@article{MoraisSumanSchoeningetal.2023,
  author    = {Morais, Paulo V. and Suman, Pedro H. and Sch{\"o}ning, Michael Josef and Siqueira Junior, Jos{\´e} R. and Orlandi, Marcelo O.},
  title     = {Layer-by-layer film based on Sn₃O₄ nanobelts as sensing units to detect heavy metals using a capacitive field-effect sensor platform},
  series = {Chemosensors},
  volume    = {11},
  journal   = {Chemosensors},
  number    = {8},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2227-9040},
  doi       = {10.3390/chemosensors11080436},
  pages     = {Artikel 436},
  year      = {2023},
  abstract  = {Lead and nickel, as heavy metals, are still used in industrial processes, and are classified as "environmental health hazards" due to their toxicity and polluting potential. The detection of heavy metals can prevent environmental pollution at toxic levels that are critical to human health. In this sense, the electrolyte-insulator-semiconductor (EIS) field-effect sensor is an attractive sensing platform concerning the fabrication of reusable and robust sensors to detect such substances. This study is aimed to fabricate a sensing unit on an EIS device based on Sn₃O₄ nanobelts embedded in a polyelectrolyte matrix of polyvinylpyrrolidone (PVP) and polyacrylic acid (PAA) using the layer-by-layer (LbL) technique. The EIS-Sn₃O₄ sensor exhibited enhanced electrochemical performance for detecting Pb²⁺ and Ni²⁺ ions, revealing a higher affinity for Pb²⁺ ions, with sensitivities of ca. 25.8 mV/decade and 2.4 mV/decade, respectively. Such results indicate that Sn₃O₄ nanobelts can contemplate a feasible proof-of-concept capacitive field-effect sensor for heavy metal detection, envisaging other future studies focusing on environmental monitoring.},
  language  = {en}
}
@article{WeldenJablonskiWegeetal.2021,
  author    = {Welden, Rene and Jablonski, Melanie and Wege, Christina and Keusgen, Michael and Wagner, Patrick Hermann and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Light-Addressable Actuator-Sensor Platform for Monitoring and Manipulation of pH Gradients in Microfluidics: A Case Study with the Enzyme Penicillinase},
  series = {Biosensors},
  volume    = {11},
  journal   = {Biosensors},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2079-6374},
  doi       = {10.3390/bios11060171},
  pages     = {Artikel 171},
  year      = {2021},
  abstract  = {The feasibility of light-addressed detection and manipulation of pH gradients inside an electrochemical microfluidic cell was studied. Local pH changes, induced by a light-addressable electrode (LAE), were detected using a light-addressable potentiometric sensor (LAPS) with different measurement modes representing an actuator-sensor system. Biosensor functionality was examined depending on locally induced pH gradients with the help of the model enzyme penicillinase, which had been immobilized in the microfluidic channel. The surface morphology of the LAE and enzyme-functionalized LAPS was studied by scanning electron microscopy. Furthermore, the penicillin sensitivity of the LAPS inside the microfluidic channel was determined with regard to the analyte's pH influence on the enzymatic reaction rate. In a final experiment, the LAE-controlled pH inhibition of the enzyme activity was monitored by the LAPS.},
  language  = {en}
}
@article{WeldenSchoeningWagneretal.2020,
  author    = {Welden, Rene and Sch{\"o}ning, Michael Josef and Wagner, Patrick H. and Wagner, Torsten},
  title     = {Light-Addressable Electrodes for Dynamic and Flexible Addressing of Biological Systems and Electrochemical Reactions},
  series = {Sensors},
  volume    = {20},
  journal   = {Sensors},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s20061680},
  pages     = {Artikel 1680},
  year      = {2020},
  abstract  = {In this review article, we are going to present an overview on possible applications of light-addressable electrodes (LAE) as actuator/manipulation devices besides classical electrode structures. For LAEs, the electrode material consists of a semiconductor. Illumination with a light source with the appropiate wavelength leads to the generation of electron-hole pairs which can be utilized for further photoelectrochemical reaction. Due to recent progress in light-projection technologies, highly dynamic and flexible illumination patterns can be generated, opening new possibilities for light-addressable electrodes. A short introduction on semiconductor-electrolyte interfaces with light stimulation is given together with electrode-design approaches. Towards applications, the stimulation of cells with different electrode materials and fabrication designs is explained, followed by analyte-manipulation strategies and spatially resolved photoelectrochemical deposition of different material types.},
  language  = {en}
}
@article{WagnerVornholtWerneretal.2016,
  author    = {Wagner, Torsten and Vornholt, Wolfgang and Werner, Frederik and Yoshinobu, Tatsuo and Miyamoto, Ko-Ichiro and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Light-addressable potentiometric sensor (LAPS) combined with magnetic beads for pharmaceutical screening},
  series = {Physics in medicine},
  volume    = {2016},
  journal   = {Physics in medicine},
  number    = {1},
  issn      = {2352-4510},
  doi       = {10.1016/j.phmed.2016.03.001},
  pages     = {2 -- 7},
  year      = {2016},
  abstract  = {The light-addressable potentiometric sensor (LAPS) has the unique feature to address different regions of a sensor surface without the need of complex structures. Measurements at different locations on the sensor surface can be performed in a common analyte solution, which distinctly simplifies the fluidic set-up. However, the measurement in a single analyte chamber prevents the application of different drugs or different concentrations of a drug to each measurement spot at the same time as in the case of multi-reservoir-based set-ups. In this work, the authors designed a LAPS-based set-up for cell culture screening that utilises magnetic beads loaded with the endotoxin (lipopolysaccharides, LPS), to generate a spatially distributed gradient of analyte concentration. Different external magnetic fields can be adjusted to move the magnetic beads loaded with a specific drug within the measurement cell. By recording the metabolic activities of a cell layer cultured on top of the LAPS surface, this work shows the possibility to apply different concentrations of a sample along the LAPS measurement spots within a common analyte solution.},
