@article{HillgaertnerPeier2006,
  author    = {Hillg{\"a}rtner, Michael and Peier, Dirk},
  title     = {Design of a Measurement Setup for the Impedance of Low-Resistance Plate-Conductors in the RF-Range},
  series = {Proceedings of the 10th International Conference on Optimization of Electrical and Electronic Equipment, OPTIM '06, Bra\&\#351;ov, May 18 - 20, 2006 / ed. by The Transilvania University of Bra\&\#351;ov, Faculty of Electrical Engineering and Computer Science. [Ed. Mihai Cernat .\&\#804;] . - Vol. 1: Keynote addresses, electrotechnics},
  journal   = {Proceedings of the 10th International Conference on Optimization of Electrical and Electronic Equipment, OPTIM '06, Bra\&\#351;ov, May 18 - 20, 2006 / ed. by The Transilvania University of Bra\&\#351;ov, Faculty of Electrical Engineering and Computer Science. [Ed. Mihai Cernat .\&\#804;] . - Vol. 1: Keynote addresses, electrotechnics},
  address   = {Bra\&\#351;ov},
  isbn      = {978-973-635703-9},
  pages     = {59 -- 64},
  year      = {2006},
  language  = {en}
}
@article{FrankoDuKallweitetal.2020,
  author    = {Franko, Josef and Du, Shengzhi and Kallweit, Stephan and Duelberg, Enno Sebastian and Engemann, Heiko},
  title     = {Design of a Multi-Robot System for Wind Turbine Maintenance},
  series = {Energies},
  volume    = {13},
  journal   = {Energies},
  number    = {10},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1996-1073},
  doi       = {10.3390/en13102552},
  pages     = {Article 2552},
  year      = {2020},
  abstract  = {The maintenance of wind turbines is of growing importance considering the transition to renewable energy. This paper presents a multi-robot-approach for automated wind turbine maintenance including a novel climbing robot. Currently, wind turbine maintenance remains a manual task, which is monotonous, dangerous, and also physically demanding due to the large scale of wind turbines. Technical climbers are required to work at significant heights, even in bad weather conditions. Furthermore, a skilled labor force with sufficient knowledge in repairing fiber composite material is rare. Autonomous mobile systems enable the digitization of the maintenance process. They can be designed for weather-independent operations. This work contributes to the development and experimental validation of a maintenance system consisting of multiple robotic platforms for a variety of tasks, such as wind turbine tower and rotor blade service. In this work, multicopters with vision and LiDAR sensors for global inspection are used to guide slower climbing robots. Light-weight magnetic climbers with surface contact were used to analyze structure parts with non-destructive inspection methods and to locally repair smaller defects. Localization was enabled by adapting odometry for conical-shaped surfaces considering additional navigation sensors. Magnets were suitable for steel towers to clamp onto the surface. A friction-based climbing ring robot (SMART— Scanning, Monitoring, Analyzing, Repair and Transportation) completed the set-up for higher payload. The maintenance period could be extended by using weather-proofed maintenance robots. The multi-robot-system was running the Robot Operating System (ROS). Additionally, first steps towards machine learning would enable maintenance staff to use pattern classification for fault diagnosis in order to operate safely from the ground in the future.},
  language  = {en}
}
@article{KalbeHoeckerBerndt1989,
  author    = {Kalbe, Jochen and H{\"o}cker, Hartwig and Berndt, Heinz},
  title     = {Design of enzyme reactors as chromatographic columns for racemic resolution of amino acid esters},
  series = {Chromatographia},
  volume    = {28},
  journal   = {Chromatographia},
  number    = {3-4},
  isbn      = {0009-5893},
  doi       = {10.1007/BF02319646},
  pages     = {193 -- 196},
  year      = {1989},
  language  = {en}
}
@article{HillgaertnerStoniesPeieretal.2005,
