@article{ScheerRossKapelyukhetal.2010, author = {Scheer, Nico and Ross, Jillian and Kapelyukh, Yury and Rode, Anja and Wolf, C. Roland}, title = {In vivo responses of the human and murine pregnane X receptor to dexamethasone in mice}, series = {Drug Metabolism and Disposition}, volume = {38}, journal = {Drug Metabolism and Disposition}, number = {7}, publisher = {ASPET}, address = {Bethesda}, issn = {1521-009X}, doi = {10.1124/dmd.109.031872}, pages = {1046 -- 1053}, year = {2010}, abstract = {Dexamethasone (DEX) is a potent and widely used anti-inflammatory and immunosuppressant glucocorticoid. It can bind and activate the pregnane X receptor (PXR), which plays a critical role as xenobiotic sensor in mammals to induce the expression of many enzymes, including cytochromes P450 in the CYP3A family. This induction results in its own metabolism. We have used a series of transgenic mouse lines, including a novel, improved humanized PXR line, to compare the induction profile of PXR-regulated drug-metabolizing enzymes after DEX administration, as well as looking at hepatic responses to rifampicin (RIF). The new humanized PXR model has uncovered further intriguing differences between the human and mouse receptors in that RIF only induced Cyp2b10 in the new humanized model. DEX was found to be a much more potent inducer of Cyp3a proteins in wild-type mice than in mice humanized for PXR. To assess whether PXR is involved in the detoxification of DEX in the liver, we analyzed the consequences of high doses of the glucocorticoid on hepatotoxicity on different PXR genetic backgrounds. We also studied these effects in an additional mouse model in which functional mouse Cyp3a genes have been deleted. These strains exhibited different sensitivities to DEX, indicating a protective role of the PXR and CYP3A proteins against the hepatotoxicity of this compound.}, language = {en} } @article{Digel2010, author = {Digel, Ilya}, title = {In-situ biological decontamination of an ice melting probe}, year = {2010}, language = {en} } @inproceedings{GoemmelFrauenrathOttenetal.2010, author = {G{\"o}mmel, Andreas and Frauenrath, Tobias and Otten, Mario and Niendorf, Thoralf and Butenweg, Christoph}, title = {In-vivo measurements of vocal fold geometry using Magnetic Resonance Imaging}, series = {Fortschritte der Akustik - DAGA 2010 36. Jahrestagung f{\"u}r Akustik, 15. bis 18. M{\"a}rz 2010 in Berlin}, booktitle = {Fortschritte der Akustik - DAGA 2010 36. Jahrestagung f{\"u}r Akustik, 15. bis 18. M{\"a}rz 2010 in Berlin}, editor = {M{\"o}ser, Michael and Schulte-Fortkamp, Brgitte and Ochmann, Martin}, publisher = {Deutsche Gesellschaft f{\"u}r Akustik}, address = {Berlin}, isbn = {978-3-9808659-8-2}, year = {2010}, language = {de} } @article{HeinzelSchaeferMuelleretal.2010, author = {Heinzel, Alexander and Sch{\"a}fer, Ralf and M{\"u}ller, Hans-Wilhelm and Schieffer, Andre and Ingenhag, Ariane and Eickhoff, Simon B. and Northoff, Georg and Franz, Matthias and Hautzel, Hubertus}, title = {Increased Activation of the Supragenual Anterior Cingulate Cortex during Visual Emotional Processing in Male Subjects with High Degrees of Alexithymia: An Event-Related fMRI Study}, series = {Psychotherapy and Psychosomatics}, volume = {79}, journal = {Psychotherapy and Psychosomatics}, number = {6}, publisher = {Karger}, address = {Basel}, issn = {0033-3190}, doi = {10.1159/000320121}, pages = {363 -- 370}, year = {2010}, abstract = {Background: One of the most prominent neurobiological models of alexithymia assumes an altered function of the anterior cingulate cortex (ACC) as the crucial neural correlate of alexithymia. So far functional imaging studies have yielded inconclusive results. Therefore, we tested this hypothesis in healthy alexithymics and nonalexithymics in an event-related fMRI study. Methods: Thirty high- and 30 low-alexithymic right-handed male subjects (selected by the 20-item Toronto Alexithymia Scale, TAS-20) were investigated with event-related