@article{PoghossianWeilCherstvyetal.2013, author = {Poghossian, Arshak and Weil, M. and Cherstvy, A. G. and Sch{\"o}ning, Michael Josef}, title = {Electrical monitoring of polyelectrolyte multilayer formation by means of capacitive field-effect devices}, series = {Analytical and bioanalytical chemistry}, volume = {405}, journal = {Analytical and bioanalytical chemistry}, number = {20}, publisher = {Springer}, address = {Berlin}, issn = {1432-1130 ; 1618-2642}, doi = {10.1007/s00216-013-6951-9}, pages = {6425 -- 6436}, year = {2013}, abstract = {The semiconductor field-effect platform represents a powerful tool for detecting the adsorption and binding of charged macromolecules with direct electrical readout. In this work, a capacitive electrolyte-insulator-semiconductor (EIS) field-effect sensor consisting of an Al-p-Si-SiO2 structure has been applied for real-time in situ electrical monitoring of the layer-by-layer formation of polyelectrolyte (PE) multilayers (PEM). The PEMs were deposited directly onto the SiO2 surface without any precursor layer or drying procedures. Anionic poly(sodium 4-styrene sulfonate) and cationic weak polyelectrolyte poly(allylamine hydrochloride) have been chosen as a model system. The effect of the ionic strength of the solution, polyelectrolyte concentration, number and polarity of the PE layers on the characteristics of the PEM-modified EIS sensors have been studied by means of capacitance-voltage and constant-capacitance methods. In addition, the thickness, surface morphology, roughness and wettabilityof the PE mono- and multilayers have been characterised by ellipsometry, atomic force microscopy and water contact-angle methods, respectively. To explain potential oscillations on the gate surface and signal behaviour of the capacitive field-effect EIS sensor modified with a PEM, a simplified electrostatic model that takes into account the reduced electrostatic screening of PE charges by mobile ions within the PEM has been proposed and discussed.}, language = {en} } @article{SchusserLeinhosBaeckeretal.2013, author = {Schusser, Sebastian and Leinhos, Marcel and B{\"a}cker, Matthias and Poghossian, Arshak and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Impedance spectroscopy: A tool for real-time in situ monitoring of the degradation of biopolymers}, series = {Physica Status Solidi (A)}, volume = {210}, journal = {Physica Status Solidi (A)}, number = {5}, publisher = {Wiley}, address = {Weinheim}, issn = {1521-396X ; 0031-8965}, doi = {10.1002/pssa.201200941}, pages = {905 -- 910}, year = {2013}, abstract = {Investigation of the degradation kinetics of biodegradable polymers is essential for the development of implantable biomedical devices with predicted biodegradability. In this work, an impedimetric sensor has been applied for real-time and in situ monitoring of degradation processes of biopolymers. The sensor consists of two platinum thin-film electrodes covered by a polymer film to be studied. The benchmark biomedical polymer poly(D,L-lactic acid) (PDLLA) was used as a model system. PDLLA films were deposited on the sensor structure from a polymer solution by using the spin-coating method. The degradation kinetics of PDLLA films have been studied in alkaline solutions of pH 9 and 12 by means of an impedance spectroscopy (IS) method. Any changes in a polymer capacitance/resistance induced by water uptake and/or polymer degradation will modulate the global impedance of the polymer-covered sensor that can be used as an indicator of the polymer degradation. The degradation rate can be evaluated from the time-dependent impedance spectra. As expected, a faster degradation has been observed for PDLLA films exposed to pH 12 solution.}, language = {en} } @article{HuckSchiffelsHerreraetal.2013, author = {Huck, Christina and Schiffels, Johannes and Herrera, Cony N. and Schelden, Maximilian and Selmer, Thorsten and Poghossian, Arshak and Baumann, Marcus and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Metabolic responses of Escherichia coli upon glucose pulses captured by a capacitive field-effect sensor}, series = {Physica Status Solidi (A)}, volume = {210}, journal = {Physica Status Solidi (A)}, number = {5}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0031-8965}, doi = {10.1002/pssa.201200900}, pages = {926 -- 931}, year = {2013}, abstract = {Living cells are complex biological systems transforming