@article{StaeudleSeynnesLapsetal.2022,
  author    = {St{\"a}udle, Benjamin and Seynnes, Olivier and Laps, Guido and Br{\"u}ggemann, Gert-Peter and Albracht, Kirsten},
  title     = {Altered gastrocnemius contractile behavior in former achilles tendon rupture patients during walking},
  series = {Frontiers in Physiology},
  volume    = {13},
  journal   = {Frontiers in Physiology},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1664-042X},
  doi       = {10.3389/fphys.2022.792576},
  pages     = {12 Seiten},
  year      = {2022},
  abstract  = {Achilles tendon rupture (ATR) remains associated with functional limitations years after injury. Architectural remodeling of the gastrocnemius medialis (GM) muscle is typically observed in the affected leg and may compensate force deficits caused by a longer tendon. Yet patients seem to retain functional limitations during—low-force—walking gait. To explore the potential limits imposed by the remodeled GM muscle-tendon unit (MTU) on walking gait, we examined the contractile behavior of muscle fascicles during the stance phase. In a cross-sectional design, we studied nine former patients (males; age: 45 ± 9 years; height: 180 ± 7 cm; weight: 83 ± 6 kg) with a history of complete unilateral ATR, approximately 4 years post-surgery. Using ultrasonography, GM tendon morphology, muscle architecture at rest, and fascicular behavior were assessed during walking at 1.5 m⋅s-1 on a treadmill. Walking patterns were recorded with a motion capture system. The unaffected leg served as control. Lower limbs kinematics were largely similar between legs during walking. Typical features of ATR-related MTU remodeling were observed during the stance sub-phases corresponding to series elastic element (SEE) lengthening (energy storage) and SEE shortening (energy release), with shorter GM fascicles (36 and 36\%, respectively) and greater pennation angles (8° and 12°, respectively). However, relative to the optimal fascicle length for force production, fascicles operated at comparable length in both legs. Similarly, when expressed relative to optimal fascicle length, fascicle contraction velocity was not different between sides, except at the time-point of peak series elastic element (SEE) length, where it was 39 ± 49\% lower in the affected leg. Concomitantly, fascicles rotation during contraction was greater in the affected leg during the whole stance-phase, and architectural gear ratios (AGR) was larger during SEE lengthening. Under the present testing conditions, former ATR patients had recovered a relatively symmetrical walking gait pattern. Differences in seen AGR seem to accommodate the profound changes in MTU architecture, limiting the required fascicle shortening velocity. Overall, the contractile behavior of the GM fascicles does not restrict length- or velocity-dependent force potentials during this locomotor task.},
  language  = {en}
}
@article{RichterBraunsteinStaeudleetal.2021,
  author    = {Richter, Charlotte and Braunstein, Bjoern and St{\"a}udle, Benjamin and Attias, Julia and Suess, Alexander and Weber, Tobias and Mileva, Katja N. and Rittweger, Joern and Green, David A. and Albracht, Kirsten},
  title     = {Gastrocnemius medialis contractile behavior is preserved during 30\% body weight supported gait training},
  series = {Frontiers in Sports and Active Living},
  volume    = {2021},
  journal   = {Frontiers in Sports and Active Living},
  number    = {2},
  publisher = {Frontiers},
  address   = {Lausanne},
  issn      = {2624-9367},
  doi       = {10.3389/fspor.2020.614559},
  pages     = {Artikel 614559},
  year      = {2021},
  abstract  = {Rehabilitative body weight supported gait training aims at restoring walking function as a key element in activities of daily living. Studies demonstrated reductions in muscle and joint forces, while kinematic gait patterns appear to be preserved with up to 30\% weight support. However, the influence of body weight support on muscle architecture, with respect to fascicle and series elastic element behavior is unknown, despite this having potential clinical implications for gait retraining. Eight males (31.9 ± 4.7 years) walked at 75\% of the speed at which they typically transition to running, with 0\% and 30\% body weight support on a lower-body positive pressure treadmill. Gastrocnemius medialis fascicle lengths and pennation angles were measured via ultrasonography. Additionally, joint kinematics were analyzed to determine gastrocnemius medialis muscle-tendon unit lengths, consisting of the muscle's contractile and series elastic elements. Series elastic element length was assessed using a muscle-tendon unit model. Depending on whether data were normally distributed, a paired t-test or Wilcoxon signed rank test was performed to determine if body weight supported walking had any effects on joint kinematics and fascicle-series elastic element behavior. Walking with 30\% body weight support had no statistically significant effect on joint kinematics and peak series elastic element length. Furthermore, at the time when peak series elastic element length was achieved, and on average across the entire stance phase, muscle-tendon unit length, fascicle length, pennation angle, and fascicle velocity were unchanged with respect to body weight support. In accordance with unchanged gait kinematics, preservation of fascicle-series elastic element behavior was observed during walking with 30\% body weight support, which suggests transferability of gait patterns to subsequent unsupported walking.},
  language  = {en}
}
@article{QuittmannAbelAlbrachtetal.2022,
  author    = {Quittmann, Oliver J. and Abel, Thomas and Albracht, Kirsten and Str{\"u}der, Heiko K.},
  title     = {Biomechanics of all-out handcycling exercise: kinetics, kinematics and muscular activity of a 15-s sprint test in able-bodied participants},
  series = {Sports Biomechanics},
  volume    = {21},
  journal   = {Sports Biomechanics},
  number    = {10},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {1752-6116 (Onlineausgabe)},
  doi       = {10.1080/14763141.2020.1745266},
  pages     = {1200 -- 1223},
  year      = {2022},
  abstract  = {This study aims to quantify the kinematics, kinetics and muscular activity of all-out handcycling exercise and examine their alterations during the course of a 15-s sprint test. Twelve able-bodied competitive triathletes performed a 15-s all-out sprint test in a recumbent racing handcycle that was attached to an ergometer. During the sprint test, tangential crank kinetics, 3D joint kinematics and muscular activity of 10 muscles of the upper extremity and trunk were examined using a power metre, motion capturing and surface electromyography (sEMG), respectively. Parameters were compared between revolution one (R1), revolution two (R2), the average of revolution 3 to 13 (R3) and the average of the remaining revolutions (R4). Shoulder abduction and internal-rotation increased, whereas maximal shoulder retroversion decreased during the sprint. Except for the wrist angles, angular velocity increased for every joint of the upper extremity. Several muscles demonstrated an increase in muscular activation, an earlier onset of muscular activation in crank cycle and an increased range of activation. During the course of a 15-s all-out sprint test in handcycling, the shoulder muscles and the muscles associated to the push phase demonstrate indications for short-duration fatigue. These findings are helpful to prevent injuries and improve performance in all-out handcycling.},
  language  = {en}
}
@article{RichterBraunsteinStaeudleetal.2021,
  author    = {Richter, Charlotte and Braunstein, Bj{\"o}rn and St{\"a}udle, Benjamin and Attias, Julia and S{\"u}ss, Alexander and Weber, Tobias and Mileva, Katya N. and Rittweger, J{\"o}rn and Green, David A. and Albracht, Kirsten},
  title     = {Gastrocnemius medialis contractile behavior during running differs between simulated Lunar and Martian gravities},
  series = {Scientific reports},
  volume    = {11},
  journal   = {Scientific reports},
  number    = {Article number: 22555},
  publisher = {Springer Nature},
  address   = {London},
  issn      = {2045-2322},
  doi       = {10.1038/s41598-021-00527-9},
  pages     = {13 Seiten},
  year      = {2021},
  abstract  = {The international partnership of space agencies has agreed to proceed forward to the Moon sustainably. Activities on the Lunar surface (0.16 g) will allow crewmembers to advance the exploration skills needed when expanding human presence to Mars (0.38 g). Whilst data from actual hypogravity activities are limited to the Apollo missions, simulation studies have indicated that ground reaction forces, mechanical work, muscle activation, and joint angles decrease with declining gravity level. However, these alterations in locomotion biomechanics do not necessarily scale to the gravity level, the reduction in gastrocnemius medialis activation even appears to level off around 0.2 g, while muscle activation pattern remains similar. Thus, it is difficult to predict whether gastrocnemius medialis contractile behavior during running on Moon will basically be the same as on Mars. Therefore, this study investigated lower limb joint kinematics and gastrocnemius medialis behavior during running at 1 g, simulated Martian gravity, and simulated Lunar gravity on the vertical treadmill facility. The results indicate that hypogravity-induced alterations in joint kinematics and contractile behavior still persist between simulated running on the Moon and Mars. This contrasts with the concept of a ceiling effect and should be carefully considered when evaluating exercise prescriptions and the transferability of locomotion practiced in Lunar gravity to Martian gravity.},
  language  = {en}
}
@article{WerkhausenWillwacherAlbracht2021,
  author    = {Werkhausen, Amelie and Willwacher, Steffen and Albracht, Kirsten},
  title     = {Medial gastrocnemius muscle fascicles shorten throughout stance during sprint acceleration},
  series = {Scandinavian Journal of Medicine \& Science in Sports},
  volume    = {31},
  journal   = {Scandinavian Journal of Medicine \& Science in Sports},
  number    = {7},
  publisher = {Wiley-Blackwell},
  address   = {Oxford},
  issn      = {0905-7188 (Druckausgabe)},
  doi       = {10.1111/sms.13956},
  pages     = {1471 -- 1480},
  year      = {2021},
  abstract  = {The compliant nature of distal limb muscle-tendon units is traditionally considered suboptimal in explosive movements when positive joint work is required. However, during accelerative running, ankle joint net mechanical work is positive. Therefore, this study aims to investigate how plantar flexor muscle-tendon behavior is modulated during fast accelerations. Eleven female sprinters performed maximum sprint accelerations from starting blocks, while gastrocnemius muscle fascicle lengths were estimated using ultrasonography. We combined motion analysis and ground reaction force measurements to assess lower limb joint kinematics and kinetics, and to estimate gastrocnemius muscle-tendon unit length during the first two acceleration steps. Outcome variables were resampled to the stance phase and averaged across three to five trials. Relevant scalars were extracted and analyzed using one-sample and two-sample t-tests, and vector trajectories were compared using statistical parametric mapping. We found that an uncoupling of muscle fascicle behavior from muscle-tendon unit behavior is effectively used to produce net positive mechanical work at the joint during maximum sprint acceleration. Muscle fascicles shortened throughout the first and second steps, while shortening occurred earlier during the first step, where negative joint work was lower compared with the second step. Elastic strain energy may be stored during dorsiflexion after touchdown since fascicles did not lengthen at the same time to dissipate energy. Thus, net positive work generation is accommodated by the reuse of elastic strain energy along with positive gastrocnemius fascicle work. Our results show a mechanism of how muscles with high in-series compliance can contribute to net positive joint work.},
  language  = {en}
}
@article{MontiWaldvogelRitzmannetal.2021,
  author    = {Monti, Elena and Waldvogel, Janice and Ritzmann, Ramona and Freyler, Kathrin and Albracht, Kirsten and Helm, Michael and De Cesare, Niccol{\`o} and Pavan, Piero and Reggiani, Carlo and Gollhofer, Albert and Narici, Marco Vincenzo},
