@article{BronderPoghossianSchejaetal.2015, author = {Bronder, Thomas and Poghossian, Arshak and Scheja, S. and Wu, Chunsheng and Keusgen, M. and Sch{\"o}ning, Michael Josef}, title = {Electrostatic Detection of Unlabelled Single- and Double-stranded DNA Using Capacitive Field-effect Devices Functionalized with a Positively Charged Polyelectrolyte Layer}, series = {Procedia Engineering}, volume = {120}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2015.08.710}, pages = {544 -- 547}, year = {2015}, abstract = {Capacitive field-effect electrolyte-insulator-semiconductor sensors consisting of an Al-p-Si-SiO2 structure have been used for the electrical detection of unlabelled single- and double-stranded DNA (dsDNA) molecules by their intrinsic charge. A simple functionalization protocol based on the layer-by-layer (LbL) technique was used to prepare a weak polyelectrolyte/probe-DNA bilayer, followed by the hybridization with complementary target DNA molecules. Due to the flat orientation of the LbL-adsorbed DNA molecules, a high sensor signal has been achieved. In addition, direct label-free detection of in-solution hybridized dsDNA molecules has been studied.}, language = {en} } @misc{IngebrandtWagnerSchoening2013, author = {Ingebrandt, Sven and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Engineering of functional interfaces / guest eds. Sven Ingebrandt ; Patrick Wagner ; Michael J. Sch{\"o}ning}, series = {Physica Status Solidi (A)}, volume = {Vol. 210}, journal = {Physica Status Solidi (A)}, number = {Iss. 5}, issn = {1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)}, pages = {845}, year = {2013}, language = {en} } @article{WagnerDollSchoening2014, author = {Wagner, Patrick and Doll, Theodor and Sch{\"o}ning, Michael Josef}, title = {Engineering of functional interfaces / Patrick Wagner ; Theodor Doll ; Michael J. Sch{\"o}ning (eds.)}, series = {Physica status solidi (A) : Applications and materials science}, volume = {211}, journal = {Physica status solidi (A) : Applications and materials science}, number = {6}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1521-396X (E-Book); 1862-6319 (E-Book); 0031-8965 (Print); 1862-6300 (Print)}, doi = {10.1002/pssa.201470241}, pages = {1339 -- 1339}, year = {2014}, language = {en} } @article{DollWagnerWagneretal.2016, author = {Doll, Theodor and Wagner, Torsten and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Engineering of functional interfaces / Theodor Doll ; Torsten Wagner ; Patrick Wagner ; Michael J. Sch{\"o}ning (eds.)}, series = {Physica status solidi (a)}, volume = {213}, journal = {Physica status solidi (a)}, number = {6}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201670641}, pages = {1393 -- 1394}, year = {2016}, language = {en} } @article{MiyamotoSekiWagneretal.2014, author = {Miyamoto, K. and Seki, K. and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, T.}, title = {Enhancement of the spatial resolution of the chemical imaging sensor by a hybrid fiber-optic illumination}, series = {Procedia Engineering}, volume = {87}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2014.11.563}, pages = {612 -- 615}, year = {2014}, abstract = {The chemical imaging sensor, which is based on the principle of the light-addressable potentiometric sensor (LAPS), is a powerful tool to visualize the spatial distribution of chemical species on the sensor surface. The spatial resolution of this sensor depends on the diffusion of photocarriers excited by a modulated light. In this study, a novel hybrid fiber-optic illumination was developed to enhance the spatial resolution. It consists of a modulated light probe to generate a photocurrent signal and a ring of constant light, which suppresses the lateral diffusion of minority carriers excited by the modulated light. It is demonstrated that the spatial resolution was improved from 92 μm to 68 μm.