@article{PoghossianSchoening2003,
  author    = {Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {"High-order" hybrid FET module for (bio)chemical and physical sensing},
  series = {Integrated analytical systems / ed. by Salvador Alegret},
  journal   = {Integrated analytical systems / ed. by Salvador Alegret},
  publisher = {Elsevier},
  address   = {Amsterdam [u.a.]},
  isbn      = {0-444-51037-0},
  pages     = {587 -- 623},
  year      = {2003},
  language  = {en}
}
@article{BuniatyanMatirosyanAbouzaretal.2009,
  author    = {Buniatyan, V. V. and Matirosyan, N. W. and Abouzar, Maryam H. and Sch{\"o}ning, Michael Josef and Poghossian, Arshak and Schubert, J. and Khachatryan, V. R. and Soukiassyan, G. R.},
  title     = {(Ba,Sr)TiO3 based electrolyte-insulator-semiconductor pHsensors: comparitive study},
  series = {Semiconductor micro- and nanoelectronics : Proceedings of the Seventh International Conference , Tsakhcadzor, Armenia July 3-5 2009},
  journal   = {Semiconductor micro- and nanoelectronics : Proceedings of the Seventh International Conference , Tsakhcadzor, Armenia July 3-5 2009},
  pages     = {71 -- 74},
  year      = {2009},
  language  = {en}
}
@article{PoghossianLuethSchultzeetal.2001,
  author    = {Poghossian, Arshak and L{\"u}th, H. and Schultze, J. W. and Sch{\"o}ning, Michael Josef},
  title     = {(Bio-)chemical and physical microsensor array using an identical transducer principle},
  series = {Scaling down in electrochemistry : electrochemical micro- and nanosystem technology ; proceedings of the 3rd International Symposium on Electrochemical Microsystem Technologies, Garmisch-Patenkirchen, Germany, 11 - 15 September 2000 / ed. by J. W. Schultz},
  journal   = {Scaling down in electrochemistry : electrochemical micro- and nanosystem technology ; proceedings of the 3rd International Symposium on Electrochemical Microsystem Technologies, Garmisch-Patenkirchen, Germany, 11 - 15 September 2000 / ed. by J. W. Schultz},
  publisher = {Elsevier [u.a.]},
  address   = {Amsterdam [u.a.]},
  isbn      = {0-08-044014-2},
  pages     = {243 -- 249},
  year      = {2001},
  language  = {en}
}
@incollection{YoshinobuKrauseMiyamotoetal.2018,
  author    = {Yoshinobu, Tatsuo and Krause, Steffi and Miyamoto, Ko-ichiro and Werner, Frederik and Poghossian, Arshak and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {(Bio-)chemical Sensing and Imaging by LAPS and SPIM},
  series = {Label-free biosensing: advanced materials, devices and applications},
  booktitle = {Label-free biosensing: advanced materials, devices and applications},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-75219-8},
  pages     = {103 -- 132},
  year      = {2018},
  abstract  = {The light-addressable potentiometric sensor (LAPS) and scanning photo-induced impedance microscopy (SPIM) are two closely related methods to visualise the distributions of chemical species and impedance, respectively, at the interface between the sensing surface and the sample solution. They both have the same field-effect structure based on a semiconductor, which allows spatially resolved and label-free measurement of chemical species and impedance in the form of a photocurrent signal generated by a scanning light beam. In this article, the principles and various operation modes of LAPS and SPIM, functionalisation of the sensing surface for measuring various species, LAPS-based chemical imaging and high-resolution sensors based on silicon-on-sapphire substrates are described and discussed, focusing on their technical details and prospective applications.},
  language  = {en}
}
@inproceedings{PoghossianAbouzarSchoening2012,
  author    = {Poghossian, Arshak and Abouzar, Maryam H. and Sch{\"o}ning, Michael Josef},
  title     = {(Bio-­)chemical sensor array based on nanoplate SOI capacitors},
  series = {Nanoscale Science and Technology (NS\&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012},
  booktitle = {Nanoscale Science and Technology (NS\&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012},
  editor    = {Abdelghani, Adnane and Sch{\"o}ning, Michael Josef},
  pages     = {31 -- 31},
  year      = {2012},
  language  = {en}
}
@article{NaetherAugerPoghossianetal.2004,
  author    = {N{\"a}ther, Niko and Auger, V. and Poghossian, Arshak and Koudelka-Hep, M. and Sch{\"o}ning, Michael Josef},
  title     = {A miniaturized flow-through cell in SU-8 technique for EIS sensors},
  series = {Biomedizinische Technik. 49 (2004), H. 2},
  journal   = {Biomedizinische Technik. 49 (2004), H. 2},
  isbn      = {0932-4666},
  pages     = {994 -- 995},
  year      = {2004},
  language  = {en}
}
@inproceedings{BaeckerKochGeigeretal.2016,
  author    = {B{\"a}cker, Matthias and Koch, C. and Geiger, F. and Eber, F. and Gliemann, H. and Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {A New Class of Biosensors Based on Tobacco Mosaic Virus and Coat Proteins as Enzyme Nanocarrier},
  series = {Procedia Engineering},
  volume    = {Vol. 168},
  booktitle = {Procedia Engineering},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2016.11.228},
  pages     = {618 -- 621},
  year      = {2016},
  language  = {en}
}
@inproceedings{SchoeningAbouzarWagneretal.2006,