  title     = {Muscle in variable gravity: "I do not know where I am, but I know what to do"},
  series = {Frontiers in Physiology},
  volume    = {12},
  journal   = {Frontiers in Physiology},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1664-042X},
  doi       = {10.3389/fphys.2021.714655},
  pages     = {19 Seiten},
  year      = {2021},
  abstract  = {Performing tasks, such as running and jumping, requires activation of the agonist and antagonist muscles before (motor unit pre-activation) and during movement performance (Santello and Mcdonagh, 1998). A well-timed and regulated muscle activation elicits a stretch-shortening cycle (SSC) response, naturally occurring in bouncing movements (Ishikawa and Komi, 2004; Taube et al., 2012). By definition, the SSC describes the stretching of a pre-activated muscle-tendon complex immediately followed by a muscle shortening in the concentric push-off phase (Komi, 1984). Given the importance of SSC actions for human movement, it is not surprising that many studies investigated the biomechanics of this phenomenon; in particular, drop jumps (DJs) represent a good paradigm to study muscle fascicle and tendon behavior in ballistic movements involving the SSC. Within a DJ, three main phases [pre-activation, braking, and push-off (PO; Komi, 2000)] have been recognized and extensively studied in common and challenging conditions, such as changes in load, falling height, or simulated hypo-gravity (Avela et al., 1994; Arampatzis et al., 2001; Fukashiro et al., 2005; Ishikawa et al., 2005; Sousa et al., 2007; Ritzmann et al., 2016; Helm et al., 2020). These studies show that the timing and amount of triceps-surae muscle-tendon unit pre-activation in DJs are differentially regulated based on the load applied to the muscle, being optimal in normal "Earth" gravity conditions (Avela et al., 1994), but decreased in simulated hypo-gravity, hyper-gravity (Avela et al., 1994; Ritzmann et al., 2016), or unknown conditions (i.e., unknown falling heights; Helm et al., 2020). Some authors indicated that, when falling from heights different from the optimal one [defined as the drop height giving a maximum DJ performance indicated as peak ground reaction force (GRF) or jump high], electromyographic (EMG) activity of the plantar flexors increases from lower than optimal to higher than optimal heights (Ishikawa and Komi, 2004; Sousa et al., 2007). These findings highlight the ability of the central nervous system to regulate the timing and amount of pre-activation according to different jumping conditions, thus regulating muscle fascicle length, tendon and joint stiffness as well as position, in order to safely land on the ground and quickly re-bounce. Similarly, to pre-activation, also in the braking phase, the plantar flexors are differentially regulated. In optimal height (i.e., load) jumping conditions, gastrocnemius medialis (GM) fascicles shorten at early ground contact (possibly due to the intervention of the stretch reflex; Gollhofer et al., 1992) and behave quasi-isometrically in the late braking phase, enabling tendon elongation, and storage of elastic energy (Gollhofer et al., 1992; Fukashiro et al., 2005; Sousa et al., 2007). When increasing the falling height (augmenting the impact GRF), the quasi-isometric behavior of fascicles disappears, and fast fascicle lengthening occurs (Ishikawa et al., 2005; Sousa et al., 2007). In the third and last PO phase, fascicles shorten and the tendon releases the elastic energy previously stored. Bobbert et al. (1987) reported no influence of jumping height on the work done and on the net vertical impulse assessed during PO; this observation suggests that, despite an optimal DJ performance might be achieved only in specific conditions (falling heights, loads), the central nervous system seems to be able to regulate muscle behavior in order to effectively perform the required task also in challenging situations. Although the regulation of triceps-surae muscle-tendon unit in DJs has been extensively investigated, very few studies focused on sarcomeres behavior during the performance of this SSC movement (Kurokawa et al., 2003; Fukashiro et al., 2005, 2006). Sarcomeres represent muscle contractile units and are known to express different amounts of force depending on their length (Gordon et al., 1966; Walker and Schrodt, 1974); thus, understanding the time course of their responses during DJs is fundamental to gain further insights into muscle force-generating capacity. In vivo measurement of sarcomere length in humans has been so far been performed only in static positions and under highly controlled experimental conditions (Llewellyn et al., 2008; Sanchez et al., 2015). Instead, human sarcomere length estimation (achieved by dividing GM measured fascicle length for a fixed sarcomere number) in dynamic contractions provided an indirect measure of sarcomere operating range during squat jump, countermovement jump, and DJ (Fukashiro et al., 2005, 2006; Kurokawa et al., 2003). The results of these studies showed that sarcomeres operate in the ascending limb of their length-tension (L-T) relationship in all types of jumps, and particularly so in DJ. However, most of the available observations on sarcomere and muscle fascicle behavior were made in condition of constant gravity. Thus, in order to understand how sarcomere and muscle fascicle length are regulated in variable gravity conditions, we performed experiments in a parabolic flight, involving variable gravity levels, ranging from about zero-g to about double the Earth's gravity (1 g; Waldvogel et al., 2021). Specifically, the aims of the present study were as follows: 1. To investigate the ability of the neuromuscular system in regulating fascicle length in response to conditions of variable gravity. 2. To estimate sarcomere operative length in the different DJ phases, in order to calculate its theoretical force production and its possible modulation in conditions of variable gravity. We hypothesized that muscle fascicles would be differentially regulated in different gravity conditions compared to 1 g, particularly in anticipation of landing and re-bouncing in unknown gravity levels. In addition, we hypothesized that sarcomeres would operate in the upper part of the ascending limb of their L-T relationship, possibly lengthening during the braking phase (especially in hyper-gravity) while operating quasi-isometrically in 1 g.},
  language  = {en}
}
@article{StaeudleSeynnesLapsetal.2021,
  author    = {St{\"a}udle, Benjamin and Seynnes, Olivier and Laps, Guido and G{\"o}ll, Fabian and Br{\"u}ggemann, Gert-Peter and Albracht, Kirsten},
  title     = {Recovery from achilles tendon repair: a combination of Postsurgery Outcomes and Insufficient remodeling of muscle and tendon},
  series = {Medicine \& Science in Sports \& Exercise},
  volume    = {53},
  journal   = {Medicine \& Science in Sports \& Exercise},
  number    = {7},
  publisher = {American College of Sports Medicine},
  address   = {Philadelphia, Pa.},
  issn      = {1530-0315},
  doi       = {10.1249/MSS.0000000000002592},
  pages     = {1356 -- 1366},
  year      = {2021},
  abstract  = {Achilles tendon rupture (ATR) patients have persistent functional deficits in the triceps surae muscle-tendon unit (MTU). The complex remodeling of the MTU accompanying these deficits remains poorly understood. The purpose of the present study was to associate in vivo and in silico data to investigate the relations between changes inMTU properties and strength deficits inATR patients. Methods: Elevenmale subjects who had undergone surgical repair of complete unilateral ATR were examined 4.6 ± 2.0 (mean ± SD) yr after rupture. Gastrocnemius medialis (GM) tendon stiffness, morphology, and muscle architecture were determined using ultrasonography. The force-length relation of the plantar flexor muscles was assessed at five ankle joint angles. In addition, simulations (OpenSim) of the GM MTU force-length properties were performed with various iterations of MTU properties found between the unaffected and the affected side. Results: The affected side of the patients displayed a longer, larger, and stiffer GM tendon (13\% ± 10\%, 105\% ± 28\%, and 54\% ± 24\%, respectively) compared with the unaffected side. The GM muscle fascicles of the affected side were shorter (32\% ± 12\%) and with greater pennation angles (31\% ± 26\%). A mean deficit in plantarflexion moment of 31\% ± 10\% was measured. Simulations indicate that pairing an intact muscle with a longer tendon shifts the optimal angular range of peak force outside physiological angular ranges, whereas the shorter muscle fascicles and tendon stiffening seen in the affected side decrease this shift, albeit incompletely. Conclusions: These results suggest that the substantial changes in MTU properties found in ATR patients may partly result from compensatory remodeling, although this process appears insufficient to fully restore muscle function.},
  language  = {en}
}
@article{SavitskayaZhantlessovaKistaubayevaetal.2023,
  author    = {Savitskaya, Irina and Zhantlessova, Sirina and Kistaubayeva, Aida and Ignatova, Ludmila and Shokatayeva, Dina and Sinyavsky, Yuriy and Kushugulova, Almagul and Digel, Ilya},
  title     = {Prebiotic cellulose-pullulan matrix as a "vehicle" for probiotic biofilm delivery to the host large intestine},
  series = {Polymers},
  journal   = {Polymers},
  number    = {16(1)},
  publisher = {MDPI},
  address   = {Basel},
  doi       = {10.3390/polym16010030},
  pages     = {Artikel 30},
  year      = {2023},
  abstract  = {This study describes the development of a new combined polysaccharide-matrix-based technology for the immobilization of Lactobacillus rhamnosus GG (LGG) bacteria in biofilm form. The new composition allows for delivering the bacteria to the digestive tract in a manner that improves their robustness compared with planktonic cells and released biofilm cells. Granules consisting of a polysaccharide matrix with probiotic biofilms (PMPB) with high cell density (>9 log CFU/g) were obtained by immobilization in the optimized nutrient medium. Successful probiotic loading was confirmed by fluorescence microscopy and scanning electron microscopy. The developed prebiotic polysaccharide matrix significantly enhanced LGG viability under acidic (pH 2.0) and bile salt (0.3\%) stress conditions. Enzymatic extract of feces, mimicking colon fluid in terms of cellulase activity, was used to evaluate the intestinal release of probiotics. PMPB granules showed the ability to gradually release a large number of viable LGG cells in the model colon fluid. In vivo, the oral administration of PMPB granules in rats resulted in the successful release of probiotics in the colon environment. The biofilm-forming incubation method of immobilization on a complex polysaccharide matrix tested in this study has shown high efficacy and promising potential for the development of innovative biotechnologies.},
  language  = {en}
}
@article{WerkhausenAlbrachtCroninetal.2018,
  author    = {Werkhausen, Amelie and Albracht, Kirsten and Cronin, Neil J and Paulsen, G{\o}ran and Bojsen-M{\o}ller, Jens and Seynnes, Olivier R},
  title     = {Effect of training-induced changes in achilles tendon stiffness on muscle-tendon behavior during landing},
  series = {Frontiers in physiology},
  journal   = {Frontiers in physiology},
  number    = {9},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1664-042X},
  doi       = {10.3389/fphys.2018.00794},
  pages     = {11 Seiten},
  year      = {2018},
