@article{Kaemper1996, author = {K{\"a}mper, Klaus-Peter}, title = {Development of low-cost injection moulded micropumps. Entwicklung von kosteng{\"u}nstigen, mittels Spritzguß hergestellten Mikropumpen / D{\"o}pper, J. (u.a.)}, series = {Actuator 96 : Conference Proceedings ; 5th International Conference on New Actuators ; 26- 28 June, Bremen, Germany / Ed.: Hubert Borgmann. Publ. by: AXON Technology Consult GmbH}, journal = {Actuator 96 : Conference Proceedings ; 5th International Conference on New Actuators ; 26- 28 June, Bremen, Germany / Ed.: Hubert Borgmann. Publ. by: AXON Technology Consult GmbH}, address = {Bremen}, pages = {37 -- 40}, year = {1996}, language = {en} } @article{KaemperLehrEhrfeldetal.1997, author = {K{\"a}mper, Klaus-Peter and Lehr, H. and Ehrfeld, W. and Hagemann, B.}, title = {Development of micro and millimotors. Lehr, H.; Ehrfeld, W.; Hagemann, B.; K{\"a}mper, K.-P.; Michel, F.; Schulz, C.; Th{\"u}rigen C.}, series = {Minimally Invasive Therapy and Allied Technologies. 6 (1997)}, journal = {Minimally Invasive Therapy and Allied Technologies. 6 (1997)}, isbn = {1364-5706}, year = {1997}, language = {en} } @article{MourzinaSchubertZanderetal.2001, author = {Mourzina, Yu. G. and Schubert, J and Zander, W. and Legin, A. and Vlasov, Y. G. and L{\"u}th, H. and Sch{\"o}ning, Michael Josef}, title = {Development of multisensor systems based on chalcogenide thin film chemical sensors for the simultaneous multicomponent analysis of metal ions in complex solutions}, series = {Scaling down in electrochemistry : electrochemical micro- and nanosystem technology ; proceedings of the 3rd International Symposium on Electrochemical Microsystem Technologies, Garmisch-Patenkirchen, Germany, 11 - 15 September 2000 / ed. by J. W. Schultz}, journal = {Scaling down in electrochemistry : electrochemical micro- and nanosystem technology ; proceedings of the 3rd International Symposium on Electrochemical Microsystem Technologies, Garmisch-Patenkirchen, Germany, 11 - 15 September 2000 / ed. by J. W. Schultz}, publisher = {Elsevier [u.a.]}, address = {Amsterdam [u.a.]}, isbn = {0-08-044014-2}, pages = {251 -- 263}, year = {2001}, language = {en} } @article{IkenAhlbornGerlachetal.2013, author = {Iken, Heiko and Ahlborn, K. and Gerlach, F. and Vonau, W. and Zander, W. and Schubert, J. and Sch{\"o}ning, Michael Josef}, title = {Development of redox glasses and subsequent processing by means of pulsed laser deposition for realizing silicon-based thin-film sensors}, series = {Electrochimica acta}, journal = {Electrochimica acta}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-3859 (E-Journal); 0013-4686 (Print)}, pages = {Available online 30.8.2013}, year = {2013}, language = {en} } @article{ValeroBung2016, author = {Valero, Daniel and Bung, Daniel B.}, title = {Development of the interfacial air layer in the non-aerated region of high-velocity spillway flows: Instabilities growth, entrapped air and influence on the self-aeration onset}, series = {International Journal of Multiphase Flow}, volume = {84}, journal = {International Journal of Multiphase Flow}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0301-9322}, doi = {10.1016/j.ijmultiphaseflow.2016.04.012}, pages = {66 -- 74}, year = {2016}, abstract = {Self-aeration is traditionally explained by the water turbulent boundary layer outer edge intersection with the free surface. This paper presents a discussion on the commonly accepted hypothesis behind the computation of the critical point of self-aeration in spillway flows and a new formulation is proposed based on the existence of a developing air flow over the free surface. Upstream of the inception point of self-aeration, some surface roughening has been often reported in previous studies which consequently implies some entrapped air transport and air-water flows coupling. Such air flow is proven in this study by presenting measured air velocities and computing the air boundary layer thickness for a 1V:2H smooth chute flow. Additionally, the growth rate of free surface waves has been analysed by means of Ultrasonic Sensors measurements, obtaining also the entrapped air concentration. High-speed camera imaging has been used for qualitative study of the flow perturbations.