  language  = {en}
}
@article{DantismTakenagaWagneretal.2015,
  author    = {Dantism, S. and Takenaga, S. and Wagner, P. and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Light-addressable Potentiometric Sensor (LAPS) Combined with Multi-chamber Structures to Investigate the Metabolic Activity of Cells},
  series = {Procedia Engineering},
  volume    = {120},
  journal   = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2015.08.647},
  pages     = {384 -- 387},
  year      = {2015},
  abstract  = {LAPS are field-effect-based potentiometric sensors which are able to monitor analyte concentrations in a spatially resolved manner. Hence, a LAPS sensor system is a powerful device to record chemical imaging of the concentration of chemical species in an aqueous solution, chemical reactions, or the growth of cell colonies on the sensor surface, to record chemical images. In this work, multi-chamber 3D-printed structures made out of polymer (PP-ABS) were combined with LAPS chips to analyse differentially and simultaneously the metabolic activity of Escherichia coli K12 and Chinese hamster ovary (CHO) cells, and the responds of those cells to the addition of glucose solution.},
  language  = {en}
}
@article{MiyamotoSatoAbeetal.2016,
  author    = {Miyamoto, Ko-Ichiro and Sato, Takuya and Abe, Minami and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo},
  title     = {Light-addressable potentiometric sensor as a sensing element in plug-based microfluidic devices},
  series = {Micromachines},
  volume    = {7},
  journal   = {Micromachines},
  number    = {7},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2072-666X},
  doi       = {10.3390/mi7070111},
  pages     = {111},
  year      = {2016},
  abstract  = {A plug-based microfluidic system based on the principle of the light-addressable potentiometric sensor (LAPS) is proposed. The LAPS is a semiconductor-based chemical sensor, which has a free addressability of the measurement point on the sensing surface. By combining a microfluidic device and LAPS, ion sensing can be performed anywhere inside the microfluidic channel. In this study, the sample solution to be measured was introduced into the channel in a form of a plug with a volume in the range of microliters. Taking advantage of the light-addressability, the position of the plug could be monitored and pneumatically controlled. With the developed system, the pH value of a plug with a volume down to 400 nL could be measured. As an example of plug-based operation, two plugs were merged in the channel, and the pH change was detected by differential measurement.},
  language  = {en}
}
@article{YoshinobuSchoening2021,
  author    = {Yoshinobu, Tatsuo and Sch{\"o}ning, Michael Josef},
  title     = {Light-addressable potentiometric sensors (LAPS) for cell monitoring and biosensing},
  series = {Current Opinion in Electrochemistry},
  journal   = {Current Opinion in Electrochemistry},
  number    = {In Press, Journal Pre-proof},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2451-9103},
  doi       = {10.1016/j.coelec.2021.100727},
  year      = {2021},
  language  = {en}
}
@article{WagnerSchoening2007,
  author    = {Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Light-addressable potentiometric sensors (LAPS): recent trends and applications},
  series = {Electrochemical sensor analysis / edited by S. Alegret ...},
  journal   = {Electrochemical sensor analysis / edited by S. Alegret ...},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {978-0-444-53053-0},
  pages     = {87 -- 128},
  year      = {2007},
  language  = {en}
}
@article{WagnerShigiaharaMiyamotoetal.2012,
  author    = {Wagner, Torsten and Shigiahara, N. and Miyamoto, K. and Suzurikawa, J. and Finger, F. and Sch{\"o}ning, Michael Josef and Yoshinobu, T.},
  title     = {Light-addressable Potentiometric Sensors and Light-addressable Electrodes as a Combined Sensor-and-manipulator Microsystem with High Flexibility},
  series = {Procedia Engineering},
  journal   = {Procedia Engineering},
  number    = {47},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2012.09.290},
  pages     = {890 -- 893},
  year      = {2012},
  abstract  = {This work describes the novel combination of the light-addressable electrode (LAE) and the light-addressable potentiometric sensor (LAPS) into a microsystem set-up. Both the LAE as well as the LAPS shares the principle of addressing the active spot by means of a light beam. This enables both systems to manipulate resp. to detect an analyte with a high spatial resolution. Hence, combining both principles into a single set-up enables the active stimulation e.g., by means of electrolysis and a simultaneous observation e.g., the response of an entrapped biological cell by detection of extracellular pH changes. The work will describe the principles of both technologies and the necessary steps to integrate them into a single set-up. Furthermore, examples of application and operation of such systems will be presented.},
  language  = {en}
}
@article{YoshinobuMiyamotoWerneretal.2017,
  author    = {Yoshinobu, Tatsuo and Miyamoto, Ko-ichiro and Werner, Frederik and Poghossian, Arshak and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Light-addressable potentiometric sensors for quantitative spatial imaging of chemical species},
  series = {Annual Review of Analytical Chemistry},
  volume    = {10},
  journal   = {Annual Review of Analytical Chemistry},
  publisher = {Annual Reviews},
  address   = {Palo Alto, Calif.},
  issn      = {1936-1327},
  doi       = {10.1146/annurev-anchem-061516-045158},
  pages     = {225 -- 246},
  year      = {2017},