  author    = {Sch{\"o}ning, Michael Josef and Abouzar, Maryam H. and Wagner, Torsten and N{\"a}ther, Niko and Rolka, David and Yoshinobu, Tatsuo and Kloock, Joachim P. and Turek, Monika and Ingebrandt, Sven and Poghossian, Arshak},
  title     = {A semiconductor-based field-effect platform for (bio-)chemical and physical sensors: From capacitive EIS sensors and LAPS over ISFETs to nano-scale devices},
  series = {MRS Proceedings},
  booktitle = {MRS Proceedings},
  doi       = {10.1557/PROC-0952-F08-02},
  pages     = {1 -- 9},
  year      = {2006},
  language  = {en}
}
@article{BaeckerPouyeshmanSchnitzleretal.2011,
  author    = {B{\"a}cker, Matthias and Pouyeshman, S. and Schnitzler, Thomas and Poghossian, Arshak and Wagner, Patrick and Biselli, Manfred and Sch{\"o}ning, Michael Josef},
  title     = {A silicon-based multi-sensor chip for monitoring of fermentation processes},
  series = {Physica status solidi (a) : applications and material science. 208 (2011), H. 6},
  journal   = {Physica status solidi (a) : applications and material science. 208 (2011), H. 6},
  publisher = {Wiley},
  address   = {Weinheim},
  isbn      = {1862-6319},
  pages     = {1364 -- 1369},
  year      = {2011},
  language  = {en}
}
@article{YoshinobuEckenPoghossianetal.2001,
  author    = {Yoshinobu, T. and Ecken, H. and Poghossian, Arshak and L{\"u}th, H. and Iwasaki, H. and Sch{\"o}ning, Michael Josef},
  title     = {Alternative sensor materials for light-addressable potentiometric sensors},
  series = {Sensors and Actuators B. 76 (2001), H. 1-3},
  journal   = {Sensors and Actuators B. 76 (2001), H. 1-3},
  isbn      = {0925-4005},
  pages     = {388 -- 392},
  year      = {2001},
  language  = {en}
}
@inproceedings{WuPoghossianWerneretal.2013,
  author    = {Wu, Chunsheng and Poghossian, Arshak and Werner, Frederik and Bronder, Thomas and B{\"a}cker, Matthias and Wang, Ping and Sch{\"o}ning, Michael Josef},
  title     = {An application of a scanning light-addressable potentiometric sensor for label-free DNA detection},
  series = {11. Dresdner Sensor-Symposium : 9.-11.12.2013},
  booktitle = {11. Dresdner Sensor-Symposium : 9.-11.12.2013},
  organization    = {Dresdner Sensor-Symposium <11, 2013>},
  isbn      = {978-3-9813484-5-3},
  pages     = {164 -- 168},
  year      = {2013},
  language  = {en}
}
@article{SchusserPoghossianBaeckeretal.2015,
  author    = {Schusser, Sebastian and Poghossian, Arshak and B{\"a}cker, Matthias and Krischer, M. and Leinhos, Marcel and Wagner, P. and Sch{\"o}ning, Michael Josef},
  title     = {An application of field-effect sensors for in-situ monitoring of degradation of biopolymers},
  series = {Sensors and actuators B: Chemical},
  volume    = {207, Part B},
  journal   = {Sensors and actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-3077 (E-Journal); 0925-4005 (Print)},
  doi       = {10.1016/j.snb.2014.10.058},
  pages     = {954 -- 959},
  year      = {2015},
  abstract  = {The characterization of the degradation kinetics of biodegradable polymers is mandatory with regard to their proper application. In the present work, polymer-modified electrolyte-insulator-semiconductor (PMEIS) field-effect sensors have been applied for in-situ monitoring of the pH-dependent degradation kinetics of the commercially available biopolymer poly(d,l-lactic acid) (PDLLA) in buffer solutions from pH 3 to pH 13. PDLLA films of 500 nm thickness were deposited on the surface of an Al-p-Si-SiO2-Ta2O5 structure from a polymer solution by means of spin-coating method. The PMEIS sensor is, in principle, capable to detect any changes in bulk, surface and interface properties of the polymer induced by degradation processes. A faster degradation has been observed for PDLLA films exposed to alkaline solutions (pH 9, pH 11 and pH 13).},
  language  = {en}
}
@article{AbouzarPoghossianPedrazaetal.2011,
  author    = {Abouzar, Maryam H. and Poghossian, Arshak and Pedraza, A. M. and Gandhi, D. and Ingebrandt, S. and Moritz, W. and Sch{\"o}ning, Michael Josef},
  title     = {An array of field-effect nanoplate SOI capacitors for (bio-)chemical sensing},
  series = {Biosensors and Bioelectronics. 26 (2011), H. 6},
  journal   = {Biosensors and Bioelectronics. 26 (2011), H. 6},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {0956-5663},
  pages     = {3023 -- 3028},
  year      = {2011},
  language  = {en}
}
@article{MoseleyHalamekKrameretal.2014,
  author    = {Moseley, Fiona and Halamek, Jan and Kramer, Friederike and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Katz, Evgeny},
  title     = {An enzyme-based reversible CNOT logic gate realized in a flow system},
  series = {Analyst},
  volume    = {139},
  journal   = {Analyst},
  number    = {8},
  publisher = {Royal Society of Chemistry},
  address   = {Cambridge},
  issn      = {1364-5528 (E-Journal) ; 0003-2654 (Print)},
  doi       = {10.1039/C4AN00133H},
  pages     = {1839 -- 1842},
  year      = {2014},
  abstract  = {An enzyme system organized in a flow device was used to mimic a reversible Controlled NOT (CNOT) gate with two input and two output signals. Reversible conversion of NAD⁺ and NADH cofactors was used to perform a XOR logic operation, while biocatalytic hydrolysis of p-nitrophenyl phosphate resulted in an Identity operation working in parallel. The first biomolecular realization of a CNOT gate is promising for integration into complex biomolecular networks and future biosensor/biomedical applications.},