metabolites taken up from the surrounding medium. Monitoring the responses of such cells to certain substrate concentrations is a challenging task and offers possibilities to gain insight into the vitality of a community influenced by the growth environment. Cell-based sensors represent a promising platform for monitoring the metabolic activity and thus, the "welfare" of relevant organisms. In the present study, metabolic responses of the model bacterium Escherichia coli in suspension, layered onto a capacitive field-effect structure, were examined to pulses of glucose in the concentration range between 0.05 and 2 mM. It was found that acidification of the surrounding medium takes place immediately after glucose addition and follows Michaelis-Menten kinetic behavior as a function of the glucose concentration. In future, the presented setup can, therefore, be used to study substrate specificities on the enzymatic level and may as well be used to perform investigations of more complex metabolic responses. Conclusions and perspectives highlighting this system are discussed.}, language = {en} } @article{MuribGrinsvenGrietenetal.2013, author = {Murib, M. S. and Grinsven, B. van and Grieten, L. and Janssens, S. D. and Vermeeren, V. and Eersels, K. and Broeders, J. and Ameloot, M. and Michiels, L. and Ceuninck, W. De and Haenen, K. and Sch{\"o}ning, Michael Josef and Wagner, Patrick}, title = {Electronic monitoring of chemical DNA denaturation on nanocrystalline diamond electrodes with different molarities and flow rates}, series = {Physica Status Solidi (A). Vol. 210 (2013), iss. 5}, journal = {Physica Status Solidi (A). Vol. 210 (2013), iss. 5}, publisher = {Wiley-VCH}, address = {Berlin}, issn = {0031-8965}, pages = {911 -- 917}, year = {2013}, language = {en} } @article{SchusserMenzelBaeckeretal.2013, author = {Schusser, Sebastian and Menzel, S. and B{\"a}cker, Matthias and Leinhos, Marcel and Poghossian, Arshak and Wagner, P. and Sch{\"o}ning, Michael Josef}, title = {Degradation of thin poly(lactic acid) films: characterization by capacitance-voltage, atomic force microscopy, scanning electron microscopy and contact-angle measurements}, series = {Electrochimica Acta}, volume = {Vol. 113}, journal = {Electrochimica Acta}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-3859 (E-Journal); 0013-4686 (Print)}, pages = {779 -- 784}, year = {2013}, language = {en} } @article{LindenFischoederLaacketal.2013, author = {Linden, A. and Fisch{\"o}der, M. and Laack, Walter van and Staat, Manfred}, title = {Einschr{\"a}nkung von Taluskippung und -vorschub durch Sprunggelenkorthesen nach fibularer Bandruptur}, series = {OUP Zeitschrift f{\"u}r die orthop{\"a}dische und unfallchirurgische Praxis}, volume = {2}, journal = {OUP Zeitschrift f{\"u}r die orthop{\"a}dische und unfallchirurgische Praxis}, number = {6}, publisher = {Deutscher {\"A}rzte-Verl.}, address = {K{\"o}ln}, isbn = {2193-5785}, doi = {10.3238/oup.2013.0306-0309}, pages = {306 -- 309}, year = {2013}, abstract = {Die fibulare Bandruptur z{\"a}hlt zu einer der am h{\"a}ufigsten auftretenden Verletzungen des Bewegungsapparats. In den meisten F{\"a}llen wird heute die konservativ fr{\"u}hfunktionelle Therapie mit Sprunggelenkorthesen allgemein bevorzugt. Im Rahmen der vorliegenden Studie wurden 14 verschiedene Sprunggelenkorthesen im Hinblick auf ihre Einschr{\"a}nkung von Taluskippung und Talusvorschub untersucht. Zur Simulation einer fibularen Bandruptur wurde ein Unterschenkelmodell aus Holz mit Fußteil, mit angelegten Orthesen in einen Scheuba-Halteapparat eingespannt und mit 150 N seitlich sowie anterior-posterior belastet. Anhand der erstellten "gehaltenen" R{\"o}ntgenaufnahmen konnten Taluskippung und Talusvorschub jeder einzelnen Orthese eindeutig bestimmt werden. Die meisten Orthesen erreichten zufriedenstellende Ergebnisse. Es stellte sich heraus, dass vor allem eine eng anliegende, im Gelenkbereich anatomisch angepasste Form vorteilhaft zu sein scheint.