@article{MolinnusMuschallikGonzalezetal.2018, author = {Molinnus, Denise and Muschallik, Lukas and Gonzalez, Laura Osorio and Bongaerts, Johannes and Wagner, Torsten and Selmer, Thorsten and Siegert, Petra and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Development and characterization of a field-effect biosensor for the detection of acetoin}, series = {Biosensors and Bioelectronics}, volume = {115}, journal = {Biosensors and Bioelectronics}, publisher = {Elsevier}, address = {Amsterdam}, doi = {10.1016/j.bios.2018.05.023}, pages = {1 -- 6}, year = {2018}, abstract = {A capacitive electrolyte-insulator-semiconductor (EIS) field-effect biosensor for acetoin detection has been presented for the first time. The EIS sensor consists of a layer structure of Al/p-Si/SiO₂/Ta₂O₅/enzyme acetoin reductase. The enzyme, also referred to as butane-2,3-diol dehydrogenase from B. clausii DSM 8716T, has been recently characterized. The enzyme catalyzes the (R)-specific reduction of racemic acetoin to (R,R)- and meso-butane-2,3-diol, respectively. Two different enzyme immobilization strategies (cross-linking by using glutaraldehyde and adsorption) have been studied. Typical biosensor parameters such as optimal pH working range, sensitivity, hysteresis, linear concentration range and long-term stability have been examined by means of constant-capacitance (ConCap) mode measurements. Furthermore, preliminary experiments have been successfully carried out for the detection of acetoin in diluted white wine samples.}, language = {en} } @inproceedings{KoenigVoelkerWolf2018, author = {K{\"o}nig, Johannes Alexander and V{\"o}lker, Veronika and Wolf, Martin R.}, title = {The user-focused storybuilding framework for competence developing games - a design-framework considering the basics of an educational game's story}, series = {ACHI 2018 : The Eleventh International Conference on Advances in Computer-Human Interactions}, booktitle = {ACHI 2018 : The Eleventh International Conference on Advances in Computer-Human Interactions}, isbn = {978-1-61208-616-3}, pages = {98 -- 106}, year = {2018}, abstract = {During the development of a Competence Developing Game's (CDG) story it is indispensable to understand the target audience. Thereby, CDGs stories represent more than just the plot. The Story is about the Setting, the Characters and the Plot. As a toolkit to support the development of such a story, this paper introduces the UserFocused Storybuilding (short UFoS) Framework for CDGs. The Framework and its utilization will be explained, followed by a description of its development and derivation, including an empirical study. In addition, to simplify the Framework use regarding the CDG's target audience, a new concept of Nine Psychographic Player Types will be explained. This concept of Player Types provides an approach to handle the differences in between players during the UFoS Framework use. Thereby, this article presents a unique approach to the development of target group-differentiated CDGs stories.}, language = {en} } @inproceedings{GrundmannBauerBieleetal.2018, author = {Grundmann, Jan Thimo and Bauer, Waldemar and Biele, Jens and Boden, Ralf and Ceriotti, Matteo and Cordero, Federico and Dachwald, Bernd and Dumont, Etienne and Grimm, Christian D. and Herč{\´i}k, David and Ho, Tra-Mi and Jahnke, Rico and Koch, Aaron D and Koncz, Alexander and Krause, Christian and Lange, Caroline and Lichtenheldt, Roy and Maiwald, Volker and Mikschl, Tobias and Mikulz, Eugen and Montenegro, Sergio and Pelivan, Ivanka and Peloni, Alessandro and Quantius, Dominik and Reershemius, Siebo and Renger, Thomas and Riemann, Johannes and Ruffer, Michael and Sasaki, Kaname and Schmitz, Nicole and Seboldt, Wolfgang and Seefeldt, Patric and Spietz, Peter and Spr{\"o}witz, Tom and Sznajder, Maciej and Tardivel, Simon and T{\´o}th, Norbert and Wejmo, Elisabet and Wolff, Friederike and Ziach, Christian}, title = {Small spacecraft based multiple near-earth asteroid rendezvous and landing with near-term solar sails and 'Now-Term 'technologies}, series = {69 th International Astronautical Congress (IAC)}, booktitle = {69 th International Astronautical Congress (IAC)}, pages = {1 -- 18}, year = {2018}, abstract = {Physical interaction with small solar system bodies (SSSB) is the next step in planetary science, planetary in-situ resource utilization (ISRU), and planetary defense (PD). It requires a broader understanding of the surface properties of the target objects, with particular interest focused on those near Earth. Knowledge of composition, multi-scale surface structure, thermal response, and interior structure is required to