  abstract  = {During rapid deceleration of the body, tendons buffer part of the elongation of the muscle-tendon unit (MTU), enabling safe energy dissipation via eccentric muscle contraction. Yet, the influence of changes in tendon stiffness within the physiological range upon these lengthening contractions is unknown. This study aimed to examine the effect of training-induced stiffening of the Achilles tendon on triceps surae muscle-tendon behavior during a landing task. Twenty-one male subjects were assigned to either a 10-week resistance-training program consisting of single-leg isometric plantarflexion (n = 11) or to a non-training control group (n = 10). Before and after the training period, plantarflexion force, peak Achilles tendon strain and stiffness were measured during isometric contractions, using a combination of dynamometry, ultrasound and kinematics data. Additionally, testing included a step-landing task, during which joint mechanics and lengths of gastrocnemius and soleus fascicles, Achilles tendon, and MTU were determined using synchronized ultrasound, kinematics and kinetics data collection. After training, plantarflexion strength and Achilles tendon stiffness increased (15 and 18\%, respectively), and tendon strain during landing remained similar. Likewise, lengthening and negative work produced by the gastrocnemius MTU did not change detectably. However, in the training group, gastrocnemius fascicle length was offset (8\%) to a longer length at touch down and, surprisingly, fascicle lengthening and velocity were reduced by 27 and 21\%, respectively. These changes were not observed for soleus fascicles when accounting for variation in task execution between tests. These results indicate that a training-induced increase in tendon stiffness does not noticeably affect the buffering action of the tendon when the MTU is rapidly stretched. Reductions in gastrocnemius fascicle lengthening and lengthening velocity during landing occurred independently from tendon strain. Future studies are required to provide insight into the mechanisms underpinning these observations and their influence on energy dissipation.},
  language  = {en}
}
@article{HaegerJolmesOyenetal.2024,
  author    = {Haeger, Gerrit and Jolmes, Tristan and Oyen, Sven and Jaeger, Karl-Erich and Bongaerts, Johannes and Sch{\"o}rken, Ulrich and Siegert, Petra},
  title     = {Novel recombinant aminoacylase from Paraburkholderia monticola capable of N-acyl-amino acid synthesis},
  series = {Applied Microbiology and Biotechnology},
  journal   = {Applied Microbiology and Biotechnology},
  number    = {108},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1432-0614},
  doi       = {10.1007/s00253-023-12868-8},
  pages     = {14 Seiten},
  year      = {2024},
  abstract  = {N-Acyl-amino acids can act as mild biobased surfactants, which are used, e.g., in baby shampoos. However, their chemical synthesis needs acyl chlorides and does not meet sustainability criteria. Thus, the identification of biocatalysts to develop greener synthesis routes is desirable. We describe a novel aminoacylase from Paraburkholderia monticola DSM 100849 (PmAcy) which was identified, cloned, and evaluated for its N-acyl-amino acid synthesis potential. Soluble protein was obtained by expression in lactose autoinduction medium and co-expression of molecular chaperones GroEL/S. Strep-tag affinity purification enriched the enzyme 16-fold and yielded 15 mg pure enzyme from 100 mL of culture. Biochemical characterization revealed that PmAcy possesses beneficial traits for industrial application like high temperature and pH-stability. A heat activation of PmAcy was observed upon incubation at temperatures up to 80 °C. Hydrolytic activity of PmAcy was detected with several N-acyl-amino acids as substrates and exhibited the highest conversion rate of 773 U/mg with N-lauroyl-L-alanine at 75 °C. The enzyme preferred long-chain acyl-amino-acids and displayed hardly any activity with acetyl-amino acids. PmAcy was also capable of N-acyl-amino acid synthesis with good conversion rates. The best synthesis results were obtained with the cationic L-amino acids L-arginine and L-lysine as well as with L-leucine and L-phenylalanine. Exemplarily, L-phenylalanine was acylated with fatty acids of chain lengths from C8 to C18 with conversion rates of up to 75\%. N-lauroyl-L-phenylalanine was purified by precipitation, and the structure of the reaction product was verified by LC-MS and NMR.},
  language  = {en}
}
@article{YangKriechbaumerAlbrachtetal.2014,
  author    = {Yang, Peng-Fei and Kriechbaumer, Andreas and Albracht, Kirsten and Sanno, Maximilian and Ganse, Bergita and Koy, Timmo and Shang, Peng and br{\"u}ggemann, Gert-Peter and M{\"u}ller, Lars Peter and Rittweger, J{\"o}rn},
  title     = {A novel optical approach for assessing in vivo bone segment deformation and its application in muscle-bone relationship studies in humans},
  series = {Journal of Orthopaedic Translation},
  volume    = {2},
  journal   = {Journal of Orthopaedic Translation},
  number    = {4},
  publisher = {Elsevier},
  address   = {Singapore},
  issn      = {2214-0328},
  doi       = {10.1016/j.jot.2014.07.078},
  pages     = {238 -- 238},
  year      = {2014},
  language  = {en}
}
@article{vonHaefenKrautwaldStolleetal.2022,
  author    = {von H{\"a}fen, Hajo and Krautwald, Clemens and Stolle, Jacob and Bung, Daniel Bernhard and Goseberg, Nils},
  title     = {Overland flow of broken solitary waves over a two-dimensional coastal plane},
  series = {Coastal Engineering},
  volume    = {175},
  journal   = {Coastal Engineering},
  number    = {August},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1872-7379},
  doi       = {10.1016/j.coastaleng.2022.104125},
  pages     = {14 Seiten},
  year      = {2022},
  abstract  = {Landslides, rock falls or related subaerial and subaqueous mass slides can generate devastating impulse waves in adjacent waterbodies. Such waves can occur in lakes and fjords, or due to glacier calving in bays or at steep ocean coastlines. Infrastructure and residential houses along coastlines of those waterbodies are often situated on low elevation terrain, and are potentially at risk from inundation. Impulse waves, running up a uniform slope and generating an overland flow over an initially dry adjacent horizontal plane, represent a frequently found scenario, which needs to be better understood for disaster planning and mitigation. This study presents a novel set of large-scale flume test focusing on solitary waves propagating over a 1:14.5 slope and breaking onto a horizontal section. Examining the characteristics of overland flow, this study gives, for the first time, insight into the fundamental process of overland flow of a broken solitary wave: its shape and celerity, as well as its momentum when wave breaking has taken place beforehand.},
  language  = {en}
}
@article{MarinkovicButenweg2022,
  author    = {Marinkovic, Marko and Butenweg, Christoph},
  title     = {Numerical analysis of the in-plane behaviour of decoupled masonry infilled RC frames},
  series = {Engineering Structures},
  volume    = {272},
  journal   = {Engineering Structures},
  number    = {1},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0141-0296},
  doi       = {10.1016/j.engstruct.2022.114959},
  pages     = {18 Seiten},
  year      = {2022},
  abstract  = {Damage of reinforced concrete (RC) frames with masonry infill walls has been observed after many earthquakes. Brittle behaviour of the masonry infills in combination with the ductile behaviour of the RC frames makes infill walls prone to damage during earthquakes. Interstory deformations lead to an interaction between the infill and the RC frame, which affects the structural response. The result of this interaction is significant damage to the infill wall and sometimes to the surrounding structural system too. In most design codes, infill walls are considered as non-structural elements and neglected in the design process, because taking into account the infills and considering the interaction between frame and infill in software packages can be complicated and impractical. A good way to avoid negative aspects arising from this behavior is to ensure no or low-interaction of the frame and infill wall, for instance by decoupling the infill from the frame. This paper presents the numerical study performed to investigate new connection system called INODIS (Innovative Decoupled Infill System) for decoupling infill walls from surrounding frame with the aim to postpone infill activation to high interstory drifts thus reducing infill/frame interaction and minimizing damage to both infills and frames. The experimental results are first used for calibration and validation of the numerical model, which is then employed for investigating the influence of the material parameters as well as infill's and frame's geometry on the in-plane behaviour of the infilled frames with the INODIS system. For all the investigated situations, simulation results show significant improvements in behaviour for decoupled infilled RC frames in comparison to the traditionally infilled frames.},
  language  = {en}
}
@article{GiresiniSassuButenwegetal.2017,
  author    = {Giresini, Linda and Sassu, Mauro and Butenweg, Christoph and Alecci, Valerio and De Stefano, Mario},
  title     = {Vault macro-element with equivalent trusses in global seismic analyses},
  series = {Earthquakes and Structures},
  volume    = {12},
  journal   = {Earthquakes and Structures},
  number    = {4},
  publisher = {Techno-Press},
  address   = {Taejŏn},
  issn      = {2092-7614 (Print)},
  doi       = {10.12989/eas.2017.12.4.409},
  pages     = {409 -- 423},
  year      = {2017},
  abstract  = {This paper proposes a quick and simplified method to describe masonry vaults in global seismic analyses of buildings. An equivalent macro-element constituted by a set of six trusses, two for each transverse, longitudinal and diagonal direction, is introduced. The equivalent trusses, whose stiffness is calculated by fully modeled vaults of different geometry, mechanical properties and boundary conditions, simulate the vault in both global analysis and local analysis, such as kinematic or rocking approaches. A parametric study was carried out to investigate the influence of geometrical characteristics and mechanical features on the equivalent stiffness values. The method was numerically validated by performing modal and transient analysis on a three naves-church in the elastic range. Vibration modes and displacement time-histories were compared showing satisfying agreement between the complete and the simplified models. This procedure is particularly useful in engineering practice because it allows to assess, in a simplified way, the effectiveness of strengthening interventions for reducing horizontal relative displacements between vault supports.},
  language  = {en}
}
@article{ButenwegHeuerWenk2015,
  author    = {Butenweg, Christoph and Heuer, R. and Wenk, T.},
  title     = {Erdbebeningenieurwesen und Baudynamik},
  series = {Bauingenieur},
  volume    = {90},
  journal   = {Bauingenieur},
  number    = {10},
  publisher = {VDI Fachmedien},
  address   = {D{\"u}sseldorf},
  issn      = {00056650},
  pages     = {S1},
  year      = {2015},
  language  = {de}
}
@article{BeckerFrauenrathHezeletal.2010,
  author    = {Becker, Meike and Frauenrath, Tobias and Hezel, Fabian and Krombach, Gabriele A. and Kremer, Ute and Koppers, Benedikt and Butenweg, Christoph and Goemmel, Andreas and Utting, Jane F. and Schulz-Menger, Jeanette and Niendorf, Thoralf},
  title     = {Comparison of left ventricular function assessment using phonocardiogram- and electrocardiogram-triggered 2D SSFP CINE MR imaging at 1.5 T and 3.0 T},
  series = {European Radiology},
  volume    = {20},
  journal   = {European Radiology},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1432-1084 (Onlineausgabe)},
  doi       = {10.1007/s00330-009-1676-z},
  pages     = {1344 -- 1355},
  year      = {2010},
  abstract  = {Objective: As high-field cardiac MRI (CMR) becomes more widespread the propensity of ECG to interference from electromagnetic fields (EMF) and to magneto-hydrodynamic (MHD) effects increases and with it the motivation for a CMR triggering alternative. This study explores the suitability of acoustic cardiac triggering (ACT) for left ventricular (LV) function assessment in healthy subjects (n=14). Methods: Quantitative analysis of 2D CINE steady-state free precession (SSFP) images was conducted to compare ACT's performance with vector ECG (VCG). Endocardial border sharpness (EBS) was examined paralleled by quantitative LV function assessment. Results: Unlike VCG, ACT provided signal traces free of interference from EMF or MHD effects. In the case of correct Rwave recognition, VCG-triggered 2D CINE SSFP was immune to cardiac motion effects—even at 3.0 T. However, VCG-triggered 2D SSFP CINE imaging was prone to cardiac motion and EBS degradation if R-wave misregistration occurred. ACT-triggered acquisitions yielded LV parameters (end-diastolic volume (EDV), endsystolic volume (ESV), stroke volume (SV), ejection fraction (EF) and left ventricular mass (LVM)) comparable with those derived fromVCG-triggered acquisitions (1.5 T: ESVVCG=(56± 17) ml, EDVVCG=(151±32)ml, LVMVCG=(97±27) g, SVVCG=(94± 19)ml, EFVCG=(63±5)\% cf. ESVACT= (56±18) ml, EDVACT=(147±36) ml, LVMACT=(102±29) g, SVACT=(91± 22) ml, EFACT=(62±6)\%; 3.0 T: ESVVCG=(55±21) ml, EDVVCG=(151±32) ml, LVMVCG=(101±27) g, SVVCG=(96±15) ml, EFVCG=(65±7)\% cf. ESVACT=(54±20) ml, EDVACT=(146±35) ml, LVMACT= (101±30) g, SVACT=(92±17) ml, EFACT=(64±6)\%). Conclusions: ACT's intrinsic insensitivity to interference from electromagnetic fields renders},