  abstract  = {A light-addressable potentiometric sensor (LAPS) is a semiconductor-based chemical sensor, in which a measurement site on the sensing surface is defined by illumination. This light addressability can be applied to visualize the spatial distribution of pH or the concentration of a specific chemical species, with potential applications in the fields of chemistry, materials science, biology, and medicine. In this review, the features of this chemical imaging sensor technology are compared with those of other technologies. Instrumentation, principles of operation, and various measurement modes of chemical imaging sensor systems are described. The review discusses and summarizes state-of-the-art technologies, especially with regard to the spatial resolution and measurement speed; for example, a high spatial resolution in a submicron range and a readout speed in the range of several tens of thousands of pixels per second have been achieved with the LAPS. The possibility of combining this technology with microfluidic devices and other potential future developments are discussed.},
  language  = {en}
}
@article{BreuerRaueKirschbaumetal.2015,
  author    = {Breuer, Lars and Raue, Markus and Kirschbaum, M. and Mang, Thomas and Sch{\"o}ning, Michael Josef and Thoelen, R. and Wagner, Torsten},
  title     = {Light-controllable polymeric material based on temperature-sensitive hydrogels with incorporated graphene oxide},
  series = {Physica status solidi (a)},
  volume    = {212},
  journal   = {Physica status solidi (a)},
  number    = {6},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201431944},
  pages     = {1368 -- 1374},
  year      = {2015},
  abstract  = {Poly(N-isopropylacrylamide) (PNIPAAm) hydrogel films with incorporated graphene oxide (GO) were developed and tested as light-stimulated actuators. GO dispersions were synthesized via Hummers method and characterized toward their optical properties and photothermal energy conversion. The hydrogels were prepared by means of photopolymerization. In addition, the influence of GO within the hydrogel network on the lower critical solution temperature (LCST) was investigated by differential scanning calorimetry (DSC). The optical absorbance and the response to illumination were determined as a function of GO concentration for thin hydrogel films. A proof of principle for the stimulation with light was performed.},
  language  = {en}
}
@article{SchuetzWeissbeckerSchrothetal.2001,
  author    = {Sch{\"u}tz, S. and Weißbecker, G. and Schroth, P. and Sch{\"o}ning, Michael Josef},
  title     = {Linkage of inanimate structures to biological systems - smart materials in biological micro- nanosystems},
  series = {Smart materials : proceedings of the 1st Caesarium, Bonn, November 17 - 19, 1999 / Karl-Heinz Hoffmann ed.},
  journal   = {Smart materials : proceedings of the 1st Caesarium, Bonn, November 17 - 19, 1999 / Karl-Heinz Hoffmann ed.},
  publisher = {Springer},
  address   = {Berlin [u.a.]},
  isbn      = {3-540-67957-X},
  pages     = {149 -- 157},
  year      = {2001},
  language  = {en}
}
@article{ErmelenkoYoshinobuMourzinaetal.2002,
  author    = {Ermelenko, Y. and Yoshinobu, T. and Mourzina, Y. and Furuichi, K. and Levichev, S. and Vlasov, Y. and Sch{\"o}ning, Michael Josef and Iwasaki, H.},
  title     = {Lithium sensor based on the laser scanning semiconductor transducer},
  series = {Analytica Chimica Acta. 459 (2002), H. 1},
  journal   = {Analytica Chimica Acta. 459 (2002), H. 1},
  issn      = {0378-4304},
  pages     = {1 -- 9},
  year      = {2002},
  language  = {en}
}
@article{GasparyanPoghossianVitusevichetal.2009,
  author    = {Gasparyan, F. V. and Poghossian, Arshak and Vitusevich, S. A. and Petrychuk, M. V. and Sydoruk, V. A. and Surmalyan, A. V. and Siqueira, J. R. and Oliveira, O. N. and Offenh{\"a}usser, A. and Sch{\"o}ning, Michael Josef},
  title     = {Low Frequency Noise In Electrolyte-Gate Field-Effect Devices Functionalized With Dendrimer/Carbon-Nanotube Multilayers},
  series = {Noise and fluctuations : 20th International Conference on Noise and Fluctuations, ICNF 2009, Pisa, Italy, 14 - 19 June 2009 / ed. Massimo Macucci; Giovanni Basso},
  journal   = {Noise and fluctuations : 20th International Conference on Noise and Fluctuations, ICNF 2009, Pisa, Italy, 14 - 19 June 2009 / ed. Massimo Macucci; Giovanni Basso},
  publisher = {American Inst. of Physics},
  address   = {Melville, NY},
  isbn      = {9780735406650},
  pages     = {133 -- 136},
  year      = {2009},
  language  = {en}
}
@article{GasparyanPoghossianVitusevichetal.2011,
  author    = {Gasparyan, Ferdinand V. and Poghossian, Arshak and Vitusevich, Svetlana A. and Petrychuk, Mykhaylo V. and Sydoruk, Viktor A. and Siqueira, Jos{\´e} R. Jr. and Oliveira, Osvaldo N. Jr. and Offenh{\"a}usser, Andreas and Sch{\"o}ning, Michael Josef},
  title     = {Low-Frequency Noise in Field-Effect Devices Functionalized With Dendrimer/Carbon-Nanotube Multilayers},
  series = {IEEE Sensors Journal. 11 (2011), H. 1},
  journal   = {IEEE Sensors Journal. 11 (2011), H. 1},
  publisher = {IEEE},
  address   = {New York},
  isbn      = {1530-437X},
  pages     = {142 -- 149},
  year      = {2011},
  language  = {en}
}
@article{SchoeningPoghossianSchultze2003,
  author    = {Sch{\"o}ning, Michael Josef and Poghossian, Arshak and Schultze, Joachim W.},
  title     = {Measuring seven parameters by two ISFET modules in a microcell set-up},
  series = {Int. Journal of Computational Engineering Science. 4 (2003), H. 2},
  journal   = {Int. Journal of Computational Engineering Science. 4 (2003), H. 2},
  isbn      = {1465-8763},
  pages     = {257 -- 260},
  year      = {2003},
  language  = {en}
}
@article{HuckSchiffelsHerreraetal.2013,
  author    = {Huck, Christina and Schiffels, Johannes and Herrera, Cony N. and Schelden, Maximilian and Selmer, Thorsten and Poghossian, Arshak and Baumann, Marcus and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Metabolic responses of Escherichia coli upon glucose pulses captured by a capacitive field-effect sensor},
  series = {Physica Status Solidi (A)},
  volume    = {210},
  journal   = {Physica Status Solidi (A)},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {0031-8965},
  doi       = {10.1002/pssa.201200900},
  pages     = {926 -- 931},
  year      = {2013},
