@article{AkimbekovZhubanovaMansurovetal.2010,
  author    = {Akimbekov, Nuraly S. and Zhubanova, A. A. and Mansurov, Z. A. and Digel, Ilya and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l},
  title     = {Use of Carbonized Rise Shell for the local treatment of wounds},
  series = {Eurasian ChemTech Journal},
  volume    = {12},
  journal   = {Eurasian ChemTech Journal},
  number    = {2},
  publisher = {Institute of Combustion Problems},
  address   = {Almaty},
  issn      = {2522-4867},
  doi       = {10.18321/ectj35},
  pages     = {133 -- 138},
  year      = {2010},
  abstract  = {On the model of musculocutaneous wound in rats, the effect of applicative sorption by carbonized rise shell (CRS) on the healing of festering wound was studied. It has been shown, that cytological changes end with rapid scar formation. The use of CRS at the period of severe purulent wound contributes to its favorable course, prevents the development of complications of the animals from sepsis.},
  language  = {en}
}
@article{SiqueiraMakiPaulovichetal.2010,
  author    = {Siqueira, Jose R. and Maki, Rafael M. and Paulovich, Fernando V. and Werner, Frederik and Poghossian, Arshak and Oliveira, Maria C. F. de and Zucolotto, Valtencir and Oliveira, Osvaldo N. Jr. and Sch{\"o}ning, Michael Josef},
  title     = {Use of Information Visualization Methods Eliminating Cross Talk in Multiple Sensing Units Investigated for a Light-Addressable Potentiometric Sensor},
  series = {Analytical Chemistry (2010)},
  journal   = {Analytical Chemistry (2010)},
  isbn      = {0003-2700},
  pages     = {61 -- 65},
  year      = {2010},
  language  = {en}
}
@article{GarhoferBekBoehmetal.2010,
  author    = {Garhofer, Gerhard and Bek, Toke and Boehm, Andreas G. and Gherghel, Doina and Grundwald, Juan and Jeppesen, Peter and Kergoat, H{\´e}l{\`e}ne and Kotliar, Konstantin and Lanzl, Ines and Lovasik, John V. and Nagel, Edgar and Vilser, Walthard and Orgul, Selim and Schmetterer, Leopold},
  title     = {Use of the retinal vessel analyzer in ocular blood flow research},
  series = {Acta Ophthalmol},
  volume    = {88},
  journal   = {Acta Ophthalmol},
  number    = {7},
  publisher = {Wiley-Blackwell},
  address   = {Oxford},
  issn      = {1755-3768},
  doi       = {10.1111/j.1755-3768.2009.01587.x},
  pages     = {717 -- 722},
  year      = {2010},
  abstract  = {The present article describes a standard instrument for the continuous online determination of retinal vessel diameters, the commercially available retinal vessel analyzer. This report is intended to provide informed guidelines for measuring ocular blood flow with this system. The report describes the principles underlying the method and the instruments currently available, and discusses clinical protocol and the specific parameters measured by the system. Unresolved questions and the possible limitations of the technique are also discussed.},
  language  = {en}
}
@article{BohrnStuetzFleischeretal.2013,
  author    = {Bohrn, Ulrich and St{\"u}tz, Evamaria and Fleischer, Maximilian and Sch{\"o}ning, Michael Josef and Wagner, Patrick},
  title     = {Using a cell-based gas biosensor for investigation of adverse effects of acetone vapors in vitro},
  series = {Biosensors and Bioelectronics. 40 (2013), H. 1},
  journal   = {Biosensors and Bioelectronics. 40 (2013), H. 1},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {0956-5663},
  pages     = {393 -- 400},
  year      = {2013},
  language  = {en}
}
@inproceedings{SchreiberBarkschatKraft2014,
  author    = {Schreiber, Marc and Barkschat, Kai and Kraft, Bodo},
  title     = {Using Continuous Integration to organize and monitor the annotation process of domain specific corpora},
  series = {5th International Conference on Information and Communication Systems (ICICS) : 1-3 April 2014, Irbid, Jordanien},
  booktitle = {5th International Conference on Information and Communication Systems (ICICS) : 1-3 April 2014, Irbid, Jordanien},
  organization    = {International Conference on Information and Communication Systems <5, 2014, Irbid, Jordanien>},