  language  = {en}
}
@article{PetersonOsterPeterson2020,
  author    = {Peterson-Oster, Madeleine and Peterson, Leif Arne},
  title     = {Gewerbebau: Modellprojekt mit neuem elementiertem, freistehendem Fassadensystem},
  series = {Bauen mit Holz, Der Zimmermann},
  journal   = {Bauen mit Holz, Der Zimmermann},
  publisher = {Rudolf M{\"u}ller},
  address   = {K{\"o}ln},
  issn      = {0005-6545},
  year      = {2020},
  abstract  = {Die im Zuge einer Betriebs{\"u}bergabe anstehende Baumaßnahmen am eigenen B{\"u}ro- und Produktionsgeb{\"a}ude boten ideale Voraussetzung zur Anwendung einer raum­-kreierenden Außenhaut. Mit der elementierten, freistehenden Eichenholz-Fassade wurde ein bis dahin weitgehend funktionales Bauwerk substanzschonend und zugleich optisch ansprechender umgestaltet.},
  language  = {de}
}
@article{Finkenberger2021,
  author    = {Finkenberger, Isabel Maria},
  title     = {Wohnen als Produktionsgemeinschaftsaufgabe},
  series = {Jahrbuch f{\"u}r Christliche Sozialwissenschaften},
  journal   = {Jahrbuch f{\"u}r Christliche Sozialwissenschaften},
  number    = {62},
  publisher = {Aschendorff},
  address   = {M{\"u}nster},
  issn      = {0075-2584},
  doi       = {10.17879/jcsw-2021-3537},
  pages     = {31 -- 42},
  year      = {2021},
  abstract  = {Wohnen als neue soziale Frage ist mehr als die Produktion neuer Formen von Wohnen und deren architektonischer Gestalt, und auch mehr als nur die Umsetzung sich ver{\"a}ndernder, jedoch individuell formulierter Wohnw{\"u}nsche. Sie spannt sich auf zwischen gesellschafts- und nachhaltigkeitspolitischen, hardcore-kapitalistischen und globalen Rahmenbedingungen, Hardware und Software, Individuum und Gemeinwohl, Konsum und Mitgestaltung. Entscheidend sind die Akteure und die Art und Weise, wie und nach welchen Maßst{\"a}ben sie handeln. Entscheidend ist aber auch, Wohnen sowohl kontextuell wie auch programmatisch neu zu denken und dadurch zu neuen Mischungen, Nachbarschaften und Bewertungskriterien einer Projekt- und Stadtentwicklung zu kommen, die mehr als die Summe seiner Einzelteile wollen - ein gutes Leben f{\"u}r Alle abseits der Frage des Geldbeutels und der sozialen Zugeh{\"o}rigkeit.},
  language  = {de}
}
@article{Finkenberger2022,
  author    = {Finkenberger, Isabel Maria},
  title     = {Strukturwandel als transformative Wende},
  series = {disP: The Planning Review},
  volume    = {58},
  journal   = {disP: The Planning Review},
  number    = {3},
  publisher = {Taylor \& Francis},
  address   = {Abingdon},
  issn      = {0251-3625},
  doi       = {10.1080/02513625.2022.2158603},
  pages     = {86 -- 94},
  year      = {2022},
  language  = {de}
}
@article{FrauenrathHezelHeinrichsetal.2009,
  author    = {Frauenrath, Tobias and Hezel, Fabian and Heinrichs, Uwe and Kozerke, Sebastian and Utting, Jane and Kob, Malte and Butenweg, Christoph and Boesiger, Peter and Niendorf, Thoralf},
  title     = {Feasibility of Cardiac Gating Free of Interference With Electro-Magnetic Fields at 1.5 Tesla, 3.0 Tesla and 7.0 Tesla Using an MR-Stethoscope},
  series = {Investigative Radiology},
  volume    = {44},
  journal   = {Investigative Radiology},
  number    = {9},
  publisher = {Lippincott Williams \& Wilkins ; (via Ovid)},
  address   = {Philadelphia, Pa},
  issn      = {1536-0210 (online)},
  doi       = {10.1097/RLI.0b013e3181b4c15e},
  pages     = {539 -- 547},
  year      = {2009},
  language  = {en}
}
@article{HafidiElHatkaSchmitzetal.2024,
  author    = {Hafidi, Youssef and El Hatka, Hicham and Schmitz, Dominik and Krauss, Manuel and Pettrak, J{\"u}rgen and Biel, Markus and Ittobane, Najim},
  title     = {Sustainable soil additives for water and micronutrient supply: swelling and chelating properties of polyaspartic acid hydrogels utilizing newly developed crosslinkers},
  series = {Gels},
  volume    = {10},
  journal   = {Gels},
  number    = {3},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2310-2861},
  doi       = {10.3390/gels10030170},
  pages     = {Artikel 170},
  year      = {2024},
  abstract  = {Drought and water shortage are serious problems in many arid and semi-arid regions. This problem is getting worse and even continues in temperate climatic regions due to climate change. To address this problem, the use of biodegradable hydrogels is increasingly important for the application as water-retaining additives in soil. Furthermore, efficient (micro-)nutrient supply can be provided by the use of tailored hydrogels. Biodegradable polyaspartic acid (PASP) hydrogels with different available (1,6-hexamethylene diamine (HMD) and L-lysine (LYS)) and newly developed crosslinkers based on diesters of glycine (GLY) and (di-)ethylene glycol (DEG and EG, respectively) were synthesized and characterized using Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM) and regarding their swelling properties (kinetic, absorbency under load (AUL)) as well as biodegradability of PASP hydrogel. Copper (II) and zinc (II), respectively, were loaded as micronutrients in two different approaches: in situ with crosslinking and subsequent loading of prepared hydrogels. The results showed successful syntheses of di-glycine-ester-based crosslinkers. Hydrogels with good water-absorbing properties were formed. Moreover, the developed crosslinking agents in combination with the specific reaction conditions resulted in higher water absorbency with increased crosslinker content used in synthesis (10\% vs. 20\%). The prepared hydrogels are candidates for water-storing soil additives due to the biodegradability of PASP, which is shown in an exemple. The incorporation of Cu(II) and Zn(II) ions can provide these micronutrients for plant growth.},
  language  = {en}
}
@article{YoshinobuMiyamotoWagneretal.2024,
  author    = {Yoshinobu, Tatsuo and Miyamoto, Ko-ichiro and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Field-effect sensors combined with the scanned light pulse technique: from artificial olfactory images to chemical imaging technologies},
  series = {Chemosensors},
  volume    = {12},
  journal   = {Chemosensors},
  number    = {2},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2227-9040},
  doi       = {10.3390/chemosensors12020020},
  pages     = {Artikel 20},
  year      = {2024},
  abstract  = {The artificial olfactory image was proposed by Lundstr{\"o}m et al. in 1991 as a new strategy for an electronic nose system which generated a two-dimensional mapping to be interpreted as a fingerprint of the detected gas species. The potential distribution generated by the catalytic metals integrated into a semiconductor field-effect structure was read as a photocurrent signal generated by scanning light pulses. The impact of the proposed technology spread beyond gas sensing, inspiring the development of various imaging modalities based on the light addressing of field-effect structures to obtain spatial maps of pH distribution, ions, molecules, and impedance, and these modalities have been applied in both biological and non-biological systems. These light-addressing technologies have been further developed to realize the position control of a faradaic current on the electrode surface for localized electrochemical reactions and amperometric measurements, as well as the actuation of liquids in microfluidic devices.},
  language  = {en}
}
@article{BertzSchoeningMolinnusetal.2024,
  author    = {Bertz, Morten and Sch{\"o}ning, Michael Josef and Molinnus, Denise and Homma, Takayuki},
  title     = {Influence of temperature, light, and H₂O₂ concentration on microbial spore inactivation: in-situ Raman spectroscopy combined with optical trapping},
  series = {Physica status solidi (a) applications and materials science},
  journal   = {Physica status solidi (a) applications and materials science},
  number    = {Early View},
  publisher = {Wiley-VCH},
  address   = {Berlin},
  issn      = {1862-6319 (Online)},
  doi       = {10.1002/pssa.202300866},
  pages     = {8 Seiten},
  year      = {2024},
  abstract  = {To gain insight on chemical sterilization processes, the influence of temperature (up to 70 °C), intense green light, and hydrogen peroxide (H₂O₂) concentration (up to 30\% in aqueous solution) on microbial spore inactivation is evaluated by in-situ Raman spectroscopy with an optical trap. Bacillus atrophaeus is utilized as a model organism. Individual spores are isolated and their chemical makeup is monitored under dynamically changing conditions (temperature, light, and H₂O₂ concentration) to mimic industrially relevant process parameters for sterilization in the field of aseptic food processing. While isolated spores in water are highly stable, even at elevated temperatures of 70 °C, exposure to H₂O₂ leads to a loss of spore integrity characterized by the release of the key spore biomarker dipicolinic acid (DPA) in a concentration-dependent manner, which indicates damage to the inner membrane of the spore. Intensive light or heat, both of which accelerate the decomposition of H₂O₂ into reactive oxygen species (ROS), drastically shorten the spore lifetime, suggesting the formation of ROS as a rate-limiting step during sterilization. It is concluded that Raman spectroscopy can deliver mechanistic insight into the mode of action of H₂O₂-based sterilization and reveal the individual contributions of different sterilization methods acting in tandem.},
  language  = {en}
}
@article{PogorelovaRogachevAkimbekovetal.2024,
  author    = {Pogorelova, Natalia and Rogachev, Evgeniy and Akimbekov, Nuraly S. and Digel, Ilya},
  title     = {Effect of dehydration method on the micro- and nanomorphological properties of bacterial cellulose produced by Medusomyces gisevii on different substrates},
  series = {Journal of materials science},
  volume    = {2024},
  journal   = {Journal of materials science},
  publisher = {Springer Science + Business Media},
  address   = {Dordrecht},
  issn      = {1573-4803 (Online)},
  doi       = {10.1007/s10853-024-09596-3},
  pages     = {13 Seiten},
  year      = {2024},
  abstract  = {Many important properties of bacterial cellulose (BC), such as moisture absorption capacity, elasticity and tensile strength, largely depend on its structure. This paper presents a study on the effect of the drying method on BC films produced by Medusomyces gisevii using two different procedures: room temperature drying (RT, (24 ± 2 °C, humidity 65 ± 1\%, dried until a constant weight was reached) and freeze-drying (FD, treated at - 75 °C for 48 h). BC was synthesized using one of two different carbon sources—either glucose or sucrose. Structural differences in the obtained BC films were evaluated using atomic force microscopy (AFM), scanning electron microscopy (SEM), and X-ray diffraction. Macroscopically, the RT samples appeared semi-transparent and smooth, whereas the FD group exhibited an opaque white color and sponge-like structure. SEM examination showed denser packing of fibrils in FD samples while RT-samples displayed smaller average fiber diameter, lower surface roughness and less porosity. AFM confirmed the SEM observations and showed that the FD material exhibited a more branched structure and a higher surface roughness. The samples cultivated in a glucose-containing nutrient medium, generally displayed a straight and ordered shape of fibrils compared to the sucrose-derived BC, characterized by a rougher and wavier structure. The BC films dried under different conditions showed distinctly different crystallinity degrees, whereas the carbon source in the culture medium was found to have a relatively small effect on the BC crystallinity.},
  language  = {en}
}
@article{Finkenberger2022,
  author    = {Finkenberger, Isabel Maria},
  title     = {Transformatives Forschen, Lehren und Handeln im Rheinischen Braunkohlerevier},
