@inproceedings{PothMonzonTippkoetteretal.2010,
  author    = {Poth, Sebastian and Monzon, Magaly and Tippk{\"o}tter, Nils and Ulber, Roland},
  title     = {Lignocellulosic biorefinery : process integration of hydrolysis and fermentation},
  series = {Proceedings / 11th European Workshop on Lignocellulosics and Pulp : August 16 - 19, 2010, Hamburg, Germany},
  booktitle = {Proceedings / 11th European Workshop on Lignocellulosics and Pulp : August 16 - 19, 2010, Hamburg, Germany},
  publisher = {vTi},
  address   = {Hamburg},
  pages     = {65 -- 68},
  year      = {2010},
  language  = {en}
}
@inproceedings{StaatHeitzer1997,
  author    = {Staat, Manfred and Heitzer, Michael},
  title     = {Limit and shakedown analysis for plastic design},
  year      = {1997},
  abstract  = {Limit and shakedown theorems are exact theories of classical plasticity for the direct computation of safety factors or of the load carrying capacity under constant and varying loads. Simple versions of limit and shakedown analysis are the basis of all design codes for pressure vessels and pipings. Using Finite Element Methods more realistic modeling can be used for a more rational design. The methods can be extended to yield optimum plastic design. In this paper we present a first implementation in FE of limit and shakedown analyses for perfectly plastic material. Limit and shakedown analyses are done of a pipe-junction and a interaction diagram is calculated. The results are in good correspondence with the analytic solution we give in the appendix.},
  subject      = {Einspielen <Werkstoff>},
  language  = {en}
}
@inproceedings{TranTrinhDaoetal.2022,
  author    = {Tran, Ngoc Trinh and Trinh, Tu Luc and Dao, Ngoc Tien and Giap, Van Tan and Truong, Manh Khuyen and Dinh, Thuy Ha and Staat, Manfred},
  title     = {Limit and shakedown analysis of structures under random strength},
  series = {Proceedings of (NACOME2022) The 11th National Conference on Mechanics, Vol. 1. Solid Mechanics, Rock Mechanics, Artificial Intelligence, Teaching and Training, Hanoi, December 2-3, 2022},
  booktitle = {Proceedings of (NACOME2022) The 11th National Conference on Mechanics, Vol. 1. Solid Mechanics, Rock Mechanics, Artificial Intelligence, Teaching and Training, Hanoi, December 2-3, 2022},
  publisher = {Nha xuat ban Khoa hoc tu nhien va Cong nghe (Verlag Naturwissenschaft und Technik)},
  address   = {Hanoi},
  isbn      = {978-604-357-084-7},
  pages     = {510 -- 518},
  year      = {2022},
  abstract  = {Direct methods comprising limit and shakedown analysis is a branch of computational mechanics. It plays a significant role in mechanical and civil engineering design. The concept of direct method aims to determinate the ultimate load bearing capacity of structures beyond the elastic range. For practical problems, the direct methods lead to nonlinear convex optimization problems with a large number of variables and onstraints. If strength and loading are random quantities, the problem of shakedown analysis is considered as stochastic programming. This paper presents a method so called chance constrained programming, an effective method of stochastic programming, to solve shakedown analysis problem under random condition of strength. In this our investigation, the loading is deterministic, the strength is distributed as normal or lognormal variables.},
  language  = {en}
}
@inproceedings{Staat2012,
  author    = {Staat, Manfred},
  title     = {Limit and shakedown analysis under uncertainty},
  series = {Proceedings International Conference on Advances in Computational Mechanics (ACOME)},
  booktitle = {Proceedings International Conference on Advances in Computational Mechanics (ACOME)},
  pages     = {837 -- 861},
  year      = {2012},
  language  = {de}
}
@inproceedings{StaatTranPham2008,
  author    = {Staat, Manfred and Tran, Thanh Ngoc and Pham, Phu Tinh},
  title     = {Limit and shakedown reliability analysis by nonlinear programming},
  year      = {2008},
