@article{KraemerPitaZhouetal.2009, author = {Kr{\"a}mer, Melina and Pita, Marcos and Zhou, Jian and Ornatska, Maryna and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Katz, Evgeny}, title = {Coupling of Biocomputing Systems with Electronic Chips: Electronic Interface for Transduction of Biochemical Information}, series = {Journal of Physical Chemistry C: Nanomaterials and Interfaces. 113 (2009), H. 6}, journal = {Journal of Physical Chemistry C: Nanomaterials and Interfaces. 113 (2009), H. 6}, publisher = {American Cemical Society}, address = {Washington, DC}, isbn = {1932-7455}, pages = {2573 -- 2579}, year = {2009}, language = {en} } @article{HuckJollyWagneretal.2011, author = {Huck, Christina and Jolly, Christina and Wagner, Patrick and Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {One-chip integrated dual amperometric/field-effect sensor for the detection of dissolved hydrogen}, series = {Procedia Engineering. 25 (2011)}, journal = {Procedia Engineering. 25 (2011)}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {1877-7058}, pages = {1161 -- 1164}, year = {2011}, language = {en} } @article{Fabo1992, author = {Fabo, Sabine}, title = {Roaratorio : John Cage}, series = {Diagonal : Zeitschrift der Universit{\"a}t Siegen}, volume = {4(1992)}, journal = {Diagonal : Zeitschrift der Universit{\"a}t Siegen}, number = {Heft "Experimente"}, address = {Siegen}, isbn = {0938-7161}, pages = {201 -- 210}, year = {1992}, language = {de} } @article{WuBronderPoghossianetal.2014, author = {Wu, Chunsheng and Bronder, Thomas and Poghossian, Arshak and Werner, Frederik and B{\"a}cker, Matthias and Sch{\"o}ning, Michael Josef}, title = {Label-free electrical detection of DNA with a multi-spot LAPS: First step towards light-addressable DNA chips}, series = {Physica status solidi A : Applications and materials science}, volume = {211}, journal = {Physica status solidi A : Applications and materials science}, number = {6}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)}, doi = {10.1002/pssa.201330442}, pages = {1423 -- 1428}, year = {2014}, abstract = {A multi-spot (4 × 4 spots) light-addressable potentiometric sensor (MLAPS) consisting of an Al-p-Si-SiO2 structure has been applied for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge for the first time. Single-stranded probe ssDNA molecules (20 bases) were covalently immobilized onto the silanized SiO2 gate surface. The unspecific adsorption of mismatch ssDNA on the MLAPS gate surface was blocked by bovine serum albumin molecules. To reduce the screening effect and to achieve a high sensor signal, the measurements were performed in a low ionic-strength solution. The photocurrent-voltage (I-V) curves were simultaneously recorded on all 16 spots after each surface functionalization step. Large shifts of I-V curves of 25 mV were registered after the DNA immobilization and hybridization event. In contrast, a small potential shift (∼5 mV) was observed in case of mismatch ssDNA, revealing good specificity of the sensor. The obtained results demonstrate the potential of the MLAPS as promising transducer platform for the multi-spot label-free electrical detection of DNA molecules by their intrinsic molecular charge.}, language = {en} } @article{FerreinFritzLakemeyer2004, author = {Ferrein, Alexander and Fritz, Christian and Lakemeyer, Gerhard}, title = {On-Line Decision-Theoretic Golog for Unpredictable Domains / Ferrein, Alexander ; Fritz, Christian ; Lakemeyer, Gerhard}, series = {KI 2004: Advances in Artificial Intelligence : 27th Annual German Conference on AI, KI 2004, Ulm, Germany, September 20-24, 2004. Proceedings}, journal = {KI 2004: Advances in Artificial Intelligence : 27th Annual German Conference on AI, KI 2004, Ulm, Germany, September 20-24, 2004. Proceedings}, publisher = {Springer}, address = {Berlin}, pages = {322 -- 336}, year = {2004}, language = {en} } @article{StaatHeitzer2000, author = {Staat, Manfred and Heitzer, M.}, title = {Traglastanalyse - ein strukturmechanisches Verfahren zur Beurteilung von gerissenen Bauteilen und Verbindungen}, series = {Festigkeits- und Bruchverhalten von F{\"u}geverbindungen : 32. Tagung des DVM-Arbeitskreises Bruchvorg{\"a}nge ; 22. und 23. Februar 2000 in Berlin / Richard, H. A. [Hrsg]}, journal = {Festigkeits- und Bruchverhalten von F{\"u}geverbindungen : 32. Tagung des DVM-Arbeitskreises Bruchvorg{\"a}nge ; 22. und 23. Februar 2000 in Berlin / Richard, H. A. [Hrsg]}, publisher = {Deutscher Verband f{\"u}r Materialforschung und -pr{\"u}fung}, address = {Berlin}, pages = {183 -- 192}, year = {2000}, language = {de} } @article{LaackCasser1989, author = {Laack, Walter van and Casser, H.