@article{BronderPoghossianSchejaetal.2015, author = {Bronder, Thomas and Poghossian, Arshak and Scheja, Sabrina and Wu, Chunsheng and Keusgen, Michael and Mewes, Dieter and Sch{\"o}ning, Michael Josef}, title = {DNA Immobilization and Hybridization Detection by the Intrinsic Molecular Charge Using Capacitive Field-Effect Sensors Modified with a Charged Weak Polyelectrolyte Layer}, series = {Applied Materials \& Interfaces}, volume = {36}, journal = {Applied Materials \& Interfaces}, number = {7}, publisher = {American Chemical Society}, address = {Washington, DC}, doi = {10.1021/acsami.5b05146}, pages = {20068 -- 20075}, year = {2015}, abstract = {Miniaturized setup, compatibility with advanced micro- and nanotechnologies, and ability to detect biomolecules by their intrinsic molecular charge favor the semiconductor field-effect platform as one of the most attractive approaches for the development of label-free DNA chips. In this work, a capacitive field-effect EIS (electrolyte-insulator-semiconductor) sensor covered with a layer-by-layer prepared, positively charged weak polyelectrolyte layer of PAH (poly(allylamine hydrochloride)) was used for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization. The negatively charged probe single-stranded DNA (ssDNA) molecules were electrostatically adsorbed onto the positively charged PAH layer, resulting in a preferentially flat orientation of the ssDNA molecules within the Debye length, thus yielding a reduced charge-screening effect and a higher sensor signal. Each sensor-surface modification step (PAH adsorption, probe ssDNA immobilization, hybridization with complementary target DNA (cDNA), reducing an unspecific adsorption by a blocking agent, incubation with noncomplementary DNA (ncDNA) solution) was monitored by means of capacitance-voltage and constant-capacitance measurements. In addition, the surface morphology of the PAH layer was studied by atomic force microscopy and contact-angle measurements. High hybridization signals of 34 and 43 mV were recorded in low-ionic strength solutions of 10 and 1 mM, respectively. In contrast, a small signal of 4 mV was recorded in the case of unspecific adsorption of fully mismatched ncDNA. The density of probe ssDNA and dsDNA molecules as well as the hybridization efficiency was estimated using the experimentally measured DNA immobilization and hybridization signals and a simplified double-layer capacitor model. The results of field-effect experiments were supported by fluorescence measurements, verifying the DNA-immobilization and hybridization event.}, language = {en} } @article{CehreliAkpinarTemizArtmannetal.2015, author = {Cehreli, Ruksan and Akpinar, Hale and Temiz Artmann, Ayseg{\"u}l and Sagol, Ozgul}, title = {Effects of Glutamine and Omega-3 Fatty Acids on Erythrocyte Deformability and Oxidative Damage in Rat Model of Enterocolitis}, series = {Gastroenterology Research}, volume = {8}, journal = {Gastroenterology Research}, number = {5}, issn = {1918-2813}, doi = {10.14740/gr683w}, pages = {265 -- 273}, year = {2015}, language = {en} } @article{ChenClauserMarquartetal.2015, author = {Chen, Tao and Clauser, Christoph and Marquart, Gabriele and Willbrand, Karen and Mottaghy, Darius}, title = {A new upscaling method for fractured porous media}, series = {Advances in Water Resources}, volume = {80}, journal = {Advances in Water Resources}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0309-1708}, doi = {10.1016/j.advwatres.2015.03.009}, pages = {60 -- 68}, year = {2015}, language = {en} } @article{DantismTakenagaWagneretal.2015, author = {Dantism, S. and Takenaga, S. and Wagner, P. and Wagner, Torsten and Sch{\"o}ning, Michael Josef}, title = {Light-addressable Potentiometric Sensor (LAPS) Combined with Multi-chamber Structures to Investigate the Metabolic Activity of Cells}, series = {Procedia Engineering}, volume = {120}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2015.08.647}, pages = {384 -- 387}, year = {2015}, abstract = {LAPS are field-effect-based potentiometric sensors which are able to monitor analyte concentrations in a spatially resolved manner. Hence, a LAPS sensor system is a powerful device to record chemical imaging of the concentration of chemical species in an aqueous solution, chemical reactions, or the growth of cell colonies on the sensor surface, to record chemical images. In this work, multi-chamber 3D-printed structures made out of polymer (PP-ABS) were combined with LAPS chips to analyse differentially and simultaneously the metabolic activity of Escherichia coli K12 and Chinese hamster ovary (CHO) cells, and the responds of those cells to the addition of glucose solution.