@article{GuoSekiMiyamotoetal.2014, author = {Guo, Yuanyuan and Seki, Kosuke and Miyamoto, Ko-ichiro and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo}, title = {Device simulation of the light-addressable potentiometric sensor with a novel photoexcitation method for a higher spatial resolution}, series = {Procedia Engineering}, volume = {87}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2014.11.369}, pages = {456 -- 459}, year = {2014}, abstract = {A novel photoexcitation method for the light-addressable potentiometric sensor (LAPS) realized a higher spatial resolution of chemical imaging. In this method, a modulated light probe, which generates the alternating photocurrent signal, is surrounded by a ring of constant light, which suppresses the lateral diffusion of photocarriers by enhancing recombination. A device simulation verified that a higher spatial resolution could be obtained by adjusting the gap between the modulated and constant light. It was also found that a higher intensity and a longer wavelength of constant light was more effective. However, there exists a tradeoff between the spatial resolution and the amplitude of the photocurrent, and thus, the signal-to-noise ratio. A tilted incidence of constant light was applied, which could achieve even higher resolution with a smaller loss of photocurrent.}, language = {en} } @article{MiyamotoSekiWagneretal.2014, author = {Miyamoto, K. and Seki, K. and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, T.}, title = {Enhancement of the spatial resolution of the chemical imaging sensor by a hybrid fiber-optic illumination}, series = {Procedia Engineering}, volume = {87}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2014.11.563}, pages = {612 -- 615}, year = {2014}, abstract = {The chemical imaging sensor, which is based on the principle of the light-addressable potentiometric sensor (LAPS), is a powerful tool to visualize the spatial distribution of chemical species on the sensor surface. The spatial resolution of this sensor depends on the diffusion of photocarriers excited by a modulated light. In this study, a novel hybrid fiber-optic illumination was developed to enhance the spatial resolution. It consists of a modulated light probe to generate a photocurrent signal and a ring of constant light, which suppresses the lateral diffusion of minority carriers excited by the modulated light. It is demonstrated that the spatial resolution was improved from 92 μm to 68 μm.}, language = {en} } @article{AlmajhdiSengerAmeretal.2014, author = {Almajhdi, Fahad N. and Senger, Tilo and Amer, Haitham M. and Gissmann, Lutz and {\"O}hlschl{\"a}ger, Peter}, title = {Design of a highly effective therapeutic HPV16 E6/E7-specific DNA vaccine: optimization by different ways of sequence rearrangements (Shuffling)}, series = {PLOS one}, volume = {11}, journal = {PLOS one}, number = {9}, publisher = {PLOS}, address = {San Francisco}, issn = {1932-6203}, doi = {10.1371/journal.pone.0113461}, pages = {e113461}, year = {2014}, abstract = {Persistent infection with the high-risk Human Papillomavirus type 16 (HPV 16) is the causative event for the development of cervical cancer and other malignant tumors of the anogenital tract and of the head and neck. Despite many attempts to develop therapeutic vaccines no candidate has entered late clinical trials. An interesting approach is a DNA based vaccine encompassing the nucleotide sequence of the E6 and E7 viral oncoproteins. Because both proteins are consistently expressed in HPV infected cells they represent excellent targets for immune therapy. Here we report the development of 8 DNA vaccine candidates consisting of differently rearranged HPV-16 E6 and E7 sequences within one molecule providing all naturally occurring epitopes but supposedly lacking transforming activity. The HPV sequences were fused to the J-domain and the SV40 enhancer in order to increase immune responses. We demonstrate that one out of the 8 vaccine candidates induces very strong cellular E6- and E7- specific cellular immune responses in mice and, as shown in regression experiments, efficiently controls growth of HPV 16 positive syngeneic tumors. This data demonstrates the potential of this vaccine candidate to control persistent HPV 16 infection that may lead to malignant disease. It also suggests that different sequence rearrangements influence the immunogenecity by an as yet unknown mechanism.