fMRI using a picture viewing paradigm. The stimuli consisted of happy, fearful and neutral facial expressions (Ekman-Friesen) as well as positive, negative and neutral pictures from the International Affective Picture System. Results: Contrasting the high-alexithymic with the low-alexithymic group we observed increased activation of the supragenual ACC for different emotional valences as well as for different emotional stimuli. Moreover, there was a positive correlation of the ACC with the individual TAS-20 scores but no correlations with the individual Beck Depression Inventory scores. Additionally, there was no difference in activity of the amygdala. Conclusions: We demonstrated that the supragenual ACC is constantly activated more strongly in alexithymic subjects and that this activation is related to the symptoms of alexithymia and not to associated symptoms such as depression. Therefore, our findings support the hypothesis of an altered function of the ACC in alexithymia.}, language = {en} } @phdthesis{Albracht2010, author = {Albracht, Kirsten}, title = {Influence of mechanical properties of the leg extensor muscletendon units on running economy}, publisher = {Deutsche Sporthochschule K{\"o}ln}, address = {K{\"o}ln}, pages = {X, 1221 Bl. : graph. Darst.}, year = {2010}, language = {en} } @book{OPUS4-4303, title = {Ingenieurfreunde FH Aachen : 75 Jahre F{\"o}rderverein; Elektrotechnik und Informationstechnik, Luft- und Raumfahrttechnik, Maschinenbau und Mechatronik / [Hrsg.: Ingenieurfreunde FH Aachen e. V. ; Red.: H. J. Raatschen]}, editor = {Raatschen, Hans-J{\"u}rgen}, publisher = {Klinkenberg}, address = {Aachen}, isbn = {978-3-941704-03-9}, pages = {112 S. : Ill., graph. Darst.}, year = {2010}, language = {de} } @book{MeinhardtKernKauffmannetal.2010, author = {Meinhardt, Stefan and Kern, Christian and Kauffmann, Kristian and Jahraus, Jochen and Lindemann, Markus}, title = {Innovative Gestaltung von Gesch{\"a}ftsprozessen in der Konsumg{\"u}terindustrie : Marktumfeld - Herausforderungen - Vorgehensmodell - Praxisbeispiele - Handlungsempfehlungen / [SAP Consulting] Stefan Meinhardt ... Unter Mitarb. von ... Markus A. Lindemann ...}, publisher = {dpunkt-Verl.}, address = {Heidelberg}, isbn = {978-3-89864-527-0}, pages = {XIV; 232 S. : graph. Darst.}, year = {2010}, language = {de} } @inproceedings{SchuermannLeidingerWollert2010, author = {Sch{\"u}rmann, Volker and Leidinger, Rafael and Wollert, J{\"o}rg}, title = {Intelligent IO-Terminals for complex communication scenarios in control applications}, series = {Proceedings : the 3rd International Multi-Conference on Engineering and Technological Innovation : June 29th - July 2nd, 2010, Orlando, Florida, USA}, booktitle = {Proceedings : the 3rd International Multi-Conference on Engineering and Technological Innovation : June 29th - July 2nd, 2010, Orlando, Florida, USA}, organization = {International Multi-Conference on Engineering and Technological Innovation <3, 2010, Orlando, Fla.>}, pages = {1 -- 5}, year = {2010}, language = {de} } @article{JansenBehbahaniLaumenetal.2010, author = {Jansen, S. V. and Behbahani, Mehdi and Laumen, M. and Kaufmann, T. and Hormes, M. and Behr, M. and Schmitz-Rode, T. and Steinseifer, U.}, title = {Investigation of Steady Flow Through a Realistic Model of the Thoracic Human Aorta Using 3D Stereo PIV and CFD-Simulation}, year = {2010}, language = {en} } @inproceedings{HeinzOertelBung2010, author = {Heinz, G. and Oertel, Mario and Bung, Daniel B.