@article{WeldenSeverinsPoghossianetal.2022,
  author    = {Welden, Melanie and Severins, Robin and Poghossian, Arshak and Wege, Christina and Bongaerts, Johannes and Siegert, Petra and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Detection of acetoin and diacetyl by a tobacco mosaic virus-assisted field-effect biosensor},
  series = {Chemosensors},
  volume    = {10},
  journal   = {Chemosensors},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2227-9040},
  doi       = {10.3390/chemosensors10060218},
  pages     = {Artikel 218},
  year      = {2022},
  abstract  = {Acetoin and diacetyl have a major impact on the flavor of alcoholic beverages such as wine or beer. Therefore, their measurement is important during the fermentation process. Until now, gas chromatographic techniques have typically been applied; however, these require expensive laboratory equipment and trained staff, and do not allow for online monitoring. In this work, a capacitive electrolyte-insulator-semiconductor sensor modified with tobacco mosaic virus (TMV) particles as enzyme nanocarriers for the detection of acetoin and diacetyl is presented. The enzyme acetoin reductase from Alkalihalobacillus clausii DSM 8716ᵀ is immobilized via biotin-streptavidin affinity, binding to the surface of the TMV particles. The TMV-assisted biosensor is electrochemically characterized by means of leakage-current, capacitance-voltage, and constant capacitance measurements. In this paper, the novel biosensor is studied regarding its sensitivity and long-term stability in buffer solution. Moreover, the TMV-assisted capacitive field-effect sensor is applied for the detection of diacetyl for the first time. The measurement of acetoin and diacetyl with the same sensor setup is demonstrated. Finally, the successive detection of acetoin and diacetyl in buffer and in diluted beer is studied by tuning the sensitivity of the biosensor using the pH value of the measurement solution.},
  language  = {en}
}
@article{OjovanSteinmetz2022,
  author    = {Ojovan, Michael I. and Steinmetz, Hans-J{\"u}rgen},
  title     = {Approaches to Disposal of Nuclear Waste},
  series = {Energies},
  volume    = {15},
  journal   = {Energies},
  number    = {20},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1996-1073},
  doi       = {10.3390/en15207804},
  pages     = {Artikel 7804},
  year      = {2022},
  abstract  = {We present a concise mini overview on the approaches to the disposal of nuclear waste currently used or deployed. The disposal of nuclear waste is the end point of nuclear waste management (NWM) activities and is the emplacement of waste in an appropriate facility without the intention to retrieve it. The IAEA has developed an internationally accepted classification scheme based on the end points of NWM, which is used as guidance. Retention times needed for safe isolation of waste radionuclides are estimated based on the radiotoxicity of nuclear waste. Disposal facilities usually rely on a multi-barrier defence system to isolate the waste from the biosphere, which comprises the natural geological barrier and the engineered barrier system. Disposal facilities could be of a trench type, vaults, tunnels, shafts, boreholes, or mined repositories. A graded approach relates the depth of the disposal facilities' location with the level of hazard. Disposal practices demonstrate the reliability of nuclear waste disposal with minimal expected impacts on the environment and humans.},
  language  = {en}
}
@article{ZhantlessovaSavitskayaKistaubayevaetal.2022,
  author    = {Zhantlessova, Sirina and Savitskaya, Irina and Kistaubayeva, Aida and Ignatova, Ludmila and Talipova, Aizhan and Pogrebnjak, Alexander and Digel, Ilya},
  title     = {Advanced "Green" prebiotic composite of bacterial cellulose/pullulan based on synthetic biology-powered microbial coculture strategy},
  series = {Polymers},
  volume    = {14},
  journal   = {Polymers},
  number    = {15},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2073-4360},
  doi       = {10.3390/polym14153224},
  pages     = {Artikel 3224},
  year      = {2022},
  abstract  = {Bacterial cellulose (BC) is a biopolymer produced by different microorganisms, but in biotechnological practice, Komagataeibacter xylinus is used. The micro- and nanofibrillar structure of BC, which forms many different-sized pores, creates prerequisites for the introduction of other polymers into it, including those synthesized by other microorganisms. The study aims to develop a cocultivation system of BC and prebiotic producers to obtain BC-based composite material with prebiotic activity. In this study, pullulan (PUL) was found to stimulate the growth of the probiotic strain Lactobacillus rhamnosus GG better than the other microbial polysaccharides gellan and xanthan. BC/PUL biocomposite with prebiotic properties was obtained by cocultivation of Komagataeibacter xylinus and Aureobasidium pullulans, BC and PUL producers respectively, on molasses medium. The inclusion of PUL in BC is proved gravimetrically by scanning electron microscopy and by Fourier transformed infrared spectroscopy. Cocultivation demonstrated a composite effect on the aggregation and binding of BC fibers, which led to a significant improvement in mechanical properties. The developed approach for "grafting" of prebiotic activity on BC allows preparation of environmentally friendly composites of better quality.},
  language  = {en}
}
@article{WeldenPoghossianVahidpouretal.2022,
  author    = {Welden, Melanie and Poghossian, Arshak and Vahidpour, Farnoosh and Wendlandt, Tim and Keusgen, Michael and Wege, Christina and Sch{\"o}ning, Michael Josef},
  title     = {Towards multi-analyte detection with field-effect capacitors modified with tobacco mosaic virus bioparticles as enzyme nanocarriers},
  series = {Biosensors},
  volume    = {12},
  journal   = {Biosensors},
  number    = {1},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2079-6374},
  doi       = {10.3390/bios12010043},
  pages     = {Artikel 43},
  year      = {2022},
  abstract  = {Utilizing an appropriate enzyme immobilization strategy is crucial for designing enzyme-based biosensors. Plant virus-like particles represent ideal nanoscaffolds for an extremely dense and precise immobilization of enzymes, due to their regular shape, high surface-to-volume ratio and high density of surface binding sites. In the present work, tobacco mosaic virus (TMV) particles were applied for the co-immobilization of penicillinase and urease onto the gate surface of a field-effect electrolyte-insulator-semiconductor capacitor (EISCAP) with a p-Si-SiO₂-Ta₂O₅ layer structure for the sequential detection of penicillin and urea. The TMV-assisted bi-enzyme EISCAP biosensor exhibited a high urea and penicillin sensitivity of 54 and 85 mV/dec, respectively, in the concentration range of 0.1-3 mM. For comparison, the characteristics of single-enzyme EISCAP biosensors modified with TMV particles immobilized with either penicillinase or urease were also investigated. The surface morphology of the TMV-modified Ta₂O₅-gate was analyzed by scanning electron microscopy. Additionally, the bi-enzyme EISCAP was applied to mimic an XOR (Exclusive OR) enzyme logic gate.},
  language  = {en}
}
@article{DitzhausGaigall2022,
  author    = {Ditzhaus, Marc and Gaigall, Daniel},
  title     = {Testing marginal homogeneity in Hilbert spaces with applications to stock market returns},
  series = {Test},
  volume    = {2022},
  journal   = {Test},
  number    = {31},
  publisher = {Springer},
  issn      = {1863-8260},
  doi       = {10.1007/s11749-022-00802-5},
  pages     = {749 -- 770},
  year      = {2022},
  abstract  = {This paper considers a paired data framework and discusses the question of marginal homogeneity of bivariate high-dimensional or functional data. The related testing problem can be endowed into a more general setting for paired random variables taking values in a general Hilbert space. To address this problem, a Cram{\´e}r-von-Mises type test statistic is applied and a bootstrap procedure is suggested to obtain critical values and finally a consistent test. The desired properties of a bootstrap test can be derived that are asymptotic exactness under the null hypothesis and consistency under alternatives. Simulations show the quality of the test in the finite sample case. A possible application is the comparison of two possibly dependent stock market returns based on functional data. The approach is demonstrated based on historical data for different stock market indices.},
  language  = {en}
}
@article{GaigallGerstenbergTrinh2022,
  author    = {Gaigall, Daniel and Gerstenberg, Julian and Trinh, Thi Thu Ha},
  title     = {Empirical process of concomitants for partly categorial data and applications in statistics},
  series = {Bernoulli},
  volume    = {28},
  journal   = {Bernoulli},
  number    = {2},
  publisher = {International Statistical Institute},
  address   = {Den Haag, NL},
  issn      = {1573-9759},
  doi       = {10.3150/21-BEJ1367},
  pages     = {803 -- 829},
  year      = {2022},