  isbn      = {978-1-4799-3022-7},
  doi       = {10.1109/IACS.2014.6841958},
  pages     = {1 -- 6},
  year      = {2014},
  language  = {en}
}
@article{ZangeSchopenAlbrachtetal.2017,
  author    = {Zange, Jochen and Schopen, Kathrin and Albracht, Kirsten and Gerlach, Darius A. and Frings-Meuthen, Petra and Maffiuletti, Nicola A. and Bloch, Wilhelm and Rittweger, J{\"o}rn},
  title     = {Using the Hephaistos orthotic device to study countermeasure effectiveness of neuromuscular electrical stimulation and dietary lupin protein supplementation, a randomised controlled trial},
  series = {Plos one},
  volume    = {12},
  journal   = {Plos one},
  number    = {2},
  doi       = {10.1371/journal.pone.0171562},
  year      = {2017},
  language  = {en}
}
@article{WagnerMiyamotoWerneretal.2011,
  author    = {Wagner, Torsten and Miyamoto, K. and Werner, Frederik and Sch{\"o}ning, Michael Josef and Yoshinobu, T.},
  title     = {Utilising Digital Micro-Mirror Device (DMD) as Scanning Light Source for Light-Addressable Potentiometric Sensors (LAPS)},
  volume    = {9},
  number    = {2},
  publisher = {American Scientific Publishers},
  address   = {Stevenson Ranch, Calif.},
  doi       = {10.1166/sl.2011.1620},
  pages     = {812 -- 815},
  year      = {2011},
  language  = {en}
}
@inproceedings{AzarDigel2019,
  author    = {Azar, Fouad and Digel, Ilya},
  title     = {Utilization of fluorescence spectroscopy and neural networks in clinical analysis},
  series = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen},
  booktitle = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen},
  editor    = {Staat, Manfred and Erni, Daniel},
  publisher = {Universit{\"a}t Duisburg-Essen},
  address   = {Duisburg},
  organization    = {MedTech Symposium},
  isbn      = {978-3-940402-22-6},
  doi       = {10.17185/duepublico/48750},
  pages     = {40 -- 41},
  year      = {2019},
  abstract  = {Fluorescence topography of human urine in combination with learning algorithms can provide a variant pattern recognition method in analytical clinical chemistry and, eventually, diagnosis.},
  language  = {en}
}
@article{MuellerHirschfeldLambertzetal.2014,
  author    = {M{\"u}ller, Martin and Hirschfeld, Julian and Lambertz, Rita and Schulze Lohoff, Andreas and Lustfeld, Hans and Pfeifer, Heinz and Reißel, Martin},
  title     = {Validation of a novel method for detecting and stabilizing malfunctioning areas in fuel cell stacks},
  series = {Journal of power sources},
  volume    = {272},
  journal   = {Journal of power sources},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-2755 (E-Journal); 0378-7753 (Print)},
  doi       = {10.1016/j.jpowsour.2014.08.045},
  pages     = {225 -- 232},
  year      = {2014},
  abstract  = {In this paper a setup for detecting malfunctioning areas of MEAs in fuel cell stacks is described. Malfunctioning areas generate electric cross currents inside bipolar plates. To exploit this we suggest bipolar plates consisting not of two but of three layers. The third one is a highly conducting layer and segmented such that the cross currents move along the segments to the surface of the stack where they can be measured by an inductive sensor. With this information a realistic model can be used to detect the malfunctioning area. Furthermore the third layer will prevent any current inhomogeneity of a malfunctioning cell to spread to neighbouring cells in the stack. In this work the results of measurements in a realistic cell setup will be compared with the results obtained in simulation studies with the same configuration. The basis for the comparison is the reliable characterisation of the electrical properties of the cell components and the implication of these results into the simulation model. The experimental studies will also show the limits in the maximum number of segments, which can be used for a reliable detection of cross currents.},
  language  = {en}
}
@article{ZiemonsHeinrichsStreunetal.2004,
  author    = {Ziemons, Karl and Heinrichs, U. and Streun, M. and Pietrzyk, U.},