  author    = {Hillg{\"a}rtner, Michael and Stonies, R. and Peier, D. and Voges, E.},
  title     = {Design of Low Cost Antennas for Reverberation Chambers},
  series = {Proceedings of the 16th International Zurich Symposium on Electromagnetic Compatibility : [EMC Week 2005, Zurich, Switzerland, February 13 - 18 ; technical exhibition on EMC and RF/microwave Measurements and Instrumentation (February 15 - 17)] / [Laboratory for Electromagnetic Fields and Microwave Electronics, Swiss Federal Institute of Technology Zurich]},
  journal   = {Proceedings of the 16th International Zurich Symposium on Electromagnetic Compatibility : [EMC Week 2005, Zurich, Switzerland, February 13 - 18 ; technical exhibition on EMC and RF/microwave Measurements and Instrumentation (February 15 - 17)] / [Laboratory for Electromagnetic Fields and Microwave Electronics, Swiss Federal Institute of Technology Zurich]},
  publisher = {ETH-Zentrum-IFH},
  address   = {Z{\"u}rich},
  isbn      = {3-9521199-9-7},
  pages     = {1 CD-ROM. ; 12 cm},
  year      = {2005},
  language  = {en}
}
@article{KuertenMottaghyZiegler2015,
  author    = {K{\"u}rten, Sylvia and Mottaghy, Darius and Ziegler, Martin},
  title     = {Design of plane energy geostructures based on laboratory tests and numerical modelling},
  series = {Energy and Buildings},
  volume    = {107},
  journal   = {Energy and Buildings},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0378-7788},
  doi       = {10.1016/j.enbuild.2015.08.039},
  pages     = {434 -- 444},
  year      = {2015},
  language  = {en}
}
@article{HeinrichsPietrzykZiemons2003,
  author    = {Heinrichs, U. and Pietrzyk, U. and Ziemons, Karl},
  title     = {Design optimization of the PMT-ClearPET prototypes based on simulation studies with GEANT3},
  series = {2002 IEEE Nuclear Science Symposium Conference Record, Vol. 3},
  journal   = {2002 IEEE Nuclear Science Symposium Conference Record, Vol. 3},
  issn      = {1082-3654},
  pages     = {682 -- 686},
  year      = {2003},
  abstract  = {Within the Crystal Clear Collaboration four centres are developing 2nd generation high performance small animal PET scanners for different kinds of animals and medical applications. The first prototypes are PMT-based systems including depth of interaction (DOI) detection by using a phoswich layer of LSO and LuYAP. The aim of these simulation studies is to optimize sensitivity and spatial resolution of given designs, which vary in FOVs caused by different detector configurations (ring/octagon) and sizes. For this purpose the simulation tool GEANT3 (CERN) was used. The simulations have shown that all PMT designs with one-to-one coupling of crystals have a very nonlinear axial sensitivity profile. By shifting every other PMT 1/4 of a PMT length in axial direction the sampling of the FOVs became more homogeneous. At an energy threshold of 350keV the regression coefficient increases from 0.818 for the non-shifted to 0.993 for the shifted design. Simulations of a point source centred in the FOV (threshold: 350keV) resulted in sensitivities of 4.2\% for a 4×20PMT (LSO/LuYAP a 10mm) and 3.8\% for a 4×16PMT (LSO/LuYAP a 8mm) ring design. The 3D-MLEM reconstruction of a point source shows the enormous improvement of resolution using a crystal double layer with DOI (3.1mm at 40mm from CFOV) instead of a 20mm single layer (11.9mm).},
  language  = {en}
}
@article{HeinrichsPietrzykZiemons2003,
  author    = {Heinrichs, U. and Pietrzyk, U. and Ziemons, Karl},
  title     = {Design optimization of the PMT-ClearPET prototypes based on simulation studies with GEANT3},
  series = {IEEE Transactions on Nuclear Science},
  volume    = {50},
  journal   = {IEEE Transactions on Nuclear Science},
  number    = {5},
  isbn      = {0018-9499},
  pages     = {1428 -- 1432},
  year      = {2003},
