@article{Olbertz2021, author = {Olbertz, Klaus}, title = {Die Flexibilisierung von Arbeitszeit durch den Abruf von Arbeit : M{\"o}glichkeiten und Grenzen arbeitsvertraglicher Gestaltung zur Vermeidung von „Leerlaufzeiten"}, series = {NWB - Steuer- und Wirtschaftsrecht}, journal = {NWB - Steuer- und Wirtschaftsrecht}, number = {15}, issn = {0028-3460}, pages = {1055 -- 1063}, year = {2021}, abstract = {Die Arbeitswelt ist im Umbruch. Der Bedarf an flexiblen Arbeitszeitmodellen nimmt stetig zu, wobei die Corona-Pandemie dieses Bed{\"u}rfnis nochmals versch{\"a}rft hat. Gerade auch in kleineren und mittleren Unternehmen w{\"a}chst die Notwendigkeit, den Einsatz der Besch{\"a}ftigten m{\"o}glichst bedarfsgerecht zu steuern, also bei guter Auftragslage mehr Arbeitszeit abzurufen und bei ausbleibenden Auftr{\"a}gen die Arbeitszeit zu reduzieren und somit bezahlte „Leerlaufzeiten" zu vermeiden. Der Gesetzgeber stellt den Arbeitgebern hierf{\"u}r das Instrument der sog. Abrufarbeit ( \S 12 Teilzeit- und Befristungsgesetz - TzBfG ) zur Verf{\"u}gung. In dem nachfolgenden Beitrag werden M{\"o}glichkeiten und Grenzen der Abrufarbeit skizziert und konkrete arbeitsvertragliche Gestaltungsm{\"o}glichkeiten aufgezeigt.}, language = {de} } @article{Olbertz2021, author = {Olbertz, Klaus}, title = {Vertragsgestaltungen bei der Besch{\"a}ftigung von Rentnern in Unternehmen : (Befristete) Besch{\"a}ftigungsverh{\"a}ltnisse als sinnvolles Instrument zum Schließen von Personall{\"u}cken}, series = {NWB - Steuer- und Wirtschaftsrecht}, journal = {NWB - Steuer- und Wirtschaftsrecht}, number = {25}, issn = {0028-3460}, pages = {1810 -- 1817}, year = {2021}, language = {de} } @inproceedings{NikolovskiRekeElsenetal.2021, author = {Nikolovski, Gjorgji and Reke, Michael and Elsen, Ingo and Schiffer, Stefan}, title = {Machine learning based 3D object detection for navigation in unstructured environments}, series = {2021 IEEE Intelligent Vehicles Symposium Workshops (IV Workshops)}, booktitle = {2021 IEEE Intelligent Vehicles Symposium Workshops (IV Workshops)}, publisher = {IEEE}, isbn = {978-1-6654-7921-9}, doi = {10.1109/IVWorkshops54471.2021.9669218}, pages = {236 -- 242}, year = {2021}, abstract = {In this paper we investigate the use of deep neural networks for 3D object detection in uncommon, unstructured environments such as in an open-pit mine. While neural nets are frequently used for object detection in regular autonomous driving applications, more unusual driving scenarios aside street traffic pose additional challenges. For one, the collection of appropriate data sets to train the networks is an issue. For another, testing the performance of trained networks often requires tailored integration with the particular domain as well. While there exist different solutions for these problems in regular autonomous driving, there are only very few approaches that work for special domains just as well. We address both the challenges above in this work. First, we discuss two possible ways of acquiring data for training and evaluation. That is, we evaluate a semi-automated annotation of recorded LIDAR data and we examine synthetic data generation. Using these datasets we train and test different deep neural network for the task of object detection. Second, we propose a possible integration of a ROS2 detector module for an autonomous driving platform. Finally, we present the performance of three state-of-the-art deep neural networks in the domain of 3D object detection on a synthetic dataset and a smaller one containing a characteristic object from an open-pit mine.