  series = {Forum Wohnen und Stadtentwicklung},
  volume    = {2022},
  journal   = {Forum Wohnen und Stadtentwicklung},
  number    = {2},
  publisher = {vhw},
  address   = {Berlin},
  issn      = {1439-7242},
  pages     = {69 -- 72},
  year      = {2022},
  abstract  = {Die Institution Hochschule hat das Potenzial, {\"u}ber transformatives Forschen und Lehren und den entsprechenden Wissenstransfer in den lokalen Kontext strategisch-verl{\"a}ssliche Partnerin der Großen Transformation zur Nachhaltigkeit zu werden und bei der Ausbildung von Pionierinnen und Pionieren des Wandels mitzuwirken. Der Lehr- und Forschungsschwerpunkt „Zukunftsf{\"a}hige Transformation" am Fachbereich Architektur der FH Aachen widmet sich seit 2020 dem Tagebauumfeld Hambach im Rheinischen Revier, um dort angewandt und in Kooperation neue Narrative, innovative Prozesse, ortsbezogene Konzepte und strategische Projekte zu entwickeln und umzusetzen.},
  language  = {de}
}
@article{FinkenbergerSchlaich2014,
  author    = {Finkenberger, Isabel Maria and Schlaich, Christoph},
  title     = {Mehr als Wohnen. Vom Zusammenleben in integrierten Nachbarschaften},
  series = {APuZ - Aus Politik und Zeitgeschichte},
  volume    = {2014},
  journal   = {APuZ - Aus Politik und Zeitgeschichte},
  number    = {20-21},
  publisher = {Bundeszentrale f{\"u}r politische Bildung - bpb},
  address   = {Bonn},
  issn      = {2194-3621},
  pages     = {46 -- 52},
  year      = {2014},
  abstract  = {Neue D{\"o}rfer braucht das Land! D{\"o}rfer in der Stadt und D{\"o}rfer auf dem Land (…). Die Planung und Gestaltung nachhaltiger Raumsysteme, die durch ein neues Verst{\"a}ndnis des gemeinschaftlichen Besitzes (und dessen Nutzung) ressourcenfressende Individualisierungstendenzen unserer Gesellschaft {\"u}berwinden, aber zugleich gr{\"o}ßtm{\"o}glichen Freiraum f{\"u}r eine individuelle Pers{\"o}nlichkeitsentfaltung zur Verf{\"u}gung stellen." Dieses Zitat der Hamburger Initiative "Wir sind Dorf" beschreibt eine aktuelle Diskussion in unserer Gesellschaft, die sowohl in der Forschung und forschungsgeleiteten Initiativen, in Politik und Planung als auch in der B{\"u}rger-schaft stattfindet. Sie wird nicht nur auf wissenschaftlichen Veranstaltungen gef{\"u}hrt, sondern auch in konkreten Projekten f{\"u}r integrative Lebenswelten, die Fragestellungen von Ern{\"a}hrung und Energieversorgung, von Arbeit und {\"O}konomie, aber auch eines neuen r{\"a}umlichen und sozialen Miteinanders einbeziehen. Anders als bei den weit verbreiteten Baugruppen geht es nicht ausschließlich um die Schaffung von Wohnraum. Die Nachbarschaftsidee verbindet das Bed{\"u}rfnis nach gemeinschaftlichem Wohnen und Wirtschaften mit einer neuen Werteorientierung, die auf pers{\"o}nlicher Verantwortungs{\"u}bernahme beruht.},
  language  = {de}
}
@article{Finkenberger2014,
  author    = {Finkenberger, Isabel Maria},
  title     = {Vox populi. (Transformations-)potenziale nachkriegsmoderner Freiraumressourcen},
  series = {Stadt+Gr{\"u}n},
  volume    = {2014},
  journal   = {Stadt+Gr{\"u}n},
  number    = {1},
  publisher = {Patzer},
  address   = {Berlin},
  issn      = {0948-9770},
  pages     = {31 -- 35},
  year      = {2014},
  abstract  = {Heute wie damals werden die großz{\"u}gigen und offenen Siedlungsstrukturen der ersten Nachkriegsjahrzehnte mit ihrem hohen Anteil an "Gr{\"u}n" vielfach gesch{\"a}tzt und als solche nicht grundlegend hinterfragt. "Gr{\"u}n" verheißt im Allgemeinen Licht, Luft und Sonne, Freizeit und Erholung und gilt als etwas W{\"u}nschenswertes im st{\"a}dtischen Kontext. Unbeachtet bleibt, dass dem Begriff "Gr{\"u}n" zun{\"a}chst keine Eigenschaften oder Qualit{\"a}ten zugewiesen sind - er sagt noch lange nichts {\"u}ber dessen r{\"a}umliche Qualit{\"a}t, dessen Nutzbarkeit, Erreichbarkeit und Zug{\"a}nglichkeit aus. Abstandsgr{\"u}n und Straßenbegleitgr{\"u}n ist eben auch "Gr{\"u}n". Neben einer quantitativen Argumentation, welche {\"o}kologischen Aspekte wie Biotopvernetzung, Stadt- und Mikroklima ber{\"u}cksichtigt, sollten wir verst{\"a}rkt qualitativ denken und damit die Grundlage f{\"u}r einen erweiterten und wesentlich differenzierteren Diskurs {\"u}ber urbane Freir{\"a}ume ebnen.},
  language  = {de}
}
@article{HoffstadtNikolauszKrafftetal.2024,
  author    = {Hoffstadt, Kevin and Nikolausz, Marcell and Krafft, Simone and Bonatelli, Maria and Kumar, Vivekanantha and Harms, Hauke and Kuperjans, Isabel},
  title     = {Optimization of the ex situ biomethanation of hydrogen and carbon dioxide in a novel meandering plug flow reactor: start-up phase and flexible operation},
  series = {Bioengineering},
  volume    = {11},
  journal   = {Bioengineering},
  number    = {2},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2306-5354},
  doi       = {10.3390/bioengineering11020165},
  pages     = {18 Seiten},
  year      = {2024},
  language  = {en}
}
@article{KarschuckPoghossianSeretal.2024,
  author    = {Karschuck, Tobias and Poghossian, Arshak and Ser, Joey and Tsokolakyan, Astghik and Achtsnicht, Stefan and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Capacitive model of enzyme-modified field-effect biosensors: Impact of enzyme coverage},
  series = {Sensors and Actuators B: Chemical},
  volume    = {408},
  journal   = {Sensors and Actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005 (Print)},
  doi       = {10.1016/j.snb.2024.135530},
  pages     = {12 Seiten},
  year      = {2024},
  abstract  = {Electrolyte-insulator-semiconductor capacitors (EISCAP) belong to field-effect sensors having an attractive transducer architecture for constructing various biochemical sensors. In this study, a capacitive model of enzyme-modified EISCAPs has been developed and the impact of the surface coverage of immobilized enzymes on its capacitance-voltage and constant-capacitance characteristics was studied theoretically and experimentally. The used multicell arrangement enables a multiplexed electrochemical characterization of up to sixteen EISCAPs. Different enzyme coverages have been achieved by means of parallel electrical connection of bare and enzyme-covered single EISCAPs in diverse combinations. As predicted by the model, with increasing the enzyme coverage, both the shift of capacitance-voltage curves and the amplitude of the constant-capacitance signal increase, resulting in an enhancement of analyte sensitivity of the EISCAP biosensor. In addition, the capability of the multicell arrangement with multi-enzyme covered EISCAPs for sequentially detecting multianalytes (penicillin and urea) utilizing the enzymes penicillinase and urease has been experimentally demonstrated and discussed.},
  language  = {en}
}
@article{BornheimGriegerBlanecketal.2024,
  author    = {Bornheim, Tobias and Grieger, Niklas and Blaneck, Patrick Gustav and Bialonski, Stephan},
  title     = {Speaker Attribution in German Parliamentary Debates with QLoRA-adapted Large Language Models},
  series = {Journal for language technology and computational linguistics : JLCL},
  volume    = {37},
  journal   = {Journal for language technology and computational linguistics : JLCL},
  number    = {1},
  publisher = {Gesellschaft f{\"u}r Sprachtechnologie und Computerlinguistik},
  address   = {Regensburg},
  issn      = {2190-6858},
  doi       = {10.21248/jlcl.37.2024.244},
  pages     = {13 Seiten},
  year      = {2024},
  abstract  = {The growing body of political texts opens up new opportunities for rich insights into political dynamics and ideologies but also increases the workload for manual analysis. Automated speaker attribution, which detects who said what to whom in a speech event and is closely related to semantic role labeling, is an important processing step for computational text analysis. We study the potential of the large language model family Llama 2 to automate speaker attribution in German parliamentary debates from 2017-2021. We fine-tune Llama 2 with QLoRA, an efficient training strategy, and observe our approach to achieve competitive performance in the GermEval 2023 Shared Task On Speaker Attribution in German News Articles and Parliamentary Debates. Our results shed light on the capabilities of large language models in automating speaker attribution, revealing a promising avenue for computational analysis of political discourse and the development of semantic role labeling systems.},
  language  = {en}
}
@article{BaumgartnerFidlerWethetal.2008,
  author    = {Baumgartner, Werner and Fidler, Florian and Weth, Agnes and Habbecke, Martin and Jakob, Peter and Butenweg, Christoph and B{\"o}hme, Wolfgang},
  title     = {Investigating the locomotion of the sandfish in desert sand using NMR-Imaging},
  series = {PLOS ONE},
  volume    = {3},
  journal   = {PLOS ONE},
  number    = {10},
  publisher = {Plos},
  address   = {San Francisco, California, US},
  issn      = {1932-6203},
  doi       = {10.1371/journal.pone.0003309},
  pages     = {e3309},
  year      = {2008},
  abstract  = {The sandfish (Scincus scincus) is a lizard having the remarkable ability to move through desert sand for significant distances. It is well adapted to living in loose sand by virtue of a combination of morphological and behavioural specializations. We investigated the bodyform of the sandfish using 3D-laserscanning and explored its locomotion in loose desert sand using fast nuclear magnetic resonance (NMR) imaging. The sandfish exhibits an in-plane meandering motion with a frequency of about 3 Hz and an amplitude of about half its body length accompanied by swimming-like (or trotting) movements of its limbs. No torsion of the body was observed, a movement required for a digging-behaviour. Simple calculations based on the Janssen model for granular material related to our findings on bodyform and locomotor behaviour render a local decompaction of the sand surrounding the moving sandfish very likely. Thus the sand locally behaves as a viscous fluid and not as a solid material. In this fluidised sand the sandfish is able to "swim" using its limbs.},
  language  = {en}
}
@article{SchoenrockMuckeltHastermannetal.2024,
  author    = {Schoenrock, Britt and Muckelt, Paul E. and Hastermann, Maria and Albracht, Kirsten and MacGregor, Robert and Martin, David and Gunga, Hans-Christian and Salanova, Michele and Stokes, Maria J. and Warner, Martin B. and Blottner, Dieter},
  title     = {Muscle stiffness indicating mission crew health in space},
  series = {Scientific Reports},
  volume    = {14},
  journal   = {Scientific Reports},
  number    = {Article number: 4196},
  publisher = {Springer Nature},
  address   = {London},
  issn      = {2045-2322},
  doi       = {10.1038/s41598-024-54759-6},
  pages     = {13 Seiten},
  year      = {2024},
  abstract  = {Muscle function is compromised by gravitational unloading in space affecting overall musculoskeletal health. Astronauts perform daily exercise programmes to mitigate these effects but knowing which muscles to target would optimise effectiveness. Accurate inflight assessment to inform exercise programmes is critical due to lack of technologies suitable for spaceflight. Changes in mechanical properties indicate muscle health status and can be measured rapidly and non-invasively using novel technology. A hand-held MyotonPRO device enabled monitoring of muscle health for the first time in spaceflight (> 180 days). Greater/maintained stiffness indicated countermeasures were effective. Tissue stiffness was preserved in the majority of muscles (neck, shoulder, back, thigh) but Tibialis Anterior (foot lever muscle) stiffness decreased inflight vs. preflight (p < 0.0001; mean difference 149 N/m) in all 12 crewmembers. The calf muscles showed opposing effects, Gastrocnemius increasing in stiffness Soleus decreasing. Selective stiffness decrements indicate lack of preservation despite daily inflight countermeasures. This calls for more targeted exercises for lower leg muscles with vital roles as ankle joint stabilizers and in gait. Muscle stiffness is a digital biomarker for risk monitoring during future planetary explorations (Moon, Mars), for healthcare management in challenging environments or clinical disorders in people on Earth, to enable effective tailored exercise programmes.},
  language  = {en}
}
@article{KahmannRauschPluemeretal.2022,
  author    = {Kahmann, Stephanie L. and Rausch, Valentin and Pl{\"u}mer, Jonathan and M{\"u}ller, Lars P. and Pieper, Martin and Wegmann, Kilian},