}, language = {de} } @article{ItabashiKosakaMiyamotoetal.2013, author = {Itabashi, Akinori and Kosaka, Naoki and Miyamoto, Ko-ichiro and Wagner, Torsten and Sch{\"o}ning, Michael Josef}, title = {High-speed chemical imaging system based on front-side-illuminated LAPS}, series = {Sensors and actuators B: Chemical}, volume = {182}, journal = {Sensors and actuators B: Chemical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-3077}, doi = {10.1016/j.snb.2013.03.016}, pages = {315 -- 321}, year = {2013}, abstract = {The chemical imaging sensor is a semiconductor-based chemical sensor that can visualize the spatial distribution of specific ions on the sensing surface. The conventional chemical imaging system based on the light-addressable potentiometric sensor (LAPS), however, required a long time to obtain a chemical image, due to the slow mechanical scan of a single light beam. For high-speed imaging, a plurality of light beams modulated at different frequencies can be employed to measure the ion concentrations simultaneously at different locations on the sensor plate by frequency division multiplex (FDM). However, the conventional measurement geometry of back-side illumination limited the bandwidth of the modulation frequency required for FDM measurement, because of the low-pass filtering characteristics of carrier diffusion in the Si substrate. In this study, a high-speed chemical imaging system based on front-side-illuminated LAPS was developed, which achieved high-speed spatiotemporal recording of pH change at a rate of 70 frames per second.}, language = {en} } @article{IkenAhlbornGerlachetal.2013, author = {Iken, Heiko and Ahlborn, K. and Gerlach, F. and Vonau, W. and Zander, W. and Schubert, J. and Sch{\"o}ning, Michael Josef}, title = {Development of redox glasses and subsequent processing by means of pulsed laser deposition for realizing silicon-based thin-film sensors}, series = {Electrochimica acta}, journal = {Electrochimica acta}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-3859 (E-Journal); 0013-4686 (Print)}, pages = {Available online 30.8.2013}, year = {2013}, language = {en} } @article{Laack2013, author = {Laack, Walter van}, title = {Ist der Tod das Ende? In: Sterben - wie f{\"u}hlt sich das an / Ines Elsenhans}, series = {Via medici : Fachmagazin f{\"u}r junge Mediziner}, volume = {Vol. 18}, journal = {Via medici : Fachmagazin f{\"u}r junge Mediziner}, number = {Ausg. 5}, publisher = {Thieme}, address = {Stuttgart}, issn = {0949-2488}, pages = {38}, year = {2013}, language = {de} } @article{Laack2013, author = {Laack, Walter van}, title = {Why natural constants are as they are}, series = {British journal of arts and social sciences}, volume = {Vol. 15}, journal = {British journal of arts and social sciences}, number = {Nr. 2}, publisher = {BritishJournal Publ. Inc}, address = {London}, issn = {2046-9578 (E-Journal)}, pages = {198 -- 203}, year = {2013}, language = {en} } @article{Staat2013, author = {Staat, Manfred}, title = {Limit and shakedown analysis under uncertainty}, series = {International journal of computational methods : IJCM}, journal = {International journal of computational methods : IJCM}, publisher = {World Scientific Publishing}, address = {Singapore}, issn = {0219-8762}, pages = {Publ. online}, year = {2013}, language = {en} } @inproceedings{FrotscherGossmannTemizArtmannetal.2013, author = {Frotscher, Ralf and Goßmann, Matthias and Temiz Artmann, Ayseg{\"u}l and Staat, Manfred}, title = {Simulation of cardiac cell-seeded membranes using the edge-based smoothed FEM}, series = {1st International Conference "Shell and Membrane Theories in Mechanics and Biology: From Macro- to Nanoscale Structures", Minsk, Belarus, Sept. 16-20, 2013}, booktitle = {1st International Conference "Shell and Membrane Theories in Mechanics and Biology: From Macro- to Nanoscale Structures", Minsk, Belarus, Sept. 16-20, 2013}, publisher = {Verl. d. Weißruss. Staatl. Univ.}, address = {Minsk}, organization = {International Conference Shell and Membrane Theories in Mechanics and Biology: From Macro- to Nanoscale Structures <1, 2013, Minsk>}, isbn = {978-985-553-135-8}, pages = {165 -- 167}, year = {2013}, language = {en} } @article{Laack2013, author = {Laack, Walter van}, title = {Our world is well ordered in measurement and number : or why natural constants are as they are}, series = {American Journal of Humanities and Social Sciences (AHSS)}, volume = {1}, journal = {American Journal of Humanities and Social Sciences (AHSS)}, number = {4}, issn = {2329-079X}, doi = {10.11634/232907811301390}, pages = {219 -- 221}, year = {2013}, abstract = {All the important natural constants can be logically explained with and derived from the first four ordinal numbers, 1, 2, 3 and 4, its addition to ten and finally the standard values for obviously maximal feasibility Ω and the