}, language = {en} } @masterthesis{Niederschmidt2021, type = {Bachelor Thesis}, author = {Niederschmidt, S{\"o}ren}, title = {Living product: ein Ansatz, lebendige Organismen mit einem Produkt zu vereinen und nutzbar zu machen}, publisher = {FH Aachen}, address = {Aachen}, pages = {57 Seiten}, year = {2021}, abstract = {Diese Arbeit setzt sich mit der Frage auseinander, in welcher Form sich lebendige Organismen - hier insbesondere Pilze - in die Produktwelt integrieren lassen. In welcher Art und Weise beeinflusst ein Organismus das Produkterlebnis? Im Rahmen dieser Arbeit sind vier verschiedene Produkte entstanden, die die St{\"a}rken des Materials Myzelium demonstrieren. Myzelium bezeichnet das sehr dichte Wurzelnetzwerk eines Pilzes. Dieses lebendige Netzwerk kann dazu genutzt werden, um organische Stoffe miteinander zu verwachsen und somit Formen entstehen zu lassen. Die so entstandenen Produkte sind in eine Konzeptumgebung eingebettet, in der der Verbrauchende die Natur durch naturn{\"a}here Produkte (Form, Material und gewachsene Strukturen) neu erlebt. Gezeigt wird ein Packaging f{\"u}r Einmachgl{\"a}ser, ein Kressebeet, ein Wandregal und ein Teelicht.}, language = {de} } @masterthesis{Niedermeier2021, type = {Bachelor Thesis}, author = {Niedermeier, Jacqueline}, title = {Aachener Tierpark Euregiozoo: Corporate Design f{\"u}r eine Institution mit Bildungsauftrag}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {107 Seiten}, year = {2021}, abstract = {Der Aachener Tierpark Euregiozoo l{\"a}sst die Aspekte "Bildung" und "Forschung" mit "Erholung" und "Erhaltung" an einem Ort miteinander verschmelzen. Auf einer Fl{\"a}che von rund 8,9 ha beherbergt der Zoo etwa 1.000 Tiere aus 200 verschiedenen Arten und Rassen in großz{\"u}gigen und nat{\"u}rlich gestalteten Gehegen. Das neue Designkonzept soll den Bildungsaspekt in den Vordergrund r{\"u}cken und modernisieren. Der Einsatz verschiedenster Medien soll die breite Zielgruppe von Jung bis Alt ansprechen und das Interesse nach neuem Wissen anregen. Das neue Leitsystem sorgt nicht nur f{\"u}r Orientierung im Park, es erm{\"o}glicht auch interaktive und individuelle F{\"u}hrungen durch den Zoo. Kombiniert mit einem Wissensquiz und zahlreichen spannenden Fakten {\"u}ber die Tierwelt des Parks wird der Zoobesuch zu einem ganz besonderen Erlebnis.}, language = {de} } @inproceedings{NeumannAdamBackesetal.2021, author = {Neumann, Hannah and Adam, Mario and Backes, Klaus and B{\"o}rner, Martin and Clees, Tanja and Doetsch, Christian and Glaeser, Susanne and Herrmann, Ulf and May, Johanna and Rosenthal, Florian and Sauer, Dirk Uwe and Stadler, Ingo}, title = {Development of open educational resources for renewable energy and the energy transition process}, series = {ISES SWC 2021}, booktitle = {ISES SWC 2021}, publisher = {International Solar Energy Society}, address = {Freiburg}, doi = {10.18086/swc.2021.47.03}, pages = {6 Seiten}, year = {2021}, abstract = {The dissemination of knowledge about renewable energies is understood as a social task with the highest topicality. The transfer of teaching content on renewable energies into digital open educational resources offers the opportunity to significantly accelerate the implementation of the energy transition. Thus, in the here presented project six German universities create open educational resources for the energy transition. These materials are available to the public on the internet under a free license. So far there has been no publicly accessible, editable media that cover entire learning units about renewable energies extensively and in high technical quality. Thus, in this project, the content that remains up-to-date for a longer period is appropriately prepared in terms of media didactics. The materials enable lecturers to provide students with in-depth training about technologies for the energy transition. In a particular way, the created material is also suitable for making the general public knowledgeable about the energy transition with scientifically based material.