  title     = {The automized fracture edge detection and generation of three-dimensional fracture probability heat maps},
  series = {Medical Engineering \& Physics},
  volume    = {2022},
  journal   = {Medical Engineering \& Physics},
  number    = {110},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1350-4533},
  pages     = {7 Seiten},
  year      = {2022},
  abstract  = {With proven impact of statistical fracture analysis on fracture classifications, it is desirable to minimize the manual work and to maximize repeatability of this approach. We address this with an algorithm that reduces the manual effort to segmentation, fragment identification and reduction. The fracture edge detection and heat map generation are performed automatically. With the same input, the algorithm always delivers the same output. The tool transforms one intact template consecutively onto each fractured specimen by linear least square optimization, detects the fragment edges in the template and then superimposes them to generate a fracture probability heat map. We hypothesized that the algorithm runs faster than the manual evaluation and with low (< 5 mm) deviation. We tested the hypothesis in 10 fractured proximal humeri and found that it performs with good accuracy (2.5 mm ± 2.4 mm averaged Euclidean distance) and speed (23 times faster). When applied to a distal humerus, a tibia plateau, and a scaphoid fracture, the run times were low (1-2 min), and the detected edges correct by visual judgement. In the geometrically complex acetabulum, at a run time of 78 min some outliers were considered acceptable. An automatically generated fracture probability heat map based on 50 proximal humerus fractures matches the areas of high risk of fracture reported in medical literature. Such automation of the fracture analysis method is advantageous and could be extended to reduce the manual effort even further.},
  language  = {en}
}
@article{EngelmannSimsekShalabyetal.2024,
  author    = {Engelmann, Ulrich M. and Simsek, Beril and Shalaby, Ahmed and Krause, Hans-Joachim},
  title     = {Key contributors to signal generation in frequency mixing magnetic detection (FMMD): an in silico study},
  series = {Sensors},
  volume    = {24},
  journal   = {Sensors},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s24061945},
  pages     = {Artikel 1945},
  year      = {2024},
  abstract  = {Frequency mixing magnetic detection (FMMD) is a sensitive and selective technique to detect magnetic nanoparticles (MNPs) serving as probes for binding biological targets. Its principle relies on the nonlinear magnetic relaxation dynamics of a particle ensemble interacting with a dual frequency external magnetic field. In order to increase its sensitivity, lower its limit of detection and overall improve its applicability in biosensing, matching combinations of external field parameters and internal particle properties are being sought to advance FMMD. In this study, we systematically probe the aforementioned interaction with coupled N{\´e}el-Brownian dynamic relaxation simulations to examine how key MNP properties as well as applied field parameters affect the frequency mixing signal generation. It is found that the core size of MNPs dominates their nonlinear magnetic response, with the strongest contributions from the largest particles. The drive field amplitude dominates the shape of the field-dependent response, whereas effective anisotropy and hydrodynamic size of the particles only weakly influence the signal generation in FMMD. For tailoring the MNP properties and parameters of the setup towards optimal FMMD signal generation, our findings suggest choosing large particles of core sizes dc > 25 nm nm with narrow size distributions (σ < 0.1) to minimize the required drive field amplitude. This allows potential improvements of FMMD as a stand-alone application, as well as advances in magnetic particle imaging, hyperthermia and magnetic immunoassays.},
  language  = {en}
}
@article{ZhenLiangStaatetal.2024,
  author    = {Zhen, Manghao and Liang, Yunpei and Staat, Manfred and Li, Quanqui and Li, Jianbo},
  title     = {Discontinuous fracture behaviors and constitutive model of sandstone specimens containing non-parallel prefabricated fissures under uniaxial compression},
  series = {Theoretical and Applied Fracture Mechanics},
  volume    = {131},
  journal   = {Theoretical and Applied Fracture Mechanics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0167-8442},
  doi       = {10.1016/j.tafmec.2024.104373},
  pages     = {Artikel 104373},
  year      = {2024},
  abstract  = {The deformation and damage laws of non-homogeneous irregular structural planes in rocks are the basis for studying the stability of rock engineering. To investigate the damage characteristics of rock containing non-parallel fissures, uniaxial compression tests and numerical simulations were conducted on sandstone specimens containing three non-parallel fissures inclined at 0°, 45° and 90° in this study. The characteristics of crack initiation and crack evolution of fissures with different inclinations were analyzed. A constitutive model for the discontinuous fractures of fissured sandstone was proposed. The results show that the fracture behaviors of fissured sandstone specimens are discontinuous. The stress-strain curves are non-smooth and can be divided into nonlinear crack closure stage, linear elastic stage, plastic stage and brittle failure stage, of which the plastic stage contains discontinuous stress drops. During the uniaxial compression test, the middle or ends of 0° fissures were the first to crack compared to 45° and 90° fissures. The end with small distance between 0° and 45° fissures cracked first, and the end with large distance cracked later. After the final failure, 0° fissures in all specimens were fractured, while 45° and 90° fissures were not necessarily fractured. Numerical simulation results show that the concentration of compressive stress at the tips of 0°, 45° and 90° fissures, as well as the concentration of tensile stress on both sides, decreased with the increase of the inclination angle. A constitutive model for the discontinuous fractures of fissured sandstone specimens was derived by combining the logistic model and damage mechanic theory. This model can well describe the discontinuous drops of stress and agrees well with the whole processes of the stress-strain curves of the fissured sandstone specimens.},
  language  = {en}
}
@article{SchwagerFleschSchwarzboezletal.2022,
  author    = {Schwager, Christian and Flesch, Robert and Schwarzb{\"o}zl, Peter and Herrmann, Ulf and Teixeira Boura, Cristiano Jos{\´e}},
  title     = {Advanced two phase flow model for transient molten salt receiver system simulation},
  series = {Solar Energy},
  volume    = {232},
  journal   = {Solar Energy},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0038-092X (print)},
  doi       = {10.1016/j.solener.2021.12.065},
  pages     = {362 -- 375},
  year      = {2022},
  abstract  = {In order to realistically predict and optimize the actual performance of a concentrating solar power (CSP) plant sophisticated simulation models and methods are required. This paper presents a detailed dynamic simulation model for a Molten Salt Solar Tower (MST) system, which is capable of simulating transient operation including detailed startup and shutdown procedures including drainage and refill. For appropriate representation of the transient behavior of the receiver as well as replication of local bulk and surface temperatures a discretized receiver model based on a novel homogeneous two-phase (2P) flow modelling approach is implemented in Modelica Dymola®. This allows for reasonable representation of the very different hydraulic and thermal properties of molten salt versus air as well as the transition between both. This dynamic 2P receiver model is embedded in a comprehensive one-dimensional model of a commercial scale MST system and coupled with a transient receiver flux density distribution from raytracing based heliostat field simulation. This enables for detailed process prediction with reasonable computational effort, while providing data such as local salt film and wall temperatures, realistic control behavior as well as net performance of the overall system. Besides a model description, this paper presents some results of a validation as well as the simulation of a complete startup procedure. Finally, a study on numerical simulation performance and grid dependencies is presented and discussed.},
  language  = {en}
}
@article{PieronekKleefeld2024,
  author    = {Pieronek, Lukas and Kleefeld, Andreas},
  title     = {On trajectories of complex-valued interior transmission eigenvalues},
  series = {Inverse problems and imaging : IPI},
  volume    = {18},
  journal   = {Inverse problems and imaging : IPI},
  number    = {2},
  publisher = {AIMS},
  address   = {Springfield, Mo},
  issn      = {1930-8337 (Print)},
  doi       = {10.3934/ipi.2023041},
  pages     = {480 -- 516},
  year      = {2024},
  abstract  = {This paper investigates the interior transmission problem for homogeneous media via eigenvalue trajectories parameterized by the magnitude of the refractive index. In the case that the scatterer is the unit disk, we prove that there is a one-to-one correspondence between complex-valued interior transmission eigenvalue trajectories and Dirichlet eigenvalues of the Laplacian which turn out to be exactly the trajectorial limit points as the refractive index tends to infinity. For general simply-connected scatterers in two or three dimensions, a corresponding relation is still open, but further theoretical results and numerical studies indicate a similar connection.},
  language  = {en}
}
@article{SchoppRohrbachLangeretal.2024,
  author    = {Schopp, Christoph and Rohrbach, Felix and Langer, Luc and Heuermann, Holger},
  title     = {Detection of welding wire length by active S11 measurement},
  series = {IEEE Transactions on Plasma Science},
  journal   = {IEEE Transactions on Plasma Science},
  number    = {Early Access},
  publisher = {IEEE},
  issn      = {0093-3813 (Print)},
  doi       = {10.1109/TPS.2024.3356659},
  pages     = {1 -- 6},
  year      = {2024},
  abstract  = {A novel method to determine the extruded length of a metallic wire for a directed energy deposition (DED) process using a microwave (MW) plasma jet with a straight-through wire feed is presented. The method is based on the relative comparison of the measured frequency response obtained by the large-signal scattering parameter (Hot-S) technique. In the practical working range, repeatability of less than 6\% for a nonactive plasma and 9\% for the active plasma state is found. Measurements are conducted with a focus on a simple solution to decrease the processing time and reduce the integration time of the process into the existing hardware. It is shown that monitoring a single frequency for magnitude and phase changes is sufficient to achieve good accuracy. A combination of different measurement values to determine the length is possible. The applicability to different diameter of the same material is shown as well as a contact detection of the wire and metallic substrate.},
  language  = {en}
}
@article{BoehnischBraunMuscarelloetal.2024,
  author    = {B{\"o}hnisch, Nils and Braun, Carsten and Muscarello, Vincenzo and Marzocca, Pier},
  title     = {About the wing and whirl flutter of a slender wing-propeller system},
  series = {Journal of Aircraft},
  journal   = {Journal of Aircraft},
  publisher = {AIAA},
  address   = {Reston, Va.},
  issn      = {1533-3868},
  doi       = {10.2514/1.C037542},
  pages     = {1 -- 14},
  year      = {2024},