  abstract  = {On the basis of independent and identically distributed bivariate random vectors, where the components are categorial and continuous variables, respectively, the related concomitants, also called induced order statistic, are considered. The main theoretical result is a functional central limit theorem for the empirical process of the concomitants in a triangular array setting. A natural application is hypothesis testing. An independence test and a two-sample test are investigated in detail. The fairly general setting enables limit results under local alternatives and bootstrap samples. For the comparison with existing tests from the literature simulation studies are conducted. The empirical results obtained confirm the theoretical findings.},
  language  = {en}
}
@article{Gaigall2021,
  author    = {Gaigall, Daniel},
  title     = {Test for Changes in the Modeled Solvency Capital Requirement of an Internal Risk Model},
  series = {ASTIN Bulletin},
  volume    = {51},
  journal   = {ASTIN Bulletin},
  number    = {3},
  publisher = {Cambridge Univ. Press},
  address   = {Cambridge},
  issn      = {1783-1350},
  doi       = {10.1017/asb.2021.20},
  pages     = {813 -- 837},
  year      = {2021},
  abstract  = {In the context of the Solvency II directive, the operation of an internal risk model is a possible way for risk assessment and for the determination of the solvency capital requirement of an insurance company in the European Union. A Monte Carlo procedure is customary to generate a model output. To be compliant with the directive, validation of the internal risk model is conducted on the basis of the model output. For this purpose, we suggest a new test for checking whether there is a significant change in the modeled solvency capital requirement. Asymptotic properties of the test statistic are investigated and a bootstrap approximation is justified. A simulation study investigates the performance of the test in the finite sample case and confirms the theoretical results. The internal risk model and the application of the test is illustrated in a simplified example. The method has more general usage for inference of a broad class of law-invariant and coherent risk measures on the basis of a paired sample.},
  language  = {en}
}
@article{Gaigall2020,
  author    = {Gaigall, Daniel},
  title     = {Hoeffding-Blum-Kiefer-Rosenblatt independence test statistic on partly not identically distributed data},
  series = {Communications in Statistics - Theory and Methods},
  volume    = {51},
  journal   = {Communications in Statistics - Theory and Methods},
  number    = {12},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {1532-415X},
  doi       = {10.1080/03610926.2020.1805767},
  pages     = {4006 -- 4028},
  year      = {2020},
  abstract  = {The established Hoeffding-Blum-Kiefer-Rosenblatt independence test statistic is investigated for partly not identically distributed data. Surprisingly, it turns out that the statistic has the well-known distribution-free limiting null distribution of the classical criterion under standard regularity conditions. An application is testing goodness-of-fit for the regression function in a non parametric random effects meta-regression model, where the consistency is obtained as well. Simulations investigate size and power of the approach for small and moderate sample sizes. A real data example based on clinical trials illustrates how the test can be used in applications.},
  language  = {en}
}
@article{MorandiButenwegBreisetal.2022,
  author    = {Morandi, Paolo and Butenweg, Christoph and Breis, Khaled and Beyer, Katrin and Magenes, Guido},
  title     = {Latest findings on the behaviour factor q for the seismic design of URM buildings},
  series = {Bulletin of Earthquake Engineering},
  volume    = {20},
  journal   = {Bulletin of Earthquake Engineering},
  number    = {11},
  editor    = {Ansal, Atilla},
  publisher = {Springer Nature},
  address   = {Cham},
  issn      = {1573-1456},
  doi       = {10.1007/s10518-022-01419-7},
  pages     = {5797 -- 5848},
  year      = {2022},
  abstract  = {Recent earthquakes as the 2012 Emilia earthquake sequence showed that recently built unreinforced masonry (URM) buildings behaved much better than expected and sustained, despite the maximum PGA values ranged between 0.20-0.30 g, either minor damage or structural damage that is deemed repairable. Especially low-rise residential and commercial masonry buildings with a code-conforming seismic design and detailing behaved in general very well without substantial damages. The low damage grades of modern masonry buildings that was observed during this earthquake series highlighted again that codified design procedures based on linear analysis can be rather conservative. Although advances in simulation tools make nonlinear calculation methods more readily accessible to designers, linear analyses will still be the standard design method for years to come. The present paper aims to improve the linear seismic design method by providing a proper definition of the q-factor of URM buildings. These q-factors are derived for low-rise URM buildings with rigid diaphragms which represent recent construction practise in low to moderate seismic areas of Italy and Germany. The behaviour factor components for deformation and energy dissipation capacity and for overstrength due to the redistribution of forces are derived by means of pushover analyses. Furthermore, considerations on the behaviour factor component due to other sources of overstrength in masonry buildings are presented. As a result of the investigations, rationally based values of the behaviour factor q to be used in linear analyses in the range of 2.0-3.0 are proposed.},
  language  = {en}
}
@article{ButenwegMarinkovicPhlippetal.2022,
  author    = {Butenweg, Christoph and Marinkovic, Marko and Phlipp, Michel and Lins, Robin and Renaut, Philipp},
  title     = {Isolierung und BIM-basiertes Bauwerksmonitoring des neuen Geb{\"a}udekomplexes f{\"u}r das BioSense-Institut in Novi Sad, Serbien},
  series = {Bauingenieur},
  volume    = {97},
  journal   = {Bauingenieur},
  number    = {6},
  editor    = {Haghsheno, Shervin},
  publisher = {VDI Fachmedien},
  address   = {D{\"u}sseldorf},
  issn      = {1436-4867},
  doi       = {10.37544/0005-6650-2022-06-28},
  pages     = {S3 -- S5},
  year      = {2022},
  abstract  = {Im Norden von Serbien erfolgt in Novi Sad der Neubau eines modernen Forschungsgeb{\"a}udes f{\"u}r das BioSense-Institut mit finanzieller Unterst{\"u}tzung durch die Eu-rop{\"a}ische Union. Der Geb{\"a}udeteil mit Laboren wird zum Schutz und zur Sicherstellung des reibungslosen Betriebs der sensiblen und kapitalintensiven technischen Einbauten mit ei-ner Erdbebenisolierung mit integrierter K{\"o}rperschallisolation versehen. Zus{\"a}tzlich wird der entkoppelte Laborteil des For-schungsgeb{\"a}udes mit einem BIM-basierten Bauwerksmonito-ring versehen, um {\"A}nderungen des Geb{\"a}udezustands jederzeit abfragen und beurteilen zu k{\"o}nnen.},
  language  = {de}
}
@article{KubalskiButenwegElDeib2022,
  author    = {Kubalski, Thomas and Butenweg, Christoph and El-Deib, Khaled},
  title     = {Vereinfachte Ber{\"u}cksichtigung der Rahmentragwirkung in Mauerwerksgeb{\"a}uden},
  series = {Bautechnik},
  volume    = {99},
  journal   = {Bautechnik},
  number    = {12},
  editor    = {Jesse, Dirk},
  publisher = {Ernst \& Sohn},
  address   = {Berlin},
  issn      = {0932-8351},
  doi       = {10.1002/bate.202200081},
  pages     = {865 -- 928},
  year      = {2022},
  abstract  = {Aufgrund der gestiegenen Anforderungen durch h{\"o}here Ein-wirkungen aus Wind und Erdbeben ist eine Verbesserung und Optimierung der Berechnungs- und Bemessungsans{\"a}tze f{\"u}r Mauerwerksbauten erforderlich. Eine bessere Ausnutzung der Tragwerksreserven ist durch die Ber{\"u}cksichtigung der Rah-mentragwirkung mit einer Aktivierung der Deckenscheiben in den Rechenmodellen m{\"o}glich, die in der Praxis aufgrund der Komplexit{\"a}t der Wand-Decken-Interaktion bislang nicht aus-genutzt wird. Im vorliegenden Aufsatz wird ein vereinfachter Ansatz auf Grundlage der mitwirkenden Plattenbreite von Schubw{\"a}nden aus Mauerwerk vorgestellt, der die wesentli-chen Einfl ussfaktoren in parametrisierten Tabellen erfasst. Damit steht den Tragwerksplanern ein einfach anwendbares Werkzeug zur Verf{\"u}gung, um die Rahmentragwirkung in der Mauerwerksbemessung anzusetzen.},
  language  = {de}
}
@article{ŠakićMarinkovićButenwegetal.2023,
  author    = {Šakić, Bogdan and Marinković, Marko and Butenweg, Christoph and Klinkel, Sven},
  title     = {Influence of slab deflection on the out-of-plane capacity of unreinforced masonry partition walls},
  series = {Engineering Structures},
  volume    = {276},
  journal   = {Engineering Structures},
  editor    = {Yang, J.},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0141-0296},
  doi       = {10.1016/j.engstruct.2022.115342},
  year      = {2023},