  abstract  = {7th International Conference on Reliability of Materials and Structures (RELMAS 2008). June 17 - 20, 2008 ; Saint Petersburg, Russia. pp 354-358. Reprint with corrections in red Introduction Analysis of advanced structures working under extreme heavy loading such as nuclear power plants and piping system should take into account the randomness of loading, geometrical and material parameters. The existing reliability are restricted mostly to the elastic working regime, e.g. allowable local stresses. Development of the limit and shakedown reliability-based analysis and design methods, exploiting potential of the shakedown working regime, is highly needed. In this paper the application of a new algorithm of probabilistic limit and shakedown analysis for shell structures is presented, in which the loading and strength of the material as well as the thickness of the shell are considered as random variables. The reliability analysis problems may be efficiently solved by using a system combining the available FE codes, a deterministic limit and shakedown analysis, and the First and Second Order Reliability Methods (FORM/SORM). Non-linear sensitivity analyses are obtained directly from the solution of the deterministic problem without extra computational costs.},
  subject      = {Finite-Elemente-Methode},
  language  = {en}
}
@inproceedings{StaatHeitzerHicken1999,
  author    = {Staat, Manfred and Heitzer, Michael and Hicken, E. F.},
  title     = {LISA - ein europ{\"a}isches Projekt zur FEM-basierten Traglast- und Einspielanalyse},
  year      = {1999},
  abstract  = {Traglast- und Einspielanalysen sind vereinfachte doch exakte Verfahren der Plastizit{\"a}t, die neben ausreichender Verformbarkeit keine einschr{\"a}nkenden Voraussetzungen beinhalten. Die Vereinfachungen betreffen die Beschaffung der Daten und Modelle f{\"u}r Details der Lastgeschichte und des Stoffverhaltens. Anders als die klassische Behandlung nichtlinearer Probleme der Strukturmechanik f{\"u}hrt die Methode auf Optimierungsprobleme. Diese sind bei realistischen FEM-Modellen sehr groß. Das hat die industrielle Anwendung der Traglast- und Einspielanalysen stark verz{\"o}gert. Diese Situation wird durch das Brite-EuRam Projekt LISA grundlegend ge{\"a}ndert. In LISA entsteht auf der Basis des industriellen FEM-Programms PERMAS ein Verfahren zur direkten Berechnung der Tragf{\"a}higkeit duktiler Strukturen. Damit kann der Betriebsbereich von Komponenten und Bauwerken auf den plastischen Bereich erweitert werden, ohne den Aufwand gegen{\"u}ber elastischen Analysen wesentlich zu erh{\"o}hen. Die beachtlichen Rechenzeitgewinne erlauben Parameterstudien und die Berechnung von Interaktionsdiagrammen, die einen schnellen {\"U}berblick {\"u}ber m{\"o}gliche Betriebsbereiche vermitteln. Es zeigt sich, daß abh{\"a}ngig von der Komponente und ihren Belastungen teilweise entscheidende Sicherheitsgewinne zur Erweiterung der Betriebsbereiche erzielt werden k{\"o}nnen. Das Vorgehen erfordert vom Anwender oft ein gewisses Umdenken. Es werden keine Spannungen berechnet, um damit Sicherheit und Lebensdauer zu interpretieren. Statt dessen berechnet man direkt die gesuchte Sicherheit. Der Post-Prozessor wird nur noch zur Modell- und Rechenkontrolle ben{\"o}tigt. Das Vorgehen ist {\"a}hnlich der Stabilit{\"a}tsanalyse (Knicken, Beulen). Durch namhafte industrielle Projektpartner werden Validierung und die Anwendbarkeit auf eine breite Palette technischer Probleme garantiert. Die ebenfalls in LISA entwickelten Zuverl{\"a}ssigkeitsanalysen sind nichlinear erst auf der Basis direkter Verfahren effektiv m{\"o}glich. Ohne Traglast- und Einspielanalyse ist plastische Strukturoptimierung auch heute kaum durchf{\"u}hrbar. Auf die vorgesehenen Erweiterungen der Werkstoffmodellierung f{\"u}r nichtlineare Verfestigung und f{\"u}r Sch{\"a}digung konnte hier nicht eingegangen werden. Es herrscht ein deutlicher Mangel an Experimenten zum Nachweis der Grenzen zwischen elastischem Einspielen und dem Versagen durch LCF oder durch Ratchetting.},
  subject      = {Einspielen <Werkstoff>},
  language  = {de}
}
@inproceedings{StaatHeitzerHicken1998,
  author    = {Staat, Manfred and Heitzer, M. and Hicken, E. F.},
  title     = {LISA, ein europ{\"a}isches Projekt zur direkten Berechnung der Tragf{\"a}higkeit duktiler Strukturen},
  year      = {1998},
