@inproceedings{BayerHeschelerArtmannetal.2019,
  author    = {Bayer, Robin and Hescheler, J{\"u}rgen and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l},
  title     = {Treating arterial hypertension in a cell culture well},
  series = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH AachenW},
  booktitle = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH AachenW},
  editor    = {Staat, Manfred and Erni, Daniel},
  publisher = {Universit{\"a}t Duisburg-Essen},
  address   = {Duisburg},
  organization    = {MedTech Symposium},
  isbn      = {978-3-940402-22-6},
  doi       = {10.17185/duepublico/48750},
  pages     = {5 -- 6},
  year      = {2019},
  abstract  = {Hypertension describes the pathological increase of blood pressure, which is most commonly associated with the increase of vascular wall stiffness [1]. Referring to the "Deutsche Bluthochdruck Liga" this pathology shows a growing trend in our aging society. In order to find novel pharmacological and probably personalized treatments, we want to present a functional approach to study biomechanical properties of a human aortic vascular model. In this method review we will give an overview of recent studies which were carried out with the CellDrum technology [2] and underline the added value to already existing standard procedures known from the field of physiology. Herein described CellDrum technology is a system to measure functional mechanical properties of cell monolayers and thin tissue constructs in-vitro. Additionally, the CellDrum enables to elucidate the mechanical response of cells to pharmacological drugs, toxins and vasoactive agents. Due to its highly flexible polymer support, cells can also be mechanically stimulated by steady and cyclic biaxial stretching.},
  language  = {en}
}
@article{BayerTemizArtmannDigeletal.2020,
  author    = {Bayer, Robin and Temiz Artmann, Ayseg{\"u}l and Digel, Ilya and Falkenstein, Julia and Artmann, Gerhard and Creutz, Till and Hescheler, J{\"u}rgen},
  title     = {Mechano-pharmacological testing of L-Type Ca²⁺ channel modulators via human vascular celldrum model},
  series = {Cellular Physiology and Biochemistry},
  volume    = {54},
  journal   = {Cellular Physiology and Biochemistry},
  publisher = {Cell Physiol Biochem Press},
  address   = {D{\"u}sseldorf},
  issn      = {1421-9778},
  doi       = {10.33594/000000225},
  pages     = {371 -- 383},
  year      = {2020},
  abstract  = {Background/Aims: This study aimed to establish a precise and well-defined working model, assessing pharmaceutical effects on vascular smooth muscle cell monolayer in-vitro. It describes various analysis techniques to determine the most suitable to measure the biomechanical impact of vasoactive agents by using CellDrum technology. Methods: The so-called CellDrum technology was applied to analyse the biomechanical properties of confluent human aorta muscle cells (haSMC) in monolayer. The cell generated tensions deviations in the range of a few N/m² are evaluated by the CellDrum technology. This study focuses on the dilative and contractive effects of L-type Ca²⁺ channel agonists and antagonists, respectively. We analyzed the effects of Bay K8644, nifedipine and verapamil. Three different measurement modes were developed and applied to determine the most appropriate analysis technique for the study purpose. These three operation modes are called, particular time mode" (PTM), "long term mode" (LTM) and "real-time mode" (RTM). Results: It was possible to quantify the biomechanical response of haSMCs to the addition of vasoactive agents using CellDrum technology. Due to the supplementation of 100nM Bay K8644, the tension increased approximately 10.6\% from initial tension maximum, whereas, the