@article{SchneiderSchneider2012,
  author    = {Schneider, Bettina and Schneider, Wilhelm},
  title     = {Grundlagen der Unternehmensbesteuerung},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {41},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {10},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {1312 -- 1318},
  year      = {2012},
  language  = {de}
}
@article{SchneiderSchneider2012,
  author    = {Schneider, Bettina and Schneider, Wilhelm},
  title     = {Externes Rechnungswesen nach BilMoG: Grundelemente und Aufbau},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {41},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {3},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {332 -- 337},
  year      = {2012},
  language  = {de}
}
@article{SchneiderSchneiderMeinhardtetal.2015,
  author    = {Schneider, Wilhelm and Schneider, Bettina and Meinhardt, Kerstin and Kinder, Stephanie},
  title     = {Die Fallstudie : Ermittlung des k{\"o}rperschaftssteuerlichen Einkommens und des Gewerbeertrags einer Kapitalgesellschaft},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {44},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {3},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {295 -- 298},
  year      = {2015},
  language  = {de}
}
@article{SchneiderSchneiderKinderetal.2017,
  author    = {Schneider, Wilhelm and Schneider, Bettina and Kinder, Stephanie and Meinhardt, Kerstin},
  title     = {Grundbegriffe der Abgabenordnung},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {46},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {5},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {575 -- 581},
  year      = {2017},
  language  = {de}
}
@article{SchneiderSchneider2007,
  author    = {Schneider, Bettina and Schneider, Wilhelm},
  title     = {Die Besteuerung des Unternehmens : K{\"o}rperschaft-, Gewerbe- und Umsatzsteuer},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {36},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {5},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {652 -- 655},
  year      = {2007},
  language  = {de}
}
@article{SchneiderSchneiderMeinhardtetal.2015,
  author    = {Schneider, Wilhelm and Schneider, Bettina and Meinhardt, Kerstin and Kinder, Stephanie},
  title     = {Allgemeines Steuerrecht},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {44},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {8-9},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {903 -- 910},
  year      = {2015},
  language  = {de}
}
@article{PietschHerzwurmJesse2006,
  author    = {Pietsch, Wolfram and Herzwurm, Georg and Jesse, Stefan},
  title     = {Der IT-Koordinator},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {35},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {2},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {184 -- 187},
  year      = {2006},
  language  = {de}
}
@article{FredebeulKrein2015,
  author    = {Fredebeul-Krein, Markus},
  title     = {Volkswirtschaftslehre : Die Klausur},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {45},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {11},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {1253 -- 1255},
  year      = {2015},
  language  = {de}
}
@article{FredebeulKrein2015,
  author    = {Fredebeul-Krein, Markus},
  title     = {Wettbewerbspolitische Leitbilder},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {45},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {4},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {483 -- 486},
  year      = {2015},
  language  = {de}
}
@article{SchneiderSchneider2009,
  author    = {Schneider, Bettina and Schneider, Wilhelm},
  title     = {Die Jahresabschlussanalyse},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {38},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {12},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {1594 -- 1600},
  year      = {2009},
  language  = {de}
}
@article{Tietze2009,
  author    = {Tietze, J{\"u}rgen},
  title     = {Die Elastizit{\"a}t {\"o}konomischer Funktionen},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {38},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {8/9},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  isbn      = {0340-3084},
  pages     = {1179 -- 1187},
  year      = {2009},
  language  = {de}
}
@article{SchneiderSchneider2006,
  author    = {Schneider, Bettina and Schneider, Wilhelm},
  title     = {Studienfinanzierung: So kommt man an ein Stipendium},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {35},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {12},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {1500 -- 1502},
  year      = {2006},
  language  = {de}
}
@article{SchneiderSchneider2007,
  author    = {Schneider, Bettina and Schneider, Wilhelm},
  title     = {Die Besteuerung des Unternehmens - Grundlagen und Einkommensteuer},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {36},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {4},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {476 -- 480},
  year      = {2007},
  language  = {de}
}
@article{Call2002,
  author    = {Call, Guido},
  title     = {Versandhandel und eCommerce: Kannibalisierung oder Erg{\"a}nzung},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {31},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {12},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {1535 -- 1540},
  year      = {2002},
  language  = {de}
}
@article{SchneiderSchneider2010,
  author    = {Schneider, Bettina and Schneider, Wilhelm},
  title     = {Die Fallstudie: Konzernrechnungslegung},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {39},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {11},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {1495 -- 1498},
  year      = {2010},
  language  = {de}
}
@article{Pietsch2004,
  author    = {Pietsch, Wolfram},
  title     = {IT Service Level Agreements},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {33},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {11},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {1366 -- 1369},
  year      = {2004},
  language  = {de}
}
@article{Ritz2006,
  author    = {Ritz, Thomas},
  title     = {Mobile Unternehmenssoftware},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {36},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {10},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {1212 -- 1218},
