@article{WegnervonArxSassKlaassenetal.2013, author = {Wegner, Lena and von Arx, Georg and Sass-Klaassen, Ute G. W. and Eilmann, Britta}, title = {ROXAS - an efficient and accurate tool to detect vessels in diffuse-porous species}, series = {IAWA Journal / International Association of Wood Anatomists}, volume = {34}, journal = {IAWA Journal / International Association of Wood Anatomists}, number = {4}, publisher = {Brill}, address = {Leiden}, issn = {0928-1541 (Print)}, doi = {10.1163/22941932-00000034}, pages = {425 -- 432}, year = {2013}, language = {en} } @article{KuhnertBialonskiNoenningetal.2013, author = {Kuhnert, Marie-Therese and Bialonski, Stephan and Noenning, Nina and Mai, Heinke and Hinrichs, Hermann and Helmstaedter, Christoph and Lehnertz, Klaus}, title = {Incidental and intentional learning of verbal episodic material differentially modifies functional brain networks}, series = {Plos one}, volume = {8}, journal = {Plos one}, number = {11}, publisher = {PLOS}, address = {San Francisco}, doi = {10.1371/journal.pone.0080273}, pages = {e80273}, year = {2013}, abstract = {Learning- and memory-related processes are thought to result from dynamic interactions in large-scale brain networks that include lateral and mesial structures of the temporal lobes. We investigate the impact of incidental and intentional learning of verbal episodic material on functional brain networks that we derive from scalp-EEG recorded continuously from 33 subjects during a neuropsychological test schedule. Analyzing the networks' global statistical properties we observe that intentional but not incidental learning leads to a significantly increased clustering coefficient, and the average shortest path length remains unaffected. Moreover, network modifications correlate with subsequent recall performance: the more pronounced the modifications of the clustering coefficient, the higher the recall performance. Our findings provide novel insights into the relationship between topological aspects of functional brain networks and higher cognitive functions.}, language = {en} } @article{PhamStaat2013, author = {Pham, Phu Tinh and Staat, Manfred}, title = {An Upper Bound Algorithm for Limit and Shakedown Analysis of Bounded Linearly Kinematic Hardening Structures}, series = {Limit State of Materials and Structures : Direct Methods 2. Saxc{\´e}, G{\´e}ry de (Hrsg.)}, journal = {Limit State of Materials and Structures : Direct Methods 2. Saxc{\´e}, G{\´e}ry de (Hrsg.)}, publisher = {Springer}, address = {Dordrecht}, isbn = {978-94-007-5424-9}, pages = {71 -- 87}, year = {2013}, language = {en} } @article{EilmannDobbertinRigling2013, author = {Eilmann, Britta and Dobbertin, Matthias and Rigling, Andreas}, title = {Growth response of Scots pine with different crown transparency status to drought release}, series = {Annals of Forest Science}, volume = {70}, journal = {Annals of Forest Science}, number = {7}, publisher = {Springer}, address = {Cham}, issn = {1286-4560 (Print)}, doi = {10.1007/s13595-013-0310-z}, pages = {685 -- 693}, year = {2013}, language = {en} } @article{BuniatyanHuckPoghossianetal.2013, author = {Buniatyan, V. and Huck, Christina and Poghossian, Arshak and Aroutiounian, V. M. and Sch{\"o}ning, Michael Josef}, title = {BaxSr1-x TiO3/pc-Si heterojunction capacitance}, series = {Armenian journal of physics}, volume = {6}, journal = {Armenian journal of physics}, number = {4}, publisher = {National Academy of Sciences of Armenia}, address = {Yerevan}, issn = {1829-1171}, pages = {188 -- 197}, year = {2013}, language = {en} } @article{BialonskiLehnertz2013, author = {Bialonski, Stephan and Lehnertz, Klaus}, title = {Assortative mixing in functional brain networks during epileptic seizures}, series = {Chaos: An Interdisciplinary Journal of Nonlinear Science}, volume = {23}, journal = {Chaos: An Interdisciplinary Journal of Nonlinear Science}, number = {3}, doi = {10.1063/1.4821915}, pages = {033139}, year = {2013}, language = {en} } @article{IkenAhlbornGerlachetal.2013, author = {Iken, Heiko and Ahlborn, Kristina and Gerlach, Frank and Vonau, Winfried and Zander, Wilhelm and Schubert, J{\"u}rgen P. and Sch{\"o}ning, Michael Josef}, title = {Development of redox glasses and subsequent processing by means of pulsed laser deposition for realizing silicon-based thin-film sensors}, series = {Electrochimica acta}, journal = {Electrochimica acta}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-3859 (E-Journal); 0013-4686 (Print)}, pages = {Available online 30.8.2013}, year = {2013}, language = {en} } @article{StojnicSassKlaassenOrlovicetal.2013, author = {Stojnic, Srdjan and Sass-Klaassen, Ute G. M. and Orlovic, Sasa and