treatment with nifedipine and verapamil caused a significant decrease in cellular tension: 10nM nifedipine decreased the biomechanical stress around 6,5\% and 50nM verapamil by 2,8\%, compared to the initial tension maximum. Additionally, all tested measurement modes provide similar results while focusing on different analysis parameters. Conclusion: The CellDrum technology allows highly sensitive biomechanical stress measurements of cultured haSMC monolayers. The mechanical stress responses evoked by the application of vasoactive calcium channel modulators were quantified functionally (N/m²). All tested operation modes resulted in equal findings, whereas each mode features operation-related data analysis.},
  language  = {en}
}
@article{BeckerWallangArtmannetal.2008,
  author    = {Becker, C. and Wallang, C. and Artmann, Gerhard and Jakse, G.},
  title     = {Mechanotransduction-bioreactor for tissue engineering of a ureter prosthesis},
  series = {International Journal of Artificial Organs, The},
  volume    = {31},
  journal   = {International Journal of Artificial Organs, The},
  number    = {7},
  issn      = {0391-3988},
  pages     = {583 -- 583},
  year      = {2008},
  language  = {en}
}
@article{BeerStreunHombachetal.2010,
  author    = {Beer, S. and Streun, M. and Hombach, T. and Buehler, J. and Jahnke, S. and Khodaverdi, M. and Larue, H. and Minwuyelet, S. and Parl, C. and Roeb, G. and Schurr, U. and Ziemons, Karl},
  title     = {Design and initial performance of PlanTIS: a high-resolution positron emission tomograph for plants},
  series = {Physics in Medicine and Biology},
  volume    = {55},
  journal   = {Physics in Medicine and Biology},
  number    = {3},
  publisher = {IOP},
  address   = {Bristol},
  issn      = {1361-6560},
  doi       = {10.1088/0031-9155/55/3/006},
  pages     = {635 -- 646},
  year      = {2010},
  abstract  = {Positron emitters such as 11C, 13N and 18F and their labelled compounds are widely used in clinical diagnosis and animal studies, but can also be used to study metabolic and physiological functions in plants dynamically and in vivo. A very particular tracer molecule is 11CO2 since it can be applied to a leaf as a gas. We have developed a Plant Tomographic Imaging System (PlanTIS), a high-resolution PET scanner for plant studies. Detectors, front-end electronics and data acquisition architecture of the scanner are based on the ClearPET™ system. The detectors consist of LSO and LuYAP crystals in phoswich configuration which are coupled to position-sensitive photomultiplier tubes. Signals are continuously sampled by free running ADCs, and data are stored in a list mode format. The detectors are arranged in a horizontal plane to allow the plants to be measured in the natural upright position. Two groups of four detector modules stand face-to-face and rotate around the field-of-view. This special system geometry requires dedicated image reconstruction and normalization procedures. We present the initial performance of the detector system and first phantom and plant measurements.},
  language  = {en}
}
@article{BegingLeinhosJablonskietal.2015,
  author    = {Beging, Stefan and Leinhos, Marcel and Jablonski, Melanie and Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {Studying the spatially resolved immobilisation of enzymes on a capacitive field-effect structure by means of nano-spotting},
  series = {Physica status solidi (a)},
  volume    = {212},
  journal   = {Physica status solidi (a)},
  number    = {6},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201431891},
  pages     = {1353 -- 1358},
  year      = {2015},
  language  = {en}
}
@article{BegingMlynekHataihimakuletal.2010,