  year      = {2006},
  language  = {de}
}
@article{Call2001,
  author    = {Call, Guido},
  title     = {Analyse des Sortimentverbunds},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {30},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {11},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {1501 -- 1507},
  year      = {2001},
  language  = {de}
}
@article{Call2003,
  author    = {Call, Guido},
  title     = {Couponing},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {32},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {11},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {1372 -- 1377},
  year      = {2003},
  language  = {de}
}
@article{SchneiderSchneiderMeinhardtetal.2015,
  author    = {Schneider, Wilhelm and Schneider, Bettina and Meinhardt, Kerstin and Kinder, Stephanie},
  title     = {Die Fallstudie : Aufstellung eines Anlagespiegels},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {44},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {5},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {580 -- 582},
  year      = {2015},
  language  = {de}
}
@article{SchneiderSchneider2010,
  author    = {Schneider, Bettina and Schneider, Wilhelm},
  title     = {Die Konzernrechnungslegung},
  series = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  volume    = {39},
  journal   = {Das Wirtschaftsstudium : WISU ; Zeitschrift f{\"u}r Ausbildung, Examen und Weiterbildung},
  number    = {7},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {938 -- 942},
  year      = {2010},
  language  = {de}
}
@article{SanchezCespedesLeasureTejedorGaravitoetal.2023,
  author    = {Sanchez-Cespedes, Lina Maria and Leasure, Douglas Ryan and Tejedor-Garavito, Natalia and Amaya Cruz, Glenn Harry and Garcia Velez, Gustavo Adolfo and Mendoza Beltr{\´a}n, Andryu Enrique and Mar{\´i}n-Salazar, Yenny Andrea and Esch, Thomas and Tatem, Andrew J. and Ospina Boh{\´o}rquez, Mariana Francisca},
  title     = {Social cartography and satellite-derived building coverage for post-census population estimates in difficult-to-access regions of Colombia},
  series = {Population studies : a Journal of Demography},
  volume    = {78},
  journal   = {Population studies : a Journal of Demography},
  number    = {1},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {1477-4747},
  doi       = {10.1080/00324728.2023.2190151},
  pages     = {3 -- 20},
  year      = {2023},
  abstract  = {Effective government services rely on accurate population numbers to allocate resources. In Colombia and globally, census enumeration is challenging in remote regions and where armed conflict is occurring. During census preparations, the Colombian National Administrative Department of Statistics conducted social cartography workshops, where community representatives estimated numbers of dwellings and people throughout their regions. We repurposed this information, combining it with remotely sensed buildings data and other geospatial data. To estimate building counts and population sizes, we developed hierarchical Bayesian models, trained using nearby full-coverage census enumerations and assessed using 10-fold cross-validation. We compared models to assess the relative contributions of community knowledge, remotely sensed buildings, and their combination to model fit. The Community model was unbiased but imprecise; the Satellite model was more precise but biased; and the Combination model was best for overall accuracy. Results reaffirmed the power of remotely sensed buildings data for population estimation and highlighted the value of incorporating local knowledge.},
  language  = {en}
}
@article{BogoyavlenskiyDigelBerezin1997,
  author    = {Bogoyavlenskiy, Andrey P. and Digel, Ilya and Berezin, Vladimir E.},
  title     = {Assessment of dot-blot ELISA sensitivity on membrane sorbent using various peroxidase substrates},
  year      = {1997},
  abstract  = {The sensitivity of the peroxidase reaction in dot-blot ELISA significantly depends on the substrate. The highest sensitivity is observed using benzidine and diamine- phenol combinations as the substrates due to the reaction of the coupled oxidation (NADI)},
  subject      = {Enzyme-linked immunosorbent assay},
  language  = {en}
}
@article{KernBeierlZischank2009,
  author    = {Kern, Alexander and Beierl, Ottmar and Zischank, Wolfgang},
  title     = {DIN EN 62 305-3 - Berechnung des Trennungsabstands (Anmerkungen zur Anwendung der Berechnungsverfahren und vereinfachte Verfahren zur Absch{\"a}tzung der Stromaufteilung) / Kern, A. ; Beierl, O. ; Zischank, W.},
  series = {Elektropraktiker. 63 (2009), H. 3},
  journal   = {Elektropraktiker. 63 (2009), H. 3},
  publisher = {HUSS-MEDIEN GmbH},
  address   = {Berlin},
  isbn      = {0013-5569},
  pages     = {218 -- 222},
  year      = {2009},
  language  = {de}
}
@article{JanzBeiseEblingetal.1999,
  author    = {Janz, Norbert and Beise, Marian and Ebling, G{\"u}nther and Licht, Georg},
  title     = {Innovationsaktivit{\"a}ten im verarbeitenden Gewerbe: Ergebnisse der Innovationserhebung 1997 / Beise, M., G. Ebling, N. Janz, G. Licht und H. Niggemann},
  series = {Innovationsaktivit{\"a}ten in der deutschen Wirtschaft : Analyse der Mannheimer Innovationspanels im Verarbeitenden Gewerbe und im Dienstleistungssektor / Norbert Janz ... (Hrsg.)},
  journal   = {Innovationsaktivit{\"a}ten in der deutschen Wirtschaft : Analyse der Mannheimer Innovationspanels im Verarbeitenden Gewerbe und im Dienstleistungssektor / Norbert Janz ... (Hrsg.)},
  publisher = {Nomos-Verl.-Ges.},
  address   = {Baden-Baden},
  isbn      = {3-7890-6179-4},
  pages     = {9 -- 98},
  year      = {1999},
  language  = {de}
}
@article{BogoyavlenskiyBerezinOgnevaetal.1999,
  author    = {Bogoyavlenskiy, Andrey P. and Berezin, Vladimir E. and Ogneva, A. V. and Tolmacheva, V. P. and Digel, Ilya and Khudyakova, S. S.},
  title     = {Immunostimulating activity of a saponin-containing extract of Saponaria officinalis},
  series = {Voprosy virusologii},
  volume    = {44},
  journal   = {Voprosy virusologii},
  number    = {5},
  issn      = {0507-4088},
  pages     = {229 -- 232},
  year      = {1999},
  language  = {en}
}
@article{AlexyukBogoyavlenskiyAlexyuketal.2021,
  author    = {Alexyuk, Madina and Bogoyavlenskiy, Andrey and Alexyuk, Pavel and Moldakhanov, Yergali and Berezin, Vladimir E. and Digel, Ilya},