}, language = {en} } @article{DelleHuckBaeckeretal.2015, author = {Delle, Lotta E. and Huck, Christina and B{\"a}cker, Matthias and M{\"u}ller, Frank and Grandthyll, Samuel and Jacobs, Karin and Lilischkis, Rainer and Vu, Xuan T. and Sch{\"o}ning, Michael Josef and Wagner, Patrick and Thoelen, Roland and Weil, Maryam and Ingebrandt, Sven}, title = {Impedimetric immunosensor for the detection of histamine based on reduced graphene oxide}, series = {Physica status solidi (a)}, volume = {212}, journal = {Physica status solidi (a)}, number = {6}, publisher = {Wiley}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201431863}, pages = {1327 -- 1334}, year = {2015}, language = {en} } @article{DiktaKuehlheimMendoncaetal.2015, author = {Dikta, Gerhard and K{\"u}hlheim, Ren{\´e} and Mendonca, Jorge and Una-Alcarez, Jacobo de}, title = {Asymptotic representation of presmoothed Kaplan-Meier integrals with covariates in a semiparametric censorship model}, series = {Journal of Statistical Planning and Inference}, volume = {Vol. 171}, journal = {Journal of Statistical Planning and Inference}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0378-3758}, doi = {10.1016/j.jspi.2015.12.001}, pages = {10 -- 37}, year = {2015}, language = {en} } @article{DuongNguyenStaat2015, author = {Duong, Minh Tuan and Nguyen, Nhu Huynh and Staat, Manfred}, title = {Physical response of hyperelastic models for composite materials and soft tissues}, series = {Asia pacific journal on computational engineering}, volume = {2}, journal = {Asia pacific journal on computational engineering}, number = {3 (December 2015)}, issn = {2196-1166}, doi = {10.1186/s40540-015-0015-x}, pages = {1 -- 18}, year = {2015}, language = {en} } @article{DuongNguyenTranetal.2015, author = {Duong, Minh Tuan and Nguyen, Nhu Huynh and Tran, Thanh Ngoc and Tolba, R. H. and Staat, Manfred}, title = {Influence of refrigerated storage on tensile mechanical properties of porcine liver and spleen}, series = {International biomechanics}, volume = {Vol. 2}, journal = {International biomechanics}, number = {Iss. 1}, publisher = {Taylor \& Francis}, address = {London}, issn = {2333-5432}, doi = {10.1080/23335432.2015.1049295}, pages = {79 -- 88}, year = {2015}, language = {en} } @article{DoeringRegerKuhnhenneetal.2015, author = {D{\"o}ring, Bernd and Reger, Vitali and Kuhnhenne, Markus and Feldmann, Markus and Kesti, Jyrki and Lawson, Mark and Botti, Andrea}, title = {Steel solutions for enabling zero-energy buildings}, series = {Steel Construction - Design and Research}, volume = {8}, journal = {Steel Construction - Design and Research}, number = {3}, publisher = {Ernst \& Sohn}, address = {Berlin}, issn = {1867-0539}, doi = {10.1002/stco.201510029}, pages = {194 -- 200}, year = {2015}, language = {en} } @article{FateriGebhardt2015, author = {Fateri, Miranda and Gebhardt, Andreas}, title = {Selective Laser Melting of Soda-Lime Glass Powder}, series = {International Journal of Applied Ceramic Technology}, volume = {12}, journal = {International Journal of Applied Ceramic Technology}, number = {1}, publisher = {Wiley-Blackwell}, address = {Oxford}, issn = {1744-7402}, doi = {10.1111/ijac.12338}, pages = {53 -- 61}, year = {2015}, language = {en} } @article{FateriGebhardt2015, author = {Fateri, Miranda and Gebhardt, Andreas}, title = {Process Parameters Development of Selective Laser Melting of Lunar Regolith for On-Site Manufacturing Applications}, series = {International Journal of Applied Ceramic Technology}, volume = {12}, journal = {International Journal of Applied Ceramic Technology}, number = {1}, publisher = {Wiley-Blackwell}, address = {Oxford}, isbn = {1744-7402}, doi = {10.1111/ijac.12326}, pages = {46 -- 52}, year = {2015}, language = {en} } @article{FateriGebhardt2015, author = {Fateri, Miranda and