@article{ManeaLeursOrbanetal.2011, author = {Manea, Marilena and Leurs, Ulrike and Orban, Erika and Baranyai, Zsuzsa and {\"O}hlschl{\"a}ger, Peter and Marquardt, Andreas and Schulcz, Akos and Tejeda, Miguel}, title = {Enhanced Enzymatic Stability and Antitumor Activity of Daunorubicin-GnRH-III Bioconjugates Modified in Position 4}, series = {Bioconjugate Chemistry}, volume = {22}, journal = {Bioconjugate Chemistry}, number = {7}, publisher = {ACS}, address = {Washington, DC}, isbn = {1520-4812}, pages = {1320 -- 1329}, year = {2011}, language = {en} } @article{SpiessWilfriedAlvarezetal.2011, author = {Spiess, Elmar and Wilfried, Reichardt and Alvarez, Gerardo and Gottrup, Marcus and {\"O}hlschl{\"a}ger, Peter}, title = {An Artificial PAP Gene Breaks Self-tolerance and Promotes Tumor Regression in the TRAMP Model for Prostate Carcinoma}, series = {Molecular Therapy}, volume = {20}, journal = {Molecular Therapy}, number = {3}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {1525-0016}, pages = {555 -- 564}, year = {2011}, language = {en} } @article{BaeckerRaueSchusseretal.2012, author = {B{\"a}cker, Matthias and Raue, Markus and Schusser, Sebastian and Jeitner, C. and Breuer, L. and Wagner, P. and Poghossian, Arshak and F{\"o}rster, Arnold and Mang, Thomas and Sch{\"o}ning, Michael Josef}, title = {Microfluidic chip with integrated microvalves based on temperature- and pH-responsive hydrogel thin films}, series = {Physica Status Solidi (a)}, volume = {209}, journal = {Physica Status Solidi (a)}, number = {5}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201100763}, pages = {839 -- 845}, year = {2012}, abstract = {Two types of microvalves based on temperature-responsive poly(N-isopropylacrylamide) (PNIPAAm) and pH-responsive poly(sodium acrylate) (PSA) hydrogel films have been developed and tested. The PNIPAAm and PSA hydrogel films were prepared by means of in situ photopolymerization directly inside the fluidic channel of a microfluidic chip fabricated by combining Si and SU-8 technologies. The swelling/shrinking properties and height changes of the PNIPAAm and PSA films inside the fluidic channel were studied at temperatures of deionized water from 14 to 36 °C and different pH values (pH 3-12) of Titrisol buffer, respectively. Additionally, in separate experiments, the lower critical solution temperature (LCST) of the PNIPAAm hydrogel was investigated by means of a differential scanning calorimetry (DSC) and a surface plasmon resonance (SPR) method. Mass-flow measurements have shown the feasibility of the prepared hydrogel films to work as an on-chip integrated temperature- or pH-responsive microvalve capable to switch the flow channel on/off.}, language = {en} } @article{HuckSchiffelsHerreraetal.2013, author = {Huck, Christina and Schiffels, Johannes and Herrera, Cony N. and Schelden, Maximilian and Selmer, Thorsten and Poghossian, Arshak and Baumann, Marcus and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Metabolic responses of Escherichia coli upon glucose pulses captured by a capacitive field-effect sensor}, series = {Physica Status Solidi (A)}, volume = {210}, journal = {Physica Status Solidi (A)}, number = {5}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0031-8965}, doi = {10.1002/pssa.201200900}, pages = {926 -- 931}, year = {2013}, abstract = {Living cells are complex biological systems transforming metabolites taken up from the surrounding medium. Monitoring the responses of such cells to certain substrate concentrations is a challenging task and offers possibilities to gain insight into the vitality of a community influenced by the growth environment. Cell-based sensors represent a promising platform for monitoring the metabolic activity and thus, the "welfare" of relevant organisms. In the present study, metabolic responses of the model bacterium Escherichia coli in suspension, layered onto a capacitive field-effect structure, were examined to pulses of glucose in the concentration range between 0.05 and 2 mM. It was found that acidification of the surrounding medium takes place immediately after glucose addition and follows Michaelis-Menten kinetic behavior as a function of the glucose concentration. In future, the presented setup can, therefore, be used to study substrate specificities on the enzymatic level and may as well be used to perform investigations of more complex metabolic responses. Conclusions and perspectives highlighting this system are discussed.