  title     = {Epipelagic microbiome of the Small Aral Sea: Metagenomic structure and ecological diversity},
  series = {MicrobiologyOpen},
  volume    = {10},
  journal   = {MicrobiologyOpen},
  number    = {1},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {2045-8827},
  doi       = {10.1002/mbo3.1142},
  pages     = {1 -- 10},
  year      = {2021},
  abstract  = {Microbial diversity studies regarding the aquatic communities that experienced or are experiencing environmental problems are essential for the comprehension of the remediation dynamics. In this pilot study, we present data on the phylogenetic and ecological structure of microorganisms from epipelagic water samples collected in the Small Aral Sea (SAS). The raw data were generated by massive parallel sequencing using the shotgun approach. As expected, most of the identified DNA sequences belonged to Terrabacteria and Actinobacteria (40\% and 37\% of the total reads, respectively). The occurrence of Deinococcus-Thermus, Armatimonadetes, Chloroflexi in the epipelagic SAS waters was less anticipated. Surprising was also the detection of sequences, which are characteristic for strict anaerobes—Ignavibacteria, hydrogen-oxidizing bacteria, and archaeal methanogenic species. We suppose that the observed very broad range of phylogenetic and ecological features displayed by the SAS reads demonstrates a more intensive mixing of water masses originating from diverse ecological niches of the Aral-Syr Darya River basin than presumed before.},
  language  = {en}
}
@article{RibitschHeumannKarletal.2012,
  author    = {Ribitsch, Doris and Heumann, Sonja and Karl, Wolfgang and Gerlach, Jochen and Leber, Regina and Birner-Gruenberger, Ruth and Gruber, Karl and Eiteljoerg, Inge and Remler, Peter and Siegert, Petra and Lange, Jennifer and Maurer, Karl-Heinz and Berg, Gabriele and Guebitz, G. M. and Schwab, H.},
  title     = {Extracellular serine proteases from Stenotrophomonas maltophilia: Screening, isolation and heterologous expression in E. coli},
  series = {Journal of biotechnology},
  volume    = {157},
  journal   = {Journal of biotechnology},
  number    = {1},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-4863 (E-Journal); 0168-1656 (Print)},
  doi       = {10.1016/j.jbiotec.2011.09.025},
  pages     = {140 -- 147},
  year      = {2012},
  abstract  = {A large strain collection comprising antagonistic bacteria was screened for novel detergent proteases. Several strains displayed protease activity on agar plates containing skim milk but were inactive in liquid media. Encapsulation of cells in alginate beads induced protease production. Stenotrophomonas maltophilia emerged as best performer under washing conditions. For identification of wash-active proteases, four extracellular serine proteases called StmPr1, StmPr2, StmPr3 and StmPr4 were cloned. StmPr2 and StmPr4 were sufficiently overexpressed in E. coli. Expression of StmPr1 and StmPr3 resulted in unprocessed, insoluble protein. Truncation of most of the C-terminal domain which has been identified by enzyme modeling succeeded in expression of soluble, active StmPr1 but failed in case of StmPr3. From laundry application tests StmPr2 turned out to be a highly wash-active protease at 45 °C. Specific activity of StmPr2 determined with suc-l-Ala-l-Ala-l-Pro-l-Phe-p-nitroanilide as the substrate was 17 ± 2 U/mg. In addition we determined the kinetic parameters and cleavage preferences of protease StmPr2.},
  language  = {en}
}
@article{ChristenKowalskiBartelt2010,
  author    = {Christen, Marc and Kowalski, Julia and Bartelt, Perry},
  title     = {RAMMS: Numerical simulation of dense snow avalanches in three-dimensional terrain},
  series = {Cold Regions Science and Technology},
  volume    = {63},
  journal   = {Cold Regions Science and Technology},
  number    = {1-2},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1872-7441},
  doi       = {10.1016/j.coldregions.2010.04.005},
  pages     = {1 -- 14},
  year      = {2010},
  abstract  = {Numerical avalanche dynamics models have become an essential part of snow engineering. Coupled with field observations and historical records, they are especially helpful in understanding avalanche flow in complex terrain. However, their application poses several new challenges to avalanche engineers. A detailed understanding of the avalanche phenomena is required to construct hazard scenarios which involve the careful specification of initial conditions (release zone location and dimensions) and definition of appropriate friction parameters. The interpretation of simulation results requires an understanding of the numerical solution schemes and easy to use visualization tools. We discuss these problems by presenting the computer model RAMMS, which was specially designed by the SLF as a practical tool for avalanche engineers. RAMMS solves the depth-averaged equations governing avalanche flow with accurate second-order numerical solution schemes. The model allows the specification of multiple release zones in three-dimensional terrain. Snow cover entrainment is considered. Furthermore, two different flow rheologies can be applied: the standard Voellmy-Salm (VS) approach or a random kinetic energy (RKE) model, which accounts for the random motion and inelastic interaction between snow granules. We present the governing differential equations, highlight some of the input and output features of RAMMS and then apply the models with entrainment to simulate two well-documented avalanche events recorded at the Vall{\´e}e de la Sionne test site.},
  language  = {en}
}
@article{HerzogPietrzykShahetal.2010,
  author    = {Herzog, Hans and Pietrzyk, Uwe and Shah, N. Jon and Ziemons, Karl},
  title     = {The current state, challenges and perspectives of MR-PET},
  series = {Neuroimage},
  volume    = {49},
  journal   = {Neuroimage},
  number    = {3},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1053-8119},
  doi       = {10.1016/j.neuroimage.2009.10.036},
  pages     = {2072 -- 2082},
  year      = {2010},