design, validate and operate missions addressing these three fields. The current level of understanding is occasionally simplified into the phrase, "If you've seen one asteroid, you've seen one asteroid", meaning that the in-situ characterization of SSSBs has yet to cross the threshold towards a robust and stable scheme of classification. This would enable generic features in spacecraft design, particularly for ISRU and science missions. Currently, it is necessary to characterize any potential target object sufficiently by a dedicated pre-cursor mission to design the mission which then interacts with the object in a complex fashion. To open up strategic approaches, much broader in-depth characterization of potential target objects would be highly desirable. In SSSB science missions, MASCOT-like nano-landers and instrument carriers which integrate at the instrument level to their mothership have met interest. By its size, MASCOT is compatible with small interplanetary missions. The DLR-ESTEC Gossamer Roadmap Science Working Groups' studies identified Multiple Near-Earth asteroid (NEA) Rendezvous (MNR) as one of the space science missions only feasible with solar sail propulsion. The Solar Polar Orbiter (SPO) study showed the ability to access any inclination, theDisplaced-L1 (DL1) mission operates close to Earth, where objects of interest to PD and for ISRU reside. Other studies outline the unique capability of solar sails to provide access to all SSSB, at least within the orbit of Jupiter, and significant progress has been made to explore the performance envelope of near-term solar sails for MNR. However, it is difficult for sailcraft to interact physically with a SSSB. We expand and extend the philosophy of the recently qualified DLR Gossamer solar sail deployment technology using efficient multiple sub-spacecraft integration to also include landers for one-way in-situ investigations and sample-return missions by synergetic integration and operation of sail and lander. The MASCOT design concept and its characteristic features have created an ideal counterpart for thisand has already been adapted to the needs of the AIM spacecraft, former part of the NASA-ESA AIDA missionDesigning the 69th International Astronautical Congress (IAC), Bremen, Germany, 1-5 October 2018. IAC-18-F1.2.3 Page 2 of 17 combined spacecraft for piggy-back launch accommodation enables low-cost massively parallel access to the NEA population.}, language = {en} } @inproceedings{AnicPenavaGuljasetal.2018, author = {Anic, Filip and Penava, Davorin and Guljas, Ivica and Sarhosis, Vasilis and Abrahamczyk, Lars and Butenweg, Christoph}, title = {The Effect of Openings on Out-of-Plane Capacity of Masonry Infilled Reinforced Concrete Frames}, series = {16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018}, booktitle = {16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018}, pages = {1 -- 11}, year = {2018}, language = {en} } @article{MichelButenwegKinkel2018, author = {Michel, Philipp and Butenweg, Christoph and Kinkel, Sven}, title = {Pile-grid foundations of onshore wind turbines considering soil-structure-interaction under seismic loading}, series = {Soil Dynamics and Earthquake Engineering}, volume = {109}, journal = {Soil Dynamics and Earthquake Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0267-7261}, doi = {10.1016/j.soildyn.2018.03.009}, pages = {299 -- 311}, year = {2018}, abstract = {In recent years, many onshore wind turbines are erected in seismic active regions and on soils with poor load bearing capacity, where pile grids are inevitable to transfer the loads into the ground. In this contribution, a realistic multi pile grid is designed to analyze the dynamics of a wind turbine tower including frequency dependent soil-structure-interaction. It turns out that different foundations on varying soil configurations heavily influence the vibration response. While the vibration amplitude is mostly attenuated, certain unfavorable combinations of structure and soil parameters lead to amplification in the range of the system's natural frequencies. This testifies the need for overall dynamic analysis in the assessment of the dynamic stability and the holistic frequency tuning of the turbines.