@article{SelmerHallmannSchmidtetal.1996, author = {Selmer, Thorsten and Hallmann, Armin and Schmidt, Bernhard and Sumper, Manfred}, title = {The Evolutionary Conservation of a Novel Protein Modification, the Conversion of Cysteine to Serinesemialdehyde in Arylsulfatase from Volvox carteri / Selmer, Thorsten ; Hallmann, Armin ; Schmidt, Bernhard ; Sumper, Manfred ; Figura, Kurt von}, series = {European Journal of Biochemistry. 238 (1996), H. 2}, journal = {European Journal of Biochemistry. 238 (1996), H. 2}, isbn = {0014-2956}, pages = {341 -- 345}, year = {1996}, language = {en} } @article{PolenKraemerBongaertsetal.2005, author = {Polen, T. and Kr{\"a}mer, Marco and Bongaerts, Johannes and Wubbolts, Marcel and Wendisch, V. F.}, title = {The global gene expression response of Escherichia coli to L-phenylalanine}, series = {Journal of biotechnology}, volume = {Vol. 115}, journal = {Journal of biotechnology}, number = {Iss. 3}, issn = {1873-4863 (E-Journal); 0168-1656 (Print)}, pages = {221 -- 237}, year = {2005}, language = {en} } @article{GlaserLubitzLovelandetal.2009, author = {Glaser, Stefan and Lubitz, Sandra and Loveland, Kate L. and Ohbo, Kazu and Robb, Lorraine and Schwenk, Frieder and Seibler, Jost and Roellig, Daniela and Kranz, Andrea and Anastassiadis, Konstantinos and Stewart, A. Francis}, title = {The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis}, series = {Epigenetics \& Chromatin}, volume = {2}, journal = {Epigenetics \& Chromatin}, number = {5}, issn = {1756-8935}, doi = {10.1186/1756-8935-2-5}, pages = {1 -- 16}, year = {2009}, language = {en} } @article{SchererBruechleSchaedeletal.1988, author = {Scherer, Ulrich W. and Br{\"u}chle, W. and Sch{\"a}del, M. and Kratz, J. V.}, title = {The Hydration Enthalpies of Md3+ and Lr3+ / W. Br{\"u}chle, M. Sch{\"a}del, U.W. Scherer, J.V. Kratz, K.E. Gregorich, D. Lee, M. Nurmia, R.M. Chasteler, H.L. Hall, R.A. Henderson, D.C. Hoffman}, series = {Inorganica Chimica Acta. 146 (1988), H. 2}, journal = {Inorganica Chimica Acta. 146 (1988), H. 2}, isbn = {0020-1693}, pages = {267 -- 276}, year = {1988}, language = {en} } @article{BiselliThoemmesGaetgensetal.1993, author = {Biselli, Manfred and Th{\"o}mmes, J. and G{\"a}tgens, J. and Runstadler, P. W.}, title = {The influence of dissolved oxygen tension on the metabolic activity of an immobilized hybridoma population / Th{\"o}mmes, J. ; G{\"a}tgens, J. ; Biselli, M. ; Runstadler, P.W. ; Wandrey, C.}, series = {Cytotechnology . 13 (1993), H. 1}, journal = {Cytotechnology . 13 (1993), H. 1}, isbn = {0920-9069}, pages = {29 -- 39}, year = {1993}, language = {en} } @article{KotterRiekert1979, author = {Kotter, Michael and Riekert, L.}, title = {The influence of impregnation, drying and activation on the activity and distribution of CuO on \&\#945;-Alumina}, series = {Preparation of Catalysts II : scientific bases for the preparation of heterogeneous catalysts ; Proceedings of the Second International Symposium, Louvain-la-Neuve, September 4-7, 1978 / Eds.: B. Delmon ... - (Studies in surface science and catalysis ; 3)}, journal = {Preparation of Catalysts II : scientific bases for the preparation of heterogeneous catalysts ; Proceedings of the Second International Symposium, Louvain-la-Neuve, September 4-7, 1978 / Eds.: B. Delmon ... - (Studies in surface science and catalysis ; 3)}, publisher = {Elsevier}, address = {Amsterdam [u.a.]