  abstract  = {Following the success of PET/CT during the last decade and the recent increasing proliferation of SPECT/CT, another hybrid imaging instrument has been gaining more and more interest: MR-PET. First combined, simultaneous PET and MR studies carried out in small animals demonstrated the feasibility of the new approach. Concurrently, some prototypes of an MR-PET scanner for simultaneous human brain studies have been built, their performance is being tested and preliminary applications have already been shown. Through this pioneering work, it has become clear that advances in the detector design are necessary for further optimization. Recently, the different issues related to the present state and future prospects of MR-PET were presented and discussed during an international 2-day workshop at the Forschungszentrum J{\"u}lich, Germany, held after, and in conjunction with, the 2008 IEEE Nuclear Science Symposium and Medical Imaging Conference in Dresden, Germany on October 27-28, 2008. The topics ranged from small animal MR-PET imaging to human MR-BrainPET imaging, new detector developments, challenges/opportunities for ultra-high field MR-PET imaging and considerations of possible future research and clinical applications. This report presents a critical summary of the contributions made to the workshop.},
  language  = {en}
}
@article{OlbertzThiergart2010,
  author    = {Olbertz, Klaus and Thiergart, Kirsten},
  title     = {B{\"o}rsengang leicht gemacht? Gesellschafts- und arbeitsrechtliche Aspekte bei {\"U}bernahme und Verschmelzung eines Zielunternehmens auf die SPAC in der Rechtsform der SE},
  series = {Betriebs-Berater: BB ; Recht, Wirtschaft, Steuern},
  journal   = {Betriebs-Berater: BB ; Recht, Wirtschaft, Steuern},
  publisher = {Beck},
  address   = {M{\"u}nchen},
  issn      = {0340-7918},
  pages     = {1547},
  year      = {2010},
  abstract  = {Die SPAC-SE ist b{\"o}rsenf{\"a}hig und damit eine f{\"u}r eine SPAC grunds{\"a}tzlich geeignete Rechtsform. Die Tatsache, dass es sich hierbei (zun{\"a}chst) um eine leere, arbeitnehmerlose H{\"u}lle handelt, {\"a}ndert hieran nichts. Die Gr{\"u}ndung einer solchen Vorrats-SE ist trotz fehlender Arbeitnehmerbeteiligung unter teleologischer Reduktion von Art. 12 II SE-VO zul{\"a}ssig. Im Gegenzug muss die Arbeitnehmerbeteiligung gemaß \S 18 III SEBG analog nachgeholt werden, wenn das sp{\"a}ter erworbene Zielunternehmen auf die SPAC-SE verschmolzen werden soll. Aus gesellschaftsrechtlicher Sicht ist zu beachten, dass die SPAC-SE mit Sitz in Deutschland, welche auch den deutschen, aktienrechtlichen Bestimmungen unterliegt, nur bedingt f{\"u}r eine SPAC geeignet erscheint. Das deutsche Aktienrecht enth{\"a}lt strenge Regelungen, die der f{\"u}r eine SPAC-SE erforderlichen Flexibilit{\"a}t entgegenstehen k{\"o}nnen. Dies gilt insbesondere f{\"u}r das Erfordernis der Zustimmung der Hauptversammlung zur Akquisition des Zielunternehmens, die R{\"u}ckzahlung des Treuhandverm{\"o}gens an Aktion{\"a}re, die der Akquisition nicht zugestimmt haben und die Liquidation der SPAC-SE im Falle des Scheiterns des Erwerbs des Zielobjektes.},
  language  = {de}
}
@article{RiglingEilmannKoechlietal.2010,
  author    = {Rigling, Andreas and Eilmann, Britta and Koechli, Roger and Dobbertin, Matthias},
  title     = {Mistletoe-induced crown degradation in Scots pine in a xeric environment},
  series = {Tree Physiology},
  volume    = {30},
  journal   = {Tree Physiology},
  number    = {7},
  publisher = {Oxford University Press},
  address   = {Oxford},
  issn      = {1758-4469 (Online)},
  doi       = {10.1093/treephys/tpq038},
  pages     = {845 -- 832},
  year      = {2010},
  abstract  = {Increasing Scots pine (Pinus sylvestris L.) mortality has been recently observed in the dry inner valleys of the European Alps. Besides drought, infection with pine mistletoe (Viscum album ssp. austriacum) seems to play an important role in the mortality dynamics of Scots pines, but how mistletoes promote pine decline remains unclear. To verify whether pine mistletoe infection weakens the host via crown degradation, as observed for dwarf mistletoes, we studied the negative effects of pine mistletoe infestation on the photosynthetic tissues and branch growth of pairs of infested and non-infested branches. Pine mistletoe infection leads to crown degradation in its host by reducing the length, the radial increment, the ramification, the needle length and the number of needle years of the infested branches. This massive loss in photosynthetic tissue results in a reduction in primary production and a subsequent decrease in carbohydrate availability. The significant reduction in needle length due to mistletoe infection is an indication for a lower water and nutrient availability in infested branches. Thus, mistletoe infection might lead to a decrease in the availability of water and carbohydrates, the two most important growth factors, which are already shortened due to the chronic drought situation in the area. Therefore, pine mistletoe increases the risk of drought-induced mortality of its host when growing in a xeric environment.},
  language  = {en}
}
@article{KirchnerOberlaenderFriedrichetal.2010,
  author    = {Kirchner, Patrick and Oberl{\"a}nder, Jan and Friedrich, Peter and Rysstad, Gunnar and Berger, J{\"o}rg and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Realization of a calorimetric gas sensor on polyimide foil for applications in aseptic food industry},
  series = {Procedia Engineering},
  volume    = {5},
  journal   = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2010.09.098},
  pages     = {264 -- 267},
  year      = {2010},
  abstract  = {A calorimetric gas sensor is presented for the monitoring of gas-phase H2O2 at elevated temperature during sterilization processes in aseptic food industry. The sensor consists of two temperature-sensitive thin-film resistances built up on a polyimide foil with a thickness of 25 μm, which are passivated with a layer of SU-8 photo resist and catalytically activated with manganese(IV) oxide. Instead of an active heating structure, the calorimetric sensor utilizes the elevated temperature of an evaporated H2O2 aerosol. In an experimental set-up, the sensor has shown a sensitivity of 4.78 °C/(\%v/v) in a H2O2 concentration range of 0 to 10\% v/v at an evaporation temperature of 240 ∘C. Furthermore, the sensor possesses the same, unchanged sensor signal even at varied evaporation temperatures of the gas stream. The sensor characterization demonstrates the suitability of the calorimetric gas sensor for monitoring the efficiency of sterilization processes.},
  language  = {en}
}