  abstract  = {Next-generation aircraft designs often incorporate multiple large propellers attached along the wingspan (distributed electric propulsion), leading to highly flexible dynamic systems that can exhibit aeroelastic instabilities. This paper introduces a validated methodology to investigate the aeroelastic instabilities of wing-propeller systems and to understand the dynamic mechanism leading to wing and whirl flutter and transition from one to the other. Factors such as nacelle positions along the wing span and chord and its propulsion system mounting stiffness are considered. Additionally, preliminary design guidelines are proposed for flutter-free wing-propeller systems applicable to novel aircraft designs. The study demonstrates how the critical speed of the wing-propeller systems is influenced by the mounting stiffness and propeller position. Weak mounting stiffnesses result in whirl flutter, while hard mounting stiffnesses lead to wing flutter. For the latter, the position of the propeller along the wing span may change the wing mode shapes and thus the flutter mechanism. Propeller positions closer to the wing tip enhance stability, but pusher configurations are more critical due to the mass distribution behind the elastic axis.},
  language  = {en}
}
@article{TurdumamatovBeldaHeuermann2024,
  author    = {Turdumamatov, Samat and Belda, Aljoscha and Heuermann, Holger},
  title     = {Shaping a decoupled atmospheric pressure microwave plasma with antenna structures, Maxwell's equations, and boundary conditions},
  series = {IEEE Transactions on Plasma Science},
  journal   = {IEEE Transactions on Plasma Science},
  number    = {Early Access},
  publisher = {IEEE},
  issn      = {0093-3813 (Print)},
  doi       = {10.1109/TPS.2024.3383589},
  pages     = {1 -- 9},
  year      = {2024},
  abstract  = {This article addresses the need for an innovative technique in plasma shaping, utilizing antenna structures, Maxwell's laws, and boundary conditions within a shielded environment. The motivation lies in exploring a novel approach to efficiently generate high-energy density plasma with potential applications across various fields. Implemented in an E01 circular cavity resonator, the proposed method involves the use of an impedance and field matching device with a coaxial connector and a specially optimized monopole antenna. This setup feeds a low-loss cavity resonator, resulting in a high-energy density air plasma with a surface temperature exceeding 3500 o C, achieved with a minimal power input of 80 W. The argon plasma, resembling the shape of a simple monopole antenna with modeled complex dielectric values, offers a more energy-efficient alternative compared to traditional, power-intensive plasma shaping methods. Simulations using a commercial electromagnetic (EM) solver validate the design's effectiveness, while experimental validation underscores the method's feasibility and practical implementation. Analyzing various parameters in an argon atmosphere, including hot S -parameters and plasma beam images, the results demonstrate the successful application of this technique, suggesting its potential in coating, furnace technology, fusion, and spectroscopy applications.},
  language  = {en}
}
@article{StiemerThomaBraun2023,
  author    = {Stiemer, Luc Nicolas and Thoma, Andreas and Braun, Carsten},
  title     = {MBT3D: Deep learning based multi-object tracker for bumblebee 3D flight path estimation},
  series = {PLoS ONE},
  volume    = {18},
  journal   = {PLoS ONE},
  number    = {9},
  publisher = {PLOS},
  address   = {San Fancisco},
  issn      = {1932-6203},
  doi       = {10.1371/journal.pone.0291415},
  pages     = {e0291415},
  year      = {2023},
  abstract  = {This work presents the Multi-Bees-Tracker (MBT3D) algorithm, a Python framework implementing a deep association tracker for Tracking-By-Detection, to address the challenging task of tracking flight paths of bumblebees in a social group. While tracking algorithms for bumblebees exist, they often come with intensive restrictions, such as the need for sufficient lighting, high contrast between the animal and background, absence of occlusion, significant user input, etc. Tracking flight paths of bumblebees in a social group is challenging. They suddenly adjust movements and change their appearance during different wing beat states while exhibiting significant similarities in their individual appearance. The MBT3D tracker, developed in this research, is an adaptation of an existing ant tracking algorithm for bumblebee tracking. It incorporates an offline trained appearance descriptor along with a Kalman Filter for appearance and motion matching. Different detector architectures for upstream detections (You Only Look Once (YOLOv5), Faster Region Proposal Convolutional Neural Network (Faster R-CNN), and RetinaNet) are investigated in a comparative study to optimize performance. The detection models were trained on a dataset containing 11359 labeled bumblebee images. YOLOv5 reaches an Average Precision of AP = 53, 8\%, Faster R-CNN achieves AP = 45, 3\% and RetinaNet AP = 38, 4\% on the bumblebee validation dataset, which consists of 1323 labeled bumblebee images. The tracker's appearance model is trained on 144 samples. The tracker (with Faster R-CNN detections) reaches a Multiple Object Tracking Accuracy MOTA = 93, 5\% and a Multiple Object Tracking Precision MOTP = 75, 6\% on a validation dataset containing 2000 images, competing with state-of-the-art computer vision methods. The framework allows reliable tracking of different bumblebees in the same video stream with rarely occurring identity switches (IDS). MBT3D has much lower IDS than other commonly used algorithms, with one of the lowest false positive rates, competing with state-of-the-art animal tracking algorithms. The developed framework reconstructs the 3-dimensional (3D) flight paths of the bumblebees by triangulation. It also handles and compares two alternative stereo camera pairs if desired.},
  language  = {en}
}
@article{BiewendtBlaschkeBoehnert2021,
  author    = {Biewendt, Marcel and Blaschke, Florian and B{\"o}hnert, Arno},
  title     = {A review of contemporary challenges in business culture},
  series = {International Journal of Applied Research in Business and Management},
  volume    = {2},
  journal   = {International Journal of Applied Research in Business and Management},
  number    = {1},
  publisher = {Wohllebe \& Ross Publishing},
  address   = {Hamburg},
  issn      = {2700-8983},
  doi       = {10.51137/ijarbm.2021.2.1.1},
  pages     = {1 -- 12},
  year      = {2021},
  abstract  = {The following article deals with the basic principles of intercultural management and possible improvements in terms of cultural, ethnic and gender diversification. The results are exemplarily applied to a bank located in Germany. The aim of this paper is to find out to what extent intercultural management could improve the productivity of Relatos-Bank in dealing with foreign employees or employees with a different cultural background. To achieve this goal, the authors con-duct a literature research. The main sources of information are books, journal articles and internet sources. It becomes clear that especially the different perceptions of different generations have a potential for conflict, which can be counteracted by applying presented scientific models. Equalizing the salaries of female and male employees and equalizing the rights and distribution of power could also be the key to becoming an open-minded, dynamic and fair organization that is pre-pared for the rapidly changing environment in which it operates.},
  language  = {en}
}
@article{Biewendt2020,
  author    = {Biewendt, Marcel},
  title     = {Sustainable development: A quantitative analysis regarding the impact of resource rents on state welfare from 2002 to 2017},
  series = {SocioEconomic Challenges},
  volume    = {4},
  journal   = {SocioEconomic Challenges},
  number    = {4},
  publisher = {ARMG Publishing},
  address   = {Sumy},
  issn      = {2520-6214},
  doi       = {10.21272/sec.4(4).119-131.2020},
  pages     = {119 -- 131},
  year      = {2020},
  abstract  = {This paper uses a quantitative analysis to examine the interdependence and impact of resource rents on socio-economic development from 2002 to 2017. Nigeria and Norway have been chosen as reference countries due to their abundance of natural resources by similar economic performance, while the ranking in the Human Development Index differs dramatically. As the Human Development Index provides insight into a country's cultural and socio-economic characteristics and development in addition to economic indicators, it allows a comparison of the two countries. The hypothesis presented and discussed in this paper was researched before. A qualitative research approach was used in the author's master's thesis "The Human Development Index (HDI) as a Reflection of Resource Abundance (using Nigeria and Norway as a case study)" in 2018. The management of scarce resources is an important aspect in the development of modern countries and those on the threshold of becoming industrialised nations. The effects of a mistaken resource management are not only of a purely economic nature but also of a social and socio-economic nature. In order to present a partial aspect of these dependencies and influences this paper uses a quantitative analysis to examine the interdependence and impact of resource rents on socio-economic development from 2002 to 2017. Nigeria and Norway have been chosen as reference countries due to their abundance of natural resources by similar economic performance, while the ranking in the Human Development Index differs significantly. As the Human Development Index provides insight into a country's cultural and socio-economic characteristics and development in addition to economic indicators, it allows a comparison of the two countries. This paper found out in a holistic perspective that (not or poorly managed) resource wealth in itself has a negative impact on socio-economic development and significantly reduces the productivity of the citizens of a state. This is expressed in particular for the years 2002 till 2017 in a negative correlation of GDP per capita and HDI value with the share respectively the size of resources in the GDP of a country.},
  language  = {en}
}
@article{AdelsMonakhova2024,
  author    = {Adels, Klaudia and Monakhova, Yulia},
  title     = {Low-field NMR spectroscopic study of e-cigarettes: Is determination of only nicotine and organic carrier solvents possible?},
  series = {Microchemical Journal},
  volume    = {203},
  journal   = {Microchemical Journal},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1095-9149},
  doi       = {10.1016/j.microc.2024.110859},
  pages     = {9 Seiten},
  year      = {2024},
  abstract  = {Electronic cigarettes (e-cigarettes) have become popular worldwide with the market growing exponentially in some countries. The absence of product standards and safety regulations requires urgent development of analytical methodologies for the holistic control of the growing diversity of such products. An approach based on low-field nuclear magnetic resonance (LF-NMR) at 80 MHz is presented for the simultaneous determination of key parameters: carrier solvents (vegetable glycerine (VG), propylene glycol (PG) and water), total nicotine as well as free-base nicotine fraction. Moreover, qualitative and quantitative determination of fourteen weak organic acids deliberately added to enhance sensory characteristics of e-cigarettes was possible. In most cases these parameters can be rapidly and conveniently determined without using any sample manipulation such as dilution, extraction or derivatization steps. The method was applied for 37 authentic e-cigarettes samples. In particular, eight different organic acids with the content up to 56 mg/mL were detected. Due to its simplicity, the method can be used in routine regulatory control as well as to study release behaviour of nicotine and other e-cigarettes constituents in different products.},
  language  = {en}
}
@article{MoehrenBergmannJanseretal.2024,
  author    = {M{\"o}hren, Felix and Bergmann, Ole and Janser, Frank and Braun, Carsten},
  title     = {Assessment of structural mechanical effects related to torsional deformations of propellers},
  series = {CEAS Aeronautical Journal},
  journal   = {CEAS Aeronautical Journal},
  publisher = {Springer},
  address   = {Wien},
  issn      = {1869-5590 (eISSN)},
  doi       = {10.1007/s13272-024-00737-7},
  pages     = {22 Seiten},
  year      = {2024},