  abstract  = {Severe damage of non-structural elements is noticed in previous earthquakes, causing high economic losses and posing a life threat for the people. Masonry partition walls are one of the most commonly used non-structural elements. Therefore, their behaviour under earthquake loading in out-of-plane (OOP) direction is investigated by several researches in the past years. However, none of the existing experimental campaigns or analytical approaches consider the influence of prior slab deflection on OOP response of partition walls. Moreover, none of the existing construction techniques for the connection of partition walls with surrounding reinforced concrete (RC) is investigated for the combined slab deflection and OOP loading. However, the inevitable time-dependent behaviour of RC slabs leads to high values of final slab deflections which can further influence boundary conditions of partition walls. Therefore, a comprehensive study on the influence of slab deflection on the OOP capacity of masonry partitions is conducted. In the first step, experimental tests are carried out. Results of experimental tests are further used for the calibration of the numerical model employed for a parametric study. Based on the results, behaviour under combined loading for different construction techniques is explained. The results show that slab deflection leads either to severe damage or to a high reduction of OOP capacity. Existing practical solutions do not account for these effects. In this contribution, recommendations to overcome the problems of combined slab deflection and OOP loading on masonry partition walls are given. Possible interaction of in-plane (IP) loading, with the combined slab deflection and OOP loading on partition walls, is not investigated in this study.},
  language  = {en}
}
@article{WeldenJablonskiWegeetal.2021,
  author    = {Welden, Rene and Jablonski, Melanie and Wege, Christina and Keusgen, Michael and Wagner, Patrick Hermann and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Light-Addressable Actuator-Sensor Platform for Monitoring and Manipulation of pH Gradients in Microfluidics: A Case Study with the Enzyme Penicillinase},
  series = {Biosensors},
  volume    = {11},
  journal   = {Biosensors},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2079-6374},
  doi       = {10.3390/bios11060171},
  pages     = {Artikel 171},
  year      = {2021},
  abstract  = {The feasibility of light-addressed detection and manipulation of pH gradients inside an electrochemical microfluidic cell was studied. Local pH changes, induced by a light-addressable electrode (LAE), were detected using a light-addressable potentiometric sensor (LAPS) with different measurement modes representing an actuator-sensor system. Biosensor functionality was examined depending on locally induced pH gradients with the help of the model enzyme penicillinase, which had been immobilized in the microfluidic channel. The surface morphology of the LAE and enzyme-functionalized LAPS was studied by scanning electron microscopy. Furthermore, the penicillin sensitivity of the LAPS inside the microfluidic channel was determined with regard to the analyte's pH influence on the enzymatic reaction rate. In a final experiment, the LAE-controlled pH inhibition of the enzyme activity was monitored by the LAPS.},
  language  = {en}
}
@article{SchoeningBronderWuetal.2017,
  author    = {Sch{\"o}ning, Michael Josef and Bronder, Thomas and Wu, Chunsheng and Scheja, Sabrina and Jessing, Max and Metzger-Boddien, Christoph and Keusgen, Michael and Poghossian, Arshak},
  title     = {Label-Free DNA Detection with Capacitive Field-Effect Devices—Challenges and Opportunities},
  series = {Proceedings},
  volume    = {1},
  journal   = {Proceedings},
  number    = {8},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2504-3900},
  doi       = {10.3390/proceedings1080719},
  pages     = {Artikel 719},
  year      = {2017},
  abstract  = {Field-effect EIS (electrolyte-insulator-semiconductor) sensors modified with a positively charged weak polyelectrolyte layer have been applied for the electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge. The EIS sensors are able to detect the existence of target DNA amplicons in PCR (polymerase chain reaction) samples and thus, can be used as tool for a quick verification of DNA amplification and the successful PCR process. Due to their miniaturized setup, compatibility with advanced micro- and nanotechnologies, and ability to detect biomolecules by their intrinsic molecular charge, those sensors can serve as possible platform for the development of label-free DNA chips. Possible application fields as well as challenges and limitations will be discussed.},
  language  = {en}
}
@article{Gaigall2020,
  author    = {Gaigall, Daniel},
  title     = {Testing marginal homogeneity of a continuous bivariate distribution with possibly incomplete paired data},
  series = {Metrika},
  volume    = {2020},
  journal   = {Metrika},
  number    = {83},
  publisher = {Springer},
  issn      = {1435-926X},
  doi       = {10.1007/s00184-019-00742-5},
  pages     = {437 -- 465},
  year      = {2020},
  abstract  = {We discuss the testing problem of homogeneity of the marginal distributions of a continuous bivariate distribution based on a paired sample with possibly missing components (missing completely at random). Applying the well-known two-sample Cr{\´a}mer-von-Mises distance to the remaining data, we determine the limiting null distribution of our test statistic in this situation. It is seen that a new resampling approach is appropriate for the approximation of the unknown null distribution. We prove that the resulting test asymptotically reaches the significance level and is consistent. Properties of the test under local alternatives are pointed out as well. Simulations investigate the quality of the approximation and the power of the new approach in the finite sample case. As an illustration we apply the test to real data sets.},
  language  = {en}
}
@article{Gaigall2020,
  author    = {Gaigall, Daniel},
  title     = {Rothman-Woodroofe symmetry test statistic revisited},
  series = {Computational Statistics \& Data Analysis},
  volume    = {2020},
  journal   = {Computational Statistics \& Data Analysis},
  number    = {142},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0167-9473},
  doi       = {10.1016/j.csda.2019.106837},
  pages     = {Artikel 106837},
  year      = {2020},
  abstract  = {The Rothman-Woodroofe symmetry test statistic is revisited on the basis of independent but not necessarily identically distributed random variables. The distribution-freeness if the underlying distributions are all symmetric and continuous is obtained. The results are applied for testing symmetry in a meta-analysis random effects model. The consistency of the procedure is discussed in this situation as well. A comparison with an alternative proposal from the literature is conducted via simulations. Real data are analyzed to demonstrate how the new approach works in practice.},
  language  = {en}
}
@article{BaringhausGaigall2019,
  author    = {Baringhaus, Ludwig and Gaigall, Daniel},
  title     = {On an asymptotic relative efficiency concept based on expected volumes of confidence regions},
  series = {Statistics - A Journal of Theoretical and Applied Statistic},
  volume    = {53},
  journal   = {Statistics - A Journal of Theoretical and Applied Statistic},
  number    = {6},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {1029-4910},
  doi       = {10.1080/02331888.2019.1683560},
  pages     = {1396 -- 1436},
  year      = {2019},
  abstract  = {The paper deals with an asymptotic relative efficiency concept for confidence regions of multidimensional parameters that is based on the expected volumes of the confidence regions. Under standard conditions the asymptotic relative efficiencies of confidence regions are seen to be certain powers of the ratio of the limits of the expected volumes. These limits are explicitly derived for confidence regions associated with certain plugin estimators, likelihood ratio tests and Wald tests. Under regularity conditions, the asymptotic relative efficiency of each of these procedures with respect to each one of its competitors is equal to 1. The results are applied to multivariate normal distributions and multinomial distributions in a fairly general setting.},
  language  = {en}
}
@article{Gaigall2019,
  author    = {Gaigall, Daniel},
  title     = {On a new approach to the multi-sample goodness-of-fit problem},
  series = {Communications in Statistics - Simulation and Computation},
  volume    = {53},
  journal   = {Communications in Statistics - Simulation and Computation},
  number    = {10},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {1532-4141},
  doi       = {10.1080/03610918.2019.1618472},
  pages     = {2971 -- 2989},
  year      = {2019},
