@masterthesis{Breuer2021, type = {Bachelor Thesis}, author = {Breuer, Annika}, title = {Transformativer Designguide: Konzeption eines digitalen Guides f{\"u}r nachhaltige Designentwicklungen}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, year = {2021}, abstract = {Designer entwerfen und gestalten oft, ohne die Gew{\"a}hrleistung von Ressourcen zu ber{\"u}cksichtigen. Nat{\"u}rliche Ressourcen werden im {\"U}bermaß verbraucht. Die Erde kommt mit dem Erneuern nicht mehr hinterher. Der Transformative Designguide ist ein digitaler Leitfaden f{\"u}r nachhaltige Designprozesse, der zu mehr Bewusstsein in der Produktion und im Design f{\"u}hrt, um Ressourcen langfristig einzusparen. Der Guide vermittelt ein umfassendes Bild und liefert alle ben{\"o}tigten Infos auf einen Blick. Das Design des Guides zeigt, dass nachhaltiges Design mehr Qualit{\"a}t durch erh{\"o}htes bewusstes Denken und Seriosit{\"a}t mit sich bringt. Die verschiedenen Herangehensweisen werden in einer einzigartigen 360° Navigation angezeigt. Animierte Grafiken scannen Materialien und Prozesse auf Nachhaltigkeit. Das Design des Guides wirkt dynamisch und sorgt f{\"u}r mehr Aufkl{\"a}rung im Bereich Ressourcenschutz.}, language = {de} } @inproceedings{SchnejiderWisselinkCzarnecki2017, author = {Schnejider, Dominik and Wisselink, Frank and Czarnecki, Christian}, title = {Transformation von Wertsch{\"o}pfungsketten durch das Internet der Dinge - Bewertungsrahmen und Fallstudie}, series = {GI Edition Proceedings Band 275 INFORMATIK 2017}, booktitle = {GI Edition Proceedings Band 275 INFORMATIK 2017}, editor = {Eibl, Maximilian and Gaedke, Martin and Gesellschaft f{\"u}r Informatik e. V. (GI),}, publisher = {K{\"o}llen}, address = {Bonn}, isbn = {978-3-88579-669-5}, issn = {1617-5468}, doi = {10.18420/in2017_208}, pages = {2081 -- 2094}, year = {2017}, abstract = {Momentan finden in vielen Branchen umfassende Ver{\"a}nderungen von M{\"a}rkten und Wertsch{\"o}pfungsketten statt, welche auch als Digitale Transformation bezeichnet werden. In diesem Zusammenhang wird das Internet der Dinge (Internet of Things, IoT) als ein wichtiger technischer Enabler der Ver{\"a}nderungen angesehen. Prim{\"a}re Ziele des IoT sind die Steuerung physischer Gegen-st{\"a}nde aus der Distanz und das Erfassen von Informationen aus dem Umfeld dieser Gegenst{\"a}nde. Welche neuen Gesch{\"a}fts-bzw. Partnermodelle entstehen durch die gemeinsame Nutzung von IoT-Daten und Big-Data-Technologien und welcher qualitative Mehrwert wird dadurch geschaffen? Als Antwort wird in diesem Beitrag ein Bewertungsrahmen zur qualitativen Wertsch{\"o}pfungsanalyse von IoT vorgeschlagen. Anhand dieses Bewertungsrahmens wird ein Anwendungsfall untersucht, der in anonymisierter Form an konkrete Praxisprojekte angelehnt ist. Konkret wird ein Anwendungsfall betrachtet, der eine Abfallwirtschaft 2.0 basierend auf dem Einsatz von IoT vorschl{\"a}gt. Aus den Untersuchungsergebnissen gehen beispielsweise Erkenntnisse hervor, wie Gesch{\"a}ftsmodelle auf Basis eines unentgeltlichen Informationsaustauschs durch IoT gestaltet werden k{\"o}nnen.}, language = {de} } @inproceedings{CzarneckiWinkelmannSpiliopoulou2012, author = {Czarnecki, Christian and Winkelmann, Axel and Spiliopoulou, Myra}, title = {Transformation in Telecommunication - Analyse und Clustering von Real-life Projekten}, series = {Multikonferenz Wirtschaftsinformatik 2012}, booktitle = {Multikonferenz Wirtschaftsinformatik 2012}, editor = {Mattfeld, Dirk Christian and Robra-Bissantz, Susanne}, publisher = {Gito}, address = {Berlin}, isbn = {9783942183635}, pages = {985 -- 998}, year = {2012}, abstract = {Die Ver{\"a}nderungen des Telekommunikationsmarktes haben in der Praxis zu einer Vielzahl von Transformationsprojekten gef{\"u}hrt. Was geh{\"o}rt aber zu einem "Transformationsprojekt", welche Prozesse und Systeme werden ver{\"a}ndert? Zur Beantwortung dieser Frage haben wir 184 Berichte zu Projekten analysiert, die als "Transformationsprojekte" bezeichnet waren. F{\"u}r die Analyse haben wir einen Kodierungsrahmen konzipiert und anhand dessen die Berichte mit einem hierarchischen Clustering-Verfahren in Themen gruppiert. Die Ergebnisse liefern Hinweise {\"u}ber die in der Praxis gesetzten Schwerpunkte und Priorit{\"a}ten. Sie k{\"o}nnen somit als Unterst{\"u}tzung f{\"u}r Unternehmen dienen, die ein Transformationsprojekt planen. Sie weisen zudem darauf hin, in welchen Bereichen eines Unternehmens Unterst{\"u}tzung durch wissenschaftlich erprobte Werkzeuge und Modelle n{\"o}tig ist.