@article{WagnerMiyamotoSchoeningetal.2010,
  author    = {Wagner, Torsten and Miyamoto, Ko-ichiro and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo},
  title     = {Novel combination of digital light processing (DLP) and light-addressable potentiometric sensors (LAPS) for flexible chemical imaging},
  series = {Procedia Engineering},
  volume    = {5},
  journal   = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2010.09.161},
  pages     = {520 -- 523},
  year      = {2010},
  abstract  = {Chemical imaging systems allow the visualisation of the distribution of chemical species on the sensor surface. This work represents a new flexible approach of read out in a light-addressable potentiometric sensor (LAPS) with the help of a digital light processing (DLP) set-up. The DLP, known well for video projectors, consists of a mirror-array MEMS device which allows fast and flexible generation of light patterns. With the help of these light patterns the sensor surface of the LAPS device can be read out sequentially in a raster like scheme (scanning LAPS). The DLP approach has several advantages compared to conventional scanning LAPS set-ups, e.g., the spot size, the shape and the intensity of the light pointer can be changed easily and no mechanical movement is necessary, which reduces the size of the set-up and increases the stability and speed of measurement.},
  language  = {en}
}
@article{MiyamotoKanekoMatsuoetal.2010,
  author    = {Miyamoto, Ko-ichiro and Kaneko, Kazumi and Matsuo, Akira and Wagner, Torsten and Kanoh, Shin`ichiro and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo},
  title     = {Miniaturized chemical imaging sensor system using an OLED display panel},
  series = {Procedia Engineering},
  volume    = {5},
  journal   = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2010.09.160},
  pages     = {516 -- 519},
  year      = {2010},
  abstract  = {The chemical imaging sensor is a semiconductor-based chemical sensor that can visualize the two-dimensional distribution of specific ions or molecules in the solution. In this study, we developed a miniaturized chemical imaging sensor system with an OLED display panel as a light source that scans the sensor plate. In the proposed configuration, the display panel is placed directly below the sensor plate and illuminates the back surface. The measured area defined by illumination can be arbitrarily customized to fit the size and the shape of the sample to be measured. The waveform of the generated photocurrent, the currentvoltage characteristics and the pH sensitivity were investigated and pH imaging with this miniaturized system was demonstrated.},
  language  = {en}
}
@article{SrivastavaSinghAggarwaletal.2010,
  author    = {Srivastava, Alok and Singh, Virendra and Aggarwal, Pranav and Schneeweiss, F. and Scherer, Ulrich W. and Friedrich, W.},
  title     = {Optical studies of insulating polymers for radiation dose monitoring},
  series = {Indian Journal of Pure and Applied Physics},
  volume    = {48},
  journal   = {Indian Journal of Pure and Applied Physics},
  number    = {11},
  publisher = {Council Of Scientific And Industrial Research (CSIR), National Institute Of Science Communication and Policy Research (NIScPR)},
  address   = {New Delhi},
  isbn      = {0019-5596},
  pages     = {782 -- 786},
  year      = {2010},
  abstract  = {The optical study carried out on insulating polymers namely polyethyleneterephthalate (PET) and polyvinylchloride (PVC) has been described. The polymers are exposed to different radiation doses by exposing them to swift heavy ions of carbon (90 MeV), silicon (120 MeV) and nickel (100 MeV) which influence on their optical properties. The studies show that amongst the investigated polymers, PVC and PET have potential for application as dosimeter beyond a threshold dose which is strongly dependent on the nature of the material and the radiation type. The optical micrographs show a distinct change in colour of the sample with increase in radiation dose.},
  language  = {en}
}
@article{AbouzarPedrazaSchoeningetal.2010,
  author    = {Abouzar, Maryam H. and Pedraza, A. M. and Sch{\"o}ning, Michael Josef and Poghossian, Arshak},
  title     = {Label-free DNA hybridization and denaturation detection by means of field-effect nanoplate SOI capacitors functionalized with gold nanoparticles},
  series = {Procedia Engineering},
  volume    = {5},
  journal   = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2010.09.259},
  pages     = {918 -- 921},
  year      = {2010},
  abstract  = {A new approach for a label-free electrical detection of DNA hybridization and denaturation using an array of individually addressable field-effect nanoplate SOI (silicon-on-insulator) capacitors functionalized with gold nanoparticles is presented. By using a constant-capacitance measuring setup in a differential mode, signal changes of ∼110 mV and ∼70 mV have been registered after the DNA hybridization and denaturation events, respectively.},
  language  = {en}
}
@article{GebhardtSchmidtHoetteretal.2010,
  author    = {Gebhardt, Andreas and Schmidt, Frank-Michael and H{\"o}tter, Jan-Steffen and Sokalla, Wolfgang and Sokalla, Patrick},
  title     = {Additive manufacturing by selective laser melting the realizer desktop machine and its application for the dental industry},
  series = {Physics Procedia},
  volume    = {5 B},
  journal   = {Physics Procedia},
  number    = {2},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1875-3892},
  doi       = {10.1016/j.phpro.2010.08.082},
  pages     = {543 -- 549},
  year      = {2010},
  abstract  = {Additive Manufacturing of metal parts by Selective Laser Melting has become a powerful tool for the direct manufacturing of complex parts mainly for the aerospace and medical industry. With the introduction of its desktop machine, Realizer targeted the dental market. The contribution describes the special features of the machine, discusses details of the process and shows manufacturing results focused on metal dental devices.},
  language  = {en}
}
@article{BohrnStuetzFleischeretal.2010,
  author    = {Bohrn, Ulrich and St{\"u}tz, Evamaria and Fleischer, Maximilian and Sch{\"o}ning, Michael Josef},
  title     = {Real-time detection of CO by eukaryotic cells},
  series = {Procedia Engineering},
  volume    = {5},
  journal   = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  pages     = {17 -- 20},