  abstract  = {Suppose we have k samples X₁,₁,…,X₁,ₙ₁,…,Xₖ,₁,…,Xₖ,ₙₖ with different sample sizes ₙ₁,…,ₙₖ and unknown underlying distribution functions F₁,…,Fₖ as observations plus k families of distribution functions {G₁(⋅,ϑ);ϑ∈Θ},…,{Gₖ(⋅,ϑ);ϑ∈Θ}, each indexed by elements ϑ from the same parameter set Θ, we consider the new goodness-of-fit problem whether or not (F₁,…,Fₖ) belongs to the parametric family {(G₁(⋅,ϑ),…,Gₖ(⋅,ϑ));ϑ∈Θ}. New test statistics are presented and a parametric bootstrap procedure for the approximation of the unknown null distributions is discussed. Under regularity assumptions, it is proved that the approximation works asymptotically, and the limiting distributions of the test statistics in the null hypothesis case are determined. Simulation studies investigate the quality of the new approach for small and moderate sample sizes. Applications to real-data sets illustrate how the idea can be used for verifying model assumptions.},
  language  = {en}
}
@article{DitzhausGaigall2018,
  author    = {Ditzhaus, Marc and Gaigall, Daniel},
  title     = {A consistent goodness-of-fit test for huge dimensional and functional data},
  series = {Journal of Nonparametric Statistics},
  volume    = {30},
  journal   = {Journal of Nonparametric Statistics},
  number    = {4},
  publisher = {Taylor \& Francis},
  address   = {Abingdon},
  issn      = {1029-0311},
  doi       = {10.1080/10485252.2018.1486402},
  pages     = {834 -- 859},
  year      = {2018},
  abstract  = {A nonparametric goodness-of-fit test for random variables with values in a separable Hilbert space is investigated. To verify the null hypothesis that the data come from a specific distribution, an integral type test based on a Cram{\´e}r-von-Mises statistic is suggested. The convergence in distribution of the test statistic under the null hypothesis is proved and the test's consistency is concluded. Moreover, properties under local alternatives are discussed. Applications are given for data of huge but finite dimension and for functional data in infinite dimensional spaces. A general approach enables the treatment of incomplete data. In simulation studies the test competes with alternative proposals.},
  language  = {en}
}
@article{BaringhausGaigallThiele2018,
  author    = {Baringhaus, Ludwig and Gaigall, Daniel and Thiele, Jan Philipp},
  title     = {Statistical inference for L²-distances to uniformity},
  series = {Computational Statistics},
  volume    = {2018},
  journal   = {Computational Statistics},
  number    = {33},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1613-9658},
  doi       = {10.1007/s00180-018-0820-0},
  pages     = {1863 -- 1896},
  year      = {2018},
  abstract  = {The paper deals with the asymptotic behaviour of estimators, statistical tests and confidence intervals for L²-distances to uniformity based on the empirical distribution function, the integrated empirical distribution function and the integrated empirical survival function. Approximations of power functions, confidence intervals for the L²-distances and statistical neighbourhood-of-uniformity validation tests are obtained as main applications. The finite sample behaviour of the procedures is illustrated by a simulation study.},
  language  = {en}
}
@article{BaringhausGaigall2018,
  author    = {Baringhaus, Ludwig and Gaigall, Daniel},
  title     = {Efficiency comparison of the Wilcoxon tests in paired and independent survey samples},
  series = {Metrika},
  volume    = {2018},
  journal   = {Metrika},
  number    = {81},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1435-926X},
  doi       = {10.1007/s00184-018-0661-4},
  pages     = {891 -- 930},
  year      = {2018},
  abstract  = {The efficiency concepts of Bahadur and Pitman are used to compare the Wilcoxon tests in paired and independent survey samples. A comparison through the length of corresponding confidence intervals is also done. Simple conditions characterizing the dominance of a procedure are derived. Statistical tests for checking these conditions are suggested and discussed.},
  language  = {de}
}
@article{BaringhausGaigall2017,
  author    = {Baringhaus, Ludwig and Gaigall, Daniel},
  title     = {On Hotelling's T² test in a special paired sample case},
  series = {Communications in Statistics - Theory and Methods},
  volume    = {48},
  journal   = {Communications in Statistics - Theory and Methods},
  number    = {2},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {1532-415X},
  doi       = {10.1080/03610926.2017.1408828},
  pages     = {257 -- 267},
  year      = {2017},
  abstract  = {In a special paired sample case, Hotelling's T² test based on the differences of the paired random vectors is the likelihood ratio test for testing the hypothesis that the paired random vectors have the same mean; with respect to a special group of affine linear transformations it is the uniformly most powerful invariant test for the general alternative of a difference in mean. We present an elementary straightforward proof of this result. The likelihood ratio test for testing the hypothesis that the covariance structure is of the assumed special form is derived and discussed. Applications to real data are given.},
  language  = {en}
}
@article{BaringhausGaigall2017,
  author    = {Baringhaus, Ludwig and Gaigall, Daniel},
  title     = {Hotelling's T² tests in paired and independent survey samples: An efficiency comparison},
  series = {Journal of Multivariate Analysis},
  volume    = {2017},
  journal   = {Journal of Multivariate Analysis},
  number    = {154},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0047-259X},
  doi       = {10.1016/j.jmva.2016.11.004},
  pages     = {177 -- 198},
  year      = {2017},
  abstract  = {Hotelling's T² tests in paired and independent survey samples are compared using the traditional asymptotic efficiency concepts of Hodges-Lehmann, Bahadur and Pitman, as well as through criteria based on the volumes of corresponding confidence regions. Conditions characterizing the superiority of a procedure are given in terms of population canonical correlation type coefficients. Statistical tests for checking these conditions are developed. Test statistics based on the eigenvalues of a symmetrized sample cross-covariance matrix are suggested, as well as test statistics based on sample canonical correlation type coefficients.},
  language  = {en}
}
@article{DickhoffHorikawaFunke2021,
  author    = {Dickhoff, Jens and Horikawa, Atsushi and Funke, Harald},
  title     = {Hydrogen Combustion - new DLE Combustor Addresses NOx Emissions and Flashback},
  series = {Turbomachinery international : the global journal of energy equipment},
  volume    = {62},
  journal   = {Turbomachinery international : the global journal of energy equipment},
  number    = {4},
  publisher = {MJH Life Sciences},
  address   = {Cranbury},
  issn      = {2767-2328},
  pages     = {26 -- 27},
  year      = {2021},
  language  = {en}
}
@article{MarinkovićFloresCalvinistiButenweg2020,
  author    = {Marinković, Marko and Flores Calvinisti, Santiago and Butenweg, Christoph},
  title     = {Numerical analysis of reinforced concrete frame buildings with decoupled infill walls},
  series = {Building Materials and Structures},
  volume    = {63},
  journal   = {Building Materials and Structures},
  number    = {4},
  publisher = {Society for Materials and Structures Testing of Serbia},
  address   = {Belgrad},
  issn      = {2217-8139},
  doi       = {10.5937/GRMK2004013M},
  pages     = {13 -- 48},
  year      = {2020},
  abstract  = {Reinforced concrete (RC) buildings with masonry infill walls are widely used in many countries all over the world. Although infills are considered as non-structural elements, they significantly change dynamic characteristics of RC frame structures during earthquake excitation. Recently, significant effort was spent on studying decoupled infills, which are isolated from the surrounding frame usually by adding a gap between frame and infill. In this case, the frame deformation does not activate infill wall, thus infills are not influencing the behaviour of the frame. This paper presents the results of the investigation of the behaviour of RC frame buildings with the INODIS system that decouples masonry infills from the surrounding frame. Effect of masonry infill decoupling was investigated first on the one-bay onestorey frame. This was used as a base for parametric study on the frames with more bays and storeys, as well as on the building level. Change of stiffness and dynamic characteristics was analysed as well as response under earthquake loading. Comparison with the bare frame and traditionally infilled frame was performed. The results show that behaviour of the decoupled infilled frames is similar to the bare frame, whereas behaviour of frames with traditional infills is significantly different and demands complex numerical models. This means that if adequate decoupling is applied, design of},
  language  = {mul}
}
@article{GorzalkaSchmiedtSchorn2021,
  author    = {Gorzalka, Philip and Schmiedt, Jacob Estevam and Schorn, Christian},
  title     = {Automated Generation of an Energy Simulation Model for an Existing Building from UAV Imagery},
  series = {Buildings},
  volume    = {11},
  journal   = {Buildings},
  number    = {9},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2075-5309},