}, language = {en} } @article{NeumaierWeissVeldemanetal.2021, author = {Neumaier, Felix and Weiss, Miriam and Veldeman, Michael and Kotliar, Konstantin and Wiesmann, Martin and Schulze-Steinen, Henna and H{\"o}llig, Anke and Clusmann, Hans and Schubert, Gerrit Alexander and Albanna, Walid}, title = {Changes in endogenous daytime melatonin levels after aneurysmal subarachnoid hemorrhage - preliminary findings from an observational cohort study}, series = {Clinical Neurology and Neurosurgery}, volume = {208}, journal = {Clinical Neurology and Neurosurgery}, number = {Article No.: 106870}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0303-8467}, doi = {10.1016/j.clineuro.2021.106870}, year = {2021}, abstract = {Aneurysmal subarachnoid hemorrhage (aSAH) is associated with early and delayed brain injury due to several underlying and interrelated processes, which include inflammation, oxidative stress, endothelial, and neuronal apoptosis. Treatment with melatonin, a cytoprotective neurohormone with anti-inflammatory, anti-oxidant and anti-apoptotic effects, has been shown to attenuate early brain injury (EBI) and to prevent delayed cerebral vasospasm in experimental aSAH models. Less is known about the role of endogenous melatonin for aSAH outcome and how its production is altered by the pathophysiological cascades initiated during EBI. In the present observational study, we analyzed changes in melatonin levels during the first three weeks after aSAH.}, language = {en} } @article{NeumaierKotliarHaerenetal.2021, author = {Neumaier, Felix and Kotliar, Konstantin and Haeren, Roel Hubert Louis and Temel, Yasin and L{\"u}ke, Jan Niklas and Seyam, Osama and Lindauer, Ute and Clusmann, Hans and Hescheler, J{\"u}rgen and Schubert, Gerrit Alexander and Schneider, Toni and Albanna, Walid}, title = {Retinal Vessel Responses to Flicker Stimulation Are Impaired in Ca v 2.3-Deficient Mice—An in- vivo Evaluation Using Retinal Vessel Analysis (RVA)}, series = {Frontiers in Neurology}, volume = {12}, journal = {Frontiers in Neurology}, publisher = {Frontiers}, doi = {10.3389/fneur.2021.659890}, pages = {1 -- 11}, year = {2021}, language = {en} } @masterthesis{Najarov2021, type = {Bachelor Thesis}, author = {Najarov, Azer}, title = {Ich sehe was, was Du nicht siehst: Herkunft \& Identit{\"a}t j{\"u}discher Menschen in Deutschland nach der Nachkriegszeit}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {105 Seiten}, year = {2021}, abstract = {Wir alle haben schon einmal von ihnen geh{\"o}rt. Die einen kennen sie aus dem Geschichtsunterricht, die anderen haben sie vielleicht auch schon mal bewusst oder unbewusst auf der Straße gesehen. Einige sind es sogar selbst. Die Rede ist von j{\"u}dischen Menschen in Deutschland. In unserer Bundesrepublik wird die j{\"u}dische Bev{\"o}lkerung unausweichlich mit dem Gedanken des Holocausts verbunden. J{\"u}dinnen und Juden wird somit eine Identit{\"a}t zugesprochen, mit der sie nichts zu tun haben. Es findet eine Stigmatisierung statt. Dabei sind j{\"u}dische Menschen heutzutage so divers wie noch nie. Das Printmedium »Ich sehe was, was Du nicht siehst« beleuchtet diese selten wahrgenommene Diversit{\"a}t und zeigt durch spannende Interviews eine j{\"u}dische Welt, die außerhalb der NS-Verbrechen liegt. Dar{\"u}ber hinaus findet man Informationen zu verschiedenen j{\"u}dischen Br{\"a}uchen, historischen Ereignissen und interessanten Infografiken. }, language = {de} } @misc{Nahrstedt2021, type = {Master Thesis}, author = {Nahrstedt, Sarah}, title = {Any Cargo: Das Fahrrad als Hauptverkehrsmittel in der Stadt}, publisher = {FH Aachen}, address = {Aachen}, pages = {216 Seiten}, year = {2021}, abstract = {Durch die Urbanisierung, wird es in St{\"a}dten immer enger und der Verkehr nimmt zu. Das hat hohe Emissionen und Platzmangel zur Folge. In der Masterarbeit wurde die Abh{\"a}ngigkeit zum Auto in der Stadt hinterfragt und ein Konzept erarbeitet, welches die Autonutzung und den Autobesitz abl{\"o}st. Dabei entstand ein neuer Fahrradanh{\"a}nger, der eine multifunktionale Nutzung zul{\"a}sst und einen elektrischen Antrieb besitzt. Dadurch bietet er einen komfortablen Support im Alltag. Zudem wurde ein Gesch{\"a}ftskonzept entwickelt, welches erm{\"o}glicht, den Anh{\"a}nger mit einem digitalen Ausleihsystem unter Nachbarn oder Freunden zu teilen. Ein wichtiges Kriterium f{\"u}r das Produkt und den Service war, dass die Mobilit{\"a}t der Zukunft nicht nur nachhaltig sein soll, sondern auch Laune machen muss.