  language  = {en}
}
@article{HonarvarfardGamellaPoghossianetal.2017,
  author    = {Honarvarfard, Elham and Gamella, Maria and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Katz, Evgeny},
  title     = {An enzyme-based reversible Controlled NOT (CNOT) logic gate operating on a semiconductor transducer},
  series = {Applied Materials Today},
  volume    = {9},
  journal   = {Applied Materials Today},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2352-9407},
  doi       = {10.1016/j.apmt.2017.08.003},
  pages     = {266 -- 270},
  year      = {2017},
  abstract  = {An enzyme-based biocatalytic system mimicking operation of a logically reversible Controlled NOT (CNOT) gate has been interfaced with semiconductor electronic transducers. Electrolyte-insulator-semiconductor (EIS) structures have been used to transduce chemical changes produced by the enzyme system to an electronically readable capacitive output signal using field-effect features of the EIS device. Two enzymes, urease and esterase, were immobilized on the insulating interface of EIS structure producing local pH changes performing XOR logic operation controlled by various combinations of the input signals represented by urea and ethyl butyrate. Another EIS transducer was functionalized with esterase only, thus performing Identity (ID) logic operation for the ethyl butyrate input. Both semiconductor devices assembled in parallel operated as a logically reversible CNOT gate. The present system, despite its simplicity, demonstrated for the first time logically reversible function of the enzyme system transduced electronically with the semiconductor devices. The biomolecular realization of a CNOT gate interfaced with semiconductors is promising for integration into complex biomolecular networks and future biosensor/biomedical applications.},
  language  = {en}
}
@article{PoghossianSchoeningSchrothetal.2001,
  author    = {Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Schroth, P. and Simonis, A. and L{\"u}th, H.},
  title     = {An ISFET-based penicillin sensor with high sensitivity, low detection limit and long lifetime},
  series = {Sensors and Actuators B. 76 (2001), H. 1-3},
  journal   = {Sensors and Actuators B. 76 (2001), H. 1-3},
  isbn      = {0925-4005},
  pages     = {519 -- 526},
  year      = {2001},
  language  = {en}
}
@article{PoghossianSchultzeSchoening2003,
  author    = {Poghossian, Arshak and Schultze, J. W. and Sch{\"o}ning, Michael Josef},
  title     = {Application of a (bio-)chemical sensor (ISFET) for the detection of physical parameters in liquids},
  series = {Electrochimica Acta. 48 (2003), H. 20-22},
  journal   = {Electrochimica Acta. 48 (2003), H. 20-22},
  pages     = {3289 -- 3297},
  year      = {2003},
  language  = {en}
}
@article{PoghossianBaadeEmonsetal.2001,
  author    = {Poghossian, Arshak and Baade, A. and Emons, H. and Sch{\"o}ning, Michael Josef},
  title     = {Application of ISFET for pH measurements in rain droplets},
  series = {Sensors and Actuators B. 76 (2001), H. 1-3},
  journal   = {Sensors and Actuators B. 76 (2001), H. 1-3},
  isbn      = {0925-4005},
  pages     = {634 -- 638},
  year      = {2001},
  language  = {en}
}
@article{SiqueiraBaeckerPoghossianetal.2010,
  author    = {Siqueira, Jos{\´e} R. Jr. and B{\"a}cker, Matthias and Poghossian, Arshak and Zucolotto, Valtencir and Oliveira, Osvaldo N. Jr. and Sch{\"o}ning, Michael Josef},
  title     = {Associating biosensing properties with the morphological structure of multilayers containing carbon nanotubes on field-effect devices},
  series = {Physica status solidi (a). 207 (2010), H. 4},
  journal   = {Physica status solidi (a). 207 (2010), H. 4},
  isbn      = {1862-6300},
  pages     = {781 -- 786},
  year      = {2010},
  language  = {en}
}
@article{PoghossianWagnerSchoening2010,
  author    = {Poghossian, Arshak and Wagner, H. and Sch{\"o}ning, Michael Josef},
  title     = {Automatisiertes „wafer level"-Testsystem zur Charakterisierung von siliziumbasierten Chemo- und Biosensoren},
  series = {Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vortr{\"a}ge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in N{\"u}rnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA)},
  journal   = {Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vortr{\"a}ge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in N{\"u}rnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA)},
  publisher = {VDE Verlag},
  address   = {Berlin},
  isbn      = {978-3-8007-3260-9},
  pages     = {89 -- 92},
  year      = {2010},
  language  = {de}
}
@article{BuniatyanHuckPoghossianetal.2013,
  author    = {Buniatyan, V. and Huck, Christina and Poghossian, Arshak and Aroutiounian, V. M. and Sch{\"o}ning, Michael Josef},
  title     = {BaxSr1-x TiO3/pc-Si heterojunction},
  series = {Armenian journal of physics},
  volume    = {6},
  journal   = {Armenian journal of physics},
  number    = {4},
  publisher = {National Academy of Sciences of Armenia},
  address   = {Yerevan},
  issn      = {1829-1171},
  pages     = {177 -- 187},
  year      = {2013},
  language  = {en}
}
@article{BuniatyanHuckPoghossianetal.2013,
  author    = {Buniatyan, V. and Huck, Christina and Poghossian, Arshak and Aroutiounian, V. M. and Sch{\"o}ning, Michael Josef},