  abstract  = {Traglast- und Einspielanalysen sind vereinfachte doch exakte Verfahren der Plastizit{\"a}t, die neben ausreichender Verformbarkeit keine einschr{\"a}nkenden Voraussetzungen beinhalten. Die Vereinfachungen betreffen die Beschaffung der Daten und Modelle f{\"u}r Details der Lastgeschichte und des Stoffverhaltens. Anders als die klassische Behandlung nichtlinearer Probleme der Strukturmechanik f{\"u}hrt die Methode auf Optimierungsprobleme. Diese sind bei realistischen FEM-Modellen sehr groß. Das hat die industrielle Anwendung der Traglast- und Einspielanalysen stark verz{\"o}gert. Diese Situation wird durch das Brite-EuRam Projekt LISA grundlegend ge{\"a}ndert. Die Autoren m{\"o}chten der Europ{\"a}ischen Kommission an dieser Stelle f{\"u}r die F{\"o}rderung ausdr{\"u}cklich danken. In LISA entsteht auf der Basis des industriellen FEM-Programms PERMAS ein Verfahren zur direkten Berechnung der Tragf{\"a}higkeit duktiler Strukturen. Damit kann der Betriebsbereich von Komponenten und Bauwerken auf den plastischen Bereich erweitert werden, ohne den Aufwand gegen{\"u}ber elastischen Analysen wesentlich zu erh{\"o}hen. Die beachtlichen Rechenzeitgewinne erlauben Parameterstudien und die Berechnung von Interaktionsdiagrammen, die einen schnellen {\"U}berblick {\"u}ber m{\"o}gliche Betriebsbereiche vermitteln. Es zeigt sich, daß abh{\"a}ngig von der Komponente und ihren Belastungen teilweise entscheidende Sicherheitsgewinne zur Erweiterung der Betriebsbereiche erzielt werden k{\"o}nnen. Das Vorgehen erfordert vom Anwender oft ein gewisses Umdenken. Es werden keine Spannungen berechnet, um damit Sicherheit und Lebensdauer zu interpretieren. Statt dessen berechnet man direkt die gesuchte Sicherheit. Der Post-Prozessor wird nur noch zur Modell- und Rechenkontrolle ben{\"o}tigt. Das Vorgehen ist {\"a}nhlich der Stabilit{\"a}tsanalyse (Knicken, Beulen). Durch namhafte industrielle Projektpartner werden Validierung und die Anwendbarkeit auf eine breite Palette technischer Probleme garantiert. Die ebenfalls in LISA geplante Zuverl{\"a}ssigkeitsanalyse ist erst auf der Basis direkter Verfahren effektiv m{\"o}glich. Ohne Traglast- und Einspielanalyse ist plastische Strukturoptimierung auch heute kaum durchf{\"u}hrbar.},
  subject      = {Finite-Elemente-Methode},
  language  = {de}
}
@inproceedings{BohrnStuetzFleischeretal.2012,
  author    = {Bohrn, Ulrich and St{\"u}tz, Evamaria and Fleischer, Maximilian and Sch{\"o}ning, Michael Josef and Wagner, Patrick},
  title     = {Living cell-based gas sensor system for the detection of acetone in air},
  isbn      = {978-3-9813484-2-2},
  doi       = {10.5162/IMCS2012/3.2.3},
  pages     = {269 -- 272},
  year      = {2012},
  language  = {en}
}
@inproceedings{UibelBlass2006,
  author    = {Uibel, Thomas and Blaß, Hans Joachim},
  title     = {Load Carrying Capacity of Joints with Dowel Type Fasteners in Solid Wood Panels},
  series = {Proceedings. CIB-W18 Meeting 2006, Florence, Italy 2006},
  booktitle = {Proceedings. CIB-W18 Meeting 2006, Florence, Italy 2006},
  issn      = {0945-6996},
  pages     = {1 -- 10},
  year      = {2006},
  language  = {en}
}
@inproceedings{DiltheySchleserHeggeretal.2007,
  author    = {Dilthey, Ulrich and Schleser, Markus and Hegger, Josef and Voss, Stefan},
  title     = {Load-bearing behaviour of polymer-impregnated textiles in concrete},
  series = {Fifth International Workshop on High Performance Fiber Reinforced Cement Composites (HPFRCC 5) : Mainz, July 10 - 13, 2007. (RILEM proceedings. 53)},
  booktitle = {Fifth International Workshop on High Performance Fiber Reinforced Cement Composites (HPFRCC 5) : Mainz, July 10 - 13, 2007. (RILEM proceedings. 53)},
  editor    = {Reinhardt, Hans W.},
  publisher = {RILEM Publ.},
  address   = {Bagneux},
  organization    = {International Workshop on High Performance Fiber Reinforced Cement Composites <5, 2007, Mainz>},
  isbn      = {978-2-35158-046-2},
  pages     = {183 -- 192},
  year      = {2007},
  language  = {en}
}
@inproceedings{SchuermannWollert2008,
  author    = {Sch{\"u}rmann, Volker and Wollert, J{\"o}rg},
  title     = {Location based Services in der Geb{\"a}udeautomation},
  series = {Wireless Technologies Kongress 2008: von der Technologie zur Anwendung ; [10. Kongress, 23. - 24. September 2008, Bochum]},