}, language = {de} } @inproceedings{MuellerSchmittLeiseetal.2021, author = {M{\"u}ller, Tim M. and Schmitt, Andreas and Leise, Philipp and Meck, Tobias and Altherr, Lena and Pelz, Peter F. and Pfetsch, Marc E.}, title = {Validation of an optimized resilient water supply system}, series = {Uncertainty in Mechanical Engineering}, booktitle = {Uncertainty in Mechanical Engineering}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-77255-0}, doi = {10.1007/978-3-030-77256-7_7}, pages = {70 -- 80}, year = {2021}, abstract = {Component failures within water supply systems can lead to significant performance losses. One way to address these losses is the explicit anticipation of failures within the design process. We consider a water supply system for high-rise buildings, where pump failures are the most likely failure scenarios. We explicitly consider these failures within an early design stage which leads to a more resilient system, i.e., a system which is able to operate under a predefined number of arbitrary pump failures. We use a mathematical optimization approach to compute such a resilient design. This is based on a multi-stage model for topology optimization, which can be described by a system of nonlinear inequalities and integrality constraints. Such a model has to be both computationally tractable and to represent the real-world system accurately. We therefore validate the algorithmic solutions using experiments on a scaled test rig for high-rise buildings. The test rig allows for an arbitrary connection of pumps to reproduce scaled versions of booster station designs for high-rise buildings. We experimentally verify the applicability of the presented optimization model and that the proposed resilience properties are also fulfilled in real systems.}, language = {en} } @masterthesis{Mueller2021, type = {Bachelor Thesis}, author = {M{\"u}ller, Elona}, title = {Aus den Augen aus dem Sinn?: Ein Bookazine deckt das Problem des Unsichtbaren M{\"u}lls auf}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, year = {2021}, abstract = {M{\"u}ll ist immer und {\"u}berall vorhanden - auch wenn wir ihn nicht sehen. Gerade unsichtbarer M{\"u}ll birgt f{\"u}r den Menschen und seine Umwelt erhebliche Gefahren, die durch seine Unsichtbarkeit irrelevant erscheinen. Die Publikation mit dem Titel mikromakro deckt durch verschiedene Artikel, Interviews und Texte die Gefahren auf, die durch den unsichtbaren M{\"u}ll entstehen. Ziel war es, eine Bookazine-Reihe zu konzipieren, die in sechs Ausgaben das Thema des unsichtbaren M{\"u}lls beleuchtet. Die erste Ausgabe zum Thema Kunststoff wurde exemplarisch gestaltet. Zus{\"a}tzlich zum redaktionellen Teil untermauern Infografiken die Texte faktisch und Fotoserien emotional. Da unsichtbarer M{\"u}ll auf zwei Ebenen zu finden ist - der Makro- (groß) und Mikroebene (klein) - wurde die Publikation inhaltlich zweigeteilt, sodass sich das Layout und die Fotoserien vom Mikro- und Makroteil unterscheiden. }, language = {de} } @masterthesis{Muehl2021, type = {Bachelor Thesis}, author = {M{\"u}hl, Leonie}, title = {Neues Erscheinungsbild f{\"u}r den APX: Redesign des LVR - Arch{\"a}ologischen Park Xanten und des R{\"o}mermuseums}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {90 Seiten}, year = {2021}, abstract = {Der Arch{\"a}ologische Park Xanten (APX) gilt als Deutschlands einziger arch{\"a}ologischer Freiluftpark. Er zeichnet sich im Verbund mit dem R{\"o}mermuseum durch seine Lage auf dem historischen Grund einer r{\"o}mischen