}, language = {en} } @article{MathiakPlescherWillnecker2005, author = {Mathiak, Gerhard and Plescher, Engelbert and Willnecker, Rainer}, title = {Liquid metal diffusion experiments in microgravity - Vibrational effects}, series = {Measurement science and technology}, volume = {Vol. 16}, journal = {Measurement science and technology}, number = {No. 2}, issn = {0957-0233}, doi = {10.1088/0957-0233/16/2/003}, pages = {336}, year = {2005}, language = {en} } @article{MathiakWillneckerPlescher2005, author = {Mathiak, Gerhard and Willnecker, Rainer and Plescher, Engelbert}, title = {Vibrational effects on diffusion experiments}, series = {Microgravity science and technology : international journal for microgravity research and applications}, volume = {Vol. 15}, journal = {Microgravity science and technology : international journal for microgravity research and applications}, number = {No. 1}, issn = {0938-0108}, pages = {295 -- 300}, year = {2005}, language = {en} } @article{FateriGebhardt2015, author = {Fateri, Miranda and Gebhardt, Andreas}, title = {Selective Laser Melting of Soda-Lime Glass Powder}, series = {International Journal of Applied Ceramic Technology}, volume = {12}, journal = {International Journal of Applied Ceramic Technology}, number = {1}, publisher = {Wiley-Blackwell}, address = {Oxford}, issn = {1744-7402}, doi = {10.1111/ijac.12338}, pages = {53 -- 61}, year = {2015}, language = {en} } @article{FateriGebhardt2015, author = {Fateri, Miranda and Gebhardt, Andreas}, title = {Process Parameters Development of Selective Laser Melting of Lunar Regolith for On-Site Manufacturing Applications}, series = {International Journal of Applied Ceramic Technology}, volume = {12}, journal = {International Journal of Applied Ceramic Technology}, number = {1}, publisher = {Wiley-Blackwell}, address = {Oxford}, isbn = {1744-7402}, doi = {10.1111/ijac.12326}, pages = {46 -- 52}, year = {2015}, language = {en} } @article{SchuetzWeissbeckerHummeletal.1997, author = {Sch{\"u}tz, S. and Weißbecker, B. and Hummel, Hans E. and Sch{\"o}ning, Michael Josef and Riemer, A. and Kordos, P. and L{\"u}th, H.}, title = {Field effect transistor-insect antenna junction}, series = {Naturwissenschaften}, volume = {84}, journal = {Naturwissenschaften}, issn = {1432-1904}, pages = {86 -- 88}, year = {1997}, language = {en} } @article{ThustSchoeningFrohnhoffetal.1996, author = {Thust, Marion and Sch{\"o}ning, Michael Josef and Frohnhoff, S. and Arens-Fischer, R. and Kordos, P. and L{\"u}th, H.}, title = {Porous silicon as a substrate material for potentiometric biosensors}, series = {Measurement Science and Technology}, volume = {7}, journal = {Measurement Science and Technology}, number = {1}, doi = {10.1088/0957-0233/7/1/003}, pages = {26 -- 29}, year = {1996}, language = {en} } @article{WagnerMiyamotoWerneretal.2011, author = {Wagner, Torsten and Miyamoto, K. and Werner, Frederik and Sch{\"o}ning, Michael Josef and Yoshinobu, T.}, title = {Utilising Digital Micro-Mirror Device (DMD) as Scanning Light Source for Light-Addressable Potentiometric Sensors (LAPS)}, volume = {9}, number = {2}, publisher = {American Scientific Publishers}, address = {Stevenson Ranch, Calif.}, doi = {10.1166/sl.2011.1620}, pages = {812 -- 815}, year = {2011}, language = {en} } @article{MartinGonzalezKotliarRiosMartinezetal.2014, author = {Martin-Gonzalez, Anabel and Kotliar, Konstantin and Rios-Martinez, Jorge and Lanzl, Ines and Navab, Nassir}, title = {Mediated-reality magnification for macular degeneration rehabilitation}, series = {Journal of Modern Optics}, volume = {61}, journal = {Journal of Modern Optics}, number = {17}, publisher = {Taylor \& Francis}, address = {London}, issn = {1362-3044}, doi = {10.1080/09500340.2014.936110}, pages = {1400 -- 1408}, year = {2014}, language = {en} } @article{KotliarKharoubiSchmidtTrucksaessetal.2009, author = {Kotliar, Konstantin and Kharoubi, A. and Schmidt-Trucks{\"a}ß, A. and Halle, M. and Lanzl, I.}, title = {Does internal longitudinal microstructure of retinal veins change with age in medically healthy persons?