}, language = {en} } @article{SchiffelsPinkenburgScheldenetal.2013, author = {Schiffels, Johannes and Pinkenburg, Olaf and Schelden, Maximilian and Aboulnaga, El-Hussiny A. A. and Baumann, Marcus and Selmer, Thorsten}, title = {An innovative cloning platform enables large-scale production and maturation of an oxygen-tolerant [NiFe]-hydrogenase from cupriavidus necator in Escherichia coli}, series = {PLOS one. 2013}, journal = {PLOS one. 2013}, publisher = {Public Library of Science}, address = {San Francisco, California}, issn = {1932-6203}, doi = {10.1371/journal.pone.0068812}, year = {2013}, language = {en} } @article{AbulnagaPinkenburgSchiffelsetal.2013, author = {Abulnaga, El-Hussiny and Pinkenburg, Olaf and Schiffels, Johannes and E-Refai, Ahmed and Buckel, Wolfgang and Selmer, Thorsten}, title = {Effect of an Oxygen-Tolerant Bifurcating Butyryl Coenzyme A Dehydrogenase/Electron-Transferring Flavoprotein Complex from Clostridium difficile on Butyrate Production in Escherichia coli}, series = {Journal of bacteriology}, volume = {195}, journal = {Journal of bacteriology}, number = {16}, issn = {1098-5530 [E-Journal]}, pages = {3704 -- 3713}, year = {2013}, language = {en} } @article{KotterHammon1986, author = {Kotter, Michael and Hammon, U.}, title = {Preparation of pellets with well-defined pore structure / U. Hammon ; A. Kotter}, series = {International chemical engineering. 26 (1986), H. 4}, journal = {International chemical engineering. 26 (1986), H. 4}, isbn = {0020-6318}, pages = {563 -- 573}, year = {1986}, language = {en} } @article{ElbersPfefferFrieseletal.1995, author = {Elbers, Gereon and Pfeffer, Hans-Ulrich and Friesel, J{\"u}rgen and Beier, Reinhold}, title = {Air Pollution Monitoring in Street Canyons / Hans-Ulrich Pfeffer, J{\"u}rgen Friesel, Gereon Elbers, Reinhold Beier,}, series = {Transport and air pollution : proceedings ; 3rd international symposium, Palais des Papes, Avignon, France, 6 - 10 June 1994 = Transports et pollution de l'air / [Third International Symposium on Transport and Air Pollution]. Ed. by Robert Joumard. Organizer: French National Institute for Transport and Safety Research}, journal = {Transport and air pollution : proceedings ; 3rd international symposium, Palais des Papes, Avignon, France, 6 - 10 June 1994 = Transports et pollution de l'air / [Third International Symposium on Transport and Air Pollution]. Ed. by Robert Joumard. Organizer: French National Institute for Transport and Safety Research}, publisher = {Elsevier}, address = {Amsterdam}, pages = {IX, 337 S : graph. Darst.}, year = {1995}, language = {en} } @article{ElbersGaebHoffmannetal.2006, author = {Elbers, Gereon and G{\"a}b, Martina and Hoffmann, Katharina and Lobe, Melanie}, title = {NIR-spectroscopic investigation of foliage of ozone-stressed Fagus sylvatica trees / G{\"a}b, Martina ; Hoffmann, Katharina ; Lobe, Melanie ; Metzger, Rut ; Ooyen, Sven van ; Elbers, Gereon ; K{\"o}llner, Barbara}, series = {Journal of Forest Research. 11 (2006), H. 2}, journal = {Journal of Forest Research. 11 (2006), H. 2}, isbn = {1341-6979}, pages = {69 -- 75}, year = {2006}, language = {en} } @article{SchmichEdererEbert1992, author = {Schmich, Peter and Ederer, Hanns J. and Ebert, Klaus H.}, title = {Detection and identification of free radicals in hydrocarbon pyrolysis by an iodine trapping method}, series = {Industrial \& Engineering Chemistry Research. 31 (1992), H. 1}, journal = {Industrial \& Engineering Chemistry Research. 31 (1992), H. 1}, isbn = {1520-5045}, pages = {29 -- 37}, year = {1992}, language = {en} } @article{PrielmeierNagatomoWicketal.1995, author = {Prielmeier, Franz and Nagatomo, Yasushi and Wick, Markus and Frahm, Jens}, title = {Dynamic monitoring of cerebral metabolites during and after transient global ischemia in rats by quantitative proton NMR spectroscopy in vivo / Yasushi Nagatomo, Markus Wick, Franz Prielmeier, Jens Frahm}, series = {NMR in Biomedicine. 