  doi       = {10.3390/buildings11090380},
  pages     = {15 Seiten},
  year      = {2021},
  abstract  = {An approach to automatically generate a dynamic energy simulation model in Modelica for a single existing building is presented. It aims at collecting data about the status quo in the preparation of energy retrofits with low effort and costs. The proposed method starts from a polygon model of the outer building envelope obtained from photogrammetrically generated point clouds. The open-source tools TEASER and AixLib are used for data enrichment and model generation. A case study was conducted on a single-family house. The resulting model can accurately reproduce the internal air temperatures during synthetical heating up and cooling down. Modelled and measured whole building heat transfer coefficients (HTC) agree within a 12\% range. A sensitivity analysis emphasises the importance of accurate window characterisations and justifies the use of a very simplified interior geometry. Uncertainties arising from the use of archetype U-values are estimated by comparing different typologies, with best- and worst-case estimates showing differences in pre-retrofit heat demand of about ±20\% to the average; however, as the assumptions made are permitted by some national standards, the method is already close to practical applicability and opens up a path to quickly estimate possible financial and energy savings after refurbishment.},
  language  = {en}
}
@article{ButenwegMarinkovićKubalskietal.2018,
  author    = {Butenweg, Christoph and Marinković, Marko and Kubalski, Thomas and Fehling, Ekkehard and Pfetzing, Thomas and Meyer, Udo},
  title     = {Auslegung von Stahlbetonrahmentragwerken mit Ausfachungen aus Ziegelmauerwerk (Teil 1)},
  series = {Ziegelindustrie international : ZI = Brick and tile industry international},
  journal   = {Ziegelindustrie international : ZI = Brick and tile industry international},
  number    = {4},
  editor    = {Voss, Michael},
  publisher = {Bauverlag BV GmbH},
  address   = {G{\"u}tersloh},
  issn      = {0341-0552},
  pages     = {30 -- 39},
  year      = {2018},
  abstract  = {Im Rahmen des europ{\"a}ischen Verbundprojekts INSYSME wurden von den deutschen Partnern die Systeme IMES und INODIS zur Verbesserung des seismischen Verhaltens von ausgefachten Stahlbetonrahmen entwickelt. Ziel beider Systeme ist es, Stahlbetonrahmen und Ausfachung zu entkoppeln, anstatt die Tragf{\"a}higkeit durch aufwendige und kostspielige zus{\"a}tzliche Bewehrungseinlagen zu erh{\"o}hen. Erste Ergebnisse des Systems IMES f{\"u}r Belastungen in und senkrecht zu der Wandebene werden vorgestellt.},
  language  = {de}
}
@article{ButenwegMarinkovićKubalskietal.2018,
  author    = {Butenweg, Christoph and Marinković, Marko and Kubalski, Thomas and Fehling, Ekkehard and Pfetzing, Thomas and Meyer, Udo},
  title     = {Auslegung von Stahlbetonrahmentragwerken mit Ausfachungen aus Ziegelmauerwerk (Teil 2)},
  series = {Ziegelindustrie international : ZI = Brick and tile industry international},
  journal   = {Ziegelindustrie international : ZI = Brick and tile industry international},
  number    = {6},
  editor    = {Voss, Michael},
  publisher = {Bauverlag BV GmbH},
  address   = {G{\"u}tersloh},
  issn      = {0341-0552},
  pages     = {24 -- 43},
  year      = {2018},
  abstract  = {Im Rahmen des europ{\"a}ischen Verbundprojekts INSYSME wurden von den deutschen Partnern die Systeme IMES und INODIS zur Verbesserung des seismischen Verhaltens von ausgefachten Stahlbetonrahmen entwickelt. Ziel beider Systeme ist es, Stahlbetonrahmen und Ausfachung zu entkoppeln, anstatt die Tragf{\"a}higkeit durch aufwendige und kostspielige zus{\"a}tzliche Bewehrungseinlagen zu erh{\"o}hen. Erste Ergebnisse des Systems IMES f{\"u}r Belastungen in und senkrecht zu der Wandebene werden vorgestellt.},
  language  = {de}
}
@article{Gaigall2023,
  author    = {Gaigall, Daniel},
  title     = {Allocating and forecasting changes in risk},
  series = {Journal of risk},
  volume    = {25},
  journal   = {Journal of risk},
  number    = {3},
  editor    = {AitSahlia, Farid},
  publisher = {Infopro Digital Risk},
  address   = {London},
  issn      = {1755-2842},
  doi       = {10.21314/JOR.2022.048},
  pages     = {1 -- 24},
  year      = {2023},
  abstract  = {We consider time-dependent portfolios and discuss the allocation of changes in the risk of a portfolio to changes in the portfolio's components. For this purpose we adopt established allocation principles. We also use our approach to obtain forecasts for changes in the risk of the portfolio's components. To put the approach into practice we present an implementation based on the output of a simulation. Allocation is illustrated with an example portfolio in the context of Solvency II. The quality of the forecasts is investigated with an empirical study.},
  language  = {en}
}
@article{Gaigall2023,
  author    = {Gaigall, Daniel},
  title     = {On the applicability of several tests to models with not identically distributed random effects},
  series = {Statistics : A Journal of Theoretical and Applied Statistics},
  volume    = {57},
  journal   = {Statistics : A Journal of Theoretical and Applied Statistics},
  publisher = {Taylor \& Francis},
  address   = {London},
  isbn      = {0323-3944},
  issn      = {1029-4910},
  doi       = {10.1080/02331888.2023.2193748},
  pages     = {14 Seiten},
  year      = {2023},
  abstract  = {We consider Kolmogorov-Smirnov and Cram{\´e}r-von-Mises type tests for testing central symmetry, exchangeability, and independence. In the standard case, the tests are intended for the application to independent and identically distributed data with unknown distribution. The tests are available for multivariate data and bootstrap procedures are suitable to obtain critical values. We discuss the applicability of the tests to random effects models, where the random effects are independent but not necessarily identically distributed and with possibly unknown distributions. Theoretical results show the adequacy of the tests in this situation. The quality of the tests in models with random effects is investigated by simulations. Empirical results obtained confirm the theoretical findings. A real data example illustrates the application.},
  language  = {en}
}
@article{Esch2010,
  author    = {Esch, Thomas},
  title     = {Trends in commercial vehicle powertrains},
  series = {ATZautotechnology},
  volume    = {2010},
  journal   = {ATZautotechnology},
  number    = {10},
  publisher = {Vieweg \& Sohn},
  address   = {Wiesbaden},
  issn      = {2192-886X},
  doi       = {10.1007/BF03247185},
  pages     = {26 -- 31},
  year      = {2010},
  abstract  = {Low emission zones and truck bans, the rising price of diesel and increases in road tolls: all of these factors are putting serious pressure on the transport industry. Commercial vehicle manufacturers and their suppliers are in the process of identifying new solutions to these challenges as part of their efforts to meet the EEV (enhanced environmentally friendly vehicle) limits, which are currently the most robust European exhaust and emissions standards for trucks and buses.},
  language  = {en}
}
@article{ElsenHartungHornetal.2001,
  author    = {Elsen, Ingo and Hartung, Frank and Horn, Uwe and Kampmann, Markus and Peters, Liliane},
  title     = {Streaming technology in 3G mobile communication systems},
  series = {Computer : innovative technology for computer professionals},
  volume    = {34},
  journal   = {Computer : innovative technology for computer professionals},
  number    = {9 Seiten},
  editor    = {Voas, Jeffrey},
  publisher = {IEEE},
  address   = {New York},
  issn      = {0018-9162},
  pages     = {46 -- 52},
  year      = {2001},
  abstract  = {Third-generation mobile communication systems will combine standardized streaming with a range of unique services to provide high-quality Internet content that meets the specific needs of the rapidly growing mobile market.},
  language  = {en}
}
@article{FunkeEschRoosen2022,
  author    = {Funke, Harald and Esch, Thomas and Roosen, Petra},
  title     = {Antriebssystemanpassungen zur Verwendung von LPG als Flugkraftstoff},
  series = {Motortechnische Zeitschrift (MTZ)},
  volume    = {2022},
  journal   = {Motortechnische Zeitschrift (MTZ)},
  number    = {83},
  publisher = {Springer Nature},
  address   = {Basel},
  doi       = {10.1007/s35146-021-0778-2},
  pages     = {58 -- 62},
  year      = {2022},
  abstract  = {Auch in der allgemeinen Luftfahrt w{\"a}re es w{\"u}nschenswert, die bereits vorhandenen Verbrennungsmotoren mit weniger CO₂-tr{\"a}chtigen Kraftstoffen als dem heute weit verbreiteten Avgas 100LL betreiben zu k{\"o}nnen. Es ist anzunehmen, dass im Vergleich die unter Normalbedingungen gasf{\"o}rmigen Kraftstoffe CNG, LPG oder LNG deutlich weniger Emissionen produzieren. Erforderliche Antriebssystemanpassungen wurden im Rahmen eines Forschungsprojekts an der FH Aachen untersucht.},
  language  = {de}
}
@article{FunkeEschRoosen2022,