  title     = {BaxSr1-x TiO3/pc-Si heterojunction capacitance},
  series = {Armenian journal of physics},
  volume    = {6},
  journal   = {Armenian journal of physics},
  number    = {4},
  publisher = {National Academy of Sciences of Armenia},
  address   = {Yerevan},
  issn      = {1829-1171},
  pages     = {188 -- 197},
  year      = {2013},
  language  = {en}
}
@inproceedings{HuckBaeckerPoghossianetal.2011,
  author    = {Huck, Christina and B{\"a}cker, Matthias and Poghossian, Arshak and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Bifunktionaler Sensorchip f{\"u}r den Nachweis von Gel{\"o}stwasserstoff},
  isbn      = {978-3942710-53-4},
  doi       = {10.5162/10dss2011/16.10},
  pages     = {325 -- 328},
  year      = {2011},
  language  = {de}
}
@article{KramerHalamkovaPoghossianetal.2013,
  author    = {Kramer, Friederike and Halamkova, Lenka and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Katz, Evgeny and Halamek, Jan},
  title     = {Biocatalytic analysis of biomarkers for forensic identification of ethnicity between Caucasian and African American},
  series = {The analyst. August 2013},
  volume    = {Vol. 138},
  journal   = {The analyst. August 2013},
  publisher = {Royal Society of Chemistry},
  address   = {Cambridge},
  issn      = {1364-5528 (E-Journal); 0003-2654 (Print)},
  pages     = {6251 -- 6257},
  year      = {2013},
  language  = {en}
}
@article{SchoeningPoghossian2006,
  author    = {Sch{\"o}ning, Michael Josef and Poghossian, Arshak},
  title     = {BioFEDs (field-effect devices) : State-of-the-art and new directions},
  series = {Electroanalysis},
  volume    = {18},
  journal   = {Electroanalysis},
  number    = {19-20},
  issn      = {1521-4109},
  doi       = {10.1002/elan.200603609},
  pages     = {1893 -- 1900},
  year      = {2006},
  language  = {en}
}
@inproceedings{SchusserLeinhosPoghossianetal.2012,
  author    = {Schusser, Sebastian and Leinhos, Marcel and Poghossian, Arshak and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Biopolymer-degradation monitoring by chip-­based impedance spectroscopy technique},
  series = {Nanoscale Science and Technology (NS\&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012},
  booktitle = {Nanoscale Science and Technology (NS\&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012},
  editor    = {Abdelghani, Adnane and Sch{\"o}ning, Michael Josef},
  pages     = {47 -- 47},
  year      = {2012},
  language  = {en}
}
@article{PoghossianAbouzarSchoening2008,
  author    = {Poghossian, Arshak and Abouzar, Maryam H. and Sch{\"o}ning, Michael Josef},
  title     = {Capacitance-voltage and impedance characteristics of field-effect EIS sensors functionalised with polyelectrolyte multilayers},
  series = {IRBM. 29 (2008), H. 2-3},
  journal   = {IRBM. 29 (2008), H. 2-3},
  isbn      = {1959-0318},
  pages     = {149 -- 154},
  year      = {2008},
  language  = {en}
}
@article{AbouzarWernerSchoeningetal.2011,
  author    = {Abouzar, Maryam H. and Werner, Moritz and Sch{\"o}ning, Michael Josef and Poghossian, Arshak},
  title     = {Capacitance-voltage and impedance-spectroscopy characteristics of nanoplate EISOI capacitors},
  series = {Physica status solidi (a) : applications and material science. 208 (2011), H. 6},
  journal   = {Physica status solidi (a) : applications and material science. 208 (2011), H. 6},
  publisher = {Wiley-VCH},
  address   = {Berlin},
  isbn      = {1862-6319},
  pages     = {1327 -- 1332},
  year      = {2011},
  language  = {en}
}
@article{AbouzarPoghossianSiqueiraetal.2010,
  author    = {Abouzar, Maryam H. and Poghossian, Arshak and Siqueira, Jos{\´e} R. Jr. and Oliveira, Osvaldo N. Jr. and Moritz, Werner and Sch{\"o}ning, Michael Josef},
  title     = {Capacitive electrolyte-insulator-semiconductor structures functionalised with a polyelectrolyte/enzyme multilayer: New strategy for enhanced field-effect biosensing},
  series = {Physica Status Solidi (A). 207 (2010), H. 4},
  journal   = {Physica Status Solidi (A). 207 (2010), H. 4},
  isbn      = {1862-6300},
  pages     = {884 -- 890},
  year      = {2010},
  language  = {en}
}
@article{BaeckerPoghossianAbouzaretal.2010,
  author    = {B{\"a}cker, Matthias and Poghossian, Arshak and Abouzar, Maryam H. and Wenmackers, Sylvia and Janssens, Stoffel D. and Haenen, Ken and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Capacitive field-effect (bio-)chemical sensors based on nanocrystalline diamond films},
  series = {Diamond Electronics and Bioelectronics — Fundamentals to Applications III, edited by P. Bergonzo, [u.a.]},
  journal   = {Diamond Electronics and Bioelectronics — Fundamentals to Applications III, edited by P. Bergonzo, [u.a.]},
  pages     = {1 -- 6},
  year      = {2010},
  language  = {en}
}
@article{JablonskiPoghossianSeverinetal.2021,
  author    = {Jablonski, Melanie and Poghossian, Arshak and Severin, Robin and Keusgen, Michael and Wege, Christian and Sch{\"o}ning, Michael Josef},
  title     = {Capacitive Field-Effect Biosensor Studying Adsorption of Tobacco Mosaic Virus Particles},
  series = {Micromachines},
  volume    = {12},
  journal   = {Micromachines},
  number    = {1},
  publisher = {MDPI},
  address   = {Basel},
  doi       = {10.3390/mi12010057},
  pages     = {Artikel 57},