Metropole und seine kontinuierliche Forschungsaktivit{\"a}t aus und bietet so ein einzigartiges Umfeld von kultureller Relevanz. Ziel dieses Projektes war es, ein neues Erscheinungsbild zu entwickeln, welches klar die Thematik des Parks in den Medien erkennbar macht. Das Corporate Design dient dazu, die Inhalte des Verbundes in einem einheitlichen System medien{\"u}bergreifend zu pr{\"a}sentieren. Das Design unterst{\"u}tzt den APX in seiner Funktion als Begegnungs- und Bildungsst{\"a}tte. Aufgrund dessen ist es im Hinblick auf das Ziel relevant, das Interesse an Kulturgeschichte und Forschung zu wecken.}, language = {de} } @masterthesis{Mros2021, type = {Bachelor Thesis}, author = {Mros, Christina}, title = {Entwicklung eines Erscheinungsbildes sowie einer Kampagne f{\"u}r die Allianz Chronischer Seltener Erkrankungen}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {89 Seiten}, year = {2021}, abstract = {Die Allianz Chronischer Seltener Erkrankungen (ACHSE) ist das einzige krankheits{\"u}bergreifende Netzwerk von und f{\"u}r Menschen mit einer seltenen Erkrankung in Deutschland. Insgesamt sind 4 Millionen Menschen in Deutschland von einer der rund 8.000 seltenen Krankheiten betroffen. Durch die Seltenheit der verschiedenen Krankheiten ist es oft schwer, Experten zu finden, die richtige Versorgung sicherzustellen oder Studien durchzuf{\"u}hren. Betroffene f{\"u}hlen sich oft nicht wahrgenommen und alleine gelassen. Die ACHSE dient als unabh{\"a}ngige Schnittstelle und Knotenpunkt zwischen Betroffenen, Regierung, Politik und Wirtschaft. Gemeinsam b{\"u}ndeln sich hier 130 Patientenorganisationen unter einem Dach, um die Betroffenen in den Fokus zu r{\"u}cken. Ziel der Bachelorarbeit ist die Entwicklung eines Erscheinungsbildes sowie einer Kampagne, die das Thema mehr ins Bewusstsein der {\"O}ffentlichkeit bringt und informiert.}, language = {de} } @article{MontiWaldvogelRitzmannetal.2021, author = {Monti, Elena and Waldvogel, Janice and Ritzmann, Ramona and Freyler, Kathrin and Albracht, Kirsten and Helm, Michael and De Cesare, Niccol{\`o} and Pavan, Piero and Reggiani, Carlo and Gollhofer, Albert and Narici, Marco Vincenzo}, title = {Muscle in variable gravity: "I do not know where I am, but I know what to do"}, series = {Frontiers in Physiology}, volume = {12}, journal = {Frontiers in Physiology}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-042X}, doi = {10.3389/fphys.2021.714655}, pages = {19 Seiten}, year = {2021}, abstract = {Performing tasks, such as running and jumping, requires activation of the agonist and antagonist muscles before (motor unit pre-activation) and during movement performance (Santello and Mcdonagh, 1998). A well-timed and regulated muscle activation elicits a stretch-shortening cycle (SSC) response, naturally occurring in bouncing movements (Ishikawa and Komi, 2004; Taube et al., 2012). By definition, the SSC describes the stretching of a pre-activated muscle-tendon complex immediately followed by a muscle shortening in the concentric push-off phase (Komi, 1984). Given the importance of SSC actions for human movement, it is not surprising that many studies investigated the biomechanics of this phenomenon; in particular, drop jumps (DJs) represent a good paradigm to study muscle fascicle and tendon behavior in ballistic movements involving the SSC. Within a DJ, three main phases [pre-activation, braking, and push-off (PO; Komi, 2000)] have been recognized and extensively studied in common and challenging conditions, such as changes in load, falling height, or simulated hypo-gravity (Avela et al., 1994; Arampatzis et al., 2001; Fukashiro et al., 2005; Ishikawa et al., 2005; Sousa et al., 2007; Ritzmann et al., 2016; Helm et al., 2020). These studies show that the timing and amount of triceps-surae muscle-tendon unit pre-activation in DJs are differentially regulated based on the load applied to the muscle, being