@article{HonarvarfardGamellaPoghossianetal.2017, author = {Honarvarfard, Elham and Gamella, Maria and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Katz, Evgeny}, title = {An enzyme-based reversible Controlled NOT (CNOT) logic gate operating on a semiconductor transducer}, series = {Applied Materials Today}, volume = {9}, journal = {Applied Materials Today}, publisher = {Elsevier}, address = {Amsterdam}, issn = {2352-9407}, doi = {10.1016/j.apmt.2017.08.003}, pages = {266 -- 270}, year = {2017}, abstract = {An enzyme-based biocatalytic system mimicking operation of a logically reversible Controlled NOT (CNOT) gate has been interfaced with semiconductor electronic transducers. Electrolyte-insulator-semiconductor (EIS) structures have been used to transduce chemical changes produced by the enzyme system to an electronically readable capacitive output signal using field-effect features of the EIS device. Two enzymes, urease and esterase, were immobilized on the insulating interface of EIS structure producing local pH changes performing XOR logic operation controlled by various combinations of the input signals represented by urea and ethyl butyrate. Another EIS transducer was functionalized with esterase only, thus performing Identity (ID) logic operation for the ethyl butyrate input. Both semiconductor devices assembled in parallel operated as a logically reversible CNOT gate. The present system, despite its simplicity, demonstrated for the first time logically reversible function of the enzyme system transduced electronically with the semiconductor devices. The biomolecular realization of a CNOT gate interfaced with semiconductors is promising for integration into complex biomolecular networks and future biosensor/biomedical applications.}, language = {en} } @incollection{SteuerDankertBouffierGaedickeetal.2017, author = {Steuer-Dankert, Linda and Bouffier, Anna and Gaedicke, Sonja and Leicht-Scholten, Carmen}, title = {Diversifying engineering education: a transdisciplinary approach from RWTH Aachen University}, series = {Strategies for increasing diversity in engineering majors and careers}, booktitle = {Strategies for increasing diversity in engineering majors and careers}, publisher = {IGI Global}, address = {Hershey, USA}, isbn = {9781522522126}, doi = {10.4018/978-1-5225-2212-6.ch010}, pages = {201 -- 235}, year = {2017}, abstract = {Engineers and therefore engineering education are challenged by the increasing complexity of questions to be answered globally. The education of future engineers therefore has to answer with curriculums that build up relevant skills. This chapter will give an example how to bring engineering and social responsibility successful together to build engineers of tomorrow. Through the integration of gender and diversity perspectives, engineering research and teaching is expanded with new perspectives and contents providing an important potential for innovation. Aiming on the enhancement of engineering education with distinctive competencies beyond technical expertise, the teaching approach introduced in the chapter represents key factors to ensure that coming generations of engineers will be able to meet the requirements and challenges a changing globalized world holds for them. The chapter will describe how this approach successfully has been implemented in the curriculum in engineering of a leading technical university in Germany.}, language = {en} } @inproceedings{SchoppHeuermannMarso2017, author = {Schopp, Christoph and Heuermann, Holger and Marso, Michel}, title = {Multiphysical Study of an Atmospheric Microwave Argon Plasma Jet}, series = {IEEE Transactions on Plasma Science}, volume = {45}, booktitle = {IEEE Transactions on Plasma Science}, number = {6}, publisher = {IEEE}, issn = {1939-9375}, doi = {10.1109/TPS.2017.2692735}, pages = {932 -- 937}, year = {2017}, language = {en} } @article{GamellaZakharchenkoGuzetal.2017, author = {Gamella, Maria and Zakharchenko, Andrey and Guz, Nataliia and Masi, Madeline and Minko, Sergiy and Kolpashchikov, Dmitry M. and Iken, Heiko and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Katz, Evgeny}, title = {DNA computing system activated by