}, language = {en} } @article{GuoMiyamotoWagneretal.2014, author = {Guo, Yuanyuan and Miyamoto, Ko-ichiro and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo}, title = {Device simulation of the light-addressable potentiometric sensor for the investigation of the spatial resolution}, series = {Sensors and actuators B: Chemical}, volume = {204}, journal = {Sensors and actuators B: Chemical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-3077 (E-Journal); 0925-4005 (Print)}, doi = {10.1016/j.snb.2014.08.016}, pages = {659 -- 665}, year = {2014}, abstract = {As a semiconductor-based electrochemical sensor, the light-addressable potentiometric sensor (LAPS) can realize two dimensional visualization of (bio-)chemical reactions at the sensor surface addressed by localized illumination. Thanks to this imaging capability, various applications in biochemical and biomedical fields are expected, for which the spatial resolution is critically significant. In this study, therefore, the spatial resolution of the LAPS was investigated in detail based on the device simulation. By calculating the spatiotemporal change of the distributions of electrons and holes inside the semiconductor layer in response to a modulated illumination, the photocurrent response as well as the spatial resolution was obtained as a function of various parameters such as the thickness of the Si substrate, the doping concentration, the wavelength and the intensity of illumination. The simulation results verified that both thinning the semiconductor substrate and increasing the doping concentration could improve the spatial resolution, which were in good agreement with known experimental results and theoretical analysis. More importantly, new findings of interests were also obtained. As for the dependence on the wavelength of illumination, it was found that the known dependence was not always the case. When the Si substrate was thick, a longer wavelength resulted in a higher spatial resolution which was known by experiments. When the Si substrate was thin, however, a longer wavelength of light resulted in a lower spatial resolution. This finding was explained as an effect of raised concentration of carriers, which reduced the thickness of the space charge region. The device simulation was found to be helpful to understand the relationship between the spatial resolution and device parameters, to understand the physics behind it, and to optimize the device structure and measurement conditions for realizing higher performance of chemical imaging systems.}, language = {en} } @article{GuoSekiMiyamotoetal.2014, author = {Guo, Yuanyuan and Seki, Kosuke and Miyamoto, Ko-ichiro and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo}, title = {Device simulation of the light-addressable potentiometric sensor with a novel photoexcitation method for a higher spatial resolution}, series = {Procedia Engineering}, volume = {87}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2014.11.369}, pages = {456 -- 459}, year = {2014}, abstract = {A novel photoexcitation method for the light-addressable potentiometric sensor (LAPS) realized a higher spatial resolution of chemical imaging. In this method, a modulated light probe, which generates the alternating photocurrent signal, is surrounded by a ring of constant light, which suppresses the lateral diffusion of photocarriers by enhancing recombination. A device simulation verified that a higher spatial resolution could be obtained by adjusting the gap between the modulated and constant light. It was also found that a higher intensity and a longer wavelength of constant light was more effective. However, there exists a tradeoff between the spatial resolution and the amplitude of the photocurrent, and thus, the signal-to-noise ratio. A tilted incidence of constant light was applied, which could achieve even higher resolution with a smaller loss of photocurrent.