Gebhardt, Andreas}, title = {Additive manufactured mechanical disentanglement lock}, series = {RTejournal - Forum f{\"u}r Rapid Technologie}, volume = {12}, journal = {RTejournal - Forum f{\"u}r Rapid Technologie}, publisher = {Fachhochschule Aachen}, address = {Aachen}, issn = {1614-0923}, url = {http://nbn-resolving.de/urn:nbn:de:0009-2-42147}, year = {2015}, language = {en} } @article{FeichtingerEilmannBuchmannetal.2015, author = {Feichtinger, Linda M. and Eilmann, Britta and Buchmann, Nina and Rigling, Andreas}, title = {Trait-specific responses of Scots pine to irrigation on a short vs long time scale}, series = {Tree Physiology}, volume = {35}, journal = {Tree Physiology}, number = {00}, publisher = {Heron}, address = {Victoria, BC}, issn = {1758-4469 (Online)}, doi = {10.1093/treephys/tpu114}, pages = {1 -- 12}, year = {2015}, language = {en} } @article{FischerSelverGezeretal.2015, author = {Fischer, Felix and Selver, M. Alper and Gezer, Sinem and Dicle, Oguz and Hillen, Walter}, title = {Systematic Parameterization, Storage, and Representation of Volumetric DICOM Data}, series = {Journal of Medical and Biological Engineering}, volume = {35}, journal = {Journal of Medical and Biological Engineering}, number = {6}, publisher = {Springer}, address = {Berlin}, issn = {2199-4757}, doi = {10.1007/s40846-015-0097-5}, pages = {709 -- 723}, year = {2015}, language = {en} } @article{FrotscherKochStaat2015, author = {Frotscher, Ralf and Koch, Jan-Peter and Staat, Manfred}, title = {Computational investigation of drug action on human-induced stem cell derived cardiomyocytes}, series = {Journal of biomechanical engineering}, volume = {Vol. 137}, journal = {Journal of biomechanical engineering}, number = {iss. 7}, publisher = {ASME}, address = {New York}, issn = {1528-8951 (E-Journal); 0148-0731 (Print)}, doi = {10.1115/1.4030173}, pages = {071002-1 -- 071002-7}, year = {2015}, language = {en} } @article{GeierBialonskiElgeretal.2015, author = {Geier, Christian and Bialonski, Stephan and Elger, Christian E. and Lehnertz, Klaus}, title = {How important is the seizure onset zone for seizure dynamics?}, series = {Seizure}, volume = {25}, journal = {Seizure}, issn = {1059-1311}, doi = {10.1016/j.seizure.2014.10.013}, pages = {160 -- 166}, year = {2015}, language = {en} } @article{GeierLehnertzBialonski2015, author = {Geier, Christian and Lehnertz, Klaus and Bialonski, Stephan}, title = {Time-dependent degree-degree correlations in epileptic brain networks: from assortative to dissortative mixing}, series = {Frontiers in Human Neuroscience}, journal = {Frontiers in Human Neuroscience}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1662-5161}, doi = {10.3389/fnhum.2015.00462}, year = {2015}, language = {en} } @article{GrundmannDachwaldGrimmetal.2015, author = {Grundmann, Jan Thimo and Dachwald, Bernd and Grimm, Christian D. and Kahle, Ralph and Koch, Aaron Dexter and Krause, Christian and Lange, Caroline and Quantius, Dominik and Ulamec, Stephan}, title = {Spacecraft for Hypervelocity Impact Research - An Overview of Capabilities, Constraints and the Challenges of Getting There}, series = {Procedia Engineering}, volume = {Vol. 103}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2015.04.021}, pages = {151 -- 158}, year = {2015}, language = {en} } @article{HagerHentschkeHojdisetal.2015, author = {Hager, Jonathan and Hentschke, Reinhard and Hojdis, Nils and Karimi-Varzaneh, Hossein Ali}, title = {Computer Simulation of Particle-Particle Interaction in a Model Polymer Nanocomposite}, series = {Macromolecules}, volume = {48}, journal = {Macromolecules}, number = {24}, issn = {1520-5835}, doi = {10.1021/acs.macromol.5b01864}, pages = {9039 -- 9049}, year = {2015}, language = {en} } @article{HajAyedKustererFunkeetal.2015, author = {Haj Ayed, A. and Kusterer, K. and Funke, Harald and Keinz, Jan and Striegan, Constantin and Bohn, D.}, title = {Experimental and numerical investigations of the dry-low-NOx hydrogen micromix combustion chamber of an industrial gas turbine}, series = {Propulsion and power research}, volume = {Vol. 4}, journal = {Propulsion and power research}, number = {Iss. 3}, issn = {2212-540X}, doi = {10.1016/j.jppr.2015.07.005}, pages = {123 -- 131}, year = {2015}, language = {en} }