  title     = {Validation of GEANT3 simulation studies with a dual-head PMT ClearPET™ prototype},
  series = {2003 IEEE Nuclear Science Symposium Conference Record, Vol. 5},
  journal   = {2003 IEEE Nuclear Science Symposium Conference Record, Vol. 5},
  issn      = {1082-3654},
  pages     = {3053 -- 3056},
  year      = {2004},
  abstract  = {The ClearPET™ project is proposed by working groups of the Crystal Clear Collaboration (CCC) to develop a 2nd generation high performance small animal positron emission tomograph (PET). High sensitivity and high spatial resolution is foreseen for the ClearPET™ camera by using a phoswich arrangement combining mixed lutetium yttrium aluminum perovskite (LuYAP:Ce) and lutetium oxyorthosilicate (LSO) scintillating crystals. Design optimizations for the first photomultiplier tube (PMT) based ClearPET camera are done with a Monte-Carlo simulation package implemented on GEANT3 (CERN, Geneva, Switzerland). A dual-head prototype has been built to test the frontend electronics and was used to validate the implementation of the GEANT3 simulation tool. Multiple simulations were performed following the experimental protocols to measure the intrinsic resolution and the sensitivity profile in axial and radial direction. Including a mean energy resolution of about 27.0\% the simulated intrinsic resolution is about (1.41±0.11)mm compared to the measured of (1.48±0.06)mm. The simulated sensitivity profiles show a mean square deviation of 12.6\% in axial direction and 3.6\% in radial direction. Satisfactorily these results are representative for all designs and confirm the scanner geometry.},
  language  = {en}
}
@article{ArtmannTeitelSchmidSchoenbein1987,
  author    = {Artmann, Gerhard and Teitel, P. and Schmid-Sch{\"o}nbein, H.},
  title     = {Variable rheologische Antwort der Erythrozyten auf den Einfluß von Xantinderivaten (Coffein): Experimentelle Differenzierung von "Responders" und "Nonresponders"},
  series = {11. Jahrestagung der Gesellschaft f{\"u}r Mikrozirkulation},
  journal   = {11. Jahrestagung der Gesellschaft f{\"u}r Mikrozirkulation},
  publisher = {Karger [u.a.]},
  address   = {Basel [u.a.]},
  pages     = {100 -- 105},
  year      = {1987},
  language  = {de}
}
@article{KotliarLanzl2018,
  author    = {Kotliar, Konstantin and Lanzl, Ines},
  title     = {Vaskul{\"a}re Biomarker der retinalen Gef{\"a}βanalyse},
  series = {Klinische Monatsbl{\"a}tter fur Augenheilkunde},
  volume    = {235},
  journal   = {Klinische Monatsbl{\"a}tter fur Augenheilkunde},
  number    = {12},
  publisher = {Thieme},
  address   = {Stuttgart},
  issn      = {0023-2165},
  doi       = {10.1055/a-0774-7987},
  pages     = {1352 -- 1359},
  year      = {2018},
  abstract  = {Mit modernen nicht invasiven bildgebenden Verfahren lassen sich anhand der Fundusfotografie bzw. der optischen Verfilmung Aspekte der funktionellen und strukturellen retinalen Gef{\"a}ßver{\"a}nderungen objektiv untersuchen. Der Zustand und das Verhalten retinaler Gef{\"a}ße beeinflussen im pr{\"a}-, post- und kapillaren Bereich den Blutfluss und str{\"o}mungsbedingte Stoffwechselverh{\"a}ltnisse passiv und aktiv {\"u}ber den Gef{\"a}ßdurchmesser. Retinale Gef{\"a}ße gleichen von Aufbau und Funktion den zerebralen Gef{\"a}ßen und spiegeln den Zustand der Mikrozirkulation wider. Mithilfe von aus den Gef{\"a}ßweiten berechneten Biomarkern soll eine Aussage {\"u}ber die Prognose von systemischen vaskul{\"a}r bedingten Erkrankungen getroffen werden. Die statische retinale Gef{\"a}ßanalyse befasst sich mit der Untersuchung des Zustandes der pr{\"a}- und postkapillaren Gef{\"a}ßdurchmesser der retinalen Mikrozirkulation anhand einer optischen Fundusaufnahme. Bei der dynamischen retinalen Gef{\"a}ßanalyse wird der L{\"a}ngsschnitt eines retinalen Gef{\"a}ßes nicht invasiv funktionell und strukturell {\"u}ber einen Zeitraum vor, w{\"a}hrend und nach einer spezifischen vaskul{\"a}ren Stimulation untersucht. Die genaue Methodologie der Auswertung und die Bezeichnung der Parameter