optimal in normal "Earth" gravity conditions (Avela et al., 1994), but decreased in simulated hypo-gravity, hyper-gravity (Avela et al., 1994; Ritzmann et al., 2016), or unknown conditions (i.e., unknown falling heights; Helm et al., 2020). Some authors indicated that, when falling from heights different from the optimal one [defined as the drop height giving a maximum DJ performance indicated as peak ground reaction force (GRF) or jump high], electromyographic (EMG) activity of the plantar flexors increases from lower than optimal to higher than optimal heights (Ishikawa and Komi, 2004; Sousa et al., 2007). These findings highlight the ability of the central nervous system to regulate the timing and amount of pre-activation according to different jumping conditions, thus regulating muscle fascicle length, tendon and joint stiffness as well as position, in order to safely land on the ground and quickly re-bounce. Similarly, to pre-activation, also in the braking phase, the plantar flexors are differentially regulated. In optimal height (i.e., load) jumping conditions, gastrocnemius medialis (GM) fascicles shorten at early ground contact (possibly due to the intervention of the stretch reflex; Gollhofer et al., 1992) and behave quasi-isometrically in the late braking phase, enabling tendon elongation, and storage of elastic energy (Gollhofer et al., 1992; Fukashiro et al., 2005; Sousa et al., 2007). When increasing the falling height (augmenting the impact GRF), the quasi-isometric behavior of fascicles disappears, and fast fascicle lengthening occurs (Ishikawa et al., 2005; Sousa et al., 2007). In the third and last PO phase, fascicles shorten and the tendon releases the elastic energy previously stored. Bobbert et al. (1987) reported no influence of jumping height on the work done and on the net vertical impulse assessed during PO; this observation suggests that, despite an optimal DJ performance might be achieved only in specific conditions (falling heights, loads), the central nervous system seems to be able to regulate muscle behavior in order to effectively perform the required task also in challenging situations. Although the regulation of triceps-surae muscle-tendon unit in DJs has been extensively investigated, very few studies focused on sarcomeres behavior during the performance of this SSC movement (Kurokawa et al., 2003; Fukashiro et al., 2005, 2006). Sarcomeres represent muscle contractile units and are known to express different amounts of force depending on their length (Gordon et al., 1966; Walker and Schrodt, 1974); thus, understanding the time course of their responses during DJs is fundamental to gain further insights into muscle force-generating capacity. In vivo measurement of sarcomere length in humans has been so far been performed only in static positions and under highly controlled experimental conditions (Llewellyn et al., 2008; Sanchez et al., 2015). Instead, human sarcomere length estimation (achieved by dividing GM measured fascicle length for a fixed sarcomere number) in dynamic contractions provided an indirect measure of sarcomere operating range during squat jump, countermovement jump, and DJ (Fukashiro et al., 2005, 2006; Kurokawa et al., 2003). The results of these studies showed that sarcomeres operate in the ascending limb of their length-tension (L-T) relationship in all types of jumps, and particularly so in DJ. However, most of the available observations on sarcomere and muscle fascicle behavior were made in condition of constant gravity. Thus, in order to understand how sarcomere and muscle fascicle length are regulated in variable gravity conditions, we performed experiments in a parabolic flight, involving variable gravity levels, ranging from about zero-g to about double the Earth's gravity (1 g; Waldvogel et al., 2021). Specifically, the aims of the present study were as follows: 1. To investigate the ability of the neuromuscular system in regulating fascicle length in response to conditions of variable gravity. 