}, language = {en} } @article{NaetherBergerEmmerichetal.2007, author = {N{\"a}ther, Niko and Berger, J{\"o}rg and Emmerich, R{\"u}diger and Friedrich, Peter and Henkel, Hartmut and Schneider, Andreas and Sch{\"o}ning, Michael Josef}, title = {Entwicklung einer kalorimetrischen H2O2-Gassensoranordnung f{\"u}r die Prozessgaskontrolle}, series = {8. Dresdner Sensor-Symposium : Sensoren f{\"u}r Umwelt, Klima und Sicherheit, Biosensoren und Biosysteme, Sensoren und Sensorsysteme f{\"u}r die Prozesstechnik, Trends in der Sensortechnik, Materialentwicklung f{\"u}r die Sensorik; 8. Dresdner Sensor-Symposium, 10. - 12. Dezember 2007, Dresden / Gerald Gerlach ... (Hg.)}, journal = {8. Dresdner Sensor-Symposium : Sensoren f{\"u}r Umwelt, Klima und Sicherheit, Biosensoren und Biosysteme, Sensoren und Sensorsysteme f{\"u}r die Prozesstechnik, Trends in der Sensortechnik, Materialentwicklung f{\"u}r die Sensorik; 8. Dresdner Sensor-Symposium, 10. - 12. Dezember 2007, Dresden / Gerald Gerlach ... (Hg.)}, publisher = {TUDpress, Verl. der Wissenschaften}, address = {Dresden}, isbn = {978-3-940046-45-1}, pages = {261 -- 264}, year = {2007}, language = {de} } @inproceedings{GroebelWernerJoerresetal.2011, author = {Groebel, Simone and Werner, Frederik and J{\"o}rres, Niklas and Jansen, F. and Kasper, Katharina and Schiffels, Johannes and Sprenger, B. and Baumann, Marcus and Sch{\"o}ning, Michael Josef and Selmer, Thorsten}, title = {Entwicklung einer Sensor-{\"U}berwachung f{\"u}r Biogasanlagen auf Basis von Prozessdaten einer Parallelanlage}, series = {10. Dresdner Sensor-Symposium : Dresden, 5. - 7. Dezember 2011 ; miniaturisierte analytische Verfahren, Hochtemperatur-Sensoren, Sensoren f{\"u}r Bioprozess- und Verfahrenstechnik, Sensoren f{\"u}r die Medizin, Chemische Verfahrenstechnik, Lebensmittelanalytik, innovative Sensorl{\"o}sungen, Sensoren f{\"u}r die Wasserqualit{\"a}t, Selbst{\"u}berwachung / Gerald Gerlach ... (Hg.)}, booktitle = {10. Dresdner Sensor-Symposium : Dresden, 5. - 7. Dezember 2011 ; miniaturisierte analytische Verfahren, Hochtemperatur-Sensoren, Sensoren f{\"u}r Bioprozess- und Verfahrenstechnik, Sensoren f{\"u}r die Medizin, Chemische Verfahrenstechnik, Lebensmittelanalytik, innovative Sensorl{\"o}sungen, Sensoren f{\"u}r die Wasserqualit{\"a}t, Selbst{\"u}berwachung / Gerald Gerlach ... (Hg.)}, publisher = {TUDpress}, address = {Dresden}, isbn = {978-3-942710-53-4}, doi = {10.5162/10dss2011/4.3}, pages = {81 -- 84}, year = {2011}, abstract = {Beim Ausbau nachhaltiger, regenerativer Energieversorgung hat die Umwandlung von organischer Biomasse in Biogas ein großes Potential. Der zugrundeliegende, komplexe biologische Prozess wird noch immer unzureichend verstanden und bedarf systematischer Untersuchungen der Prozessparameter, um einen hohen Ertrag bei guter Gasqualit{\"a}t zu erm{\"o}glichen. Die Fragestellungen zur Entschl{\"u}sselung des Prozesses sind sowohl verfahrenstechnischer als auch mikrobiologischer Natur. Aus mikrobiologischer Sicht ist die Kenntnis der tats{\"a}chlich beteiligten prozesstragenden Mikroorganismen von erheblicher Bedeutung, aus verfahrenstechnischer Sicht die Kenntnis der physikalischen und chemischen Faktoren, welche die mikrobiologischen Prozesse und kontrollieren. Im Zusammenspiel aller dieser Parameter wird die Biogasbildung bef{\"o}rdert oder behindert, bis zum Abbruch des Prozesses. Eine m{\"o}gliche Kontrollmethode ist die Messung der metabolischen Aktivit{\"a}t prozesstragender Organismen. Diese soll, beruhend auf fundierten Prozessdaten, gewonnen durch eine Parallelanlage, mit einem lichtadressierbaren potentiometrischen Sensor-System (LAPS) realisiert werden. Dieser Sensor ist in der Lage, pH-Wert-{\"a}nderungen zu detektieren, die durch den Stoffwechsel der auf dem Chip immobilisierten Organismen hervorgerufen werden, um eine Online-{\"U}berwachung von Biogasanlagen zu erm{\"o}glichen.}, language = {de} } @article{BaeckerKowollikSchnitzleretal.2009, author = {B{\"a}cker, Matthias and Kowollik, Silvia and Schnitzler, Thomas and Wang, J. and Poghossian, Arshak and Zang, Werner and Biselli, Manfred and Wagner, P. and Sch{\"o}ning, Michael Josef}, title = {Entwicklung eines festk{\"o}rperbasierten Sensorsystems f{\"u}r die Bioprozessautomatisierung}, series = {9. Dresdner Sensor-Symposium : Dresden, 07.