-R.}, title = {Arthroskopische Behandlung der Osteochondrosis dissecans an der medialen Femurrolle}, series = {Arthroskopie. 2 (1989), H. 1}, journal = {Arthroskopie. 2 (1989), H. 1}, isbn = {0933-7946}, pages = {16 -- 18}, year = {1989}, language = {de} } @article{PoghossianJablonskiMolinnusetal.2020, author = {Poghossian, Arshak and Jablonski, Melanie and Molinnus, Denise and Wege, Christina and Sch{\"o}ning, Michael Josef}, title = {Field-Effect Sensors for Virus Detection: From Ebola to SARS-CoV-2 and Plant Viral Enhancers}, series = {Frontiers in Plant Science}, volume = {11}, journal = {Frontiers in Plant Science}, number = {Article 598103}, publisher = {Frontiers}, address = {Lausanne}, doi = {10.3389/fpls.2020.598103}, pages = {1 -- 14}, year = {2020}, abstract = {Coronavirus disease 2019 (COVID-19) is a novel human infectious disease provoked by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, no specific vaccines or drugs against COVID-19 are available. Therefore, early diagnosis and treatment are essential in order to slow the virus spread and to contain the disease outbreak. Hence, new diagnostic tests and devices for virus detection in clinical samples that are faster, more accurate and reliable, easier and cost-efficient than existing ones are needed. Due to the small sizes, fast response time, label-free operation without the need for expensive and time-consuming labeling steps, the possibility of real-time and multiplexed measurements, robustness and portability (point-of-care and on-site testing), biosensors based on semiconductor field-effect devices (FEDs) are one of the most attractive platforms for an electrical detection of charged biomolecules and bioparticles by their intrinsic charge. In this review, recent advances and key developments in the field of label-free detection of viruses (including plant viruses) with various types of FEDs are presented. In recent years, however, certain plant viruses have also attracted additional interest for biosensor layouts: Their repetitive protein subunits arranged at nanometric spacing can be employed for coupling functional molecules. If used as adapters on sensor chip surfaces, they allow an efficient immobilization of analyte-specific recognition and detector elements such as antibodies and enzymes at highest surface densities. The display on plant viral bionanoparticles may also lead to long-time stabilization of sensor molecules upon repeated uses and has the potential to increase sensor performance substantially, compared to conventional layouts. This has been demonstrated in different proof-of-concept biosensor devices. Therefore, richly available plant viral particles, non-pathogenic for animals or humans, might gain novel importance if applied in receptor layers of FEDs. These perspectives are explained and discussed with regard to future detection strategies for COVID-19 and related viral diseases.}, language = {en} } @article{BialonskiHorstmannLehnertz2010, author = {Bialonski, Stephan and Horstmann, Marie-Therese and Lehnertz, Klaus}, title = {From brain to earth and climate systems: Small-world interaction networks or not?}, series = {Chaos: An Interdisciplinary Journal of Nonlinear Science}, volume = {20}, journal = {Chaos: An Interdisciplinary Journal of Nonlinear Science}, number = {1}, publisher = {AIP Publishing}, address = {Melville, NY}, issn = {1089-7682}, doi = {10.1063/1.3360561}, pages = {013134}, year = {2010}, abstract = {We consider recent reports on small-world topologies of interaction networks derived from the dynamics of spatially extended systems that are investigated in diverse scientific fields such as neurosciences, geophysics, or meteorology. With numerical simulations that mimic typical experimental situations, we have identified an important constraint when characterizing such networks: indications of a small-world topology can be expected solely due to the spatial sampling of the system along with the commonly used time series analysis based approaches to network characterization.}, language = {en} } @article{LaackHennesRefisch1987, author = {Laack, Walter van and Hennes, A. and Refisch, A.}, title = {Narkosemobilisation der Schultersteife (Periarthritis humeroscapularis ankylosans)}, series = {Zeitschrift f{\"u}r Orthop{\"a}die und Ihre Grenzgebiete. 125 (1987), H. 6}, journal = {Zeitschrift f{\"u}r Orthop{\"a}die und Ihre Grenzgebiete. 