  year      = {2021},
  abstract  = {Plant virus-like particles, and in particular, tobacco mosaic virus (TMV) particles, are increasingly being used in nano- and biotechnology as well as for biochemical sensing purposes as nanoscaffolds for the high-density immobilization of receptor molecules. The sensitive parameters of TMV-assisted biosensors depend, among others, on the density of adsorbed TMV particles on the sensor surface, which is affected by both the adsorption conditions and surface properties of the sensor. In this work, Ta₂O₅-gate field-effect capacitive sensors have been applied for the label-free electrical detection of TMV adsorption. The impact of the TMV concentration on both the sensor signal and the density of TMV particles adsorbed onto the Ta₂O₅-gate surface has been studied systematically by means of field-effect and scanning electron microscopy methods. In addition, the surface density of TMV particles loaded under different incubation times has been investigated. Finally, the field-effect sensor also demonstrates the label-free detection of penicillinase immobilization as model bioreceptor on TMV particles.},
  language  = {en}
}
@article{PoghossianSchoening2020,
  author    = {Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {Capacitive field-effect eis chemical sensors and biosensors: A status report},
  series = {Sensors},
  volume    = {20},
  journal   = {Sensors},
  number    = {19},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s20195639},
  pages     = {Artikel 5639},
  year      = {2020},
  abstract  = {Electrolyte-insulator-semiconductor (EIS) field-effect sensors belong to a new generation of electronic chips for biochemical sensing, enabling a direct electronic readout. The review gives an overview on recent advances and current trends in the research and development of chemical sensors and biosensors based on the capacitive field-effect EIS structure—the simplest field-effect device, which represents a biochemically sensitive capacitor. Fundamental concepts, physicochemical phenomena underlying the transduction mechanism and application of capacitive EIS sensors for the detection of pH, ion concentrations, and enzymatic reactions, as well as the label-free detection of charged molecules (nucleic acids, proteins, and polyelectrolytes) and nanoparticles, are presented and discussed.},
  language  = {en}
}
@article{BuniatyanMatirosyanAbouzaretal.2009,
  author    = {Buniatyan, Vahe V. and Matirosyan, N. and Abouzar, Maryam H. and Schubert, J. and Zander, W. and Gevorgian, S. and Sch{\"o}ning, Michael Josef and Poghossian, Arshak},
  title     = {Capacitive field-effect pH sensor based on an electrolyte-ferroelectric-insulator-semiconductor structure},
  series = {SENSOR 2009 : : 14th International Conference on Sensors, Technologies, Electronics and Applications; N{\"u}rnberg, Germany, 26 - 28 May 2009; proceedings; [part of] Sensor + Test Conference 2009 / AMA, Fachverband f{\"u}r Sensorik e.V},
  journal   = {SENSOR 2009 : : 14th International Conference on Sensors, Technologies, Electronics and Applications; N{\"u}rnberg, Germany, 26 - 28 May 2009; proceedings; [part of] Sensor + Test Conference 2009 / AMA, Fachverband f{\"u}r Sensorik e.V},
  publisher = {AMA Service},
  address   = {Wunstorf},
  isbn      = {9783981099355},
  pages     = {317 -- 322},
  year      = {2009},
  language  = {en}
}
@article{KarschuckPoghossianSeretal.2024,
  author    = {Karschuck, Tobias and Poghossian, Arshak and Ser, Joey and Tsokolakyan, Astghik and Achtsnicht, Stefan and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Capacitive model of enzyme-modified field-effect biosensors: Impact of enzyme coverage},
  series = {Sensors and Actuators B: Chemical},
  volume    = {408},
  journal   = {Sensors and Actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005 (Print)},
  doi       = {10.1016/j.snb.2024.135530},
  pages     = {12 Seiten},
  year      = {2024},
  abstract  = {Electrolyte-insulator-semiconductor capacitors (EISCAP) belong to field-effect sensors having an attractive transducer architecture for constructing various biochemical sensors. In this study, a capacitive model of enzyme-modified EISCAPs has been developed and the impact of the surface coverage of immobilized enzymes on its capacitance-voltage and constant-capacitance characteristics was studied theoretically and experimentally. The used multicell arrangement enables a multiplexed electrochemical characterization of up to sixteen EISCAPs. Different enzyme coverages have been achieved by means of parallel electrical connection of bare and enzyme-covered single EISCAPs in diverse combinations. As predicted by the model, with increasing the enzyme coverage, both the shift of capacitance-voltage curves and the amplitude of the constant-capacitance signal increase, resulting in an enhancement of analyte sensitivity of the EISCAP biosensor. In addition, the capability of the multicell arrangement with multi-enzyme covered EISCAPs for sequentially detecting multianalytes (penicillin and urea) utilizing the enzymes penicillinase and urease has been experimentally demonstrated and discussed.},
  language  = {en}
}
@article{HuckPoghossianBaeckeretal.2014,