electrochemically triggered DNA realease from a polymer-brush-modified electrode array}, series = {Electroanalysis}, volume = {29}, journal = {Electroanalysis}, number = {2}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1521-4109}, doi = {10.1002/elan.201600389}, pages = {398 -- 408}, year = {2017}, abstract = {An array of four independently wired indium tin oxide (ITO) electrodes was used for electrochemically stimulated DNA release and activation of DNA-based Identity, AND and XOR logic gates. Single-stranded DNA molecules were loaded on the mixed poly(N,N-dimethylaminoethyl methacrylate) (PDMAEMA)/poly(methacrylic acid) (PMAA) brush covalently attached to the ITO electrodes. The DNA deposition was performed at pH 5.0 when the polymer brush is positively charged due to protonation of tertiary amino groups in PDMAEMA, thus resulting in electrostatic attraction of the negatively charged DNA. By applying electrolysis at -1.0 V(vs. Ag/AgCl reference) electrochemical oxygen reduction resulted in the consumption of hydrogen ions and local pH increase near the electrode surface. The process resulted in recharging the polymer brush to the negative state due to dissociation of carboxylic groups of PMAA, thus repulsing the negatively charged DNA and releasing it from the electrode surface. The DNA release was performed in various combinations from different electrodes in the array assembly. The released DNA operated as input signals for activation of the Boolean logic gates. The developed system represents a step forward in DNA computing, combining for the first time DNA chemical processes with electronic input signals.}, language = {en} } @article{MolinnusPoghossianKeusgenetal.2017, author = {Molinnus, Denise and Poghossian, Arshak and Keusgen, Michael and Katz, Evgeny and Sch{\"o}ning, Michael Josef}, title = {Coupling of Biomolecular Logic Gates with Electronic Transducers: From Single Enzyme Logic Gates to Sense/Act/Treat Chips}, series = {Electroanalysis}, volume = {29}, journal = {Electroanalysis}, number = {8}, publisher = {Wiley}, address = {Weinheim}, issn = {1521-4109}, doi = {10.1002/elan.201700208}, pages = {1840 -- 1849}, year = {2017}, abstract = {The integration of biomolecular logic principles with electronic transducers allows designing novel digital biosensors with direct electrical output, logically triggered drug-release, and closed-loop sense/act/treat systems. This opens new opportunities for advanced personalized medicine in the context of theranostics. In the present work, we will discuss selected examples of recent developments in the field of interfacing enzyme logic gates with electrodes and semiconductor field-effect devices. Special attention is given to an enzyme OR/Reset logic gate based on a capacitive field-effect electrolyte-insulator-semiconductor sensor modified with a multi-enzyme membrane. Further examples are a digital adrenaline biosensor based on an AND logic gate with binary YES/NO output and an integrated closed-loop sense/act/treat system comprising an amperometric glucose sensor, a hydrogel actuator, and an insulin (drug) sensor.}, language = {en} } @incollection{HerrmannKearneyRoegeretal.2017, author = {Herrmann, Ulf and Kearney, D. and R{\"o}ger, M. and Prahl, C.}, title = {System performance measurements}, series = {The Performance of Concentrated Solar Power (CSP) Systems : Modelling, Measurement and Assessment}, booktitle = {The Performance of Concentrated Solar Power (CSP) Systems : Modelling, Measurement and Assessment}, publisher = {Woodhead Publishing}, address = {Duxford}, isbn = {978-0-08-100448-7}, doi = {https://doi.org/10.1016/B978-0-08-100447-0.00005-5}, pages = {115 -- 165}, year = {2017}, abstract = {This chapter introduces performance and acceptance testing and describes state-of-the-art tools, methods, and instruments to assess the plant performance or realize plant acceptance testing. The status of the development of standards for performance assessment is given.