  year      = {2010},
  abstract  = {In this contribution, we focus on the detection of toxic gases with living eukaryotic cells. A cell-based gas sensor system, able to measure the effects of direct exposure of gases to cells in real-time, was set up. Impedance data as well as oxygen consumption of Chinese hamster lung fibroblast cells (V79) were analysed upon exposure to carbon monoxide (CO). The CO (diluted in wet synthetic air) affects the cell respiration as indicated by an attenuated respiration signal after the CO exposure as well as an instant increase of the capacitive part of the impedance signal during the gas exposure.},
  language  = {en}
}
@article{MuellerSeginWeigandetal.2022,
  author    = {Mueller, Tobias and Segin, Alexander and Weigand, Christoph and Schmitt, Robert H.},
  title     = {Feature selection for measurement models},
  series = {International journal of quality \& reliability management},
  journal   = {International journal of quality \& reliability management},
  number    = {Vol. ahead-of-print, No. ahead-of-print.},
  publisher = {Emerald Group Publishing Limited},
  address   = {Bingley},
  issn      = {0265-671X},
  doi       = {10.1108/IJQRM-07-2021-0245},
  year      = {2022},
  abstract  = {Purpose In the determination of the measurement uncertainty, the GUM procedure requires the building of a measurement model that establishes a functional relationship between the measurand and all influencing quantities. Since the effort of modelling as well as quantifying the measurement uncertainties depend on the number of influencing quantities considered, the aim of this study is to determine relevant influencing quantities and to remove irrelevant ones from the dataset. Design/methodology/approach In this work, it was investigated whether the effort of modelling for the determination of measurement uncertainty can be reduced by the use of feature selection (FS) methods. For this purpose, 9 different FS methods were tested on 16 artificial test datasets, whose properties (number of data points, number of features, complexity, features with low influence and redundant features) were varied via a design of experiments. Findings Based on a success metric, the stability, universality and complexity of the method, two FS methods could be identified that reliably identify relevant and irrelevant influencing quantities for a measurement model. Originality/value For the first time, FS methods were applied to datasets with properties of classical measurement processes. The simulation-based results serve as a basis for further research in the field of FS for measurement models. The identified algorithms will be applied to real measurement processes in the future.},
  language  = {en}
}
@article{FerreinRensMeyeretal.2011,
  author    = {Ferrein, Alexander and Rens, Gavin and Meyer, Thomas and Lakemeyer, Gerhard},
  title     = {A Logic for Specifying Partially Observable Stochastic Domains},
  series = {Proceedings of the Ninth International Workshop pn non-Monotonic Reasoning, Action and Change (NRAC`11)},
  journal   = {Proceedings of the Ninth International Workshop pn non-Monotonic Reasoning, Action and Change (NRAC`11)},
  pages     = {15 -- 22},
  year      = {2011},
  language  = {en}
}
@article{OehlenschlaegerVolkmarStiefelmaieretal.2024,
  author    = {Oehlenschl{\"a}ger, Katharina and Volkmar, Marianne and Stiefelmaier, Judith and Langsdorf, Alexander and Holtmann, Dirk and Tippk{\"o}tter, Nils and Ulber, Roland},
  title     = {New insights into the influence of pre-culture on robust solvent production of C. acetobutylicum},
  series = {Applied Microbiology and Biotechnology},
  volume    = {108},
  journal   = {Applied Microbiology and Biotechnology},
  publisher = {Springer},
  address   = {Berlin, Heidelberg},
  issn      = {1432-0614},
  doi       = {10.1007/s00253-023-12981-8},
  pages     = {10 Seiten},
  year      = {2024},
  abstract  = {Clostridia are known for their solvent production, especially the production of butanol. Concerning the projected depletion of fossil fuels, this is of great interest. The cultivation of clostridia is known to be challenging, and it is difficult to achieve reproducible results and robust processes. However, existing publications usually concentrate on the cultivation conditions of the main culture. In this paper, the influence of cryo-conservation and pre-culture on growth and solvent production in the resulting main cultivation are examined. A protocol was developed that leads to reproducible cultivations of Clostridium acetobutylicum. Detailed investigation of the cell conservation in cryo-cultures ensured reliable cell growth in the pre-culture. Moreover, a reason for the acid crash in the main culture was found, based on the cultivation conditions of the pre-culture. The critical parameter to avoid the acid crash and accomplish the shift to the solventogenesis of clostridia is the metabolic phase in which the cells of the pre-culture were at the time of inoculation of the main culture; this depends on the cultivation time of the pre-culture. Using cells from the exponential growth phase to inoculate the main culture leads to an acid crash. To achieve the solventogenic phase with butanol production, the inoculum should consist of older cells which are in the stationary growth phase. Considering these parameters, which affect the entire cultivation process, reproducible results and reliable solvent production are ensured.},
  language  = {en}
}
@article{HengsbachEngelCwienczeketal.2023,
  author    = {Hengsbach, Jan-Niklas and Engel, Mareike and Cwienczek, Marcel and Stiefelmaier, Judith and Tippk{\"o}tter, Nils and Ulber, Roland},
  title     = {Scalable unseparated bioelectrochemical reactors by using a carbon fiber brush as stirrer and working electrode},
  series = {ChemElectroChem},
  volume    = {10},
  journal   = {ChemElectroChem},
  number    = {21},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {2196-0216},
  doi       = {10.1002/celc.202300440},
  pages     = {9 Seiten},
  year      = {2023},