}, language = {en} } @article{RosinButenwegCacciatoreetal.2018, author = {Rosin, Julia and Butenweg, Christoph and Cacciatore, Pamela and Boesen, Niklas}, title = {Investigation of the seismic performance of modern masonry buildings during the Emilia Romagna earthquake series}, series = {Mauerwerk}, volume = {22}, journal = {Mauerwerk}, number = {4}, publisher = {Ernst \& Sohn}, address = {Berlin}, issn = {1437-1022}, doi = {10.1002/dama.201800013}, pages = {238 -- 250}, year = {2018}, abstract = {The article presents the investigation of the seismic behaviour of a modern URM building located in the municipality of Finale Emilia in province of Modena, Northern Italy. The building is situated in the centre of the series of the 2012 Northern Italy earthquakes and has not suffered any damage during the earthquake series in 2012. The observed earthquake resistance of the building is compared with predicted resistances based on linear and nonlinear design approaches according to Eurocode. Furthermore, probabilistic analyses based on nonlinear calculation models taking into account scattering of the most relevant input parameters are carried out to identify their influence to the results and to derive fragility curves.}, language = {en} } @inproceedings{GoettenHavermannBraunetal.2018, author = {G{\"o}tten, Falk and Havermann, Marc and Braun, Carsten and Gomez, Francisco and Bil, Cees}, title = {On the Applicability of Empirical Drag Estimation Methods for Unmanned Air Vehicle Design Read More: https://arc.aiaa.org/doi/10.2514/6.2018-3192}, series = {2018 Aviation Technology, Integration, and Operations Conference, AIAA AVIATION Forum}, booktitle = {2018 Aviation Technology, Integration, and Operations Conference, AIAA AVIATION Forum}, issn = {1533-385X}, doi = {10.2514/6.2018-3192}, pages = {Article 3192}, year = {2018}, language = {en} } @inproceedings{ValeroVogelSchmidtetal.2018, author = {Valero, Daniel and Vogel, Jochen and Schmidt, Daniel and Bung, Daniel Bernhard}, title = {Three-dimensional flow structure inside the cavity of a non-aerated stepped chute}, series = {7th IAHR International Symposium on Hydraulic Structures, Aachen, Germany, 15-18 May}, booktitle = {7th IAHR International Symposium on Hydraulic Structures, Aachen, Germany, 15-18 May}, isbn = {978-0-692-13277-7}, doi = {10.15142/T3GH17}, pages = {12 Seiten}, year = {2018}, language = {en} } @article{CiritsisHorbachStaatetal.2018, author = {Ciritsis, Alexander and Horbach, Andreas and Staat, Manfred and Kuhl, Christiane K. and Kraemer, Nils Andreas}, title = {Porosity and tissue integration of elastic mesh implants evaluated in vitro and in vivo}, series = {Journal of Biomedical Materials Research: Part B: Applied Biomaterials}, volume = {106}, journal = {Journal of Biomedical Materials Research: Part B: Applied Biomaterials}, number = {2}, publisher = {Wiley}, address = {New York, NY}, issn = {1552-4981}, doi = {10.1002/jbm.b.33877}, pages = {827 -- 833}, year = {2018}, abstract = {Purpose In vivo, a loss of mesh porosity triggers scar tissue formation and restricts functionality. The purpose of this study was to evaluate the properties and configuration changes as mesh deformation and mesh shrinkage of a soft mesh implant compared with a conventional stiff mesh implant in vitro and in a porcine model. Material and Methods Tensile tests and digital image correlation were used to determine the textile porosity for both mesh types in vitro. A group of three pigs each were treated with magnetic resonance imaging (MRI) visible conventional stiff polyvinylidene fluoride meshes (PVDF) or with soft thermoplastic polyurethane meshes (TPU) (FEG Textiltechnik mbH, Aachen, Germany), respectively. MRI was performed with a pneumoperitoneum at a pressure of 0 and 15 mmHg, which resulted in bulging of the abdomen. The mesh-induced signal voids were semiautomatically segmented and the mesh areas were determined. With the deformations assessed in both mesh types at both pressure conditions, the porosity change of the meshes after 8 weeks of ingrowth was calculated as an indicator of preserved elastic properties. The explanted specimens were examined histologically for the maturity of the scar (collagen I/III ratio). Results In TPU, the in vitro porosity increased constantly, in PVDF, a loss of porosity was observed under mild stresses. In vivo, the mean mesh areas of TPU were 206.8 cm2 (± 5.7 cm2) at 0 mmHg pneumoperitoneum and 274.6 cm2 (± 5.2 cm2) at 15 mmHg; for PVDF the mean areas were 205.5 cm2 (± 8.8 cm2) and 221.5 cm2 (± 11.8 cm2), respectively. The pneumoperitoneum-induced pressure increase resulted in a calculated porosity increase of 8.4\% for TPU and of 1.2\% for PVDF. The mean collagen I/III ratio was 8.7 (± 0.5) for TPU and 4.7 (± 0.7) for PVDF. Conclusion The elastic properties of TPU mesh implants result in improved tissue integration compared to conventional PVDF meshes, and they adapt more efficiently to the abdominal wall. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 827-833, 2018.