}, language = {en} } @article{HagemannBachmannLadeetal.1994, author = {Hagemann, Hans-J{\"u}rgen and Bachmann, P.K. and Lade, H. and Leers, D.}, title = {Diamond chemical vapor deposition: gas compositions and film properties / Bachmann, P.K.; Hagemann, H.-J.; Lade, H; Leers, D.; Picht, F.; Wiechert, D.U.; Wilson, H.}, series = {Diamond, SiC and nitride wide bandgap semiconductors : symposium held April 4 - 8, 1994, San Francisco, California, U.S.A. / ed.: Calvin H. Carter, Jr. ...}, journal = {Diamond, SiC and nitride wide bandgap semiconductors : symposium held April 4 - 8, 1994, San Francisco, California, U.S.A. / ed.: Calvin H. Carter, Jr. ...}, address = {Pittsburgh, Penn.}, isbn = {1-55899-239-1}, pages = {267 -- 277}, year = {1994}, language = {en} } @article{HagemannCassidy1994, author = {Hagemann, Hans-J{\"u}rgen and Cassidy, Wiliam D.}, title = {Diamond growth rates and quality: dependence on gas phase cpmposition / William D. Cassidy [...], Hans-Jurgen Hagemann}, series = {Diamond, SiC and nitride wide bandgap semiconductors : symposium held April 4 - 8, 1994, San Francisco, California, U.S.A. / ed.: Calvin H. Carter, Jr. ....}, journal = {Diamond, SiC and nitride wide bandgap semiconductors : symposium held April 4 - 8, 1994, San Francisco, California, U.S.A. / ed.: Calvin H. Carter, Jr. ....}, address = {Pittsburgh, Penn. ,}, isbn = {1-55899-239-1}, pages = {285 -- 291}, year = {1994}, language = {en} } @article{Mischke1995, author = {Mischke, Winfried}, title = {Die Garantie im Kaufrecht}, series = {Betriebs-Berater. 50 (1995), H. 22}, journal = {Betriebs-Berater. 50 (1995), H. 22}, isbn = {0340-7918}, pages = {1093 -- 1096}, year = {1995}, language = {en} } @article{KrauseMoellerMeurer1989, author = {Krause, Gregor and M{\"o}ller, K. and Meurer, D.}, title = {Dielectric phenomena in semicrystalline polymers}, series = {IEEE Transaction on Electrical Insulation. Vol. 24 (1989), H. No. 2}, journal = {IEEE Transaction on Electrical Insulation. Vol. 24 (1989), H. No. 2}, pages = {215 -- 222}, year = {1989}, language = {en} } @article{ChenJostVolkeretal.2017, author = {Chen, Chao and Jost, Peter and Volker, Hanno and Kaminski, Marvin and Wirtssohn, Matti R. and Engelmann, Ulrich M. and Kr{\"u}ger, K. and Schlich, Franziska F. and Schlockermann, Carl and Lobo, Ricardo P.S.M. and Wuttig, Matthias}, title = {Dielectric properties of amorphous phase-change materials}, series = {Physical Review B}, volume = {95}, journal = {Physical Review B}, number = {9}, issn = {2469-9950}, doi = {10.1103/PhysRevB.95.094111}, pages = {Article number 094111}, year = {2017}, language = {en} } @article{KrauseFruth1988, author = {Krause, Gregor and Fruth, B.}, title = {Dielectric Properties of Polyolefins Stressed by High Electrical Fields / Fruth, B. ; Krause, G.}, series = {Plenary lectures and contributions presented at the International Symposium on Polymer Materials : held in San Sebastian (Donostia), Spain, 31 August - 4 September, 1987 / symposium ed. G. M. Guzm{\´a}n ; A. Santamaria}, journal = {Plenary lectures and contributions presented at the International Symposium on Polymer Materials : held in San Sebastian (Donostia), Spain, 31 August - 4 September, 1987 / symposium ed. G. M. Guzm{\´a}n ; A. Santamaria}, publisher = {Huethig \& Wepf}, address = {Basel}, isbn = {3-85739-220-7}, pages = {XIV, 629 S.}, year = {1988}, language = {en} } @article{KrauseFruth1987, author = {Krause, Gregor and Fruth, Bernhard}, title = {Dielectric Properties of Polyolefins Stressed by High Electrical Fields. Fruth, B. ; Krause, G.}, year = {1987}, language = {en} } @article{BiselliNoll1998, author = {Biselli, Manfred and Noll, T.