@article{PoghossianKatzSchoening2015,
  author    = {Poghossian, Arshak and Katz, Evgeny and Sch{\"o}ning, Michael Josef},
  title     = {Enzyme logic AND-Reset and OR-Reset gates based on a field-effect electronic transducer modified with multi-enzyme membrane},
  series = {Chemical Communications},
  volume    = {51},
  journal   = {Chemical Communications},
  publisher = {Royal Society of Chemistry (RSC)},
  address   = {Cambridge},
  doi       = {10.1039/C5CC01362C},
  pages     = {6564 -- 6567},
  year      = {2015},
  abstract  = {Capacitive field-effect sensors modified with a multi-enzyme membrane have been applied for an electronic transduction of biochemical signals processed by enzyme-based AND-Reset and OR-Reset logic gates. The local pH change at the sensor surface induced by the enzymatic reaction was used for the activation of the Reset function for the first time.},
  language  = {en}
}
@article{PoettgenEdererAltherretal.2015,
  author    = {P{\"o}ttgen, Philipp and Ederer, Thorsten and Altherr, Lena and Lorenz, Ulf and Pelz, Peter F.},
  title     = {Examination and optimization of a heating circuit for energy-efficient buildings},
  series = {Energy Technology},
  volume    = {4},
  journal   = {Energy Technology},
  number    = {1},
  publisher = {WILEY-VCH Verlag},
  address   = {Weinheim},
  isbn      = {2194-4296},
  doi       = {10.1002/ente.201500252},
  pages     = {136 -- 144},
  year      = {2015},
  abstract  = {The conference center darmstadtium in Darmstadt is a prominent example of energy efficient buildings. Its heating system consists of different source and consumer circuits connected by a Zortstr{\"o}m reservoir. Our goal was to reduce the energy costs of the system as much as possible. Therefore, we analyzed its supply circuits. The first step towards optimization is a complete examination of the system: 1) Compilation of an object list for the system, 2) collection of the characteristic curves of the components, and 3) measurement of the load profiles of the heat and volume-flow demand. Instead of modifying the system manually and testing the solution by simulation, the second step was the creation of a global optimization program. The objective was to minimize the total energy costs for one year. We compare two different topologies and show opportunities for significant savings.},
  language  = {en}
}
@article{PoettgenEdererAltherretal.2015,
  author    = {P{\"o}ttgen, Philipp and Ederer, Thorsten and Altherr, Lena and Pelz, Peter F.},
  title     = {Developing a control strategy for booster stations under uncertain load},
  series = {Applied Mechanics and Materials},
  volume    = {807},
  journal   = {Applied Mechanics and Materials},
  number    = {807},
  publisher = {Trans Tech Publications},
  address   = {B{\"a}ch},
  isbn      = {1662-7482},
  doi       = {10.4028/www.scientific.net/AMM.807.241},
  pages     = {241 -- 246},
  year      = {2015},
  abstract  = {Booster stations can fulfill a varying pressure demand with high energy-efficiency, because individual pumps can be deactivated at smaller loads. Although this is a seemingly simple approach, it is not easy to decide precisely when to activate or deactivate pumps. Contemporary activation controls derive the switching points from the current volume flow through the system. However, it is not measured directly for various reasons. Instead, the controller estimates the flow based on other system properties. This causes further uncertainty for the switching decision. In this paper, we present a method to find a robust, yet energy-efficient activation strategy.},
  language  = {en}
}
@article{ReisertGeisslerWeileretal.2015,
  author    = {Reisert, Steffen and Geissler, H. and Weiler, C. and Wagner, P. and Sch{\"o}ning, Michael Josef},
  title     = {Multiple sensor-type system for monitoring the microbicidal effectiveness of aseptic sterilisation processes},
  series = {Food control},
  volume    = {47},
  journal   = {Food control},
  issn      = {1873-7129 (E-Journal); 0956-7135 (Print)},
  doi       = {10.1016/j.foodcont.2014.07.063},
  pages     = {615 -- 622},
  year      = {2015},