2. To estimate sarcomere operative length in the different DJ phases, in order to calculate its theoretical force production and its possible modulation in conditions of variable gravity. We hypothesized that muscle fascicles would be differentially regulated in different gravity conditions compared to 1 g, particularly in anticipation of landing and re-bouncing in unknown gravity levels. In addition, we hypothesized that sarcomeres would operate in the upper part of the ascending limb of their L-T relationship, possibly lengthening during the braking phase (especially in hyper-gravity) while operating quasi-isometrically in 1 g.}, language = {en} } @misc{Monse2021, type = {Master Thesis}, author = {Monse, Henry}, title = {(K)eine Opposition: Die Wahlkampfgestaltung der SPD und CDU von 1945—1990 im historischen Kontext}, publisher = {FH Aachen}, address = {Aachen}, pages = {66 Seiten}, year = {2021}, abstract = {Im Zentrum des Buches stehen die beiden Volksparteien CDU und SPD, die sich als gegens{\"a}tzliche, gar verfeindete Parteien startend, gegenw{\"a}rtig in ihren visuellen und inhaltlichen Identit{\"a}ten immer unerkenntlicher vermischen. Das Buch geht dem Ursprung dieser Vermischung auf die Spur und untersucht inwiefern sich die visuellen Identit{\"a}ten der beiden Parteien zwischen 1945 und 1990 in Form der Gestaltung nach außen aneinander angeglichen haben und wer wann federf{\"u}hrend in der Gestaltung war. Beginnend 1945 in der »Stunde Null« f{\"u}hrt das Buch in den einzelnen Kapiteln durch das Zeitgeschehen der Bundesrepublik bis ins Jahr 1990. Der historische Querschnitt beleuchtet dabei das gesellschaftspolitische Zeitgeschehen, das den Wahlk{\"a}mpfen zugrunde liegt. Dabei stehen die politischen Wahlplakate im Fokus der Untersuchung: SPD und CDU — (k)eine gestalterische Opposition?}, language = {de} } @article{MonakhovaDiehl2021, author = {Monakhova, Yulia and Diehl, Bernd W.K.}, title = {Novel approach of qNMR workflow by standardization using 2H integral: Application to any intrinsic calibration standard}, series = {Talanta}, volume = {222}, journal = {Talanta}, number = {Article number: 121504}, publisher = {Elsevier}, isbn = {0039-9140}, doi = {10.1016/j.talanta.2020.121504}, year = {2021}, abstract = {Quantitative nuclear magnetic resonance (qNMR) is routinely performed by the internal or external standardization. The manuscript describes a simple alternative to these common workflows by using NMR signal of another active nuclei of calibration compound. For example, for any arbitrary compound quantification by NMR can be based on the use of an indirect concentration referencing that relies on a solvent having both 1H and 2H signals. To perform high-quality quantification, the deuteration level of the utilized deuterated solvent has to be estimated. In this contribution the new method was applied to the determination of deuteration levels in different deuterated solvents (MeOD, ACN, CDCl3, acetone, benzene, DMSO-d6). Isopropanol-d6, which contains a defined number of deuterons and protons, was used for standardization. Validation characteristics (precision, accuracy, robustness) were calculated and the results showed that the method can be used in routine practice. Uncertainty budget was also evaluated. In general, this novel approach, using standardization by 2H integral, benefits from reduced sample preparation steps and uncertainties, and can be applied in different application areas (purity determination, forensics, pharmaceutical analysis, etc.).}, language = {en} } @article{MonakhovaDiehl2021, author = {Monakhova, Yulia and Diehl, Bernd W. K.