optimum in our world, the Golden Section (GS), i.e. the number sequences 273 and 618. They both are the first three numbers of irrational results by an arithmetical transformation of simple geometrical relationships by creating multiplicity out of singularity. Both of them show that the infinite is inherent in finiteness and explain in a simple way the smallest deviations and fluctuations between the physical AS-IS state and the obvious spiritual ideal behind: Wherever we look in this world, and especially in important key-positions, we regularly find these sequences. All of the above mentioned numbers so seem to be key players in our world, what can be demonstrated by the derivation of natural constants.}, language = {en} } @article{ReisertGeisslerFloerkeetal.2013, author = {Reisert, Steffen and Geissler, Hanno and Fl{\"o}rke, Rudolf and Weiler, Christian and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Characterisation of aseptic sterilisation processes using an electronic nose}, series = {International journal of nanotechnology}, volume = {Vol. 10}, journal = {International journal of nanotechnology}, number = {No. 5-7}, publisher = {Inderscience Enterprises}, address = {Gen{\`e}ve}, issn = {1475-7435 (Print) 7141-8151 (Online)}, pages = {470 -- 484}, year = {2013}, language = {en} } @article{JungStaatMueller2013, author = {Jung, Alexander and Staat, Manfred and M{\"u}ller, Wolfram}, title = {Flight style optimization in ski jumping on normal, large, and ski flying hills}, series = {Journal of biomechanics}, volume = {Vol. 47}, journal = {Journal of biomechanics}, number = {Iss. 3}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-2380 (E-Journal); 0021-9290 (Print)}, pages = {716 -- 722}, year = {2013}, language = {en} } @article{MiyamotoHirayamaWagneretal.2013, author = {Miyamoto, Ko-ichiro and Hirayama, Yuji and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo}, title = {Visualization of enzymatic reaction in a microfluidic channel using chemical imaging sensor}, series = {Electrochimica acta}, journal = {Electrochimica acta}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-3859 (E-Journal); 0013-4686 (Print)}, pages = {Publ. online}, year = {2013}, language = {en} } @misc{IngebrandtWagnerSchoening2013, author = {Ingebrandt, Sven and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Engineering of functional interfaces / guest eds. Sven Ingebrandt ; Patrick Wagner ; Michael J. Sch{\"o}ning}, series = {Physica Status Solidi (A)}, volume = {Vol. 210}, journal = {Physica Status Solidi (A)}, number = {Iss. 5}, issn = {1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)}, pages = {845}, year = {2013}, language = {en} } @article{MiciliValterOflazetal.2013, author = {Micili, Serap C. and Valter, Markus and Oflaz, Hakan and Ozogul, Candan and Linder, Peter and F{\"o}ckler, Nicole and Artmann, Gerhard and Digel, Ilya and Temiz Artmann, Ayseg{\"u}l}, title = {Optical coherence tomography : a potential tool to predict premature rupture of fetal membranes}, series = {Proceedings of the Institution of Mechanical Engineers. Part H : Journal of engineering in medicine}, volume = {Vol. 227}, journal = {Proceedings of the Institution of Mechanical Engineers. Part H : Journal of engineering in medicine}, number = {No. 4}, publisher = {Sage}, address = {London}, issn = {0046-2039 (Print) ; 2041-3033 (E-Journal)}, pages = {393 -- 401}, year = {2013}, language = {en} } @misc{AbdelghaniMenaaObareetal.2013, author = {Abdelghani, Adnane and Menaa, Bouzid and Obare, Sherine O. and Sch{\"o}ning, Michael Josef}, title = {Special issue on nanoscale science and technology / guest eds.: Adnane Abdelghani, Bouzid Menaa, Sherine O. Obare, Michael J. Sch{\"o}ning}, series = {International journal of nanotechnology}, volume = {Vol. 10}, journal = {International journal of nanotechnology}, number = {No. 5-7}, issn = {1741-8151 (E-Journal), 1475-7435 (Print)}, pages = {373 -- 619}, year = {2013}, language = {en} } @article{BaeckerSchusserPoghossianetal.2013, author = {B{\"a}cker, Matthias and Schusser, Sebastian and Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Degradationsverhalten bioabbaubarer Polymere : siliziumbasierte Sensorik zur {\"U}berwachung}, series = {GIT Labor-Fachzeitschrift}, journal = {GIT Labor-Fachzeitschrift}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0016-3538}, pages = {32 -- 33}, year = {2013}, language = {de} }