Matovic, Bratislav and Eilmann, Britta}, title = {Plastic growth response of European beech provenances to dry site conditions}, volume = {34}, number = {4}, publisher = {Brill}, address = {Leiden}, issn = {0928-1541 (Print)}, doi = {10.1163/22941932-00000038}, pages = {475 -- 484}, year = {2013}, language = {en} } @article{MuribGrinsvenGrietenetal.2013, author = {Murib, M. S. and Grinsven, B. van and Grieten, L. and Janssens, S. D. and Vermeeren, V. and Eersels, K. and Broeders, J. and Ameloot, Marcel and Michiels, L. and Ceuninck, W. De and Haenen, K. and Sch{\"o}ning, Michael Josef and Wagner, Patrick}, title = {Electronic monitoring of chemical DNA denaturation on nanocrystalline diamond electrodes with different molarities and flow rates}, series = {Physica Status Solidi (A). Vol. 210 (2013), iss. 5}, journal = {Physica Status Solidi (A). Vol. 210 (2013), iss. 5}, publisher = {Wiley-VCH}, address = {Berlin}, issn = {0031-8965}, pages = {911 -- 917}, year = {2013}, language = {en} } @article{GraesslRenzHezeletal.2013, author = {Gr{\"a}ßl, Andreas and Renz, Wolfgang and Hezel, Fabian and Dieringer, Matthias A. and Winter, Lukas and {\"O}zerdem, Celal and Rieger, Jan and Kellmann, Peter and Santoro, Davide and Lindel, Tomasz Dawid and Frauenrath, Tobias and Pfeiffer, Harald and Niendorf, Thoralf}, title = {Modular 32-channel transceiver coil array for cardiac MRI at 7.0T}, series = {Magnetic Resonance in Medicine}, volume = {72}, journal = {Magnetic Resonance in Medicine}, number = {1}, publisher = {Wiley-Liss}, address = {New York}, issn = {1522-2594}, doi = {10.1002/mrm.24903}, pages = {276 -- 290}, year = {2013}, abstract = {Purpose To design and evaluate a modular transceiver coil array with 32 independent channels for cardiac MRI at 7.0T. Methods The modular coil array comprises eight independent building blocks, each containing four transceiver loop elements. Numerical simulations were used for B1+ field homogenization and radiofrequency (RF) safety validation. RF characteristics were examined in a phantom study. The array's suitability for accelerated high spatial resolution two-dimensional (2D) FLASH CINE imaging of the heart was examined in a volunteer study. Results Transmission field adjustments and RF characteristics were found to be suitable for the volunteer study. The signal-to-noise intrinsic to 7.0T together with the coil performance afforded a spatial resolution of 1.1 × 1.1 × 2.5 mm3 for 2D CINE FLASH MRI, which is by a factor of 6 superior to standardized CINE protocols used in clinical practice at 1.5T. The 32-channel transceiver array supports one-dimensional acceleration factors of up to R = 4 without impairing image quality significantly. Conclusion The modular 32-channel transceiver cardiac array supports accelerated and high spatial resolution cardiac MRI. The array is compatible with multichannel transmission and provides a technological basis for future clinical assessment of parallel transmission techniques at 7.0T.}, language = {en} } @article{KotliarHanssenEberhardtetal.2013, author = {Kotliar, Konstantin and Hanssen, Henner and Eberhardt, Karla and Vilser, Walthard and Schmaderer, Christoph and Halle, Martin and Heemann, Uwe and Baumann, Marcus}, title = {Retinal pulse wave velocity in young male normotensive and mildly hypertensive subjects}, series = {Microcirculation}, journal = {Microcirculation}, publisher = {Wiley}, address = {Malden}, issn = {1549-8719}, year = {2013}, language = {en} } @article{JensKaldenhoffKirschnerHermannsetal.2014, author = {Jens, Otto and Kaldenhoff, E. and Kirschner-Hermanns, R. and M{\"u}hl, Thomas and Klinge, Uwe}, title = {Elongation of textile pelvic floor implants under load is related to complete loss of effective porosity, thereby favoring incorporation in scar plates}, series = {Journal of biomedical materials research. Part A}, volume = {102}, journal = {Journal of biomedical materials research. Part A}, number = {4}, publisher = {Wiley}, address = {New York}, issn = {1552-4965}, doi = {10.1002/jbm.a.34767}, pages = {1079 -- 1084}, year = {2014}, abstract = {Use of textile structures for reinforcement of pelvic floor structures has to consider mechanical forces to the implant, which are quite different to the tension free conditions of the abdominal wall. Thus, biomechanical analysis of textile devices has to include the impact of strain on stretchability and effective porosity. Prolift® and Prolift + M®, developed for tension free conditions, were tested by measuring stretchability and effective porosity applying mechanical strain. For comparison, we used Dynamesh-PR4®, which was designed for pelvic floor repair to withstand