u.a.) [eds]}, publisher = {DGM Informationsges.}, address = {Oberursel}, year = {1988}, language = {en} } @article{MuellerVeggianHaenniBeuscheretal.1979, author = {M{\"u}ller-Veggian, Mattea and Haenni, D. R. and Beuscher, H. and Lieder, R. M.}, title = {Weak coupling and high-spin states in ¹⁴⁵ Eu}, series = {Nuclear physics / A. 331 (1979), H. 1}, journal = {Nuclear physics / A. 331 (1979), H. 1}, isbn = {0375-9474}, pages = {141 -- 154}, year = {1979}, language = {en} } @inproceedings{MuellerVeggianHaenniBeuscheretal.1980, author = {M{\"u}ller-Veggian, Mattea and Haenni, D. R. and Beuscher, H. and Lieder, R. M.}, title = {Weak coupling of a neutron hole to a ¹⁴⁶ Gd core ; an in-beam study of ¹⁴⁵ Gd}, series = {Structure of medium-heavy nuclei, 1979 : proceedings of the 6. European Physical Soc. Nuclear Divisional Conference on the Structure of Medium-Heavy Nuclei held in Rhodes, Greece, 1-4 May 1979 / ed. Committee: G. S. Anagnostatos ... - (Conference series / Institute of Physics London, Bristol ; 49)}, booktitle = {Structure of medium-heavy nuclei, 1979 : proceedings of the 6. European Physical Soc. Nuclear Divisional Conference on the Structure of Medium-Heavy Nuclei held in Rhodes, Greece, 1-4 May 1979 / ed. Committee: G. S. Anagnostatos ... - (Conference series / Institute of Physics London, Bristol ; 49)}, publisher = {Inst. of Physics}, address = {Bristol}, isbn = {0-85498-140-3}, pages = {133}, year = {1980}, language = {en} } @article{Dikta2001, author = {Dikta, Gerhard}, title = {Weak Representation of the Cumulative Hazard Function under Semiparametric Random Censorship Models}, series = {Statistics. 35 (2001), H. 4}, journal = {Statistics. 35 (2001), H. 4}, isbn = {0233-1888}, pages = {395 -- 410}, year = {2001}, language = {en} } @article{Pawelke1980, author = {Pawelke, Siegfried}, title = {Weak smoothness conditions for the uniform convergence of Fourier-Jacobi series}, series = {Functiones et Approximatio. Commentarii Mathematici. 9 (1980)}, journal = {Functiones et Approximatio. Commentarii Mathematici. 9 (1980)}, isbn = {0208-6573}, pages = {9 -- 13}, year = {1980}, language = {en} } @article{MalzahnWindmillerValdesRamirezetal.2011, author = {Malzahn, Kerstin and Windmiller, Joshua Ray and Vald{\´e}s-Ram{\´i}rez, Gabriela and Wang, Joseph and Sch{\"o}ning, Michael Josef}, title = {Wearable electrochemical sensors for in situ analysis in marine environments}, series = {Analyst. 136 (2011), H. 14}, journal = {Analyst. 136 (2011), H. 14}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, isbn = {0003-2654}, pages = {2912 -- 2917}, year = {2011}, language = {en} } @article{SchmidtLangenHerzogetal.1997, author = {Schmidt, Daniela and Langen, Karl-J. and Herzog, Hans and Wirths, Jochen and Holschbach, Markus and Kiwit, J{\"u}rgen C. W. and Ziemons, Karl and Coenen, Heinz-H. and M{\"u}ller-G{\"a}rtner, Hans-W.}, title = {Whole-body kinetics and dosimetry of L-3[123I]-iodo-α-methyltyrosine}, series = {European Journal of Nuclear Medicine}, volume = {24}, journal = {European Journal of Nuclear Medicine}, number = {9}, isbn = {1619-7089}, pages = {1162 -- 1166}, year = {1997}, language = {en} } @article{TemizArtmannKayser2008, author = {Temiz Artmann, Ayseg{\"u}l and Kayser, Peter}, title = {Why is Sepsis an Ongoing Clinical Challenge? Lipopolysaccharide Effects on Red Blood Cell Volume / Temiz, Ayseg{\"u}l ; Kayser, Peter}, series = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)}, journal = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-540-75408-4}, pages = {497 -- 508}, year = {2008}, language = {en} } @article{Laack2013, author = {Laack, Walter van}, title = {Why natural constants are as they are}, series = {British journal of arts and social sciences}, volume = {Vol. 15}, journal = {British journal of arts and social sciences}, number = {Nr. 2}, publisher = {BritishJournal Publ. Inc}, address = {London}, issn = {2046-9578 (E-Journal)}, pages = {198 -- 203}, year = {2013}, language = {en} }