}, language = {de} } @article{BongaertsZoschkeWeidneretal.1995, author = {Bongaerts, Johannes and Zoschke, Sascha and Weidner, Uwe and Linden, Gottfried}, title = {Transcriptional regulation of the proton translocating NADH}, series = {Molecular microbiology}, volume = {Vol. 16}, journal = {Molecular microbiology}, number = {Iss. 3}, issn = {1365-2958 (E-Journal); 0950-382x (Print)}, pages = {521 -- 534}, year = {1995}, language = {en} } @article{HalbachScheer2000, author = {Halbach, Thorsten and Scheer, Nico}, title = {Transcriptional activation by the PHD finger is inhibited through an adjacent leucine zipper that binds 14-3-3 proteins}, series = {Nucleic Acids Research}, volume = {28}, journal = {Nucleic Acids Research}, number = {18}, issn = {1362-4962}, doi = {10.1093/nar/28.18.3542}, pages = {3542 -- 3550}, year = {2000}, language = {en} } @article{BodeBartschBoulikasetal.1998, author = {Bode, J. and Bartsch, J. and Boulikas, T. and Iber, M. and Mielke, C. and Sch{\"u}beler, D. and Seibler, Jost and Benham, C.}, title = {Transcription-promoting genomic sites in mammalia: their elucidation and architectural principles}, series = {Gene therapy \& molecular biology}, volume = {1}, journal = {Gene therapy \& molecular biology}, number = {1}, issn = {1529-9120}, pages = {1 -- 29}, year = {1998}, language = {en} } @article{FeichtingerEilmannBuchmannetal.2015, author = {Feichtinger, Linda M. and Eilmann, Britta and Buchmann, Nina and Rigling, Andreas}, title = {Trait-specific responses of Scots pine to irrigation on a short vs long time scale}, series = {Tree Physiology}, volume = {35}, journal = {Tree Physiology}, number = {00}, publisher = {Heron}, address = {Victoria, BC}, issn = {1758-4469 (Online)}, doi = {10.1093/treephys/tpu114}, pages = {1 -- 12}, year = {2015}, language = {en} } @article{WerkhausenCroninAlbrachtetal.2019, author = {Werkhausen, Amelie and Cronin, Neil J. and Albracht, Kirsten and Paulsen, G{\o}ran and Larsen, Askild V. and Bojsen-M{\o}ller, Jens and Seynnes, Olivier R.}, title = {Training-induced increase in Achilles tendon stiffness affects tendon strain pattern during running}, series = {PeerJ}, journal = {PeerJ}, publisher = {Peer}, address = {London}, issn = {21678359}, doi = {10.7717/peerj.6764}, pages = {18 Seiten}, year = {2019}, abstract = {Background During the stance phase of running, the elasticity of the Achilles tendon enables the utilisation of elastic energy and allows beneficial contractile conditions for the triceps surae muscles. However, the effect of changes in tendon mechanical properties induced by chronic loading is still poorly understood. We tested the hypothesis that a training-induced increase in Achilles tendon stiffness would result in reduced tendon strain during the stance phase of running, which would reduce fascicle strains in the triceps surae muscles, particularly in the mono-articular soleus. Methods Eleven subjects were assigned to a training group performing isometric singleleg plantarflexion contractions three times per week for ten weeks, and another ten subjects formed a control group. Before and after the training period, Achilles tendon stiffness was estimated, and muscle-tendon mechanics were assessed during running at preferred speed using ultrasonography, kinematics and kinetics. Results Achilles tendon stiffness increased by 18\% (P <0:01) in