  abstract  = {The present work describes a novel multiple sensor-type system for the real-time analysis of aseptic sterilisation processes employing gaseous hydrogen peroxide (H2O2) as a sterilant. The inactivation kinetics of Bacillus atrophaeus by gaseous H2O2 have been investigated by means of a methodical calibration experiment, taking into account the process variables H2O2 concentration, humidity and gas temperature. It has been found that the microbicidal effectiveness at H2O2 concentrations above 2\% v/v is largely determined by the concentration itself, while at lower H2O2 concentrations, the gas temperature and humidity play a leading role. Furthermore, the responses of different types of gas sensors towards the influencing factors of the sterilisation process have been analysed within the same experiment. Based on a correlation established between the inactivation kinetics and the sensor responses, a calorimetric H2O2 sensor and a metal-oxide semiconductor (MOX) sensor have been identified as possible candidates for monitoring the microbicidal effectiveness of aseptic sterilisation processes employing gaseous H2O2. Therefore, two linear models that describe the relationship between sensor response and microbicidal effectiveness have been proposed.},
  language  = {en}
}
@article{ScheerKapelyukhRodeetal.2015,
  author    = {Scheer, Nico and Kapelyukh, Yury and Rode, Anja and Oswald, Stefan and Busch, Diana and Mclaughlin, Lesley A. and Lin, De and Henderson, Colin J. and Wolf, C. Roland},
  title     = {Defining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse Model},
  series = {Drug Metabolism and Disposition},
  volume    = {43},
  journal   = {Drug Metabolism and Disposition},
  number    = {11},
  publisher = {ASPET},
  address   = {Bethesda},
  issn      = {1521-009x},
  doi       = {10.1124/dmd.115.065656},
  pages     = {1679 -- 1690},
  year      = {2015},
  language  = {en}
}
@article{SchiffelsSelmer2015,
  author    = {Schiffels, Johannes and Selmer, Thorsten},
  title     = {A flexible toolbox to study protein-assisted metalloenzyme assembly in vitro},
  series = {Biotechnology and Bioengineering},
  volume    = {112},
  journal   = {Biotechnology and Bioengineering},
  number    = {11},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1097-0290},
  doi       = {10.1002/bit.25658},
  pages     = {2360 -- 2372},
  year      = {2015},
  language  = {en}
}
@article{SchifferFerreinLakemeyer2015,
  author    = {Schiffer, Stefan and Ferrein, Alexander and Lakemeyer, Gerhard},
  title     = {Abstracting Away Low-Level Details in Service Robotics with Fuzzy Fluents},
  series = {Model-Driven Knowledge Engineering for Improved Software Modularity in Robotics and Automation. Workshop at European Robotics Forum 2015 Vienna, Austria, March 11-13, 2015.},
  journal   = {Model-Driven Knowledge Engineering for Improved Software Modularity in Robotics and Automation. Workshop at European Robotics Forum 2015 Vienna, Austria, March 11-13, 2015.},
  pages     = {1 -- 4},
  year      = {2015},
  language  = {en}
}
@article{SchneiderTran2015,
  author    = {Schneider, Felix and Tran, Duc Hung},
  title     = {On the relation between the fair value option and bid-ask spreads: descriptive evidence on the recognition of credit risk changes under IFRS},
  series = {Journal of Business Economics},
  volume    = {85},
  journal   = {Journal of Business Economics},
  number    = {9},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1861-8928},
  doi       = {10.1007/s11573-015-0776-2},
  pages     = {1049 -- 1081},
  year      = {2015},
  language  = {en}
}
@article{SchreiberBarkschatKraftetal.2015,
  author    = {Schreiber, Marc and Barkschat, Kai and Kraft, Bodo and Z{\"u}ndorf, Albert},
  title     = {Quick Pad Tagger : An Efficient Graphical User Interface for Building Annotated Corpora with Multiple Annotation Layers},
  series = {Computer Science \& Information Technology (CS \& IT)},
  volume    = {5},
  journal   = {Computer Science \& Information Technology (CS \& IT)},
  number    = {4},
  publisher = {Academy \& Industry Research Collaboration Center (AIRCC)},
  isbn      = {978-1-921987-32-8},
  issn      = {2231 - 5403},
  doi       = {10.5121/csit.2015.50413},
  pages     = {131 -- 143},
  year      = {2015},