  author    = {Huck, Christina and Poghossian, Arshak and B{\"a}cker, Matthias and Chaudhuri, S. and Zander, W. and Schubert, J. and Begoyan, V. K. and Buniatyan, V. V. and Wagner, P. and Sch{\"o}ning, Michael Josef},
  title     = {Capacitively coupled electrolyte-conductivity sensor based on high-k material of barium strontium titanate},
  series = {Sensors and actuators. B: Chemical},
  journal   = {Sensors and actuators. B: Chemical},
  number    = {198},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-3077 (E-Journal); 0925-4005 (Print)},
  doi       = {10.1016/j.snb.2014.02.103},
  pages     = {102 -- 109},
  year      = {2014},
  language  = {en}
}
@article{SiqueiraAbouzarBaeckeretal.2009,
  author    = {Siqueira, Jos{\´e} R. Jr. and Abouzar, Maryam H. and B{\"a}cker, Matthias and Zucolotto, Valtencir and Poghossian, Arshak and Oliveira, Osvaldo N. Jr. and Sch{\"o}ning, Michael Josef},
  title     = {Carbon nanotubes in nanostructured films: Potential application as amperometric and potentiometric field-effect (bio-)chemical sensors},
  series = {physica status solidi (a) . 206 (2009), H. 3},
  journal   = {physica status solidi (a) . 206 (2009), H. 3},
  publisher = {Wiley},
  address   = {Weinheim},
  isbn      = {1862-6319},
  pages     = {462 -- 467},
  year      = {2009},
  language  = {en}
}
@article{AbouzarPoghossianRazavietal.2009,
  author    = {Abouzar, Maryam H. and Poghossian, Arshak and Razavi, A. and Williams, O. A. and Bijnens, N. and Wagner, P. and Sch{\"o}ning, Michael Josef},
  title     = {Characterisation of capacitive field-effect sensors with a nanocrystalline-diamond film as transducer material for multi-parameter sensing},
  series = {Biosensors and Bioelectronics. 24 (2009), H. 5},
  journal   = {Biosensors and Bioelectronics. 24 (2009), H. 5},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {0956-5663},
  pages     = {1298 -- 1304},
  year      = {2009},
  language  = {en}
}
@article{SchusserPoghossianBaeckeretal.2012,
  author    = {Schusser, Sebastian and Poghossian, Arshak and B{\"a}cker, Matthias and Leinhos, Marcel and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Characterization of biodegradable polymers with capacitive field-effect sensors},
  series = {Sensors and actuators B: Chemical},
  volume    = {187},
  journal   = {Sensors and actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2012.07.099},
  pages     = {2 -- 7},
  year      = {2012},
  abstract  = {In vitro studies of the degradation kinetic of biopolymers are essential for the design and optimization of implantable biomedical devices. In the presented work, a field-effect capacitive sensor has been applied for the real-time and in situ monitoring of degradation processes of biopolymers for the first time. The polymer-covered field-effect sensor is, in principle, capable to detect any changes in bulk, surface and interface properties of the polymer induced by degradation processes. The feasibility of this approach has been experimentally proven by using the commercially available biomedical polymer poly(D,L-lactic acid) (PDLLA) as a model system. PDLLA films of different thicknesses were deposited on the Ta₂O₅-gate surface of the field-effect structure from a polymer solution by means of spin-coating method. The polymer-modified field-effect sensors have been characterized by means of capacitance-voltage and impedance-spectroscopy method. The degradation of the PDLLA was accelerated by changing the degradation medium from neutral (pH 7.2) to alkaline (pH 9) condition, resulting in drastic changes in the capacitance and impedance spectra of the polymer-modified field-effect sensor.},
  language  = {en}
}
@article{KnobbeSchoeningPoghossianetal.2004,
  author    = {Knobbe, D.-T. and Sch{\"o}ning, Michael Josef and Poghossian, Arshak and Mourzina, Y.},
  title     = {Charakterisierung von kapazitiven EMISSensoren mittels Impedanzspektroskopie, Kapazit{\"a}ts-Spannungs- und Konstant-Kapazit{\"a}ts-Messung},
  series = {Sensoren und Messsysteme 2004 : Tagung Ludwigsburg, 15. und 16. M{\"a}rz 2004 / VDI-VDE-Gesellschaft Mess- und Automatisierungstechnik},
  journal   = {Sensoren und Messsysteme 2004 : Tagung Ludwigsburg, 15. und 16. M{\"a}rz 2004 / VDI-VDE-Gesellschaft Mess- und Automatisierungstechnik},
  publisher = {VDI},
  address   = {D{\"u}sseldorf},
  isbn      = {3-18-091829-2},
  pages     = {851 -- 854},
  year      = {2004},
  language  = {de}
}
@article{PoghossianSchoening2007,
  author    = {Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {Chemical and biological field-effect sensors for liquids - a status report},
  series = {Handbook of biosensors and biochips / ed. Robert S. Marks ... Bd. 1},
  journal   = {Handbook of biosensors and biochips / ed. Robert S. Marks ... Bd. 1},
  publisher = {Wiley},
  address   = {Chichester},
  isbn      = {978-0-470-01905-4},
  pages     = {395 -- 412},
  year      = {2007},
  language  = {en}
}
@article{PoghossianBerndsenSchoening2002,
  author    = {Poghossian, Arshak and Berndsen, L. and Sch{\"o}ning, Michael Josef},
  title     = {Chemical sensor as a physical sensor: ISFET-based flowvelocity, flow-direction and diffusion-coefficient sensor},
  series = {Book of abstracts / ed. by J. Saneistr.},
  journal   = {Book of abstracts / ed. by J. Saneistr.},
  publisher = {Czech Technical University, Faculty of Electrical Engineering, Department of Measurement},