  abstract  = {Within the Crystal Clear Collaboration (CCC), four centers are developing second generation high performance small animal positron emission tomography (PET) scanners for different kinds of animals and medical applications. The first prototypes are photomultiplier tube (PMT)-based systems including depth of interaction (DOI) detection by using a phoswich layer of lutetium oxyorthosilicate (LSO) and lutetium yttrium aluminum perovskite (LuYAP). The aim of these simulation studies is to optimize sensitivity and spatial resolution of given designs, which vary in fields of view (FOVs) caused by different detector configurations (ring/octagon) and sizes. For this purpose the simulation tool GEANT3 (CERN, Geneva, Switzerland) was used.},
  language  = {en}
}
@article{NiemuellerFerreinBecketal.2010,
  author    = {Niem{\"u}ller, Tim and Ferrein, Alexander and Beck, Daniel and Lakemeyer, Gerhard},
  title     = {Design Principles of the Component-Based Robot Software Framework Fawkes},
  series = {Simulation, Modeling, and Programming for Autonomous Robots},
  journal   = {Simulation, Modeling, and Programming for Autonomous Robots},
  pages     = {300 -- 311},
  year      = {2010},
  language  = {en}
}
@inproceedings{HardtAbdelGawadMartinetal.1975,
  author    = {Hardt, Arno and Abdel-Gawad, A and Martin, S. and Reich, J.},
  title     = {Design procedures for the Juelich QQDDQ high resolution spectrometer},
  series = {Proceedings, 5th International Conference on Magnet Technology (MT-5) : Rome, Italy, April 21-25, 1975},
  booktitle = {Proceedings, 5th International Conference on Magnet Technology (MT-5) : Rome, Italy, April 21-25, 1975},
  pages     = {45 -- 51},
  year      = {1975},
  language  = {en}
}
@inproceedings{StarkBartelDitscheetal.2023,
  author    = {Stark, Ralf and Bartel, Sebastian and Ditsche, Florian and Esch, Thomas},
  title     = {Design study of a 30kN LOX/LCH4 aerospike rocket engine for lunar lander application},
  series = {Aerospace Europe Conference 2023 - 10th EUCASS - 9th CEAS},
  booktitle = {Aerospace Europe Conference 2023 - 10th EUCASS - 9th CEAS},
  pages     = {9 Seiten},
  year      = {2023},
  abstract  = {Based on lunar lander concept EL3, various LOX/CH4 aerospike engines were studied. A distinction was made between single and cluster configurations as well as ideal and non-ideal contour concepts. It could be shown that non-ideal aerospike engines promise a significant payload gain.},
  language  = {en}
}
@misc{GraesslRenzHezeletal.2012,
  author    = {Gr{\"a}ßl, Andreas and Renz, Wolfgang and Hezel, Fabian and Frauenrath, Tobias and Pfeiffer, Harald and Hoffmann, Werner and Kellmann, Peter and Martin, Conrad and Niendorf, Thoralf},
  title     = {Design, evaluation and application of a modular 32 channel transmit/receive surface coil array for cardiac MRI at 7T},
  series = {2012 ISMRM Annual Meeting Proceedings},
  journal   = {2012 ISMRM Annual Meeting Proceedings},
  issn      = {1545-4428},
  year      = {2012},
  abstract  = {Cardiac MR (CMR) at ultrahigh (≥7.0 T) fields is regarded as one of the most challenging MRI applications. At 7.0 T image quality is not always exclusively defined by signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR). Detrimental effects bear the potential to spoil the signal-to-noise (SNR) and contrast-to-noise (CNR) benefits of cardiac MR (CMR) at 7.0 T. B₁⁺-inhomogeneities and signal voids represent the main challenges. Various pioneering coil concepts have been proposed to tackle these issues, enabling cardiac MRI at 7.0 T. This includes a trend towards an ever larger number of transmit and receive channels. This approach affords multi-dimensional B₁⁺ modulations to improve B₁⁺ shimming performance and to enhance RF efficiency. Also, parallel imaging benefits from a high number of receive channels enabling two-dimensional acceleration. Realizing the limitations of existing coil designs tailored for UHF CMR and recognizing the opportunities of a many element TX/RX channel architecture this work proposes a modular, two dimensional 32-channel transmit and receive array using loop elements and examines its efficacy for enhanced B¹+ homogeneity and improved parallel imaging performance.},