}, title = {Dielectric spectroscopy in the cultivation of suspended and immobilized hybridoma cells / Noll, T.; Biselli, M.}, series = {Journal of Biotechnology. 63 (1998), H. 3}, journal = {Journal of Biotechnology. 63 (1998), H. 3}, isbn = {0168-1656}, pages = {187 -- 198}, year = {1998}, language = {en} } @article{OezsoyluKizildagSchoeningetal.2020, author = {{\"O}zsoylu, Dua and Kizildag, Sefa and Sch{\"o}ning, Michael Josef and Wagner, Torsten}, title = {Differential chemical imaging of extracellular acidification within microfluidic channels using a plasma-functionalized light-addressable potentiometric sensor (LAPS)}, series = {Physics in Medicine}, volume = {10}, journal = {Physics in Medicine}, number = {100030}, publisher = {Elsevier}, address = {Amsterdam}, issn = {2352-4510}, doi = {10.1016/j.phmed.2020.100030}, pages = {8}, year = {2020}, abstract = {Extracellular acidification is a basic indicator for alterations in two vital metabolic pathways: glycolysis and cellular respiration. Measuring these alterations by monitoring extracellular acidification using cell-based biosensors such as LAPS plays an important role in studying these pathways whose disorders are associated with numerous diseases including cancer. However, the surface of the biosensors must be specially tailored to ensure high cell compatibility so that cells can represent more in vivo-like behavior, which is critical to gain more realistic in vitro results from the analyses, e.g., drug discovery experiments. In this work, O2 plasma patterning on the LAPS surface is studied to enhance surface features of the sensor chip, e.g., wettability and biofunctionality. The surface treated with O2 plasma for 30 s exhibits enhanced cytocompatibility for adherent CHO-K1 cells, which promotes cell spreading and proliferation. The plasma-modified LAPS chip is then integrated into a microfluidic system, which provides two identical channels to facilitate differential measurements of the extracellular acidification of CHO-K1 cells. To the best of our knowledge, it is the first time that extracellular acidification within microfluidic channels is quantitatively visualized as differential (bio-)chemical images.}, language = {en} } @article{DantismTakenagaWagneretal.2017, author = {Dantism, Shahriar and Takenaga, Shoko and Wagner, Torsten and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Differential imaging of the metabolism of bacteria and eukaryotic cells based on light-addressable potentiometric sensors}, series = {Electrochimica Acta}, volume = {246}, journal = {Electrochimica Acta}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0013-4686}, doi = {10.1016/j.electacta.2017.05.196}, pages = {234 -- 241}, year = {2017}, abstract = {A light-addressable potentiometric sensor (LAPS) is a field-effect-based potentiometric sensor with an electrolyte/insulator/semiconductor (EIS) structure, which is able to monitor analyte concentrations of (bio-)chemical species in aqueous solutions in a spatially resolved way. Therefore, it is also an appropriate tool to record 2D-chemical images of concentration variations on the sensor surface. In the present work, two differential, LAPS-based measurement principles are introduced to determine the metabolic activity of Escherichia coli (E. coli) K12 and Chinese hamster ovary (CHO) cells as test microorganisms. Hereby, we focus on i) the determination of the extracellular acidification rate (ΔpH/min) after adding glucose solutions to the cell suspensions; and ii) recording the amplitude increase of the photocurrent (Iph) related to the produced acids from E. coli K12 bacteria and CHO cells on the sensor surface by 2D-chemical imaging. For this purpose, 3D-printed multi-chamber structures were developed and mounted on the planar sensor-chip surface to define four independent compartments, enabling differential measurements with varying cell concentrations. The differential concept allows eliminating unwanted drift effects and, with the four-chamber structures, measurements on the different cell concentrations were performed simultaneously, thus reducing also the overall measuring time.