  author    = {Beging, Stefan and Mlynek, Daniela and Hataihimakul, Sudkanung and Poghossian, Arshak and Baldsiefen, Gerhard and Busch, Heinz and Laube, Norbert and Kleinen, Lisa and Sch{\"o}ning, Michael Josef},
  title     = {Field-effect calcium sensor for the determination of the risk of urinary stone formation},
  series = {Sensors and Actuators B: Chemical. 144 (2010), H. 2},
  journal   = {Sensors and Actuators B: Chemical. 144 (2010), H. 2},
  pages     = {374 -- 379},
  year      = {2010},
  language  = {en}
}
@inproceedings{BegingPoghossianMlyneketal.2010,
  author    = {Beging, Stefan and Poghossian, Arshak and Mlynek, D. and Hataihimakul, S. and Pedraza, A. and Dhawan, S. and Laube, N. and Kleinen, L. and Baldsiefen, G. and Busch, H. and Sch{\"o}ning, Michael Josef},
  title     = {Ion-selective sensors for the determination of the risk of urinary stone formation},
  series = {Micro- and Nanosystems in biochemical diagnosis : Principles and applications},
  booktitle = {Micro- and Nanosystems in biochemical diagnosis : Principles and applications},
  address   = {Warsaw},
  pages     = {74 -- 80},
  year      = {2010},
  language  = {en}
}
@article{BegingPoghossianSchoeningetal.2008,
  author    = {Beging, Stefan and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Hataihimakul, Sudkanung and Busch, H. and Baldsiefen, G. and Laube, N. and Kleinen, L. and Hosseiny, R.},
  title     = {Feldeffektbasierender Ca2+-sensitiver Sensor f{\"u}r den Einsatz im Nativurin zur Bestimmung des Harnsteinbildungsrisikos},
  series = {Sensoren und Messsysteme 2008 : 14. Fachtagung Ludwigsburg, 11. und 12. M{\"a}rz 2008 / VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik},
  journal   = {Sensoren und Messsysteme 2008 : 14. Fachtagung Ludwigsburg, 11. und 12. M{\"a}rz 2008 / VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik},
  publisher = {VDI-Verl.},
  address   = {D{\"u}sseldorf},
  isbn      = {978-3-18-092011-5},
  pages     = {775 -- 782},
  year      = {2008},
  language  = {de}
}
@phdthesis{Behbahani2011,
  author    = {Behbahani, Mehdi},
  title     = {Modeling and Simulation of Shear-Dependent Platelet Reactions in Blood Vessels and Blood-Contacting Medical Devices},
  publisher = {Verlag Dr. Hut},
  address   = {M{\"u}nchen},
  isbn      = {978-3-8439-0134-5},
  year      = {2011},
  language  = {en}
}
@article{BehbahaniBehrAroraetal.2006,
  author    = {Behbahani, Mehdi and Behr, M. and Arora, D. and Coronado, O. and Pasquali, M.},
  title     = {CFD Analysis of MicroMed Debakey Pump and Hemolysis Prediction / Behbahani, M. ; Behr, M. ; Arora, D. ; Coronado, O. ; Pasquali, M.},
  series = {Artificial Organs. 30 (2006), H. 11},
  journal   = {Artificial Organs. 30 (2006), H. 11},
  isbn      = {1525-1594},
  pages     = {A45 -- A46},
  year      = {2006},
  language  = {en}
}
@article{BehbahaniBehrBischofetal.2007,
  author    = {Behbahani, Mehdi and Behr, M. and Bischof, F. and Wolf, G. E.},
  title     = {Kranken Herzen helfen - Ingenieure und Informatiker entwickeln gemeinsam eine Miniaturblutpumpe / Behbahani, M. ; Behr, M. ; Bischof, F. ; Wolf, G. E.},
  series = {RWTH-Themen (2007)},
  journal   = {RWTH-Themen (2007)},
  isbn      = {0179-079X},
  pages     = {44 -- 46},
  year      = {2007},
  language  = {de}
}
@article{BehbahaniBehrHormesetal.2009,
  author    = {Behbahani, Mehdi and Behr, M. and Hormes, M. and Steinseifer, U. and Arora, D. and Coronado, O. and Pasquali, M.},
  title     = {A Review of Computational Fluid Dynamics Analysis of Blood Pumps},
  series = {European Journal of Applied Mathematics. 20 (2009), H. 4},
  journal   = {European Journal of Applied Mathematics. 20 (2009), H. 4},
  publisher = {Cambridge Univ. Press},
  address   = {Cambridge},
  pages     = {363 -- 397},
  year      = {2009},