  abstract  = {Living cells are complex biological systems transforming metabolites taken up from the surrounding medium. Monitoring the responses of such cells to certain substrate concentrations is a challenging task and offers possibilities to gain insight into the vitality of a community influenced by the growth environment. Cell-based sensors represent a promising platform for monitoring the metabolic activity and thus, the "welfare" of relevant organisms. In the present study, metabolic responses of the model bacterium Escherichia coli in suspension, layered onto a capacitive field-effect structure, were examined to pulses of glucose in the concentration range between 0.05 and 2 mM. It was found that acidification of the surrounding medium takes place immediately after glucose addition and follows Michaelis-Menten kinetic behavior as a function of the glucose concentration. In future, the presented setup can, therefore, be used to study substrate specificities on the enzymatic level and may as well be used to perform investigations of more complex metabolic responses. Conclusions and perspectives highlighting this system are discussed.},
  language  = {en}
}
@article{KurowskiSchultzeLuethetal.2001,
  author    = {Kurowski, A. and Schultze, J.W. and L{\"u}th, H. and Sch{\"o}ning, Michael Josef},
  title     = {Micro- and nanopatterning of sensor chips by means of macroporous silicon},
  series = {Transducers '01 Eurosensors XV : digest of technical papers / the 11th International Conference on Solid-State Sensors and Actuators, June 10-14, 2001, Munich, Germany. Ernst Obermeier (Ed.)},
  journal   = {Transducers '01 Eurosensors XV : digest of technical papers / the 11th International Conference on Solid-State Sensors and Actuators, June 10-14, 2001, Munich, Germany. Ernst Obermeier (Ed.)},
  publisher = {Springer},
  address   = {Berlin [u.a.]},
  isbn      = {3-540-42150-5},
  pages     = {640 -- 643},
  year      = {2001},
  language  = {en}
}
@article{KurowskiSchultzeLuethetal.2002,
  author    = {Kurowski, A. and Schultze, J. and L{\"u}th, H. and Sch{\"o}ning, Michael Josef},
  title     = {Micro- and nanopatterning of sensor chips by means of macroporous silicon.},
  series = {Sensors and Actuators B. 83 (2002), H. 1-3},
  journal   = {Sensors and Actuators B. 83 (2002), H. 1-3},
  isbn      = {0925-4005},
  pages     = {123 -- 128},
  year      = {2002},
  language  = {en}
}
@article{SchoeningSchrothHummeletal.2001,
  author    = {Sch{\"o}ning, Michael Josef and Schroth, P. and Hummel, Hans E. and Weißbecker, B. and L{\"u}th, H. and Sch{\"u}tz, S.},
  title     = {Microcsaled living bioelectronic systems - Coupling beetles to silicon transducers},
  series = {Chemical and biological sensors and analytical methods : proceedings of the international symposium / Sensor, Physical Electrochemistry, and Organic and Biological Electrochemistry Divisions. Ed.: M. Butler},
  journal   = {Chemical and biological sensors and analytical methods : proceedings of the international symposium / Sensor, Physical Electrochemistry, and Organic and Biological Electrochemistry Divisions. Ed.: M. Butler},
  publisher = {Electrochemical Society},
  address   = {Pennington, NJ},
  isbn      = {1-56677-351-2},
  pages     = {165 -- 173},
  year      = {2001},
  language  = {en}
}
@article{SchmittWernerSchoening2002,
  author    = {Schmitt, G. and Werner, C. and Sch{\"o}ning, Michael Josef},
  title     = {Microelectrochemical efficiency evaluation of inhibitors for CO2 corrosion of carbon steel under high shear stress gradients},
  series = {Corrosion 2002. Conference Proceedings. NACExpo, 57th Annual Conference and Exhibition, Denver, US, Apr 7-11, 2002},
  journal   = {Corrosion 2002. Conference Proceedings. NACExpo, 57th Annual Conference and Exhibition, Denver, US, Apr 7-11, 2002},
  publisher = {NACE International},
  address   = {Houston, Texas},
  pages     = {1 -- 11},
  year      = {2002},
  language  = {en}
}
@article{SchoeningGlueckSchrothetal.1999,
  author    = {Sch{\"o}ning, Michael Josef and Gl{\"u}ck, O. and Schroth, P. and Sch{\"u}tz, S. (u.a.)},
  title     = {Microelectrodes, capacitors and BioFETs: Novel trends in silicon-based biochemical sensing},
  series = {Biocybernetics and Biomedical Engineering. 19 (1999), H. 1},
  journal   = {Biocybernetics and Biomedical Engineering. 19 (1999), H. 1},
  issn      = {0208-5216},
  pages     = {105 -- 126},
  year      = {1999},
  language  = {en}
}
@article{Schoening2001,
  author    = {Sch{\"o}ning, Michael Josef},
  title     = {Microelectronics contacts (bio-)chemistry - Semiconductor-based sensors},
  series = {Biologi Italiani. 8 (2001)},
  journal   = {Biologi Italiani. 8 (2001)},
  isbn      = {0392-2510},
  pages     = {5 -- 10},
  year      = {2001},
  language  = {en}
}
@article{SchoeningLueth2002,
  author    = {Sch{\"o}ning, Michael Josef and L{\"u}th, H.},
  title     = {Microfabricated semiconductor structures - Advances in (bio-)chemical sensing},
  series = {Coupling of biological and electronic systems : proceedings of the 2nd Caesarium, Bonn, November 1 - 3, 2000 / Karl-Heinz Hoffmann, ed.},
  journal   = {Coupling of biological and electronic systems : proceedings of the 2nd Caesarium, Bonn, November 1 - 3, 2000 / Karl-Heinz Hoffmann, ed.},
  publisher = {Springer},
  address   = {Berlin [u.a.]},
  isbn      = {3-540-43699-5},
  pages     = {79 -- 92},
  year      = {2002},
  language  = {en}
}
@article{AridaMohsenSchoening2009,
  author    = {Arida, Hassan and Mohsen, Q. and Sch{\"o}ning, Michael Josef},
  title     = {Microfabrication, characterization and analytical application of a new thin-film silver microsensor},
  series = {Electrochimica Acta. 54 (2009), H. 13},
  journal   = {Electrochimica Acta. 54 (2009), H. 13},
  isbn      = {0013-4686},
  pages     = {3543 -- 3547},
  year      = {2009},
  language  = {en}
}
@article{BaeckerRaueSchusseretal.2012,
  author    = {B{\"a}cker, Matthias and Raue, Markus and Schusser, Sebastian and Jeitner, C. and Breuer, L. and Wagner, P. and Poghossian, Arshak and F{\"o}rster, Arnold and Mang, Thomas and Sch{\"o}ning, Michael Josef},
  title     = {Microfluidic chip with integrated microvalves based on temperature- and pH-responsive hydrogel thin films},
  series = {Physica Status Solidi (a)},
  volume    = {209},
  journal   = {Physica Status Solidi (a)},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201100763},
  pages     = {839 -- 845},
  year      = {2012},