  author    = {Funke, Harald and Esch, Thomas and Roosen, Petra},
  title     = {Powertrain Adaptions for LPG Usage in General Aviation},
  series = {MTZ worldwide},
  volume    = {2022},
  journal   = {MTZ worldwide},
  number    = {83},
  publisher = {Springer Nature},
  address   = {Basel},
  doi       = {10.1007/s38313-021-0756-6},
  pages     = {58 -- 62},
  year      = {2022},
  abstract  = {In general aviation, too, it is desirable to be able to operate existing internal combustion engines with fuels that produce less CO₂ than Avgas 100LL being widely used today It can be assumed that, in comparison, the fuels CNG, LPG or LNG, which are gaseous under normal conditions, produce significantly lower emissions. Necessary propulsion system adaptations were investigated as part of a research project at Aachen University of Applied Sciences.},
  language  = {en}
}
@article{PeereBlanke2022,
  author    = {Peere, Wouter and Blanke, Tobias},
  title     = {GHEtool: An open-source tool for borefield sizing in Python},
  series = {Journal of Open Source Software},
  volume    = {7},
  journal   = {Journal of Open Source Software},
  number    = {76},
  editor    = {Vernon, Chris},
  issn      = {2475-9066},
  doi       = {10.21105/joss.04406},
  pages     = {1 -- 4, 4406},
  year      = {2022},
  abstract  = {GHEtool is a Python package that contains all the functionalities needed to deal with borefield design. It is developed for both researchers and practitioners. The core of this package is the automated sizing of borefield under different conditions. The sizing of a borefield is typically slow due to the high complexity of the mathematical background. Because this tool has a lot of precalculated data, GHEtool can size a borefield in the order of tenths of milliseconds. This sizing typically takes the order of minutes. Therefore, this tool is suited for being implemented in typical workflows where iterations are required. GHEtool also comes with a graphical user interface (GUI). This GUI is prebuilt as an exe-file because this provides access to all the functionalities without coding. A setup to install the GUI at the user-defined place is also implemented and available at: https://www.mech.kuleuven.be/en/tme/research/thermal_systems/tools/ghetool.},
  language  = {en}
}
@article{GaigallGerstenberg2023,
  author    = {Gaigall, Daniel and Gerstenberg, Julian},
  title     = {Cram{\´e}r-von-Mises tests for the distribution of the excess over a confidence level},
  series = {Journal of Nonparametric Statistics},
  journal   = {Journal of Nonparametric Statistics},
  publisher = {Taylor \& Francis},
  issn      = {1048-5252 (Print)},
  doi       = {10.1080/10485252.2023.2173958},
  year      = {2023},
  abstract  = {The Cram{\´e}r-von-Mises distance is applied to the distribution of the excess over a confidence level. Asymptotics of related statistics are investigated, and it is seen that the obtained limit distributions differ from the classical ones. For that reason, quantiles of the new limit distributions are given and new bootstrap techniques for approximation purposes are introduced and justified. The results motivate new one-sample goodness-of-fit tests for the distribution of the excess over a confidence level and a new confidence interval for the related fitting error. Simulation studies investigate size and power of the tests as well as coverage probabilities of the confidence interval in the finite sample case. A practice-oriented application of the Cram{\´e}r-von-Mises tests is the determination of an appropriate confidence level for the fitting approach. The adoption of the idea to the well-known problem of threshold detection in the context of peaks over threshold modelling is sketched and illustrated by data examples.},
  language  = {en}
}
@article{LiphardtFernandezGonzaloAlbrachtetal.2023,
  author    = {Liphardt, Anna-Maria and Fernandez-Gonzalo, Rodrigo and Albracht, Kirsten and Rittweger, J{\"o}rn and Vico, Laurence},
  title     = {Musculoskeletal research in human space flight - unmet needs for the success of crewed deep space exploration},
  series = {npj Microgravity},
  volume    = {9},
  journal   = {npj Microgravity},
  number    = {Article number: 9},
  publisher = {Springer Nature},
  issn      = {2373-8065},
  doi       = {10.1038/s41526-023-00258-3},
  pages     = {1 -- 9},
  year      = {2023},
  abstract  = {Based on the European Space Agency (ESA) Science in Space Environment (SciSpacE) community White Paper "Human Physiology - Musculoskeletal system", this perspective highlights unmet needs and suggests new avenues for future studies in musculoskeletal research to enable crewed exploration missions. The musculoskeletal system is essential for sustaining physical function and energy metabolism, and the maintenance of health during exploration missions, and consequently mission success, will be tightly linked to musculoskeletal function. Data collection from current space missions from pre-, during-, and post-flight periods would provide important information to understand and ultimately offset musculoskeletal alterations during long-term spaceflight. In addition, understanding the kinetics of the different components of the musculoskeletal system in parallel with a detailed description of the molecular mechanisms driving these alterations appears to be the best approach to address potential musculoskeletal problems that future exploratory-mission crew will face. These research efforts should be accompanied by technical advances in molecular and phenotypic monitoring tools to provide in-flight real-time feedback.},
  language  = {en}
}
@article{RingersBialonskiEgeetal.2023,
  author    = {Ringers, Christa and Bialonski, Stephan and Ege, Mert and Solovev, Anton and Hansen, Jan Niklas and Jeong, Inyoung and Friedrich, Benjamin M. and Jurisch-Yaksi, Nathalie},
  title     = {Novel analytical tools reveal that local synchronization of cilia coincides with tissue-scale metachronal waves in zebrafish multiciliated epithelia},
  series = {eLife},
  volume    = {12},
  journal   = {eLife},
  publisher = {eLife Sciences Publications},
  issn      = {2050-084X},
  doi       = {10.7554/eLife.77701},
  pages     = {27 Seiten},
  year      = {2023},
  abstract  = {Motile cilia are hair-like cell extensions that beat periodically to generate fluid flow along various epithelial tissues within the body. In dense multiciliated carpets, cilia were shown to exhibit a remarkable coordination of their beat in the form of traveling metachronal waves, a phenomenon which supposedly enhances fluid transport. Yet, how cilia coordinate their regular beat in multiciliated epithelia to move fluids remains insufficiently understood, particularly due to lack of rigorous quantification. We combine experiments, novel analysis tools, and theory to address this knowledge gap. To investigate collective dynamics of cilia, we studied zebrafish multiciliated epithelia in the nose and the brain. We focused mainly on the zebrafish nose, due to its conserved properties with other ciliated tissues and its superior accessibility for non-invasive imaging. We revealed that cilia are synchronized only locally and that the size of local synchronization domains increases with the viscosity of the surrounding medium. Even though synchronization is local only, we observed global patterns of traveling metachronal waves across the zebrafish multiciliated epithelium. Intriguingly, these global wave direction patterns are conserved across individual fish, but different for left and right noses, unveiling a chiral asymmetry of metachronal coordination. To understand the implications of synchronization for fluid pumping, we used a computational model of a regular array of cilia. We found that local metachronal synchronization prevents steric collisions, i.e., cilia colliding with each other, and improves fluid pumping in dense cilia carpets, but hardly affects the direction of fluid flow. In conclusion, we show that local synchronization together with tissue-scale cilia alignment coincide and generate metachronal wave patterns in multiciliated epithelia, which enhance their physiological function of fluid pumping.},
  language  = {en}
}
@article{BoehnischBraunMuscarelloetal.2023,
  author    = {B{\"o}hnisch, Nils and Braun, Carsten and Muscarello, Vincenzo and Marzocca, Pier},
  title     = {A sensitivity study on aeroelastic instabilities of slender wings with a large propeller},
  series = {AIAA SCITECH 2023 Forum},
  journal   = {AIAA SCITECH 2023 Forum},
  publisher = {AIAA},
  address   = {Reston, Va.},
  doi       = {10.2514/6.2023-1893},
  pages     = {1 -- 14},
  year      = {2023},
