@article{Schoening2002, author = {Sch{\"o}ning, Michael Josef}, title = {Novel approaches to design siliconbased field-effect sensors}, series = {Electrochemical Microsystem Technologies, New Trends in Electrochemistry Vol. 2}, journal = {Electrochemical Microsystem Technologies, New Trends in Electrochemistry Vol. 2}, publisher = {Taylor \& Francis}, address = {London New York}, pages = {384 -- 408}, year = {2002}, language = {en} } @article{HeuermannSadeghfam2004, author = {Heuermann, Holger and Sadeghfam, Arash}, title = {Novel balanced inductor for compact differential systems / Sadeghfam, Arash; Heuermann, Holger}, series = {Conference proceedings : Tuesday 12th, Wednesday 13th and Thursday 14th October, [RAI International Exhibition and Congress Centre, Amsterdam ; part of European Microwave Week 2004] / EuMA, European Microwave Association}, journal = {Conference proceedings : Tuesday 12th, Wednesday 13th and Thursday 14th October, [RAI International Exhibition and Congress Centre, Amsterdam ; part of European Microwave Week 2004] / EuMA, European Microwave Association}, publisher = {Horizon House Publ.}, address = {London}, isbn = {1-580-53992-0}, pages = {709 -- 712}, year = {2004}, language = {en} } @article{BiselliJelinekSchmidtetal.2002, author = {Biselli, Manfred and Jelinek, N. and Schmidt, S. and Hilbert, U.}, title = {Novel bioreactors for the ex vivo cultivation of hematopoietic cells / Jelinek, N. ; Schmidt, S. ; Hilbert, U. ; Thoma, S. ; Biselli, M. ; Wandrey, C.}, series = {Engineering in Life Sciences. 2 (2002), H. 1}, journal = {Engineering in Life Sciences. 2 (2002), H. 1}, isbn = {1618-0240}, pages = {15 -- 18}, year = {2002}, language = {en} } @article{WagnerMiyamotoSchoeningetal.2010, author = {Wagner, Torsten and Miyamoto, Ko-ichiro and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo}, title = {Novel combination of digital light processing (DLP) and light-addressable potentiometric sensors (LAPS) for flexible chemical imaging}, series = {Procedia Engineering. 5 (2010)}, journal = {Procedia Engineering. 5 (2010)}, isbn = {1877-7058}, pages = {520 -- 523}, year = {2010}, language = {en} } @article{HeuermannHillebrandSadeghfam2008, author = {Heuermann, Holger and Hillebrand, J{\"u}rgen and Sadeghfam, Arash}, title = {Novel Concept of a Digital SigmaDelta-PLL-Phase-Shift-Modulator / Hillebrand, J{\"u}rgen ; Sadeghfam, Arash ; Heuermann, Holger}, isbn = {978-3-8007-3086-5}, pages = {123 -- 126}, year = {2008}, language = {en} } @article{PoghossianBerndsenLuethetal.2001, author = {Poghossian, Arshak and Berndsen, Lars and L{\"u}th, Hans and Sch{\"o}ning, Michael Josef}, title = {Novel concepts for flow-rate and flow-direction determination by means of pH-sensitive ISFETs}, series = {Proceedings of SPIE. 4560 (2001)}, journal = {Proceedings of SPIE. 4560 (2001)}, pages = {19 -- 27}, year = {2001}, language = {en} } @article{SchoeningLueth2001, author = {Sch{\"o}ning, Michael Josef and L{\"u}th, H.}, title = {Novel concepts for silicon-based biosensors}, series = {Physica Status Solidi (A) (2001)}, journal = {Physica Status Solidi (A) (2001)}, isbn = {0031-8965}, pages = {65 -- 77}, year = {2001}, language = {en} } @article{SchoeningMalkocThustetal.2000, author = {Sch{\"o}ning, Michael Josef and Malkoc, {\"U}. and Thust, M. and Steffen, A. and Kordos, P. and L{\"u}th, H.}, title = {Novel electrochemical sensors with structured and porous semiconductor/insulator capacitors}, series = {Sensors and Actuators B. 65 (2000), H. 1-3}, journal = {Sensors and Actuators B. 65 (2000), H. 1-3}, isbn = {0925-4005}, pages = {288 -- 290}, year = {2000}, language = {en} } @article{SchoeningMalkocThustetal.1998, author = {Sch{\"o}ning, Michael Josef and Malkoc, {\"U}. and Thust, M. and Steffen, A. and Kordos, P. and L{\"u}th, H.