  abstract  = {Two types of microvalves based on temperature-responsive poly(N-isopropylacrylamide) (PNIPAAm) and pH-responsive poly(sodium acrylate) (PSA) hydrogel films have been developed and tested. The PNIPAAm and PSA hydrogel films were prepared by means of in situ photopolymerization directly inside the fluidic channel of a microfluidic chip fabricated by combining Si and SU-8 technologies. The swelling/shrinking properties and height changes of the PNIPAAm and PSA films inside the fluidic channel were studied at temperatures of deionized water from 14 to 36 °C and different pH values (pH 3-12) of Titrisol buffer, respectively. Additionally, in separate experiments, the lower critical solution temperature (LCST) of the PNIPAAm hydrogel was investigated by means of a differential scanning calorimetry (DSC) and a surface plasmon resonance (SPR) method. Mass-flow measurements have shown the feasibility of the prepared hydrogel films to work as an on-chip integrated temperature- or pH-responsive microvalve capable to switch the flow channel on/off.},
  language  = {en}
}
@article{WagnerMiyamotoShigiharaetal.2011,
  author    = {Wagner, Torsten and Miyamoto, Ko-ichiro and Shigihara, Noriko and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo},
  title     = {Microfluidic systems with free definable sensor spots by an integrated light-addressable potentiometric sensor},
  series = {Procedia Engineering. 25 (2011)},
  journal   = {Procedia Engineering. 25 (2011)},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {1877-7058},
  pages     = {791 -- 794},
  year      = {2011},
  language  = {en}
}
@article{LeinhosSchusserBaeckeretal.2014,
  author    = {Leinhos, Marcel and Schusser, Sebastian and B{\"a}cker, Matthias and Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {Micromachined multi-parameter sensor chip for the control of polymer-degradation medium},
  series = {Physica Status Solidi (A) : special issue on engineering and functional interfaces},
  volume    = {211},
  journal   = {Physica Status Solidi (A) : special issue on engineering and functional interfaces},
  number    = {6},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)},
  doi       = {10.1002/pssa.201330364},
  pages     = {1346 -- 1351},
  year      = {2014},
  abstract  = {It is well known that the degradation environment can strongly influence the biodegradability and kinetics of biodegradation processes of polymers. Therefore, besides the monitoring of the degradation process, it is also necessary to control the medium in which the degradation takes place. In this work, a micromachined multi-parameter sensor chip for the control of the polymer-degradation medium has been developed. The chip combines a capacitive field-effect pH sensor, a four-electrode electrolyte-conductivity sensor and a thin-film Pt-temperature sensor. The results of characterization of individual sensors are presented. In addition, the multi-parameter sensor chip together with an impedimetric polymer-degradation sensor was simultaneously characterized in degradation solutions with different pH and electrolyte conductivity. The obtained results demonstrate the feasibility of the multi-parameter sensor chip for the control of the polymer-degradation medium.},
  language  = {en}
}
@article{MoritzYoshinobuFingeretal.2004,
  author    = {Moritz, W. and Yoshinobu, T. and Finger, F. and Krause, S. and Xu, M. and Sch{\"o}ning, Michael Josef},
  title     = {Microscopy of impedance and surface ion concentrations},
  series = {Biomedizinische Technik. 49 (2004), H. 2},
  journal   = {Biomedizinische Technik. 49 (2004), H. 2},
  isbn      = {0932-4666},
  pages     = {1000 -- 1001},
  year      = {2004},
  language  = {en}
}
@article{PoghossianIngebrandtYeungetal.2004,
  author    = {Poghossian, Arshak and Ingebrandt, S. and Yeung, C.-K. and Offenh{\"a}usser, A. and Sch{\"o}ning, Michael Josef},
  title     = {Microsensors based on ion-sensitive field-effect transistors for biomedical applications},
  series = {Biomedizinische Technik. 49 (2004), H. 2},
  journal   = {Biomedizinische Technik. 49 (2004), H. 2},
  isbn      = {0932-4666},
  pages     = {1036 -- 1037},
  year      = {2004},
  language  = {en}
}
@article{SchoeningNaetherAugeretal.2005,
  author    = {Sch{\"o}ning, Michael Josef and N{\"a}ther, Niko and Auger, V. and Poghossian, Arshak and Koudelka-Hep, M.},
  title     = {Miniaturised flow-through cell with integrated capacitive EIS sensor fabricated at wafer level using Si and SU-8 technologies},
  series = {Sensors and Actuators B. 108 (2005), H. 1-2},
  journal   = {Sensors and Actuators B. 108 (2005), H. 1-2},
  isbn      = {0925-4005},
  pages     = {986 -- 992},
  year      = {2005},
  language  = {en}
}
@article{SimonisDawgulLuethetal.2005,
  author    = {Simonis, A. and Dawgul, M. and L{\"u}th, H. and Sch{\"o}ning, Michael Josef},
  title     = {Miniaturised reference electrodes for field-effect sensors compatible to silicon chip technology},
  series = {Electrochimica Acta. 51 (2005), H. 5},
  journal   = {Electrochimica Acta. 51 (2005), H. 5},
  isbn      = {0013-4686},
  doi       = {10.1016/j.electacta.2005.04.063},
  pages     = {930 -- 937},
  year      = {2005},
  language  = {en}
}
@article{SchoeningRonkelCrottetal.1997,
  author    = {Sch{\"o}ning, Michael Josef and Ronkel, F. and Crott, M. and Thust, M. (u.a.)},
  title     = {Miniaturization of potentiometric sensors using porous silicon microtechnology},
  series = {Electrochimica Acta. 42 (1997), H. 22},
  journal   = {Electrochimica Acta. 42 (1997), H. 22},
  isbn      = {0013-4686},
  pages     = {3185 -- 3193},
  year      = {1997},
  language  = {en}
}
@article{MiyamotoKanekoMatsuoetal.2010,
  author    = {Miyamoto, Ko-ichiro and Kaneko, Kazumi and Matsuo, Akira and Wagner, Torsten and Kanoh, Shin`ichiro and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo},
  title     = {Miniaturized chemical imaging sensor system using an OLED display panel},
  series = {Procedia Engineering. 5 (2010)},
  journal   = {Procedia Engineering. 5 (2010)},
  isbn      = {1877-7058},
  pages     = {516 -- 519},
  year      = {2010},
  language  = {en}
}
@article{MiyamotoKanekoMatsuoetal.2012,
  author    = {Miyamoto, Ko-ichiro and Kaneko, Kazumi and Matsuo, Akira and Wagner, Torsten and Kanoh, Shin{\´i}chiro and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo},