  abstract  = {Next-generation aircraft designs often incorporate multiple large propellers attached along the wingspan. These highly flexible dynamic systems can exhibit uncommon aeroelastic instabilities, which should be carefully investigated to ensure safe operation. The interaction between the propeller and the wing is of particular importance. It is known that whirl flutter is stabilized by wing motion and wing aerodynamics. This paper investigates the effect of a propeller onto wing flutter as a function of span position and mounting stiffness between the propeller and wing. The analysis of a comparison between a tractor and pusher configuration has shown that the coupled system is more stable than the standalone wing for propeller positions near the wing tip for both configurations. The wing fluttermechanism is mostly affected by the mass of the propeller and the resulting change in eigenfrequencies of the wing. For very weak mounting stiffnesses, whirl flutter occurs, which was shown to be stabilized compared to a standalone propeller due to wing motion. On the other hand, the pusher configuration is, as to be expected, the more critical configuration due to the attached mass behind the elastic axis.},
  language  = {de}
}
@article{BergmannMoehrenBraunetal.2023,
  author    = {Bergmann, Ole and M{\"o}hren, Felix and Braun, Carsten and Janser, Frank},
  title     = {On the influence of elasticity on swept propeller noise},
  series = {AIAA SCITECH 2023 Forum},
  journal   = {AIAA SCITECH 2023 Forum},
  publisher = {AIAA},
  address   = {Reston, Va.},
  doi       = {10.2514/6.2023-0210},
  year      = {2023},
  abstract  = {High aerodynamic efficiency requires propellers with high aspect ratios, while propeller sweep potentially reduces noise. Propeller sweep and high aspect ratios increase elasticity and coupling of structural mechanics and aerodynamics, affecting the propeller performance and noise. Therefore, this paper analyzes the influence of elasticity on forward-swept, backward-swept, and unswept propellers in hover conditions. A reduced-order blade element momentum approach is coupled with a one-dimensional Timoshenko beam theory and Farassat's formulation 1A. The results of the aeroelastic simulation are used as input for the aeroacoustic calculation. The analysis shows that elasticity influences noise radiation because thickness and loading noise respond differently to deformations. In the case of the backward-swept propeller, the location of the maximum sound pressure level shifts forward by 0.5 °, while in the case of the forward-swept propeller, it shifts backward by 0.5 °. Therefore, aeroacoustic optimization requires the consideration of propeller deformation.},
  language  = {en}
}
@article{GrossTimmer1998,
  author    = {Groß, Rolf Fritz and Timmer, H.},
  title     = {Energetische und betriebswirtschaftliche Bewertung von K{\"u}hlsystemen f{\"u}r K{\"u}hllager},
  series = {HLH. Heizung, L{\"u}ftung/Klima, Haustechnik},
  volume    = {49},
  journal   = {HLH. Heizung, L{\"u}ftung/Klima, Haustechnik},
  number    = {9},
  publisher = {Springer},
  address   = {D{\"u}sseldorf},
  issn      = {1436-5103},
  pages     = {74 -- 77},
  year      = {1998},
  language  = {de}
}
@article{HerzwurmKramsPietschetal.2012,
  author    = {Herzwurm, Georg and Krams, Benedikt and Pietsch, Wolfram and Schockert, Sixten},
  title     = {Report from the 3rd international workshop on requirements prioritization for customer oriented software development (RePriCo'12)},
  series = {ACM SIGSOFT Software Engineering Notes},
  volume    = {37},
  journal   = {ACM SIGSOFT Software Engineering Notes},
  number    = {4},
  publisher = {Association for Computing Machinery},
  address   = {New York},
  issn      = {0163-5948},
  doi       = {10.1145/2237796.2237817},
  pages     = {32 -- 34},
  year      = {2012},
  abstract  = {Prioritization is an essential task within requirements engineering to cope with complexity and to establish focus properly. The 3rd Workshop on Requirements Prioritization for customer oriented Software Development (RePriCo'12) focused on requirements prioritization and adjacent themes in the context of customer oriented development of bespoke and standard software. Five submissions have been accepted for the proceedings and for presentation. The report summarizes and points out key findings.},
  language  = {en}
}
@article{Pfaff2023,
  author    = {Pfaff, Raphael},
  title     = {Braking distance prediction for vehicle consist in low-speed on-sight operation: a Monte Carlo approach},
  series = {Railway Engineering Science},
  volume    = {31},
  journal   = {Railway Engineering Science},
  number    = {2},
  publisher = {SpringerOpen},
  issn      = {2662-4753 (eISSN)},
  doi       = {10.1007/s40534-023-00303-7},
  pages     = {135 -- 144},
  year      = {2023},
  abstract  = {The first and last mile of a railway journey, in both freight and transit applications, constitutes a high effort and is either non-productive (e.g. in the case of depot operations) or highly inefficient (e.g. in industrial railways). These parts are typically managed on-sight, i.e. with no signalling and train protection systems ensuring the freedom of movement. This is possible due to the rather short braking distances of individual vehicles and shunting consists. The present article analyses the braking behaviour of such shunting units. For this purpose, a dedicated model is developed. It is calibrated on published results of brake tests and validated against a high-definition model for low-speed applications. Based on this model, multiple simulations are executed to obtain a Monte Carlo simulation of the resulting braking distances. Based on the distribution properties and established safety levels, the risk of exceeding certain braking distances is evaluated and maximum braking distances are derived. Together with certain parameters of the system, these can serve in the design and safety assessment of driver assistance systems and automation of these processes.},
  language  = {en}
}
@article{DellmannGloriusLitvinovetal.2023,
  author    = {Dellmann, Sophia Florence and Glorius, J. and Litvinov, Yu A. and Reifarth, R. and Al-Khasawneh, Kafa and Aliotta, M. and Bott, L. and Br{\"u}ckner, Benjamin and Bruno, C. G. and Chen, Ruijiu and Davinson, T. and Dickel, T. and Dillmann, Iris and Dmytriev, D. and Erbacher, P. and Freire-Fern{\´a}ndez, D. and Forstner, Oliver and Geissel, H. and G{\"o}bel, K. and Griffin, Christopher J. and Grisenti, R. and Gumberidze, Alexandre and Haettner, Emma and Hagmann, Siegbert and Heil, M. and Heß, R. and Hillenbrand, P.-M. and Joseph, R. and Jurado, B. and Kozhuharov, Christophor and Kulikov, I. and L{\"o}her, Bastian and Langer, Christoph and Leckenby, Guy and Lederer-Woods, C. and Lestinsky, M. and Litvinov, S. A. and Lorenz, B. A. and Lorenz, E. and Marsh, J. and Menz, Esther Babette and Morgenroth, T. and Petridis, N. and Pibernat, Jerome and Popp, U. and Psaltis, Athanasios and Sanjari, Shahab and Scheidenberger, C. and Sguazzin, M. and Sidhu, Ragandeep Singh and Spillmann, Uwe and Steck, M. and St{\"o}hlker, T. and Surzhykov, A. and Swartz, J. A. and T{\"o}rnqvist, H. and Varga, L. and Vescovi, Diego and Weick, H. and Weigand, M. and Woods, P. and Xing, Y. and Yamaguchi, Taiyo},
  title     = {Proton capture on stored radioactive ¹¹⁸Te ions},
  series = {EPJ Web of Conferences},
  volume    = {279},
  journal   = {EPJ Web of Conferences},
  number    = {Article Number: 11018},
  publisher = {EDP Sciences},
  issn      = {2100-014X},
  doi       = {10.1051/epjconf/202327911018},
  pages     = {1 -- 5},
  year      = {2023},
  abstract  = {Experimental determination of the cross sections of proton capture on radioactive nuclei is extremely difficult. Therefore, it is of substantial interest for the understanding of the production of the p-nuclei. For the first time, a direct measurement of proton-capture cross sections on stored, radioactive ions became possible in an energy range of interest for nuclear astrophysics. The experiment was performed at the Experimental Storage Ring (ESR) at GSI by making use of a sensitive method to measure (p,γ) and (p,n) reactions in inverse kinematics. These reaction channels are of high relevance for the nucleosyn-thesis processes in supernovae, which are among the most violent explosions in the universe and are not yet well understood. The cross section of the ¹¹⁸Te(p,γ) reaction has been measured at energies of 6 MeV/u and 7 MeV/u. The heavy ions interacted with a hydrogen gas jet target. The radiative recombination process of the fully stripped ¹¹⁸Te ions and electrons from the hydrogen target was used as a luminosity monitor. An overview of the experimental method and preliminary results from the ongoing analysis will be presented.},
  language  = {en}
}
@article{BertzMolinnusSchoeningetal.2023,
  author    = {Bertz, Morten and Molinnus, Denise and Sch{\"o}ning, Michael Josef and Homma, Takayuki},
  title     = {Real-time monitoring of H₂O₂ sterilization on individual bacillus atrophaeus spores by optical sensing with trapping Raman spectroscopy},
  series = {Chemosensors},
  volume    = {8},
  journal   = {Chemosensors},
  number    = {11},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2227-9040},
  doi       = {10.3390/chemosensors11080445},
  pages     = {Artikel 445},
  year      = {2023},