}, language = {en} } @article{HeinzelSchaeferMuelleretal.2010, author = {Heinzel, Alexander and Sch{\"a}fer, Ralf and M{\"u}ller, Hans-Wilhelm and Schieffer, Andre and Ingenhag, Ariane and Northoff, Georg and Franz, Matthias and Hautzel, Hubertus}, title = {Differential modulation of valence and arousal in high-alexithymic and low-alexithymic individuals}, series = {Neuroreport}, volume = {21}, journal = {Neuroreport}, number = {15}, publisher = {Lippincott Williams \& Wilkins}, address = {London}, issn = {1473-558X}, doi = {10.1097/WNR.0b013e32833f38e0}, pages = {998 -- 1002}, year = {2010}, abstract = {High-alexithymic individuals are characterized by an impaired ability to identify and communicate emotions whereas low-alexithymic individuals have a wide-ranging ability to deal with emotions. This study examined the hypothesis that valence and arousal modifications of emotional stimuli differentially modulate cortical regions in high-alexithymic and low-alexithymic individuals. To this end, 28 high-alexithymic and 25 low-alexithymic individuals were investigated with event-related fMRI using visual emotional stimuli. We found differential neural activations in the dorsal anterior cingulate, the insula and the amygdala. We suggest that these differences may account for the impaired ability of high-alexithymic individuals to appropriately handle emotional stimuli.}, language = {en} } @article{CapitainRossJonesMoehringetal.2020, author = {Capitain, Charlotte and Ross-Jones, Jesse and M{\"o}hring, Sophie and Tippk{\"o}tter, Nils}, title = {Differential scanning calorimetry for quantification of polymer biodegradability in compost}, series = {International Biodeterioration \& Biodegradation}, volume = {149}, journal = {International Biodeterioration \& Biodegradation}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0964-8305}, doi = {10.1016/j.ibiod.2020.104914}, pages = {In Press, Article number 104914}, year = {2020}, abstract = {The objective of this study is the establishment of a differential scanning calorimetry (DSC) based method for online analysis of the biodegradation of polymers in complex environments. Structural changes during biodegradation, such as an increase in brittleness or crystallinity, can be detected by carefully observing characteristic changes in DSC profiles. Until now, DSC profiles have not been used to draw quantitative conclusions about biodegradation. A new method is presented for quantifying the biodegradation using DSC data, whereby the results were validated using two reference methods. The proposed method is applied to evaluate the biodegradation of three polymeric biomaterials: polyhydroxybutyrate (PHB), cellulose acetate (CA) and Organosolv lignin. The method is suitable for the precise quantification of the biodegradability of PHB. For CA and lignin, conclusions regarding their biodegradation can be drawn with lower resolutions. The proposed method is also able to quantify the biodegradation of blends or composite materials, which differentiates it from commonly used degradation detection methods.}, language = {en} } @article{MiyamotoYoshidaSakaietal.2011, author = {Miyamoto, Ko-ichiro and Yoshida, Midori and Sakai, Taito and Matsuzaka, Atsushi and Wagner, Torsten and Kanoh, Sanoh and Yoshinobu, Tatsuo and Sch{\"o}ning, Michael Josef}, title = {Differential setup of light-addressable potentiometric sensor with an enzyme reactor in a flow channel}, series = {Japanese Journal of Applied Physics. 50 (2011)}, journal = {Japanese Journal of Applied Physics. 50 (2011)}, publisher = {Japan Society of Applied Physics}, address = {Bristol}, isbn = {0021-4922}, pages = {04DL08-1 -- 04DL08-5}, year = {2011}, language = {en} }