  title     = {Miniaturized chemical imaging sensor system using an OLED display panel},
  series = {Sensors and Actuators B: Chemical},
  volume    = {170},
  journal   = {Sensors and Actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2011.02.029},
  pages     = {82 -- 87},
  year      = {2012},
  abstract  = {The chemical imaging sensor is a semiconductor-based chemical sensor that can visualize the two-dimensional distribution of specific ions or molecules in the solution. In this study, we developed a miniaturized chemical imaging sensor system with an OLED display panel as a light source that scans the sensor plate. In the proposed configuration, the display panel is placed directly below the sensor plate and illuminates the back surface. The measured area defined by illumination can be arbitrarily customized to fit the size and the shape of the sample to be measured. The waveform of the generated photocurrent, the current-voltage characteristics and the pH sensitivity were investigated and pH imaging with this miniaturized system was demonstrated.},
  language  = {en}
}
@article{SchoeningNaetherAugeretal.2004,
  author    = {Sch{\"o}ning, Michael Josef and N{\"a}ther, Niko and Auger, V. and Poghossian, Arshak and Koudelka-Hep, M.},
  title     = {Miniaturized flow-through cell with integrated capacitive EIS sensors fabricated at wafer level using Si and Su-8 technologies},
  series = {Technical digest of the 10th International Meeting on Chemical Sensors, July 11 - 14, 2004, Tsukuba, Japan / Japan Association of Chemical Sensors},
  journal   = {Technical digest of the 10th International Meeting on Chemical Sensors, July 11 - 14, 2004, Tsukuba, Japan / Japan Association of Chemical Sensors},
  publisher = {Japan Association of Chemical Sensors},
  address   = {Fukuoka},
  pages     = {554 -- 555},
  year      = {2004},
  language  = {en}
}
@article{MolinnusIkenJohnenetal.2022,
  author    = {Molinnus, Denise and Iken, Heiko and Johnen, Anna Lynn and Richstein, Benjamin and Hellmich, Lena and Poghossian, Arshak and Knoch, Joachim and Sch{\"o}ning, Michael Josef},
  title     = {Miniaturized pH-Sensitive Field-Effect Capacitors with Ultrathin Ta₂O₅ Films Prepared by Atomic Layer Deposition},
  series = {physica status solidi (a) applications and materials science},
  volume    = {219},
  journal   = {physica status solidi (a) applications and materials science},
  number    = {8},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.202100660},
  pages     = {7 Seiten},
  year      = {2022},
  abstract  = {Miniaturized electrolyte-insulator-semiconductor capacitors (EISCAPs) with ultrathin gate insulators have been studied in terms of their pH-sensitive sensor characteristics: three different EISCAP systems consisting of Al-p-Si-Ta2O5(5 nm), Al-p-Si-Si3N4(1 or 2 nm)-Ta2O5 (5 nm), and Al-p-Si-SiO2(3.6 nm)-Ta2O5(5 nm) layer structures are characterized in buffer solution with different pH values by means of capacitance-voltage and constant capacitance method. The SiO2 and Si3N4 gate insulators are deposited by rapid thermal oxidation and rapid thermal nitridation, respectively, whereas the Ta2O5 film is prepared by atomic layer deposition. All EISCAP systems have a clear pH response, favoring the stacked gate insulators SiO2-Ta2O5 when considering the overall sensor characteristics, while the Si3N4(1 nm)-Ta2O5 stack delivers the largest accumulation capacitance (due to the lower equivalent oxide thickness) and a higher steepness in the slope of the capacitance-voltage curve among the studied stacked gate insulator systems.},
  language  = {en}
}
@article{SchoeningBussLuethetal.1999,
  author    = {Sch{\"o}ning, Michael Josef and Buß, G. and L{\"u}th, H. and Schultze, J.W.},
  title     = {Modifications and characterization of a silicon-based microelectrode array},
  series = {Electrochimica Acta. 44 (1999), H. 21-22},
  journal   = {Electrochimica Acta. 44 (1999), H. 21-22},
  isbn      = {0013-4686},
  pages     = {3899 -- 3910},
  year      = {1999},
  language  = {en}
}
@article{GasparyanVitusevichOffenhaeusseretal.2011,
  author    = {Gasparyan, F.V. and Vitusevich, S.A. and Offenh{\"a}usser, A. and Sch{\"o}ning, Michael Josef},
  title     = {Modified charge fluctuation noise model for electrolyte-insulator-semiconductor devices},
  series = {Modern Physics Letters B (MPLB). 25 (2011), H. 11},
  journal   = {Modern Physics Letters B (MPLB). 25 (2011), H. 11},
  publisher = {World Scientific Publ.},
  address   = {Singapur},
  isbn      = {0217-9849},
  pages     = {831 -- 840},
  year      = {2011},
  language  = {en}
}
@article{BohrnStuetzFuchsetal.2012,
  author    = {Bohrn, U. and St{\"u}tz, E. and Fuchs, K. and Fleischer, M. and Sch{\"o}ning, Michael Josef and Wagner, P.},
  title     = {Monitoring of irritant gas using a whole-cell-based sensor system},
  series = {Sensors and Actuators B: Chemical},
  volume    = {175},
  journal   = {Sensors and Actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2012.05.088},
  pages     = {208 -- 217},
  year      = {2012},
  abstract  = {Cell-based sensors for the detection of gases have long been underrepresented, due to the cellular requirement of being cultured in a liquid environment. In this work we established a cell-based gas biosensor for the detection of toxic substances in air, by adapting a commercial sensor chip (Bionas®), previously used for the measurement of pollutants in liquids. Cells of the respiratory tract (A549, RPMI 2650, V79), which survive at a gas phase in a natural context, are used as biological receptors. The physiological cell parameters acidification, respiration and morphology are continuously monitored in parallel. Ammonia was used as a highly water-soluble model gas to test the feasibility of the sensor system. Infrared measurements confirmed the sufficiency of the medium draining method. This sensor system provides a basis for many sensor applications such as environmental monitoring, building technology and public security.},
  language  = {en}
}
@article{SchusserKrischerBaeckeretal.2015,