mechanical strain. Prolift® at rest showed moderate porosity with little stretchability but complete loss of effective porosity at strain of 4.9 N/cm. Prolift + M® revealed an increased porosity at rest, but at strain showed high stretchability, with subsequent loss of effective porosity at strain of 2.5 N/cm. Dynamesh PR4® preserved its high porosity even under strain, but as consequence of limited stretchability. Though in tension free conditions Prolift® and Prolift + M® can be considered as large pore class I meshes, application of mechanical strain rapidly lead to collapse of pores. The loss of porosity at mechanical stress can be prevented by constructions with high structural stability. Assessment of porosity under strain was found helpful to define requirements for pelvic floor devices. Clinical studies have to prove whether devices with high porosity as well as high structural stability can improve the patients' outcome.}, language = {en} } @article{WincklerKruegerSchnitzleretal.2014, author = {Winckler, Silvia and Krueger, Rolf and Schnitzler, Thomas and Zang, Werner and Fischer, Rainer and Biselli, Manfred}, title = {A sensitive monitoring system for mammalian cell cultivation processes: a PAT approach}, series = {Bioprocess and biosystems engineering}, volume = {37}, journal = {Bioprocess and biosystems engineering}, number = {5}, publisher = {Springer}, address = {Berlin, Heidelberg}, issn = {1615-7591 (Print) 1615-7605 (Online)}, doi = {10.1007/s00449-013-1062-8}, pages = {901 -- 912}, year = {2014}, abstract = {Biopharmaceuticals such as antibodies are produced in cultivated mammalian cells, which must be monitored to comply with good manufacturing practice. We, therefore, developed a fully automated system comprising a specific exhaust gas analyzer, inline analytics and a corresponding algorithm to precisely determine the oxygen uptake rate, carbon dioxide evolution rate, carbon dioxide transfer rate, transfer quotient and respiratory quotient without interrupting the ongoing cultivation, in order to assess its reproducibility. The system was verified using chemical simulation experiments and was able to measure the respiratory activity of hybridoma cells and DG44 cells (derived from Chinese hamster ovary cells) with satisfactory results at a minimum viable cell density of ~2.0 × 10⁵ cells ml⁻¹. The system was suitable for both batch and fed-batch cultivations in bubble-aerated and membrane-aerated reactors, with and without the control of pH and dissolved oxygen.}, language = {en} } @article{BandodkarMolinnusMirzaetal.2014, author = {Bandodkar, Amay J. and Molinnus, Denise and Mirza, Omar and Guinovart, Tomas and Windmiller, Joshua R. and Valdes-Ramirez, Gabriela and Andrade, Francisco J. and Sch{\"o}ning, Michael Josef and Wang, Joseph}, title = {Epidermal tattoo potentiometric sodium sensors with wireless signal transduction for continuous non-invasive sweat monitoring}, series = {Biosensors and bioelectronics}, volume = {54}, journal = {Biosensors and bioelectronics}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-4235 (E-Journal); 0956-5663 (Print)}, doi = {10.1016/j.bios.2013.11.039}, pages = {603 -- 609}, year = {2014}, abstract = {This article describes the fabrication, characterization and application of an epidermal temporary-transfer tattoo-based potentiometric sensor, coupled with a miniaturized wearable wireless transceiver, for real-time monitoring of sodium in the human perspiration. Sodium excreted during perspiration is an excellent marker for electrolyte imbalance and provides valuable information regarding an individual's physical and mental wellbeing. The realization of the new skin-worn non-invasive tattoo-like sensing device has been realized by amalgamating several state-of-the-art thick film, laser printing, solid-state potentiometry, fluidics and wireless technologies. The resulting tattoo-based potentiometric sodium sensor displays a rapid near-Nernstian response with negligible carryover effects, and good resiliency against various mechanical deformations experienced by the human epidermis. On-body testing of the tattoo sensor coupled to a wireless transceiver during exercise activity demonstrated its ability to continuously monitor sweat sodium dynamics. The real-time sweat sodium concentration was transmitted wirelessly via a body-worn transceiver from the sodium tattoo sensor to a notebook while the subjects perspired on a stationary cycle. The favorable analytical performance along with the wearable nature of the wireless transceiver makes the new epidermal potentiometric sensing system attractive for continuous monitoring the sodium dynamics in human perspiration during diverse activities relevant to the healthcare, fitness, military, healthcare and skin-care domains.