  abstract  = {The concept of energy conversion into platform chemicals using bioelectrochemical systems (BES) has gained increasing attention in recent years, as the technology simultaneously provides an opportunity for sustainable chemical production and tackles the challenge of Power-to-X technologies. There are many approaches to realize the industrial scale of BES. One concept is to equip standard bioreactors with static electrodes. However, large installations resulted in a negative influence on various reactor parameters. In this study, we present a new single-chamber BES based on a stirred tank reactor in which the stirrer was replaced by a carbon fiber brush, performing the functions of the working electrode and the stirrer. The reactor is characterized in abiotic studies and electro-fermentations with Clostridium acetobutylicum. Compared to standard reactors an increase in butanol production of 20.14±3.66 \% shows that the new BES can be efficiently used for bioelectrochemical processes.},
  language  = {en}
}
@article{Finkenberger2014,
  author    = {Finkenberger, Isabel Maria},
  title     = {Vox populi. (Transformations-)potenziale nachkriegsmoderner Freiraumressourcen},
  series = {Stadt+Gr{\"u}n},
  volume    = {2014},
  journal   = {Stadt+Gr{\"u}n},
  number    = {1},
  publisher = {Patzer},
  address   = {Berlin},
  issn      = {0948-9770},
  pages     = {31 -- 35},
  year      = {2014},
  abstract  = {Heute wie damals werden die großz{\"u}gigen und offenen Siedlungsstrukturen der ersten Nachkriegsjahrzehnte mit ihrem hohen Anteil an "Gr{\"u}n" vielfach gesch{\"a}tzt und als solche nicht grundlegend hinterfragt. "Gr{\"u}n" verheißt im Allgemeinen Licht, Luft und Sonne, Freizeit und Erholung und gilt als etwas W{\"u}nschenswertes im st{\"a}dtischen Kontext. Unbeachtet bleibt, dass dem Begriff "Gr{\"u}n" zun{\"a}chst keine Eigenschaften oder Qualit{\"a}ten zugewiesen sind - er sagt noch lange nichts {\"u}ber dessen r{\"a}umliche Qualit{\"a}t, dessen Nutzbarkeit, Erreichbarkeit und Zug{\"a}nglichkeit aus. Abstandsgr{\"u}n und Straßenbegleitgr{\"u}n ist eben auch "Gr{\"u}n". Neben einer quantitativen Argumentation, welche {\"o}kologischen Aspekte wie Biotopvernetzung, Stadt- und Mikroklima ber{\"u}cksichtigt, sollten wir verst{\"a}rkt qualitativ denken und damit die Grundlage f{\"u}r einen erweiterten und wesentlich differenzierteren Diskurs {\"u}ber urbane Freir{\"a}ume ebnen.},
  language  = {de}
}
@article{DitzhausGaigall2022,
  author    = {Ditzhaus, Marc and Gaigall, Daniel},
  title     = {Testing marginal homogeneity in Hilbert spaces with applications to stock market returns},
  series = {Test},
  volume    = {2022},
  journal   = {Test},
  number    = {31},
  publisher = {Springer},
  issn      = {1863-8260},
  doi       = {10.1007/s11749-022-00802-5},
  pages     = {749 -- 770},
  year      = {2022},
  abstract  = {This paper considers a paired data framework and discusses the question of marginal homogeneity of bivariate high-dimensional or functional data. The related testing problem can be endowed into a more general setting for paired random variables taking values in a general Hilbert space. To address this problem, a Cram{\´e}r-von-Mises type test statistic is applied and a bootstrap procedure is suggested to obtain critical values and finally a consistent test. The desired properties of a bootstrap test can be derived that are asymptotic exactness under the null hypothesis and consistency under alternatives. Simulations show the quality of the test in the finite sample case. A possible application is the comparison of two possibly dependent stock market returns based on functional data. The approach is demonstrated based on historical data for different stock market indices.},
  language  = {en}
}
@article{GrajewskiKleefeld2023,
  author    = {Grajewski, Matthias and Kleefeld, Andreas},
  title     = {Detecting and approximating decision boundaries in low-dimensional spaces},
  series = {Numerical Algorithms},
  volume    = {93},
  journal   = {Numerical Algorithms},
  number    = {4},
  publisher = {Springer Science+Business Media},
  address   = {Dordrecht},
  issn      = {1572-9265},
  pages     = {35 Seiten},
  year      = {2023},
  abstract  = {A method for detecting and approximating fault lines or surfaces, respectively, or decision curves in two and three dimensions with guaranteed accuracy is presented. Reformulated as a classification problem, our method starts from a set of scattered points along with the corresponding classification algorithm to construct a representation of a decision curve by points with prescribed maximal distance to the true decision curve. Hereby, our algorithm ensures that the representing point set covers the decision curve in its entire extent and features local refinement based on the geometric properties of the decision curve. We demonstrate applications of our method to problems related to the detection of faults, to multi-criteria decision aid and, in combination with Kirsch's factorization method, to solving an inverse acoustic scattering problem. In all applications we considered in this work, our method requires significantly less pointwise classifications than previously employed algorithms.},
  language  = {en}
}
@article{HaegerProbstJaegeretal.2023,
  author    = {Haeger, Gerrit and Probst, Johanna and Jaeger, Karl-Erich and Bongaerts, Johannes and Siegert, Petra},
  title     = {Novel aminoacylases from Streptomyces griseus DSM 40236 and their recombinant production in Streptomyces lividans},
  series = {FEBS Open Bio},
  volume    = {13},
  journal   = {FEBS Open Bio},
  number    = {12},
  publisher = {Wiley},
  address   = {Hoboken, NJ},
  issn      = {2211-5463},
  doi       = {10.1002/2211-5463.13723},
  pages     = {2224 -- 2238},
  year      = {2023},