  language  = {en}
}
@article{SchusserKrischerMolinetal.2015,
  author    = {Schusser, Sebastian and Krischer, M. and Molin, D. G. M. and Akker, N. M. S. van den and B{\"a}cker, Matthias and Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {Sensor System for in-situ and Real-time Monitoring of Polymer (bio) degradation},
  series = {Procedia Engineering},
  volume    = {120},
  journal   = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2015.08.815},
  pages     = {948 -- 951},
  year      = {2015},
  abstract  = {A sensor system for investigating (bio)degradationprocesses of polymers is presented. The system utilizes semiconductor field-effect sensors and is capable of monitoring the degradation process in-situ and in real-time. The degradation of the polymer poly(d,l-lactic acid) is exemplarily monitored in solutions with different pH value, pH-buffer solution containing the model enzyme lipase from Rhizomucormiehei and cell-culture medium containing supernatants from stimulated and non-stimulated THP-1-derived macrophages mimicking activation of the immune system.},
  language  = {en}
}
@article{SchusserKrischerBaeckeretal.2015,
  author    = {Schusser, Sebastian and Krischer, Maximillian and B{\"a}cker, Matthias and Poghossian, Arshak and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Monitoring of the Enzymatically Catalyzed Degradation of Biodegradable Polymers by Means of Capacitive Field-Effect Sensors},
  series = {Analytical Chemistry},
  volume    = {87},
  journal   = {Analytical Chemistry},
  number    = {13},
  publisher = {ACS Publications},
  address   = {Washington, DC},
  issn      = {1520-6882},
  doi       = {10.1021/acs.analchem.5b00617},
  pages     = {6607 -- 6613},
  year      = {2015},
  abstract  = {Designing novel or optimizing existing biodegradable polymers for biomedical applications requires numerous tests on the effect of substances on the degradation process. In the present work, polymer-modified electrolyte-insulator-semiconductor (PMEIS) sensors have been applied for monitoring an enzymatically catalyzed degradation of polymers for the first time. The thin films of biodegradable polymer poly(d,l-lactic acid) and enzyme lipase were used as a model system. During degradation, the sensors were read-out by means of impedance spectroscopy. In order to interpret the data obtained from impedance measurements, an electrical equivalent circuit model was developed. In addition, morphological investigations of the polymer surface have been performed by means of in situ atomic force microscopy. The sensor signal change, which reflects the progress of degradation, indicates an accelerated degradation in the presence of the enzyme compared to hydrolysis in neutral pH buffer media. The degradation rate increases with increasing enzyme concentration. The obtained results demonstrate the potential of PMEIS sensors as a very promising tool for in situ and real-time monitoring of degradation of polymers.},
  language  = {en}
}
@article{SchusserPoghossianBaeckeretal.2015,
  author    = {Schusser, Sebastian and Poghossian, Arshak and B{\"a}cker, Matthias and Krischer, M. and Leinhos, Marcel and Wagner, P. and Sch{\"o}ning, Michael Josef},
  title     = {An application of field-effect sensors for in-situ monitoring of degradation of biopolymers},
  series = {Sensors and actuators B: Chemical},
  volume    = {207, Part B},
  journal   = {Sensors and actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-3077 (E-Journal); 0925-4005 (Print)},
  doi       = {10.1016/j.snb.2014.10.058},
  pages     = {954 -- 959},
  year      = {2015},
  abstract  = {The characterization of the degradation kinetics of biodegradable polymers is mandatory with regard to their proper application. In the present work, polymer-modified electrolyte-insulator-semiconductor (PMEIS) field-effect sensors have been applied for in-situ monitoring of the pH-dependent degradation kinetics of the commercially available biopolymer poly(d,l-lactic acid) (PDLLA) in buffer solutions from pH 3 to pH 13. PDLLA films of 500 nm thickness were deposited on the surface of an Al-p-Si-SiO2-Ta2O5 structure from a polymer solution by means of spin-coating method. The PMEIS sensor is, in principle, capable to detect any changes in bulk, surface and interface properties of the polymer induced by degradation processes. A faster degradation has been observed for PDLLA films exposed to alkaline solutions (pH 9, pH 11 and pH 13).},