}, language = {en} } @article{Dikta2014, author = {Dikta, Gerhard}, title = {Asymptotically efficient estimation under semi-parametric random censorship models}, series = {Journal of multivariate analysis}, volume = {124}, journal = {Journal of multivariate analysis}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1095-7243 (E-Journal); 0047-259X (Print)}, doi = {10.1016/j.jmva.2013.10.002}, pages = {10 -- 24}, year = {2014}, abstract = {We study the estimation of some linear functionals which are based on an unknown lifetime distribution. The observations are assumed to be generated under the semi-parametric random censorship model (SRCM), that is, a random censorship model where the conditional expectation of the censoring indicator given the observation belongs to a parametric family. Under this setup a semi-parametric estimator of the survival function was introduced by the author. If the parametric model assumption is correct, it is known that the estimated functional which is based on this semi-parametric estimator is asymptotically at least as efficient as the corresponding one which rests on the nonparametric Kaplan-Meier estimator. In this paper we show that the estimated functional which is based on this semi-parametric estimator is asymptotically efficient with respect to the class of all regular estimators under this semi-parametric model.}, language = {en} } @article{HeinzeMangPeteretal.2014, author = {Heinze, Daniel and Mang, Thomas and Peter, Karin and M{\"o}ller, Martin and Weichold, Oliver}, title = {Synthesis of low molecular weight poly(vinyl acetate) and its application as plasticizer}, series = {Journal of applied polymer science}, volume = {131}, journal = {Journal of applied polymer science}, number = {9}, publisher = {Wiley}, address = {New York}, issn = {1097-4628 (E-Journal); 0021-8995 (Print)}, doi = {10.1002/app.40226}, pages = {Article No. 40226}, year = {2014}, abstract = {Poly(vinyl acetate), PVAc, with a degree of polymerization Xn = 10 was prepared by chain-transfer radical polymerization using carbon tetrachloride and used as oligomeric plasticizer for commercial PVAc. However, the chlorinated chain ends cause a low thermal stability requiring mild Cl/H substitution. The product exhibits high thermal stability and excellent melt-compounding properties. Blends of oligomeric and commercial PVAc show single glass transition temperatures which decrease with higher oligomer content and exhibit small negative deviations from Fox' linear additivity rule. This indicates plasticization and miscibility being mainly due to entropic effects. Injection-moulded thick specimens show ductile behaviour at oligomer contents >10 wt \%, while sheets with a thickness of 0.2-0.5 mm appear flexible already at 7.5 wt \%. The oxygen permeability coefficients are an order of magnitude lower than those of low-density polyethylene. Due to the sum of their properties, the plasticized sheets present a promising alternative in the preparation of barrier materials.}, language = {en} } @article{WangDruckenmuellerElbersetal.2014, author = {Wang, Ren-Qi and Druckenm{\"u}ller, Katharina and Elbers, Gereon and Guenther, Klaus and Crou{\´e}, Jean-Philippe}, title = {Analysis of aquatic-phase natural organic matter by optimized LDI-MS method}, series = {Journal of mass spectrometry}, volume = {49}, journal = {Journal of mass spectrometry}, number = {2}, publisher = {Wiley}, address = {Bognor Regis}, issn = {1096-9888}, doi = {10.1002/jms.3321}, pages = {154 -- 160}, year = {2014}, abstract = {The composition and physiochemical properties of aquatic-phase natural organic matter (NOM) are most important problems for both environmental studies and water industry. Laser desorption/ionization (LDI) mass spectrometry facilitated successful examinations of NOM, as humic and fulvic acids in NOM are readily ionized by the nitrogen laser. In this study, hydrophobic NOMs (HPO NOMs) from river, reservoir and waste water were characterized by this technique. The effect of analytical variables like concentration, solvent composition and laser energy was investigated. The exact masses of small molecular NOM moieties in the range of 200-1200 m/z were determined in reflectron mode. In addition, spectra of post-source-decay experiments in this range showed that some compounds from different natural NOMs had the same fragmental ions. In the large mass range of 1200-15 000 Da, macromolecules and their aggregates were found in HPO NOMs from natural waters. Highly humic HPO exhibited mass peaks larger than 8000 Da. On the other hand, the waste water and reservoir water mainly had relatively smaller molecules of about 2000 Da. The LDI-MS measurements indicated that highly humic river waters were able to form large aggregates and membrane foulants, while the HPO NOMs from waste water and reservoir water were unlikely to form large aggregates. Copyright © 2014 John Wiley \& Sons, Ltd.