variieren bei unterschiedlichen Ans{\"a}tzen. Mittels retinaler Gef{\"a}ßanalyse wurden bislang mehrere klinische Querschnitts- und Interventionsstudien in der Augenheilkunde und anderen Fachgebieten, inkl. Kardiologie, Neurologie, Neurochirurgie, Nephrologie, Gyn{\"a}kologie, Sportmedizin, Diabetologie, Hypertensiologie usw. durchgef{\"u}hrt. Mit der statischen retinalen Gef{\"a}ßanalyse steht eine kosteng{\"u}nstige, reproduzierbare, nicht invasive Screeningtechnik zur Verf{\"u}gung, um eine prognostische Aussage {\"u}ber die Gef{\"a}ßgesundheit eines individuellen Patienten zu treffen. Die dynamische retinale Gef{\"a}ßanalyse besitzt ein weiteres diagnostisches Anwendungsspektrum als die statische, da sie das Verhalten retinaler Gef{\"a}ße zeitkontinuierlich untersucht. Die Evaluation vaskul{\"a}rer Erkrankungen sowie zerebro- bzw. kardiovaskul{\"a}rer Morbidit{\"a}t und Mortalit{\"a}t mittels mehrerer methodologischer Modalit{\"a}ten retinaler Gef{\"a}ßanalyse mit ihren jeweiligen quantitativen Biomarkern bietet eine zukunftstr{\"a}chtige diagnostische Perspektive. Die interdisziplin{\"a}re klinische Anwendung dieser vaskul{\"a}ren Biomarker gewinnt zunehmend an Bedeutung, sowohl in der Augenheilkunde als auch in anderen Fachgebieten.},
  language  = {de}
}
@article{ConzenAlbannaWeissetal.2018,
  author    = {Conzen, Catharina and Albanna, Walid and Weiss, Miriam and K{\"u}rten, David and Vilser, Walthard and Kotliar, Konstantin and Z{\"a}ske, Charlotte and Clusmann, Hans and Schubert, Gerrit Alexander},
  title     = {Vasoconstriction and Impairment of Neurovascular Coupling after Subarachnoid Hemorrhage: a Descriptive Analysis of Retinal Changes},
  series = {Translational Stroke Research},
  journal   = {Translational Stroke Research},
  number    = {9},
  publisher = {Springer Nature},
  address   = {Cham},
  issn      = {1868-601X},
  doi       = {10.1007/s12975-017-0585-8},
  pages     = {284 -- 293},
  year      = {2018},
  abstract  = {Impaired cerebral autoregulation and neurovascular coupling (NVC) contribute to delayed cerebral ischemia after subarachnoid hemorrhage (SAH). Retinal vessel analysis (RVA) allows non-invasive assessment of vessel dimension and NVC hereby demonstrating a predictive value in the context of various neurovascular diseases. Using RVA as a translational approach, we aimed to assess the retinal vessels in patients with SAH. RVA was performed prospectively in 24 patients with acute SAH (group A: day 5-14), in 11 patients 3 months after ictus (group B: day 90 ± 35), and in 35 age-matched healthy controls (group C). Data was acquired using a Retinal Vessel Analyzer (Imedos Systems UG, Jena) for examination of retinal vessel dimension and NVC using flicker-light excitation. Diameter of retinal vessels—central retinal arteriolar and venular equivalent—was significantly reduced in the acute phase (p < 0.001) with gradual improvement in group B (p < 0.05). Arterial NVC of group A was significantly impaired with diminished dilatation (p < 0.001) and reduced area under the curve (p < 0.01) when compared to group C. Group B showed persistent prolonged latency of arterial dilation (p < 0.05). Venous NVC was significantly delayed after SAH compared to group C (A p < 0.001; B p < 0.05). To our knowledge, this is the first clinical study to document retinal vasoconstriction and impairment of NVC in patients with SAH. Using non-invasive RVA as a translational approach, characteristic patterns of compromise were detected for the arterial and venous compartment of the neurovascular unit in a time-dependent fashion. Recruitment will continue to facilitate a correlation analysis with clinical course and outcome.},
  language  = {en}
}
@inproceedings{BlumAlbannaBenninghausetal.2019,
  author    = {Blum, Yannik and Albanna, Walid and Benninghaus, Anne and Kotliar, Konstantin},
  title     = {Vasomotion in retinal vessels of patients presenting post hemorrhagic hydrocephalus following subarachnoid hemorrhage},
  series = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen},