}, title = {Novel electrochemical sensors with structured and porous semiconductor/insulator capacitors}, series = {Proceedings of the Seventh International Meeting on Chemical Sensors : 27 - 30 July, 1998, Beijing, P. R. China / ed. Zhi-Gang Zhou}, journal = {Proceedings of the Seventh International Meeting on Chemical Sensors : 27 - 30 July, 1998, Beijing, P. R. China / ed. Zhi-Gang Zhou}, publisher = {Elsevier}, address = {Amsterdam [u.a.]}, pages = {885 -- 887}, year = {1998}, language = {en} } @article{SelmerJennemannBaueretal.1999, author = {Selmer, Thorsten and Jennemann, Richard and Bauer, Bernhard L. and Bertalanffy, Helmut}, title = {Novel glycoinositolphosphosphingolipids, basidiolipids, from Agaricus / Jennemann, Richard ; Bauer, Bernhard, L. ; Bertalanffy, Helmut ; Geyer, Rudolf ; Gschwind, Ruth, M. ; Selmer, Thorsten ; Wiegandt, Herbert}, series = {European Journal of Biochemistry. 259 (1999), H. 1-2}, journal = {European Journal of Biochemistry. 259 (1999), H. 1-2}, isbn = {0014-2956}, pages = {331 -- 338}, year = {1999}, language = {en} } @article{FoersterLachenmannKastalsky1996, author = {F{\"o}rster, Arnold and Lachenmann, S. G. and Kastalsky, A.}, title = {Novel hybrid Nb/InAs/Nb step junctions / S. G. Lachenmann ; A. Kastalsky ; I. Friedrich ; A. F{\"o}rster ...}, series = {Czechoslovak journal of physics . 46 (1996), H. S2}, journal = {Czechoslovak journal of physics . 46 (1996), H. S2}, isbn = {0011-4626}, pages = {659}, year = {1996}, language = {en} } @article{GuoSekiMiyamotoetal.2014, author = {Guo, Yuanyuan and Seki, Kosuke and Miyamoto, Ko-ichiro and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo}, title = {Novel photoexcitation method for light-addressable potentiometric sensor with higher spatial resolution}, series = {Applied physics express : APEX}, volume = {7}, journal = {Applied physics express : APEX}, number = {6}, publisher = {IOP}, address = {Bristol}, issn = {1882-0786 (E-Journa); 1882-0778 (Print)}, doi = {10.7567/APEX.7.067301}, pages = {067301-4}, year = {2014}, abstract = {A novel photoexcitation method for the light-addressable potentiometric sensor (LAPS) is proposed to achieve a higher spatial resolution of chemical images. The proposed method employs a combined light source that consists of a modulated light probe, which generates the alternating photocurrent signal, and a ring of constant illumination surrounding it. The constant illumination generates a sheath of carriers with increased concentration which suppresses the spread of photocarriers by enhanced recombination. A device simulation was carried out to verify the effect of constant illumination on the spatial resolution, which demonstrated that a higher spatial resolution can be obtained.}, language = {en} } @article{SeilerPichlerPfaffetal.2009, author = {Seiler, Friedrich and Pichler, Alexander and Pfaff, Raphael and Srulijes, Julio}, title = {Novel processing tools for automated doppler picture velocimetry (DPV) evaluation}, series = {Journal of visualization}, volume = {Vol. 12}, journal = {Journal of visualization}, number = {Iss. 4}, issn = {1343-8875}, pages = {323 -- 337}, year = {2009}, language = {en} } @article{HaegerJolmesOyenetal.2024, author = {Haeger, Gerrit and Jolmes, Tristan and Oyen, Sven and Jaeger, Karl-Erich and Bongaerts, Johannes and Sch{\"o}rken, Ulrich and Siegert, Petra}, title = {Novel recombinant aminoacylase from Paraburkholderia monticola capable of N-acyl-amino acid synthesis}, series = {Applied Microbiology and Biotechnology}, journal = {Applied Microbiology and Biotechnology}, number = {108}, publisher = {Springer}, address = {Berlin}, issn = {1432-0614}, doi = {10.1007/s00253-023-12868-8}, pages = {14 Seiten}, year = {2024}, abstract = {N-Acyl-amino acids can act as mild biobased surfactants, which are used, e.g., in baby shampoos. However, their chemical synthesis needs acyl chlorides and does not meet sustainability criteria. Thus, the identification of biocatalysts to develop greener synthesis routes is desirable. We describe a novel aminoacylase from Paraburkholderia monticola DSM 100849 (PmAcy) which was identified, cloned, and evaluated for its N-acyl-amino acid synthesis potential. Soluble protein was obtained by expression in lactose autoinduction medium and co-expression of molecular chaperones GroEL/S. Strep-tag affinity purification enriched the enzyme 16-fold and yielded 15 mg pure enzyme from 100 mL of culture. Biochemical characterization revealed that PmAcy possesses beneficial traits for industrial application like high temperature and pH-stability. A heat activation of PmAcy was observed upon incubation at temperatures up to 80 °C. Hydrolytic activity of PmAcy was detected with several N-acyl-amino acids as substrates and exhibited the highest conversion rate of 773 U/mg with N-lauroyl-L-alanine at 75 °C. The enzyme preferred long-chain acyl-amino-acids and displayed hardly any activity with acetyl-amino acids. PmAcy was also capable of N-acyl-amino acid synthesis with good conversion rates. The best synthesis results were obtained with the cationic L-amino acids L-arginine and L-lysine as well as with L-leucine and L-phenylalanine. Exemplarily, L-phenylalanine was acylated with fatty acids of chain lengths from C8 to C18 with conversion rates of up to 75\%. N-lauroyl-L-phenylalanine was purified by precipitation, and the structure of the reaction product was verified by LC-MS and NMR.}, language = {en} } @article{HeuermannErkens2006, author = {Heuermann, Holger and Erkens, H.}, title = {Novel RF switch concepts for differential wireless communications frontends. Erkens, H.; Heuermann, H.}, series = {IEEE Transactions on Microwave Theory and Techniques. 54 (2006), H. 6, Part 1}, journal = {IEEE Transactions on Microwave Theory and Techniques. 54 (2006), H. 6, Part 1}, isbn = {0018-9480}, pages = {2376 -- 2382}, year = {2006}, language = {en} } @article{HeuermannIbrahim2008, author = {Heuermann, Holger and Ibrahim, Irfan}, title = {Novel theory and architecture of a vector signal generator implemented with two PLLs / Ibrahim, Irfan ; Heuermann, Holger}, series = {European Conference on Wireless Technology, 2008. EuWiT 2008.}, journal = {European Conference on Wireless Technology, 2008. EuWiT 2008.}, isbn = {978-2-87487-008-8}, pages = {85 -- 88}, year = {2008}, language = {en} } @article{IkenKirsanovLeginetal.2012, author = {Iken, Heiko and Kirsanov, D. and Legin, A. and Sch{\"o}ning, Michael Josef}, title = {Novel Thin-Film Polymeric Materials for the Detection of Heavy Metals}, series = {Procedia Engineering}, journal = {Procedia Engineering}, number = {47}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2012.09.148}, pages = {322 -- 325}, year = {2012}, abstract = {A variety of transition metals, e.g., copper, zinc, cadmium, lead, etc. are widely used in industry as components for wires, coatings, alloys, batteries, paints and so on. The inevitable presence of transition metals in industrial processes implies the ambition of developing a proper analytical technique for their adequate monitoring. Most of these elements, especially lead and cadmium, are acutely toxic for biological organisms. Quantitative determination of these metals at low activity levels in different environmental and industrial samples is therefore a vital task. A promising approach to achieve an at-side or on-line monitoring on a miniaturized and cost efficient way is the combination of a common potentiometric sensor array with heavy metal-sensitive thin-film materials, like chalcogenide glasses and polymeric materials, respectively.