  booktitle = {Wireless Technologies Kongress 2008: von der Technologie zur Anwendung ; [10. Kongress, 23. - 24. September 2008, Bochum]},
  publisher = {Aka},
  address   = {Heidelberg},
  organization    = {Wireless-Technologies-Kongress <10, 2008, Bochum>},
  isbn      = {978-3-89838-608-1},
  pages     = {313 -- 322},
  year      = {2008},
  language  = {de}
}
@inproceedings{BoehmHellmannsBackesetal.2006,
  author    = {B{\"o}hm, Stefan and Hellmanns, Mark and Backes, Andreas and Dilger, Klaus},
  title     = {Lock-in thermography based NDT of automotive parts},
  series = {Proceedings of the 3rd World Congress on Adhesion and Related Phenomena : WCARP-III, October 15 -18, 2006, Beijing, China},
  booktitle = {Proceedings of the 3rd World Congress on Adhesion and Related Phenomena : WCARP-III, October 15 -18, 2006, Beijing, China},
  publisher = {Beijing Adhesion Society of China},
  address   = {Beijing},
  pages     = {382 -- 384},
  year      = {2006},
  language  = {en}
}
@inproceedings{AnthrakidisRusackSchwarzer2010,
  author    = {Anthrakidis, Anette and Rusack, Markus and Schwarzer, Klemens},
  title     = {Low effort measurement method of PTC-efficiency},
  series = {SolarPACES 2010 : the CSP conference: electricity, fuels and clean water from concentrated solar energy ; 21 to 24 September 2010, Perpignan, France},
  booktitle = {SolarPACES 2010 : the CSP conference: electricity, fuels and clean water from concentrated solar energy ; 21 to 24 September 2010, Perpignan, France},
  publisher = {Soc. OSC},
  address   = {Saint Maur},
  pages     = {48 -- 49},
  year      = {2010},
  language  = {en}
}
@inproceedings{FunkeBoernerKeinzetal.2012,
  author    = {Funke, Harald and B{\"o}rner, Sebastian and Keinz, Jan and Hendrick, P. and Recker, E.},
  title     = {Low NOx Hydrogen combustion chamber for industrial gas turbine applications", 14th International Symposium on Transport Phenomena and Dynamics of Rotating Machinery},
  series = {ISROMAC-14 : the Forteenth International Symposium on Transport Phenomena and Dynamics of Rotating Machinery ; Honolulu, Hawaii, February 27 - March 02nd, 2012},
  booktitle = {ISROMAC-14 : the Forteenth International Symposium on Transport Phenomena and Dynamics of Rotating Machinery ; Honolulu, Hawaii, February 27 - March 02nd, 2012},
  year      = {2012},
  language  = {en}
}
@inproceedings{Dachwald2007,
  author    = {Dachwald, Bernd},
  title     = {Low-Thrust Mission Analysis and Global Trajectory Optimization Using Evolutionary Neurocontrol: New Results},
  series = {European Workshop on Space Mission Analysis ESA/ESOC, Darmstadt, Germany 10 { 12 Dec 2007},
  booktitle = {European Workshop on Space Mission Analysis ESA/ESOC, Darmstadt, Germany 10 { 12 Dec 2007},
  year      = {2007},
  abstract  = {Interplanetary trajectories for low-thrust spacecraft are often characterized by multiple revolutions around the sun. Unfortunately, the convergence of traditional trajectory optimizers that are based on numerical optimal control methods depends strongly on an adequate initial guess for the control function (if a direct method is used) or for the starting values of the adjoint vector (if an indirect method is used). Especially when many revolutions around the sun are re- quired, trajectory optimization becomes a very difficult and time-consuming task that involves a lot of experience and expert knowledge in astrodynamics and optimal control theory, because an adequate initial guess is extremely hard to find. Evolutionary neurocontrol (ENC) was proposed as a smart method for low-thrust trajectory optimization that fuses artificial neural networks and evolutionary algorithms to so-called evolutionary neurocontrollers (ENCs) [1]. Inspired by natural archetypes, ENC attacks the trajectoryoptimization problem from the perspective of artificial intelligence and machine learning, a perspective that is quite different from that of optimal control theory. Within the context of ENC, a trajectory is regarded as the result of a spacecraft steering strategy that maps permanently the actual spacecraft state and the actual target state onto the actual