  author    = {Schusser, Sebastian and Krischer, Maximillian and B{\"a}cker, Matthias and Poghossian, Arshak and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Monitoring of the Enzymatically Catalyzed Degradation of Biodegradable Polymers by Means of Capacitive Field-Effect Sensors},
  series = {Analytical Chemistry},
  volume    = {87},
  journal   = {Analytical Chemistry},
  number    = {13},
  publisher = {ACS Publications},
  address   = {Washington, DC},
  issn      = {1520-6882},
  doi       = {10.1021/acs.analchem.5b00617},
  pages     = {6607 -- 6613},
  year      = {2015},
  abstract  = {Designing novel or optimizing existing biodegradable polymers for biomedical applications requires numerous tests on the effect of substances on the degradation process. In the present work, polymer-modified electrolyte-insulator-semiconductor (PMEIS) sensors have been applied for monitoring an enzymatically catalyzed degradation of polymers for the first time. The thin films of biodegradable polymer poly(d,l-lactic acid) and enzyme lipase were used as a model system. During degradation, the sensors were read-out by means of impedance spectroscopy. In order to interpret the data obtained from impedance measurements, an electrical equivalent circuit model was developed. In addition, morphological investigations of the polymer surface have been performed by means of in situ atomic force microscopy. The sensor signal change, which reflects the progress of degradation, indicates an accelerated degradation in the presence of the enzyme compared to hydrolysis in neutral pH buffer media. The degradation rate increases with increasing enzyme concentration. The obtained results demonstrate the potential of PMEIS sensors as a very promising tool for in situ and real-time monitoring of degradation of polymers.},
  language  = {en}
}
@article{KirchnerOberlaenderSucoetal.2013,
  author    = {Kirchner, Patrick and Oberl{\"a}nder, Jan and Suco, Henri-Pierre and Rysstad, Gunnar and Sch{\"o}ning, Michael Josef},
  title     = {Monitoring the microbicidal effectiveness of gaseous hydrogen peroxide in sterilisation processes by means of a calorimetric gas sensor},
  series = {Food control},
  volume    = {31},
  journal   = {Food control},
  number    = {2},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0956-7135},
  doi       = {10.1016/j.foodcont.2012.11.048},
  pages     = {530 -- 538},
  year      = {2013},
  abstract  = {In the present work, a novel method for monitoring sterilisation processes with gaseous H2O2 in combination with heat activation by means of a specially designed calorimetric gas sensor was evaluated. Therefore, the sterilisation process was extensively studied by using test specimens inoculated with Bacillus atrophaeus spores in order to identify the most influencing process factors on its microbicidal effectiveness. Besides the contact time of the test specimens with gaseous H2O2 varied between 0.2 and 0.5 s, the present H2O2 concentration in a range from 0 to 8\% v/v (volume percent) had a strong influence on the microbicidal effectiveness, whereas the change of the vaporiser temperature, gas flow and humidity were almost negligible. Furthermore, a calorimetric H2O2 gas sensor was characterised in the sterilisation process with gaseous H2O2 in a wide range of parameter settings, wherein the measurement signal has shown a linear response against the H2O2 concentration with a sensitivity of 4.75 °C/(\% v/v). In a final step, a correlation model by matching the measurement signal of the gas sensor with the microbial inactivation kinetics was established that demonstrates its suitability as an efficient method for validating the microbicidal effectiveness of sterilisation processes with gaseous H2O2.},
  language  = {en}
}
@article{YoshinobuErmelenkoMourzinaetal.2003,
  author    = {Yoshinobu, T. and Ermelenko, Y. and Mourzina, Y. and Sch{\"o}ning, Michael Josef and Iwasaki, H. and Vlasov, Y.},
  title     = {Multi-component analysis based on the light-addressable potentiometric sensor (LAPS)},
  series = {Proceedings : 11th international conference Sensor 2003; 13 - 15 May 2003, Exhibition Centre Nuremberg, Germany},
  journal   = {Proceedings : 11th international conference Sensor 2003; 13 - 15 May 2003, Exhibition Centre Nuremberg, Germany},
  publisher = {AMA Service},
  address   = {Wunstorf},
  pages     = {141 -- 144},
  year      = {2003},
  language  = {en}
}
@article{PoghossianSchultzeSchoening2003,
  author    = {Poghossian, Arshak and Schultze, J. W. and Sch{\"o}ning, Michael Josef},
  title     = {Multi-parameter detection of (bio-)chemical and physical quantities using an identical transducer principle},
  series = {Sensors and Actuators B. 91 (2003), H. 1-3},
  journal   = {Sensors and Actuators B. 91 (2003), H. 1-3},
  isbn      = {0925-4005},
  pages     = {83 -- 91},
  year      = {2003},
  language  = {en}
}
@article{HuckPoghossianBaeckeretal.2015,
  author    = {Huck, Christina and Poghossian, Arshak and B{\"a}cker, Matthias and Reisert, Steffen and Kramer, Friederike and Begoyan, Vardges K. and Buniatyan, Vahe V. and Sch{\"o}ning, Michael Josef},
  title     = {Multi-parameter sensing using high-k oxide of barium strontium titanate},
  series = {Physica status solidi (a)},
  volume    = {212},
  journal   = {Physica status solidi (a)},
  number    = {6},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201431911},
  pages     = {1259},
  year      = {2015},
  abstract  = {High-k perovskite oxide of barium strontium titanate (BST) represents a very attractive multi-functional transducer material for the development of (bio-)chemical sensors. In this work, a Si-based sensor chip containing Pt interdigitated electrodes covered with a thin BST layer (485 nm) has been developed for multi-parameter chemical sensing. The chip has been applied for the contactless measurement of the electrolyte conductivity, the detection of adsorbed charged macromolecules (positively charged polyelectrolytes of polyethylenimine) and the concentration of hydrogen peroxide (H2O2) vapor. The experimental results of functional testing of individual sensors are presented. The mechanism of the BST sensitivity to charged polyelectrolytes and H2O2 vapor has been proposed and discussed.},
  language  = {en}
}
@article{ReisertSchneiderGeissleretal.2013,