}, language = {en} } @inproceedings{JabbariBhattaraiAndingetal.2017, author = {Jabbari, Medisa and Bhattarai, Aroj and Anding, Ralf and Staat, Manfred}, title = {Biomechanical simulation of different prosthetic meshes for repairing uterine/vaginal vault prolapse}, series = {2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West}, booktitle = {2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West}, editor = {Erni, Daniel and Fischerauer, Alice and Himmel, J{\"o}rg and Seeger, Thomas and Thelen, Klaus}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-9814801-9-1}, doi = {10.17185/duepublico/43984}, pages = {118 -- 119}, year = {2017}, language = {en} } @inproceedings{SuryoputriGhaderiLinderetal.2017, author = {Suryoputri, Nathania and Ghaderi, Aydin and Linder, Peter and Kotliar, Konstantin and G{\"o}ttler, Jens and Sorg, Christian and Grimmer, Timo}, title = {Does hemodynamic response function change in Alzheimer disease?}, series = {2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West}, booktitle = {2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West}, editor = {Erni, Daniel and Fischerauer, Alice and Himmel, J{\"o}rg and Seeger, Thomas and Thelen, Klaus}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-9814801-9-1}, doi = {10.17185/duepublico/43984}, pages = {92}, year = {2017}, language = {en} } @inproceedings{ThurnBalcGebhardtetal.2017, author = {Thurn, Laura and Balc, Nicolae and Gebhardt, Andreas and Kessler, Julia}, title = {Education packed in technology to promote innovations: Teaching Additive Manufacturing based on a rolling Lab}, series = {Modern Technologies in Manufacturing (MTeM 2017 - AMaTUC)}, booktitle = {Modern Technologies in Manufacturing (MTeM 2017 - AMaTUC)}, issn = {2261-236X}, doi = {10.1051/matecconf/201713702013}, pages = {6 Seiten}, year = {2017}, language = {en} } @book{LabischWaehlisch2017, author = {Labisch, Susanna and W{\"a}hlisch, Georg}, title = {Technisches Zeichnen: Eigenst{\"a}ndig lernen und effektiv {\"u}ben}, edition = {5. Aufl.}, publisher = {Springer Fachmedien}, address = {Wiesbaden}, isbn = {978-3-658-18313-4}, doi = {10.1007/978-3-658-18313-4}, pages = {XI, 300 S. 291 Abb., 50 Abb. in Farbe}, year = {2017}, language = {de} } @incollection{Fabo2017, author = {Fabo, Sabine}, title = {K{\"u}nstlerische Interventionen im {\"o}ffentlichen Raum}, series = {Die Experimentalstadt : Kreativit{\"a}t und die kulturelle Dimension der Nachhaltigen Entwicklung / Julia-Lena Reinermann, Friederike Behr (Hrsg.)}, booktitle = {Die Experimentalstadt : Kreativit{\"a}t und die kulturelle Dimension der Nachhaltigen Entwicklung / Julia-Lena Reinermann, Friederike Behr (Hrsg.)}, publisher = {Springer Fachmedien}, address = {Wiesbaden}, isbn = {978-3-658-14980-2 (Print)}, pages = {201 -- 217}, year = {2017}, abstract = {K{\"u}nstlerische Einlassungen auf den {\"o}ffentlichen Raum folgten lange Zeit dem Prinzip des subkulturellen Widerstands. Nur in dem strategischen, invasiven Akt der Intervention sah man noch die M{\"o}glichkeit einer weitgreifenden Kritik am kulturellen System. Begriffe wie Cultural Hacking, Guerilla Marketing, Adbusting, Konsumguerilla oder parasit{\"a}re Strategien pr{\"a}gten eine rebellische Auffassung der k{\"u}nstlerischen Einmischung. Gleichzeitig konnten diese Haltungen aufgrund ihres rebellischen Chics m{\"u}helos von dem, was sie kritisierten, aufgenommen und vereinnahmt werden. K{\"u}nstlerisches Handeln verharrt jedoch nicht in der Pose des Widerst{\"a}ndigen, sondern arbeitet kontinuierlich an der Problematisierung und Gestaltung der {\"o}ffentlichen Wahrnehmung. Viele Interventionen der Gegenwartskunst weisen unterschiedliche Grade der {\"A}sthetisierung, der Partizipation und der Kooperation in der Auseinandersetzung mit dem {\"o}ffentlichen Raum auf. Das wache Agieren im urbanen Kontext, die Irritation von Erwartungshaltungen, Fake und Desillusionierungsarbeit verstehen sich als k{\"u}nstlerische Arbeit an der Sensibilisierung der Wahrnehmung.