spacecraft control vector. This way, the problem of searching the optimal spacecraft trajectory is equivalent to the problem of searching (or "learning") the optimal spacecraft steering strategy. An artificial neural network is used to implement such a spacecraft steering strategy. It can be regarded as a parameterized function (the network function) that is defined by the internal network parameters. Therefore, each distinct set of network parameters defines a different network function and thus a different steering strategy. The problem of searching the optimal steering strategy is now equivalent to the problem of searching the optimal set of network parameters. Evolutionary algorithms that work on a population of (artificial) chromosomes are used to find the optimal network parameters, because the parameters can be easily mapped onto a chromosome. The trajectory optimization problem is solved when the optimal chromosome is found. A comparison of solar sail trajectories that have been published by others [2, 3, 4, 5] with ENC-trajectories has shown that ENCs can be successfully applied for near-globally optimal spacecraft control [1, 6] and that they are able to find trajectories that are closer to the (unknown) global optimum, because they explore the trajectory search space more exhaustively than a human expert can do. The obtained trajectories are fairly accurate with respect to the terminal constraint. If a more accurate trajectory is required, the ENC-solution can be used as an initial guess for a local trajectory optimization method. Using ENC, low-thrust trajectories can be optimized without an initial guess and without expert attendance. Here, new results for nuclear electric spacecraft and for solar sail spacecraft are presented and it will be shown that ENCs find very good trajectories even for very difficult problems. Trajectory optimization results are presented for 1. NASA's Solar Polar Imager Mission, a mission to attain a highly inclined close solar orbit with a solar sail [7] 2. a mission to de ect asteroid Apophis with a solar sail from a retrograde orbit with a very-high velocity impact [8, 9] 3. JPL's \2nd Global Trajectory Optimization Competition", a grand tour to visit four asteroids from different classes with a NEP spacecraft},
  language  = {en}
}
@inproceedings{KuhnhenneFeldmannDoeringetal.2007,
  author    = {Kuhnhenne, Markus and Feldmann, Markus and D{\"o}ring, Bernd and Spranger, Sascha},
  title     = {Luftdichtheit im Stahlleichtbau - Geb{\"a}udeh{\"u}llen in Sandwichbauweise},
  series = {Dichte Geb{\"a}udeh{\"u}lle, Thermografie und Wohnungsl{\"u}ftung : 2. Europ{\"a}isches BlowerDoor-Symposium : 16.3. - 17.3. 2007, Kassel},
  booktitle = {Dichte Geb{\"a}udeh{\"u}lle, Thermografie und Wohnungsl{\"u}ftung : 2. Europ{\"a}isches BlowerDoor-Symposium : 16.3. - 17.3. 2007, Kassel},
  publisher = {Energie + Umwelt-Zentrum},
  organization    = {Europ{\"a}isches BlowerDoor-Symposium <2, 2007, Kassel>},
  pages     = {121 -- 134},
  year      = {2007},
  language  = {de}
}
@inproceedings{HuberRauStreblowetal.2014,
  author    = {Huber, Max and Rau, Sebastian and Streblow, Rita and Wollert, J{\"o}rg and M{\"u}ller, Dirk},
  title     = {L{\"u}ftungskan{\"a}le als Funkstrecke},
  series = {Jahreskolloquium Kommunikation in der Automation (KommA 2014) : Lemgo, 18.11.2014 / J{\"u}rgen Jasperneite ... (Hrsg.)},
  booktitle = {Jahreskolloquium Kommunikation in der Automation (KommA 2014) : Lemgo, 18.11.2014 / J{\"u}rgen Jasperneite ... (Hrsg.)},
  organization    = {Jahreskolloquium Kommunikation in der Automation <5, 2014, Lemgo>},
  isbn      = {978-3-9814062-4-5},
  pages     = {1 -- 8},
  year      = {2014},
  language  = {de}
}
@inproceedings{NikolovskiRekeElsenetal.2021,
  author    = {Nikolovski, Gjorgji and Reke, Michael and Elsen, Ingo and Schiffer, Stefan},
  title     = {Machine learning based 3D object detection for navigation in unstructured environments},
  series = {2021 IEEE Intelligent Vehicles Symposium Workshops (IV Workshops)},
  booktitle = {2021 IEEE Intelligent Vehicles Symposium Workshops (IV Workshops)},
  publisher = {IEEE},
  isbn      = {978-1-6654-7921-9},