  author    = {Reisert, Steffen and Schneider, Benno and Geissler, Hanno and Gompel, Matthias van and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Multi-sensor chip for the investigation of different types of metal oxides for the detection of H2O2 in the ppm range},
  series = {physica status solidi (a)},
  volume    = {210},
  journal   = {physica status solidi (a)},
  number    = {5},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1862-6319},
  pages     = {898 -- 904},
  year      = {2013},
  abstract  = {In this work, a multi-sensor chip for the investigation of the sensing properties of different types of metal oxides towards hydrogen peroxide in the ppm range is presented. The fabrication process and physical characterization of the multi-sensor chip are described. Pure SnO2 and WO3 as well as Pd- and Pt-doped SnO2 films are characterized in terms of their sensitivity to H2O2. The sensing films have been prepared by drop-coating of water-dispensed nano-powders. A physical characterization, including scanning electron microscopy and X-ray diffraction analysis of the deposited metal-oxide films, was done. From the measurements in hydrogen peroxide atmosphere, it could be shown, that all of the tested metal oxide films are suitable for the detection of H2O2 in the ppm range. The highest sensitivity and reproducibility was achieved using Pt-doped SnO2. Calibration plot of a SnO2, WO3, Pt-, and Pd-doped SnO2 gas sensor for H2O2 concentrations in the ppm range.},
  language  = {en}
}
@article{MiyamotoWagnerSchoeningetal.2011,
  author    = {Miyamoto, K. and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, T.},
  title     = {Multi-well structure for cell culture on the chemical imaging sensor},
  publisher = {IEEE},
  address   = {New York},
  pages     = {2130 -- 2132},
  year      = {2011},
  language  = {en}
}
@article{SchubertSchoeningMourzinaetal.2001,
  author    = {Schubert, J. and Sch{\"o}ning, Michael Josef and Mourzina, Y. G. and Legin, A. V. and Vlasov, Y. G. and Zander, W. and L{\"u}th, H.},
  title     = {Multicomponent thin films for electrochemical sensor applications prepared by pulsed laser deposition},
  series = {Sensors and Actuators B. 76 (2001), H. 1-3},
  journal   = {Sensors and Actuators B. 76 (2001), H. 1-3},
  isbn      = {0925-4005},
  pages     = {327 -- 330},
  year      = {2001},
  language  = {en}
}
@article{HuckPoghossianKerroumietal.2014,
  author    = {Huck, Christina and Poghossian, Arshak and Kerroumi, Iman and Schusser, Sebastian and B{\"a}cker, Matthias and Zander, Willi and Schubert, J{\"u}rgen and Buniatyan, Vahe V. and Martirosyan, Norayr W. and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Multiparameter sensor chip with Barium Strontium Titanate as multipurpose material},
  series = {Electroanalysis},
  volume    = {26},
  journal   = {Electroanalysis},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-4109 (E-Journal); 1040-0397 (Print)},
  doi       = {10.1002/elan.201400076},
  pages     = {980 -- 987},
  year      = {2014},
  abstract  = {It is well known that biochemical and biotechnological processes are strongly dependent and affected by a variety of physico-chemical parameters such as pH value, temperature, pressure and electrolyte conductivity. Therefore, these quantities have to be monitored or controlled in order to guarantee a stable process operation, optimization and high yield. In this work, a sensor chip for the multiparameter detection of three physico-chemical parameters such as electrolyte conductivity, pH and temperature is realized using barium strontium titanate (BST) as multipurpose material. The chip integrates a capacitively coupled four-electrode electrolyte-conductivity sensor, a capacitive field-effect pH sensor and a thin-film Pt-temperature sensor. Due to the multifunctional properties of BST, it is utilized as final outermost coating layer of the processed sensor chip and serves as passivation and protection layer as well as pH-sensitive transducer material at the same time. The results of testing of the individual sensors of the developed multiparameter sensor chip are presented. In addition, a quasi-simultaneous multiparameter characterization of the sensor chip in buffer solutions with different pH value and electrolyte conductivity is performed. To study the sensor behavior and the suitability of BST as multifunctional material under harsh environmental conditions, the sensor chip was exemplarily tested in a biogas digestate.},
  language  = {en}
}
@article{ReisertGeisslerWeileretal.2015,
  author    = {Reisert, Steffen and Geissler, H. and Weiler, C. and Wagner, P. and Sch{\"o}ning, Michael Josef},
  title     = {Multiple sensor-type system for monitoring the microbicidal effectiveness of aseptic sterilisation processes},
  series = {Food control},
  volume    = {47},
  journal   = {Food control},
  issn      = {1873-7129 (E-Journal); 0956-7135 (Print)},
  doi       = {10.1016/j.foodcont.2014.07.063},
  pages     = {615 -- 622},
  year      = {2015},
  abstract  = {The present work describes a novel multiple sensor-type system for the real-time analysis of aseptic sterilisation processes employing gaseous hydrogen peroxide (H2O2) as a sterilant. The inactivation kinetics of Bacillus atrophaeus by gaseous H2O2 have been investigated by means of a methodical calibration experiment, taking into account the process variables H2O2 concentration, humidity and gas temperature. It has been found that the microbicidal effectiveness at H2O2 concentrations above 2\% v/v is largely determined by the concentration itself, while at lower H2O2 concentrations, the gas temperature and humidity play a leading role. Furthermore, the responses of different types of gas sensors towards the influencing factors of the sterilisation process have been analysed within the same experiment. Based on a correlation established between the inactivation kinetics and the sensor responses, a calorimetric H2O2 sensor and a metal-oxide semiconductor (MOX) sensor have been identified as possible candidates for monitoring the microbicidal effectiveness of aseptic sterilisation processes employing gaseous H2O2. Therefore, two linear models that describe the relationship between sensor response and microbicidal effectiveness have been proposed.},
  language  = {en}
}