}, isbn = {0-444-41733-8}, pages = {51 -- 63}, year = {1979}, language = {en} } @article{BaumannBrandiniStaubes1994, author = {Baumann, Marcus and Brandini, Frederico and Staubes, Regina}, title = {The influence of light and temperature on carbonspecific DMS release by cultures of Phaeocystis antarctica and three antarctic diatoms / Baumann, Marcus E.M. ; Brandini, Frederico ; Staubes, Regina}, series = {Marine Chemistry. 45 (1994), H. 1-2}, journal = {Marine Chemistry. 45 (1994), H. 1-2}, isbn = {0304-4203}, pages = {129 -- 136}, year = {1994}, language = {en} } @article{LauthSolomunHirschwaldetal.1989, author = {Lauth, Jakob and Solomun, T. and Hirschwald, W. and Christmann, K.}, title = {The interaction of carbon monoxide with a ruthenium(1010) surface}, series = {Surface Science. 210 (1989), H. 1-2}, journal = {Surface Science. 210 (1989), H. 1-2}, isbn = {0039-6028}, pages = {201 -- 224}, year = {1989}, language = {en} } @article{LauthSolomunHirschwaldetal.1989, author = {Lauth, Jakob and Solomun, T. and Hirschwald, W. and Christmann, K.}, title = {The interaction of carbon monoxide with a ruthenium(1010) surface}, series = {Surface Science Letters. 210 (1989), H. 1-2}, journal = {Surface Science Letters. 210 (1989), H. 1-2}, isbn = {0167-2584}, pages = {A74 -- A75}, year = {1989}, language = {en} } @article{BaumannGoeyensTregueretal.1995, author = {Baumann, Marcus and Goeyens, L. and Tr{\´e}guer, P. and Baeyens, W.}, title = {The leading role of ammonium in the nitrogen uptake regime of Southern Ocean marginal ice zones / Goeyens, L. ; Tr{\´e}guer, P. ; Baumann, M.E.M. ; Baeyens, W. ; Dehairs, F.}, series = {Journal of Marine Systems. 6 (1995), H. 4}, journal = {Journal of Marine Systems. 6 (1995), H. 4}, isbn = {0924-7963}, pages = {345 -- 361}, year = {1995}, language = {de} } @article{BaumannRousseauVaulotetal.1994, author = {Baumann, Marcus and Rousseau, V. and Vaulot, D. and Casotti, R.}, title = {The life cycle of Phaeocystis (Prymnesiophycae): evidence and hypotheses / Rousseau, V. ; Vaulot, D. ; Casotti, R. ; Cariou, V. ; Lenz, J. ; Gunkel, J. ; Baumann, M.}, series = {Journal of Marine Systems. 5 (1994), H. 1}, journal = {Journal of Marine Systems. 5 (1994), H. 1}, isbn = {0924-7963}, pages = {23 -- 39}, year = {1994}, language = {en} } @article{SchererHessbergerGaeggeleretal.1989, author = {Scherer, Ulrich W. and Heßberger, F. P. and G{\"a}ggeler, H. W. and Armbruster, P.}, title = {The New Nuclide 225U / F.P. Heßberger, H. G{\"a}ggeler, P. Armbruster, W. Br{\"u}chle, H. Folger, S. Hofmann, D. Jost, J.V. Kratz, M.E. Leino, G. M{\"u}nzenberg, V. Ninov, M. Sch{\"a}del, U.W. Scherer, K. S{\"u}mmerer, A. T{\"u}rler, D. Ackerman}, series = {Zeitschrift f{\"u}r Physik A Hadrons and Nuclei. 333 (1989), H. 1}, journal = {Zeitschrift f{\"u}r Physik A Hadrons and Nuclei. 333 (1989), H. 1}, isbn = {0939-7922}, pages = {111 -- 112}, year = {1989}, language = {en} } @article{KotterRiekertWeyland1985, author = {Kotter, Michael and Riekert, Lothar and Weyland, Friedrich}, title = {The performance of base metal oxides on ceramic carriers as catalysts for air pollution control}, series = {International chemical engineering. 25 (1985), H. 3}, journal = {International chemical engineering. 