8 (1995), H. 6}, journal = {NMR in Biomedicine. 8 (1995), H. 6}, isbn = {1099-1492}, pages = {265 -- 270}, year = {1995}, language = {en} } @article{PrielmeierWickNagatomoetal.1995, author = {Prielmeier, Franz and Wick, Markus and Nagatomo, Yasushi and Frahm, Jens}, title = {Alteration of Intracellular Metabolite Diffusion in Rat Brain In Vivo During Ischemia and Reperfusion / Markus Wick, Yasushi Nagatomo, Franz Prielmeier, Jens Frahm}, series = {Stroke. 26 (1995), H. 10}, journal = {Stroke. 26 (1995), H. 10}, isbn = {0039-2499}, pages = {1930 -- 1934}, year = {1995}, language = {en} } @article{PrielmeierNagatomoFrahm1994, author = {Prielmeier, Franz and Nagatomo, Yasushi and Frahm, Jens}, title = {Cerebral blood oxygenation in rat brain during hypoxic hypoxia. Quantitative MRI of effective transverse relaxation rates}, series = {Magnetic Resonance in Medicine. 31 (1994), H. 6}, journal = {Magnetic Resonance in Medicine. 31 (1994), H. 6}, isbn = {0740-3194}, pages = {678 -- 681}, year = {1994}, language = {en} } @article{MerschenzQuackMootz1988, author = {Merschenz-Quack, Angelika and Mootz, D.}, title = {Structures of sulfuryl halides: SO2F2, SO2CIF and SO2Cl2 / Mootz, D. ; Merschenz-Quack, A.}, series = {Acta crystallographica / Section C, Crystal structure communications. C 44 (1988), H. 5}, journal = {Acta crystallographica / Section C, Crystal structure communications. C 44 (1988), H. 5}, isbn = {0108-2701}, pages = {924 -- 925}, year = {1988}, language = {en} } @article{MerschenzQuackMootz1990, author = {Merschenz-Quack, Angelika and Mootz, D.}, title = {Structure of 5-sulfosalicylic acid pentahydrate}, series = {Acta crystallographica / Section C, Crystal structure communications. C 46 (1990), H. 8}, journal = {Acta crystallographica / Section C, Crystal structure communications. C 46 (1990), H. 8}, isbn = {0108-2701}, pages = {1478 -- 1480}, year = {1990}, language = {en} } @article{Jeromin2001, author = {Jeromin, G{\"u}nter Erich}, title = {Tetrabenzo[a,c,h,j]phenoxazine-18-yl a new stable neutral radical}, series = {Tetrahedron Letters . 42 (2001), H. 10}, journal = {Tetrahedron Letters . 42 (2001), H. 10}, isbn = {0040-4039}, pages = {1863 -- 1865}, year = {2001}, language = {en} } @article{JerominWelsch1995, author = {Jeromin, G{\"u}nter Erich and Welsch, Volker}, title = {Diketene a New Esterification Reagent in the Enzyme-Aided Synthesis of Chiral Alcohols and Chiral Acetoacetic Acid Esters}, series = {Tetrahedron Letters . 36 (1995), H. 37}, journal = {Tetrahedron Letters . 36 (1995), H. 37}, isbn = {0040-4039}, pages = {6663 -- 6664}, year = {1995}, language = {en} } @article{JerominScheidt1991, author = {Jeromin, G{\"u}nter Erich and Scheidt, Annette}, title = {Aliphatic optically active alcohols by enzyme-aided synthesis}, series = {Tetrahedron Letters . 32 (1991), H. 48}, journal = {Tetrahedron Letters . 32 (1991), H. 48}, isbn = {0040-4039}, pages = {7021 -- 7024}, year = {1991}, language = {en} } @article{JerominAlbertz1992, author = {Jeromin, G{\"u}nter Erich and Albertz, Michael}, title = {Optically active \&\#945;-acetoxycarboxylic acids and \&\#945;-hydroxycarboxylic acids by enzyme-aided syntheses}, series = {Journal f{\"u}r Praktische Chemie / Chemiker-Zeitung. 334 (1992), H. 6}, journal = {Journal f{\"u}r Praktische Chemie / Chemiker-Zeitung. 334 (1992), H. 6}, isbn = {1436-9966}, pages = {526 -- 528}, year = {1992}, language = {en} } @article{PrielmeierMerboldtHanickeetal.1993, author = {Prielmeier, Franz and Merboldt, K. D. and Hanicke, W. and Frahm, J.}, title = {Dynamic high-resolution MR imaging of brain deoxygenation during transient anoxia in the anesthetized rat}, series = {Journal of cerebral blood flow and metabolism. 13 (1993), H. 5}, journal = {Journal of cerebral blood flow and metabolism. 13 (1993), H. 5}, isbn = {0271-678X}, pages = {889 -- 894}, year = {1993}, language = {en} }