  booktitle = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen},
  editor    = {Staat, Manfred and Erni, Daniel},
  publisher = {Universit{\"a}t Duisburg-Essen},
  address   = {Duisburg},
  organization    = {MedTech Symposium},
  isbn      = {978-3-940402-22-6},
  doi       = {10.17185/duepublico/48750},
  pages     = {38 -- 39},
  year      = {2019},
  abstract  = {Clearance of blood components and fluid drainage play a crucial role in subarachnoid hemorrhage (SAH) and post hemorrhagic hydrocephalus (PHH). With the involvement of interstitial fluid (ISF) and cerebrospinal fluid (CSF), two pathways for the clearance of fluid and solutes in the brain are proposed. Starting at the level of capillaries, flow of ISF follows along the basement membranes in the walls of cerebral arteries out of the parenchyma to drain into the lymphatics and CSF [1]-[3]. Conversely, it is shown that CSF enters the parenchyma between glial and pial basement membranes of penetrating arteries [4]-[6]. Nevertheless, the involved structures and the contribution of either flow pathway to fluid balance between the subarachnoid space and interstitial space remains controversial. Low frequency oscillations in vascular tone are referred to as vasomotion and corresponding vasomotion waves are modeled as the driving force for flow of ISF out of the parenchyma [7]. Retinal vessel analysis (RVA) allows non-invasive measurement of retinal vessel vasomotion with respect to diameter changes [8]. Thus, the aim of the study is to investigate vasomotion in RVA signals of SAH and PHH patients.},
  language  = {en}
}
@article{Weber2001,
  author    = {Weber, Hans-Joachim},
  title     = {Verbundforschungsprojekt Multimediale 3D-Visualisierung der Herzmuskelerregung},
  series = {Intelligente, innovative Produktentwicklung f{\"u}r die industrielle Praxis. Stenzel, Horst [Hrsg.]},
  journal   = {Intelligente, innovative Produktentwicklung f{\"u}r die industrielle Praxis. Stenzel, Horst [Hrsg.]},
  publisher = {Forschungverbund Multimedia an Fachhochschulen},
  address   = {K{\"o}ln},
  pages     = {99 -- 112},
  year      = {2001},
  language  = {de}
}
@misc{BiselliThoemmesWandrey1991,
  author    = {Biselli, Manfred and Th{\"o}mmes, J{\"o}rg and Wandrey, Christian},
  title     = {Verfahren und Vorrichtung zur Abtrennung von Ammonium aus w{\"a}ßrigen Fl{\"u}ssigkeiten [Europ{\"a}ische Patentanmeldung]},
  pages     = {1 -- 12},
  year      = {1991},
  language  = {de}
}
@misc{PapaspyrouBornBisellietal.1996,
  author    = {Papaspyrou, Manfred and Born, Christoph and Biselli, Manfred and Schr{\"o}der, Bernd},
  title     = {Verfahren zur Bestimmung von Pharmakokinetik bzw. Toxikokinetik von Testsubstanzen mit Hilfe von in-vitro-Zellkultursystemen und daf{\"u}r geeignete Vorrichtungen [Offenlegungsschrift]},
  pages     = {1 -- 10},
  year      = {1996},
  language  = {de}
}
@misc{SchmidtJelinekBiselli1999,
  author    = {Schmidt, Sebastian and Jelinek, Nanni and Biselli, Manfred},
  title     = {Verfahren zur Durchf{\"u}hrung von chemischen oder biologischen Reaktionen},
  pages     = {1 -- 12},
  year      = {1999},
  language  = {de}
}
@book{GrafGrossSponagel1988,
  author    = {Graf, G{\"u}nter and Groß, Heinz and Sponagel, Stefan},
  title     = {Verfahren zur Herstellung eines Dichtringes : Europ{\"a}ische Patentschrift EP0250642B1 ; Ver{\"o}ffentlichungstag der Patentschrift: 11.02.1988},
  publisher = {Europ{\"a}isches Patentamt},
  address   = {[M{\"u}nchen u.a.]},
  pages     = {5 S. : Ill.},
  year      = {1988},
  language  = {de}
}
@misc{SponagelGrafGross1987,
  author    = {Sponagel, Stefan and Graf, G{\"u}nter and Groß, Heinz},
  title     = {Verfahren zur Herstellung eines Dichtringes : Patentschrift DE3621242C1 ; Ver{\"o}ffentlichungstag der Patenterteilung : 25.06.1987 / Anmelder: Fa. Carl Freudenberg. Erfinder: G{\"u}nter Graf ; Heinz Groß ; Stefan Sponagel},
  publisher = {Deutsches Patent- und Markenamt},
  address   = {M{\"u}nchen},
  pages     = {5 S. : Ill.},
  year      = {1987},
  language  = {de}
}