-09. Dezember 2009 / Gerlach, Gerald ; Hauptmann, Peter [Hrsg.]}, journal = {9. Dresdner Sensor-Symposium : Dresden, 07.-09. Dezember 2009 / Gerlach, Gerald ; Hauptmann, Peter [Hrsg.]}, publisher = {TUDpress}, address = {Dresden}, isbn = {978-3-941298-44-6}, pages = {197 -- 200}, year = {2009}, language = {de} } @article{ReisertHenkelSchneideretal.2009, author = {Reisert, Steffen and Henkel, H. and Schneider, A. and Sch{\"a}fer, D. and Friedrich, P. and Berger, J. and Sch{\"o}ning, Michael Josef}, title = {Entwicklung eines Handheld-Sensorsystems f{\"u}r die „On-line"-Messung der H2O2-Konzentration in aseptischen Entkeimungsprozessen}, series = {9. Dresdner Sensor-Symposium : Dresden, 07.-09. Dezember 2009 / Gerlach, Gerald ; Hauptmann, Peter [Hrsg.]}, journal = {9. Dresdner Sensor-Symposium : Dresden, 07.-09. Dezember 2009 / Gerlach, Gerald ; Hauptmann, Peter [Hrsg.]}, publisher = {TUDpress}, address = {Dresden}, isbn = {978-3-941298-44-6}, pages = {285 -- 288}, year = {2009}, language = {de} } @article{BiselliBaeckerPoghossianetal.2010, author = {Biselli, Manfred and B{\"a}cker, Matthias and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Schnitzler, Thomas and Zang, Werner and Wagner, P.}, title = {Entwicklung eines modularen festk{\"o}rperbasierten Sensorsystems f{\"u}r die {\"U}berwachung von Zellkulturfermenationen}, series = {Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vortr{\"a}ge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in N{\"u}rnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA)}, journal = {Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vortr{\"a}ge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in N{\"u}rnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA)}, publisher = {VDE Verlag}, address = {Berlin}, isbn = {978-3-8007-3260-9}, pages = {688 -- 691}, year = {2010}, language = {de} } @article{BaeckerPoghossianSchoeningetal.2010, author = {B{\"a}cker, Matthias and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Schnitzler, Thomas and Biselli, Manfred and Zang, Werner and Wagner, P.}, title = {Entwicklung eines modularen festk{\"o}rperbasierten Sensorsystems f{\"u}r die {\"U}berwachung von Zellkulturfermentationen}, series = {Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vortr{\"a}ge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in N{\"u}rnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA)}, journal = {Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vortr{\"a}ge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in N{\"u}rnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA)}, publisher = {VDE Verlag}, address = {Berlin}, isbn = {978-3-8007-3260-9}, pages = {688 -- 698}, year = {2010}, language = {de} } @article{KeusgenJuengerKnobbeetal.2003, author = {Keusgen, M. and J{\"u}nger, M. and Knobbe, D.-T. and Kloock, Joachim P. and Sch{\"o}ning, Michael Josef}, title = {Entwicklung eines potentiometrischen Cyanid-Biosensors auf der Basis von EIS-Strukturen}, series = {Sensoren f{\"u}r zuk{\"u}nftige Hochtechnologien und Neuentwicklungen f{\"u}r die Verfahrenstechnik / 6. Dresdner Sensor-Symposium, 8. - 10. Dezember 2003, Dresden. J{\"o}rg Peter Baselt; Gerald Gerlach (Hg.)}, journal = {Sensoren f{\"u}r zuk{\"u}nftige Hochtechnologien und Neuentwicklungen f{\"u}r die Verfahrenstechnik / 6. Dresdner Sensor-Symposium, 8. - 10. Dezember 2003, Dresden. J{\"o}rg Peter Baselt; Gerald Gerlach (Hg.)}, publisher = {w.e.b.-Univ.-Verl.