125 (1987), H. 6}, isbn = {0044-3220}, pages = {669 -- 673}, year = {1987}, language = {de} } @article{Heuermann1995, author = {Heuermann, Holger}, title = {Selbstkalibrierverfahren zur Systemfehlerkorrektur von Streuparametermessungen auf Halbleitersubstraten}, series = {Mikrowellen und Optronik : Kongreßunterlagen = Microwaves and optronics / MIOP '95, 8. Kongreßmesse f{\"u}r Hochfrequenztechnik, Messehalle Sindelfingen, 30. Mai - 1. Juni 1995. [Hrsg.: Network GmbH]}, journal = {Mikrowellen und Optronik : Kongreßunterlagen = Microwaves and optronics / MIOP '95, 8. Kongreßmesse f{\"u}r Hochfrequenztechnik, Messehalle Sindelfingen, 30. Mai - 1. Juni 1995. [Hrsg.: Network GmbH]}, address = {Hagenburg}, isbn = {3-924651-45-0}, pages = {23 -- 29}, year = {1995}, language = {de} } @article{HeuermannGraf1996, author = {Heuermann, Holger and Graf, W.}, title = {Vergleich mehrerer Naeherungsverfahren zur Berechnung des Wellenwiderstandes von Mikrostreifenleitungen mit experimentellen Ergebnissen}, series = {Kleinheubacher Berichte : Vortr{\"a}ge und Berichte der gemeinsamen Tagung des U.R.S.I.-Landesausschusses in der Bundesrepublik Deutschland / Hrsg.: Deutsche Telekom AG. 39. 1996 (1996)}, journal = {Kleinheubacher Berichte : Vortr{\"a}ge und Berichte der gemeinsamen Tagung des U.R.S.I.-Landesausschusses in der Bundesrepublik Deutschland / Hrsg.: Deutsche Telekom AG. 39. 1996 (1996)}, year = {1996}, language = {de} } @article{HeuermannSchiek1994, author = {Heuermann, Holger and Schiek, Burkhard}, title = {Sichere on-wafer-Streuparameter-Messungen mit Selbstkalibrierverfahren}, series = {Kleinheubacher Berichte : Vortr{\"a}ge und Berichte der gemeinsamen Tagung des U.R.S.I.-Landesausschusses in der Bundesrepublik Deutschland / Hrsg.: Deutsche Telekom AG. 38. 1994 (1994)}, journal = {Kleinheubacher Berichte : Vortr{\"a}ge und Berichte der gemeinsamen Tagung des U.R.S.I.-Landesausschusses in der Bundesrepublik Deutschland / Hrsg.: Deutsche Telekom AG. 38. 1994 (1994)}, pages = {611 -- 622}, year = {1994}, language = {de} } @article{Weigand2000, author = {Weigand, Christoph}, title = {Economically Optimal Adaptive Inspection Policies}, series = {Economic Quality Control. 15 (2000), H. 1/2}, journal = {Economic Quality Control. 15 (2000), H. 1/2}, isbn = {0940-5151}, pages = {55 -- 77}, year = {2000}, language = {en} } @article{ThielMufflerTippkoetteretal.2015, author = {Thiel, Alexander and Muffler, Kai and Tippk{\"o}tter, Nils and Suck, Kirstin and Sohling, Ulrich and Ruf, Friedrich and Ulber, Roland}, title = {Aufarbeitung von Polyphenolen aus Weizen mittels Zeolithen am Beispiel der Ferulas{\"a}ure}, series = {Chemie IngenieurTechnik}, volume = {87}, journal = {Chemie IngenieurTechnik}, number = {1-2}, publisher = {Wiley}, address = {Weinheim}, doi = {10.1002/cite.201400031}, pages = {128 -- 136}, year = {2015}, abstract = {Aufarbeitung von Polyphenolen aus Weizenmittels Zeolithen am Beispiel der Ferulasa¨ ureAlexander Thiel1, Kai Muffler1, Nils Tippko¨ tter1, Kirstin Suck2, Ulrich Sohling2, Friedrich Ruf3und Roland Ulber1,*DOI: 10.1002/cite.201400031Bei der Ferulasa¨ure handelt es sich um einen Wertstoff, der aus Weizen gewonnen und in der Lebensmittel- und Pharma-industrie eingesetzt werden kann. Der Einsatz von Weizen als nachwachsende Rohstoffquelle ist allerdings nur dann wirt-schaftlich durchfu¨hrbar, wenn eine Prozessintegration in die bestehenden industriellen Verfahren gewa¨hrleistet oder einedirekte Konkurrenz zur Mehl- und Sta¨rkeindustrie vermieden werden kann. In diesem Artikel wird ein Verfahren aufge-zeigt, welches hohe Ausbeuten ermo¨glicht und eine Konkurrenz zu bestehenden Verwertungspfaden vermeidet.}, language = {de} } @article{AlKaidyDuweHusteretal.2015, author = {Al-Kaidy, Huschyar and Duwe, Anna and Huster, Manuel and Muffler, Kai and Schlegel, Christin and Tim, Sieker and Stadtm{\"u}ller, Ralf and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {Biotechnology and bioprocess engineering - from the first ullmann's article to recent trends}, series = {ChemBioEng Reviews}, volume = {2}, journal = {ChemBioEng Reviews}, number = {3}, publisher = {Wiley}, address = {Weinheim}, doi = {10.1002/cben.201500008}, pages = {175 -- 184}, year = {2015}, abstract = {For several thousand years, biotechnology and its associated technical processes have had a great impact on the development of mankind. Based on empirical methods, in particular for the production of foodstuffs and daily commodities, these disciplines have become one of the most innovative future issues. Due to the increasing detailed understanding of cellular processes, production strains can now be optimized. In combination with modern bioprocesses, a variety of bulk and fine chemicals as well as pharmaceuticals can be produced efficiently. In this article, some of the current trends in biotechnology are discussed.