}, language = {en} } @inproceedings{TranMatthiesStavroulakisetal.2018, author = {Tran, Ngoc Trinh and Matthies, Hermann G. and Stavroulakis, Georgios Eleftherios and Staat, Manfred}, title = {Direct plastic structural design by chance constrained programming}, series = {6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK}, booktitle = {6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK}, pages = {12 Seiten}, year = {2018}, abstract = {We propose a stochastic programming method to analyse limit and shakedown of structures under random strength with lognormal distribution. In this investigation a dual chance constrained programming algorithm is developed to calculate simultaneously both the upper and lower bounds of the plastic collapse limit or the shakedown limit. The edge-based smoothed finite element method (ES-FEM) using three-node linear triangular elements is used.}, language = {en} } @incollection{ArtmannMeruvuKizildagetal.2018, author = {Artmann, Gerhard and Meruvu, Haritha and Kizildag, Sefa and Temiz Artmann, Ayseg{\"u}l}, title = {Functional Toxicology and Pharmacology Test of Cell Induced Mechanical Tensile Stress in 2D and 3D Tissue Cultures}, series = {Biological, Physical and Technical Basics of Cell Engineering}, booktitle = {Biological, Physical and Technical Basics of Cell Engineering}, editor = {Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Zhubanova, Azhar A. and Digel, Ilya}, publisher = {Springer}, address = {Singapore}, isbn = {978-981-10-7904-7}, doi = {10.1007/978-981-10-7904-7_7}, pages = {157 -- 192}, year = {2018}, abstract = {Mechanical forces/tensile stresses are critical determinants of cellular growth, differentiation and migration patterns in health and disease. The innovative "CellDrum technology" was designed for measuring mechanical tensile stress of cultured cell monolayers/thin tissue constructs routinely. These are cultivated on very thin silicone membranes in the so-called CellDrum. The cell layers adhere firmly to the membrane and thus transmit the cell forces generated. A CellDrum consists of a cylinder which is sealed from below with a 4 μm thick, biocompatible, functionalized silicone membrane. The weight of cell culture medium bulbs the membrane out downwards. Membrane indentation is measured. When cells contract due to drug action, membrane, cells and medium are lifted upwards. The induced indentation changes allow for lateral drug induced mechanical tension quantification of the micro-tissues. With hiPS-induced (human) Cardiomyocytes (CM) the CellDrum opens new perspectives of individualized cardiac drug testing. Here, monolayers of self-beating hiPS-CMs were grown in CellDrums. Rhythmic contractions of the hiPS-cells induce membrane up-and-down deflections. The recorded cycles allow for single beat amplitude, single beat duration, integration of the single beat amplitude over the beat time and frequency analysis. Dose effects of agonists and antagonists acting on Ca2+ channels were sensitively and highly reproducibly observed. Data were consistent with published reference data as far as they were available. The combination of the CellDrum technology with hiPS-Cardiomyocytes offers a fast, facile and precise system for pharmacological and toxicological studies. It allows new preclinical basic as well as applied research in pharmacolgy and toxicology.}, language = {en} } @inproceedings{KahmannUschokWegmannetal.2018, author = {Kahmann, Stephanie Lucina and Uschok, Stephan and Wegmann, Kilian and M{\"u}ller, Lars-P. and Staat, Manfred}, title = {Biomechanical multibody model with refined kinematics of the elbow}, series = {6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK}, booktitle = {6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK}, pages = {11 Seiten}, year = {2018}, abstract = {The overall objective of this study is to develop a new external fixator, which closely maps the native kinematics of the elbow to decrease the joint force resulting in reduced rehabilitation time and pain. An experimental setup was designed to determine the native kinematics of the elbow during flexion of cadaveric arms. As a preliminary study, data from literature was used to modify a published biomechanical model for the calculation of the joint and muscle forces. They were compared to the original model and the effect of the kinematic refinement was evaluated. Furthermore, the obtained muscle forces were determined in order to apply them in the experimental setup. The joint forces in the modified model differed slightly from the forces in the original model. The muscle force curves changed particularly for small flexion angles but their magnitude for larger angles was consistent.