  language  = {en}
}
@article{SeifarthGossmannGrosseetal.2015,
  author    = {Seifarth, Volker and Goßmann, Matthias and Grosse, J. O. and Becker, C. and Heschel, I. and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l},
  title     = {Development of a Bioreactor to Culture Tissue Engineered Ureters Based on the Application of Tubular OPTIMAIX 3D Scaffolds},
  series = {Urologia Internationalis},
  volume    = {2015},
  journal   = {Urologia Internationalis},
  number    = {95},
  publisher = {Karger},
  address   = {Basel},
  issn      = {0042-1138},
  doi       = {10.1159/000368419},
  pages     = {106 -- 113},
  year      = {2015},
  language  = {en}
}
@article{SeynnesBojsenMollerAlbrachtetal.2015,
  author    = {Seynnes, O. R. and Bojsen-Moller, J. and Albracht, Kirsten and Arndt, A. and Cronin, N. J. and Finni, T. and Magnusson, S. P.},
  title     = {Ultrasound-based testing of tendon mechanical properties: a critical evaluation},
  series = {Journal of Applied Physiology},
  volume    = {118},
  journal   = {Journal of Applied Physiology},
  number    = {2},
  issn      = {8750-7587},
  doi       = {10.1152/japplphysiol.00849.2014},
  pages     = {133 -- 141},
  year      = {2015},
  language  = {en}
}
@article{TaddeiButenwegKlinkel2015,
  author    = {Taddei, Francesca and Butenweg, Christoph and Klinkel, S.},
  title     = {Parametric investigation of the soil-structure interaction effects on the dynamic behaviour of a shallow foundation supported wind turbine considering a layered soil},
  series = {Wind energy : an international journal for progress and applications in wind power conversion technology},
  volume    = {Volume 18},
  journal   = {Wind energy : an international journal for progress and applications in wind power conversion technology},
  number    = {Issue 3},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1099-1824 (E-Journal); 1095-4244 (Print)},
  doi       = {10.1002/we.1703},
  pages     = {399 -- 417},
  year      = {2015},
  language  = {en}
}
@article{TakenagaSchneiderErbayetal.2015,
  author    = {Takenaga, Shoko and Schneider, Benno and Erbay, E. and Biselli, Manfred and Schnitzler, Thomas and Sch{\"o}ning, Michael Josef and Wagner, Torsten},
  title     = {Fabrication of biocompatible lab-on-chip devices for biomedical applications by means of a 3D-printing process},
  series = {Physica status solidi (a)},
  volume    = {212},
  journal   = {Physica status solidi (a)},
  number    = {6},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201532053},
  pages     = {1347 -- 1352},
  year      = {2015},
  abstract  = {A new microfluidic assembly method for semiconductor-based biosensors using 3D-printing technologies was proposed for a rapid and cost-efficient design of new sensor systems. The microfluidic unit is designed and printed by a 3D-printer in just a few hours and assembled on a light-addressable potentiometric sensor (LAPS) chip using a photo resin. The cell growth curves obtained from culturing cells within microfluidics-based LAPS systems were compared with cell growth curves in cell culture flasks to examine biocompatibility of the 3D-printed chips. Furthermore, an optimal cell culturing within microfluidics-based LAPS chips was achieved by adjusting the fetal calf serum concentrations of the cell culture medium, an important factor for the cell proliferation.},
  language  = {en}
}
@article{ThielMufflerTippkoetteretal.2015,
  author    = {Thiel, Alexander and Muffler, Kai and Tippk{\"o}tter, Nils and Suck, Kirstin and Sohling, Ulrich and Hruschka, Steffen M. and Ulber, Roland},
  title     = {A novel integrated downstream processing approach to recover sinapic acid, phytic acid and proteins from rapeseed meal},
  series = {Journal of Chemical Technology and Biotechnology},
  volume    = {90},
  journal   = {Journal of Chemical Technology and Biotechnology},
  number    = {11},
  publisher = {Wiley},
  address   = {Weinheim},
  doi       = {10.1002/jctb.4664},