  language  = {en}
}
@article{BehbahaniBehrNicolaietal.2008,
  author    = {Behbahani, Mehdi and Behr, Marek and Nicolai, Mike and Probst, Markus},
  title     = {Towards Shape Optimization for Ventricular Assist Devices Using Parallel Stabilized FEM},
  series = {NIC Symposium 2008 : symposium, 20 - 21 February 2008, Forschungszentrum J{\"u}lich ; proceedings / organized by John von Neumann Institute for Computing. Ed. by Gernot M{\"u}nster; Dietrich Wolf; Manfred Kremer (ed.)},
  journal   = {NIC Symposium 2008 : symposium, 20 - 21 February 2008, Forschungszentrum J{\"u}lich ; proceedings / organized by John von Neumann Institute for Computing. Ed. by Gernot M{\"u}nster; Dietrich Wolf; Manfred Kremer (ed.)},
  publisher = {Forschungszentrum},
  address   = {J{\"u}lich},
  isbn      = {978-3-9810843-5-1},
  pages     = {325 -- 332},
  year      = {2008},
  language  = {en}
}
@article{BehbahaniFinocchiaroHeinkeetal.2009,
  author    = {Behbahani, Mehdi and Finocchiaro, Thomas and Heinke, Stefanie and Leßmann, Marc},
  title     = {Methods of design, simulation, and control for the development of new VAD/TAH concepts = Methoden zur Konstruktion, Simulation und Regelung f{\"u}r die Entwicklung von neuen VAD/TAH-Konzepten / Finocchiaro, Thomas ; Heinke, Stefanie ; Behbahani, Mehdi ; Leßma},
  series = {Biomedizinische Technik / Biomedical Engineering. 54 (2009), H. 5},
  journal   = {Biomedizinische Technik / Biomedical Engineering. 54 (2009), H. 5},
  isbn      = {0013-5585},
  pages     = {269 -- 281},
  year      = {2009},
  language  = {en}
}
@article{BehbahaniMaiBergmannetal.2010,
  author    = {Behbahani, Mehdi and Mai, A. and Bergmann, B. and Waluga, C. and Behr, M. and Tran, L. and Vonderstein, K. and Mottaghy, K.},
  title     = {Modeling and Numerical Simulation of Blood Damage},
  year      = {2010},
  language  = {en}
}
@article{BehbahaniMaiWalugaetal.2010,
  author    = {Behbahani, Mehdi and Mai, A. and Waluga, C. and Bergmann, B. and Tran, L. and Vonderstein, K. and Behr, M. and Mottaghy, K.},
  title     = {Numerical Modeling of Flow-Related Thrombus Formation under Physiological and Non-Physiological Flow Conditions},
  series = {Acta Physiologica},
  volume    = {198},
  journal   = {Acta Physiologica},
  number    = {Supplement 677},
  isbn      = {1748-1716},
  pages     = {185},
  year      = {2010},
  language  = {en}
}
@article{BehbahaniNamWalugaetal.2010,
  author    = {Behbahani, Mehdi and Nam, J. and Waluga, C. and Behr, M. and Pasquali, M. and Mottaghy, K.},
  title     = {Modeling and Numerical Analysis of Platelet Activation, Adhesion and Aggregation in Artificial Organs},
  doi       = {10.1097/01.mat.0000369377.65122.a3},
  year      = {2010},
  language  = {en}
}
@article{BehbahaniNicolai2006,
  author    = {Behbahani, Mehdi and Nicolai, M.},
  title     = {Interaktive Exploration von Blutstr{\"o}mungsprozessen in Herzpumpen},
  series = {VRCA-Jahresbericht 2005/2006},
  journal   = {VRCA-Jahresbericht 2005/2006},
  publisher = {Virtual Reality Center},
  address   = {Aachen},
  pages     = {88 -- 90},
  year      = {2006},
  language  = {de}
}
@article{BehbahaniNicolaiProbstetal.2007,
  author    = {Behbahani, Mehdi and Nicolai, M. and Probst, M. and Behr, M.},
  title     = {Simulation of Blood Flow in a Ventricular Assist Device},
  series = {inSIDE. 5 (2007), H. 1},
  journal   = {inSIDE. 5 (2007), H. 1},
  pages     = {28 -- 31},
  year      = {2007},
  language  = {en}
}
@article{BehbahaniProbstMaietal.2010,
  author    = {Behbahani, Mehdi and Probst, M. and Mai, A. and Behr, M. and Tran, L. and Vonderstein, K. and Mottaghy, K.},
  title     = {Numerical Prediction of Blood Damage in Biomedical Devices},
  year      = {2010},
  language  = {en}
}