}, language = {en} } @inproceedings{HofmannMatareSchifferetal.2018, author = {Hofmann, Till and Matar{\´e}, Victor and Schiffer, Stefan and Ferrein, Alexander and Lakemeyer, Gerhard}, title = {Constraint-based online transformation of abstract plans into executable robot actions}, series = {Proceedings of the 2018 AAAI Spring Symposium on Integrating Representation, Reasoning, Learning, and Execution for Goal Directed Autonomy}, booktitle = {Proceedings of the 2018 AAAI Spring Symposium on Integrating Representation, Reasoning, Learning, and Execution for Goal Directed Autonomy}, pages = {549 -- 553}, year = {2018}, language = {en} } @inproceedings{WaldmannVeraDachwaldetal.2018, author = {Waldmann, Christoph and Vera, Jean-Pierre de and Dachwald, Bernd and Strasdeit, Henry and Sohl, Frank and Hanff, Hendrik and Kowalski, Julia and Heinen, Dirk and Macht, Sabine and Bestmann, Ulf and Meckel, Sebastian and Hildebrandt, Marc and Funke, Oliver and Gehrt, Jan-J{\"o}ran}, title = {Search for life in ice-covered oceans and lakes beyond Earth}, series = {2018 IEEE/OES Autonomous Underwater Vehicle Workshop, Proceedings November 2018, Article number 8729761}, booktitle = {2018 IEEE/OES Autonomous Underwater Vehicle Workshop, Proceedings November 2018, Article number 8729761}, doi = {10.1109/AUV.2018.8729761}, year = {2018}, abstract = {The quest for life on other planets is closely connected with the search for water in liquid state. Recent discoveries of deep oceans on icy moons like Europa and Enceladus have spurred an intensive discussion about how these waters can be accessed. The challenge of this endeavor lies in the unforeseeable requirements on instrumental characteristics both with respect to the scientific and technical methods. The TRIPLE/nanoAUV initiative is aiming at developing a mission concept for exploring exo-oceans and demonstrating the achievements in an earth-analogue context, exploring the ocean under the ice shield of Antarctica and lakes like Dome-C on the Antarctic continent.}, language = {en} } @incollection{BhattaraiFrotscherStaat2018, author = {Bhattarai, Aroj and Frotscher, Ralf and Staat, Manfred}, title = {Computational Analysis of Pelvic Floor Dysfunction}, series = {Women's Health and Biomechanics}, booktitle = {Women's Health and Biomechanics}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-71574-2}, doi = {10.1007/978-3-319-71574-2_17}, pages = {217 -- 230}, year = {2018}, abstract = {Pelvic floor dysfunction (PFD) is characterized by the failure of the levator ani (LA) muscle to maintain the pelvic hiatus, resulting in the descent of the pelvic organs below the pubococcygeal line. This chapter adopts the modified Humphrey material model to consider the effect of the muscle fiber on passive stretching of the LA muscle. The deformation of the LA muscle subjected to intra-abdominal pressure during Valsalva maneuver is compared with the magnetic resonance imaging (MRI) examination of a nulliparous female. Numerical result shows that the fiber-based Humphrey model simulates the muscle behavior better than isotropic constitutive models. Greater posterior movement of the LA muscle widens the levator hiatus due to lack of support from the anococcygeal ligament and the perineal structure as a consequence of birth-related injury and aging. Old and multiparous females with uncontrolled urogenital and rectal hiatus tend to develop PFDs such as prolapse and incontinence.}, language = {en} } @inproceedings{FingerGoettenBraun2018, author = {Finger, Felix and G{\"o}tten, Falk and Braun, Carsten}, title = {Initial Sizing for a Family of Hybrid-Electric VTOL General Aviation Aircraft}, series = {67. Deutscher Luft- und Raumfahrtkongress 2018}, booktitle = {67. Deutscher Luft- und Raumfahrtkongress 2018}, pages = {14 S.}, year = {2018}, language = {en} } @article{ValeroBungCrookston2018, author = {Valero, Daniel and Bung, Daniel Bernhard and Crookston, B.M.}, title = {Energy dissipation of a Type III basin under design and adverse conditions for stepped and smooth spillways}, series = {Journal of Hydraulic Engineering}, volume = {144}, journal = {Journal of Hydraulic Engineering}, number = {7}, publisher = {ASCE}, address = {Reston, Va.