  abstract  = {Amino acid-based surfactants are valuable compounds for cosmetic formulations. The chemical synthesis of acyl-amino acids is conventionally performed by the Schotten-Baumann reaction using fatty acyl chlorides, but aminoacylases have also been investigated for use in biocatalytic synthesis with free fatty acids. Aminoacylases and their properties are diverse; they belong to different peptidase families and show differences in substrate specificity and biocatalytic potential. Bacterial aminoacylases capable of synthesis have been isolated from Burkholderia, Mycolicibacterium, and Streptomyces. Although several proteases and peptidases from S. griseus have been described, no aminoacylases from this species have been identified yet. In this study, we investigated two novel enzymes produced by S. griseus DSM 40236ᵀ . We identified and cloned the respective genes and recombinantly expressed an α-aminoacylase (EC 3.5.1.14), designated SgAA, and an ε-lysine acylase (EC 3.5.1.17), designated SgELA, in S. lividans TK23. The purified aminoacylase SgAA was biochemically characterized, focusing on its hydrolytic activity to determine temperature- and pH optima and stabilities. The aminoacylase could hydrolyze various acetyl-amino acids at the Nα -position with a broad specificity regarding the sidechain. Substrates with longer acyl chains, like lauroyl-amino acids, were hydrolyzed to a lesser extent. Purified aminoacylase SgELA specific for the hydrolysis of Nε -acetyl-L-lysine was unstable and lost its enzymatic activity upon storage for a longer period but could initially be characterized. The pH optimum of SgELA was pH 8.0. While synthesis of acyl-amino acids was not observed with SgELA, SgAA catalyzed the synthesis of lauroyl-methionine.},
  language  = {en}
}
@article{WeldenSeverinsPoghossianetal.2022,
  author    = {Welden, Melanie and Severins, Robin and Poghossian, Arshak and Wege, Christina and Bongaerts, Johannes and Siegert, Petra and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Detection of acetoin and diacetyl by a tobacco mosaic virus-assisted field-effect biosensor},
  series = {Chemosensors},
  volume    = {10},
  journal   = {Chemosensors},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2227-9040},
  doi       = {10.3390/chemosensors10060218},
  pages     = {Artikel 218},
  year      = {2022},
  abstract  = {Acetoin and diacetyl have a major impact on the flavor of alcoholic beverages such as wine or beer. Therefore, their measurement is important during the fermentation process. Until now, gas chromatographic techniques have typically been applied; however, these require expensive laboratory equipment and trained staff, and do not allow for online monitoring. In this work, a capacitive electrolyte-insulator-semiconductor sensor modified with tobacco mosaic virus (TMV) particles as enzyme nanocarriers for the detection of acetoin and diacetyl is presented. The enzyme acetoin reductase from Alkalihalobacillus clausii DSM 8716ᵀ is immobilized via biotin-streptavidin affinity, binding to the surface of the TMV particles. The TMV-assisted biosensor is electrochemically characterized by means of leakage-current, capacitance-voltage, and constant capacitance measurements. In this paper, the novel biosensor is studied regarding its sensitivity and long-term stability in buffer solution. Moreover, the TMV-assisted capacitive field-effect sensor is applied for the detection of diacetyl for the first time. The measurement of acetoin and diacetyl with the same sensor setup is demonstrated. Finally, the successive detection of acetoin and diacetyl in buffer and in diluted beer is studied by tuning the sensitivity of the biosensor using the pH value of the measurement solution.},
  language  = {en}
}
@article{AkimbekovDigelTastambeketal.2021,
  author    = {Akimbekov, Nuraly S. and Digel, Ilya and Tastambek, Kuanysh T. and Sherelkhan, Dinara K. and Jussupova, Dariya B. and Altynbay, Nazym P.},
  title     = {Low-rank coal as a source of humic substances for soil amendment and fertility management},
  series = {Agriculture},
  volume    = {11},
  journal   = {Agriculture},
  number    = {12},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2077-0472},
  doi       = {10.3390/agriculture11121261},
  pages     = {25 Seiten},
  year      = {2021},
  abstract  = {Humic substances (HS), as important environmental components, are essential to soil health and agricultural sustainability. The usage of low-rank coal (LRC) for energy generation has declined considerably due to the growing popularity of renewable energy sources and gas. However, their potential as soil amendment aimed to maintain soil quality and productivity deserves more recognition. LRC, a highly heterogeneous material in nature, contains large quantities of HS and may effectively help to restore the physicochemical, biological, and ecological functionality of soil. Multiple emerging studies support the view that LRC and its derivatives can positively impact the soil microclimate, nutrient status, and organic matter turnover. Moreover, the phytotoxic effects of some pollutants can be reduced by subsequent LRC application. Broad geographical availability, relatively low cost, and good technical applicability of LRC offer the advantage of easy fulfilling soil amendment and conditioner requirements worldwide. This review analyzes and emphasizes the potential of LRC and its numerous forms/combinations for soil amelioration and crop production. A great benefit would be a systematic investment strategy implicating safe utilization and long-term application of LRC for sustainable agricultural production.},
  language  = {en}
}
@article{WeldenJablonskiWegeetal.2021,
  author    = {Welden, Rene and Jablonski, Melanie and Wege, Christina and Keusgen, Michael and Wagner, Patrick Hermann and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Light-Addressable Actuator-Sensor Platform for Monitoring and Manipulation of pH Gradients in Microfluidics: A Case Study with the Enzyme Penicillinase},
  series = {Biosensors},
  volume    = {11},
  journal   = {Biosensors},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2079-6374},
  doi       = {10.3390/bios11060171},
  pages     = {Artikel 171},
  year      = {2021},
  abstract  = {The feasibility of light-addressed detection and manipulation of pH gradients inside an electrochemical microfluidic cell was studied. Local pH changes, induced by a light-addressable electrode (LAE), were detected using a light-addressable potentiometric sensor (LAPS) with different measurement modes representing an actuator-sensor system. Biosensor functionality was examined depending on locally induced pH gradients with the help of the model enzyme penicillinase, which had been immobilized in the microfluidic channel. The surface morphology of the LAE and enzyme-functionalized LAPS was studied by scanning electron microscopy. Furthermore, the penicillin sensitivity of the LAPS inside the microfluidic channel was determined with regard to the analyte's pH influence on the enzymatic reaction rate. In a final experiment, the LAE-controlled pH inhibition of the enzyme activity was monitored by the LAPS.},
  language  = {en}
}