}, series = {Acta Ophthalmologica}, volume = {Vol. 87}, journal = {Acta Ophthalmologica}, number = {Suppl. S244}, publisher = {Wiley}, address = {Weinheim}, issn = {1600-0420 (E-Journal); 1755-3768 (E-Journal); 0001-639X (Print); 1395-3907 (Print); 1755-375X (Print)}, pages = {0}, year = {2009}, language = {en} } @article{WarmerWagnerSchoeningetal.2015, author = {Warmer, Johannes and Wagner, Patrick and Sch{\"o}ning, Michael Josef and Kaul, Peter}, title = {Detection of triacetone triperoxide using temperature cycled metal-oxide semiconductor gas sensors}, series = {Physica status solidi (a)}, volume = {212}, journal = {Physica status solidi (a)}, number = {6}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201431882}, pages = {1289 -- 1298}, year = {2015}, language = {en} } @article{DelleHuckBaeckeretal.2015, author = {Delle, Lotta E. and Huck, Christina and B{\"a}cker, Matthias and M{\"u}ller, Frank and Grandthyll, Samuel and Jacobs, Karin and Lilischkis, Rainer and Vu, Xuan T. and Sch{\"o}ning, Michael Josef and Wagner, Patrick and Thoelen, Roland and Weil, Maryam and Ingebrandt, Sven}, title = {Impedimetric immunosensor for the detection of histamine based on reduced graphene oxide}, series = {Physica status solidi (a)}, volume = {212}, journal = {Physica status solidi (a)}, number = {6}, publisher = {Wiley}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201431863}, pages = {1327 -- 1334}, year = {2015}, language = {en} } @article{SeiblerKleinriddersKueterLuksetal.2007, author = {Seibler, Jost and Kleinridders, Andre and K{\"u}ter-Luks, Birgit and Niehaves, Sandra and Br{\"u}ning, Jens C. and Schwenk, Frieder}, title = {Reversible gene knockdown in mice using a tight, inducible shRNA expression system}, series = {Nucleic Acids Research}, volume = {35}, journal = {Nucleic Acids Research}, number = {7}, issn = {1362-4962}, doi = {10.1093/nar/gkm122}, pages = {e54}, year = {2007}, language = {en} } @article{PlumMaHampeletal.2006, author = {Plum, Leona and Ma, Xiaosong and Hampel, Brigitte and Balthasar, Nina and Coppari, Roberto and M{\"u}nzberg, Heike and Shanabrough, Marya and Burdakov, Denis and Rother, Eva and Janoschek, Ruth and Alber, Jens and Belgardt, Bengt F. and Koch, Linda and Seibler, Jost and Schenk, Frieder and Fekete, Csaba and Suzuki, Akira and Mak, Tak W. and Krone, Wilhelm and Horvath, Tamas L. and Ashcroft, Frances M. and Br{\"u}ning, Jens C.}, title = {Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity}, series = {The Journal of Clinical Investigation (JCI)}, volume = {116}, journal = {The Journal of Clinical Investigation (JCI)}, number = {7}, issn = {1558-8238}, doi = {10.1172/JCI27123}, pages = {1886 -- 1901}, year = {2006}, language = {en} } @article{SeiblerKueterLuksKernetal.2005, author = {Seibler, Jost and K{\"u}ter-Luks, Birgit and Kern, Heidrun and Streu, Sandra and Plum, Leona and Maurer, Jan and K{\"u}hn, Ralf and Br{\"u}ning, Jens C. and Schwenk, Frieder}, title = {Single copy shRNA configuration for ubiquitous gene knockdown in mice}, series = {Nucleic Acids Research}, volume = {33}, journal = {Nucleic Acids Research}, number = {7}, issn = {1362-4962}, doi = {10.1093/nar/gni065}, pages = {e67}, year = {2005}, language = {en} } @article{SeiblerZevnikKueterLuksetal.2003, author = {Seibler, Jost and Zevnik, Branko and K{\"u}ter-Luks, Birgit and Andreas, Susanne and Kern, Heidrun and Hennek, Thomas and Rode, Anja and Heimann, Cornelia and Faust, Nicole and Kauselmann, Gunther and Schoor, Michael and Jaenisch, Rudolf and Rajewsky, Klaus and K{\"u}hn, Ralf and Schwenk, Frieder}, title = {Rapid generation of inducible mouse mutants}, series = {Nucleic Acids Research}, volume = {33}, journal = {Nucleic Acids Research}, number = {4}, issn = {1362-4962}, doi = {10.1093/nar/gng012}, pages = {e12}, year = {2003}, language = {en} } @article{GoetzeBaerWinkelmannetal.2005, author = {Goetze, Sandra and Baer, Alexandra and Winkelmann, Silke and Nehlsen, Kristina and Seibler, Jost and Maass, Karin and Bode, J{\"u}rgen}, title = {Performance of genomic bordering elements at predefined genomic loci}, series = {Molecular and Cellular Biology}, volume = {25}, journal = {Molecular and Cellular Biology}, number = {6}, issn = {1098-5549}, doi = {10.1128/MCB.25.6.2260-2272.2005}, pages = {2260 -- 2272}, year = {2005}, language = {en} } @article{YoshinobuMoritzFingeretal.2006, author = {Yoshinobu, Tatsuo and Moritz, Werner and Finger, Friedhelm and Sch{\"o}ning, Michael Josef}, title = {Application of thin-film amorphous silicon to chemical imaging}, series = {Nanostructured materials and hybrid composites for gas sensors and biomedical applications : symposium held April 18-20, 2006, San Francisco , California, U.S.A.}, journal = {Nanostructured materials and hybrid composites for gas sensors and biomedical applications : symposium held April 18-20, 2006, San Francisco , California, U.S.A.}, number = {Paper 0910-A-20-01}, editor = {Comini, Elisabetta}, isbn = {9781558998711}, pages = {1 -- 10}, year = {2006}, language = {en} }