}, issn = {0733-9429}, doi = {10.1061/(ASCE)HY.1943-7900.0001482}, year = {2018}, abstract = {New information regarding the influence of a stepped chute on the hydraulic performance of the United States Bureau of Reclamation (Reclamation) Type III hydraulic jump stilling basin is presented for design (steady) and adverse (decreasing tailwater) conditions. Using published experimental data and computational fluid dynamics (CFD) models, this paper presents a detailed comparison between smooth-chute and stepped-chute configurations for chute slopes of 0.8H:1V and 4H:1V and Froude numbers (F) ranging from 3.1 to 9.5 for a Type III basin designed for F = 8. For both stepped and smooth chutes, the relative role of each basin element was quantified, up to the most hydraulic extreme case of jump sweep-out. It was found that, relative to a smooth chute, the turbulence generated by a stepped chute causes a higher maximum velocity decay within the stilling basin, which represents an enhancement of the Type III basin's performance but also a change in the relative role of the basin elements. Results provide insight into the ability of the CFD models [unsteady Reynolds-averaged Navier-Stokes (RANS) equations with renormalization group (RNG) k-ϵ turbulence model and volume-of-fluid (VOF) for free surface tracking] to predict the transient basin flow structure and velocity profiles. Type III basins can perform adequately with a stepped chute despite the effects steps have on the relative role of each basin element. It is concluded that the classic Type III basin design, based upon methodology by reclamation specific to smooth chutes, can be hydraulically improved for the case of stepped chutes for design and adverse flow conditions using the information presented herein.}, language = {en} } @article{TeumerCapitainRossJonesetal.2018, author = {Teumer, T. and Capitain, C. and Ross-Jones, J. and Tippk{\"o}tter, Nils and R{\"a}dle, M. and Methner, F.-J.}, title = {In-line Haze Monitoring Using a Spectrally Resolved Back Scattering Sensor}, series = {BrewingScience}, volume = {71}, journal = {BrewingScience}, number = {5/6}, publisher = {Fachverlag Hans Carl}, address = {N{\"u}rnberg}, issn = {1613-2041}, pages = {49 -- 55}, year = {2018}, abstract = {In the present work an optical sensor in combination with a spectrally resolved detection device for in-line particle-size-monitoring for quality control in beer production is presented. The principle relies on the size and wavelength dependent backscatter of growing particles in fluids. Measured interference structures of backscattered light are compared with calculated theoretical values, based on Mie-Theory, and fitted with a linear least square method to obtain particle size distributions. For this purpose, a broadband light source in combination with a process-CCD-spectrometer (charge ? coupled device spectrometer) and process adapted fiber optics are used. The goal is the development of an easy and flexible measurement device for in-line-monitoring of particle size. The presented device can be directly installed in product fill tubes or vessels, follows CIP- (cleaning in place) and removes the need of sample taking. A proof of concept and preliminary results, measuring protein precipitation, are presented.}, language = {en} } @incollection{SchoeningWagnerPoghossianetal.2018, author = {Sch{\"o}ning, Michael Josef and Wagner, Torsten and Poghossian, Arshak and Miyamoto, K.I. and Werner, C.F. and Krause, S. and Yoshinobu, T.}, title = {Light-addressable potentiometric sensors for (bio-)chemical sensing and imaging}, series = {Encyclopedia of Interfacial Chemistry: Surface Science and Electrochemistry. Vol. 7}, booktitle = {Encyclopedia of Interfacial Chemistry: Surface Science and Electrochemistry. Vol. 7}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {9780128097397}, pages = {295 -- 308}, year = {2018}, language = {en} } @article{ValeroBung2018, author = {Valero, Daniel and Bung, Daniel Bernhard}, title = {Vectrino profiler spatial filtering for shear flows based on the mean velocity gradient equation}, series = {Journal of Hydraulic Engineering}, volume = {144}, journal = {Journal of Hydraulic Engineering}, number = {7}, publisher = {ASCE}, address = {Reston, Va.}, issn = {0733-9429}, doi = {10.1061/(ASCE)HY.1943-7900.0001485}, year = {2018}, abstract = {A new methodology is proposed to spatially filter acoustic Doppler velocimetry data from a Vectrino profiler based on the differential mean velocity equation. Lower and upper bounds are formulated in terms of physically based flow constraints. Practical implementation is discussed, and its application is tested against data gathered from an open-channel flow over a stepped macroroughness surface. The method has proven to detect outliers occurring all over the distance range sampled by the Vectrino profiler and has shown to remain applicable out of the region of validity of the velocity gradient equation. Finally, a statistical analysis suggests that physically obtained bounds are asymptotically representative.}, language = {en} }