25 (1985), H. 3}, isbn = {0020-6318}, pages = {418 -- 427}, year = {1985}, language = {en} } @article{WilsonDickieSchreiteretal.2018, author = {Wilson, C. E. and Dickie, A. P. and Schreiter, K. and Wehr, R. and Wilson, E. M. and Bial, J. and Scheer, Nico and Wilson, I. D. and Riley, R. J.}, title = {The pharmacokinetics and metabolism of diclofenac in chimeric humanized and murinized FRG mice}, series = {Archives of Toxicology}, volume = {92}, journal = {Archives of Toxicology}, number = {6}, publisher = {Springer}, issn = {1432-0738}, doi = {10.1007/s00204-018-2212-1}, pages = {1953 -- 1967}, year = {2018}, abstract = {The pharmacokinetics of diclofenac were investigated following single oral doses of 10 mg/kg to chimeric liver humanized and murinized FRG and C57BL/6 mice. In addition, the metabolism and excretion were investigated in chimeric liver humanized and murinized FRG mice. Diclofenac reached maximum blood concentrations of 2.43 ± 0.9 µg/mL (n = 3) at 0.25 h post-dose with an AUCinf of 3.67 µg h/mL and an effective half-life of 0.86 h (n = 2). In the murinized animals, maximum blood concentrations were determined as 3.86 ± 2.31 µg/mL at 0.25 h post-dose with an AUCinf of 4.94 ± 2.93 µg h/mL and a half-life of 0.52 ± 0.03 h (n = 3). In C57BL/6J mice, mean peak blood concentrations of 2.31 ± 0.53 µg/mL were seen 0.25 h post-dose with a mean AUCinf of 2.10 ± 0.49 µg h/mL and a half-life of 0.51 ± 0.49 h (n = 3). Analysis of blood indicated only trace quantities of drug-related material in chimeric humanized and murinized FRG mice. Metabolic profiling of urine, bile and faecal extracts revealed a complex pattern of metabolites for both humanized and murinized animals with, in addition to unchanged parent drug, a variety of hydroxylated and conjugated metabolites detected. The profiles in humanized mice were different to those of both murinized and wild-type animals, e.g., a higher proportion of the dose was detected in the form of acyl glucuronide metabolites and much reduced amounts as taurine conjugates. Comparison of the metabolic profiles obtained from the present study with previously published data from C57BL/6J mice and humans revealed a greater, though not complete, match between chimeric humanized mice and humans, such that the liver humanized FRG model may represent a model for assessing the biotransformation of such compounds in humans.}, language = {en} } @article{WilsonWilsonScheeretal.2017, author = {Wilson, Ian D. and Wilson, Claire E. and Scheer, Nico and Dickie, A.P. and Schreiter, K. and Wilson, E. M. and Riley, R. J. and Wehr, R. and Bial, J.}, title = {The Pharmacokinetics and Metabolism of Lumiracoxib in Chimeric Humanized and Murinized FRG Mice}, series = {Biochemical pharmacology}, volume = {Volume 135}, journal = {Biochemical pharmacology}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-2968}, doi = {10.1016/j.bcp.2017.03.015}, pages = {139 -- 150}, year = {2017}, language = {en} } @article{PrielmeierLangSpeedyetal.1988, author = {Prielmeier, Franz and Lang, E. W. and Speedy, R. J. and L{\"u}demann, H.-D.}, title = {The pressure Dependence of Self Diffusion in Supercooled Light and Heavy Water / F.X. Prielmeier, E .W. Lang, R. J. Speedy, H.-D. L{\"u}demann}, series = {Berichte der Bunsen-Gesellschaft f{\"u}r Physikalische Chemie. 