}, language = {en} } @article{SawadaNakazawaTakenagaetal.2014, author = {Sawada, Kazuaki and Nakazawa, Hirokazu and Takenaga, Shoko and Hizawa, Takeshi and Futagawa, Masato and Dasai, Fumihiro and Sakurai, Takashi and Okumura, Koichi and Hattori, Toshiaki and Ishida, Makoto}, title = {Multimodal bioimage sensor}, series = {IEICE transactions on fundamentals of electronics, communidations and computer sciences}, volume = {E97-A (2014)}, journal = {IEICE transactions on fundamentals of electronics, communidations and computer sciences}, number = {3}, publisher = {IEICE}, address = {Tokyo}, issn = {0916-8508 (Print) ; 1745-1337 (Online)}, doi = {10.1587/transfun.E97.A.726}, pages = {726 -- 733}, year = {2014}, abstract = {To visualize the biochemical distribution two-dimensionally, we invented a solid-state-type ion image sensor that indicates the chemical activity of solutions and cells. The device, which consists of a CCD array covered with a functionalized membrane to detect charge accumulation, is highly sensitive to changes in the concentration and two-dimensional distribution of ions and biomaterials.}, language = {en} } @article{HeineHerrmannSelmeretal.2014, author = {Heine, A. and Herrmann, G. and Selmer, Thorsten and Terwesten, F. and Buckel, W. and Reuter, K.}, title = {High resolution crystal structure of clostridium propionicum β-Alanyl-CoA:Ammonia Lyase, a new member of the "Hot Dog Fold" protein superfamily}, series = {Proteins}, volume = {82}, journal = {Proteins}, number = {9}, publisher = {Wiley-Liss}, address = {New York}, issn = {1097-0134 (E-Journal); 0887-3585 (Print)}, doi = {10.1002/prot.24557}, pages = {2041 -- 2053}, year = {2014}, abstract = {Clostridium propionicum is the only organism known to ferment β-alanine, a constituent of coenzyme A (CoA) and the phosphopantetheinyl prosthetic group of holo-acyl carrier protein. The first step in the fermentation is a CoA-transfer to β-alanine. Subsequently, the resulting β-alanyl-CoA is deaminated by the enzyme β-alanyl-CoA:ammonia lyase (Acl) to reversibly form ammonia and acrylyl-CoA. We have determined the crystal structure of Acl in its apo-form at a resolution of 0.97 {\AA} as well as in complex with CoA at a resolution of 1.59 {\AA}. The structures reveal that the enyzme belongs to a superfamily of proteins exhibiting a so called "hot dog fold" which is characterized by a five-stranded antiparallel β-sheet with a long α-helix packed against it. The functional unit of all "hot dog fold" proteins is a homodimer containing two equivalent substrate binding sites which are established by the dimer interface. In the case of Acl, three functional dimers combine to a homohexamer strongly resembling the homohexamer formed by YciA-like acyl-CoA thioesterases. Here, we propose an enzymatic mechanism based on the crystal structure of the Acl·CoA complex and molecular docking. Proteins 2014; 82:2041-2053. © 2014 Wiley Periodicals, Inc.}, language = {en} } @article{TakenagaBiselliSchnitzleretal.2014, author = {Takenaga, Shoko and Biselli, Manfred and Schnitzler, Thomas and {\"O}hlschl{\"a}ger, Peter and Wagner, Torsten and Sch{\"o}ning, Michael Josef}, title = {Toward multi-analyte bioarray sensors: LAPS-based on-chip determination of a Michaelis-Menten-like kinetics for cell culturing}, series = {Physica status solidi A : Applications and materials science}, volume = {211}, journal = {Physica status solidi A : Applications and materials science}, number = {6}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1521-396X (E); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)}, doi = {10.1002/pssa.201330464}, pages = {1410 -- 1415}, year = {2014}, abstract = {The metabolic activity of Chinese hamster ovary (CHO) cells was observed using a light-addressable potentiometric sensor (LAPS). The dependency toward different glucose concentrations (17-200 mM) follows a Michaelis-Menten kinetics trajectory with Kₘ = 32.8 mM, and the obtained Kₘ value in this experiment was compared with that found in literature. In addition, the pH shift induced by glucose metabolism of tumor cells transfected with the HPV-16 genome (C3 cells) was successfully observed. These results indicate the possibility to determine the tumor cells metabolism with a LAPS-based measurement device.}, language = {en} }