}, language = {de} } @inproceedings{JablonskiKochBronderetal.2017, author = {Jablonski, Melanie and Koch, Claudia and Bronder, Thomas and Poghossian, Arshak and Wege, Christina and Sch{\"o}ning, Michael Josef}, title = {Field-Effect Biosensors Modified with Tobacco Mosaic Virus Nanotubes as Enzyme Nanocarrier}, series = {MDPI Proceeding}, volume = {1}, booktitle = {MDPI Proceeding}, number = {4}, doi = {10.3390/proceedings1040505}, pages = {4}, year = {2017}, language = {en} } @inproceedings{SchleupenEngemannBagherietal.2017, author = {Schleupen, Josef and Engemann, Heiko and Bagheri, Mohsen and Kallweit, Stephan and Dahmann, Peter}, title = {Developing a climbing maintenance robot for tower and rotor blade service of wind turbines}, series = {Advances in Robot Design and Intelligent Control : Proceedings of the 25th Conference on Robotics in Alpe-Adria-Danube Region (RAAD16)}, booktitle = {Advances in Robot Design and Intelligent Control : Proceedings of the 25th Conference on Robotics in Alpe-Adria-Danube Region (RAAD16)}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-49058-8}, doi = {10.1007/978-3-319-49058-8_34}, pages = {310 -- 319}, year = {2017}, language = {en} } @incollection{PoghossianSchoening2017, author = {Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Nanomaterial-Modified Capacitive Field-Effect Biosensors}, series = {Springer Series on Chemical Sensors and Biosensors (Methods and Applications)}, booktitle = {Springer Series on Chemical Sensors and Biosensors (Methods and Applications)}, publisher = {Springer}, address = {Berlin, Heidelberg}, doi = {10.1007/5346_2017_2}, pages = {1 -- 25}, year = {2017}, abstract = {The coupling of charged molecules, nanoparticles, and more generally, inorganic/organic nanohybrids with semiconductor field-effect devices based on an electrolyte-insulator-semiconductor (EIS) system represents a very promising strategy for the active tuning of electrochemical properties of these devices and, thus, opening new opportunities for label-free biosensing by the intrinsic charge of molecules. The simplest field-effect sensor is a capacitive EIS sensor, which represents a (bio-)chemically sensitive capacitor. In this chapter, selected examples of recent developments in the field of label-free biosensing using nanomaterial-modified capacitive EIS sensors are summarized. In the first part, we present applications of EIS sensors modified with negatively charged gold nanoparticles for the label-free electrostatic detection of positively charged small proteins and macromolecules, for monitoring the layer-by-layer formation of oppositely charged polyelectrolyte (PE) multilayers as well as for the development of an enzyme-based biomolecular logic gate. In the second part, examples of a label-free detection by means of EIS sensors modified with a positively charged weak PE layer are demonstrated. These include electrical detection of on-chip and in-solution hybridized DNA (deoxyribonucleic acid) as well as an EIS sensor with pH-responsive weak PE/enzyme multilayers for enhanced field-effect biosensing.}, language = {en} } @inproceedings{SchneiderAlHakimKayseretal.2017, author = {Schneider, Oliver and Al Hakim, Taher and Kayser, Peter and Digel, Ilya}, title = {Development and trials of a test chamber for ultrasound-assisted sampling of living cells from solid surfaces}, series = {2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West}, booktitle = {2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West}, editor = {Erni, Daniel and Fischerauer, Alice and Himmel, J{\"o}rg and Seeger, Thomas and Thelen, Klaus}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-9814801-9-1}, doi = {10.17185/duepublico/43984}, pages = {96 -- 97}, year = {2017}, language = {en} } @article{KatzPoghossianSchoening2017, author = {Katz, Evgeny and Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Enzyme-based logic gates and circuits - analytical applications and interfacing with electronics}, series = {Analytical and Bioanalytical Chemistry}, volume = {409}, journal = {Analytical and Bioanalytical Chemistry}, publisher = {Springer}, address = {Berlin}, issn = {1618-2650}, doi = {10.1007/s00216-016-0079-7}, pages = {81 -- 94}, year = {2017}, abstract = {The paper is an overview of enzyme-based logic gates and their short circuits, with specific examples of Boolean AND and OR gates, and concatenated logic gates composed of multi-step enzyme-biocatalyzed reactions. Noise formation in the biocatalytic reactions and its decrease by adding a "filter" system, converting convex to sigmoid response function, are