  language  = {en}
}
@article{ChoiFelderFelderetal.2020,
  author    = {Choi, Chang-Hoon and Felder, Tim and Felder, J{\"o}rg and Tellmann, Lutz and Hong, Suk-Min and Wegener, Hans-Peter and Shah, N Jon and Ziemons, Karl},
  title     = {Design, evaluation and comparison of endorectal coils for hybrid MR-PET imaging of the prostate},
  series = {Physics in Medicine \& Biology},
  volume    = {65},
  journal   = {Physics in Medicine \& Biology},
  number    = {11},
  publisher = {IOP},
  address   = {Bristol},
  issn      = {0031-9155},
  doi       = {10.1088/1361-6560/ab87f8},
  year      = {2020},
  abstract  = {Prostate cancer is one of the most common cancers among men and its early detection is critical for its successful treatment. The use of multimodal imaging, such as MR-PET, is most advantageous as it is able to provide detailed information about the prostate. However, as the human prostate is flexible and can move into different positions under external conditions, it is important to localise the focused region-of-interest using both MRI and PET under identical circumstances. In this work, we designed five commonly used linear and quadrature radiofrequency surface coils suitable for hybrid MR-PET use in endorectal applications. Due to the endorectal design and the shielded PET insert, the outer face of the coils investigated was curved and the region to be imaged was outside the volume of the coil. The tilting angles of the coils were varied with respect to the main magnetic field direction. This was done to approximate the various positions from which the prostate could be imaged. The transmit efficiencies and safety excitation efficiencies from simulations, together with the signal-to-noise ratios from the MR images were calculated and analysed. Overall, it was found that the overlapped loops driven in quadrature were superior to the other types of coils we tested. In order to determine the effect of the different coil designs on PET, transmission scans were carried out, and it was observed that the differences between attenuation maps with and without the coils were negligible. The findings of this work can provide useful guidance for the integration of such coil designs into MR-PET hybrid systems in the future.},
  language  = {en}
}
@inproceedings{OstkottePetersHueningetal.2022,
  author    = {Ostkotte, Sebastian and Peters, Constantin and H{\"u}ning, Felix and Bragard, Michael},
  title     = {Design, implementation and verification of an rotational incremental position encoder based on the magnetic Wiegand effect},
  series = {2022 ELEKTRO (ELEKTRO)},
  booktitle = {2022 ELEKTRO (ELEKTRO)},
  publisher = {IEEE},
  isbn      = {978-1-6654-6726-1},
  issn      = {2691-0616},
  doi       = {10.1109/ELEKTRO53996.2022.9803477},
  pages     = {6 Seiten},
  year      = {2022},
  abstract  = {This paper covers the use of the magnetic Wiegand effect to design an innovative incremental encoder. First, a theoretical design is given, followed by an estimation of the achievable accuracy and an optimization in open-loop operation. Finally, a successful experimental verification is presented. For this purpose, a permanent magnet synchronous machine is controlled in a field-oriented manner, using the angle information of the prototype.},
  language  = {en}
}
@article{LeursMezoOehlschlaegeretal.2012,
  author    = {Leurs, Ulrike and Mezo, Gabor and {\"O}hlschl{\"a}ger, Peter and Orban, Erika and Marquard, Andrea and Manea, Marilena},
  title     = {Design, synthesis, in vitro stability and cytostatic effect of multifunctional anticancer drug-bioconjugates containing GnRH-III as a targeting moiety},
  series = {Peptide Science},
  volume    = {98},
  journal   = {Peptide Science},
  number    = {1},
  publisher = {Wiley},
  address   = {New York, NY},
  issn      = {1097-0282},
  doi       = {10.1002/bip.21640},