}, address = {Dresden}, isbn = {3-935712-92-8}, pages = {235 -- 238}, year = {2003}, language = {de} } @article{SchusserBaeckerKrischeretal.2014, author = {Schusser, Sebastian and B{\"a}cker, Matthias and Krischer, M. and Wenzel, L. and Leinhos, Marcel and Poghossian, Arshak and Biselli, Manfred and Wagner, P. and Sch{\"o}ning, Michael Josef}, title = {Enzymatically catalyzed degradation of biodegradable polymers investigated by means of a semiconductor-based field-effect sensor}, series = {Procedia Engineering}, volume = {87}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2014.11.689}, pages = {1314 -- 1317}, year = {2014}, abstract = {A semiconductor field-effect device has been used for an enzymatically catalyzed degradation of biopolymers for the first time. This novel technique is capable to monitor the degradation process of multiple samples in situ and in real-time. As model system, the degradation of the biopolymer poly(D, L-lactic acid) has been monitored in the degradation medium containing the enzyme lipase from Rhizomucor miehei. The obtained results demonstrate the potential of capacitive field-effect sensors for degradation studies of biodegradable polymers.}, language = {en} } @article{ThustSchoeningSchrothetal.1999, author = {Thust, M. and Sch{\"o}ning, Michael Josef and Schroth, P. and Malkoc, {\"U}. and Dicker, C. I. and Steffen, A. and Kordos, P. and L{\"u}th, H.}, title = {Enzyme immobilisation on planar and porous silicon substrates for biosensor applications}, series = {Journal of Molecular Catalysis B: Enzymatic. 7 (1999), H. 1-4}, journal = {Journal of Molecular Catalysis B: Enzymatic. 7 (1999), H. 1-4}, isbn = {1381-1177}, pages = {77 -- 83}, year = {1999}, language = {en} } @article{PoghossianKatzSchoening2015, author = {Poghossian, Arshak and Katz, Evgeny and Sch{\"o}ning, Michael Josef}, title = {Enzyme logic AND-Reset and OR-Reset gates based on a field-effect electronic transducer modified with multi-enzyme membrane}, series = {Chemical Communications}, volume = {51}, journal = {Chemical Communications}, publisher = {Royal Society of Chemistry (RSC)}, address = {Cambridge}, doi = {10.1039/C5CC01362C}, pages = {6564 -- 6567}, year = {2015}, abstract = {Capacitive field-effect sensors modified with a multi-enzyme membrane have been applied for an electronic transduction of biochemical signals processed by enzyme-based AND-Reset and OR-Reset logic gates. The local pH change at the sensor surface induced by the enzymatic reaction was used for the activation of the Reset function for the first time.}, language = {en} } @incollection{SchoeningPoghossian2018, author = {Sch{\"o}ning, Michael Josef and Poghossian, Arshak}, title = {Enzyme und Biosensorik}, series = {Einf{\"u}hrung in die Enzymtechnologie}, booktitle = {Einf{\"u}hrung in die Enzymtechnologie}, publisher = {Springer Spektrum}, address = {Berlin}, isbn = {978-3-662-57619-9}, doi = {10.1007/978-3-662-57619-9_18}, pages = {323 -- 347}, year = {2018}, abstract = {Enzymbasierte Biosensoren finden seit mehr als f{\"u}nf Jahrzehnten einen prosperierenden Wachstumsmarkt und werden zunehmend auch in biotechnologischen Prozessen eingesetzt. In diesem Kapitel werden, ausgehend vom Sensorbegriff und typischen Kenngr{\"o}ßen f{\"u}r Biosensoren (Abschn. 18.1), elektrochemische Enzym-Biosensoren vorgestellt und deren typischen Einsatzgebiete diskutiert (Abschn. 18.2). Ein Blick {\"u}ber den „Tellerrand" hinaus zeigt alternative Transduktorprinzipien (Abschn. 18.3) und f{\"u}hrt abschließend in aktuelle Forschungstrends ein (Abschn. 18.4).}, language = {de} } @article{KatzPoghossianSchoening2017, author = {Katz, Evgeny and Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Enzyme-based logic gates and circuits - analytical applications and interfacing with electronics}, series = {Analytical and Bioanalytical Chemistry}, volume = {409}, journal = {Analytical and Bioanalytical Chemistry}, publisher = {Springer}, address = {Berlin}, issn = {1618-2650}, doi = {10.1007/s00216-016-0079-7}, pages = {81 -- 94}, year = {2017}, abstract = {The paper is an overview of enzyme-based logic gates and their short circuits, with specific examples of Boolean AND and OR gates, and concatenated logic gates composed of multi-step enzyme-biocatalyzed reactions. Noise formation in the biocatalytic reactions and its decrease by adding a "filter" system, converting convex to sigmoid response function, are discussed. Despite the fact that the enzyme-based logic gates are primarily considered as components of future biomolecular computing systems, their biosensing