}, title = {Investigations on a cooling water system for a gas tubine facility concerning air vortexes and sediment transport}, series = {Hydraulic structures: useful water harvesting systems or relics? : Third International Junior Researcher and Engineer Workshop on Hydraulic Structures (IJREWHS'10) : Edinburgh, Scotland, U.K., 2-3 May 2010}, booktitle = {Hydraulic structures: useful water harvesting systems or relics? : Third International Junior Researcher and Engineer Workshop on Hydraulic Structures (IJREWHS'10) : Edinburgh, Scotland, U.K., 2-3 May 2010}, editor = {Janssen, Robert}, publisher = {School of Civil Engineering, The University of Queensland}, address = {Brisbane}, organization = {International Junior Researcher and Engineer Workshop on Hydraulic Structures <3, 2010, Edinburgh>}, isbn = {9781742720159}, pages = {109 -- 116}, year = {2010}, language = {en} } @inproceedings{BegingPoghossianMlyneketal.2010, author = {Beging, Stefan and Poghossian, Arshak and Mlynek, D. and Hataihimakul, S. and Pedraza, A. and Dhawan, S. and Laube, N. and Kleinen, L. and Baldsiefen, G. and Busch, H. and Sch{\"o}ning, Michael Josef}, title = {Ion-selective sensors for the determination of the risk of urinary stone formation}, series = {Micro- and Nanosystems in biochemical diagnosis : Principles and applications}, booktitle = {Micro- and Nanosystems in biochemical diagnosis : Principles and applications}, address = {Warsaw}, pages = {74 -- 80}, year = {2010}, language = {en} } @article{EgliAyerPeteretal.2010, author = {Egli, Simon and Ayer, Fran{\c{c}}ois and Peter, Martina and Eilmann, Britta and Rigling, Andreas}, title = {Is forest mushroom productivity driven by tree growth? Results from a thinning experiment}, series = {Annals of Forest Science}, volume = {67}, journal = {Annals of Forest Science}, number = {5}, publisher = {Springer}, address = {Paris}, issn = {1286-4560 (Print)}, doi = {10.1051/forest/2010011}, pages = {509}, year = {2010}, abstract = {• Most of the edible forest mushrooms are mycorrhizal and depend on carbohydrates produced by the associated trees. Fruiting patterns of these fungi are not yet fully understood since climatic factors alone do not completely explain mushroom occurrence. • The objective of this study was to retrospectively find out if changing tree growth following an increment thinning has influenced the diversity patterns and productivity of associated forest mushrooms in the fungus reserve La Chan{\´e}az, Switzerland. • The results reveal a clear temporal relationship between the thinning, the growth reaction of trees and the reaction of the fungal community, especially for the ectomycorrhizal species. The tree-ring width of the formerly suppressed beech trees and the fruit body number increased after thinning, leading to a significantly positive correlation between fruit body numbers and tree-ring width. • Fruit body production was influenced by previous annual tree growth, the best accordance was found between fruit body production and the tree-ring width two years previously. • The results support the hypothesis that ectomycorrhizal fruit body production must be linked with the growth of the associated host trees. Moreover, the findings indicate the importance of including mycorrhizal fungi as important players when discussing a tree as a carbon source or sink.}, language = {en} } @inproceedings{AbelBoninAlbrachtetal.2010, author = {Abel, Thomas and Bonin, Dominik and Albracht, Kirsten and Zeller, Sebastian and Br{\"u}ggemann, Gert-Peter and Burkett, Brendan and Str{\"u}der, Heiko K.}, title = {Kinematic profile of the elite handcyclist}, series = {28th International Conference on Biomechanics in Sports, Marquette, Michigan, USA, July 19 - 23, 2010}, booktitle = {28th International Conference on Biomechanics in Sports, Marquette, Michigan, USA, July 19 - 23, 2010}, issn = {1999-4168}, pages = {140 -- 141}, year = {2010}, language = {en} } @book{OPUS4-5166, title = {Kinetische Leuchtskulpturen : ein Projekt des Fachbereichs Gestaltung an der FH Aachen in Zusammenarbeit mit dem Rotary Club Aachen-Charlemagne}, publisher = {FH Aachen}, address = {Aachen}, pages = {32 S. : zahlr. Ill.