  pages     = {1 -- 10},
  year      = {2012},
  abstract  = {Bioconjugates containing the GnRH-III hormone decapeptide as a targeting moiety are able to deliver chemotherapeutic agents specifically to cancer cells expressing GnRH receptors, thereby increasing their local efficacy while limiting the peripheral toxicity. However, the number of GnRH receptors on cancer cells is limited and they desensitize under continuous hormone treatment. A possible approach to increase the receptor mediated tumor targeting and consequently the cytostatic effect of the bioconjugates would be the attachment of more than one chemotherapeutic agent to one GnRH-III molecule. Here we report on the design, synthesis and biochemical characterization of multifunctional bioconjugates containing GnRH-III as a targeting moiety and daunorubicin as a chemotherapeutic agent. Two different drug design approaches were pursued. The first one was based on the bifunctional [4Lys]-GnRH-III (Glp-His-Trp-Lys-His-Asp-Trp-Lys-Pro-Gly-NH2) containing two lysine residues in positions 4 and 8, whose ϵ-amino groups were used for the coupling of daunorubicin. In the second drug design, the native GnRH-III (Glp-His-Trp-Ser-His-Asp-Trp-Lys-Pro-Gly-NH2) was used as a scaffold; an additional lysine residue was coupled to the ϵ-amino group of 8Lys in order to generate two free amino groups available for conjugation of daunorubicin. The in vitro stability/degradation of all synthesized compounds was investigated in human serum, as well as in the presence of rat liver lysosomal homogenate. Their cellular uptake was determined on human breast cancer cells and the cytostatic effect was evaluated on human breast, colon and prostate cancer cell lines. Compared with a monofunctional compound, both drug design approaches resulted in multifunctional bioconjugates with increased cytostatic effect.},
  language  = {en}
}
@incollection{AltherrEdererLorenzetal.2016,
  author    = {Altherr, Lena and Ederer, Thorsten and Lorenz, Ulf and Pelz, Peter F. and P{\"o}ttgen, Philipp},
  title     = {Designing a feedback control system via mixed-integer programming},
  series = {Operations Research Proceedings 2014: Selected Papers of the Annual International Conference of the German Operations Research},
  booktitle = {Operations Research Proceedings 2014: Selected Papers of the Annual International Conference of the German Operations Research},
  editor    = {L{\"u}bbecke, Marco E. and Koster, Arie and Letmathe, Peter and Madlener, Reihard and Preis, Britta and Walther, Grit},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-28695-2},
  doi       = {10.1007/978-3-319-28697-6_18},
  pages     = {121 -- 127},
  year      = {2016},
  abstract  = {Pure analytical or experimental methods can only find a control strategy for technical systems with a fixed setup. In former contributions we presented an approach that simultaneously finds the optimal topology and the optimal open-loop control of a system via Mixed Integer Linear Programming (MILP). In order to extend this approach by a closed-loop control we present a Mixed Integer Program for a time discretized tank level control. This model is the basis for an extension by combinatorial decisions and thus for the variation of the network topology. Furthermore, one is able to appraise feasible solutions using the global optimality gap.},
  language  = {en}
}
@article{BitzFelderWittig2013,
  author    = {Bitz, Andreas and Felder, Jorg and Wittig, Tilmann},
  title     = {Designing MRI Coils with Aid of Simulation},
  series = {Microwaves \& RF},
  volume    = {52},
  journal   = {Microwaves \& RF},
  number    = {7},
  publisher = {Penton},
  address   = {Cleveland, Ohio},
  issn      = {0745-2993},
  pages     = {56},
  year      = {2013},
  language  = {en}
}
@article{BindalSharmaJanseretal.2013,
  author    = {Bindal, Gaurav and Sharma, Sparsh and Janser, Frank and Neu, Eugen},