92 (1988)}, journal = {Berichte der Bunsen-Gesellschaft f{\"u}r Physikalische Chemie. 92 (1988)}, isbn = {0005-9021}, pages = {1111}, year = {1988}, language = {en} } @article{VoigtSchroeterJuergenetal.2013, author = {Voigt, Birgit and Schroeter, Rebecca and J{\"u}rgen, Britta and Albrecht, Dirk and Evers, Stefan and Bongaerts, Johannes and Maurer, Karl-Heinz and Schweder, Thomas and Hecker, Michael}, title = {The response of Bacillus licheniformis to heat and ethanol stress and the role of the SigB regulon}, series = {Proteomics}, volume = {Vol. 13}, journal = {Proteomics}, number = {Iss. 14}, publisher = {Wiley}, address = {Weinheim}, issn = {1615-9861 (E-Journal); 1615-9853 (Print)}, pages = {2140 -- 2146}, year = {2013}, language = {en} } @article{PaulssenLengkeekLeetal.2016, author = {Paulßen, Elisabeth and Lengkeek, Nigel A. and Le, Van So and Pellegrini, Paul A. and Greguric, Ivan and Weiner, Ron}, title = {The role of additives in moderating the influence of Fe(III) and Cu(II) on the radiochemical yield of [⁶⁸Ga(DOTATATE)]}, series = {Applied Radiation and Isotopes}, volume = {107}, journal = {Applied Radiation and Isotopes}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1872-9800}, doi = {10.1016/j.apradiso.2015.09.008}, pages = {13 -- 16}, year = {2016}, abstract = {[⁶⁸Ga(DOTATATE)] has demonstrated its clinical usefulness. Both Fe³⁺ and Cu²⁺, potential contaminants in Gallium-68 generator eluent, substantially reduce the radiochemical (RC) yield of [⁶⁸Ga(DOTATATE)] if the metal/ligand ratio of 1:1 is exceeded. A variety of compounds were examined for their potential ability to reduce this effect. Most had no effect on RC yield. However, addition of phosphate diminished the influence of Fe³⁺ by likely forming an insoluble iron salt. Addition of ascorbic acid reduced Cu²⁺ and Fe³⁺ to Cu⁺ and Fe²⁺ respectively, both of which have limited impact on RC yields. At low ligand amounts (5 nmol DOTATATE), the addition of 30 nmol phosphate (0.19 mM) increased the tolerance of Fe3⁺ from 4 nmol to 10 nmol (0.06 mM), while the addition of ascorbic acid allowed high RC yields (>95\%) in the presence of 40 nmol Fe³⁺ (0.25 mM) and 100 nmol Cu²⁺ (0.63 mM). The effect of ascorbic acid was highly pH-dependant, and gave optimal results at pH 3.}, language = {en} } @article{DemmerChowdhurySelmeretal.2017, author = {Demmer, Julius K. and Chowdhury, Nilanjan Pal and Selmer, Thorsten and Ermler, Ulrich and Buckel, Wolfgang}, title = {The semiquinone swing in the bifurcating electron transferring flavoprotein/butyryl-CoA dehydrogenase complex from Clostridium difficile}, series = {Nature Communications}, volume = {8}, journal = {Nature Communications}, number = {1}, issn = {2041-1723}, doi = {10.1038/s41467-017-01746-3}, pages = {1 -- 10}, year = {2017}, language = {en} } @article{BaumannLancelotBrandinietal.1994, author = {Baumann, Marcus and Lancelot, C. and Brandini, F. and Sakshaug, E.}, title = {The taxonomic identity of the cosmopolitan prymnesiophyte Phaeocystis, a morphological and ecophysiological approach / Baumann, M.E.M. ; Lancelot, C. ; Brandini, F. ; Sakshaug, E. ; John M.}, series = {Journal of Marine Systems. 5 (1994), H. 1}, journal = {Journal of Marine Systems. 5 (1994), H. 1}, isbn = {0924-7963}, pages = {5 -- 22}, year = {1994}, language = {en} }