the training group, but the associated reduction in strain seen during isometric contractions was not statistically significant. Tendon elongation during the stance phase of running was similar after training, but tendon recoil was reduced by 30\% (P <0:01), while estimated tendon force remained unchanged. Neither gastrocnemius medialis nor soleus fascicle shortening during stance was affected by training. Discussion These results show that a training-induced increase in Achilles tendon stiffness altered tendon behaviour during running. Despite training-induced changes in tendon mechanical properties and recoil behaviour, the data suggest that fascicle shortening patterns were preserved for the running speed that we examined. The asymmetrical changes in tendon strain patterns supports the notion that simple inseries models do not fully explain the mechanical output of the muscle-tendon unit during a complex task like running.}, language = {en} } @inproceedings{KobGoemmelButenwegetal.2006, author = {Kob, Malte and G{\"o}mmel, Andreas and Butenweg, Christoph and Niendorf, Thoralf}, title = {Training of a combined model of larynx and vocal folds with data from MRI measurements}, series = {The 5th International Conference on Voice Physiology and Biomechanics: Variations across Cultures and Species, July 12-14, 2006, Tokyo, Japan. Proceedings}, booktitle = {The 5th International Conference on Voice Physiology and Biomechanics: Variations across Cultures and Species, July 12-14, 2006, Tokyo, Japan. Proceedings}, organization = {International Conference on Voice Physiology and Biomechanics <5, 2006, Tokyo>}, pages = {45 -- 46}, year = {2006}, language = {en} } @inproceedings{SteuerDankert2023, author = {Steuer-Dankert, Linda}, title = {Training future skills - sustainability, interculturality \& innovation in a digital design thinking format}, series = {Proceedings of the 19th International CDIO Conference}, booktitle = {Proceedings of the 19th International CDIO Conference}, pages = {12 Seiten}, year = {2023}, abstract = {The complex questions of today for a world of tomorrow are characterized by their global impact. Solutions must therefore not only be sustainable in the sense of the three pillars of sustainability (economic, environmental, and social) but must also function globally. This goes hand in hand with the need for intercultural acceptance of developed services and products. To achieve this, engineers, as the problem solvers of the future, must be able to work in intercultural teams on appropriate solutions, and be sensitive to intercultural perspectives. To equip the engineers of the future with the so-called future skills, teaching concepts are needed in which students can acquire these methods and competencies in application-oriented formats. The presented course "Applying Design Thinking - Sustainability, Innovation and Interculturality" was developed to teach future skills from the competency areas Digital Key Competencies, Classical Competencies and Transformative Competencies. The CDIO Standard 3.0, in particular the standards 5, 6, 7 and 8, was used as a guideline. The course aims to prepare engineering students from different disciplines and cultures for their future work in an international environment by combining a digital teaching format with an interdisciplinary, transdisciplinary and intercultural setting for solving sustainability challenges. The innovative moment lies in the digital application of design thinking and the inclusion of intercultural as well as trans- and interdisciplinary perspectives in innovation development processes. In this paper, the concept of the course will be presented in detail and the particularities of a digital implementation of design thinking will be addressed. Subsequently, the potentials and challenges will be reflected and practical advice for integrating design thinking in engineering education will be given.}, language = {en} }