}, language = {en} } @article{SchindlerBialonskiHorstmannetal.2008, author = {Schindler, Kaspar A. and Bialonski, Stephan and Horstmann, Marie-Therese and Elger, Christian E. and Lehnertz, Klaus}, title = {Evolving functional network properties and synchronizability during human epileptic seizures}, series = {Chaos: An Interdisciplinary Journal of Nonlinear Science}, volume = {18}, journal = {Chaos: An Interdisciplinary Journal of Nonlinear Science}, number = {3}, issn = {1089-7682}, doi = {10.1063/1.2966112}, pages = {033119}, year = {2008}, language = {en} } @article{Weigand1993, author = {Weigand, Christoph}, title = {On the Effects of SPC on Production Time}, series = {Economic Quality Control. 8 (1993)}, journal = {Economic Quality Control. 8 (1993)}, isbn = {0940-5151}, pages = {23 -- 61}, year = {1993}, language = {en} } @article{HeuermannEmmrichBongartz2022, author = {Heuermann, Holger and Emmrich, Thomas and Bongartz, Simon}, title = {Microwave spark plug to support ignitions with high compression ratios}, series = {IEEE Transactions on Plasma Science}, journal = {IEEE Transactions on Plasma Science}, number = {Early Access}, publisher = {IEEE}, issn = {1939-9375}, doi = {10.1109/TPS.2022.3183690}, pages = {1 -- 6}, year = {2022}, abstract = {Upcoming gasoline engines should run with a larger number of fuels beginning from petrol over methanol up to gas by a wide range of compression ratios and a homogeneous charge. In this article, the microwave (MW) spark plug, based on a high-speed frequency hopping system, is introduced as a solution, which can support a nitrogen compression ratio up to 1:39 in a chamber and more. First, an overview of the high-speed frequency hopping MW ignition and operation system as well as the large number of applications are presented. Both gives an understanding of this new base technology for MW plasma generation. Focus of the theoretical part is the explanation of the internal construction of the spark plug, on the achievable of the high voltage generation as well as the high efficiency to hold the plasma. In detail, the development process starting with circuit simulations and ending with the numerical multiphysics field simulations is described. The concept is evaluated with a reference prototype covering the frequency range between 2.40 and 2.48 GHz and working over a large power range from 20 to 200 W. A larger number of different measurements starting by vector hot-S11 measurements and ending by combined working scenarios out of hot temperature, high pressure and charge motion are winding up the article. The limits for the successful pressure tests were given by the pressure chamber. Pressures ranged from 1 to 39 bar and charge motion up to 25 m/s as well as temperatures from 30◦ to 125◦.}, language = {en} } @article{SchusserLeinhosBaeckeretal.2013, author = {Schusser, Sebastian and Leinhos, Marcel and B{\"a}cker, Matthias and Poghossian, Arshak and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Impedance spectroscopy: A tool for real-time in situ monitoring of the degradation of biopolymers}, series = {Physica Status Solidi (A)}, volume = {210}, journal = {Physica Status Solidi (A)}, number = {5}, publisher = {Wiley}, address = {Weinheim}, issn = {1521-396X ; 0031-8965}, doi = {10.1002/pssa.201200941}, pages = {905 -- 910}, year = {2013}, abstract = {Investigation of the degradation kinetics of biodegradable polymers is essential for the development of implantable biomedical devices with predicted biodegradability. In this work, an impedimetric sensor has been applied for real-time and in situ monitoring of degradation processes of biopolymers. The sensor consists of two platinum thin-film electrodes covered by a polymer film to be studied. The benchmark biomedical polymer poly(D,L-lactic acid) (PDLLA) was used as a model system. PDLLA films were deposited on the sensor structure from a polymer solution by using the spin-coating method. The degradation kinetics of PDLLA films have been studied in alkaline solutions of pH 9 and 12 by means of an impedance spectroscopy (IS) method. Any changes in a polymer capacitance/resistance induced by water uptake and/or polymer degradation will modulate the global impedance of the polymer-covered sensor that can be used as an indicator of the polymer degradation. The degradation rate can be evaluated from the time-dependent impedance spectra. As expected, a faster degradation has been observed for PDLLA films exposed to pH 12 solution.}, language = {en} }