  abstract  = {Lifting propellers are of increasing interest for Advanced Air Mobility. All propellers and rotors are initially twisted beams, showing significant extension-twist coupling and centrifugal twisting. Torsional deformations severely impact aerodynamic performance. This paper presents a novel approach to assess different reasons for torsional deformations. A reduced-order model runs large parameter sweeps with algebraic formulations and numerical solution procedures. Generic beams represent three different propeller types for General Aviation, Commercial Aviation, and Advanced Air Mobility. Simulations include solid and hollow cross-sections made of aluminum, steel, and carbon fiber-reinforced polymer. The investigation shows that centrifugal twisting moments depend on both the elastic and initial twist. The determination of the centrifugal twisting moment solely based on the initial twist suffers from errors exceeding 5\% in some cases. The nonlinear parts of the torsional rigidity do not significantly impact the overall torsional rigidity for the investigated propeller types. The extension-twist coupling related to the initial and elastic twist in combination with tension forces significantly impacts the net cross-sectional torsional loads. While the increase in torsional stiffness due to initial twist contributes to the overall stiffness for General and Commercial Aviation propellers, its contribution to the lift propeller's stiffness is limited. The paper closes with the presentation of approximations for each effect identified as significant. Numerical evaluations are necessary to determine each effect for inhomogeneous cross-sections made of anisotropic material.},
  language  = {en}
}
@article{ThomaGardiFisheretal.2024,
  author    = {Thoma, Andreas and Gardi, Alessandro and Fisher, Alex and Braun, Carsten},
  title     = {Improving local path planning for UAV flight in challenging environments by refining cost function weights},
  series = {CEAS Aeronautical Journal},
  journal   = {CEAS Aeronautical Journal},
  publisher = {Springer},
  address   = {Wien},
  issn      = {1869-5590 (eISSN)},
  doi       = {10.1007/s13272-024-00741-x},
  pages     = {12 Seiten},
  year      = {2024},
  abstract  = {Unmanned Aerial Vehicles (UAV) constantly gain in versatility. However, more reliable path planning algorithms are required until full autonomous UAV operation is possible. This work investigates the algorithm 3DVFH* and analyses its dependency on its cost function weights in 2400 environments. The analysis shows that the 3DVFH* can find a suitable path in every environment. However, a particular type of environment requires a specific choice of cost function weights. For minimal failure, probability interdependencies between the weights of the cost function have to be considered. This dependency reduces the number of control parameters and simplifies the usage of the 3DVFH*. Weights for costs associated with vertical evasion (pitch cost) and vicinity to obstacles (obstacle cost) have the highest influence on the failure probability of the local path planner. Environments with mainly very tall buildings (like large American city centres) require a preference for horizontal avoidance manoeuvres (achieved with high pitch cost weights). In contrast, environments with medium-to-low buildings (like European city centres) benefit from vertical avoidance manoeuvres (achieved with low pitch cost weights). The cost of the vicinity to obstacles also plays an essential role and must be chosen adequately for the environment. Choosing these two weights ideal is sufficient to reduce the failure probability below 10\%.},
  language  = {en}
}
@article{BoehnertBlaschkeBiewendt2023,
  author    = {B{\"o}hnert, Arno and Blaschke, Florian and Biewendt, Marcel},
  title     = {Impact of sustainability on the strategic direction of luxury companies},
  series = {European Journal of Marketing and Economics},
  volume    = {6},
  journal   = {European Journal of Marketing and Economics},
  number    = {1},
  publisher = {Revistia},
  address   = {London},
  issn      = {2601-8659},
  pages     = {70 -- 85},
  year      = {2023},
  abstract  = {Today's society is undergoing a paradigm shift driven by the megatrend of sustainability. This undeniably affects all areas of Western life. This paper aims to find out how the luxury industry is dealing with this change and what adjustments are made by the companies. For this purpose, interviews were conducted with managers from the luxury industry, in which they were asked about specific measures taken by their companies as well as trends in the industry. In a subsequent evaluation, the trends in the luxury industry were summarized for the areas of ecological, social, and economic sustainability. It was found that the area of environmental sustainability is significantly more focused than the other sub-areas. Furthermore, the need for a customer survey to validate the industry-based measures was identified.},
  language  = {en}
}
@article{BiewendtBlaschkeBoehnert2021,
  author    = {Biewendt, Marcel and Blaschke, Florian and B{\"o}hnert, Arno},
  title     = {Motivational factors in organisational change},
  series = {SocioEconomic Challenges},
  volume    = {5},
  journal   = {SocioEconomic Challenges},
  number    = {3},
  publisher = {ARMG},
  address   = {Sumy},
  issn      = {2520-6214},
  doi       = {10.21272/sec.5(3).15-27.2021},
  pages     = {15 -- 27},
  year      = {2021},
  abstract  = {The presented paper gives an overview of the most important and most common theories and concepts from the economic field of organisational change and is also enriched with quantitative publication data, which underlines the relevance of the topic. In particular, the topic presented is interwoven in an interdisciplinary way with economic psychological models, which are underpinned within the models with content from leading scholars in the field. The pace of change in companies is accelerating, as is technological change in our society. Adaptations of the corporate structure, but also of management techniques and tasks, are therefore indispensable. This includes not only the right approaches to employee motivation, but also the correct use of intrinsic and extrinsic motivational factors. Based on the hypothesis put forward by the scientist and researcher Rollinson in his book "Organisational behaviour and analysis" that managers believe motivational resources are available at all times, socio-economic and economic psychological theories are contrasted here in order to critically examine this statement. In addition, a fictitious company was created as a model for this work in order to illustrate the effects of motivational deficits in practice. In this context, the theories presented are applied to concrete problems within the model and conclusions are drawn about their influence and applicability. This led to the conclusion that motivation is a very individual challenge for each employee, which requires adapted and personalised approaches. On the other hand, the recommendations for action for supervisors in the case of motivation deficits also cannot be answered in a blanket manner, but can only be solved with the help of professional, expert-supported processing due to the economic-psychological realities of motivation. Identifying, analysing and remedying individual employee motivation deficits is, according to the authors, a problem and a challenge of great importance, especially in the context of rapidly changing ecosystems in modern companies, as motivation also influences other factors such as individual productivity. The authors therefore conclude that good motivation through the individual and customised promotion and further training of employees is an important point for achieving important corporate goals in order to remain competitive on the one hand and to create a productive and pleasant working environment on the other.},
  language  = {en}
}
@article{TixMollKrafftetal.2024,
  author    = {Tix, Julian and Moll, Fabian and Krafft, Simone and Betsch, Matthias and Tippk{\"o}tter, Nils},
  title     = {Hydrogen production from enzymatic pretreated organic waste with thermotoga neapolitana},
  series = {Energies},
  volume    = {17},
  journal   = {Energies},
  number    = {12},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1996-1073},
  doi       = {10.3390/en17122938},
  pages     = {20 Seiten},
  year      = {2024},
  abstract  = {Biomass from various types of organic waste was tested for possible use in hydrogen production. The composition consisted of lignified samples, green waste, and kitchen scraps such as fruit and vegetable peels and leftover food. For this purpose, the enzymatic pretreatment of organic waste with a combination of five different hydrolytic enzymes (cellulase, amylase, glucoamylase, pectinase and xylase) was investigated to determine its ability to produce hydrogen (H2) with the hydrolyzate produced here. In course, the anaerobic rod-shaped bacterium T. neapolitana was used for H2 production. First, the enzymes were investigated using different substrates in preliminary experiments. Subsequently, hydrolyses were carried out using different types of organic waste. In the hydrolysis carried out here for 48 h, an increase in glucose concentration of 481\% was measured for waste loads containing starch, corresponding to a glucose concentration at the end of hydrolysis of 7.5 g·L-1. In the subsequent set fermentation in serum bottles, a H2 yield of 1.26 mmol H2 was obtained in the overhead space when Terrific Broth Medium with glucose and yeast extract (TBGY medium) was used. When hydrolyzed organic waste was used, even a H2 yield of 1.37 mmol could be achieved in the overhead space. In addition, a dedicated reactor system for the anaerobic fermentation of T. neapolitana to produce H2 was developed. The bioreactor developed here can ferment anaerobically with a very low loss of produced gas. Here, after 24 h, a hydrogen concentration of 83\% could be measured in the overhead space.},
  language  = {en}
}
@article{BlockViebahnJungbluth2024,
  author    = {Block, Simon and Viebahn, Peter and Jungbluth, Christian},
  title     = {Analysing direct air capture for enabling negative emissions in Germany: an assessment of the resource requirements and costs of a potential rollout in 2045},
  series = {Frontiers in Climate},
  volume    = {6},
  journal   = {Frontiers in Climate},
  publisher = {Frontiers},
  address   = {Lausanne},
  issn      = {2624-9553},
  doi       = {10.3389/fclim.2024.1353939},
  pages     = {18 Seiten},
  year      = {2024},
  abstract  = {Direct air capture (DAC) combined with subsequent storage (DACCS) is discussed as one promising carbon dioxide removal option. The aim of this paper is to analyse and comparatively classify the resource consumption (land use, renewable energy and water) and costs of possible DAC implementation pathways for Germany. The paths are based on a selected, existing climate neutrality scenario that requires the removal of 20 Mt of carbon dioxide (CO2) per year by DACCS from 2045. The analysis focuses on the so-called "low-temperature" DAC process, which might be more advantageous for Germany than the "high-temperature" one. In four case studies, we examine potential sites in northern, central and southern Germany, thereby using the most suitable renewable energies for electricity and heat generation. We show that the deployment of DAC results in large-scale land use and high energy needs. The land use in the range of 167-353 km2 results mainly from the area required for renewable energy generation. The total electrical energy demand of 14.4 TWh per year, of which 46\% is needed to operate heat pumps to supply the heat demand of the DAC process, corresponds to around 1.4\% of Germany's envisaged electricity demand in 2045. 20 Mt of water are provided yearly, corresponding to 40\% of the city of Cologne's water demand (1.1 million inhabitants). The capture of CO2 (DAC) incurs levelised costs of 125-138 EUR per tonne of CO2, whereby the provision of the required energy via photovoltaics in southern Germany represents the lowest value of the four case studies. This does not include the costs associated with balancing its volatility. Taking into account transporting the CO2 via pipeline to the port of Wilhelmshaven, followed by transporting and sequestering the CO2 in geological storage sites in the Norwegian North Sea (DACCS), the levelised costs increase to 161-176 EUR/tCO2. Due to the longer transport distances from southern and central Germany, a northern German site using wind turbines would be the most favourable.},
  language  = {en}
}