}, year = {2010}, language = {de} } @incollection{ReisgenSchleserStieglitz2010, author = {Reisgen, Uwe and Schleser, Markus and Stieglitz, Anja}, title = {Kleben in anspruchsvollen Anwendungsbereichen}, series = {Jahrbuch Schweißtechnik 2011}, booktitle = {Jahrbuch Schweißtechnik 2011}, publisher = {DVS}, address = {D{\"u}sseldorf}, isbn = {0935-0292}, pages = {226 -- 235}, year = {2010}, language = {de} } @article{HoffmannSchermutzkiWinckelmannSchlieper2010, author = {Hoffmann, Ulrich and Schermutzki, Margret and Winckelmann-Schlieper, Katja}, title = {Kompetenzbasierte Verzahnung von berufspraktischem und wissenschaftlichem Lernen : Der Studiengang Prozesstechnik der FH Aachen}, series = {Berufsbildung in Wissenschaft und Praxis (BWP). 39 (2010), H. 2}, journal = {Berufsbildung in Wissenschaft und Praxis (BWP). 39 (2010), H. 2}, isbn = {0341-4515}, pages = {32 -- 36}, year = {2010}, language = {de} } @inproceedings{ReisgenSchleserHarmsetal.2010, author = {Reisgen, Uwe and Schleser, Markus and Harms, Alexander and Schiebahn, Alexander}, title = {Konduktiv unterst{\"u}tztes R{\"u}hrreibschweißen an Stahl- und Aluminiumwerkstoffen}, series = {DVS congress 2010 : Große Schweißtechnische Tagung ; Studentenkongress ; Statusseminar "Schneidtechnik" ; Abschlusskolloquium zum AiF-Forschungscluster "Integration des R{\"u}hrreibschweißens in Fertigungsprozessketten" ; Vortr{\"a}ge der Veranstaltung in N{\"u}rnberg am 27. und 28. September 2010. (DVS-Berichte ; 267)}, booktitle = {DVS congress 2010 : Große Schweißtechnische Tagung ; Studentenkongress ; Statusseminar "Schneidtechnik" ; Abschlusskolloquium zum AiF-Forschungscluster "Integration des R{\"u}hrreibschweißens in Fertigungsprozessketten" ; Vortr{\"a}ge der Veranstaltung in N{\"u}rnberg am 27. und 28. September 2010. (DVS-Berichte ; 267)}, publisher = {DVS Media}, address = {D{\"u}sseldorf}, organization = {Deutscher Verband f{\"u}r Schweißen und Verwandte Verfahren ; Große Schweißtechnische Tagung <2010, N{\"u}rnberg>}, isbn = {978-3-87155-592-3}, pages = {394 -- 398}, year = {2010}, language = {de} } @book{HeuermannSimonIbrahim2010, author = {Heuermann, Holger and Simon, Sven and Ibrahim, Irfan}, title = {Konzeption und Realisierung eines spektralreinen vektoriellen Transmitters mit CMOS-Sigma-Delta-Synthesizern im 1-5 GHz-Bereich / Antragsteller: Fachhochschule Aachen ... Teilprojektleitung: Heuermann}, publisher = {Fachhochschule}, address = {Aachen}, pages = {156 S. : Ill., graph. Darst.}, year = {2010}, language = {de} } @book{Matcha2010, author = {Matcha, Heike}, title = {Konzerthaus in Stralsund : Masterentwurf SS 2009}, publisher = {Technische Universit{\"a}t Darmstadt}, address = {Darmstadt}, isbn = {978-3-88536-114-5}, pages = {83 S. : {\"u}berw. Ill.}, year = {2010}, language = {de} } @article{Olbertz2010, author = {Olbertz, Klaus}, title = {Kurzarbeit und betriebsbedingte K{\"u}ndigungen - Wissenswertes f{\"u}r die betriebliche Praxis}, series = {NWB - Steuer- und Wirtschaftsrecht}, journal = {NWB - Steuer- und Wirtschaftsrecht}, number = {37}, publisher = {NWB-Verlag}, address = {Herne}, issn = {1860-9449}, pages = {2966 -- 2972}, year = {2010}, abstract = {Kurzarbeit war und ist eines der wesentlichen Elemente der Unternehmen, um dem durch die Finanz- und Wirtschaftskrise begr{\"u}ndeten Arbeitskr{\"a}fte{\"u}berhang begegnen zu k{\"o}nnen. Laut statistischer Mitteilung der Bundesagentur f{\"u}r Arbeit waren im Mai 2009 ca. 1,52 Mio. Arbeitnehmer in Kurzarbeit, im M{\"a}rz 2010 waren es immer noch 830.000 Arbeitnehmer, die Kurzarbeitergeld bezogen haben. Bis Ende 2010 k{\"o}nnen Arbeitgeber Kurzarbeit noch f{\"u}r die verl{\"a}ngerte H{\"o}chstbezugsdauer von bis zu 18 Monaten beantragen. Zudem hat der Bundestag am 8.7.2010 eine nochmalige Verl{\"a}ngerung der Erstattung der Sozialversicherungsbeitr{\"a}ge bis M{\"a}rz 2012 verabschiedet. Trotzdem m{\"u}ssen zahlreiche Arbeitgeber inzwischen feststellen, dass sie allein mit dem Mittel der Kurzarbeit nicht um einen Personalabbau herumkommen. Dies gilt insbesondere f{\"u}r diejenigen Unternehmen, die gleich zu Beginn der Krise im Herbst 2008 Kurzarbeit eingef{\"u}hrt haben und bei denen deshalb die damals noch geltende 24-monatige H{\"o}chstbezugsdauer im Herbst 2010 auslaufen wird}, language = {de} }