  abstract  = {Hydrogen peroxide (H₂O₂), a strong oxidizer, is a commonly used sterilization agent employed during aseptic food processing and medical applications. To assess the sterilization efficiency with H₂O₂, bacterial spores are common microbial systems due to their remarkable robustness against a wide variety of decontamination strategies. Despite their widespread use, there is, however, only little information about the detailed time-resolved mechanism underlying the oxidative spore death by H₂O₂. In this work, we investigate chemical and morphological changes of individual Bacillus atrophaeus spores undergoing oxidative damage using optical sensing with trapping Raman microscopy in real-time. The time-resolved experiments reveal that spore death involves two distinct phases: (i) an initial phase dominated by the fast release of dipicolinic acid (DPA), a major spore biomarker, which indicates the rupture of the spore's core; and (ii) the oxidation of the remaining spore material resulting in the subsequent fragmentation of the spores' coat. Simultaneous observation of the spore morphology by optical microscopy corroborates these mechanisms. The dependence of the onset of DPA release and the time constant of spore fragmentation on H₂O₂ shows that the formation of reactive oxygen species from H₂O₂ is the rate-limiting factor of oxidative spore death.},
  language  = {en}
}
@article{WendlandtKochBritzetal.2023,
  author    = {Wendlandt, Tim and Koch, Claudia and Britz, Beate and Liedek, Anke and Schmidt, Nora and Werner, Stefan and Gleba, Yuri and Vahidpour, Farnoosh and Welden, Melanie and Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {Facile Purification and Use of Tobamoviral Nanocarriers for Antibody-Mediated Display of a Two-Enzyme System},
  series = {Viruses},
  volume    = {9},
  journal   = {Viruses},
  number    = {15},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1999-4915},
  doi       = {doi.org/10.3390/v15091951},
  pages     = {Artikel 1951},
  year      = {2023},
  abstract  = {Immunosorbent turnip vein clearing virus (TVCV) particles displaying the IgG-binding domains D and E of Staphylococcus aureus protein A (PA) on every coat protein (CP) subunit (TVCVPA) were purified from plants via optimized and new protocols. The latter used polyethylene glycol (PEG) raw precipitates, from which virions were selectively re-solubilized in reverse PEG concentration gradients. This procedure improved the integrity of both TVCVPA and the wild-type subgroup 3 tobamovirus. TVCVPA could be loaded with more than 500 IgGs per virion, which mediated the immunocapture of fluorescent dyes, GFP, and active enzymes. Bi-enzyme ensembles of cooperating glucose oxidase and horseradish peroxidase were tethered together on the TVCVPA carriers via a single antibody type, with one enzyme conjugated chemically to its Fc region, and the other one bound as a target, yielding synthetic multi-enzyme complexes. In microtiter plates, the TVCVPA-displayed sugar-sensing system possessed a considerably increased reusability upon repeated testing, compared to the IgG-bound enzyme pair in the absence of the virus. A high coverage of the viral adapters was also achieved on Ta2O5 sensor chip surfaces coated with a polyelectrolyte interlayer, as a prerequisite for durable TVCVPA-assisted electrochemical biosensing via modularly IgG-assembled sensor enzymes.},
  language  = {en}
}
@article{ThulfautGross2000,
  author    = {Thulfaut, Christian and Groß, Rolf Fritz},
  title     = {Experimentelle Untersuchung der Luftstromvermischung in Hybridzellenk{\"u}hlt{\"u}rmen},
  series = {HLH. Heizung, L{\"u}ftung/Klima, Haustechnik},
  volume    = {51},
  journal   = {HLH. Heizung, L{\"u}ftung/Klima, Haustechnik},
  number    = {8},
  publisher = {Springer},
  address   = {D{\"u}sseldorf},
  issn      = {1436-5103},
  pages     = {48 -- 49},
  year      = {2000},
  abstract  = {Zwangsbel{\"u}ftete Nassk{\"u}hlt{\"u}rme haben im Gegensatz zur Trockenk{\"u}hlung bei naßkaltem Wetter Nebelschwaden zur Folge. Dagegen ist bei Naßk{\"u}hlung die spezifische K{\"u}hlleistung durch abgef{\"u}hrte Kondensationsw{\"a}rme h{\"o}her als bei der Trockenk{\"u}hlung. Hybridzellenk{\"u}hlt{\"u}rme kombinieren beide Methoden, so daß ein Mischstrom beider Abluftstr{\"o}me die Wasserdampf-S{\"a}ttigungsgrenze nicht {\"u}berschreitet. Durch das Mischungsverh{\"a}ltnis kann man den gew{\"u}nschten S{\"a}ttigungsgrad einstellen. Je dichter dieser an der S{\"a}ttigungsgrenze liegt, desto h{\"o}her ist die K{\"u}hlleistung. Der von unten zugef{\"u}hrte Luftstrom der Naßk{\"u}hlung und der seitlich zugef{\"u}hrte trockene Abluftstrom m{\"u}ssen sehr gut durchmischt werden, um {\"u}ber den gesamten Austrittsquerschnitt des K{\"u}hlturms die S{\"a}ttigungsgrenze nicht zu {\"u}berschreiten. In einem maßstabsgerechten Modell wurde der Mischungsgrad mit und ohne Einbauten untersucht. {\"U}ber ein Raster von 10 mal 10 Punkten wurde die {\"o}rtliche Temperaturverteilung ermittelt. W{\"a}rmebilanzen ergeben dann die Mischungsg{\"u}te in einer Ebene oberhalb der Zellenkrone. W{\"a}hrend ohne Mischeinbauten der Trockenluftanteil in der Mitte des Querschnitts bei unter 15 \% liegt erh{\"o}hen Einbauten den Trockenluftanteil auf 30 \% bis {\"u}ber 40 \%. Dabei wurde die Trockenluft auf jeder K{\"u}hlturmseite durch 4 konisch zulaufende, unten offene und oben geschlitzte Einbauten kanalisiert. Die Nassluft wurde durch eine im Querschnitt dreieckige Rinne in Richtung der Trockenluftausl{\"a}sse umgelenkt. Im Raster leicht zu lokalisierende Abweichungen vom gew{\"u}nschten Mittelwert zeigen Potential f{\"u}r die weitere Verbesserung der Einbauten.},
  language  = {de}
}
@article{KowalewskiBragardHueningetal.2023,
  author    = {Kowalewski, Paul and Bragard, Michael and H{\"u}ning, Felix and De Doncker, Rik W.},
  title     = {An inexpensive Wiegand-sensor-based rotary encoder without rotating magnets for use in electrical drives},
  series = {IEEE Transactions on Instrumentation and Measurement},
  journal   = {IEEE Transactions on Instrumentation and Measurement},
  publisher = {IEEE},
  issn      = {0018-9456 (Print)},
  doi       = {10.1109/TIM.2023.3326166},
  pages     = {10 Seiten},
  year      = {2023},
  abstract  = {This paper introduces an inexpensive Wiegand-sensor-based rotary encoder that avoids rotating magnets and is suitable for electrical-drive applications. So far, Wiegand-sensor-based encoders usually include a magnetic pole wheel with rotating permanent magnets. These encoders combine the disadvantages of an increased magnet demand and a limited maximal speed due to the centripetal force acting on the rotating magnets. The proposed approach reduces the total demand of permanent magnets drastically. Moreover, the rotating part is manufacturable from a single piece of steel, which makes it very robust and cheap. This work presents the theoretical operating principle of the proposed approach and validates its benefits on a hardware prototype. The presented proof-of-concept prototype achieves a mechanical resolution of 4.5 ° by using only 4 permanent magnets, 2Wiegand sensors and a rotating steel gear wheel with 20 teeth.},
  language  = {en}
}
@article{HerssensCowburnAlbrachtetal.2022,
  author    = {Herssens, Nolan and Cowburn, James and Albracht, Kirsten and Braunstein, Bjoern and Cazzola, Dario and Colyer, Steffi and Minetti, Alberto E. and Pavei, Gaspare and Rittweger, J{\"o}rn and Weber, Tobias and Green, David A.},
  title     = {Movement in low gravity environments (MoLo) programme - the MoLo-L.O.O.P. study protocol},
  series = {PLOS ONE / Public Library of Science},
  volume    = {17},
  journal   = {PLOS ONE / Public Library of Science},
  number    = {11},
  editor    = {Cattaneo, Luigi},
  publisher = {Plos},
  address   = {San Francisco},
  issn      = {1932-6203},
  doi       = {10.1371/journal.pone.0278051},
  pages     = {e0278051},
  year      = {2022},
  abstract  = {Exposure to prolonged periods in microgravity is associated with deconditioning of the musculoskeletal system due to chronic changes in mechanical stimulation. Given astronauts will operate on the Lunar surface for extended periods of time, it is critical to quantify both external (e.g., ground reaction forces) and internal (e.g., joint reaction forces) loads of relevant movements performed during Lunar missions. Such knowledge is key to predict musculoskeletal deconditioning and determine appropriate exercise countermeasures associated with extended exposure to hypogravity.},
  language  = {en}
}
@article{GrossBerger2005,
  author    = {Groß, Rolf Fritz and Berger, J.},
  title     = {Quo Vadis - Ausblick in die Geb{\"a}udeleittechnik der Zukunft},
  series = {HLH. Heizung, L{\"u}ftung/Klima, Haustechnik},
  volume    = {56},
  journal   = {HLH. Heizung, L{\"u}ftung/Klima, Haustechnik},
  number    = {1},
  publisher = {Springer},
  address   = {D{\"u}sseldorf},
  issn      = {1436-5103},
  pages     = {39 -- 41},
  year      = {2005},
  abstract  = {Auf dem Weg zum vernetzten Haus stoßen Hersteller und Planer, insbesondere im privaten Wohnungsbau, zur Zeit noch auf erhebliche Widerst{\"a}nde bei der Durchdringung des Marktes.},
  language  = {de}
}