  pages     = {1999 -- 2006},
  year      = {2015},
  abstract  = {BACKGROUND Currently, several techniques exist for the downstream processing of protein, phytic acid and sinapic acid from rapeseed and rapeseed meal, but no technique has been developed to separate all of the components in one process. In this work, two new downstream processing strategies focusing on recovering sinapic acid, phytic acid and protein from rapeseed meal were established. RESULTS The sinapic acid content was enhanced by a factor of 4.5 with one method and 5.1 with the other. The isolation of sinapic acid was accomplished using a zeolite-based adsorbent with high adsorptive and optimal desorption characteristics. Phytic acid was isolated using the anion-exchange resin Purolite A200®. In addition, the processes resulted in two separated protein fractions. The ratios of globulin and albumin ratio to the total protein were 59.2\% and 40.1\%, respectively. The steps were then combined in two different ways: (a) a 'sequential process' using the zeolite and A200 in batch processes; and (b) a 'parallel process' using only A200 in a chromatographic system to separate all of the compounds. CONCLUSIONS It can be concluded that isolation of all three components was possible in both processes. These could enhance the added value of current processes using rapeseed meal as a protein source. © 2015 Society of Chemical Industry},
  language  = {en}
}
@article{VoigtAlbrechtSieversetal.2015,
  author    = {Voigt, Birgit and Albrecht, Dirk and Sievers, Susanne and Becher, D{\"o}rte and Bongaerts, Johannes and Evers, Stefan and Schweder, Thomas and Maurer, Karl-Heinz and Hecker, Michael},
  title     = {High-resolution proteome maps of Bacillus licheniformis cells growing in minimal medium},
  series = {Proteomics},
  volume    = {15},
  journal   = {Proteomics},
  number    = {15},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1615-9861},
  doi       = {10.1002/pmic.201400504},
  pages     = {2629 -- 2633},
  year      = {2015},
  language  = {en}
}
@article{WarmerWagnerSchoeningetal.2015,
  author    = {Warmer, Johannes and Wagner, Patrick and Sch{\"o}ning, Michael Josef and Kaul, Peter},
  title     = {Detection of triacetone triperoxide using temperature cycled metal-oxide semiconductor gas sensors},
  series = {Physica status solidi (a)},
  volume    = {212},
  journal   = {Physica status solidi (a)},
  number    = {6},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201431882},
  pages     = {1289 -- 1298},
  year      = {2015},
  language  = {en}
}
@article{WiesenTippkoetterMuffleretal.2015,
  author    = {Wiesen, Sebastian and Tippk{\"o}tter, Nils and Muffler, Kai and Suck, Kirstin and Sohling, Ulrich and Ruf, Friedrich and Ulber, Roland},
  title     = {Adsorption of fatty acids to layered double hydroxides in aqueous systems},
  series = {Adsorption},
  volume    = {21},
  journal   = {Adsorption},
  number    = {6-7},
  publisher = {Springer},
  address   = {Berlin},
  pages     = {459 -- 466},
  year      = {2015},
  abstract  = {Due to their anion exchange characteristics, layered double hydroxides (LDHs) are suitable for the detoxification of aqueous, fatty acid containing fermentation substrates. The aim of this study is to examine the adsorption mechanism, using crude glycerol from plant oil esterification as a model system. Changes in the intercalation structure in relation to the amount of fatty acids adsorbed are monitored by X-ray diffraction and infra-red spectroscopy. Additionally, calcination of LDH is investigated in order to increase the binding capacity for fatty acids. Our data propose that, at ambient temperature, fatty acids can be bound to the hydrotalcite by adsorption or in addition by intercalation, depending on fatty acid concentration. The adsorption of fatty acids from crude glycerol shows a BET-like behavior. Above a fatty acid concentration of 3.5 g L-1, intercalation of fatty acids can be shown by the appearance of an increased interlayer spacing. This observation suggests a two phase adsorption process. Calcination of LDHs allows increasing the binding capacity for fatty acids by more than six times, mainly by reduction of structural CO32-.},
  language  = {en}
}