}, title = {Simplification of NMR Workflows by Standardization Using 2H Integral of Deuterated Solvent as Applied to Aloe vera Preparations}, series = {Applied Magnetic Resonance}, volume = {52}, journal = {Applied Magnetic Resonance}, number = {11}, publisher = {Springer}, address = {Cham}, issn = {1613-7507}, doi = {10.1007/s00723-021-01393-4}, pages = {1591 -- 1600}, year = {2021}, abstract = {In this study, a recently proposed NMR standardization approach by 2H integral of deuterated solvent for quantitative multicomponent analysis of complex mixtures is presented. As a proof of principle, the existing NMR routine for the analysis of Aloe vera products was modified. Instead of using absolute integrals of targeted compounds and internal standard (nicotinamide) from 1H-NMR spectra, quantification was performed based on the ratio of a particular 1H-NMR compound integral and 2H-NMR signal of deuterated solvent D2O. Validation characteristics (linearity, repeatability, accuracy) were evaluated and the results showed that the method has the same precision as internal standardization in case of multicomponent screening. Moreover, a dehydration process by freeze drying is not necessary for the new routine. Now, our NMR profiling of A. vera products needs only limited sample preparation and data processing. The new standardization methodology provides an appealing alternative for multicomponent NMR screening. In general, this novel approach, using standardization by 2H integral, benefits from reduced sample preparation steps and uncertainties, and is recommended in different application areas (purity determination, forensics, pharmaceutical analysis, etc.).}, language = {en} } @article{MonakhovaDiehl2021, author = {Monakhova, Yulia and Diehl, Bernd W. K.}, title = {A step towards optimization of the qNMR workflow: proficiency testing exercise at an GxP-accredited laboratory}, series = {Applied Magnetic Resonance}, volume = {52}, journal = {Applied Magnetic Resonance}, publisher = {Springer Nature}, address = {Wien}, issn = {1613-7507}, doi = {10.1007/s00723-021-01324-3}, pages = {581 -- 593}, year = {2021}, abstract = {Quantitative nuclear magnetic resonance (qNMR) is considered as a powerful tool for multicomponent mixture analysis as well as for the purity determination of single compounds. Special attention is currently paid to the training of operators and study directors involved in qNMR testing. To assure that only qualified personnel are used for sample preparation at our GxP-accredited laboratory, weighing test was proposed. Sixteen participants performed six-fold weighing of the binary mixture of dibutylated hydroxytoluene (BHT) and 1,2,4,5-tetrachloro-3-nitrobenzene (TCNB). To evaluate the quality of data analysis, all spectra were evaluated manually by a qNMR expert and using in-house developed automated routine. The results revealed that mean values are comparable and both evaluation approaches are free of systematic error. However, automated evaluation resulted in an approximately 20\% increase in precision. The same findings were revealed for qNMR analysis of 32 compounds used in pharmaceutical industry. Weighing test by six-fold determination in binary mixtures and automated qNMR methodology can be recommended as efficient tools for evaluating staff proficiency. The automated qNMR method significantly increases throughput and precision of qNMR for routine measurements and extends application scope of qNMR.}, language = {en} } @article{MolinnusDrinicIkenetal.2021, author = {Molinnus, Denise and Drinic, Aleksander and Iken, Heiko and Kr{\"o}ger, Nadja and Zinser, Max and Smeets, Ralf and K{\"o}pf, Marius and Kopp, Alexander and Sch{\"o}ning, Michael Josef}, title = {Towards a flexible electrochemical biosensor fabricated from biocompatible Bombyx mori silk}, series = {Biosensors and Bioelectronics}, volume = {183}, journal = {Biosensors and Bioelectronics}, number = {Art. 113204}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0956-5663}, doi = {10.1016/j.bios.2021.113204}, year = {2021}, language = {en} }