}, language = {en} } @article{HeuermannThalayasingam2009, author = {Heuermann, Holger and Thalayasingam, K.}, title = {Novel vector non-linear measurement system for intermodulation measurements / Thalayasingam, K.; Heuermann, H.}, series = {European Microwave Conference, 2009 : EuMC 2009 ; Sept. 29, 2009 - Oct. 1, 2009, Rome, Italy ; part of European Microwave Week (EuMW) / sponsored by EuMA, European Microwave Association ... Endorsed by IEEE}, journal = {European Microwave Conference, 2009 : EuMC 2009 ; Sept. 29, 2009 - Oct. 1, 2009, Rome, Italy ; part of European Microwave Week (EuMW) / sponsored by EuMA, European Microwave Association ... Endorsed by IEEE}, publisher = {IEEE}, address = {Piscataway, NJ}, isbn = {978-1-4244-4748-0}, pages = {926 -- 929}, year = {2009}, language = {en} } @article{MonakhovaDiehl2022, author = {Monakhova, Yulia and Diehl, Bernd W.K.}, title = {Nuclear magnetic resonance spectroscopy as an elegant tool for a complete quality control of crude heparin material}, series = {Journal of Pharmaceutical and Biomedical Analysis}, volume = {219}, journal = {Journal of Pharmaceutical and Biomedical Analysis}, number = {Article number: 114915}, publisher = {Elsevier}, address = {New York, NY}, issn = {0731-7085}, doi = {10.1016/j.jpba.2022.114915}, year = {2022}, abstract = {Nuclear magnetic resonance (NMR) spectrometric methods for the quantitative analysis of pure heparin in crude heparin is proposed. For quantification, a two-step routine was developed using a USP heparin reference sample for calibration and benzoic acid as an internal standard. The method was successfully validated for its accuracy, reproducibility, and precision. The methodology was used to analyze 20 authentic porcine heparinoid samples having heparin content between 4.25 w/w \% and 64.4 w/w \%. The characterization of crude heparin products was further extended to a simultaneous analysis of these common ions: sodium, calcium, acetate and chloride. A significant, linear dependence was found between anticoagulant activity and assayed heparin content for thirteen heparinoids samples, for which reference data were available. A Diffused-ordered NMR experiment (DOSY) can be used for qualitative analysis of specific glycosaminoglycans (GAGs) in heparinoid matrices and, potentially, for quantitative prediction of molecular weight of GAGs. NMR spectrometry therefore represents a unique analytical method suitable for the simultaneous quantitative control of organic and inorganic composition of crude heparin samples (especially heparin content) as well as an estimation of other physical and quality parameters (molecular weight, animal origin and activity).}, language = {en} } @article{StanleyHorsburghRossetal.2006, author = {Stanley, Lesley A. and Horsburgh, Brian C. and Ross, Jillian and Scheer, Nico and Wolf, C. Roland}, title = {Nuclear Receptors which play a pivotal role in drug disposition and chemical toxicity}, series = {Drug Metabolism Reviews}, volume = {38}, journal = {Drug Metabolism Reviews}, number = {3}, issn = {1097-9883}, doi = {10.1080/03602530600786232}, pages = {515 -- 597}, year = {2006}, language = {en} }