  address   = {Prague},
  isbn      = {80-01-02576-4},
  pages     = {649 -- 652},
  year      = {2002},
  language  = {en}
}
@article{PoghossianBerndsenSchoening2003,
  author    = {Poghossian, Arshak and Berndsen, Lars and Sch{\"o}ning, Michael Josef},
  title     = {Chemical sensor as physical sensor: ISFET-based flowvelocity, flow-direction and diffusion-coefficient sensor},
  series = {Sensors and Actuators B. 95 (2003), H. 1-3},
  journal   = {Sensors and Actuators B. 95 (2003), H. 1-3},
  isbn      = {0925-4005},
  pages     = {384 -- 390},
  year      = {2003},
  language  = {en}
}
@article{HuckPoghossianBaeckeretal.2014,
  author    = {Huck, Christina and Poghossian, Arshak and B{\"a}cker, Matthias and Reisert, Steffen and Schubert, J. and Zander, W. and Begoyan, V. K. and Buniatyan, V. V. and Sch{\"o}ning, Michael Josef},
  title     = {Chemical sensors based on a high-k perovskite oxide of barium strontium titanate},
  series = {Procedia Engineering},
  volume    = {87},
  journal   = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2014.11.258},
  pages     = {28 -- 31},
  year      = {2014},
  abstract  = {High-k perovskite oxide of barium strontium titanate (BST) represents a very attractive multi-functional transducer material for the development of (bio-)chemical sensors for liquids. In this work, BST films have been applied as a sensitive transducer material for a label-free detection of adsorbed charged macromolecules (positively charged polyelectrolytes) and concentration of hydrogen peroxide vapor as well as protection insulator layer for a contactless electrolyte-conductivity sensor. The experimental results of characterization of individual sensors are presented. Special emphasis is devoted towards the development of a capacitively-coupled contactless electrolyte-conductivity sensor.},
  language  = {en}
}
@inproceedings{HuckPoghossianBaeckeretal.2013,
  author    = {Huck, Christina and Poghossian, Arshak and B{\"a}cker, Matthias and Zander, W. and Schubert, J. and Sukoyan, L. H. and Begoyan, V. and Buniatyan, V. V. and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Chemische Sensoren mit Bariumstrontiumtitanat als funktionelle Schicht zur Multiparameterdetektion},
  series = {11. Dresdner Sensor-Symposium : 9.-11.12.2013},
  booktitle = {11. Dresdner Sensor-Symposium : 9.-11.12.2013},
  organization    = {Dresdner Sensor-Symposium <11, 2013>},
  isbn      = {978-3-9813484-5-3},
  pages     = {368 -- 372},
  year      = {2013},
  language  = {de}
}
@article{BaeckerRakowskiPoghossianetal.2013,
  author    = {B{\"a}cker, Matthias and Rakowski, D. and Poghossian, Arshak and Biselli, Manfred and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Chip-based amperometric enzyme sensor system for monitoring of bioprocesses by flow-injection analysis},
  series = {Journal of Biotechnology},
  volume    = {163},
  journal   = {Journal of Biotechnology},
  number    = {4},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0168-1656},
  doi       = {10.1016/j.jbiotec.2012.03.014},
  pages     = {371 -- 376},
  year      = {2013},
  abstract  = {A microfluidic chip integrating amperometric enzyme sensors for the detection of glucose, glutamate and glutamine in cell-culture fermentation processes has been developed. The enzymes glucose oxidase, glutamate oxidase and glutaminase were immobilized by means of cross-linking with glutaraldehyde on platinum thin-film electrodes integrated within a microfluidic channel. The biosensor chip was coupled to a flow-injection analysis system for electrochemical characterization of the sensors. The sensors have been characterized in terms of sensitivity, linear working range and detection limit. The sensitivity evaluated from the respective peak areas was 1.47, 3.68 and 0.28 μAs/mM for the glucose, glutamate and glutamine sensor, respectively. The calibration curves were linear up to a concentration of 20 mM glucose and glutamine and up to 10 mM for glutamate. The lower detection limit amounted to be 0.05 mM for the glucose and glutamate sensor, respectively, and 0.1 mM for the glutamine sensor. Experiments in cell-culture medium have demonstrated a good correlation between the glutamate, glutamine and glucose concentrations measured with the chip-based biosensors in a differential-mode and the commercially available instrumentation. The obtained results demonstrate the feasibility of the realized microfluidic biosensor chip for monitoring of bioprocesses.},
  language  = {en}
}
@article{MolinnusHardtKaeveretal.2018,
  author    = {Molinnus, Denise and Hardt, G. and K{\"a}ver, L. and Willenberg, H.S. and Kr{\"o}ger, J.-C. and Poghossian, Arshak and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Chip-based biosensor for the detection of low adrenaline concentrations to support adrenal venous sampling},
  series = {Sensor and Actuators B: Chemical},
  volume    = {272},
  journal   = {Sensor and Actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2018.05.136},
  pages     = {21 -- 27},
  year      = {2018},