discussed. Despite the fact that the enzyme-based logic gates are primarily considered as components of future biomolecular computing systems, their biosensing applications are promising for immediate practical use. Analytical use of the enzyme logic systems in biomedical and forensic applications is discussed and exemplified with the logic analysis of biomarkers of various injuries, e.g., liver injury, and with analysis of biomarkers characteristic of different ethnicity found in blood samples on a crime scene. Interfacing of enzyme logic systems with modified electrodes and semiconductor devices is discussed, giving particular attention to the interfaces functionalized with signal-responsive materials. Future perspectives in the design of the biomolecular logic systems and their applications are discussed in the conclusion.}, language = {en} } @article{Laack2017, author = {Laack, Walter van}, title = {Neurophysiologisch ist das nicht alles zu erkl{\"a}ren : Nahtoderfahrungen aus wissenschaftlicher Sicht}, series = {Der Allgemeinarzt}, volume = {38}, journal = {Der Allgemeinarzt}, number = {1}, publisher = {Universimed Deutschland GmbH}, address = {Mainz}, issn = {0172-7249}, pages = {4 -- 7}, year = {2017}, language = {de} } @inproceedings{MarcoFerrein2017, author = {Marco, Heather G. and Ferrein, Alexander}, title = {AGNES: The African-German Network of Excellence in Science}, series = {Proceedings of the 2nd Developing World Robotics Forum, Workshop at IEEE AFRICON 2017}, booktitle = {Proceedings of the 2nd Developing World Robotics Forum, Workshop at IEEE AFRICON 2017}, pages = {1 -- 2}, year = {2017}, language = {en} } @inproceedings{CarzanaDachwaldNoomen2017, author = {Carzana, Livio and Dachwald, Bernd and Noomen, Ron}, title = {Model and trajectory optimization for an ideal laser-enhanced solar sail}, series = {68th International Astronautical Congress}, booktitle = {68th International Astronautical Congress}, year = {2017}, abstract = {A laser-enhanced solar sail is a solar sail that is not solely propelled by solar radiation but additionally by a laser beam that illuminates the sail. This way, the propulsive acceleration of the sail results from the combined action of the solar and the laser radiation pressure onto the sail. The potential source of the laser beam is a laser satellite that coverts solar power (in the inner solar system) or nuclear power (in the outer solar system) into laser power. Such a laser satellite (or many of them) can orbit anywhere in the solar system and its optimal orbit (or their optimal orbits) for a given mission is a subject for future research. This contribution provides the model for an ideal laser-enhanced solar sail and investigates how a laser can enhance the thrusting capability of such a sail. The term "ideal" means that the solar sail is assumed to be perfectly reflecting and that the laser beam is assumed to have a constant areal power density over the whole sail area. Since a laser beam has a limited divergence, it can provide radiation pressure at much larger solar distances and increase the radiation pressure force into the desired direction. Therefore, laser-enhanced solar sails may make missions feasible, that would otherwise have prohibitively long flight times, e.g. rendezvous missions in the outer solar system. This contribution will also analyze exemplary mission scenarios and present optimial trajectories without laying too much emphasis on the design and operations of the laser satellites. If the mission studies conclude that laser-enhanced solar sails would have advantages with respect to "traditional" solar sails, a detailed study of the laser satellites and the whole system architecture would be the second next step}, language = {en} } @inproceedings{SchildtBraunMarcocca2017, author = {Schildt, P. and Braun, Carsten and Marcocca, P.}, title = {Flight testing the extra 330LE flying testbed}, series = {48th Annual International Symposium of the Society of Flight Test Engineers 2017}, booktitle = {48th Annual International Symposium of the Society of Flight Test Engineers 2017}, isbn = {978-151085387-4}, pages = {349 -- 362}, year = {2017}, language = {en} }