applications are promising for immediate practical use. Analytical use of the enzyme logic systems in biomedical and forensic applications is discussed and exemplified with the logic analysis of biomarkers of various injuries, e.g., liver injury, and with analysis of biomarkers characteristic of different ethnicity found in blood samples on a crime scene. Interfacing of enzyme logic systems with modified electrodes and semiconductor devices is discussed, giving particular attention to the interfaces functionalized with signal-responsive materials. Future perspectives in the design of the biomolecular logic systems and their applications are discussed in the conclusion.}, language = {en} } @article{TurekKeusgenPoghossianetal.2008, author = {Turek, M. and Keusgen, M. and Poghossian, Arshak and Mulchandani, A. and Wang, J. and Sch{\"o}ning, Michael Josef}, title = {Enzyme-modified electrolyte-insulator-semiconductor sensors}, series = {Journal of Contemporary Physics. 43 (2008), H. 2}, journal = {Journal of Contemporary Physics. 43 (2008), H. 2}, isbn = {1934-9378}, pages = {82 -- 85}, year = {2008}, language = {en} } @article{BandodkarMolinnusMirzaetal.2014, author = {Bandodkar, Amay J. and Molinnus, Denise and Mirza, Omar and Guinovart, Tomas and Windmiller, Joshua R. and Valdes-Ramirez, Gabriela and Andrade, Francisco J. and Sch{\"o}ning, Michael Josef and Wang, Joseph}, title = {Epidermal tattoo potentiometric sodium sensors with wireless signal transduction for continuous non-invasive sweat monitoring}, series = {Biosensors and bioelectronics}, volume = {54}, journal = {Biosensors and bioelectronics}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-4235 (E-Journal); 0956-5663 (Print)}, doi = {10.1016/j.bios.2013.11.039}, pages = {603 -- 609}, year = {2014}, abstract = {This article describes the fabrication, characterization and application of an epidermal temporary-transfer tattoo-based potentiometric sensor, coupled with a miniaturized wearable wireless transceiver, for real-time monitoring of sodium in the human perspiration. Sodium excreted during perspiration is an excellent marker for electrolyte imbalance and provides valuable information regarding an individual's physical and mental wellbeing. The realization of the new skin-worn non-invasive tattoo-like sensing device has been realized by amalgamating several state-of-the-art thick film, laser printing, solid-state potentiometry, fluidics and wireless technologies. The resulting tattoo-based potentiometric sodium sensor displays a rapid near-Nernstian response with negligible carryover effects, and good resiliency against various mechanical deformations experienced by the human epidermis. On-body testing of the tattoo sensor coupled to a wireless transceiver during exercise activity demonstrated its ability to continuously monitor sweat sodium dynamics. The real-time sweat sodium concentration was transmitted wirelessly via a body-worn transceiver from the sodium tattoo sensor to a notebook while the subjects perspired on a stationary cycle. The favorable analytical performance along with the wearable nature of the wireless transceiver makes the new epidermal potentiometric sensing system attractive for continuous monitoring the sodium dynamics in human perspiration during diverse activities relevant to the healthcare, fitness, military, healthcare and skin-care domains.}, language = {en} } @inproceedings{BuniatyanHuckPoghossianetal.2014, author = {Buniatyan, V. V. and Huck, Christina and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Rustamyan, L. G. and Hovnikyan, H. H.}, title = {Equivalent circuit and optimization of impedance characteristics of an electrolyte conductivity sensor}, series = {Proceedings of State Engineering University Armenia : Series Information technologies, electronics, radio engineering}, volume = {Iss. 17}, booktitle = {Proceedings of State Engineering University Armenia : Series Information technologies, electronics, radio engineering}, number = {No. 1}, pages = {69 -- 76}, year = {2014}, language = {en} }