  abstract  = {A chip-based amperometric biosensor referring on using the bioelectrocatalytical amplification principle for the detection of low adrenaline concentrations is presented. The adrenaline biosensor has been prepared by modification of a platinum thin-film electrode with an enzyme membrane containing the pyrroloquinoline quinone-dependent glucose dehydrogenase and glutaraldehyde. Measuring conditions such as temperature, pH value, and glucose concentration have been optimized to achieve a high sensitivity and a low detection limit of about 1 nM adrenaline measured in phosphate buffer at neutral pH value. The response of the biosensor to different catecholamines has also been proven. Long-term stability of the adrenaline biosensor has been studied over 10 days. In addition, the biosensor has been successfully applied for adrenaline detection in human blood plasma for future biomedical applications. Furthermore, preliminary experiments have been carried to detect the adrenaline-concentration difference measured in peripheral blood and adrenal venous blood, representing the adrenal vein sampling procedure of a physician.},
  language  = {en}
}
@article{SchoeningBrinkmannRolkaetal.2005,
  author    = {Sch{\"o}ning, Michael Josef and Brinkmann, D. and Rolka, David and Demuth, C. and Poghossian, Arshak},
  title     = {CIP (cleaning-in-place) suitable "non-glass" pH sensor based on a Ta2O5-gate EIS structure},
  series = {Sensors and Actuators B: Chemical. 111-112 (2005)},
  journal   = {Sensors and Actuators B: Chemical. 111-112 (2005)},
  isbn      = {0925-4005},
  pages     = {423 -- 429},
  year      = {2005},
  language  = {en}
}
@article{SchoeningBrinkmannDemuthetal.2004,
  author    = {Sch{\"o}ning, Michael Josef and Brinkmann, D. and Demuth, C. and Poghossian, Arshak},
  title     = {CIP (cleaning-in-place)-suitable „non-glass" pH sensor based on a Ta2O5-gate EIS structure},
  series = {Digest of technical papers : September 12 - 15, 2004, Rome, Italy, Pontificia Universitas Sancto Thoma Aquinate in Urbe / [conference chairperson: C. Di Natale].},
  journal   = {Digest of technical papers : September 12 - 15, 2004, Rome, Italy, Pontificia Universitas Sancto Thoma Aquinate in Urbe / [conference chairperson: C. Di Natale].},
  address   = {Roma},
  isbn      = {88-7621-282-5},
  pages     = {857 -- 860},
  year      = {2004},
  language  = {en}
}
@article{HuckPoghossianWagneretal.2012,
  author    = {Huck, Christina and Poghossian, Arshak and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Combined amperometric/field-effect sensor for the detection of dissolved hydrogen},
  series = {Sensors and actuators B: Chemical},
  volume    = {187},
  journal   = {Sensors and actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2012.10.050},
  pages     = {168 -- 173},
  year      = {2012},
  abstract  = {Real-time and reliable monitoring of the biogas process is crucial for a stable and efficient operation of biogas production in order to avoid digester breakdowns. The concentration of dissolved hydrogen (H₂) represents one of the key parameters for biogas process control. In this work, a one-chip integrated combined amperometric/field-effect sensor for monitoring the dissolved H₂ concentration has been developed for biogas applications. The combination of two different transducer principles might allow a more accurate and reliable measurement of dissolved H₂ as an early warning indicator of digester failures. The feasibility of the approach has been demonstrated by simultaneous amperometric/field-effect measurements of dissolved H₂ concentrations in electrolyte solutions. Both, the amperometric and the field-effect transducer show a linear response behaviour in the H₂ concentration range from 0.1 to 3\% (v/v) with a slope of 198.4 ± 13.7 nA/\% (v/v) and 14.9 ± 0.5 mV/\% (v/v), respectively.},
  language  = {en}
}
@article{MolinnusBaeckerIkenetal.2015,
  author    = {Molinnus, Denise and B{\"a}cker, Matthias and Iken, Heiko and Poghossian, Arshak and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Concept for a biomolecular logic chip with an integrated sensor and actuator function},
  series = {Physica status solidi (a)},
  volume    = {212},
  journal   = {Physica status solidi (a)},
  number    = {6},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201431913},
  pages     = {1382 -- 1388},
  year      = {2015},
  abstract  = {A concept for a new generation of an integrated multi-functional biosensor/actuator system is developed, which is based on biomolecular logic principles. Such a system is expected to be able to detect multiple biochemical input signals simultaneously and in real-time and convert them into electrical output signals with logical operations such as OR, AND, etc. The system can be designed as a closed-loop drug release device triggered by an enzyme logic gate, while the release of the drug induced by the actuator at the required dosage and timing will be controlled by an additional drug sensor. Thus, the system could help to make an accurate and specific diagnosis. The presented concept is exemplarily demonstrated by using an enzyme logic gate based on a glucose/glucose oxidase system, a temperature-responsive hydrogel mimicking the actuator function and an insulin (drug) sensor. In this work, the results of functional testing of individual amperometric glucose and insulin sensors as well as an impedimetric sensor for the detection of the hydrogel swelling/shrinking are presented.},
  language  = {en}
}