  title     = {Detailed analysis of variables affecting wing kinematics of bat flight},
  series = {SAE International Journal of Aerospace},
  volume    = {6},
  journal   = {SAE International Journal of Aerospace},
  number    = {2},
  issn      = {1946-3901},
  doi       = {10.4271/2013-01-9003},
  pages     = {811 -- 818},
  year      = {2013},
  language  = {en}
}
@inproceedings{RochefortVerverGrunendahletal.2005,
  author    = {Rochefort, E. de and Verver, M. and Grunendahl, A. and Mooi, H. and Butenweg, Christoph},
  title     = {Detailed modelling of the lumbar spine for investigation of low back pain},
  series = {Digital Human Modeling for Design and Engineering Symposium : Iowa City, Iowa June 14-16, 2005. (SAE technical papers series ; 2005-1-2716)},
  booktitle = {Digital Human Modeling for Design and Engineering Symposium : Iowa City, Iowa June 14-16, 2005. (SAE technical papers series ; 2005-1-2716)},
  publisher = {SAE International},
  address   = {Warrendale, Pa.},
  organization    = {Society of Automotive Engineers},
  issn      = {0096-736X},
  doi       = {10.4271/2005-01-2716},
  pages     = {1 -- 11},
  year      = {2005},
  language  = {en}
}
@article{RochefortVerverGrunendahletal.2005,
  author    = {Rochefort, E. de and Verver, M. and Grunendahl, A. and Mooi, H. and Butenweg, Christoph},
  title     = {Detailed modelling of the lumbar spine for investigations of low back pain},
  series = {SAE transactions : papers presented at Society and Section meetings / Society of Automotive Engineers},
  volume    = {Volume 114},
  journal   = {SAE transactions : papers presented at Society and Section meetings / Society of Automotive Engineers},
  number    = {Part 7},
  organization    = {Society of Automotive Engineers},
  issn      = {0096-736X},
  pages     = {788 -- 796},
  year      = {2005},
  language  = {en}
}
@article{FrauenrathFuchsDieringeretal.2012,
  author    = {Frauenrath, Tobias and Fuchs, Katharina and Dieringer, Matthias A. and {\"O}zerdem, Celal and Patel, Nishan and Renz, Wolfgang and Greiser, Andreas and Elgeti, Thomas and Niendorf, Thoralf},
  title     = {Detailing the use of magnetohydrodynamic effects for synchronization of MRI with the cardiac cycle: A feasibility study},
  series = {Journal of Magnetic Resonance Imaging},
  volume    = {36},
  journal   = {Journal of Magnetic Resonance Imaging},
  number    = {2},
  publisher = {Wiley-Liss},
  address   = {New York},
  issn      = {1522-2586},
  doi       = {10.1002/jmri.23634},
  pages     = {364 -- 372},
  year      = {2012},
  abstract  = {Purpose: To investigate the feasibility of using magnetohydrodynamic (MHD) effects for synchronization of magnetic resonance imaging (MRI) with the cardiac cycle. Materials and Methods: The MHD effect was scrutinized using a pulsatile flow phantom at B0 = 7.0 T. MHD effects were examined in vivo in healthy volunteers (n = 10) for B0 ranging from 0.05-7.0 T. Noncontrast-enhanced MR angiography (MRA) of the carotids was performed using a gated steady-state free-precession (SSFP) imaging technique in conjunction with electrocardiogram (ECG) and MHD synchronization. Results: The MHD potential correlates with flow velocities derived from phase contrast MRI. MHD voltages depend on the orientation between B0 and the flow of a conductive fluid. An increase in the interelectrode spacing along the flow increases the MHD potential. In vivo measurement of the MHD effect provides peak voltages of 1.5 mV for surface areas close to the common carotid artery at B0 = 7.0 T. Synchronization of MRI with the cardiac cycle using MHD triggering is feasible. MHD triggered MRA of the carotids at 3.0 T showed an overall image quality and richness of anatomic detail, which is comparable to ECG-triggered MRAs. Conclusion: This feasibility study demonstrates the use of MHD effects for synchronization of MR acquisitions with the cardiac cycle. J. Magn. Reson. Imaging 2012;36:364-372. © 2012 Wiley Periodicals, Inc.},
  language  = {en}
}