  doi       = {10.1109/IVWorkshops54471.2021.9669218},
  pages     = {236 -- 242},
  year      = {2021},
  abstract  = {In this paper we investigate the use of deep neural networks for 3D object detection in uncommon, unstructured environments such as in an open-pit mine. While neural nets are frequently used for object detection in regular autonomous driving applications, more unusual driving scenarios aside street traffic pose additional challenges. For one, the collection of appropriate data sets to train the networks is an issue. For another, testing the performance of trained networks often requires tailored integration with the particular domain as well. While there exist different solutions for these problems in regular autonomous driving, there are only very few approaches that work for special domains just as well. We address both the challenges above in this work. First, we discuss two possible ways of acquiring data for training and evaluation. That is, we evaluate a semi-automated annotation of recorded LIDAR data and we examine synthetic data generation. Using these datasets we train and test different deep neural network for the task of object detection. Second, we propose a possible integration of a ROS2 detector module for an autonomous driving platform. Finally, we present the performance of three state-of-the-art deep neural networks in the domain of 3D object detection on a synthetic dataset and a smaller one containing a characteristic object from an open-pit mine.},
  language  = {en}
}
@inproceedings{GiresiniButenwegAndreinietal.2014,
  author    = {Giresini, Linda and Butenweg, Christoph and Andreini, M. and De Falco, A. and Sassu, M.},
  title     = {Macro-elements identification in historic chapels: the case of St. Venerio Chapel in Reggiolo - Emilia Romagna},
  series = {9th International Conference on Structural Analyses of Historical Conctruction, 14 - 17 October, 2014, Mexico City},
  booktitle = {9th International Conference on Structural Analyses of Historical Conctruction, 14 - 17 October, 2014, Mexico City},
  organization    = {International Conference on Structural Analyses of Historical Conctructions <9, 2014, Mexico City>},
  pages     = {1 -- 12},
  year      = {2014},
  language  = {en}
}
@inproceedings{SimsekKrauseEngelmann2024,
  author    = {Simsek, Beril and Krause, Hans-Joachim and Engelmann, Ulrich M.},
  title     = {Magnetic biosensing with magnetic nanoparticles: Simulative approach to predict signal intensity in frequency mixing magnetic detection},
  series = {4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen},
  booktitle = {4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen},
  editor    = {Digel, Ilya and Staat, Manfred and Trzewik, J{\"u}rgen and Sielemann, Stefanie and Erni, Daniel and Zylka, Waldemar},
  publisher = {Universit{\"a}t Duisburg-Essen},
  address   = {Duisburg},
  organization    = {MedTech Symposium},
  isbn      = {978-3-940402-65-3},
  doi       = {10.17185/duepublico/81475},
  pages     = {27 -- 28},
  year      = {2024},
  abstract  = {Magnetic nanoparticles (MNP) are investigated with great interest for biomedical applications in diagnostics (e.g. imaging: magnetic particle imaging (MPI)), therapeutics (e.g. hyperthermia: magnetic fluid hyperthermia (MFH)) and multi-purpose biosensing (e.g. magnetic immunoassays (MIA)). What all of these applications have in common is that they are based on the unique magnetic relaxation mechanisms of MNP in an alternating magnetic field (AMF). While MFH and MPI are currently the most prominent examples of biomedical applications, here we present results on the relatively new biosensing application of frequency mixing magnetic detection (FMMD) from a simulation perspective. In general, we ask how the key parameters of MNP (core size and magnetic anisotropy) affect the FMMD signal: by varying the core size, we investigate the effect of the magnetic volume per MNP; and by changing the effective magnetic anisotropy, we study the MNPs' flexibility to leave its preferred magnetization direction. From this, we predict the most effective combination of MNP core size and magnetic anisotropy for maximum signal generation.},
  language  = {en}
}